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         Adrenoleukodystrophy:     more books (16)
  1. Peroxisomal Disorders: An entry from Gale's <i>Gale Encyclopedia of Medicine, 3rd ed.</i> by Judith Sims, Teresa Odle, 2006
  2. Lorenzo's oil - more than just a great movie.: An article from: Medical Update

21. Central Nervous System Diseases
Leukodystrophies); About little Joey (Krabbe's Disease) J Johnson Call Again Soon. adrenoleukodystrophy About adrenoleukodystrophy
http://www.mic.ki.se/Diseases/c10.228.html
search help staff
Central Nervous System Diseases
Patients and laypersons looking for guidance among the target sources of this collection of links are strongly advised to review the information retrieved with their professional health care provider.

22. The Contact A Family Directory - ADRENOLEUKODYSTROPHY
printer friendly, adrenoleukodystrophy, adrenoleukodystrophy ALD Schilder'sDisease Sudanophilic Leukodystrophy. adrenoleukodystrophy
http://www.cafamily.org.uk/Direct/a24.html
printer friendly ADRENOLEUKODYSTROPHY home more about us in your area conditions information ... how you can help search this site Adrenoleukodystrophy: ALD: Schilder's Disease: Sudanophilic Leukodystrophy Adrenoleukodystrophy (ALD) is a life threatening genetic disorder which only occurs in males and affects the adrenal gland and white matter of the nervous system. It is caused by the accumulation of long chain fatty acids in the cells and tissues of an affected child. ALD was first recognised in 1923 and since then several hundred cases have been reported from many countries. There are several forms of ALD. In the severe (childhood cerebral) form, boys usually develop normally until they reach between the ages of 4-10 years of age when behavioural changes, such as loss of memory and emotional instability, may be experienced in varying degrees. There may also be difficulty with vision, hearing and motor function. Adrenal function may also be impaired ( Addison Disease ) leading to nausea, vomiting, and changes in skin colour. Addison Disease is commonly associated with gonadotrophin deficiency and may present with failure to enter puberty. There is continuous progressive deterioration of the nervous system. The rate of deterioration varies in each individual child.

23. Lorenzo's Oil - DrGreene.com - Caring For The Next Generation
adrenoleukodystrophy is one of the neurodegenerative diseases of childhood forwhich bone marrow transplantation is most successful. adrenoleukodystrophy.
http://www.drgreene.com/21_13.html
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Adrenoleukodystrophy
What is Adrenoleukodystrophy? Isn’t that what the little boy in the movie “Lorenzo’s Oil” had?
Adrenoleukodystrophy is one of the genetic neurodegenerative disorders . These disorders are grouped into four categories: sphingolipidoses, neuronal ceroid lipofuscinoses, adrenoleukodystrophy (like Lorenzo, whose story is portrayed in the movie “Lorenzo’s Oil”), and sialidosis. These may be distinguished from one another based on head CT, head MRI, nerve conduction velocities, visual evoked potentials, auditory evoked potentials, electroretinography, and to a lesser extent, EEG's.
Adrenoleukodystrophy comes in three types (classic, neonatal, and adrenomyeloneuropathy). In these disorders, the myelin, also known as the white matter, is lost from the nerve cells. The myelin is supposed to be the insulation around the nerve that allows it to transmit electrical impulses properly. Lorenzo's Oil, a dietary supplement, is the most famous treatment, but by no means the only option.

