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$44.90
21. The Computational Neurobiology
$27.94
22. Neurobiology of Addictions: Implications
$92.70
23. Foundations of Neurobiology: with
$44.66
24. Behavioral Neurobiology: An Integrative
$126.51
25. Glial Neurobiology
$53.65
26. Integrative Action of the Autonomic
$111.41
27. The Neurobiology of Pain (Molecular
$149.95
28. Catatonia in Autism Spectrum Disorders,
$43.62
29. Alcohol Problems in Adolescents
$174.84
30. The Neurobiology of Criminal Behavior
$35.00
31. The Neurobiology of Learning:
 
$4.99
32. The Neurobiology of Depression
$14.39
33. An Introduction to Molecular Neurobiology
$29.95
34. Being a Brain-Wise Therapist:
$126.00
35. Advances in Vagal Afferent Neurobiology
$21.00
36. Brain and Culture: Neurobiology,
$8.29
37. Molecular Neurobiology for the
 
$74.95
38. THE NEUROBIOLOGY OF LEARNING AND
$169.00
39. The Role of Microtubules in Cell
$25.95
40. The Integrative Neurobiology of

21. The Computational Neurobiology of Reaching and Pointing: A Foundation for Motor Learning (Computational Neuroscience)
by Reza Shadmehr, Steven P. Wise
Hardcover: 595 Pages (2005-01-01)
list price: US$68.00 -- used & new: US$44.90
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Asin: 0262195089
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Book Description
Neuroscience involves the study of the nervous system, and its topics range from genetics to inferential reasoning. At its heart, however, lies a search for understanding how the environment affects the nervous system and how the nervous system, in turn, empowers us to interact with and alter our environment. This empowerment requires motor learning. The Computational Neurobiology of Reaching and Pointing addresses the neural mechanisms of one important form of motor learning. The authors integrate material from the computational, behavioral, and neural sciences of motor control that is not available in any other single source. The result is a unified, comprehensive model of reaching and pointing. The book is intended to be used as a text by graduate students in both neuroscience and bioengineering and as a reference source by experts in neuroscience, robotics, and other disciplines.

The book begins with an overview of the evolution, anatomy, and physiology of the motor system, including the mechanisms for generating force and maintaining limb stability. The sections that follow, "Computing Locations and Displacements," "Skills, Adaptations, and Trajectories," and "Predictions, Decisions, and Flexibility," present a theory of sensorially guided reaching and pointing that evolves organically based on computational principles rather than a traditional structure-by-structure approach. The book also includes five appendixes that provide brief refreshers on fundamentals of biology, mathematics, physics, and neurophysiology, as well as a glossary of relevant terms. The authors have also made supplemental materials available on the Internet. These web documents provide source code for simulations, step-by-step derivations of certain mathematical formulations, and expanded explanations of some concepts. ... Read more


22. Neurobiology of Addictions: Implications for Clinical Practice
Hardcover: 119 Pages (2002-04-24)
list price: US$42.00 -- used & new: US$27.94
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Asin: 0789016664
Average Customer Review: 4.0 out of 5 stars
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Book Description
Bridge the gap between the physical foundations of substance abuse and the psychosocial approaches that can treat it!

This groundbreaking book offers helping professionals a thorough introduction to the neurobiological aspects of substance abuse. It presents the basic information on the subject, including the various neurobiological theories of addiction, and places them in a psychosocial context. Its clear and straightforward style connects the theoretical information with practical applications. This is an essential resource for substance abuse counselors, researchers, therapists, and social workers.

Neurobiology of Addictions offers sound, tested information on substance abuse issues, including:

  • neurobiological theories of addiction
  • integrating drug treatments and therapeutic interventions
  • using neurobiology to discover substance abuse in clients of various ages
  • perspectives from social work, pharmacology, biology, and neuroscience
... Read more

Customer Reviews (1)

4-0 out of 5 stars Neurobiology for non-medical professionals
This book discusses the effects of substance of abuse on brain chemistry. It is of interest to anyone treating addictions. It is not a "quick read" for people without a basic grounding in neurobiology, but with persistance, you will learn. ... Read more


23. Foundations of Neurobiology: with Student CD-ROM
by Fred Delcomyn
Hardcover: 592 Pages (1998-02-15)
list price: US$115.95 -- used & new: US$92.70
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Asin: 0716732955
Average Customer Review: 4.5 out of 5 stars
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Customer Reviews (3)

4-0 out of 5 stars Needs more Diagrams
The book is very informative and fairly easy to understand with a basic background in neurobiology.It has a lot of actual photographs of equiptment/neurons and cell images.However, there are not a lot of the colorful animated diagrams you typically see in molecular biology books.I think that this makes certain concepts more difficult to understand, thus the 4 star rating.This is my only complaint with this product.

