Book Description
Handbook of the Toxicology of Metals is the standard reference work for physicians, toxicologists and engineers in the field of environmental and occupational health.This new edition is a comprehensive review of the effects on biological systems from metallic elements and their compounds. An entirely new structure and illustrations represent the vast array of advancements made since the last edition. Special emphasis has been placed on the toxic effects in humans with chapters on the diagnosis, treatment and prevention of metal poisoning. This up-to-date reference provides easy access to a broad range of basic toxicological data and also gives a general introduction to the toxicology of metallic compounds.

* Covers up-to-date toxicological information on 31 metallic elements and their compounds, each in a separate chapter
* New chapters on general chemistry, biological monitoring and biomarkers, essential metals, principles for prevention of the toxic effects of metals, and more ... Read more

Customer Reviews (1)

A must have reference handbook for Toxicologists and Regulatory Scientists
This book is recommended for both regulatory scientists and toxicologists dealing with metals exposures.The first 16 chapters cover fundamental concepts in metals toxicology and provide good coverage of factors important in health risk assessment.These preliminary chapters detail for the reader the myriad of issues that need to be taken into account when assessing metals and environmental data while drawing on relevant literature to illustrate points being made.Detailed reviews of individual metals are provided in subsequent chapters and it is invaluable having such in-depth coverage in a single volume.It would appear that some chapters were initially written a couple of years prior to publication so that the most recent information is not always included, but this is to be expected in such a publication.This handbook is highly recommended for anyone dealing with the toxicology of metals and is a must have for toxicologists involved in the assessment of environmental data.

Visit the Elsevier Internet site for a more detailed description of the handbooks content. ... Read more

Book Description
Dr. Osweiler presents a concise review of clinically relevant toxicants in veterinary medicine. He covers basic toxicology, including the action of poisons, therapy and antidotes; clinical toxicology of body systems; and classes of toxicants. ... Read more

Customer Reviews (1)

Easy veterinary toxicology
An effective system for veterinary learning and review in a practical format that enables you to master large amounts of information.

The book is divided into 3 sections: 1) General principles of toxicology. 2) Toxicants at the clinical level. 3) Specific agents. Perfect resources for problem-based learning. ... Read more

Book Description
The activities of modern society have unleashed a range of toxic chemicals into the global environment. Many of these toxicants are now being detected in increasing quantities in the tissues of marine mammals, most notably in top predators who acquire relatively large amounts of toxic chemicals by ingesting contaminated prey.Toxicology of Marine Mammals focuses on the effects of natural and introduced toxicants on organs and systems in marine mammals. It provides overviews on health status and contamination, with subsequent chapters devoted to whales, pinnipeds, dolphins, polar bears, manatees, and sea otters. Internationally renowned researchers assess the mounting evidence for adverse effects on reproduction and the chemically-induced increased susceptibility to death from infectious diseases. The concluding chapter addresses perspectives and issues for the future.This compelling book features research from a vast geographic landscape ranging from the tropics to the Arctic, with case studies on intriguing areas of contamination such as the St. Lawrence River and the Baltic Sea. It identifies the severe threats that environmental contaminants pose to the health and future of marine mammals. It also makes an urgent call for legislation to regulate the incessant pollution ravaging our seas and devastating the marine mammal population worldwide. Toxicologists working in marine biology and veterinary medicine, conservation scientists, fisheries scientists, environmental scientists, and wildlife managers will all benefit from this comprehensive resource. Features ... Read more

Book Description
Toxicology of Reptiles cohesively summarizes much of the cutting-edge research taking place in fields such as reptilian endocrinology, neurophysiology, immunology, and ecology. It also addresses conservation needs along with the complications often associated with population studies. The text is easy to synthesize and apply in the evaluation and understanding of potential risks to reptiles from environmental contaminants.

