41. Human Genome Project Information Information about the Project, its progress, history, and goals; issues associated with genome research; frequently asked questions, the science behind the project; and Project sponsors. http://www.ornl.gov/TechResources/Human_Genome/

The Human Genome Program of the U.S. Department of Energy funds this suite of Web sites. Gene Gateway tools for exploring the sequence The Genomes to Life program is DOE's next step in genomicsbuilding on data and resources from the Human Genome Project, the Microbial Genome Program, and systems biology to accelerate understanding of dynamic living systems. Celebrating 50 years of the discovery of the double helix DNA structure and the anticipated completion of the Human Genome Project Welcome! Explore this site for information about the U.S. and worldwide Human Genome Project. B egun in 1990, the U.S. Human Genome Project is a 13-year effort coordinated by the Department of Energy and the National Institutes of Health. The project originally was planned to last 15 years, but effective resource and technological advances have accelerated the completion date to 2003. Project goals were to identify all the approximately 30,000 genes in human DNA

42. Introduction - The Human Genome Project Introduction The Human Genome Project. National Center for Human Genome Research,National Institutes of Health. Why do the Human Genome Project? http://www.accessexcellence.org/AB/IE/Intro_The_Human_Genome.html

Introduction - The Human Genome Project National Center for Human Genome Research, National Institutes of Health. "New Tools for Tomorrow's Health Research." Bethesda, MD: Department of Health and Human Services, 1992. Since the beginning of time, people have yearned to explore the unknown, chart where they have been, and contemplate what they have found. The maps we make of these treks enable the next explorers to push ever farther the boundaries of our knowledge - about the earth, the sea, the sky, and indeed, ourselves. On a new quest to chart the innermost reaches of the human cell, scientists have now set out on biology's most important mapping expedition: the Human Genome Project. Its mission is to identify the full set of genetic instructions contained inside our cells and to read the complete text written in the language of the hereditary chemical DNA (deoxyribonucleic acid). As part of this international project, biologists, chemists, engineers, computer scientists, mathematicians, and other scientists will work together to plot out several types of biological maps that will enable researchers to find their way through the labyrinth of molecules that define the physical traits of a human being.

43. Human Gene Research Accelerating The research into classifying human genetic structure The Human Genome Project is going so well that the cooperative AngloAmerican effort should be finished a year ahead of schedule. Wired News http://www.wired.com/news/news/story/18467.html

44. Ethical Issues Of The Human Genome Project Ethical Issues of the Human Genome Project. Mapping funding. Original proposalsfor the project emphasized sequencing the entire human genome. http://www.accessexcellence.org/AB/IE/Ethical_Issues_of_the_HGP.html

Ethical Issues of the Human Genome Project "Mapping and Sequencing the Human Genome: Science, Ethics, and Public Policy." Developed by BSCS, in collaboration with the American Medical Association, under the U.S. Department of Energy Grant #DE-FG02-91ER61147. Critics express several concerns about the Human Genome Project (HGP), and most involve the extent of the project or its funding. Original proposals for the project emphasized sequencing the entire human genome. This goal, however, is controversial because of the high cost and because many critics believe that sequencing a huge amount of noncoding DNA should have low priority in a time of limited funds for research. On the other hand, most individuals involved in the project agree that detailed genetic and physical maps would be extremely useful. Therefore, mapping of the genome now is the primary goal, with complete sequencing to follow only if the cost becomes reasonable. Only about 5 percent of the genome contains sequences that are coding regions, and some biologists still maintain there is little point in sequencing the other 95 percent. Because biologists already know that several regulatory signals are in noncoding regions of DNA, a compromise has been reached. A few pilot sequencing projects are focusing on sequencing certain coding regions that are most likely to contain information valuable to the medical and biological communities. A major criticism of the HGP is similar to that raised against other mega-science projects such as the space station or the superconducting supercollider: The high cost is not justified. This big science vs. little science argument maintains that funding such large-scale projects takes scarce resources from researchers who may study certain areas of particular interest more efficiently. Conversely, others argue that coordination of the HGP is a more efficient way to conduct research in human genetics because it minimizes duplication of effort.

