41. Behçet's Disease And Recurrent Aphthous Stomatitis acrodynia (Pink disease) Oral and perioral ulceration, hypersalivation, gingivitisand early tooth loss are features of acrodynia caused by mercury poisoning http://www.geocities.com/stantonios/mc/aphthous.html

Behçet's Disease (Behçet, 1937) and Recurrent Aphthous Stomatitis http://www.medicad.com Behçet's disease (BD) is a chronic multisystem disorder characterized mainly by a triad of (1) recurrent aphthous stomatitis (RAS), (2) genital ulcers, and (3) ocular lesions. BD more commonly affects individuals of Mediterranean origin, from the Middle East, China, Korea and Japan. There is an association with HLA-B5 and HLA-B51. Clinical Manifestations: I. Major criteria: Recurrent aphthous stomatitis (RAS): in 90%-100% of cases. Recurrent painful genital ulcers that tend to heal with scars: in 64%-88% of cases. Ocular lesions: Uveitis with conjunctivitis (early) and hypopyon (late), retinal vasculitis (posterior uveitis) that may result in blindness, iridocyclitis and optic atrophy. CNS lesions: meningoencephalitis, cerebral infarction, psychosis, cranial nerve palsies, cerebellar and spinal cord lesions, hemi- and quadriparesis. Skin lesions: erythema nodosum, papulopustular lesions and acneform nodules.

42. How Can Mercury Affect Children? or arms. acrodynia (Pink Disease). Kidney damage is very common afterexposure to toxic levels of inorganic mercury. Metallic mercury http://allergies.about.com/library/chem/blchem-mercury5.htm

zfp=-1 About Allergies Search in this topic on About on the Web in Products Web Hosting Allergies with Judy Tidwell Your Guide to one of hundreds of sites This page sponsored by Home Articles Forums Chat ... Help zmhp('style="color:#fff"') Subjects ESSENTIALS Allergy Symptoms Food Allergies/Intolerances Skin Conditions ... All articles on this topic Stay up-to-date! Subscribe to our newsletter. Advertising Free Credit Report Free Psychics Advertisement How Can Mercury Affect Children? Frequently Asked Questions from ATSDR Related Resources Chemical Sensitivities Drug Reaction List Allergy Symptoms Children's Allergies ... Treatment Options Receive Site Updates Subscribe to Newsletter Your Email Address: This section discusses potential health effects from exposures during the period from conception to maturity at 18 years of age in humans. Potential effects on children resulting from exposures of the parents are also considered. Children are at risk of being exposed to metallic mercury that is not safely contained, to mercury that may be brought home on work clothes or tools, or to methylmercury-contaminated foods. Methylmercury eaten or swallowed by a pregnant woman or metallic mercury that enters her body from breathing contaminated air can also pass into the developing child. Inorganic mercury and methylmercury can also pass from a mother's body into breast milk and into a nursing infant.

43. Research Project : Determine If Metal Toxicity Is Related To The Cause And / Or Pink Disease, or acrodynia, very seriously affected thousands of young children between1890 and 1950 5. Aside from the pink integumentary changes, there is http://www.puterakembara.org/archives4/00000010.shtml

Research Project : Determine if metal toxicity is related to the cause and / or symptoms of autism Previous entry: " Overview of Autism Research, Testing and Treatment by Jim Adams - one parent's opinion" Next entry: " ... - In contrast to other non-psychotic psychiatric populations, subjects with obsessive-compulsive disorder (OCD) are more prone to have personality" Reprinted by permission of the author, Prof. Jim Adams Project Summary: Objectives: Determine if metal toxicity is related to the cause and/or symptoms of autism. If a possible link is found, then carry out a double-blind, placebo-controlled study of the effect of removing toxic metals on the symptoms of autism. Experimental Approach Collect a wide variety of medical, dental, psychological, speech, and environmental exposure data on fifty children with autism, their mothers, and a control group. Possibly evaluate the safety and efficacy of the Consensus Detoxification Protocol for Children with Autism, developed at a national workshop in February, 2001. Expected Results The cause of autism is currently unknown. This study will help determine if metal toxicity is a possible cause of some of the cases of autism.

