81. MPIbpc 25 Years - Biomedical Nuclear Magnetic Resonance 1996) Next Page BIOMEDIZINISCHE NMR Forschungs GmbH. Biomedical NuclearMagnetic Resonance -. Director Jens Frahm. Wolfgang Hänicke http://www.mpibpc.gwdg.de/inform/25years/Frahm.html

BIOMEDIZINISCHE NMR Forschungs GmbH - Biomedical Nuclear Magnetic Resonance - Director: Jens Frahm development and application of spatially resolved NMR; noninvasive neurobiology; human neuroscience; structural, metabolic, and functional studies; brain disorders in childhood; animal studies of acute stoke; functional mapping of neuronal activation; cognitive information processing in humans The application of spatially resolved nuclear magnetic resonance (NMR) in the life sciences is unique as it provides noninvasive insights into the anatomy, metabolism, and function of intact human (and animal) organ systems. Magnetic resonance imaging (MRI) and localized spectroscopy (MRS) allow us to raise questions ranging from basic biologic research to medical diagnosis, and to investigate humans, animals, perfused organs, tissue extracts, and cell suspensions in comparable experiments. It is our primary aim to further pertinent approaches for a better understanding of the functioning human brain under physiologic and pathologic conditions. Subsequent to the development of a fast scan MRI principle - a scientific, clinical, and economic breakthrough - current MRS projects extend our questions to human brain metabolism and its pathologic alterations, as well as to the relations between structure, metabolism, and function. Figure 1 shows typical proton NMR spectra of major metabolites in gray and white matter of a healthy human subject.

82. Nuclear Magnetic Resonance nuclear magnetic resonance. The Basics of NMR, by Joseph P. Hornak, Ph.D. OpenDirectory Science Chemistry nuclear magnetic resonance - Netscape. http://www.spincore.com/nmrinfo/nmr_s.html

Nuclear Magnetic Resonance NMR - What is it? The Basics of NMR, by Joseph P. Hornak, Ph.D. Open Directory - Science: Chemistry: Nuclear Magnetic Resonance NMR Spectroscopy. Principles and Application. Six second year lectures given at Imperial College by Henry Rzepa. NMR Tutorial, courtesy of Dr. Alex Grushow, Rider University. Basic MR Principles by Wm. Faulkner, OutSource, Inc.. 2D NMR Spectroscopy On-line WWW NMR Systems The World-Wide Web NMR Spectrometer, University of Florida. Virtual NMR Experiments UIUC Virtual Spectrometer NMR Reference Desk NMR BOOKS a collection provided by NMR WWW server in Spain. NMR SPECTRA The FTNMR FID Archive - a collection of 1H and 13C FID data sets for small organic molecules. NMR CHEMICAL SHIFTS BioMagResBank - a database of chemical shifts, Univ. of Wisconsin. WWW Database System of 1H and 13C spectra and assignments H- Wizard and C Database - Enter chemical shifts [ppm] NMR PERIODIC TABLES TAMU's Enhanced NMR Periodic Table by the BMRL University of Illinois by the Potsdam University NMR SAFETY NMR SOFTWARE NMR School: NMR Concepts - a non-profit, tax-exempt NMR School

83. School Of Physics And Astronomy nuclear magnetic resonance Home Page. Staff Sciences. The activitiesin the field of nuclear magnetic resonance in the school include http://www.nottingham.ac.uk/~ppzqsp/nmr.htm

Home University Sitemap Help On this page: Nuclear Magnetic Resonance Further Information: NMR Home Page Contacting us PhD Opportunities Postgraduate Info ... Safety Nuclear Magnetic Resonance Home Page Staff: Dr AJ Horsewill, Dr Helen Geen and Dr JR Owers-Bradley News: The School of Physics and Astronomy has recently been awarded a Basic Technology grant for the Production and Exploitation of Hyperpolarised Species for Medical and Materials Sciences. The activities in the field of Nuclear Magnetic Resonance in the school include: Quantum Molecular Tunnelling Basic Technology - Production and Exploitation of Hyperpolarised Species for Medical and Materials Sciences Solid State NMR Quantum Fluids ... Spin Dynamics in Solid Xenon Details of other NMR projects related to MRI can be found on the Magnetic Resonance Imaging and Spectroscopy website.

