1. Anophthalmos And Orbital Implants anophthalmos And Orbital Implants While it is rare for a person tobe born without an eye, it is unfortunately an all too frequent http://www.asoprs.org/anophthalmos.html

Anophthalmos And Orbital Implants While it is rare for a person to be born without an eye, it is unfortunately an all too frequent occurrence for patients to experience loss of an eye due to trauma, infection or an underlying disease state. The first reported surgical removal of an eye (enucleation) was performed over four centuries ago. It is however, in the last century that the greatest strides have been made in perfecting this surgical procedure. Once an eye is removed it is important that the loss in orbital soft tissue be replaced with a suitable implant to provide normal cosmesis. The search for a well-tolerated orbital implant which gives an excellent appearance as well as good motility has covered the gamut of autogenous and alloplastic materials and implant designs. Almost every conceivable material known to man has been used as an orbital implant including: Magnets, gold, silver, glass, silicone, cartilage, bone, fat, cork, titanium mesh, acrylics, wool, rubber, catgut, peat, agar, asbestos, ivory, cellulose, paraffin, sponge, polyethylene and hydroxyapatite. In addition, a wide variety of implant shapes has been implanted in order to achieve an acceptable cosmetic result including: sphere, sphere with a truncated surface, sphere with a truncated surface and small "knobs projecting from the surface, etc. The most frequent complication associated with the majority of the "older" implants was extrusion of the implant. Other common complications included infection, migration, poor motility, contracted lid fornices and enophthalmos (sunken in appearance). In 1985, hydroxyapatite corraline sphere shaped implants were introduced. Hydroxyapatite is an inert, biocompatible and nontoxic material that has been in use in the medical field for over 15 years. Hydroxyapatite is a calcium phosphate hydroxide compound made up of multiple interconnecting pores. Because this is an inert porous substance, once implanted into the orbit it becomes vascularized and hence an integral part of the orbit. In recent years, porous polyethylene implants have been utilized in a similar fashion

2. EMedicine - Anophthalmos : Article Excerpt By: Nick Mamalis, MD anophthalmos True or primary anophthalmos is very rare. Excerpt from anophthalmos.Please click here to view the full topic text anophthalmos. http://www.emedicine.com/oph/byname/anophthalmos.htm

(advertisement) Excerpt from Anophthalmos Please click here to view the full topic text: Anophthalmos Background: True or primary anophthalmos is very rare. Only when there is complete absence of the ocular tissue within the orbit can the diagnosis of true anophthalmos be made. Extreme microphthalmos is seen more commonly. In this condition, a very small globe is present within the orbital soft tissue, which is not visible on initial examination. Anophthalmia and microphthalmia may occur secondary to the arrest of development of the eye at various stages of growth of the optic vesicle. It is important to recognize microphthalmia because the development of the orbital region, as well as the lids and fornices, is dependent on the presence of a normal-sized eye in utero. Anophthalmia may lead to serious problems in a child, not only due to the absence of a seeing eye, but also due to the secondary disfigurement of the orbit, lids, and eye socket. Early treatment with various expanders or surgery, when necessary, will help decrease the orbital asymmetry and cosmetic deformities in these children. Pathophysiology: Anophthalmia occurs when the neuroectoderm of the primary optic vesicle fails to develop properly from the anterior neural plate of the neural tube during embryological development. The more commonly seen microphthalmia can result from a problem in development of the globe at any stage of growth of the optic vesicle.

3. E-Doc: Anophthalmos Medical Dictionary. anophthalmos http://www.edoc.co.za/medilink/dict/410.html

Medical Dictionary Anophthalmos Congenital absence of a true eyeball. Information last Updated: 1997-06-27 Contact Us E-Doc Send Questions and comments to the Pagemaster HTML by: E-Doc Reprohouse Last updated: 06 October 1999

4. Anophthalmia (anophthalmos) Is A Condition That Means One, Or Both Eyes Didn’t Program Nr 1914 anophthalmosmicrophthalmos spectrum characterization of ophthalmic, systemic and genetic features in a large series. Moorfields Eye Hospital, London, England. anophthalmos (absence of eye) is an extremely rare congenital anomaly occurring in 0.3-0.6/10 000 births. http://www.angelfire.com/mi/microphthalmia/MACSmicroLeaflet.html

