41. Multiple Alignments And Database Searching Algorithmically, profile searching simply uses the dynamic programming alignmentalgorithm to the dynamic programming algorithm and maximizing the probabilty http://lectures.molgen.mpg.de/DBSearchI/MSAandDBsearch/

Online Lectures on Bioinformatics Database searching Multiple alignments and database searching Information about which residues are conserved and thus important for a particular family are crucial not only for the purpose of multiply aligning a set of sequences. Also in the context of identifying related sequences in a database this information is very valuable. Thus, a multitude of methods has been developed that aim at identifying sequences in a database which are related to a given family. Historically, the first such method had introduced the profiles described above in the context of multiple sequence alignment. Like in this application, profiles help in emphasizing conserved regions in a database search. Thus, a sequence that matches the query profile in a conserved region will receive a higher score than a database sequence matching only in a divergent part of an alignment. This feature is of enormous help in distinguishing truly related sequences. Algorithmically, profile searching simply uses the dynamic programming alignment algorithm for aligning a sequence to a profile on each sequence in the database. Of course, this is computationally quite demanding and much slower than the heuristic database search algorithms like BLAST or FASTA. Typically, the multiple alignment underlying the profile will describe a conserved domain which one expects to find within a database sequence. Therefore, in this context it is important that end gaps should not be penalized. Gap penalties for profile matching frequently vary along the profile in order to reflect the existence of gaps within the underlying multiple alignment. Through this mechanism one attempts to preferentially include new gaps in regions where gaps have been observed already. However, different suggestions exist as to the choice and derivation method for these gap penalties (Bucher, Taylor).

42. Maximizing Your Web Searches The latest news The BILLION page web Recommended Strategy for searching the InternetHow to Choose the Search Tools or Databases You Need W3 Search Engines. http://saintmary.mvn.net/searchsites1.htm

How to use a site, engine . . . w h a t e v e r New " The Gateway " for Educators Metor Search The latest news - The BILLION page web: Recommended Strategy for Searching the Internet How to Choose the Search Tools or Databases You Need W3 Search Engines Directories: Web Directories Research-It! "What-cha-ma-call-its :" Search Engine Watch Tips About Internet Search Engines Virtual Search Engines Catalogs: About.com LookSmart Local/Regional Educational Sites: St. Clair ROE - Search Engines West Central Four -Student Links Meta-Search Sites Meta search engines All-In-One Search Engines Further Study: Search Engine Tips How to Search the Web Guides To Specialized Search Engines Search Engine Showdown Visual Search Engines: Amazing Picture Machine Please let us know if you found this page useful Home MarXon Information Technology Services Try one of these:

43. BackWeb: Maximizing The Portal ROI that proactively delivers critical content across the enterprise so that usersdon't have to spend valuable time or network resources searching for mission http://www.backweb.com/corporate/

Management Team Board of Directors Employment Opportunities BackWeb Offices ... BackWeb Technology Vision The Internet has changed the nature of business operations and competition. And the widespread adoption of Web standards has revolutionalized access to electronic business applications. Now virtually any knowledge worker has the client software (a Web browser, for example) and the expertise to interact with these online applications. Enterprises looking to bolster profits by reducing costs and improving productivity are increasingly migrating to an "online" architecture to access critical content and business applications. But, what happens when knowledge workers are disconnected from the Web or LAN? The online portal and Web application architecture with all of its strengths is sub-optimal with the working requirements of the intermittently connected employee base such as customer-facing field sales and service organizations. For a sales person at a customer site or on an airplane or a technician in the field, the inability to access business systems is a significant limitation. In these kinds of situations, Web applications are unavailable at precisely those times where they can be used most productively. The productivity of these employees depends on their ability to interact with the portal or Web applications anytime anywhere, including when they are out of the office doing work and without a network connection. This new offline capability is ideal for companies that wish to capitalize on Web standards and extend the IT investments they've already made. Maximizing usage of these systems has become a critical factor in ensuring that companies are deriving maximum business value from their portals and web-based applications. Similar to e-mail systems, portals and Web apps need to go beyond online only access to allow a company's high-value, revenue generating users, such as sales and services field personnel, to do work and interact with the systems when they are on the road and disconnected from the network.

