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Genetics and Tuberculosis Chairman: Douglas Young 1998 More people die each year from tuberculosis than from any other infectious disease, the annual death toll being almost three million (over 950f which are in developing countries) with eight million new cases being diagnosed every year. It is estimated that one-third of the world's population - nearly two billion people - is now infected, of which 5-10% will develop the disease. In 1993, the World Health Organization recognized tuberculosis as a 'global health emergency', the first time that a disease had ever been marked in this way. The emergence of drug-resistant forms of the disease combined with the paucity of new drugs makes the challenge of understanding and combating the disease especially urgent. This book explores the interplay between the Mycobacterium and its host by focusing on the research currently underway on the sequencing of the genome of Mycobacterium tuberculosis, and on the genetic and epidemiological studies of communities exposed to the disease (and on related animal models). From a synthesis of these data, new insights into the understanding of the pathogenesis, prevention and treatment of tuberculosis emerge. ... Read more

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Fevered Lives explores the changing meanings ofconsumption/tuberculosis in an extraordinarily readable culturalhistory. Emphasizing the material culture of disease, Ott traces theshift from the pre-industrial world of 1870, in which consumption wasconceived of primarily as a middle-class malaise that conferredvirtue, heightened spirituality, and gentility on the sufferer, to thepost-industrial world of today, in which tuberculosis is viewed as amicroscopic enemy, fought on an urban battleground and attackingprimarily the outcast poor and AIDS patients. ... Read more

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Historical perspectives on tuberculosis and public health
Ott interweaves the changing understanding and treatment of tuberculosis with its natural companion, public health.There are a variety of stories here--that of researchers like Edward Koch (who discovered the bacillus) and public health reformers like Charles Chapin and C-E. A. Winslow.The housing of consumptives, in such places as sanatoriums, merits a chapter, andmethods of nursing and care.Though the book is arranged thematically and not chronologiaclly, it is the story of our understanding of TB from the mid-19th century to the present.The book does not focus on the medical or scientific aspects of the disease, however (though they are mentioned) but rather, Ott's point seems to be that TB is not a definable illness by modern standards, but something that is changing continuously, as are our methods of dealing with the disease."Fevered Lives" offers some interesting perspectives on the history of public health and TB, and is a well written book on the history of medicine for those not in the profession. ... Read more

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Tuberculosis mortality in the United States and in Britain was declining in the late nineteenth century but rising in Ireland. Only in the first decade of the twentieth century did mortality from tuberculosis begin to fall and even then it remained higher in Ireland than in Britain and many other European nations throughout the first half of the twentieth century.

Why Ireland’s pattern of tuberculosis mortality was different is the subject of this book. Several controversies in the history of tuberculosis epidemics are addressed; the degree to which poverty and standard of living played a part in the tuberculosis decline, the role of public health, urbanisation and gender.

Because tuberculosis was comparatively higher in Ireland it remained a much more potent political issue well into the twentieth century and the interaction between Ireland’s politics and the question of tuberculosis is discussed. ... Read more

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Alaska Natives have struggled with the "white plague" of tuberculosis for centuries. At last, physician and historian Robert Fortuine brings their story to light. He provides a comprehensive account of tuberculosis from its earliest occurrence in prehistory through the latest outbreaks, made more threatening by HIV/AIDS. Fortuine describes the courage and self-sacrifice of itinerant nurses who endured challenging and often dangerous conditions, as well as the doctors who fought cuts in funding as valiantly as they battled for the lives of their patients.

Fortuine chronicles the heart-breaking removal of tuberculosis victims, many of them children, from their families and villages to hospitals in the Lower 48 states. He describes treatments, medical advances, and day-to-day life for the nurses, physicians, missionaries and teachers who worked to stem the tide that killed and disabled thousands. The struggle against tuberculosis in Alaska is a story of triumph against untold suffering and crippling odds, but it is also a cautionary tale, as villages experience the re-emergence of an increasingly resistant disease in the twenty-first century.