84. Nuclear Magnetic Resonance nuclear magnetic resonance More details coming soon. The Institute ofMaterials Processing, as part of Michigan Technological University http://www.imp.mtu.edu/matchar/nuclear_mag.html

IMP HOME STAFF CHARACTERIZATION Nuclear Magnetic Resonance More details coming soon. The Institute of Materials Processing, as part of Michigan Technological University, has arrangements with several university departments to utilize their most advanced material characterization equipment and expertise. Back to Material Characterization Michigan Technological University Michigan Technological University is an equal opportunity educational institution/equal opportunity employer.

85. Biophysical Chemistry - Nuclear Magnetic Resonance Biophysical Chemistry. nuclear magnetic resonance Application anddevelopment of NMR methodology and theory. The nuclear magnetic http://www.fkem2.lth.se/research/areas/nmr.html

Staff Former Members Education Courses (in Swedish) ... Research Areas / Nuclear Magnetic Resonance Biophysical Chemistry Nuclear Magnetic Resonance Application and development of NMR methodology and theory The nuclear magnetic resonance phenomenon underlies a large and growing family of experimental techniques for investigating the structure, dynamics and interactions of condensed matter on length scales from the molecular to the macroscopic, and on time scales from picoseconds to hours and longer. Forty years ago, when NMR had become an established method in chemical research, about 2,000 papers had been published in the NMR field. Today, a similar number of NMR papers are added to the literature every five weeks in fields ranging from solid-state physics to neurophysiology. No other physical probe of molecular behavior can rival NMR in range of applications and potential for development. During the past two decades, the biomolecular and medical applications of NMR have been transformed by major methodological breakthroughs and today they dominate the field. NMR is used in one way or another in the majority of the biophysical research projects undertaken in the Department. We use NMR to determine the three-dimensional structures of proteins in solution, to characterize conformational dynamics essential for protein function, and to study the interactions of proteins and nucleic acids with other molecules, including water, co-solvents and ions, functional ligands and other biomolecules.

86. Netconferences.net http://lasher.vei.co.uk/nmrec3/

Netconferences Welcome to virtual conferencing. For details of our upcoming Eurotron glycoscience conferences, click here

87. NMR Knowledge Base - The Well-known Nuclear Magnetic Resonance Spectroscopy Site ATOMIC, IR, MRI, MS, NMR, RAMAN, UV, XRAY, CHEMOMETRICS, PROTEOMICS, The wellknown nuclear magnetic resonance Spectroscopy site. brought to you by. Username,Password, http://www.nmr.de/

ATOMIC IR MRI MS ... PROTEOMICS The well known Nuclear Magnetic Resonance Spectroscopy site brought to you by Username Password Only required for enhanced features FEATURES A primer for nuclear magnetic relaxation in liquids 03 March 2003 This article is a primer that is intended to serve as a concise source of information for researchers interested in learning relaxation aspects in NMR. [More...] NMR Knowledge Base's Online Books 19 February 2003 Permanently housed in the Education section, the NMR online books currently feature the following titles: Applications of H NMR Spectroscopy Product Operators and Coherence Selection Selected chapters of modern NMR-spectroscopy ... - Top Accessed Papers in 2002 19 February 2003 Discover the four most accessed MRC papers in 2002 through Wiley InterScience . Free access is granted to the No. 1 top accessed paper for all spectroscopyNOW users. [More...] NEWS Next-Generation Avance Architecture Delivers Increased NMR Performance and Functionality 12 March 2003 [More...] New Biological Solid-State NMR Probes from Bruker Biospin Deliver Increased Sensitivity in High Field Magnets 11 March 2003 [More...]

