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This authoritative reference brings together current knowledge in the field of respiratory genetics in a single volume for the first time. The book includes a comprehensive introductory section to provide guidance and aid understanding of key basic concepts in respiratory genetics, including statistical methods, sample collection and storage, bioinformatics, and molecular genetics. This is followed by a series of disease-specific chapters which review epidemiology; natural history; monogenic components and complex traits where relevant; disease management, including genetic counseling issues; and likely future developments. Chapters are written in a uniform structure--ensuring consistency of approach throughout--and each concludes with a summary highlighting practical "take-home" messages regarding patient management for the reader. It is also highly illustrated, including color plates where appropriate. ... Read more

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Genetics promises to provide one of the most powerful approaches to understanding the functional pathology of the human brain.This book presents a critical review of the evidence for a genetic contribution to common psychiatric conditions and the rarer single-gene disorders that may have psychiatric presentations The first section of the book introduces the reader to molecular biology and the techniques of molecular genetics.The coverage then moves on to consider the genetics of normal and abnormal development, followed by a look at the genetics of abnormal behaviour in adults.This section includes, amongst others, consideration of personality disorders, schizophrenia and the dementias.The final section considers the applications of the work and covers issues such as counselling and ethics, closing with a look to the future. The editors are internationally renowned figures in this field and they have invited a team of equally eminent chapter authors. This will be essential reading for psychiatrists and geneticists and will be essential reading for psychiatrists and geneticists and will be of interest to neurologists, psychologists and neuroscientists. ... Read more

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The very rapid advances in biochemical technology recently have helped identify the basic defect in about 250 genetic disorders. Early precise diagnosis is essential before therapy can be identified which will lead to survival and normal development. This book describes clinical, pathological, and biochemical features, diagnostic methodology, and the necessary data for genetic counselling. ... Read more

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In the first book of its kind, Genetics, Biotechnology and Breeding of Maize and Sorghum combines present knowledge from the three fields in one volume. The latest research from international experts on maize transformation and the development and testing of transgenic maize is presented, including data on maize genome analysis, DNA methylation, molecular biology and genetic engineering techniques and QTL analysis. This unique book indicates our present state of knowledge in this important and broad field, with particular emphasis given to the use of maize as a model and representative species. With extensive references, Genetics, Biotechnology and Breeding of Maize and Sorghum will be immensely valuable to students and professional geneticists and breeders of cereals. ... Read more

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Although unpredictable and of short duration, periods of extreme environmental stress have been found to occur throughout the entire course of evolution. This book concentrates on the evolutionary changes that take place during these critical periods, when populations are driven to the extreme limits of resistance. Accumulating evidence suggests that it is precisely during such moments that fundamental changes in the natural order of systems are likely, both in terms of species extinctions and bursts of evolutionary activity.This study thus offers much potential for understanding the basic forces underlying the development of life on our planet. The book is necessarily multidisciplinary in approach, with an emphasis on the interaction between ecology, genetics, physiology, and the study of behavior and development.The book concludes with a discussion of the range expansion of species, and insightful observations regarding conservation strategies under rapidly changing conditions, including those created by environmental pollution. ... Read more

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Paperback. ICRP Publication 79 provides an extensive discussion of hereditary variations in the susceptibility to cancer, and includes a commentary on the possible implications of such susceptibility variations for radiological protection. Current ICRP recommendations are based essentially on the estimation of excess cancer risk after exposure of whole populations. Because of differences in genetic make-up between individuals, there is a strong expectation that the excess cancer risk per unit dose of radiation exposure will be non-uniform. The report seeks to review relevant data and make interim judgments on tumorigenic radiosensitivity in the genetic disorders of this type, and also on the likely contribution that genetic factors may make to radiation-induced cancer. Since directly informative epidemiological data on radiation effects under differing cancer predispositions are essentially lacking, emphasis is placed on experimental stu ... Read more

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This book an EXACT reproduction of the original book published before 1923. This IS NOT an OCR'd book with strange characters, introduced typographical errors, and jumbled words.This book may have occasional imperfections such as missing or blurred pages, poor pictures, errant marks, etc. that were either part of the original artifact, or were introduced by the scanning process. We believe this work is culturally important, and despite the imperfections, have elected to bring it back into print as part of our continuing commitment to the preservation of printed works worldwide. We appreciate your understanding of the imperfections in the preservation process, and hope you enjoy this valuable book. ... Read more

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A comprehensive guide to recommended strategies for controlling genetic and congenital disorders in Eastern Mediterranean countries. Addressed to policy-makers and service providers, the book aims to heighten awareness of these disorders while also increasing understanding of the interventions available for prevention and control. Although all major hereditary disorders are covered, particular attention is given to haemoglobin disorders, including thalassaemia and sickle cell disease, which are extremely common in these countries.

The book has fourteen chapters presented in four parts. Part one introduces the growing problem of genetic disorders, outlines options for treatment and prevention, and explains the principals of diagnosis. Current and future applications of genetic technology are also briefly discussed. Chapters in part two assess the epidemiological situation in Eastern Mediterranean countries for congenital malformation and chromosomal disorders, single gene disorders, and several common diseases, such as hypertension, diabetes, coronary heart disease, and some cancers that are now know to have a hereditary component. The genetic implications of consanguineous marriage, which remains common in some of these countries, are considered in particular detail.

Available approaches for prevention are described in part three. Separate chapters cover primary health care approaches, the use of family history and population screening to identify couples or families at risk, and the roles of counseling, prenatal diagnosis, and neonatal screening. Part four offers practical advice on policies and services for prevention.
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Deep-sea genetic resources and the interest of the biotechnology industry in their exploitation are emerging as a significant challenge for international oceans governance. This book is the first comprehensive examination of this issue and explores its relationship with marine scientific research and other activities in the deep sea. As well as a detailed survey of the state of industry interest in this new field of biotechnology it also sets out proposals for future sustainable management of these resources utilizing many existing international law and policy regimes. ... Read more

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The effects of genetic mutations on the mammalian skeleton are a useful aid in understanding how the skeleton develops. This book describes these effects, using the mouse as a primary source for considering the precartilaginous, cartilaginous, and bony skeletons, regional anatomy, and the interactions between genes and teratogens. The author summarizes the normal development of each part before discussing its mutations and completes his study by synthesizing the contributions mutants make to our understanding of the development of each part considered. ... Read more

Customer Reviews (3)

any reputable breeder should own and study this book.
Genetics of the dog


I breed quality toy poodles.

I believe any reputable breeder should own and study this book.

It is a starting place.You have to go beyond what is covered here.This will give you a good foundation in understanding the genetics of a dog.

I highly recommend this book for dog breeders of any breed, the author specializes in the German Sheppard, but this covers dogs in general.

GunnerMay, 2010

Very indepth
A highly complicated but essential book for the experienced & avid dog breeder. A wealth of knowledge in this one.

Truly useful in breeding, because it is readable.
This readable work gathers the research, theories and opinions of his predecessors and presents his own opinions as well, giving arguments on both sides. Sections on determination of coat color were especiallythoroughly done, relying heavily on Little's work, though differing sharplyon a couple of points. ... Read more