"Must We All Die?" is a timely and encyclopedic contribution to the history of medicine. Historians and health care professionals will hail the volume as a classic. The book is also a tribute to all of those who fought tuberculosis and to the Alaska Natives who endured a cruel disease that destroyed families and ravaged villages. ... Read more

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Everything you ever wanted to know about TB and more
This book is a compilation of chapters written by different experts about various issues in dealing with TB.It's not meant for light reading about an ugly subject, but it's still a good jumping off point for anyone who's studying this dreadful disease. ... Read more

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In the 1980s and early 1990s, New York City experienced an unprecedented outbreak of tuberculosis. Inadequate healthcare services, an increase in social alienation of the poor, and the emergence of drug-resistant strains led city health officials to respond with draconian policies to ensure compliance, including the use of detention of noninfectious individuals-sometimes for up to two years-that violated individual civil liberties. The New York TB epidemic has since been controlled, but this public health triumph has come at great cost. This gripping narrative of medicine and morality raises ethical issues that are of increasing importance in the world of modern medicine. Richard J. Coker warns the international community against assuming a fortress mentality, advocating a more just balance between health, liberty, and the burdens society should be prepared to accept in the pursuit of both. ... Read more

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Throughout history, tuberculosis has been at or near the top of the list of infectious diseases that have plagued humankind. This pervasive disease has had a central position not only in causing illness but also in challenging medical scientists to understand it - and, in so doing, to further understand all of human health and illness. Pioneers in Medicine and Their Impact on Tuberculosis tells the stories of six of these individuals: Rene Theophile Hyacinthe Laennec (pathology), Heinrich Hermann Robert Koch (bacteriology), Hermann Michael Biggs (public health), Clemens von Pirquet (immunology), Wade Hampton Frost (epidemiology), and Selman Abraham Waksman (antibiotics). It examines not only their contributions in their own fields but also their special work in conquering tuberculosis. Presenting their fascinating lives and the seminal work they did in their disciplines, the author examines the importance of their discoveries and relates them to the dramatic expansion of medical science during the era in which they lived. ... Read more

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The Tuberculosis Movement presents a detailed description of the evolution of the American tuberculosis movement from its inception in the late 19th century to its maturity in 1917. As Teller demonstrates, the tuberculosis movement during this era pioneered many of the methods of contemporary public health--the voluntary association dedicated to eradicating a specific disease, close cooperation between physicians and laity and between public and private agencies, and campaigns of mass public education. The most comprehensive study of the movement to date, this book contains a wealth of information not found in any other history of the campaign against tuberculosis, including full accounts of the backgrounds, motivations, and ideology of the movement's leadership; the origins and activities of the state and local associations and their cooperation with other groups in the fight to control the disease; the educational campaign mounted by the movement's leadership; and public health measures and institutions established to restrict the spread of the disease. ... Read more

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An adequate strategy for the control of tuberculosis (TB) globally calls for a comprehensive approach to address all of the main constraints facing TB control, including emerging challenges, as well as the main risk factors influencing the incidence of TB and socioeconomic and environmental aspects. The purpose of this handbook is to bring together in summarized form the issues, recommended strategies and practical measures involved in addressing each of the components of the Stop TB Strategy.

The handbook has been prepared principally for use by national TB control program managers and staff, as well as partner organizations and professionals involved in implementing TB control activities. Readers are provided with a concise account of the essential elements of a comprehensive TB control program and an overview of the full range of activities that need to be implemented to achieve the TB control targets set for 2015. This publication is the successor to the WHO Tuberculosis Handbook published in 1998. ... Read more

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Craig-y-nos Castle, on the edge of the Brecon Beacons in South Wales, was the home of the world famous opera singer, Adelina Patti. After her death in 1919, it became a tuberculosis sanatorium, mainly for children and young adults. The 'Children of Craig-y-nos' project was begun in 2006 by Ann Shaw who had spent four years there from the age of nine to thirteen. The launch of her blog (www.craig-y-nos.blogspot.com) to collect the memories of ex-patients and staff was so successful that within a year over a hundred stories and 1200 photographs, mostly taken by the children themselves, had been contributed. There followed three photographic exhibitions, radio programmes, a reunion at Craig-y-nos Castle, and a Lottery grant to produce this book. But despite a romantic location, this is not a fairy tale. TB affected the whole community - physically, socially and emotionally. It was the disease never spoken about except in hushed whispers. Craig-y-nos was called a hospital but it had all the hallmarks of a prison for sick children. Even at a distance of fifty or sixty years, some people broke down when reliving deeply buried memories. Others were unable to talk at all but communicated entirely though e.mail. A few remember physical and sexual abuse by staff. Stomach wash-outs terrified toddlers. Use of restraint by tying children to cot and bed railings was justified by over-stretched staff but criticized by hospital inspectors. Even keeping five-year-olds in high-sided cots could be interpreted as a form of imprisonment. The physical isolation of Craig-y-nos was another. Only one young woman admits to successful escape although several teenagers and children made abortive bids for freedom. Although this is an historical study, TB is not a disease of history. The World Health Organization in 1993 declared TB a public health emergency. An estimated 8.8 million people were diagnosed with TB in 2005 and 1.6 million died of it. But however difficult it becomes to control tuberculosis both locally and globally, one thing is certain. Those infected will never again be isolated from the rest of society because history has shown that policing infectious diseases is neither workable nor humane.Ann Shaw was born in Crickhowell, Powys, and worked as a journalist on newspapers in London, Lancashire, Yorkshire and Edinburgh before joining the Glasgow Herald as a Feature Writer. In 1997, she enrolled as a mature student at Glasgow School of Art in order to fulfil a lifelong ambition to be an artist. She now lives in Bridge-of-Allan, Scotland.Carole Reeves is the Outreach Historian, Wellcome Trust Centre for the History of Medicine, University College London. She develops projects designed to further public interest in the history of medicine, and helps others to do so. ... Read more