88. Nuclear Magnetic Resonance Spectrometer The 750MHz nuclear magnetic resonance (NMR) spectrometer in the William R. WileyEnvironmental Molecular Sciences Laboratory High Field Magnetic Resonance http://picturethis.pnl.gov/picturet.nsf/by id/SMAA-477QHM?opendocument

89. IBS : Welcome Page Of The Laboratory Of Nuclear Magnetic Resonance (Laboratoire Laboratoire de Résonance Magnétique Nucléaire. LABORATORY OF. NUCLEAR MAGNETICRESONANCE. Contact. LABORATORY OF. nuclear magnetic resonance. Contact. http://www.ibs.fr/ext/labos/LRMN/welcome_en.htm

LABORATORY OF NUCLEAR MAGNETIC RESONANCE Contact. webLrmn@ibs.fr ... Research projects and Publications Software developments The 1999 Scientific Report about this laboratory (in French; parts of the CDRom) Back to the IBS Home-Page LABORATORY OF NUCLEAR MAGNETIC RESONANCE Contact. webLrmn@ibs.fr Laboratory Head Dominique MARION Key-words Scientific topics Nuclear Magnetic Resonance - Heteronuclear Relaxation - Molecular Dynamics - Structure Determination - Cytochromes - Snake Venom Toxins Methods Anisotropic diffusion analysis - Residual Dipolar Coupling Dynamic Model Analysis - Multiconformational Analysis PROJECTS NMR Development. st project) Development of Structure Calculations. nd project) Cytochromes c. rd project) Thioredoxins th project) Snake Venom Toxins. (5 th project) Other proteins. th project) Protein p21-WAF1. (7 th project) PUBLICATIONS The most significant publications. The most significant publications (parts of the 1999 Scientific Report; in French) Back to the IBS Home-Page Last updated : August 2 2001 For any request and suggestion, please, send a mail to:

90. Extending The Power Of Nuclear Magnetic Resonance Techniques Both nuclear magnetic resonance (NMR) spectroscopy and magnetic resonance imaging(MRI) are based on the tiny magnetic moments produced by the. http://www.er.doe.gov/Sub/Accomplishments/Decades_Discovery/18.html

Printer-friendly version Extending the Power of Nuclear Magnetic Resonance Techniques A larger .pdf version of this figure is available at the URL listed below. Scientific Impact: These novel concepts and techniques have revolutionized the study of structure, dynamics, and function in solid materials and other systems that previously were inaccessible to NMR investigations. Low-field MRI is ideal for studying highly porous, magnetic materials and fossils and rocks. Social Impact: These techniques and instruments have been licensed and incorporated into commercial NMR technology used worldwide. A company has licensed the low-field MRI technology to develop medical applications. In addition, Pines has trained about 200 scientists, of whom many now hold leading positions in academia and industry. Reference: Y.Q. Song, B.M. Goodson, and A. Pines, "NMR and MRI Using Laser-Polarized Xenon," Spectroscopy , (14) 26-33 (July 1999). URL: http://www.lbl.gov/msd/PIs/Pines/99/99_1_Low_field.html Technical Contact: Don Freeburn, Office of Basic Energy Sciences, 301-903-3156

91. Nuclear Magnetic Resonance Spectroscopy - RTI International nuclear magnetic resonance Spectroscopy RTI International Webpage -Advanced capabilities for measuring chemical compounds and isotopes. http://www.rti.org/page.cfm?objectid=FFAC7910-8EAD-42FC-AEAA54B1EEB489EE

92. Wadsworth-Cores Nuclear Magnetic Resonance Structural Biology Wadsworth Center. nuclear magnetic resonance Structural Biology.The nuclear magnetic resonance (NMR) Structural Biology Facility http://www.wadsworth.org/cores/nmr.htm

Nuclear Magnetic Resonance Structural Biology The Nuclear Magnetic Resonance (NMR) Structural Biology Facility carries out studies on a diverse array of biologically relevant systems in order to obtain detailed structural information. Analysis of such systems under physiological solution conditions can generate three-dimensional structure data and molecular flexibility/rigidity information and allows the detailed investigation of exactly how biomolecules carry out their designated function. Additionally, appropriate interactions between such molecules can be conveniently studied. The NMR Structural Biology Facility can be used to assist in the work of research groups of the Wadsworth Center. These studies proceed as collaborative arrangements with staff members of the NMR group. Initial questions concerning the feasibility of projects for NMR study should be directed to the facility's Director. It is anticipated that many appropriate projects will develop into work fundable by external agencies. Complete involvement at all stages of investigation by collaborators is encouraged under the supervision on NMR group members. The NMR facilty has two NMR instruments, Bruker 500 and 600 MHz.