5-0 out of 5 stars Foundations of Neurobiology
Great purchase. Arrived in great condition and delivered well within the designated time.

4-0 out of 5 stars Basic principles nicely presented but depth is missing
Foundations of Neurobiology presents things reallyclearly, is easy toread and makes things easy to understand. Foundations of Neurobiology isreally excellent book for those high school students andother interestedindividuals with no background in biological sciences who would like tolearn something about neurobiology. There are some pictures whereexplanations have slipt to wrong places but this cannot be expected toconfuse readers too much, for things are stated correctly and very clearlyin text. It could be said that this book gives quite comprehensive glanceat foundations of neurobiology. However, I would not recommendateFoundations of Neurobiology for students who have taken basic biologycourses in university and who are thus at least to some extend familiarwith basic ideas about membrane proteins, migration of cells, chemotaxis,sensory systems, growth factors, membrane potential, cellular signalingetc. Or, to be more precise, I would not recommendate this book for use asan _only_ textbook but if you are reading on nice-to-know basis only or asa lead and repetition to understand other, more thorough books, this isreally the book for you. For some parts it lacks the depth that is neededin university neurobiology courses e.g. on the part of the molecular levelof axon guidance, and neuronal movement and development nervous system arepractically not discussed at all. This should of course be expected, for inthe back of the book it is stated that "Foundations of Neurobiologyallows students with only a background in general biology the chance toexplore this vibrant science." (General biology should be interpretedas "with little knowledge about basics of modern biology includingcell biology, structural biology, molecular biology andbiochemistry".)Well, it's a fine book, though I personallywould have liked more detailed information. But that's just my perversemind and thus four stars is the grade for Delcomyn's Foundations ofNeurobiology. ... Read more


24. Behavioral Neurobiology: An Integrative Approach (Psychology)
by Gunther K. H. Zupanc
Paperback: 360 Pages (2004-01-29)
list price: US$49.95 -- used & new: US$44.66
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Asin: 0198700563
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Book Description
Animals often exhibit intriguing and captivating patterns of behavior, from migration and homing, to communication. But how is this behavior controlled? This new textbook introduces undergraduate students and other readers to the fascinating field of neuroethology - the study of the neurobiological processes underlying animal behavior. Written in a lively, easy to read style, and assuming no background knowledge of animal behavior or neurobiology, this book introduces the key concepts and ideas which underpin the subject, and describes many of the key findings that have helped us to understand this intricate and elegant subject.Beginning with a look at the history of the study of behavior, from Aristotle to recent breakthroughs and predictions for the future, the book then reviews the ethological and neurobiological concepts that constitute the essential tools of behavioral neurobiology, before moving on to the field of neuroethology itself. In each chapter, the text not only describes the major findings in each area, but also describes the approaches used to obtain these results. Many chapters contain a detailed case study describing the research perfomed. A key feature of the text is the number of excellent learning aids included. Each chapter ends with a summary of key points, exercises and suggestions for further reading. Boxes are used both to provide relevant physical and chemical background information and to add additional historical interest by describing the life and work of eminent neuroethologists. ... Read more


25. Glial Neurobiology
by Alexei Verkhratsky, Arthur Butt
Hardcover: 230 Pages (2007-09-17)
list price: US$170.00 -- used & new: US$126.51
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Asin: 0470015640
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Book Description
AT LAST - A comprehensive, accessible textbook on glial neurobiology!

Glial cells are the most numerous cells in the human brain but for many years have attracted little scientific attention. Neurophysiologists concentrated their research efforts instead, on neurones and neuronal networks because it was thought that they were the key elements responsible for higher brain function. Recent advances, however, indicate this isn’t exactly the case. Not only are astroglial cells the stem elements from which neurones are born, but they also control the development, functional activity and death of neuronal circuits. These ground-breaking developments have revolutionized our understanding of the human brain and the complex interrelationship of glial and neuronal networks in health and disease.