45. The Future Of Gene Sequencing The man who wants to take the Human Genome Project private tells a House subcommittee that his new venture shouldn't keep the federal government from continuing its funding. By Kristi Coale. Wired News http://www.wired.com/news/news/story/13079.html

46. BBC News | NEWSNIGHT | Genome Transcript - 12/2/01 JOHN SULSTON International Human Genome Project This is an iconic moment when wesay we've got to this point it's only the beginning not the end, in fact http://news.bbc.co.uk/hi/english/events/newsnight/newsid_1173000/1173801.stm

low graphics version feedback help You are in: Events: Newsnight Front Page World ... AudioVideo This transcript has been typed at speed, and therefore may contain mistakes. Newsnight accepts no responsibility for these. However, we will be happy to correct serious errors. Who owns the map of the human body? SUSAN WATTS: Wherever we look, our world has been conquered. We've trodden its contours, mapped its every detail and understand what it holds. Today, a new exploration has begun - the exploration of ourselves. Scientists have had a rough map of our genes since last summer, but only now are they beginning to make sense of this new terrain. It's turning out to be an exhilarating journey. DAVID BALTIMORE: President, California Institute of Technology Shivers ran down my spine because I realised that we were seeing human beings opened to investigation with a depth we'd never seen before. JOHN SULSTON: International Human Genome Project This is an iconic moment when we say we've got to this point - it's only the beginning not the end, in fact it's only halfway through the beginning. WATTS: SULSTON: Without that, not only would we have a privatised genome, but we would not have a genome at all.

47. Super Computer Fills In Genetic Gaps A microindustry growing as a result of the Human Genome Project is that of soupedup search engines that help researchers find matches for genes. Wired News http://www.wired.com/news/news/story/3083.html

48. BBC NEWS | In Depth | Human Genome A momentous day 26 June, 2000 Guide to how DNA makes a person The race to decodethe genome Internet links Human Genome Project Celera Genomics DNA from the http://news.bbc.co.uk/hi/english/in_depth/sci_tech/2000/human_genome/default.stm

CATEGORIES TV RADIO COMMUNICATE ... INDEX SEARCH You are in: In Depth: Human genome News Front Page World ... Programmes SERVICES Daily E-mail News Ticker Mobile/PDAs Text Only ... Help EDITIONS Change to World Monday, 6 January, 2003, 11:30 GMT Complete genome map 'in 2003' The sequencing of the human genome will be finished by next year, a leading scientist says at a conference in China. Row over 'Book of Life' Genome 'treasure trove' The essence of maleness Nature or nurture? ... 'The end of the beginning' JUNE 2000 ANNOUNCEMENT Scientists crack human code Researchers produce a rough draft of the three billion letters of genetic code that describe human life. Gene row is over What they said: Genome in quotes G-Day for biology GENOME ISSUES What the genome can do for you All the rows and all the money spent in pursuing the human code for life will be well worth it if it fulfils even some of its medical promise. Morality and a code of conduct Employment and insurance How the code was cracked Nature versus nurture ... The history of genetics ARCHIVE: GENOME MILESTONES Scientists detail rice code Researchers read the genetic code of rice - a major achievement that will have a huge impact on world food production.

49. ENU-Mouse Mutagenesis Screen In The German Human Genome Project ENUMouse Mutagenesis Screen in the German Human Genome Project http://www.gsf.de/ieg/groups/enu-mouse.html

The ENU-Mouse Mutagenesis Screen Project Index Within the German Human Genome Project ( DHGP ), we have established a research center to perform a large ENU mutagenesis screen in mouse. The research center consists of a core facility ( GSF Gene Center ) and several associated laboratories (located at the GSF Klinikum der Univ. Freiburg ). The core facility generates mutagenized F1 and G3 mice which are analyzed by the associated laboratories. Furthermore, additional screens can be performed by other research groups that are not participants of the German Human Genome Project. Scientific Concept Structure Mutants ... [GSF] last modified: 2000-06-06 Questions and suggestions to: ieg_webmaster@gsf.de

50. PROJECT GUTENBERG OFFICIAL HOME SITE -- Listing By AUTHOR Human Genome Project. http://promo.net/cgi-promo/pg/cat.cgi?&label=ID&ftpsite=ftp://ibiblio.or

51. Genome@home Project design new genes that can form working proteins in the cell. Project information and software Category Computers Computer Science Distributed Computing Projects...... What are proteins? What are genes? Why is protein design so difficult? TheHuman Genome Project; Designing new genomes; How does this project help? http://genomeathome.stanford.edu/