24. Leukodystrophy
2432 Web Site www.ulf.org Email ulf@ceet.niu.edu Index of conditions (listedabove), Information in Spanish, French, German adrenoleukodystrophy fact sheet
http://www.kumc.edu/gec/support/leukodys.html
Leukodystrophy
  • Adrenoleukodystrophy (ALD) Alexanders Disease Canavan Disease (Spongy Degeneration) Cerebrotendinous Xanthomatosis (CTX) Globoid Cell (Krabbes) Leukodystrophy Metachromatic Leukodystrophy (MLD) Neonatal ALD Ovarioleukodystrophy Pelizaeus-Merzbacher Disease Refsum Disease van der Knaap Syndrome Zellweger Syndrome
United Leukodystrophy Foundation 2304 Highland Dr., Sycamore, IL 60178 Phone: 800.728.5483 Fax: 815.895.2432 Web Site: www.ulf.org E-mail: ulf@ceet.niu.edu Index of conditions (listed above), Information in Spanish, French, German Adrenoleukodystrophy fact sheet, Sept 1997, National Institutes of Health, Bethesda, MD Pelizaeus-Merzbacher Support Group 209-211 City Road, London EC1V 1JN Phone: 020 7608 8700 Fax: 020 7608 8701 Minicom 020 7608 8702 Helpline 0808 808 3555 Freephone for parents and families (10am-4pm, Mon-Fri) E-mail: info@cafamily.org.uk
Web Site: www.cafamily.org.uk/Direct/p15.html
Pelizaeus-Merzbacher Disease Support Group Indianapolis, Indiana, E-mail: daviau1@juno.co Newsletter, Annual PMD Family Conference PMD Foundation , (Pelizaeus-Merzbacher Disease), 333 Homestead Avenue, Haddonfield, NJ 08033 Phone: 856.795.1539

25. HealthlinkUSA Adrenoleukodystrophy Links
Wednesday February 5, 2003. The healthy way to search today's best sites.Links to websites which may include treatment, cures, diagnosis
http://www.healthlinkusa.com/461ent.htm

26. Adrenoleukodystrophy; Treatment, Prevention, Cure
adrenoleukodystrophySearch information from many of the best adrenoleukodystrophyhealth sites. Brain Diseases. adrenoleukodystrophy forum/message board.
http://www.healthlinkusa.com/content/461.html
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27. Adrenoleukodystrophy (ALD): A Case Study Using The Film "Lorenzo's Oil"
**Sorry, WWNFF LPT can not answer questions regarding the film Lorenzo'sOil. ** We DO NOT have information on Lorenzo's condition.
http://www.woodrow.org/teachers/bi/1994/adreno.html
**Sorry, WWNFF - LPT can not answer questions regarding the film "Lorenzo's Oil."**
We DO NOT have information on Lorenzo's condition.
You may want to visit
The Internet Movie Database

for more information on the movie.
The information we do have is
here

The Woodrow Wilson National Fellowship Foundation
CN 5281, Princeton NJ 08543-5281 Tel:(609)452-7007 Fax:(609)452-0066

28. 1Up Health > Adrenoleukodystrophy > Causes, Incidence, And Risk Factors Of Adren
Comprehesive information on adrenoleukodystrophy (Melanodermic leukodystrophy,NALD, Neonatal adrenoleukodyrstophy, Xlinked adrenoleukodystrophy).
http://www.1uphealth.com/health/adrenoleukodystrophy_info.html
1Up Health Adrenoleukodystrophy Alternative Medicine Clinical Trials ... Health Topics A-Z Search 1Up Health Adrenoleukodystrophy Information Adrenoleukodystrophy Causes, Incidence, and Risk Factors Alternative names : Melanodermic leukodystrophy, NALD, Neonatal adrenoleukodyrstophy, X-linked adrenoleukodystrophy Definition : Adrenoleukodystrophy describes any of several closely related inheritable disorders of the breakdown ( metabolism ) of certain fats (long chain fatty acid) that affects the adrenal glands , nervous system, and testes
Causes, Incidence, and Risk Factors
Adrenoleukodystrophy is transmitted as an X-linked trait (the neonatal form is by autosomal recessive transmission). Its incidence is estimated at 1 out of 20,000 to 1 in 50,000 and affects all races. The metabolic defect is the accumulation of long chain fatty acids in the nervous system, adrenal gland, and testes , where the accumulated material disrupts normal activity. There are several (seven recognized) different forms of the disease. The neonatal form appears shortly after birth and includes seizures and delayed neurological development with death occurring in infancy or young childhood. The childhood cerebral form (around 4-8 years) appears in mid-childhood, and the other forms appear during