44. RMHI HerbalistRevw: How Schemes For Maximizing Health-care Industry Profits Enda of holistictype clinical assessment may be undesirable for maximizing product sales alsosuffered from its tendency to attract westerners searching for some http://www.rmhiherbal.org/review/2003-2.html

www.rmhiherbal.org - updated 2003-03-26 Herbalist Review RMHI Home Articles Catalog ... Contact us Herbalist Review, Issue 2003 #2: How schemes for maximizing health-care industry profits endanger the TCM herbal profession Tactics used by modern megacorporations to inhibit the delivery of effective health care: deceptive marketing, product design to maximize side effects, influence over educational bureaucracies, legislators, regulatory agencies, and international trade organizations. Effects on the TCM (Traditional Chinese Medicine) herbal profession are examined as a special case. Author: Roger W. Wicke, Ph.D. Page contents..... Abstract Introduction: Shareholder value vs. the public good - the modern megacorporation Marketing and product-design abuses Encourage maximum consumption with over-general product claims. Emphasize invisible benefits. Beat the drum of single-parameter double-blind testing to distract patients and practitioners from more sophisticated research paradigms. Utilize religion to enhance the placebo effect and further suppress self-awareness. Acquire testimonials from true believers. Maximize side-effects and create new markets. ... Lobbying public officials and non-profit institutions Encourage expensive regulatory schemes to put smaller competitors out of business.

45. TD Madison...Who We Are Currently Searching For specifically for venture capitalists. We understand the need to minimizeexposure while maximizing returns. Retained Executive Search http://www.tdmadison.com/venture.html

Minimize Risk-Maximize Returns Return on investment is your business. You are exacting in your standards of which businesses to fund. You spend a significant amount of money on due diligence verifying all of the aspects of the business plan. Why leave the management team to chance? After all, the management team is the riskiest part of the proposition and it is the single most important component of success. At TD Madison and Associates, we can help with a series of products designed specifically for venture capitalists. We understand the need to minimize exposure while maximizing returns. Retained Executive Search With over 60 years of experience ranging from start-up to executing turnarounds, the principals at TD Madison and Associates are well-versed in the leadership traits needed to make your venture a success. Get more information on building portfolios that perform. Leadership Audit TD Madison and Associates offers a wide range of services designed to simplify and streamline the due diligence process.

46. Seminar: Maximizing The Usefulness Of Your Library System maximizing the Usefulness of Your OPAC. knowledge of how your system indexing capabilitieswork, are needed in order to build good indexes for searching the OPAC http://www.nelinet.net/calendar/seminars/mu_03.htm

Seminars More Info... Institute and Seminar Calendar Maximizing the Usefulness of Your OPAC Librarians can enhance the user's experience and success using the OPAC by making good decisions about indexing MARC bibliographic records and customizing record displays. An understanding of both user needs and the MARC format, along with a knowledge of how your system indexing capabilities work, are needed in order to build good indexes for searching the OPAC. Knowing user preferences and display customization features of the system are essential for designing comprehensible and pleasing record displays. Come and hear from a group of librarians about "how we did it good," and "how we did it bad, but we know more now and will do it better next time." The program will include demos which highlight indexing and display issues. The day will close with a sharing session. Participants are encouraged to bring examples of indexing and/or display issues for discussion. You will learn about: Real-life experiences and lessons learned Management of the indexing and display decision process Specific indexing and display issues and how they might be addressed User satisifaction levels relating to indexing and display choices Who should attend?

47. Maximizing Performance maximizing Performance. Turning this off won't affect overall performance, butcould help if somebody is searching while somebody else is browsing. http://www.turnstyle.com/andromeda/performance.asp

Download Free evaluation Purchase Go for it! home downloads skins support Maximizing Performance There are a few things you can do the squeeze the most performance out of Andromeda. You should try these suggestions one at a time to see what the speed improvement is, as well as what features you are loosing. Make sure that you know how to make a prefs file organize your collection Sounds simple, but if you organize your collection into subfolders, that will improve load time as Andromeda will have fewer rows to draw on a single page. turn off displayNew The displayNew preference tells Andromeda to scan folders looking for new files. If it finds any, it automatically marks all folders containing them as 'new'. If you have an especially large collection this can be noticably slow. displayNew is off by default in versions 1.7.1 and up, and is on by default in all earlier versions. useImageFiles By default, Andromeda uses images stored as binary data within the script itself. You can gain an improvement by using normal image files. download the image icon files put them in the same folder with the script (the gifs are 'next to' the script) set useImageFiles to true if you want to put the images elsewhere, set imageFolderPath accordingly (ie /images/).