This book provides a comprehensive description of the current state of knowledge of reptilian toxicology from the perspective of target organ systems. It covers major contaminant classes within each chapter, focusing on those of greatest concern. The authors highlight the most pressing information gaps, and propose priority directions for further advancement in the fields of reptilian biology, wildlife and environmental toxicology, conservation, and ecological risk assessment. ... Read more

Customer Reviews (1)

Excellent reference for herpetologists, toxicologists and environmental scientists
This book is a comprehensive look at current knowledge and methods used in a booming field.This is only the second book of its kind, and does a wonderful job of presenting ideas clearly to those just starting out in the field or to professionals.It is not a casual read, but if you are looking for a scientific reference, this book is for you. ... Read more

Book Description
Why waste time guessing at what you need to know for the Toxicology certification exam? Maximize your exam preparation time with this quick-hit question and answer review. The unique question and single-answer format eliminates the guesswork associated with traditional multiple-choice Q&A reviews and reinforces only the correct answers you'll need to know on exam day. Emphasis is placed on distilling key facts and clinical pearls essential for exam success. This high-yield review for the Toxicology Boards is perfect for intense, streamlined review in the days and weeks before your exam. ... Read more

Customer Reviews (2)

Great Overview of Toxicology for board review
I purchased this book to review toxicology for my re-certification boards in Emergency Medicine.It is concise and covers most everything.Highly recommend!

The best thing to read the night before your test.
Are you getting crazy with all thoose toxic substances? This book gives you the tips that make clear the main differences between the different groups of poisons. ... Read more

Book Description
Veterinary Consult
The Veterinary Consult version of this title provides electronic access to the complete content of this book.Veterinary Consult allows you to electronically search your entire book, make notes, add highlights, and study more efficiently.Purchasing additional Veterinary Consult titles makes your learning experience even more powerful.All of the Veterinary Consult books will work together on your electronic "bookshelf", so that you can search across your entire library of veterinary books.Veterinary Consult:It's the best way to learn!

Book Description
This book covers all aspects of toxicology, including toxic diseases of large animals, small animals, and exotic pets. It provides key information on how poisons affect the body, how the body responds to a foreign substance, how poisonings are diagnosed, and how poisonings are treated. Coverage includes every organ system of every species of animal with details on each body system's susceptibility to poison. Poisons affect animals differently depending on species, breed, age, gender, health status, and reproductive status. This resource addresses these differences, allowing the veterinarian to determine the class of toxicant, the mechanism of action, and the proper course of treatment. If confronted with an unknown poison, the information in this book will assist the veterinarian in formulating a list of potential poisons based on the clinical signs that the animal is exhibiting, and in choosing the appropriate tests to narrow the list to one or a few possible poisons. ... Read more

Book Description
Principles of Toxicology Testing juxtaposes the principles of animal toxicology testing with in vitro alternative methods to highlight the importance of both fields for interpretation of the significance and relevance of the other. Beginning with the fundamentals of toxicology, the book details in vivo testing in animals and describes acute, subchronic, and chronic studies as well as toxicology testing for mutagenicity and carcinogenicity. Presenting the advantages and disadvantages of each method, it introduces in vitro alternative testing such as cellular methods for acute systemic toxicity, target organ, and local toxicity. The author considers contemporary issues such as chemical exposure, high throughput screening, and the standardization and validation of in vitro techniques. ... Read more

Book Description
A panel of researchers and experts from leading universities and major pharmaceutical companies from all over the world systematically describe cutting-edge experimental protocols for the early in vitro evaluation of new chemical entities (NCE). These readily reproducible assays measure such critical parameters as physicochemical properties, adsorption, plasma binding, metabolism, drug interactions, and toxicity. By uncovering early in the discovery stage the defects that can eliminate candidate drugs from preclinical and clinical development, these techniques can save millions of dollars in time and effort. ... Read more

Book Description
This unique text's format makes it easy to diagnose and treat occupational toxicology patients, whether they know the substance of their exposure or not. Organized by occupation, industry, and environment, it covers what agents are plausible for exposure, systemic effects, and suggested treatments. ... Read more