Authored by leading experts in the field, Glial Neurobiology  provides a concise, authoritative introduction to glial physiology and pathology.

The book presents all major types of glial pathology; topics include: the morphology and interrelationships between glial cells and neurones in different parts of the nervous system; intra and inter cellular signaling in glial networks; the role of glial cells in synaptic plasticity, neuronal survival and development of nervous system; cellular and molecular mechanisms of metabolic neuronal-glial interactions; and the role of glia in nervous system pathology.

  • Profoundly illustrated with figures, including unique images from the authors’ own libraries of images
  • Includes numerous text boxes to highlight and summarize key facts
  • Features an associated website

This textbook is invaluable to undergraduate and postgraduate neuroscience, biomedical, medical, pharmacy, pharmacology, neurology, neurosurgery, and physiology students. Furthermore, this title is of interest to professionals and researchers in neuroscience, physiology, pharmacology and pharmaceutics. ... Read more


26. Integrative Action of the Autonomic Nervous System: Neurobiology of Homeostasis
by Wilfrid Jänig
Hardcover: 632 Pages (2006-07-24)
list price: US$175.00 -- used & new: US$53.65
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Asin: 0521845181
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Book Description
Almost all bodily functions are dependent on the functioning of the autonomic nervous system - from the cardiovascular system, the gastrointestinal tract, the evacuative and sexual organs, to the regulation of temperature, metabolism and tissue defence. Balanced functioning of this system is an important basis of our life and well-being. This book gives a detailed description of the cellular and integrative organisation of the autonomic nervous system, covering both peripheral and central aspects. It brings to light modern neurobiological concepts that allow understanding of why the healthy system runs so smoothly and why its deterioration has such disastrous consequences. This academic reference volume will appeal to advanced undergraduate and graduate students studying the neurobiology of the autonomic nervous system within the various biological and medical sciences and will give access to ideas propagated in psychosomatic and alternative medicines. ... Read more


27. The Neurobiology of Pain (Molecular and Cellular Neurobiology)
Hardcover: 416 Pages (2005-11-10)
list price: US$135.00 -- used & new: US$111.41
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Asin: 0198515618
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Book Description
The last decade has seen major advances in the neurobiology of pain, primarily resulting from a deeper understanding of the way in which pain signals are coded and processed in the nervous system. This volume in the Molecular and Cellular Neurobiology seriesis the first book for many years to present anintegrated overview of the current state of research intothe neurobiology of chronic and acute pain.While recent molecular aspects of nociception are covered in some detail, the book also emphasises the importance of viewing the pain experience as the co-ordinated response of many different areas of the nervous system. The molecular advances are set in the context of the neurobiological system of pain processing. The appropriate behavioural response to injury can therefore be thought of as the result of the integration of information processed within areas of the brain concerned with cognition, affect, sensory discrimination and movement.Chapters cover recent advances in nociceptor transduction mechanisms, nociceptor plasticity and the biochemical anatomy of pain pathways. Other contributions are concerned with the development of pain systems and with the central processing of nociceptive information studied with brain imaging techniques. Several chapters additionally cover the mechanisms of clinically important pain states such as neuropathic pain, cancer related pain and migraine.This volume presents a state-of-the-art account of the neurobiological basis of pain, edited and written by the leading scientists in this field. ... Read more


28. Catatonia in Autism Spectrum Disorders, Volume 72 (International Review of Neurobiology)
by Dirk Marcel Dhossche
Hardcover: 336 Pages (2006-03-07)
list price: US$149.95 -- used & new: US$149.95
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Asin: 0123668735
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Editorial Review

Book Description
The study of catatonia in Autism Spectrum Disorders is a novel and controversial topic. Catatonia is a motor disorder characterized by stereotypy, rigidity, mutism, and posturing. These motor signs are also characteristic of autism. The interest in the relation between autism and catatonia stems from clinical observations that autistic and catatonic symptoms overlap, that some people with autism develop full-blown catatonia, and that anti-catatonic treatments bring relief in some of those patients.
This book explores the question of if the two syndromes have a common pathophysiology. It also examines whether the successful treatment of catatonia be applied to patients with both autism and catatonia. The book concludes with blueprints for the assessment, treatment, and future study of catatonia in Autism Spectrum Disorders. These blueprints aim to increase early recognition and treatment of catatonia in patients with autism, show the urgency of controlled treatment trials and increased collaborative and interdisciplinary research into the co-occurrence of these two enigmatic disorders.