93. The Scientist - Prions' Changeability: Nuclear Magnetic Resonance Shows More Pie 10, 1999, '); //. News. Prions' Changeability nuclear magnetic resonanceshows more pieces of the puzzle. By Ricki Lewis. Prions have been a tough sell. http://www.the-scientist.com/yr1999/may/lewis_p1_990510.html

The Scientist 13[10]:1, May. 10, 1999 News Prions' Changeability: Nuclear magnetic resonance shows more pieces of the puzzle By Ricki Lewis Prions have been a tough sell. Against a backdrop of the "DNA to RNA to protein" credo, the idea that the same amino acid sequence could exist in multiple forms, both normal and deranged, seemed like heresy. But since Stanley Prusiner , a professor of neurology, virology, and biochemistry at the University of California, San Francisco (UCSF), named the agent that causes the transmissible spongiform encephalopathies (TSEs) "proteinaceous infectious particles" in 1982, evidence has been steadily accumulating that these prion proteins can indeed set up a deadly chain reaction that renders the brains of 85 mammalian species similar in appearance to Swiss cheese. Yet despite the mounting evidence, many demonstrations of prion action have been inferred, indirect, or incomplete. A view of how the same molecule can take on different guises has been lackinguntil now. Thomas James , chairman of the department of pharmaceutical chemistry at UCSF, with Prusiner and others, has identified the changeling part of the prion protein (PrP).

94. 8.8 Nuclear Magnetic Resonance 8.8 nuclear magnetic resonance. In the presence of a magnetic field, nuclei withnonzero nuclear spin have a discrete number of possible energy levels. http://www.irc.leeds.ac.uk/iaps/mod2/node67.html

Next: 8.8.1 Relaxation Mechanisms Up: 8 Experimental Techniques Previous: 8.7 Infrared Dichroism 8.8 Nuclear Magnetic Resonance In the presence of a magnetic field, nuclei with non-zero nuclear spin have a discrete number of possible energy levels. Application of a radiofrequency pulse of the correct frequency can stimulate the nuclei into a higher energy state - the resonance condition. Nuclei with even atomic number, Z , and even atomic weight, A , possess zero spin; if A is even and Z odd the spin is an integer value; all other conditions result in half-integer values of spin. The spin is measured in units of h /2 where h is Planck's constant. The spin is characterised by the spin quantum number I = 1/2, 1, /2, 2, 5/2, ...etc. Thus H, C and F all have I = 1/2, Li, D and N have I = 1, and Na and Cl have I = 3/2 . C and O both have zero spin. The number of energy levels is (2 I +1), thus nuclei of spin 1/2 have two possible energy levels and align either parallel or anti-parallel to the applied magnetic field; I = 1 results in three possible energy levels. The magnetic moment

95. JosseyBass :: Encyclopedia Of Nuclear Magnetic Resonance, Volume 9, Advances In JosseyBass, Encyclopedia of nuclear magnetic resonance, Volume9, Advances in NMR by David M. Grant, Robin K. Harris. http://www.josseybass.com/cda/product/0,,0471490822,00.html