52. News.nabou.com - Genetics News Features stories on the Human Genome Project, human cloning, gm foods and general human genetic news and information. http://news.nabou.com/sci-tech/genetics_news.html

The most comprehensive internet news website Search News Science and Technology Sections: Science news Cancer news Environment news Genetics news Medical news Public health news Biological sciences news Human sciences news Physical sciences news Space science news UK medical news Top technology stories Tech latest Technology features ASP news Communications equipment news Computer games news Computer security news Computer services news Database industry news Developer news Enterprise computing news Graphics industry news Handhelds news Imaging equipment news Java news Knowledge management news Linux news OS news Open source news PC industry news

53. The Human Genome Project-Key Text The Human Genome Project – discovering the human blueprint, Published by TheHuman Genome Project – A feat so vast that at first it seems unachievable. http://www.science.org.au/nova/006/006key.htm

Key text Published by Australian Academy of Science Sponsored by In what has been called the Everest of modern biology, scientists from around the world are collaborating in an ambitious attempt to unravel and record the entire set of human genetic instructions. You will get more from this topic if you have mastered the basics of DNA and genes Printer-friendly version of complete topic How the project began The idea of the Human Genome Project first began in a vague way in the 1970s when biologists started to investigate human genes at the molecular level. As biochemical analysis of DNA (deoxyribonucleic acid) became possible, it became clear that certain segments of DNA (called markers) were associated with particular conditions. Various countries started to map parts of the human genome in the 1980s but the international project really got under way when the USA became involved. In 1989, the Human Genome Organisation (HUGO) was founded by leading scientists in the field to coordinate the massive international effort now involved in unravelling the secrets of our genes. The project aims to map the position of every human gene and to read and decipher every message encoded in the the twisted double helix of our DNA ( Box 1 ). It is a stupendous and very costly undertaking, involving advanced biotechnology, and will take many years to complete. A first draft of the human genome was announced in June 2000.

54. PROJECT GUTENBERG OFFICIAL HOME SITE -- Listing By AUTHOR Human Genome Project. http://promo.net/cgi-promo/pg/cat.cgi?&label=ID&ftpsite=ftp://ibiblio.or

55. Stanford - Morrison Institute - HGDP Frequently Asked Questions This a list of frequently asked questions of the Human Genome DiversityProject. Is this Project part of the Human Genome Project? No. http://www.stanford.edu/group/morrinst/hgdp/faq.html

Home About the Institute Colloquia Financial Assistance (Stanford) Human Genome Diversity Project Related Organizations Frequently Asked Questions Prepared by the Project's North American Committee The Human Genome Diversity Project (the "HGD Project") is an international project that seeks to understand the diversity and unity of the entire human species. The HGD Project is still largely in its planning stages, seeking the best ways to reach its goals. We hope this document will provide important background information to help people gain a better understanding of this evolving initiative. It was written by the North American Committee of the HGD Project in late 1993 and early 1994 to respond to questions committee members were frequently asked. It represents the views of that Committee at that time. What is the Human Genome Diversity Project? Why is the HGD Project important? Is this Project part of the Human Genome Project? How is the HGD Project organized? ... How can I get more information about the Human Genome Diversity Project? What is the Human Genome Diversity Project? The HGD Project is an effort by anthropologists, geneticists, doctors, linguists, and other scholars from around the world to document the genetic variation of the human species worldwide. This scientific endeavor is designed to collect information on human genome variation to help us understand the genetic makeup of all of humanity and not just some of its parts. The information will also be used to learn about human biological history, the biological relationships among different human groups, and may be useful in understanding the causes of and determining the treatment of particular human diseases.

56. Links To The Genetic World: 1 Human Genome Project compiled links in Bioinformatics http://www.ornl.gov/TechResources/Human_Genome/links.html#informatics

skip navigation Links to the Genetic World Subject Index Alphabetical Index News What's New Genetics Headlines Human Genome News Meetings Calendar ... Media Guide Basic Information FAQs Glossary Acronyms Links ... Publications About the Project What is it? Goals Progress History ... Genetics 101 the New Genetics Home Gene Testing Gene Therapy Pharmacogenomics ... Genetic Counseling Ethical, Legal, Social Issues Home Privacy Legislation Gene Testing Patenting ... Genetics in Courtroom Education Teachers Careers Students Webcasts Audio/Video ... Genética Websites en Español Research in Progress Home Sequencing Instrumentation Mapping ... Funding Publications Human Genome News Chromosome Poster Primer Molecular Genetics To Know Ourselves ... List of All Publications Search This Site Contact Us Privacy Statement Site Stats and Credits No endorsement is made or implied by inclusion here. QuickLinks: This Page: Human Genome Project Progress In Genome Projects Genetics and Life Sciences Protein Research ... Research Sites Page 2: Research Databases Resources Tools Software ... Bioremediation Page 3: Ethical, Legal, and Social Issues