* Provides a historical perspective of the concepts of catatonia and autism, as described by old European masters like Bleuler and Kalhbaum
* Presents clinical-epidemiological studies that apply systematic criteria of catatonia in populations with Autism Spectrum Disorders
* Includes a review of the importance of psychomotor function for normal and abnormal development ... Read more


29. Alcohol Problems in Adolescents and Young Adults: Epidemiology. Neurobiology. Prevention. and Treatment (Recent Developments in Alcoholism)
Paperback: 456 Pages (2005-11-15)
list price: US$49.95 -- used & new: US$43.62
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Asin: 0387292152
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Book Description

Alcohol continues to be the substance of choice for todays youth, leading to serious physical, psychological, and social consequences. Alcohol Problems in Adolescents and Young Adults ably addresses this growing trend. The latest entry in the Recent Developments in Alcoholism series, it comprehensively presents a wide-ranging clinical picture of teen drinking - epidemiology, neurobiology, behavioral phenomena, diagnostic and assessment issues, prevention and treatment data - in a developmental context. Fifty expert contributors display the scientific rigor, practical wisdom, and nuanced analysis that readers have come to expect from previous volumes.

Among the subjects studied in depth:

- Initiation of alcohol use/abuse

- Risk and protective factors for alcohol dependence

- High-risk adolescent populations

- Drinking habits of college students

- Long-range consequences of teenage drinking

- Family-, school-, and community-based prevention programs

- Treatment of comorbid substance and psychiatric disorders

Clinicians, researchers, and policy makers will find this a bedrock source of evidence-based knowledge, whether ones goal is choosing an age-appropriate assessment tool for eighth graders, preventing drinking among high school students, or understanding the alcohol-friendliness of campus culture. Here is a critical resource for all professionals dedicated to helping youngsters grow up sober.

... Read more

30. The Neurobiology of Criminal Behavior (Neurobiological Foundation of Aberrant Behaviors)
Hardcover: 304 Pages (2002-06-15)
list price: US$175.00 -- used & new: US$174.84
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Asin: 0792376749
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Book Description
Criminological theory dating back one hundred years has beenaware of the need to develop a neurobiology of extroversion,impulsivity, frontal-lobe dysfunction, and aggressive behavior, yet inthe twentieth century criminologists have largely forsaken thispsychobiological legacy.
The Neurobiology of Criminal Behavior looks at this legacy withreference to a variety of neurobiological methodologies currently invogue. The authors are all distinguished researchers who havecontributed considerably to their respective fields of psychiatry,psychology, psychobiology, and neuroscience. ... Read more


31. The Neurobiology of Learning: Perspectives from Second Language Acquisition
by John H. Schumann, Sheila E. Crowell, Nancy E. Jones, Namhee Lee, Sara Ann Schuchert, Lee Alexandra Wood
Paperback: 232 Pages (2004-01)
list price: US$44.95 -- used & new: US$35.00
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Asin: 0805861416
Average Customer Review: 4.0 out of 5 stars
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Book Description
This book constitutes a timely contribution to the existing literature by presenting a relatively comprehensive, neurobiological account of certain aspects of second language acquisition. It represents the collaborative efforts of members of the Neurobiology of Language Research Group in the Applied Linguistics and TESL Department at UCLA. Members of the group are trained in neurobiology and then use this knowledge to develop biological accounts of various aspects of applied linguistics.

The volume avoids the corticocentric bias that characterizes many brain-language publications--both cortical and subcortical structures receive their appropriate attention. In addition, it demonstrates that enough is presently known about the brain to inform our conceptualizations of how humans acquire second languages, thus, it provides a refreshingly novel, highly integrative contribution to the (second) language acquisition literature.