By Keyword By Title By Author By ISBN By ISSN Shopping Cart My Account Help Contact Us ... NMR Spectroscopy Encyclopedia of Nuclear Magnetic Resonance, Volume 9, Advances in NMR Related Subjects General Imaging General Spectroscopy Mass Spectrometry Related Titles By These Authors Encyclopedia of Nuclear Magnetic Resonance, 9 volume set (Hardcover) Encyclopedia of Nuclear Magnetic Resonance, 8 Volume Set (Hardcover) Encyclopedia of Nuclear Magnetic Resonance, Volume 1, Historical Perspectives (Hardcover) NMR Spectroscopy Structure Elucidation by NMR in Organic Chemistry: A Practical Guide, 3rd Revised Edition (Hardcover) Eberhard Breitmaier Structure Elucidation by NMR in Organic Chemistry: A Practical Guide, 3rd Revised Edition (Paperback) Eberhard Breitmaier Proton and Carbon NMR Spectra of Polymers, 5th Edition (Hardcover) Nuclear Magnetic Resonance: Concepts and Methods (Paperback) Daniel Canet Carbon 13 NMR Spectroscopy (Hardcover) Hans-Otto Kalinowski, Stefan Berger, Siegmar Braun NMR Spectroscopy Encyclopedia of Nuclear Magnetic Resonance, Volume 9, Advances in NMR

96. JosseyBass :: Encyclopedia Of Nuclear Magnetic Resonance, 9 Volume Set JosseyBass, Encyclopedia of nuclear magnetic resonance, 9 volumeset by David M. Grant (Editor), Robin K. Harris (Editor). http://www.josseybass.com/cda/product/0,,0470847840,00.html

By Keyword By Title By Author By ISBN By ISSN Shopping Cart My Account Help Contact Us ... NMR Spectroscopy Encyclopedia of Nuclear Magnetic Resonance, 9 volume set Related Subjects General Imaging General Spectroscopy Mass Spectrometry Related Titles By These Authors Encyclopedia of Nuclear Magnetic Resonance, 8 Volume Set (Hardcover) Encyclopedia of Nuclear Magnetic Resonance, Volume 9, Advances in NMR (Hardcover) Encyclopedia of Nuclear Magnetic Resonance, Volume 1, Historical Perspectives (Hardcover) NMR Spectroscopy Structure Elucidation by NMR in Organic Chemistry: A Practical Guide, 3rd Revised Edition (Hardcover) Eberhard Breitmaier Structure Elucidation by NMR in Organic Chemistry: A Practical Guide, 3rd Revised Edition (Paperback) Eberhard Breitmaier Proton and Carbon NMR Spectra of Polymers, 5th Edition (Hardcover) Nuclear Magnetic Resonance: Concepts and Methods (Paperback) Daniel Canet Carbon 13 NMR Spectroscopy (Hardcover) Hans-Otto Kalinowski, Stefan Berger, Siegmar Braun NMR Spectroscopy Encyclopedia of Nuclear Magnetic Resonance, 9 volume set

97. RPL Capabilities - Nuclear Magnetic Resonance (NMR) Radiological nuclear magnetic resonance Laboratory. Nuclear magneticresonance (NMR) methods have been exploited by chemists to study http://rpl.pnl.gov/cap_nmr.stm

Home Organization Overview Capabilities Projects ... Related Links Radiological Nuclear Magnetic Resonance Laboratory Nuclear magnetic resonance (NMR) methods have been exploited by chemists to study innumerable chemical systems. The maturity of the techniques is such that they are routinely used in the study of organic, organometallic, and coordination compounds; including very complex molecules such as proteins, enzymes, and DNA. Indeed, magnetic resonance is used to image humans for medical diagnostics (MRI). Yet, capabilities to study radioactive materials by magnetic resonance techniques are very limited. With this in mind, PNNL researchers set out to establish a facility specifically designed for NMR examination of radioactive materials. This effort has culminated in the RPL Radiological NMR Laboratory. This facility houses two NMR spectrometers-a 300 MHz spectrometer and a variable field spectrometer. The 300 MHz NMR spectrometer is built around an Oxford Instruments 300 MHz superconducting magnet. Currently a two-channel, 5 mm MAS probe for solids and a two-channel 10 mm liquids probe are available for work with high dose radioactive materials. Both probes have one broadband channel and one proton-decoupling channel. The facility was designed for investigation of radioactive materials in the environment, radioactive tank waste, Pu bearing materials, and other DOE mission active areas as well as fundamental studies of actinide metal salts.