48. Expert Searching - Restricting Searches For example, the following search will not return any page that contains the words art , car , or auto , maximizing the chances that the pages returned will http://livinginternet.com/w/wu_expert_restrict.htm

We use 123 Domain Names UK net2 UK Domain Name Registration for .co.uk registrations Restricting Searches Summary : You can greatly narrow your search results with the "not" operator. If you get too many responses, try adding "not" clauses using keywords found on sites that you don't want to be returned. You can add always add more "not" keywords if you need to screen out more sites. For example, the following search will not return any page that contains the words "art", "car", or "auto", maximizing the chances that the pages returned will be about mustang horses. horse and mustang and not (art or car or auto) If you are getting a lot of superfluous sites from the same domain name, then you can eliminate them all at once with the URL option by adding the domain name to the "not" clause. For example, the following search with Alta Vista will not return any site with the word "motorcycle" in its URL horse and mustang and not (art or car or auto or url:motorcycle) < Previous ^ Up ... About Please visit our sponsors: Cheap Web Hosting Business Web Hosting UK Car Insurance or Life Insurance from Budget UK Mortgages Online UK Life Insurance

49. Chemical Information: Maximizing The Opportunities And Minimizing The Challenges with integration of systems; the transition from searching by intermediaries othersstlg?120 + VAT (?stlg141)Chemical Information maximizing the opportunities http://bubl.ac.uk/news/events/ev012401.htm

BUBL News: Events Chemical Information: Maximizing the Opportunities and Minimizing the Challenges University of Leeds 18 Apr 2002 Date: Wed, 23 Jan 2002 09:46:01 -0000 From: Debra L Mallett

50. MSN Careers And it is a problem for the organization as a whole if everyone is searching forface time and grandstanding with the important people rather than focusing on http://editorial.careers.msn.com/articles/creating/

document.write(''); APRIL 11, 2003 Home Working Life Workplace Issues Home Get Hired Move Ahead My Monster Post Your Resume Search Jobs Working Life Workplace Issues Work-Life Balance Equal Opportunity Shopping RESOURCE CENTER Entry Level Management Contract/Temp FOR EMPLOYERS Post a job Contact us Post a Resume Search Jobs ... Work-Life Balance Creating Visibility Grande Lum Your ability to be seen within an organization is critical. The reality is that you may be bypassed for important assignments and not receive the evaluations, salary raises and promotions you may deserve if you are not on the decision makers' radar screen. This is especially true in organizations that are large, consensus-based, matrixed and/or contain multiple decision makers which describes most organizations. On the other hand, you don't want to be seen as spending all your time self-promoting instead of doing the actual work. And it is a problem for the organization as a whole if everyone is searching for face time and grandstanding with the important people rather than focusing on the organization's goals. Here are a few ways to get noticed without hurting your credibility: Make Your Manager your Advocate Your manager's success is tied in to your success. Help your manager look good, and that manager will find ways to help you. Consider speaking directly with your manager about how to publicize your successes.

51. Canadian Retailer Searching For The Top Technologies searching for the Top Technologies By Denise Deveau. maximizing margins is what it'sall about, notes Rena Granofsky, Senior Partner with JC Williams Group in http://www.retailcouncil.org/cdnretailer/cr2002i6_toptech.asp

52. The Scouting Report: Searching The Internet Tips for Using Search Engines The key to maximizing your search with any particularsearch Despite claims, they differ in content and searching capability. http://library.law.mercer.edu/cle998/search.htm

THE SCOUTING REPORT: SEARCHING THE INTERNET USING SUBJECT INDEXES AND SEARCH ENGINES presented by Suzanne Cassidy cassidy_sl@mercer.edu Subject Indexes Subject indexes, or directories, organize Internet sites into categories of subject-specific information. Links to web pages are listed under each category. Vast amounts of information are available in hierarchical form for browsing. Some subject indexes include a search engine type option that enables you to search the contents of the indexing. Subject indexes may cover very broad, general information, such as Yahoo ( http://www.yahoo.com ), which is the largest directory with over 750,000 web sites (as of December, 1997). Alternatively, indexes may be subject specific in coverage, such as Findlaw ( http://www.findlaw.com ). As a rule, subject indexes are created by people, not computers, and frequently are enlarged by the submissions of the creators of web sites. Law-related subject indexes include: Findlaw http://www.findlaw.com Hieros Gamos http://www.hg.org