The goal of the research program was based on the need to drawmore links between the neurobiological mechanisms and second language acquisition. As such, the book promotes a neurobiology of language that starts with the brain and moves to behavior. The fundamental insights presented should guide second language acquisition researchers for years to come.
... Read more

Customer Reviews (2)

5-0 out of 5 stars out standing text
The authors provide a remarkable clear explanation of the executive and attentional control systems from a global brain paradigm.Inadvertently explaining ADHD with up-to-date neurobiological science, the acquisition of a second language has many parallels to AHDH.The book leave's aside the out-dated neuroscience of "attention, impulsivity, and hyperactivity" for newer and more accurate data in explaining ADHD biology.SLA also matches the learning of compensatory strategies used in treating ADHD and other similar impairments.

3-0 out of 5 stars Great subject, not so great research
This is a fantastic subject to write a book about.Unfortunately, much of the research it uses is out of date and no longer applies.It also is very one-sided.The authors seem to have formed their own conclusions and found research to support them, without taking into consideration all the research that contradicts these conclusions. This wouldn't be such a bad thing if it weren't that they are stating these conclusions as fact instead of point of view.

This is still a reasonably decent reference as it's difficult to find such a broad collection of research on this one narrow subject.It's just very misleading to any reader who has not done any previous studying of neurobiology. ... Read more


32. The Neurobiology of Depression : A Scientific American article
by Charles B. Nemeroff
 Digital: Pages (2002-05-01)
list price: US$4.99 -- used & new: US$4.99
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Asin: B00006BNO0
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Download Description
The search for biological underpinnings of depression is intensifying.Emerging findings promise to yield better therapies for a disorder that too often proves fatal. ... Read more


33. An Introduction to Molecular Neurobiology
by Zach W. Hall
Hardcover: 530 Pages (1992-02)
list price: US$76.95 -- used & new: US$14.39
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Asin: 0878933077
Average Customer Review: 5.0 out of 5 stars
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Customer Reviews (1)

5-0 out of 5 stars This is an excellent book
This book is simply complete, adequate, and extremely well written concerning the subject of neurobiology. An updated version is eagerly awaited. ... Read more


34. Being a Brain-Wise Therapist: A Practical Guide to Interpersonal Neurobiology
by Bonnie Badenoch
Paperback: 380 Pages (2008-06-30)
list price: US$29.95 -- used & new: US$29.95
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Asin: 0393705544
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Book Description
Linking the science of interpersonal neurobiology to the art of therapy.

This book translates current advances in neuroscience into useful clinical applications for the practitioner. Linking science with clinical material, the author persuasively argues for more scientifically based long-term psychotherapy. Written for couples therapists, family therapists, and those working with individuals, it effectively brings neuroscience to the on-the-ground counselor. ... Read more


35. Advances in Vagal Afferent Neurobiology (Frontiers in Neuroscience (Boca Raton, Fla.).)
Hardcover: 544 Pages (2005-06-01)
list price: US$159.95 -- used & new: US$126.00
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Asin: 084932131X
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Editorial Review

Book Description
Vagus is a Latin word that shares its root with the word vague. This is appropriate, as much of what we know about vagal sensory neuroscience remains vague and imprecise. The number of scientific studies aimed directly at investigating afferent nerves within the vagi pale in comparison with those involved within the spinal afferent system. In addition, because the vagus meanders through the viscera, providing regulatory influences over the thoracic and abdominal organs, experts in vagal neurobiology are typically organo-centric and spread across many disciplines.Advances in Vagal Afferent Neurobiology brings together more than thirty of the world's leading neuroscientists to present a coherent summary of vagal afferent neuroscience obtained within the body's organ systems. By juxtaposing the contributions of many disciplines in a single volume, this work encourages a cross-fertilization of ideas that provides new insights and increased focus on this important topic. The book contains chapters that deal with vagal nerves in the central nervous system, lungs, esophagus, heart, and gastrointestinal tract. It also covers critical aspects ranging from vagus nerves in the embryo to vagus nerves in the adult, and considers activity in individual neurons to whole animal studies of the reflexes and sensations such activity engenders.Each chapter provides an overview of a particular area of vagal afferent neuroscience, and, in many cases, offers details pertaining to specific experiments and techniques. By painting vagal afferent biology with the broadest brush possible, this text offers a unique and useful resource for the student, as well as for the established neuroscientist interested in the visceral nervous system. ... Read more


