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         Bovine Spongiform Encephalopathy:     more books (100)
  1. One year later, still looking to resolve BSE issues.(Bovine spongiform encephalopathy): An article from: Pro Farmer
  2. FAO says better controls and surveillance needed to protect consumers from BSE.(Food and Agriculture Organization)(Bovine Spongiform Encephalopathy (Mad ... An article from: Food & Drink Weekly
  3. Johann's announces BSE roundtable; lays out impacts of closed border.(Mike Johanns)(Bovine spongiform encephalopathy): An article from: Food & Drink Weekly
  4. Veneman says more U.S. cases of BSE; FDA's BSE safety rules to be released later this month.(Bovine spongiform encephalopathy, Food and Drug Administration): An article from: Food & Drink Weekly
  5. Bovine Diseases: Cowpox, Bluetongue Disease, Anthrax, Q Fever, Bovine Spongiform Encephalopathy, Foot-And-Mouth Disease, Leptospirosis, Bloat
  6. Latest Canadian BSE discovery puts border opening in jeopardy.(Bovine spongiform encephalopathy): An article from: Food & Drink Weekly
  7. 21st Century Complete Guide to Bovine Spongiform Encephalopathy (BSE) - Mad Cow Disease by U.S. Department of Agriculture USDA, 2003-12-29
  8. Alberta Selects TeSeE BSE Test.(Bovine Spongiform Encephalopathy)(Brief Article): An article from: Food Ingredient News
  9. Market reaction to new Canadian BSE case fairly muted.(Bovine Spongiform Encephalopathy): An article from: Food & Drink Weekly by Gale Reference Team, 2005-01-10
  10. Mad cow mania: the ultimate fallout from the first case of BSE in the United States remains uncertain.(bovine spongiform encephalopathy (BSE)): An article from: Dairy Today by Steve Cornett, Jim Dickrell, et all 2004-01-01
  11. Bovine Spongiform Encephalopathy (BSE) or Mad Cow Disease
  12. Review of the USDA's Bovine Spongiform Encephalopathy Response: Hearing Before the Committee on Agriculture, House of Representatives, One Hundred Eig by United States, 2004-01
  13. USDA ends BSE investigation with no further discoveries.(United States Department of Agriculture)(Bovine Spongiform Encephalopathy): An article from: Food & Drink Weekly
  14. BSE ("mad cow disease"): a brief overview.(bovine spongiform encephalopathy)(Report): An article from: Congressional Research Service (CRS) Reports and Issue Briefs by Geoffrey S. Becker, 2005-12-01

41. Bovine Spongiform Encephalopathy
bovine spongiform encephalopathy up. Related topics Bovine spongiformencephalopathy, Published on the Web by the Food and Agriculture
http://agrifor.ac.uk/browse/cabi/detail/2122455b9470c75af1d503ff14a55d33.html
bovine spongiform encephalopathy [up]
Related topics: broader cattle diseases prion diseases
Bovine spongiform encephalopathy
Published on the Web by the Food and Agriculture Organization (FAO), this report was written in 1993 by Richard H. Kimberlin of the Scrapie and Related Diseases Advisory Service (SARAD), Edinburgh. This report provides an introduction to BSE, and outlines its geographical distribution, economic implications, aetiology, epidemiology, clinical signs, pathology, diagnosis, prevention, and control and eradication. A list of references is provided, and the report is in HTML format. Food and Agriculture Organization bovine spongiform encephalopathy infectious diseases prion diseases ... Bovine spongiform encephalopathy (BSE) Written and published on the Web by the United States Department of Agriculture's (USDA's) Animal and Plant Health Inspection Service (APHIS), this site provides information on BSE and other Transmissible Spongiform Encephalopathies (TSE's), including Creutzfeldt-Jakob disease. Information is provided on a variety of BSE and TSE related topics, including BSE in the UK, BSE in the USA, Clinical Signs of BSE, Diagnosis of BSE, scrapie, and chronic wasting disease (CWD) of deer and elk. Some of these documents are in PDF format and can be viewed using Adobe Acrobat Reader. A bovine spongiform encephalopathy (BSE) response plan summary prepared by APHIS and the Food Safety and Inspection Service (FSIS) is available in PDF format.