44. The Future Of Children - Sub-Sections Children who were exposed to large amounts of mercury developed a condition calledacrodynia (which means “painful extremities”) weeks or months after http://www.futureofchildren.org/information2827/information_show.htm?doc_id=7097

45. News: About The Dangers Of A Little Mercury... Memory is short. There was a time before the 60's when small children occasionallywere found to have a disease called Pink disease, or acrodynia. http://www.gbg.bonet.se/bwf/eng/news/2001_10/littleMercury.html

On Reality - Images, Experiences, and Distortions Website In Swedish Overview - all pages To Reality ... Links Special Theme: Greenwashing NEWS Oct 25, 2001 About the dangers of a little mercury... In a press-release from PROVE (Parents Requesting Open Vaccine Education), dated October 17, 2001, it's revealed that the CDC (Centers for Disease Control) in the evaluation process of potential links between Thimerosal in vaccines and autism was not as open as it ought to be. According to the press release, the first evaluation of data showed a significantly increased risk, but this evaluation was kept confidential. When data were presented the original data were complemented, and this procedure of complementation rendered the risk assessment inconclusive. A number of lawsuits are going on, where it's claimed that thimerosal in vaccines caused neurological damage to infants, leading to the development of autism. The original data showed an increased risk of a magnitude, that previously has been taken as proof of exposures causing disease, according to the lead attorney in the filed cases, by courts of law in the United States. Conclusive or not-conclusive makes a big difference when stakes are high. Thousands of families, the attorney says, so stakes are high. So far the press release. Thimerosal is a preservative for vaccines and other drugs, such as nasal drops, ointments and drips for ophthalmic use. What makes Thimerosal controversial is its contents of mercury, and the potential neurotoxic effect from this heavy metal. There are other mercury containing preservatives used in drugs, but in vaccines Thimerosal is the substance of choice. The filed lawsuits claim that children with autism, who have participated in the vaccination programs are victims of mercuric neurotoxic effects from Thimerosal in the vaccines. The possible link between Thimerosal and autism is the subject for investigation by the CDC. The outcome of this process will of course be of great importance for what happens in the courts.

46. Acrodynia Related Search acrodynia Begin your search for. acrodynia. acrodynia search Go! Search for otherbooks. All Products. http://www.book-summary.com/acrodynia.html

Acrodynia Begin your search for Acrodynia Acrodynia search Top Books Search for other books All Products Books Popular Music Classical Music Video DVD privacy Free Site Templates About Acrodynia Touching the derivation of the name Acrodynia, I confess myself, with sorrow, equally at fault. Among a multitude of opinions upon this delicate point- some acute, some learned, some sufficiently the reverse I am able to select nothing which ought to be considered satisfactory. Modified text originally written by Edgar Allan Poe.

47. Treatment In the 1940s and 1950s, mercury became known as the product that causedacrodynia, also known as Pink Disease. The manifestations http://www.hgtech.com/HSE/Treratment.htm

Toxicity of Mercury Treatment of Mercury Intoxication Authored by Barry Diner, MD , Chief Resident, Department of Emergency Medicine, The Brooklyn Hospital Center Co-authored by Barry Brenner, MD, PhD , Director, Division of Research, Associate Clinical Professor, Department of Emergency Medicine, Weill College of Medicine, Cornell University, The Brooklyn Hospital Center Barry Diner, MD is a member of the following medical societies: American College of Emergency Physicians Edited by Michelle Ervin, MD , Chair, Department of Emergency Medicine, Howard University Hospital; John T. VanDeVoort, PharmD, ABAT , Clinical Assistant Professor, Pharmacy Manager, Regions Hospital Pharmacy, University of Minnesota College of Pharmacy; Fred Harchelroad, MD , Director, Medical Toxicology Treatment Center, Associate Professor of Emergency Medicine, Department of Emergency Medicine, Allegheny General Hospital; John Halamka, MD , Executive Director, Center for Quality and Value, Instructor, Division of Emergency Medicine, Beth Israel Deaconess Medical Center; and Raymond J. Roberge, MD, MPH

48. HONselect - Peripheral Nervous System Diseases Information about the main diseases of the peripheral nerves external to the brain and spinal cord.Category Health Conditions and Diseases Peripheral Nervous System...... Neuralgia, Neuritis. Peripheral Nervous System Neoplasms, Polyneuropathies.acrodynia, Amyloid Neuropathies. Isaacs Syndrome, Neurofibromatosis 1. http://www.hon.ch/HONselect/Selection/C10.772.html