Thanks to the gracious contribution from MACS (our sister support group in the United Kingdom), I now have a comprehensive definition leaflet about Anophthalmia, Microphthalmia, and Coloboma for you. THANK YOU MACS! A nophthalmia P rimary anophthalmia is a complete absence of eye tissue due to a failure of the part of the brain that forms the eye. I n secondary anophthalmia the eye starts to develop and for some reason stops, leaving the infant with only residual eye tissue or extremely tiny eyes which can only be seen under close examination. I n degenerative anophthalmia the eye started to form and, for some reason, degenerated. One reason for this occurring could be a lack of blood supply to the eye. T reatment T here is no cure for this condition. Sometimes the child may have other conditions or complications that may require monitoring. Prosthetic eyes can be fitted to the empty eye sockets which can sometimes involve surgery for reasons such as putting implants into the socket to make it easier to fit the prostheses. Prostheses are not just for cosmetic purposes but also help to promote the growth of the eye socket. Conformers, which are a bit like balloons that can be expanded inside the socket, are sometimes used to further encourage the growth of the socket. M icrophthalmia (microphthalmos) is a condition that means the eye(s) started to form during pregnancy but for some reason stopped, leaving the infant with small eyes. The size of the eye can vary from child to child. If very mild, It can almost go unnoticed but is usually

5. Orbital Glial Hamartoma And Anophthalmos In Dandy-Walker Syndrome We report a case of congenital anophthalmos and glial hamartoma in a child with DandyWalker syndrome. http://www.szp.swets.nl/szp/journals/no192107.htm

Neuro-Ophthalmology 1998, Vol.19, No.2, pp. 107-112 © Æolus Press Letters Orbital glial hamartoma and anophthalmos in Dandy-Walker syndrome Lorraine Cassidy , A. Cassels-Brown and A. Soulioti Leeds General Infirmary, Ophthalmology Department, Leeds, England We report a case of congenital anophthalmos and glial hamartoma in a child with Dandy-Walker syndrome. This is the first reported case of anophthalmia and glial hamartoma occurring in conjunction with Dandy-Walker syndrome, and may have some implications with regard to the pathogenesis of this syndrome. Keywords: Anophthalmos , glial hamartoma , Dandy-Walker syndrome .

6. True Anophthalmos a scan on the closed eye lids and diagnosed it as "Primary" or "True" anophthalmos. Is there a possible cure for this? http://med-aapos.bu.edu/publicinfo/store4/TrueAnophthalmos3.37PM.html

True Anophthalmos This question submitted by Sriraman Ganapathi on 8/2/99. My son was born just a week back (July 25, 1999). His eyes were closed completely when he was born. His Lower Eye Lid has gone inside his Upper Eye Lid a little bit on both the eyes. But he has blue bulging on both his lower eye lids that, according to preliminary diagnosis by our PO, looks like a CYST. When the doctor retracted both the eye lids we saw a very small eye. The doctor did a scan on the closed eye lids and diagnosed it as "Primary" or "True" ANOPHTHALMOS. Is there a possible cure for this? If YES, I would like to know where I can go to for a best one. I would also like to know about the possibilities of getting his vision. Thank you August 2nd 1999 Next Article Previous Article Return to Topic Menu Here is a list of responses that have been posted to this article... ANOPHTHALMOS (8/12/99) Anophthalmos (8/10/99) Anophthalmos (8/7/99) If you would like to post a response to this article, fill out this form completely... Please limit the length of the title of the response to 18 characters.

7. Anophthalmos Related Books Search for books related to anophthalmos. anophthalmos info search. Music. Books http://www.geocities.com/generalwordsfour/anophthalmos.html

Anophthalmos info search Music Books Movies Software Begin your search for books related to: Anophthalmos Anophthalmos Book Search Search for other book subjects All Products Books Popular Music Classical Music Video DVD Electronics Audiobooks DVD's Tools FAQ ... privacy For mere reading I suppose one book is pretty much as good as another; but the choice of a desk-book is a more serious matter. It must be neither too thick nor too thin; it must be large enough to make a substantial support; it must be strongly bound so as not to yield or give; it must not be too troublesome to carry backwards and forwards; and it must be about Anophthalmos. These are the conditions which a really good book must fulfil; simple, however, as they are, it is surprising how few volumes comply with them satisfactorily.

8. ASOPRS Site Map Tumors; When an eye is removed anophthalmos and Orbital implants.ASOPRS Foundation. Membership Requirements. ASOPRS Members Only http://www.asoprs.org/sitemap.htm

c Home Members Directory Alabama Arizona ... Sitemap

9. EMedicine - Anophthalmos : Article By Nick Mamalis, MD anophthalmos True or primary anophthalmos is very rare. Only whenthere is complete anophthalmos. Last Updated April 18, 2001, http://www.emedicine.com/oph/topic572.htm