42. ‹ŠC–ȏó”]ÇiBSEj‚̃y[ƒW(Bovine Spongiform Encephalopathy (B
bovine spongiform encephalopathy ( BSE ). WWW Site. WHO TransmissibleSpongiform Encephalopathies (TSE) OIE bovine spongiform encephalopathy.
http://niah.naro.affrc.go.jp/disease/bse/bse-s.html
‹ŠC–ȏó”]Ç iBSEj‚̃y[ƒW
Last updated 2003/3/28 English
y z y Œú¶˜J“­Èu‹ŠC–ȏó”]ÇiBSEjŠÖŒWvƒz[ƒ€ƒy[ƒW z
‹ŠC–ȏó”]Ç-Bovine Spongiform Encephalopathy ( BSE )
y¶ŽÊ^z‹ŠC–ȏó”]Çi‹¶‹•aj‚̈ê—ái‰p‘j Michael Greger
y’†‰›‹y‚щEŽÊ^zBSEœëŠ³‹‚̉„‘B_Œo×–E‹y‚ÑŽüˆÍ‚̐_Œo–Ô‚É‹ó–E‚ªŒ©‚ç‚ê‚éB ƒAƒXƒgƒƒTƒCƒgiŽüˆÍ‚̏¬‚³‚ÈŠjj‚ª‘B‚µ‚Ä‚¢‚éBˆÍŠÇ«×–EZ“™‚̉ŠÇ”½‰ž‚Í‚È‚¢B ’†‰›x100,‰Ex200
”]Þ—¿‚Ì•…”sE•Ï”s‚ªˆÙíƒvƒŠƒIƒ“’`”’Ž¿(PrP Sc )‚ÌŒŸo‚É‹y‚Ú‚·‰e‹¿
‹“`’B«ŠC–ȏó”]ÇiBovine Spongiform EncephalopathyF‚a‚r‚dj‚Ì”­¶‚Æ“®•¨‰q¶Œ¤‹†Š‚̑Ήž i•½¬‚P‚R”N‚P‚OŒŽ‚Q‚Q“ú) ‹ŠC–ȏó”]ÇiBSE)ƒT[ƒxƒCƒ‰ƒ“ƒXŽ–‹Æ‚Æ“®•¨‰q¶Œ¤‹†Ši2001/10/5XVj
“®•¨‰q¶Œ¤‹†Š‚Ì‹ŠC–ȏó”]ÇCƒvƒŠƒIƒ“CƒXƒNƒŒƒCƒs[‚È‚Ç‚ÌŒ¤‹†‚ÌŒoˆÜ‚ÆŠÖ˜A‹ÆÑ
  • “®•¨‰q¶Œ¤‹†Š‚É‚¨‚¯‚é“`’B«ŠC–ȏó”]ÇŒ¤‹†‚ÌŒoˆÜ (Last updated 26 July, 2001)
  • 43. Bovine Spongiform Encephalopathy (BSE):i‰¼–ójINDEX
    bovine spongiform encephalopathy (BSE) ()INDEX. Last updatedMar 11, 1997 www@niah.affrc.go.jp Dr. J Ralph Blanchfield
    http://niah.naro.affrc.go.jp/disease/bse/ifst/ifst.html
    Bovine Spongiform Encephalopathy (BSE): i‰¼–ójINDEX Last updated Mar 11, 1997 www@niah.affrc.go.jp
    ³Šm‚ðŠú‚·‚½‚ß‚ÉŒ´•¶ŒfÚ‚µ‚Ü‚·‚Ì‚ÅŽŸ‚ð‚²——‚­‚¾‚³‚¢B BSE‚Ö–ß‚é