29. 1Up Health > Adrenoleukodystrophy > Causes, Incidence, And Risk Factors Of Adren
adrenoleukodystrophy (ALD) . Read detailed information about adrenoleukodystrophy(ALD) . Includes a set of questions and answers
http://www.1uphealth.com/medical/disease/brain-neurological-disease/adrenoleukod
1Up Health Adrenoleukodystrophy Alternative Medicine Clinical Trials ... Health Topics A-Z Search 1Up Health Adrenoleukodystrophy Information Adrenoleukodystrophy Causes, Incidence, and Risk Factors Alternative names : Melanodermic leukodystrophy, NALD, Neonatal adrenoleukodyrstophy, X-linked adrenoleukodystrophy Definition : Adrenoleukodystrophy describes any of several closely related inheritable disorders of the breakdown ( metabolism ) of certain fats (long chain fatty acid) that affects the adrenal glands , nervous system, and testes
Causes, Incidence, and Risk Factors
Adrenoleukodystrophy is transmitted as an X-linked trait (the neonatal form is by autosomal recessive transmission). Its incidence is estimated at 1 out of 20,000 to 1 in 50,000 and affects all races. The metabolic defect is the accumulation of long chain fatty acids in the nervous system, adrenal gland, and testes , where the accumulated material disrupts normal activity. There are several (seven recognized) different forms of the disease. The neonatal form appears shortly after birth and includes seizures and delayed neurological development with death occurring in infancy or young childhood. The childhood cerebral form (around 4-8 years) appears in mid-childhood, and the other forms appear during

30. ThirdAge - Adam - Adrenoleukodystrophy
adrenoleukodystrophy. Definition Alternative Names Xlinked adrenoleukodystrophy;Melanodermic leukodystrophy; Neonatal adrenoleukodyrstophy; NALD.
http://www.thirdage.com/health/adam/ency/article/001182.htm
document.write(''); document.write(''); document.write('<'); document.write('/SCRIPT>'); document.write(''); document.write(''); document.write('<'); document.write('/A>'); document.write('<'); document.write('/NOSCRIPT>'); document.write('<'); document.write('/IFRAME>'); Activities Computers Family Tree Health ... Prevention
Adrenoleukodystrophy
Definition: Any of several closely related inheritable disorders of the breakdown ( metabolism ) of certain fats (long chain fatty acid) that affects the adrenal glands , nervous system, and testes
Alternative Names: X-linked adrenoleukodystrophy; Melanodermic leukodystrophy; Neonatal adrenoleukodyrstophy; NALD
Causes, incidence, and risk factors: Adrenoleukodystrophy is transmitted as an X-linked trait (the neonatal form is by autosomal recessive transmission). Its incidence is estimated at 1 out of 20,000 to 1 in 50,000 and affects all races. The metabolic defect is the accumulation of long chain fatty acids in the nervous system, adrenal gland, and testes , where the accumulated material disrupts normal activity. There are several (seven recognized) different forms of the disease. The neonatal form appears shortly after birth and includes seizures and delayed neurological development with death occurring in infancy or young childhood. The childhood cerebral form (around 4-8 years), appears in mid-childhood, and the other forms appear during

