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From economics and business to the biological sciences to physics and engineering, professionals successfully use the powerful mathematical tool of optimal control to make management and strategy decisions. Optimal Control Applied to Biological Models thoroughly develops the mathematical aspects of optimal control theory and provides insight into the application of this theory to biological models.

Focusing on mathematical concepts, the book first examines the most basic problem for continuous time ordinary differential equations (ODEs) before discussing more complicated problems, such as variations of the initial conditions, imposed bounds on the control, multiple states and controls, linear dependence on the control, and free terminal time. In addition, the authors introduce the optimal control of discrete systems and of partial differential equations (PDEs).

Featuring a user-friendly interface, the book contains fourteen interactive sections of various applications, including immunology and epidemic disease models, management decisions in harvesting, and resource allocation models. It also develops the underlying numerical methods of the applications and includes the MATLAB® codes on which the applications are based.

Requiring only basic knowledge of multivariable calculus, simple ODEs, and mathematical models, this text shows how to adjust controls in biological systems in order to achieve proper outcomes. ... Read more

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This is an excellent introductory book on optimal control applied to biological models. It covers a variety of topics including optimal control on ODEs, PDEs and discrete system. The 14 Labs with Matlab codes with user-friendly interface provided on the web offer a good resource to manipulate and learn the materials. The last chapter about other approaches and extensions opens a new horizon. ... Read more

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Molecular microbiology is a rapidly expanding area of contemporary science: the application of molecular biology has opened up the microbial world in many remarkable ways. The attraction of microbes is that they are self-contained and that they offer complete solutions to understanding the phenomenon of life. This book provides a concise introduction to current research in the field. Four major areas are introduced and explained: - Bacterial Biochemistry - Bacterial Genomes - Gene Expression - Microbial Cell Biology ... Read more

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This is a reproduction of a book published before 1923.This book may have occasional imperfections such as missing or blurred pages, poor pictures, errant marks, etc. that were either part of the original artifact, or were introduced by the scanning process.We believe this work is culturally important, and despite the imperfections, have elected to bring it back into print as part of our continuing commitment to the preservation of printed works worldwide.We appreciate your understanding of the imperfections in the preservation process, and hope you enjoy this valuable book. ... Read more

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With the launch of its first electronic edition, The Prokaryotes, the definitive reference on the biology of bacteria, enters an exciting new era of information delivery. Subscription-based access is available.

The electronic version begins with an online implementation of the content found in the printed reference work, The Prokaryotes, Second Edition. The content is being fully updated over a five-year period until the work is completely revised. Thereafter, material will be continuously added to reflect developments in bacteriology. This online version features information retrieval functions and multimedia components.

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High Quality Content by WIKIPEDIA articles! Gut flora consists of microorganisms that live in the digestive tracts of animals, and is the largest reservoir of human flora. "Gut" (the adjective) is synonymous with intestinal and "flora" with microbiota and microflora. The human body, consisting of about 70,000,000,000,000 to 100 trillion cells, carries about ten times as many microorganisms in the intestines. The metabolic activities performed by these bacteria resemble those of an organ, leading some to liken gut bacteria to a "forgotten" organ. Bacteria make up most of the flora in the colon and 60% of the dry mass of feces.Somewhere between 300 and 1000 different species live in the gut, with most estimates at about 500. However, it is probable that 99% of the bacteria come from about 30 or 40 species. Fungi and protozoa also make up a part of the gut flora, but little is known about their activities. ... Read more

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Introduces undergraduates to the diversity and importance of anaerobic bacteria. The author outlines the mechanisms of anaerobic metabolism and then goes on to discuss the principle anaerobic infections of man and animals. Industrial applications of anaerobes are also discussed. ... Read more

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Often thought to lack significant internal organization by comparison with eukaryotic cells, prokaryotes have in fact been shown to possess distinct intracellular compartments. Moreover, they also have cytoskeletal filaments reminiscent of those in higher organisms. Recent work has significantly extended our understanding of these features of prokaryotic cells and their roles in control of cell division, morphogenesis, and other processes. The book covers all aspects of prokaryotic cell biology, including the bacterial cytoskeleton, membrane organization, chromosome dynamics, nucleic acid processing and dynamics, as well as various methods. ... Read more

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This book constitutes the first comprehensive discussion and collection of facts and functions of unconventional secretory pathways, some of which are of importance in human disease and pathology. The function of ABC transporters in these processes is also discussed. This comparison of common aspects and similarities in all living cells - from bacteria to man - is an excellent reference book with "textbook" character. ... Read more