(advertisement) Home Specialties CME PDA ... Patient Education Articles Images CME Patient Education Advanced Search Link to this site Back to: eMedicine Specialties Ophthalmology Globe Anophthalmos Last Updated: April 18, 2001 Rate this Article Email to a Colleague AUTHOR INFORMATION Section 1 of 10 Author Information Introduction Clinical Differentials ... Bibliography Author: Nick Mamalis, MD , Director of Ophthalmic Pathology, Director of Intermountain Ocular Research Center, Professor, Department of Ophthalmology, University of Utah School of Medicine Nick Mamalis, MD, is a member of the following medical societies: American Academy of Ophthalmology American Medical Association American Society of Cataract and Refractive Surgery , and Association for Research in Vision and Ophthalmology Editor(s): Ron W Pelton, MD, PhD , Consulting Staff, Department of Surgery, Memorial Hospital; Donald S Fong, MD, MPH , Assistant Clinical Professor of Ophthalmology, UCLA School of Medicine; Consulting Physician, Department of Ophthalmology, Southern California Permamente Medical Group; Mark T Duffy, MD, PhD

10. ORPHANET® : Anophthalmos Translate this page ORPHANET. ORPHANET database access. anophthalmos.Direct access to details Alias Home Page. http://www.orpha.net/static/GB/anophthalmos_clinical.html

ORPHANET database access Anophthalmos Direct access to details Alias : Home Page

11. Service Page - Pathologie Information DISEASE anophthalmos, clinical, True or primary anophthalmos is alwaysassociated with major brain defects incompatible with life. http://www.orpha.net/consor/cgi-bin/OC_Exp.php?Lng=GB&Expert=1098

12. Anophthalmia/Anophthalmos HOME Anophthalmia/anophthalmos. anophthalmos, clinical; anophthalmos, clinical;Nanophthalmia; Anophthalmia and microphthalmia the search for an answer; http://www.bdid.com/anophthalmia.htm

HOME Anophthalmia/Anophthalmos ANOPHTHALMOS, TRUE OR PRIMARY International Children's Anophthalmia Network Clinical (Microphthalmia/Microphthalmos/Nanophthalmia/Nanophthalmos, Autosomal Recessive) Microphthalmia, Anophthalmia and other related eye disorders Steven has microphthalmia (small eye), partial aniridia (absence of iris) and retinal coloboma (closure defects) No Title Available - "sonar" information Status of Pesticides in Registration, Reregistration... - "sonar" information Anophthalmos-microphthalmos spectrum: characterization of ophthalmic, systemic and genetic features in a large series Microphthalmos Franchesca has anophthalmia Microphthalmia and Anophthalmia - this has a message board for other parents. here is the real important information on the site re: environmental pollutants - at the bottom of the page there are some links to pesticide information Anophthalmia/Microphthalmia - chat site for parents and people with these conditions International Children's Anophthalmia Network A public forum for questions - about microphthalmia and other optic conditions PubMed medline query - this is a page which has some links to environmental effects/microphthalmos, but you have to pay for the reports...

13. ANOPHTHALMOS anophthalmos. This response submitted by RW Enzenauer, MD on 8/12/99. http://med-aapos.bu.edu/publicinfo/store4/ANOPHTHALMOS6.14PM.html

ANOPHTHALMOS This response submitted by RW Enzenauer, MD on 8/12/99. talk to your pediatric ophthalmologist soon. True anonphthalmos is a embryologic malformation like Dr. Cruz described where the development is arrested very earlier in gestation. The fact that there are some identifiable ocular structures just confirms that the eyes tried to develop. Virtually all of the children have no visual potential at all. If fact, most of the time the effort is at using conformers and scleral schells to promote growth of the orbit and improve the appearance. Robert W. Enzenauer, MD Pediatric Ophthalmology Chattanooga,, TN Previous Article Return to Main Article Article complete. Click HERE to return to the Public Information Menu.

14. Waardenburg Syndrome Mental Retardation Syndrome, Crooked Fingers Syndrome, KleinWaaardenburg Syndrome,Ophthalmo Acromelic Syndrome, Syndactyly-anophthalmos Syndrome, Waardenburg http://www.bdid.com/waardenburg.htm

HOME Waardenburg Syndrome (Mende Syndrome, Ptosis-Epicanthus Syndrome, Van der Hoeve Halbertsma Waardenburg Gualdi Syndrome) Waardenburg Syndrome Waardenburg Syndromes Waardenberg syndrome Waardenberg syndrome ... Support Group Pierpont Type Waardenburg type pierpont Type I Waardenburg syndrome type 1 Waardenburg Syndrome WAARDENBURG SYNDROME, TYPE I; WS1 Type II Waardenburg Syndrome Waardenburg syndrome type 2 Type IIa Waardenburg syndrome type 2a WAARDENBURG SYNDROME, TYPE IIA; WS2A Type IIb Waardenburg syndrome type 2b WAARDENBURG SYNDROME, TYPE IIB; WS2B with Ocular Albinism Autosomal Recessive See Albinism, Ocular, with Sensorineural Deafness Type III (Anophthalmia-Hand-Foot Defects-Mental Retardation Syndrome, Crooked Fingers Syndrome, Klein-Waaardenburg Syndrome, Ophthalmo Acromelic Syndrome, Syndactyly-Anophthalmos Syndrome, Waardenburg-(Recessive) Anophthalmia Syndrome) Klein-Waardenburg syndrome Anophthalmia waardenburg syndrome WAARDENBURG SYNDROMES ophthalmo-acromelic syndrome ... ANOPHTHALMOS WITH LIMB ANOMALIES Type IV (Waardenburg Syndrome with Hirschsprung Disease; Waardenburg Syndrome, Variant; Hirschsprung Disease with Pigmentary Anomaly; Waardenburg-Shah Syndrome) Waardenburg Syndrome Waardenburg syndrome, type 4