Customer Reviews (1)

Unique book describing occupation-specific toxic hazardsThis
The only book of its kind that examines the toxicology of work related illness by occupation. So, a practitioner faced with a patient can look up and read about the toxic hazards that are specific to that patient's job or occupation. This book rated as one of the best by the American Journal of Industrial Medicine ... Read more

Book Description
Reflecting more than a decades worth of changes, Animal Models in Toxicology, Second Edition is a practical guide to the common statistical problems encountered in toxicology and the methodologies that are available to solve them. The book presents a historical review of the use of animal models and an overview of broad considerations of metabolism and relevance used in toxicology. Individual chapters covering the eight major species used in toxicology and experimental biology form the core of the book. With contributions from experts in toxicology, toxicological pathology, and species-specific metabolism, each of these chapters provide an excellent introductory course along with guidance to the literature for more detailed understanding.

The book goes on to make the case for a range of species not commonly used for safety assessment studies but which may provide useful alternative models for some specific endpoints. The chapter authors discuss special considerations regarding theevaluation and interpretation of the clinical pathology of the eight major model species as well as how to select a model species and how to extrapolate the results to humans. They detail potential pitfalls and situations that cause either human or model to be significantly more sensitive than the other or totally irrelevant to each other. The book concludes with an overview of the increasingly complex laws and regulations that govern how laboratory animals are obtained, maintained, and utilized, and an appendix that provides a quick guide to commercial sources of laboratory animals. ... Read more

Book Description

Food and Nutritional Toxicology is the field devoted to studying the complexity of the chemicals in food, particularly those that have the potential of producing adverse health effects. This book provides a broad overview of this complex field, including areas such as: the impact on human health of food containing environmental contaminants or natural toxicants; food additives; the migration of chemicals from packaging materials into foods, and the persistence of feed and food contaminants in food products. It also addresses the impact of contaminants on nutrient utilization, adverse effects of nutrient excesses, metabolism of food toxicants, and the relationship of the body's biologic defense mechanisms to such toxicants.

Book Description
The analytical toxicologist may be required to detect, identify, and in many cases measure a wide variety of compounds in samples from almost any part of the body or in related materials such as residues in syringes or in soil. This book gives principles and practical information on the analysis of drugs and poisons in biological specimens, particularly clinical and forensic specimens.

After providing some background information the book covers aspects of sample collection, transport, storage and disposal, and sample preparation. Analytical techniques - colour tests and spectrophotometry, chromatography and electro­phoresis, mass spectrometry, and immunoassay – are covered in depth, and a chapter is devoted to the analysis of trace elements and toxic metals. General aspects of method implementation/validation and laboratory operation are detailed, as is the role of the toxicology laboratory in validating and monitoring the performance of point of care testing (POCT) devices. The book concludes with reviews of xenobiotic absorption, distribution and metabolism, pharmacokinetics, and general aspects of the interpretation of analytical toxicology results.

• A clearly written, practical, integrated approach to the basics of analytical toxicology.
• Focuses on analytical, statistical and pharmacokinetic principles rather than detailed applications.
• Assumes only a basic knowledge of analytical chemistry.
• An accompanying website provides additional material and links to related sites.

Written by an experienced team of authors, Fundamentals of Analytical Toxicology is an invaluable resource for those starting out in a career in analytical toxicology across a wide range of disciplines including clinical and forensic science, food safety, and pharmaceutical development.  ... Read more

Book Description
From health and economic consequences to exposure assessment and detoxification, this reference comprehensively covers the formation, characteristics, and control of various toxins that occur in the production, storage, handling, and preparation of food. The author discusses toxin sources, mechanisms, routes of exposure and absorption, and their chemical and biochemical components to prevent contamination of food products and reduce epidemics of foodborne disease. The book contains more than 3000 references to facilitate further research, as well as recent guidelines from the FDA and World Health Organization regarding food hygiene and safety. ... Read more