57. Your Genes, Your Choices: Exploring The Issues Raised By Genetic Research Your Genes, Your Choices describes the Human Genome Project, the science behind it, and the ethical, legal, and social issues that are raised by the project. http://ehrweb.aaas.org/ehr/books/

Table of Contents Your Genes, Your Choices describes the Human Genome Project, the science behind it, and the ethical, legal, and social issues that are raised by the project. This book was written as part of the Science + Literacy for Health project of the American Association for the Advancement of Science (AAAS) and funded by the U.S. Department of Energy AAAS has a strong commitment to science literacy and the public understanding of science. Through its Directorate for Education and Human Resources Programs, AAAS has been a leader in identifying and meeting the needs of underrepresented groups in science. Science + Literacy for Health fits into this vision of making science accessible to everyone. Most people think that science is remote from the work they do, the lives they lead, and the decisions that they make day by day. Nothing could be further from the truth. Your Genes, Your Choices points out how the progress of science can potentially "invade" your life in the most direct ways, affecting the choices you make at the grocery store, your own health care and that of your family, and even your reproductive decisions. The connection between science and health is a direct one, and your ability to understand the science behind health affects your ability to understand the issues and the stakes. Science may seem difficult, because scientists often use technical language to talk about abstract ideas. This book has been written to introduce you to important ideas, but also to convince you that you can understand the basic concepts of science and that it is important to do so.

58. Wired News: Will Gene-Control Report Curb Power, Or Spur Clash? The Human Genome Project's socialissues group is demanding greater autonomy and more funds. A milestone report comes out next month. Wired News http://www.wired.com/news/technology/0,1282,962,00.html

Welcome to Wired News. Skip directly to: Search Box Section Navigation Content Search: Wired News Animations Wired Magazine HotBot (the Web) Will Gene-Control Report Curb Power, or Spur Clash? Page 1 of 1 08:00 PM Dec. 12, 1996 PT A milestone will be reached next month in the battle between the geneticists who control the Human Genome Project and the health, social science, and legal professionals who compose its Ethical, Legal, and Social Issues (ELSI) Working Group. An outside group headed by Drs. Mark Rothstein of Houston University and Anne Spence of the University of California will issue a report on the group's demand for more money, greater autonomy, its own budget, and the right to report to Congress or the White House rather than to the scientists. If the group supports ELSI demands and the project's advisory council acquiesces, it could significantly reduce the geneticists' and biotech industry's power to determine the pace, funding, and use of genetic research. Story Tools Today's Top 5 Stories Get the Skinny on Food Poisoning Misfired Messages Roil Businesses States Halt Smallpox Shots Gates' Hefty Aid to HIV Research ... Stem Cells Fill Hearts With Hope The fight, recalling C. P. Snow's classic description of the "two culture" clash between scientists and humanists, is precipitated by the geneticists' epic success in identifying the human genome. Ethicists say the explosion in our ability to diagnose illness for which there is no known therapy could create enormous new problems - for employment, insurance, privacy, family relations, and personal psychology - unless the scientists are reined in. The geneticists fear that such social concerns will retard scientific progress and its promise for preventing disease and helping people live longer.

59. Moved Similar pages More results from www.sciencemag.org HGMPRC Fugu Genomics Project The group, headed by Greg Elgar, is involved in a number of projects geared towardsunderstanding sequence data generated by the Human Genome Project. http://www.sciencemag.org/genome2001/1195.html

This page has moved, the new location is http://www.sciencemag.org/cgi/content/short/291/5507/1195

60. PROJECT GUTENBERG OFFICIAL HOME SITE -- Listing By AUTHOR Human Genome Project. http://promo.net/cgi-promo/pg/cat.cgi?&label=ID&ftpsite=ftp://ibiblio.or

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