HONselect: Introduction Search Browse Favourites List of Rare Disease add HONselect Contents on "Peripheral Nervous System Diseases": MeSH hierarchy and definition Research Articles Web resources Medical Images Medical News Medical Conferences Clinical Trials Wondering about the holiday blues! MeSH Hierarchy English French German Spanish Portuguese MeSH Broader term(s) Diseases Nervous System Diseases Neuromuscular Diseases Peripheral Nervous System Diseases MeSH definition Diseases of the peripheral nerves external to the brain and spinal cord, which includes diseases of the nerve roots, ganglia, plexi, autonomic nerves, sensory nerves, and motor nerves. Subheadings : complications / diagnosis / embryology / epidemiology / etiology / metabolism / microbiology / surgery / therapy MeSH Narrow term(s) Brachial Plexus Neuropathies Complex Regional Pain Syndromes Diabetic Neuropathies Guillain-Barre Syndrome Mononeuropathies Nerve Compression Syndromes Neuralgia Neuritis Peripheral Nervous System Neoplasms Polyneuropathies Acrodynia Amyloid Neuropathies Isaacs Syndrome Neurofibromatosis 1 Pain Insensitivity, Congenital

49. Untitled History 1926 Goldberger tried to produce Pellagra in rats, developeda severe dermatitis called acrodynia (painful extremities); http://www.animal.ufl.edu/ans6449/Vitamin B6.htm

Chapter 9 Vitamin B Not a problem for ruminants, horses and adequate for swine and poultry fed typical diets Important human diets, young, pregnant or lactating women Most important for protein metabolism Chemical Structure and Properties Simple structure of 3 substituted pyridine derivatives Alcohol (pyridoxine or pyridoxol) Aldehyde (Pyridoxal) Amine (Pyridoxamine) Equal activity for animals (but not microorganisms) Two coenzyme forms - pyridoxal phosphate (PLP, also codecarboxylase) and pyridoxamine phosphate Various forms interconvertible, most activity PLP B quite stable except to light (especially in neutral or alkaline medium) Supplementation form pyridoxine hydrochloride Antagonist - Deoxypyridoxine, isoniazid, antihypertensive drugs Penicillamine, L-Dopa, oral contraceptives (more estrogen part), antagonist in flax seed Analytical Procedures Biological - rat or chick growth Standard method - microbiological (Saccharomyces uvarum) GLC - Good for pure standards HPLC may eventually be method of choice Metabolism Digestion - splitting from protein Absorption - jejunum, ileum as free forms

50. Untitled Document Xueseng Jiang blind,doctor in charge of a case on massage,one of the first passelof blind doctor in Nanjing Hengyi Ma acrodynia,go by the name of the http://www.njcl.org.cn/english/homepage/renwu.htm

Figure ¡¡Fuxing Luo : blind ,the first blind Undergraduate,engaged ¡¡¡¡¡¡¡¡¡¡¡¡¡¡¡¡ ¡¡¡¡¡¡ in special education. ¡¡Zhuxiang Xu:¡¡deaf-mute,painter. ¡¡Heng Cao:¡¡deaf,advanced engineer. ¡¡Xueseng Jiang:¡¡blind,doctor in charge of a case on massage,one of the first ¡¡¡¡¡¡¡¡¡¡¡¡¡¡¡¡¡¡¡¡¡¡¡¡¡¡¡¡¡¡¡¡¡¡ passel of blind doctor in Nanjing ¡¡Hengyi Ma:¡¡acrodynia,go by the name of "the present age Boer" ¡¡Xiaohua Lu:¡¡acrodynia,professor,doctoral tutor ¡¡Haidong Zhang:¡¡acrodynia, excellent athlete ¡¡Tingting Zhou:¡¡female,blind ,the Nation handicapped self-enhancement exemplar Gminglei spatial station Tel:86-025-7711316 ¡¡Address: 114 Chengxian Street.Nanjing

51. Gail Garrett In addition, toxicological syndromes include erythism and acrodynia. Erythismconsists of personality changes, withdrawal, and loss of selfcontrol. http://wwwchem.csustan.edu/chem4400/sjbr/Garrett.htm