98. Biomolecular Structure Analysis By Nuclear Magnetic Resonance Biomolecular Structure Analysis by nuclear magnetic resonance. David E.Wemmer, Lawrence Berkeley National Laboratory. Research Objectives. http://www.nersc.gov/research/annrep98/wemmer.html

1998 Annual Report Biological and Environmental Research Biomolecular Structure Analysis by Nuclear Magnetic Resonance David E. Wemmer, Lawrence Berkeley National Laboratory Research Objectives The focus of our work is to understand structure-function relationships in biomolecules and their complexes by applying methods of modern multidimensional nuclear magnetic resonance (NMR). Computational Approach There are two major stages in the analysis of NMR data which rely heavily on computation. The first is optimized transformation of the time domain NMR data into frequency dimensions. To extend resolution, this transformation uses linear prediction or maximum entropy analysis, followed by Fourier transformation. Artifacts are removed from the data using iterative modeling of various sorts. The second stage of the analysis is in conversion of NMR-derived structural restraints, together with knowledge of the covalent structure of the molecule, into sets of coordinates (models) that are consistent with all experimental observations. This can be done through molecular-dynamics calculations in either Cartesian or internal angle spaces. These models are analyzed to determine the structure-function relationships of interest. Accomplishments Time allocated in the past year was used to explore both the data analysis and structure refinement steps. Unfortunately, the analysis program PROSA, though functional on other supercomputers, could not load experimental data when run on the Cray C90. However, the real-space refinement program AMBER was run to analyze the structure of an aptamer DNA (one found through an in vitro selection for arginine binding) in complex with its target. The results indicate a complex folded structure and demonstrate clear structural changes upon binding.

99. ISI AS CR - Nuclear Magnetic Resonance nuclear magnetic resonance, The nuclear magnetic resonance Departmentwas founded at ISI by Dr. J. Dadok in 1960. He was already http://www.isibrno.cz/info.new/celky/popis/e-01.htm

Institute of Scientific Instruments of the AS CR Czech SCIENTIFIC SECTIONS The Structure of Organisation Scientific Sections Electron Optics Nuclear Magnetic Resonance Coherence Optics Not possible to figure the menu without scripting! NUCLEAR MAGNETIC RESONANCE Head of the Section: Doc. Ing. Miroslav Kasal , CSc. Scientific Board Member Laboratory of NMR Tomography and Localised Spectroscopy Laboratory of NMR Electronics Laboratory of Magnetic Fields and Cryogenics Nuclear magnetic resonance is a spectrometric method for quantitative and qualitative analysis of unknown materials. Up Webmaster

100. Nuclear Magnetic Resonance nuclear magnetic resonance (NMR). nuclear magnetic resonance is a radiofrequencyspectroscopy which measures the size of these splittings. http://www.phy.mtu.edu/~suits/NMR.html

Nuclear Magnetic Resonance (NMR) Small splittings in the energy levels of nuclei can occur in the presence of a magnetic field. Nuclear Magnetic Resonance is a radiofrequency spectroscopy which measures the size of these splittings. Typical splittings correspond to frequencies of 10 to 100 MHz, in contrast to optical spectroscopy where the frequencies are measured in terahertz (10 Hz or 1 million MHz). The most common nucleus used for NMR is the hydrogen nucleus. This is not only because hydrogen is present in many important compounds (such as all organic compounds and water) but also hydrogen is one of the easiest nuclei to observe using NMR. Most of the energy level splitting observed is due to the Zeeman interaction between the nuclear magnetic dipole moment and an externally applied magnetic field. If this were the only effect, then NMR would not be of great use since all compounds would respond at the same frequency. However, small shifts in the splittings occur from compound to compound making NMR a sensitve method to look at the molecular structure at a microscopic level. In the best cases, shifts as small as a few Hz can be observed. The most commonly observed frequency shifts are typically measured in parts per million (ppm). Thus, for example, a 10 ppm shift for a 100 MHz splitting would correspond to 1000 Hz = 1 kHz. Back

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