31. Adrenoleukodystrophy (ALD): A Case Study
adrenoleukodystrophy (ALD) A Case Study Using the Film Lorenzo's Oil . Resources.For more information on adrenoleukodystrophy, please contact
http://www.accessexcellence.org/AE/AEPC/WWC/1994/adreno.html
Using the Film "Lorenzo's Oil"
Adrenoleukodystrophy (ALD):
A Case Study Using the Film
"Lorenzo's Oil"
Linda Gostinger
1994 Woodrow Wilson Biology Institute
Introduction
The purpose of this activity is to expose the students to an inherited genetic disorder by viewing the film "Lorenzo's Oil." The students will be able to learn about this rare disease and follow the progression of the disease from the initial diagnosis through the 32 month ordeal that the family endured. They will experience the frustrations and triumphs with the Odone family as they follow the challenges of finding a cure for ALD. The students will observe the scientific method being put into practice. This is a true-life drama which depicts the social, financial, ethical and political ramifications of a little-known genetic disease that doesn't get much attention from doctors nor the research community. This is an interdisciplinary study that could be used on several levels and with a variety of classes, for example: Biology, Chemistry, Genetics, Ethics, Health, Neurology, Nutrition, Pathology, Psychology and Anatomy.
Summary of the Disease
Adrenoleukodystrophy (ALD) is a rare inherited metabolic disorder characterized by the loss of the fatty covering (myelin sheath) on nerve fibers within the brain and progressive degeneration of the adrenal gland. The basic defect is the impaired capacity to degrade very long chain fatty acids that are found in the blood plasma and tissues of the body. These fatty acids accumulate in the brain (cerebral white matter) and the adrenal glands.

32. Qango : Health: Diseases And Conditions: A: Adrenoleukodystrophy
Home Health Diseases and Conditions A adrenoleukodystrophy,Suggest a Site. Health, etc. If you would like to suggest a site
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33. FSP Syndromes
Adrenomyeloneuropathy l adrenoleukodystrophy protein (ALDP) ; ChromosomeXq28; Recessive Genetics phenotype; Allelic with adrenoleukodystrophy; ?
http://www.neuro.wustl.edu/neuromuscular/spinal/fsp.html

Front
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FAMILIAL SPINAL CORD SYNDROMES
General principles
Familial Spastic Paraplegia ( SPG

Dominant

: Atlastin; 14q11
: Spastin; 2p22
SPG 12q

Recessive

: Paraplegin; 16q24
(Troyer): Spartin; 13q12.3
Infantile onset
: Alsin; 2q33 X-linked : Proteolipid protein; Xq22 Other Familial Spastic Paraplegia +... Ataxia CNS Ocular PNS ... Systemic Disorders Leukodystrophies Adrenomyeloneuropathy : ALDP; Xq28 Adult-onset Krabbe : GalC; 14q31 MLD : Arylsulfatase A; 22q13 Other spinal cord syndromes Syndromes AAA syndrome : Aladin; 12q13 Adrenomyeloneuropathy : ALDP; Xq28 Alexander : GFAP; 17q21 Alzheimer's : Presenilin 1; 14q24 Arnold-Chiari Malformation Cavanagh's Cerebral palsy-Symmetrical Cerebrotendinous xanthomatosis : Cytochrome 450; 2q33 Charlevoix-Saguenay : Sacsin; 13q11 DOPA-responsive dystonias DRPLA : DRPLA protein; 12p13 Episodic ataxia Evans Fitzsimmons syndrome Friedreich ataxia : FRDA; 9q13 Hereditary Motor Syndromes HHH syndrome HMSN 5 : ARX; Xp22 Infections: HTLV-1 Krabbe : GalC; 14q31 L1 cell adhesion molecule (MASA) Lawrence-Moon Leukodystrophy: Adult-onset Mass lesions Mast syndrome Mental retardation Rett syndrome: Small testes : ATRX; Xq13

34. Kennedy Krieger Institute Adrenoleukodystrophy (ALD)
Print this page adrenoleukodystrophy (ALD) adrenoleukodystrophy (ALD) is a rare,genetic disorder characterized by the breakdown or loss of the myelin sheath
http://www.kennedykrieger.org/kki/kki_diag.jsp?pid=1069

35. Kennedy Krieger Institute Adrenoleukodystrophy (ALD)
adrenoleukodystrophy (ALD) adrenoleukodystrophy (ALD) is a rare, genetic disordercharacterized by the breakdown or loss of the myelin sheath surrounding nerve
http://www.kennedykrieger.org/accessible/kki_diag.jsp?pid=1069