Mercury in Amalgam Fillings Amalgam is the name of the material that dentists use to place a “silver” filling in a tooth. It is composed of approximately 57-46% powder containing silver, tin, and copper and sometimes zinc, palladium, or indium in smaller quantities. This alloy powder is dissolved in approximately 43-54% elemental liquid mercury (United States 1993). Amalgam has been used in the field of dentistry for over 100 years (in varying concentrations). There are approximately 22 million amalgam fillings placed in the teeth of the English and the Welsh per year. In the United States, there are more than 160 million amalgams placed per year. It is used in about 75% of all fillings in these countries (Eley 2001). Amalgam is a self-hardening mixture that once set, must be removed by a high-speed drill. Today, it is mainly used in posterior teeth, usually on occlusal surfaces, as an economical, long-lasting, and durable alternative to tooth-colored filling materials such as composites and porcelain. Amalgam undergoes an initial degradation to form an oxide layer that seals the tooth-restoration interface and prevents bacterial leakage that could infect the pulp of the tooth and lead to its extraction (United States 1993).

52. Nat'l Academies Press, Vitamin Tolerance Of Animals (1987), 9 Vitamin B prolonged, PEP, readily, saturation, action, fibers, passive, adenine, pyridox,microflora, suggested, neuropathol, gests, acrodynia, nerve, weakness, workers http://www.nap.edu/books/030903728X/html/58.html

Pyridoxine) Vitamin Tolerance of Animals Board on Agriculture ( BOA Related Books Openbook Linked Table of Contents Front Matter, pp. i-vi Contents, pp. vii-x Introduction, pp. 1-2 1 Vitamin A, pp. 3-10 2 Vitamin D, pp. 11-22 3 Vitamin E, pp. 23-30 4 Vitamin K, pp. 31-35 5 Ascorbic Acid, pp. 36-42 6 Thiamin, pp. 43-46 7 Niacin, pp. 47-52 8 Riboflavin (Vitamin B ..., pp. 53-57 9 Vitamin B (Pyridoxine..., pp. 58-63 10 Folic Acid, pp. 64-66 11 Pantothenic Acid, pp. 67-69 12 Biotin, pp. 70-73 13 Vitamin B , pp. 74-76 14 Choline, pp. 77-83 15 Research Needs, pp. 84-84 Summary, pp. 85-87 Appendix Table, pp. 88-92 Index, pp. 93-96 THIS PAGE You may want to explore these Related Books Openbook Linked Table of Contents Front Matter, pp. i-vi Contents, pp. vii-x Introduction, pp. 1-2 1 Vitamin A, pp. 3-10 2 Vitamin D, pp. 11-22 3 Vitamin E, pp. 23-30 4 Vitamin K, pp. 31-35 5 Ascorbic Acid, pp. 36-42 6 Thiamin, pp. 43-46 7 Niacin, pp. 47-52 8 Riboflavin (Vitamin B ..., pp. 53-57 9 Vitamin B (Pyridoxine..., pp. 58-63 10 Folic Acid, pp. 64-66 11 Pantothenic Acid, pp. 67-69 12 Biotin, pp. 70-73

53. Nat'l Academies Press, Environmental Medicine: (1995), Case Study 21: Mercury In CASE STUDY 21 MERCURY/acrodynia MERCURY IN HOUSE PAINT AS A CAUSE OF acrodynia*EBeCt Of Therapy With NACe£Y1-D,-PeniCi11amine SHALOM ZARACH HIRSCHMAN, MD http://www.nap.edu/books/0309051401/html/445.html

Environmental Medicine: Integrating a Missing Element into Medical Education Institute of Medicine ( IOM Related Books Openbook Linked Table of Contents Front Matter, pp. i-viii Contents, pp. ix-xii Executive Summary, pp. 1-4 1 Introduction, pp. 5-13 2 Curriculum Content, pp. 14-21 3 Implementation Strategies, pp. 22-43 4 Changing Medical Education, pp. 44-51 5 Concluding Remarks, pp. 52-53 References, pp. 54-58 Appendixes, pp. 59-60 A: Taking an Exposure History, pp. 61-96 B: Medical School Courses and Clerk..., pp. 97-120 C: Case Studies in Environmental Me..., pp. 121-138 Case Study 1: Arsenic Toxicity, pp. 139-163 Case Study 2: Seasonal Arsenic Expo..., pp. 164-167 Case Study 3: Asbestos Toxicity, pp. 168-188 Case Study 4: Benzene Toxicity, pp. 189-207 Case Study 5: Beryllium Toxicity, pp. 208-223 Case Study 6: Cadmium Toxicity, pp. 224-243 Case Study 7: Fetal Death Due to No..., pp. 244-248 Case Study 8: Carbon Tetrachloride ..., pp. 249-266 Case Study 9: Chlordane Toxicity, pp. 267-288 Case Study 10: Chronic Reactive Air..., pp. 289-290 Case Study 11: Chromium Toxicity, pp. 291-311