    44. MEL: Bovine Spongiform Encephalopathy (BSE) Or "Mad Cow Disease"
    bovine spongiform encephalopathy (BSE) or Mad Cow Disease . USDA APHIS BovineSpongiform Encephalopathy (BSE); What the Heck is Mad Cow Disease?
    http://mel.lib.mi.us/health/health-BSE.html

    Michigan.gov Home
    HAL Home MeL Internet MeL Magazines and eBooks Health Information Resources About the Health Collection Back to the Health Index Medline Evaluating Health Information ... Michigan Health and Hospitals
    Bovine Spongiform Encephalopathy (BSE) or "Mad Cow Disease"

    45. CAHP: BSE Information
    bovine spongiform encephalopathy (BSE) Mad Cow Disease. This siteaims to provide information about the BSE situation. We have
    http://cahpwww.vet.upenn.edu/bse/bseinfo.html
    Center for Animal Health and Productivity CAHPWWW Field Investigation BSE Search
    Bovine Spongiform Encephalopathy (BSE)
    [Mad Cow Disease]
    This site aims to provide information about the BSE situation. We have chosen to feature primary sources and other reports that we find well-founded. BSE is, however, a controversial issue with many various view points. We will try to include as many links as possible so that you will be able to reach your own conclusions.
    Bulletins from the CAHP Field Investigation Unit
    BSE Epidemic
    Creutzfeld-Jakob Disease (CJD)
    Background Information
    More sources of information
    Content questions? Dr. Tom Parsons:

    46. Food Standards Australia New Zealand: Proposal P238 - Bovine Spongiform Encephal
    Supporting documentation. Proposal P238 bovine spongiform encephalopathy(BSE). Final Assessment Report - 18 December 20002 pdf 914kb html .
    http://www.anzfa.gov.au/standardsdevelopment/proposals/proposalp238bovinespongif
    Standards Development

    47. Www.foodsafety.gov - Bovine Spongiform Encephalopathy
    bovine spongiform encephalopathy Mad Cow Disease Federal GovernmentWeb Sites. BSE Documents (APHIS) TSEs, CreutzfeldtJakob Disease
    http://www.foodsafety.gov/~fsg/bse.html
    Bovine Spongiform Encephalopathy
    "Mad Cow Disease" Federal Government Web Sites
    International Web Sites State and Local Government Web Sites
    Additional links
    to federal, state and local government agencies. www.FoodSafety.gov Privacy Accessibility Webmaster

    48. Bovine Spongiform Encephalopathy
    bovine spongiform encephalopathy up. Related topics other, nervoussystem diseases. bovine spongiform encephalopathy, Published on
    http://vetgate.ac.uk/browse/cabi/detail/2122455b9470c75af1d503ff14a55d33.html
    bovine spongiform encephalopathy [up]
    Related topics: broader cattle diseases prion diseases spongiform encephalopathy other nervous system diseases
    Bovine spongiform encephalopathy
    Published on the Web in November 2001 by the Veterinary Services division of the US Animal and Plant Health Inspection Service (APHIS). This fact sheet provides information on bovine spongiform encephalopathy (BSE), a chronic degenerative disease affecting the central nervous system of cattle. Information is provided on the history of BSE, clinical signs, epidemiology, related diseases, and the USDA actions in response to BSE. USA bovine spongiform encephalopathy disease control Bovine spongiform encephalopathy Published on the Web by the Office International des Epizooties (OIE) this fact sheet was updated in April 2002 and provides information on Bovine spongiform encephalopathy (BSE), covering aetiology, epidemiology, diagnosis, and prevention and control. References and links to other information sources are available. Office International des Epizooties bovine spongiform encephalopathy cattle diseases Bovine spongiform encephalopathy Published on the Web by the Food and Agriculture Organization (FAO), this report was written in 1993 by Richard H. Kimberlin of the Scrapie and Related Diseases Advisory Service (SARAD), Edinburgh. This report provides an introduction to BSE, and outlines its geographical distribution, economic implications, aetiology, epidemiology, clinical signs, pathology, diagnosis, prevention, and control and eradication. A list of references is provided and the report is in HTML.