53. Accelrys: Molecular Overlay and Daylight databases through a single interface; maximizing desktop access to sampling,or systematic acyclic torsional conformational searching for your http://www.accelrys.com/dstudio/ds_medchem/ds_medex_molecular.html

@import url(/styles/products2002.css); /*IE and NN6x styles*/ CORPORATE OVERVIEW NEWSROOM EVENTS EMPLOYMENT ... CONSORTIA MEMBERS Products Modeling/Simulation Informatics Client Services Consortia ... Discovery Studio DS Molecular Overlay DS Molecular Overlay is a powerful tool for comparing geometric similarities between different molecules and their conformers. DS Molecular Overlay aligns a series of molecules either by RMS superposition of individual atoms or by field fitting, which calculates the maximum overlap of the electrostatic or steric force fields about the molecules. PDF datasheet: US Letter Product Family DS MedChem Explorer Business Unit Life Science DS MedChem Explorer Modules DS Align/Pharmacophore DS Database Access DS HypoFit DS Activity Prediction DS Property Calculator DS Conformer Generation DS Molecular Overlay DS MedChem Explorer Overview DS ADME Overview 124 Kb Two molecules overlaid using field fitting techniques. Results are displayed in a 2D chemistry spreadsheet and in high quality 3D format. In RMS superposition, molecules are aligned by calculating the best superposition of atoms such that the RMS deviation between the set of atomic coordinates is minimized. This method requires the corresponding atoms of each aligned molecule to be specified. In field fitting, molecules are aligned by calculating a force field around each molecule and determining the best superposition that maximizes the overlap of the force fields.

54. About Searching Author Tweney, Dylan Title searching is my business a gumshoe's guideto the Web. Techniques for maximizing Web productivity are presented. http://www.infomotions.com/pointers/aboutsearching.html

Previous Top Next Search ... Comments This is a description of the various information formats available through the Internet including: HTML pages, mailing lists, newsgroup postings, bibliographic citations, definitions, etc. You've heard it a million times. "You can find anything on the Internet." Well, you also know this is overstatement. Furthermore, you know that finding things on the Internet is a lot like finding a needle in a haystack, or to turn the phrase, "drinking from a firehose." On the other hand, if you know how to make Internet search engines work for you, then you might very well to be able to find what you are looking for on the Internet. The trick is knowing how to use the tools properly. In general, you should apply traditional online search techniques to your information needs. This means you must: articulate your information need as specifically as possible choose a search tool whose features accommodate the articulated need understand how to translate your need into terms the tool understands apply your search query evaluate the results repeat as necessary or until resources are expired D EFINITIONS The definitions below describe the most common features implemented by the search engines in the next section. The cited items following the definitions describe in more detail the Internet searching process. Of particular interest are the items by Duda, the Internet Scout Project, Campbell, and Zorn.

55. Maximizing Your Customer Base current thinking challenges the conventional wisdom that maximizing customer satisfactiontruly could then be created to minimize the searching activities of http://www.roperasw.com/products/loyalty/custbase.shtml

56. Tips For Maximizing Performance Tips for maximizing performance. Sentry searches for words in the order in whichdictionaries are opened, and stops searching once a word is found. http://www.wintertree-software.com/support/ssce/poorperformance.html

Sentry Spelling Checker Engine - Support Home Site index Contact us Catalog ... Search You are here: Home Support Sentry Spelling Checker Engine Tips for maximizing performance Product: Sentry Spelling Checker Engine (Windows and Source SDKs) Version: Any The Sentry spelling engine is designed and built for high performance. This document contains some tips for making Sentry run as quickly as possible. Open dictionaries (lexicons) as local files. Accessing lexicon files across a network can decrease performance, since network file access is many times slower than local file access, especially over congested networks. Open dictionaries containing frequently used words first. Sentry searches for words in the order in which dictionaries are opened, and stops searching once a word is found. Opening a dictionary containing words that appear frequently (such as the of , and a ) first reduces the time required to locate these words and improves overall performance. This is what the "ssceam.tlx" (or "sscebr.tlx", etc.) files are for: They contain the words that occur most often. Open dictionaries for one language at a time. The more dictionary files Sentry must search through, the longer the search will take, particularly when locating suggestions. Don't open the American and British English dictionaries together, for example.