54. CHERAB: Working On Behalf Of Children's Speech And Language Delays And Disorders In acrodynia, symptoms of sufferers (vs. acrodynia sufferers describe excessive painwhen bumping limbs, numbness, and poor circulation (Farnesworth, 1997). http://www.cherab.org/information/dietaryeffects/mercuryautism.html

Join the Cherab Foundation 's free email support discussion list: For information about communication impairments, see Cherab 's partner informational site, Speechville Express Read more about The Late Talker , a new book for families of children who are late to talk. Mercury Levels and Neurological Conditions Autism: A Unique Type of Mercury Poisoning b. Language and Hearing When speech develops, there may be "specific neuromotor speech disorders," including verbal dyspraxia, a dysfunction in the ability to plan the coordinated movements to produce intelligible sequences of speech sounds, or dysarthria, a weakness or lack of control of the oral musculature" leading to articulation problems (Filipek et al, 1999) In regard to language and auditory phenomena, autism's parallels to mercurialism are striking. Emerging signs of mercury poisoning are dysarthria (defective articulation in speech due to CNS dysfunction) and then auditory disturbance, leading to deafness in very high doses (Clarkson, 1992). In some cases, hearing impairment manifests as an inability to comprehend speech rather than an inability to hear sound (Dales, 1972). Hg poisoning can also result in aphasia, the inability to understand and/or physically express words (Kark et al, 1971). Speech difficulties may arise from "intention tremor, which can be noticeable about the mouth, tongue, face, and head, as well as in the extremities" (Adams et al, 1983).

55. Autism: A Novel Form Of Mercury Poisoning 10/1/00 Primary data derive from victims of contaminated fish (Japan Minamata Disease)or grain (Iraq, Guatemala, Russia); from acrodynia (Pink Disease) induced by http://www.mercola.com/2000/oct/1/autism_mercury.htm

Mercola.com Dr. Joseph Mercola All Health, No Hype FREE Weekly Health Newsletter Your Email Address: Previous Newsletters Issue 173 October 1, 2000 Mammograms Don't Save Lives Exposing Conflicts of Interest at the FDA Autism and Mercury Detoxification Autism: Mercury Poisoning? ... Sue AOL Now Health Resources Complete Nutrition Plan Less Grains / Sugars More Omega 3 More Water ... Recommended Products Autism: a Novel Form of Mercury Poisoning S. Bernard, B.A., A. Enayati, M.S.M.E., L. Redwood, M.S.N., H. Roger, B.A., T. Binstock Sallie Bernard, ARC Research, 14 Commerce Drive, Cranford, NJ 07901 USA, 908.276.6300, fax 908.276.1301 Summary Autism is a syndrome characterized by impairments in social relatedness and communication, repetitive behaviors, abnormal movements, and sensory dysfunction. Recent epidemiological studies suggest that autism may affect 1 in 150 U. S. children. Exposure to mercury can cause immune, sensory, neurological, motor, and behavioral dysfunctions similar to traits defining or associated with autism, and the similarities extend to neuroanatomy, neurotransmitters, and biochemistry.

56. Toxicity, Mercury In the 1940s and 1950s, mercury became known as the product that causedacrodynia, also known as Pink Disease. Manifestations of http://www.vaccinationnews.com/DailyNews/July2002/ToxicityMercury18.htm

Vaccination News Home Page http://www.emedicine.com/emerg/topic813.htm (advertisement) window.open("http://www.emedicine.com/PleaseRegister.html","PleaseRegister","width=265,height=295") Toxicity, Mercury Synonyms, Key Words, and Related Terms: Hg, heavy metal Home Search Contents A-Z Index ... Bibliography We are offering CME for this topic. Click on the GetCME button to take CME (Your first test is Free!) AUTHOR INFORMATION Section 1 of 11 Authored by Barry Diner, MD , Clinical Instructor, Division of Emergency Medicine, University of Alberta Coauthored by Barry Brenner, MD, PhD , Chairman, Department of Emergency of Medicine, Professor, Departments of Emergency Medicine and Internal Medicine, University of Arkansas for Medical Sciences Barry Diner, MD, is a member of the following medical societies: American College of Emergency Physicians Edited by Michelle Ervin, MD , Chair, Department of Emergency Medicine, Howard University Hospital; John T VanDeVoort, PharmD, DABAT