    49. Mad Cow Disease Or Bovine Spongiform Encephalopathy (BSE) In Europe - Travel Med
    Health Canada is aware of travellers' concerns about recent reports of domesticanimal cases of mad cow disease or bovine spongiform encephalopathy (BSE) in
    http://www.hc-sc.gc.ca/pphb-dgspsp/tmp-pmv/2001/bse_e.html
    Travel Health Advisory Mad Cow Disease or Bovine Spongiform Encephalopathy (BSE) in Europe Health Canada is aware of travellers' concerns about recent reports of domestic animal cases of mad cow disease or bovine spongiform encephalopathy (BSE) in Europe. BSE is a fatal degenerative illness that affects the central nervous system of cattle. It is part of a family of diseases known as transmissible spongiform encephalopathies, or TSEs, whose different forms affect different species of animals. All TSEs are believed to be linked to an abnormal form of a protein known as a prion. A build-up of this abnormal protein leads to a sponge-like appearance of the affected brain, causing neurological illness and eventual death. Diagnosis of BSE, not possible in live animals, can only be done by examining an animal's brain after death. A human form of TSE was first diagnosed in the 1920s and was named Creutzfeld-Jacob disease (CJD) after the two German scientists who described the illness. Classical CJD (cCJD) occurs naturally in the population at a rate of approximately one person per million individuals per year, making it extremely rare. On average, 30 Canadians will be diagnosed with cCJD each year, with an average age of 60 years. There is no known cure for the disease. In the early 1990s, British researchers noted a new illness having many of the classical CJD symptoms, but with several unique characteristics. Most notably, the emerging illness affected people in their late 20s. In 1996, researchers confirmed a new variant of CJD, now called vCJD. The cause of vCJD appears to be the consumption of beef and beef products from cattle infected with BSE. Following this discovery, strict measures were put in place in the UK and elsewhere to control the spread of BSE among cattle and to minimize the risk to human and animal health.

    50. Srb91-05
    bovine spongiform encephalopathy. NAL call number 470 SC12 DESCRIPTORSbovine spongiform encephalopathy (BSE), review, issues.
    http://www.nal.usda.gov/awic/pubs/oldbib/srb91-05.htm
    ISSN: 1052-536X
    BOVINE SPONGIFORM ENCEPHALOPATHY
    Provided by the Animal Welfare Information Center
    United States Department of Agriculture
    National Agricultural Library
    United States Department of Agriculture
    National Agricultural Library
    Beltsville, Maryland 20705
    SRB 91-05
    Special Reference Briefs
    Janice C. Swanson
    Animal Welfare Information Center
    December 1990
    National Agricultural Library Cataloging Record: Swanson, Janice C. Bovine spongiform encephalopathy (Special reference briefs ; 91-05) 1. Cattle Diseases Bibliography. I. Title. aS21.D27S64 no.91-05 TABLE OF CONTENTS Introduction General and Review Articles ............................. 1 Epidemiology and Diagnoses .............................. 48 Transmission ............................................ 76 ... Author Index INTRODUCTION The first observation of bovine spongiform encephalopathy (BSE) is estimated to have occurred in Great Britain in April of 1985. A specific diagnosis was arrived at in 1986. By June of 1990 there were 14,324 confirmed cases out of an estimated population of 10 million cattle in Great Britain (2, 22, 23, 104). Other cases have been reported in Ireland and Oman in 1989 and 1990, respectively (22, 23, 62, 52).