Book Description
The first book in two decades to address this multi-faceted field, The Toxicology and Biochemistry of Insecticides provides the most up-to-date information on insecticide classification, formulation, mode of action, resistance, metabolism, environmental fate, and regulatory legislation. The book draws on the authors groundbreaking research in insect detoxification. It discusses mechanisms at the molecular level such as specific enzymes that contribute to insecticide resistance, the modification of which can change insecticide susceptibility and influence host plant selections in phytophagous insects.
Beginning with a general introduction, eleven chapters integrate classical toxicology with physiology, biochemistry, and molecular biology to present a comprehensive look at the field. The book discusses the demand and formulation of pesticides and describes each type from dusts and powders to baits and aerosols. It classifies insecticides by target, chemical compound, and mechanism; evaluates toxicity testing procedures; explains pesticide uptake, mode of action, and metabolism; and explores species differences, resistance, and interactions. It also considers pesticides in the environment and federal and state regulatory legislation and enforcement.
A long-awaited, state-of-the-science review on insect toxicology, this indispensable book brings you up-to-date on the many aspects and implications of pesticide use and provides the necessary background and platform from which to conduct future research. ... Read more

Book Description
LOCATE FREQUENTLY USED INFORMATION EASILY AND QUICKLYWorking in the laboratory or office, you use a diverse assortment of basic information to design, conduct, and interpret toxicology studies and to perform risk assessments. The Second Edition of the best-selling Handbook of Toxicology gives you the information you need in a single reference source.NEW IN THIS EDITION:· Expanded coverage of inhalation toxicology, neurotoxicology, and histopathology · Additional regulatory chapters dealing with pesticides, medical devices, consumer products, and world-wide notification of new chemicals · Areas of toxicology missing from the first edition such as ecotoxicology and in vitro toxicology · A chapter providing extensive overview of the toxicology of metals · Two chapters on basic male and female endocrinology and related toxicology · Information on differences in physiological and biochemical parameters between children and adults · References to Web site sources of valuable information · Over 200 new tables and figuresTHE SINGLE SOURCE FOR THE INFORMATION YOU USE MOST FREQUENTLYUpdated and expanded, this unique book includes practical reference information useful to toxicologists in the chemical and pharmaceutical industries, contract laboratories, regulatory agencies, and academia. To help you find information quickly and easily, data is arranged by toxicology subspecialty and each chapter begins with a detailed listing of information presented. Containing over 700 tables and figures, Handbook of Toxicology, Second Edition gives you a single source for the information you use most often. ... Read more

Book Description
A source of medical, legal and regulatory information on the toxicology of human exposure to metals and chemicals, this two-volume set is designed to be the first resource professionals turn to when formulating an opinion and develping a programme. It is annually updated to provide the latest information on over 150 chemical agents in a standard format, called the TDR profile. Each profile contains the common source of exposure, toxicology, clinical manifestations, appropriate biological and medical monitoring tests, and applicable federal and state regulations. ... Read more

Book Description
Nutrients are gaining recognition for their role in protecting against the toxic effects of free radicals, alcohol and other substances. At the same time, advances in food technology, the appearance of novel foods and new ingredients have generated new toxicological issues and forced health and safety professionals to develop new and more reliable methods to assess their impact on our health. These issues are at the heart of the second edition of Nutritional Toxicology. The book discusses the role of nutrients in protecting the body against toxicants. It explores the overall importance of the metabolism of xenobiotics and antioxidant nutrients in their increasingly important role in protecting against oxidative damage generated by free radicals. The book also discusses components of the diet that can influence metabolism of drugs, how alcohol consumption affects nutritional status, and conversely, how nutritional status affects alcohol metabolism. The effect of age on the body's ability to metabolize drugs and toxicants is discussed in detail. ... Read more

Book Description
...the consistent chapter format contains an introduction,pharmacokinetics, pathophysiology, clinical presentation, lab findings,treatment, and references...completely revised and expandedwith 33 newchapters. ... Read more