36. Brain and Culture: Neurobiology, Ideology, and Social Change (Bradford Books)
by Bruce E. Wexler
Hardcover: 319 Pages (2006-05-05)
list price: US$34.00 -- used & new: US$21.00
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Asin: 0262232480
Average Customer Review: 4.5 out of 5 stars
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Book Description
Research shows that between birth and early adulthood the brain requires sensory stimulation to develop physically. The nature of the stimulation shapes the connections among neurons that create the neuronal networks necessary for thought and behavior. By changing the cultural environment, each generation shapes the brains of the next. By early adulthood, the neuroplasticity of the brain is greatly reduced, and this leads to a fundamental shift in the relationship between the individual and the environment: during the first part of life, the brain and mind shape themselves to the major recurring features of their environment; by early adulthood, the individual attempts to make the environment conform to the established internal structures of the brain and mind. In Brain and Culture, Bruce Wexler explores the social implications of the close and changing neurobiological relationship between the individual and the environment, with particular attention to the difficulties individuals face in adulthood when the environment changes beyond their ability to maintain the fit between existing internal structure and external reality. These difficulties are evident in bereavement, the meeting of different cultures, the experience of immigrants (in which children of immigrant families are more successful than their parents at the necessary internal transformations), and the phenomenon of interethnic violence. Integrating recent neurobiological research with major experimental findings in cognitive and developmental psychology--with illuminating references to psychoanalysis, literature, anthropology, history, and politics--Wexler presents a wealth of detail to support his arguments. The groundbreaking connections he makes allow for reconceptualization of the effect of cultural change on the brain and provide a new biological base from which to consider such social issues as "culture wars" and ethnic violence. ... Read more

Customer Reviews (2)

5-0 out of 5 stars Courageous Insights Relevant to Every One of Us
The study of psychology has traveled down some interesting roads during the last century. After the long flirtation with the fascinating but flawed theories of psychoanalysis, a dominant theme became the idea that humans were no more than programmable robots. By way of a dozen detours, we then arrived at a new type of robot, one that was pre-programmed by his or her genes with environment contributing a little or a lot, depending upon our own beliefs about human nature. For that was always one of the problems: beliefs, biases and politics all played with the findings of psychology and neurology. For the totalitarian state, the idea that all people are born biologically equal and that, with the right prodding, they could be guided to be good citizens, became an article of faith in some parts of the world. Research, often only half understood, lead to grotesque attempts at social engineering.

Now the pendulum has swung again. Genes do not so much determine our behavior but influence our responses to the environment. During childhood our brains are incredibly plastic. The developing brain requires the right mix of nutrients, sensory, emotional and intellectual stimulation to realize its potential. The lion's share of higher cortical functions are dedicated to social functioning, and children first learn to develop in order to learn the social rules that help them to conform. During adolescence and early adulthood, this conformity is usually replaced by increasing individuality and drives to leave the parental nest. This leads to gradual attempts to shape the environment to fit with the structure of his or her brain and mind. Yet some plasticity remains throughout life, and we are likely able to create new neural connections and even new neurons into old age. And these new neurons and connections develop not only in response to the external environment, but also in response to our thoughts and emotions.

To these three findings - that genes predispose but do not determine; that our brains are malleable and plastic throughout life and third, the impact of our thoughts and beliefs on our brains - we can now add a fourth: the interplay of culture and society on our minds and genes, and the effects of our minds and genes on society.

This is one of a number of recent books that has begun to explore these important themes. Our genes lead - but do not force - us to create our world, and the world that we create has a powerful impact on the development of the next generation, who in turn create the world in their image.

Bruce Wexler is a Professor of Psychiatry at Yale and also directs the Neurocognitive Research Laboratory at the Connecticut Mental Health Center. He has been known for years as one of the most original and creative thinkers in his field. It shows in this book. It is just over 300 small pages and is crammed full of interesting ideas. The book is divided into two sections and five chapters:

Section I: Background: Some Basic Facts about the Human Brain
I. Transgenerational Shaping of Human Brain Function
2. Effects of Sensory Deprivation and Sensory Enrichment on Brain Structure and Function
3. Effects of the Social Environment on Brain Structure and Function

Section II. The Neurobiology of Ideology
4. Self-Preservation and the Difficulty of Change in Adulthood
5. The Meeting of Cultures
After which there is an Epilogue, References and an Index.