57. Neurotoxicity Syndrome TI Familial mercury intoxication presenting with cardiovascular abnormalitiesand acrodynia. TI Mercury poisoning and acrodynia. AU Sedano,HO. http://www.vaccinationnews.com/Scandals/Mar_15_02/NeurotoxSyndromeLS.htm

Neurotoxicity Syndrome, Mercury - literature search To obtain abstracts where they are available, please go to PubMed Search History * #6 explode 'Mercury-Poisoning-Nervous-System' / all subheadings in MIME,MJME (159 records) Record 1 of 159 in SilverPlatter MEDLINE(R) March Week 1 (2002/03) TI: Mercury pollution in the Tapajos River basin, Amazon: mercury level of head hair and health effects. AU: Harada,-M; Nakanishi,-J; Yasoda,-E; Pinheiro,-M-C; Oikawa,-T; de-Assis-Guimaraes,-G; da-Silva-Cardoso,-B; Kizaki,-T; Ohno,-H SO: Environ-Int. 2001 Oct; 27(4): 285-90 JN: Environment-international IS: 0160-4120 LA: English RO: National-Library-of-Medicine AN: 21542847 Record 2 of 159 in SilverPlatter MEDLINE(R) February Week 2 (2002/02) TI: Microglial reaction induced by noncytotoxic methylmercury treatment leads to neuroprotection via interactions with astrocytes and IL-6 release. AU: Eskes,-Chantra; Honegger,-Paul; Juillerat-Jeanneret,-Lucienne; Monnet-Tschudi,-Florianne SO: Glia. 2002 Jan; 37(1): 43-52

58. Autism A Novel Form Of Mercury Poisoning 5). Primary data derive from victims of contaminated fish (Japan Minamata Disease)or grain (Iraq, Guatemala, Russia); from acrodynia (Pink Disease) induced http://www.whale.to/v/mercury2.html

59. Tandvårdsskadeförbundet - Artikel I TF-bladet Vad ställer amalgamet idag till med? En föreställning om vidden av det helafår man genom att studera sjukdomen som kallades akrodynia (acrodynia). http://www.tf.nu/artiklar/87-3_Akrodynia.html

INFO Ledare Press- nytt Tf - bladet bli Medlem ... Medlemssida Artikel publicerad i TF-bladet 3/1987 AKRODYNIA Kalomel - medicin eller gift? Sjukdomen Akrodynia Symtom Vad orsakades sjukdomen av? "Ny" sjukdom Mats Hanson http://www.tf.nu/

60. THE MERCK MANUAL, Sec. 9, Ch. 105, Disorders Of The Oral Region acrodynia may be caused by a toxic reaction to mercury or by hypersensitivityto various substances; exposure to mercury is now rare. http://www.merck.com/pubs/mmanual/section9/chapter105/105b.htm

This Publication Is Searchable The Merck Manual of Diagnosis and Therapy Section 9. Dental And Oral Disorders Chapter 105. Disorders Of The Oral Region Topics [General] Inflammation Of The Oral Mucosa Neoplasms Inflammation Of The Oral Mucosa Inflammation of the mouth may be caused by infection, systemic disease, or a physical agent. When widespread, it constitutes stomatitis. Bacterial infections: Usually the causative agent is streptococci. Mycobacterium tuberculosis can produce oral ulcers inoculated by sputum from the lungs. Syphilis can produce a primary chancre. If untreated, syphilis may produce secondary mucous patches and a tertiary gumma (see Ch. 164 Neisseria gonorrhea produces burning ulcerations of the gingiva and tongue as well as pharyngitis. Cervicofacial actinomycosis (lumpy jaw) may resemble a fungal infection but is bacterial (see Actinomycosis in Ch. 157). Yellow ("sulfur") granules in purulent exudate are pathognomonic. Noma (gangrenous stomatitis) is a nonspecific, mainly fusospirochetal bacterial infection in which severe, even full-thickness, tissue destruction occurs in a debilitated person. It can be considered an extreme form of acute necrotizing ulcerative gingivitis (see Ch. 106

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