36. ClinicalTrials.gov - Linking Patients To Medical Research: Results
Search results for adrenoleukodystrophy ALLFIELDS are shown below. Show alltrials, including those no longer recruiting patients. 5 studies were found.
http://clinicaltrials.gov/search/term=Adrenoleukodystrophy
Home Search Browse Resources ... About Search results for Adrenoleukodystrophy [ALL-FIELDS] are shown below.
Show all trials, including those no longer recruiting patients.
5 studies were found. Recruiting Study of Glyceryl Trierucate and Glyceryl Trioleate (Lorenzo's Oil) Therapy in Male Children with Adrenoleukodystrophy
Condition: Adrenoleukodystrophy Not yet recruiting Study of Bile Acids in Patients With Peroxisomal Disorders
Conditions: Infantile Refsum's Disease; Zellweger Syndrome; Bifunctional Enzyme Deficiency; Adrenoleukodystrophy Recruiting Study of Pulmonary Complications in Pediatric Patients With Storage Disorders Undergoing Allogeneic Hematopoietic Stem Cell Transplantation
Conditions: I Cell Disease; Fucosidosis; Globoid Cell Leukodystrophy; Adrenoleukodystrophy; Mannosidosis; Niemann-Pick Disease; Pulmonary Complications; ... Recruiting Study of Oral Cholic Acid in Patients With Inborn Errors of Bile Acid Synthesis
Conditions: Infantile Refsum's Disease; Zellweger Syndrome; Hyperpipecolic Acidemia; Adrenoleukodystrophy; Peroxisomal Disorders; Cholestasis; ... Recruiting Phase II Study of Allogeneic Bone Marrow or Umbilical Cord Blood Transplantation in Patients With Lysosomal or Peroxisomal Inborn Errors of Metabolism
Conditions: Graft Versus Host Disease; Lysosomal Storage Diseases; Peroxisomal Disorders

37. Adrenoleukodystrophy
HOME adrenoleukodystrophy (AddisonSchilder syndrome, Fanconi-Prader syndrome,Siemerling-Creutzfeldt syndrome, bronze Schilder disease).
http://www.bdid.com/adrenoleukodystrophy.htm

HOME
Adrenoleukodystrophy (Addison-Schilder syndrome, Fanconi-Prader syndrome, Siemerling-Creutzfeldt syndrome, bronze Schilder disease)

38. Adrenoleukodystrophy (ALD)
adrenoleukodystrophy Guide picks. An inherited progressive degenerativemyelin disorder in which fats are not metabolized properly
http://rarediseases.about.com/cs/ald/
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Adrenoleukodystrophy
Guide picks An inherited progressive degenerative myelin disorder in which fats are not metabolized properly, leading to permanent nerve and adrenal gland damage.
Link to feature article
"ALD and Lorenzo's Oil" explains the disease and its treatments, and what new therapies are being explored. Association Europeenne contre les Leucodystrophies Addresses of support groups in France, Switzerland, Belgium, and comprehensive information on the disorder in French. The British Trust for the Myelin Project Facts, research news, support, and links to international support groups. Comitato Italiano Progetto Mielina Information in Italian.

39. Florida State University College Of Medicine Digital Library
adrenoleukodystrophy Patient/Family Resources. Neonatal adrenoleukodystrophy Accessdocument. Miscellaneous adrenoleukodystrophy Patient/Family Resources
http://fsumed-dl.slis.ua.edu/patientinfo/metabolism/inborn/peroxisomal/adrenoleu
Patient/Family Resources by Topic: Metabolic Disorders
Adrenoleukodystrophy Patient/Family Resources
Miscellaneous See also:

40. Florida State University College Of Medicine Digital Library
adrenoleukodystrophy Clinical Resources. adrenoleukodystrophy Access document.CliniWeb Homepage (includes links to targeted PubMed MEDLINE searches)
http://fsumed-dl.slis.ua.edu/clinical/metabolism/inborn/peroxisomal/adrenoleukod
Clinical Resources by Topic: Metabolic Disorders
Adrenoleukodystrophy Clinical Resources
Pediatrics Radiology Pathology Genetics ... Miscellaneous Resources See also:

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