Bruce offers a neurologically based hypothesis that may go some way toward explaining some of the sectarian strife that has plagued so much of the world throughout history. He talks about the "neurobiology of ideology," to capture the process by which the human brain molds itself to its environment. Input from the world around us helps fashion our brains, and we in turn shape the world around us, which again shapes and changes the brain, leading to an endless dance between the brain, the mind and society.

This model helps to explain why it is that early life experiences can make it difficult to deal with unfamiliar events, emotions and situations later in life. But the argument also has a small hole in it. The author is an expert in human pathology, so he is interested in the way in which, say, "programming" in childhood may create problems later in life, as the individual encounters new challenges for which he or she is not prepared. As an example, if we think about an individual who was abused in childhood, he or she may have problems accepting and trusting a loving relationship as an adult. The disparity between the new environment and the developed brain may become a potent cause of distress and dysfunction. But that fails to answer another question: why do some people and some societies become distressed by novelty, while others delight in it?

This is an important, fascinating and thought provoking book that may provide answers to some of the problems that we see around us. We just need two more things: proof of his hypotheses and a way of using the model. That being said this work is already changing the way in which we see ourselves, not as the victims or beneficiaries of our genes, but as participants and co-creators of society and ourselves.

Highly recommended.

4-0 out of 5 stars How do we overcome childhood inculcation?
I purchased Wexler's new book to further my understanding of the process thru which a person sheds obsolete religious beliefs -- such as those that were inculcated in childhood -- and then adapts present-day, non-theistic beliefs such as those described in my book "Concepts: A ProtoTheist Quest for Science-Minded Skeptics." I was hoping for a neurobiological elaboration of MD Faber's "The Psychological Roots of Religious Belief" (see my Amazon review of it) but I was only partially gratified.

After a brief description of the human brain, Wexler distinguishes two phases in the development of a person's brain (in my words, not his): In childhood the `seedling' neurons are searching out stimuli that `feed' their growth; what they obtain is how their brain gets `wired' ("our brain is what it eats"). As adults, this `wiring' not only influences what their brain looks for (gestalt) but how it interprets what it finds (projection); we try to reinforce what we learned as children and to adapt our environment to conform to our expectations. What doesn't conform to our mindset is routinely ignored or rejected. So as adults, one has to very deliberately maintain an open-mind to consider ideas that don't conform to one's early mindset, and the more the ideas stretch our mindset, the greater our tendency to reject them. Wexler elaborates extensively on this process citing research to back-up his contentions and examples of the consequences.

What Wexler doesn't elaborate to my satisfaction is how one overcomes the beliefs inculcated in childhood to achieve an unbiased understanding of today's world -- how one `rewires' their brain which can be an arduous process. Better yet would be ways of perpetuating the youthful growth of neurons into adult years to the extent possible (he alludes briefly to this on pages 242-3). He aptly describes immigrants' disorientation even as their children have an easier time adapting. And he describes how the loss of a spouse takes a year or so to accommodate. But he doesn't go into how today's media are affecting our openness to new ideas and other cultures. So I can recommend Wexler's book as a good introduction to the process but I'll have to keep looking for ways folks can let go of obsolete religious beliefs and replace them with an up-to-date ideology.

In Wexler's final chapter he discusses how indigenous and national cultures are being overwhelmed and extinguished by the global reach of the US's culture. But the rapid advances in today's technology are not entirely the doings of the US -- Europe, Japan, Australia and even India and China are encouraging this inevitable juggernaut (as he calls it) while Islamic cultures are resisting, often violently. To avoid violent confrontations he envisions a campus-like model (he's at Yale) where individuals can be exposed to unfamiliar cultures in least threatening ways. Wexler's book is well worth while but its overprice will discourage sales.
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37. Molecular Neurobiology for the Clinician (Review of Psychiatry, Vol 22 No 3) (Review of Psychiatry)
Paperback: 282 Pages (2003-05)
list price: US$46.95 -- used & new: US$8.29
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Asin: 1585621137
Average Customer Review: 5.0 out of 5 stars
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Editorial Review