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An Historical Chronology of Tuberculosis
An illustrated chronicle of tuberculosis briefly and interestingly told in this up-to-date second edition:

Ancient Period (5000 B.C. -- 1600 A.D.)
Pre-Modern Period (1600 -- 1800)
Modern Period I (1800 -- 1881)
Modern Period II (1882 -- Now)

The modern period is divided into two parts: the years before and after Koch's discovery of the tubercle bacillus in 1882

Because the development of our knowledge of tuberculosis closely follows the path of medical progress, periods and some pertinent discoveries in general medical history are included along with a few background items in world history.

About 500 discoveries and events pertaining directly to the history of tuberculosis are given along with their references. This makes available the first selected bibliography embracing the entire subject and is a valuable addition to the book. (The first edition did not have a bibliography).

The book should be of special interest to workers in tuberculosis and public health, particularly, doctors, nurses, social workers, and educators. Tuberculosis patients will find it of interest. As a reference book it should prove to be of value to many physicians and others in the medical sciences.

The purpose of the book is to make readily avialable the significant discoveries and events in the history of tuberculosis along with appropriate references.
--- from book's dustjacket ... Read more

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A Truly Personal Account that will raise awarenesss worldwide of Tuberculosis and Multidrug-Resistant Tuberculosis. The Tuberculosis Survival Handbook is an engrossing personal story as well as an invaluable source of information for people with TB around the world.

In recognition of the worldwide TB epidemic, this useful publication has been extensively updated. The comprehensive and easily readable text covers the clinician’s and patient’s perspective; practical information including the DOT strategy for adherence to treatment; treatment and management. A must read for patients and healthcare workers. ... Read more

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This scarce antiquarian book is a selection from Kessinger Publishing's Legacy Reprint Series. Due to its age, it may contain imperfections such as marks, notations, marginalia and flawed pages. Because we believe this work is culturally important, we have made it available as part of our commitment to protecting, preserving, and promoting the world's literature. Kessinger Publishing is the place to find hundreds of thousands of rare and hard-to-find books with something of interest for everyone! ... Read more

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Extracted From The Bulletin University Of New Mexico. ... Read more

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This is an EXACT reproduction of a book published before 1923. This IS NOT an OCR'd book with strange characters, introduced typographical errors, and jumbled words.This book may have occasional imperfections such as missing or blurred pages, poor pictures, errant marks, etc. that were either part of the original artifact, or were introduced by the scanning process. We believe this work is culturally important, and despite the imperfections, have elected to bring it back into print as part of our continuing commitment to the preservation of printed works worldwide. We appreciate your understanding of the imperfections in the preservation process, and hope you enjoy this valuable book. ... Read more

Product Description
This is an EXACT reproduction of a book published before 1923. This IS NOT an OCR'd book with strange characters, introduced typographical errors, and jumbled words.This book may have occasional imperfections such as missing or blurred pages, poor pictures, errant marks, etc. that were either part of the original artifact, or were introduced by the scanning process. We believe this work is culturally important, and despite the imperfections, have elected to bring it back into print as part of our continuing commitment to the preservation of printed works worldwide. We appreciate your understanding of the imperfections in the preservation process, and hope you enjoy this valuable book. ... Read more