15. Www.nlm.nih.gov/cgi/mesh/2K/MB_cgi?term=Anophthalmos Similar pages Syndrome DB Table of Contents Wilms tumor-gonadoblastoma syndrome anophthalmia-hand-foot defects-mental retardationsyndrome anophthalmia-Waardenburg syndrome anophthalmos-limb anomalies http://www.nlm.nih.gov/cgi/mesh/2K/MB_cgi?term=Anophthalmos

16. Anophthalmos anophthalmos. MVC003S.JPG MVC-003S.JPG, MVC-004S.JPG MVC-004S.JPG. http://www.irak.be/ned/missies/anophthalmos/page_01.htm

Anophthalmos MVC-003S.JPG MVC-004S.JPG

17. 1914: Anophthalmos-microphthalmos Spectrum: Characterization Of Ophthalmic, Syst Program Nr 1914 anophthalmosmicrophthalmos spectrum characterizationof ophthalmic, systemic and genetic features in a large series. http://www.faseb.org/genetics/ashg99/f1914.htm

Program Nr: 1914 Anophthalmos-microphthalmos spectrum: characterization of ophthalmic, systemic and genetic features in a large series. N.K. Ragge, A.J. Vivian, R.B. Jones, J.R. Collin. Moorfields Eye Hospital, London, England. Anophthalmos (absence of eye) is an extremely rare congenital anomaly occurring in 0.3-0.6/10,000 births. We reviewed 83 cases of anophthalmos (or extreme microphthalmic remnant), characterising the ocular, systemic and genetic features. Systemic findings included: cleft lip and palate, preauricular skin tags, facial clefting, dysplastic kidneys, corpus callosal dysgenesis, Delleman's syndrome, CHARGE, skin loss over chest wall, and branchio-oculo-facial syndrome. Possible etiologies included gestational exposure to varicella, carbamazepine and i.v. drug abuse. Autosomal recessive inheritance was implied in five cases which were the product of consanguinous marriages. One case had a strong family history of Waardenburg's syndrome. Seven cases had a family history of developmental eye anomalies or early onset blindness and 13 cases had a family history of relevant systemic features, such as deafness or cleft palate. The case with brachio-oculo-facial syndrome had an affected sibling and a cousin with 'cat-eye' phenotype. Only one case was known to have a chromosome anomaly - a Turner's mosaic. Seven families had a history of miscarriage. This series adds significantly to the world literature on anophthalmos and further clinical and genetic analysis may provide clues to the developmental ocular genetic process.

18. 806: Clinical Features Of Four Males And An Obligate Carrier In A Family With Le Clinical features include anophthalmos or microphthalmos, microcephaly, mental retardation,external ear, digital, cardiac, skeletal, and urogenital anomalies http://www.faseb.org/genetics/ashg99/f806.htm

Program Nr: 806 Clinical Features of Four Males and an Obligate Carrier in a Family with Lenz Syndrome. S. Forrester , S. Rothert , R. Urban , M. Kovach , V. Kimonis 1) Department of Pediatrics, SIU School of Medicine, Springfield, IL; 2) Department of Ophthalmology, Tampa General Hospital, Tampa, FL. rd toes bilaterally and dysplastic ears. We believe this family will add to the spectrum of clinical features of Lenz syndrome. Many of the cases published to date for Lenz syndrome are isolated reports. Linkage analysis in this family is in progress to identify the gene responsible for Lenz syndrome.

19. Analysis Of Anophthalmos 1 (with Mental Retardation, Without Limb Analysis of anophthalmos 1 (with mental retardation, without limb anomaliesor dental or urogenital abnormalities), G2D Home. GO TO http://www.bork.embl-heidelberg.de/g2d/exam_disease.pl?U289

20. MeSH-D Terms Associated To MeSH-C Term Anophthalmos MeSHD terms associated to MeSH-C term anophthalmos, G2D Home. The number indicatesthe strength of the association of the corresponding term to anophthalmos. http://www.bork.embl-heidelberg.de/g2d/c2d.pl?Anophthalmos:unknown

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