Book Description
In this authoritative volume you'll find today's most important molecularneurobiological advances and their relevance to clinicians treatingpatients with mental illness. Molecular Neurobiology for the Clinician,Review of Psychiatry, Volume 22, will update you on the latest findings,and their impact on psychiatry. You'll learn about Discoveries with thepotential to revolutionize your clinical approach by changing the ways inwhich you diagnose and treat patients The effects on psychiatry ofadvances in the molecular basis of neuronal network function, particularly in relation to abnormalities in cognitive and emotional regulation, andthe identification of novel molecular targets for drug development How toapply these discoveries to diagnosing and treating major psychiatricdisorders, including childhood- and adolescent-onset disorders,schizophrenia, drug addiction, and severe mood and anxiety disordersMolecular Neurobiology for the Clinician is an outstanding compilation ofthe best research by top names in the field. Psychiatrists, psychologists, psychiatric residents, and graduate students in neuroscience, psychiatry,and psychology will gain knowledge, understanding, and techniques forbetter diagnosis and treatment. Contents Molecular neurobiology ofchildhood- and adolescent-onset psychiatric disorders. Molecular genetics: a role in diagnosis and treatment of psychiatric disorders? Molecularneurobiology and schizophrenia: implications for etiology and treatment.Molecular mechanisms of drug addiction. Cellular neurobiology of severemood and anxiety disorders: implications for development of noveltherapeutics. Index. ... Read more

Customer Reviews (1)

5-0 out of 5 stars A fascinating read
This volume includes several excellent chapters, introducing the reader to a number of developing concepts in the world of psychiatric neuroscience.These topics are alternately discussed on a more general, easy-to-understand level, and in great technical detail - each with their own merits.The reference lists/information are also quite helpful for those wishing to pursue a topic further (for example, a thorough table of mouse knockout studies in which an anxiety-like phenotype was found).Another highlight is the excellent discussion of how the field of psychiatric genetics is coming of age.This book will prove interesting to both basic scientists and clinical psychiatrists, and even to laypersons with a particular interest in this field. ... Read more


38. THE NEUROBIOLOGY OF LEARNING AND MEMORY
by Jerry W. Rudy
 Hardcover: 500 Pages (2008-05)
list price: US$74.95 -- used & new: US$74.95
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Asin: 0878936696
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39. The Role of Microtubules in Cell Biology, Neurobiology, and Oncology (Cancer Drug Discovery and Development)
Hardcover: 690 Pages (2008-05-02)
list price: US$169.00 -- used & new: US$169.00
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Asin: 1588292940
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Book Description

Microtubule Targets in Cancer Therapy presents the first comprehensive exploration of the dynamic potential of microtubules anti-cancer targets. Written by leading anti-cancer researchers, this groundbreaking volume collects the most current microtubule research available. Among the topics examined in this volume are compounds that interact with tubulin, mechanisms and regulation by microtubule-associated proteins and drugs, MAPs, the tubulin superfamily its isotopes, peptides and depsipeptides, and neurodegenerative diseases.

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40. The Integrative Neurobiology of Affiliation (Bradford Books)
Hardcover: 432 Pages (1999-01-08)
list price: US$48.00 -- used & new: US$25.95
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Asin: 0262531585
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Editorial Review

Book Description
This book examines the biological, especially the neural, substrates of affiliation and related social behaviors. Affiliation refers to social behaviors that bring individuals closer together. This includes such associations as attachment, parent-offspring interactions, pair-bonding, and the building of coalitions. Affiliations provide a social matrix within which other behaviors, including reproduction and aggression, may occur. While reproduction and aggression also reduce the distance between individuals, their expression is regulated in part by the positive social fabric of affiliative behavior.



Until recently, researchers have paid little attention to the regulatory physiology and neural processes that subserve affiliative behaviors. The integrative approach in this book reflects the constructive interactions between those who study behavior in the context of natural history and evolution and those who study the nervous system.

The book contains the partial proceedings of a conference of the same title held in Washington, DC, in 1996. The full proceedings was published as part of the Annals of the York Academy of Sciences. ... Read more


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