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In this edition of Clinics in Liver Disease, authors address the latest information on the epidemiology and natural history of HCV, with emphasis on mechanisms of viral persistence and fibrosis development. In addition, there is emphasis on new drugs in clinical trials as well as vaccines for HCC.The impact of HCV on transplantation is also addressed. ... Read more

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Webster's bibliographic and event-based timelines are comprehensive in scope, covering virtually all topics, geographic locations and people. They do so from a linguistic point of view, and in the case of this book, the focus is on "Hepatitis," including when used in literature (e.g. all authors that might have Hepatitis in their name). As such, this book represents the largest compilation of timeline events associated with Hepatitis when it is used in proper noun form. Webster's timelines cover bibliographic citations, patented inventions, as well as non-conventional and alternative meanings which capture ambiguities in usage. These furthermore cover all parts of speech (possessive, institutional usage, geographic usage) and contexts, including pop culture, the arts, social sciences (linguistics, history, geography, economics, sociology, political science), business, computer science, literature, law, medicine, psychology, mathematics, chemistry, physics, biology and other physical sciences. This "data dump" results in a comprehensive set of entries for a bibliographic and/or event-based timeline on the proper name Hepatitis, since editorial decisions to include or exclude events is purely a linguistic process. The resulting entries are used under license or with permission, used under "fair use" conditions, used in agreement with the original authors, or are in the public domain. ... Read more

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Univ. of Colorado, Denver. Reference on the diagnosis, treatment, and prevention of all currently known forms of viral hepatitis, A through E. For practitioners in internal medicine, family practice, or pediatrics. Previous edition: c1997. ... Read more

Product Description
Webster's bibliographic and event-based timelines are comprehensive in scope, covering virtually all topics, geographic locations and people. They do so from a linguistic point of view, and in the case of this book, the focus is on "Hepatitis," including when used in literature (e.g. all authors that might have Hepatitis in their name). As such, this book represents the largest compilation of timeline events associated with Hepatitis when it is used in proper noun form. Webster's timelines cover bibliographic citations, patented inventions, as well as non-conventional and alternative meanings which capture ambiguities in usage. These furthermore cover all parts of speech (possessive, institutional usage, geographic usage) and contexts, including pop culture, the arts, social sciences (linguistics, history, geography, economics, sociology, political science), business, computer science, literature, law, medicine, psychology, mathematics, chemistry, physics, biology and other physical sciences. This "data dump" results in a comprehensive set of entries for a bibliographic and/or event-based timeline on the proper name Hepatitis, since editorial decisions to include or exclude events is purely a linguistic process. The resulting entries are used under license or with permission, used under "fair use" conditions, used in agreement with the original authors, or are in the public domain. ... Read more

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Hepatitis B is a disease of the liver caused by the Hepatitis B virus (HBV), a member of the Hepadnavirus family and one of several unrelated viral species which cause viral hepatitis. It was originally known as "serum hepatitis" and has caused current epidemics in parts of Asia and Africa. Hepatitis B is recognised as endemic in China and various other parts of Asia. The proportion of the world's population currently infected with the virus is 3 to 6 per cent, but up to a third have been exposed. Symptoms of the acute illness caused by the virus include liver inflammation, vomiting, jaundice, and rarely, death. Chronic hepatitis B may cause liver cirrhosis which may then lead to liver cancer. This book presents the latest advances in the field. ... Read more

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In spite of the progress made in vaccine and antiviral therapy development, hepatitis B virus (HBV) infection still remains a major health care problem. Over 350 million people are chronically infected worldwide, showing differences in the severity of liver disease, clinical outcome and response to immune and antiviral-therapy. Parameters associated to the host immune system (HBV specific T and/or B-cell repertoires, defective antigen presentation and diminished Th1/Th2 response ratio) and viral factors, such as the HBV genotypes and their evolving variants, have largely contributed to the explanation of such differences. The unique genomic structure and replication cycle of HBV contribute to the occurrence of mutations in any of its genes undergoing selection pressures.The selection of one mutant over the others warrants a biological advantage to the prevalent mutation during the replication cycle of the virus or a selective advantage to the mutant over wild-type virus in host-virus interactions as the authors observed in Argentina where mutated HBsAg were detected, even in the presence of specific anti-HBs antibodies.Reports from USA, as well as from several European and Asian countries have focused on mutations within the HBV genome that may be associated with the hepatitis B vaccine and/or hepatitis B immune globulin (HBIG) failure, diagnostic escape mutants, antiviral therapy resistance, and differential outcomes in liver disease. In contrast, studies regarding these topics are almost lacking in Latin America. Within this context, it should be emphasised that the already known mutants circulating in other parts of the world could not necessarily be mirroring those strains circulating in this part of the American continent.Emerging data is filling the gap in our knowledge of HBV genotypes in several Latin American countries. While genotypes F and H of HBV are considered to be indigenous in this continent, genotypes A and D might be a mere reflection of a past European migration, and genotypes B and C could represent a consequence of a recent Asian migration. Few years ago, genotype G was detected in Mexico as previously identified in the USA and France.Unexpectedly, some strains ascribed to HBV genotype E (widely considered an African restricted genotype) have been observed in Argentina, even though genotypes F, A and D appear to be the most prevalent in this country. Co-circulation of all the already known genotypes and certain HBV variants in Latin America offers a unique opportunity to study basic viral and clinical features of this infection. ... Read more

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Japanese Red Cross, Tokyo. Proceedings of the International Symposium on Viral Hepatitis and Liver Disease: Molecules Today, More Cures Tomorrow, Tokyo, Japan, May 10-14, 1993. Basic science and clinical research. DNLM: Hepatitis, Viral, Human - diagnosis - congresses. ... Read more

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William Beaumont Hospital, Royal Oak, MI. Reference gives a comprehensive review of, and patient treatment manual for, chronic viral hepatitis. Accounts for subtleties in the diagnosis and treatment of individual patients. Organized in a case-study format. ... Read more