57. Searching The Web General Tips for searching. These tips are designed to be general in nature. Mostsearch engines have specific tricks for maximizing the accuracy of the search. http://www.alchemymile.com/tour/search.html

Home Integration Questions Connecting ... Ed. Sites This page is designed to help you get started searching the Internet. One of the first things to cover is some terminology. What we are dealing with for our purposes here are commonly referred to as search engines. A search engine is really a front end to a very large database that contains a listing of web sites. The listing is searchable by keywords or phrases. It is this ability to search the content that makes the Internet so appealing. The following is not meant to be the definitive list, but rather a starting point. There are quite a few more search engines available, but these will give you a place to start, and if nothing else, search for other search engines. All-in-One Search Page Alta Vista: Main Page Archie Request Form Government Sources ... Yahoo Search General Tips for Searching These tips are designed to be general in nature. Most search engines have specific tricks for maximizing the accuracy of the search. Use a specific search engine's help page for the most effective search when using their site. What we will focus on, however, are some general guidelines to help you find the information you are looking for more quickly. Start with a descriptive word or a phrase that is enclosed in quotes. The quotes tell the search engine to search for the phrase EXACTLY as it appears. For example, searching for "The Black Cat" will find a match with the phrase "...did you see The Black Cat run..." but won't find "...did you see The big Black Cat run..." because the word big interrupted the search sequence.

58. Maximizing Feedback Considering that feedback is so vital to adding life to your list, are you sure you'remaximizing it to it's fullest searching for a Fast and Reliable List Host http://ezine-tips.com/list-tips/list-management/20000807.shtml

59. Smart Computing-Editorial maximizing Hard Drive Maintenance Regular Routines Will Keep It Running Smoothly. Insteadof searching all over the drive for files, a defragmentation program http://www.smartcomputing.com/editcat/SMART/STORAGE/161/14308/

Learning Series E-mail This To A Friend PC How Tos Page(s) 48-50 in print issue Maximizing Hard Drive Maintenance Regular Routines Will Keep It Running Smoothly It didn’t take long for your new hard drive to fill up with software programs, data files, video and sound files, and extra utilities you picked up off the Internet. And it took even less time for you to recognize a noticeable change in the amount of time it takes your computer to access data. Your hard drive is becoming so cluttered, at times it seems it can take twice as long to store and retrieve data than it did years (or even months) ago when you first purchased your system. Fortunately, there are a handful of things you can do to improve your hard drive’s performance and get back some of that youth and vitality you’ve been missing. In addition to discussing some of our own secrets for squeezing the best performance out of drives, we talked to several hard drive manufacturers to get their tips for improving drive performance. Clear Out The Clutter.

60. Maximizing Return On Your Database Efforts maximizing Return on Your Database Efforts June 15, 2001 by Vitus Chak. users todo things not quite possible otherwise, such as searching for individuals http://www.crossculture.com.hk/return-on-efforts.htm

Home Articles Maximizing Return on Your Database Efforts Download for a FREE tryout: The Mergemill web and database publishing tool helps you quickly and easily generate web pages and reformat data. The Deacon church management software helps you effectively manage essential information about your church congregation. The Clinicworks medical billing and dental office software helps you effectively manage essential information in your clinic operations. Maximizing Return on Your Database Efforts June 15, 2001 by Vitus Chak Despite their ubiquity, many people do not quite understand databases or recognize their value. This is partly because as front-end users, we are often so well shielded from the back-end databases and the middle-tier application logic that the whole system appears to us as a service, such as transferring fund between bank accounts using an ATM. This is of course good for the users. Another reason why we don't think seriously of databases is the lack of such needs on a personal level. We use word processors and readily see their value over paper and pen. Most of our personal database needs are essentially simple storage and retrieval, and they can often be served very well by a spreadsheet, text file, paper and pen (really), and better still a PDA with its embedded applications (though most of which are in fact dedicated databases). Setting up a database simply to keep a bunch of interesting data is possibly a waste of time. When then is a database called for? And how can we best use it?

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