    51. Bovine Spongiform Encephalopathy
    bovine spongiform encephalopathy, Transmissible Spongiform Encephalopathies,Chronic Wasting Disease. Animal Welfare Information
    http://www.nal.usda.gov/awic/news/bse/bse.htm
    Bovine Spongiform Encephalopathy
    Transmissible Spongiform Encephalopathies,
    Chronic Wasting Disease
    Animal Welfare Information Center
    United States Department of Agriculture
    Agricultural Research Service
    National Agricultural Library

    52. Bmj.com Page Not Found
    Similar pages bovine spongiform encephalopathybovine spongiform encephalopathy back to keyword index. Politics ofGM food risk, science and public trust, A researchbased analysis
    http://www.bmj.com/bmj/bse.htm

    Home
    Help Search/Archive Feedback
    File Not Found ...yet
    The requested URL was not found. Note (added 5 June 98): We have received a lot of missing page requests for URLs which start http://www.bmj.com/bmj/archive... To get to these pages on the new site simply remove the "bmj" in the middle of the URL. Example: http://www.bmj.com/bmj/archive/6991ed2.htm becomes http://www.bmj.com/archive/6991ed2.htm In putting together this site, we have gathered content from a number of different locations. Links from one area to another may not all work. Please take a look at a note from the HighWire developers to get an insight of what work has happened to bring together the site you see now (and why you might be getting this File Not Found page). We have tried to preserve as many old link locations from the previous site as possible, but things fall through the cracks. We will endeavor to repair links if you would bring to our attention via the Feedback page the URL of the page you were trying to access. If you have received this error by trying to use an outdated bookmark , please use the Search/Browse page to re-locate the page of interest.

    53. Australia's Response To Bovine Spongiform Encephalopathy (BSE) In Animals, Commo
    on measures taken by the Commonwealth Government to protect the health of the Australianpublic in response to bovine spongiform encephalopathy (BSE) in animals
    http://www.health.gov.au/pubhlth/strateg/bse/
    This site uses Javascript for its navigation, if you have javascript turned off please use the buttons on the left hand side of the page. Please select a topic from list... Alcohol Australia's Biosecurity Health Response Bovine Spongiform Encephalopathy (BSE) Bowel Cancer Screening Pilot Breastfeeding BreatScreen Australia Cervical Screening Program National Child Nutrition Program Communicable Diseases National Comorbidity Project Disaster Medicine Unit Environmental Health Falls Prevention for Older People Initiative Folate Food Policy Group Health Inequalities Research Collaboration (HIRC) Hepatitis C HIV/AIDS Immunise Australia Program Injury Prevention JETACAR National Drug Strategy National Illicit Drug Strategy (Tough on Drugs) National Health Strategy Papers Physical Activity Pituitary Hormone Initiatives Population Health Social Marketing Promoting Healthy Weight Tobacco
    Australia's Response to
    Bovine Spongiform Encephalopathy (BSE) in animals,
    commonly known as "Mad Cow Disease"
    and its links to Variant Creutzfeldt-Jakob Disease (vCJD)
    Latest News
    Draft Variant Creutzfeldt-Jakob Disease(vCJD) Family Support Response Plan How Australia will Respond to our First Case of vCJD: A Guide for the Public (pdf file 38Kb) Welcome to the website detailing Australia's health response to Bovine Spongiform Encephalopathy (BSE) and its links to variant Creutzfeldt-Jakob Disease (vCJD).

    54. Free Of Mad Cow Disease
    bovine spongiform encephalopathy (Mad Cow Disease). bovine spongiform encephalopathy(Mad Cow Disease) PPA (Phenylpropanolamine) Information Be Smart Click Here.
    http://www.nspcentral.com/madcow.htm
    NSPCentral.com
    The Herb Specialist
    Nature's Sunshine Products Are Guaranteed to Be Free of
    Mad Cow Disease (BSE) Because of NSP's long-standing commitment to superior quality, our consumers may rest assured that all of our products are free of Mad Cow Disease. NSP has taken steps to protect our customers from this anathema for nearly a decade. As an additional proactive measure to ensure safe products, NSP has obtained a written guarantee from each of our bovine material suppliers that the materials are free from disease. All bovine raw materials used in our products are sourced exclusively from countries deemed by U.S. regulatory authorities to be "BSE-free." Our gelatin products, including the capsules that encase many of our products, are especially safe from contamination. In addition to the above precautions, we ensure that gelatin of bovine origin we procure has been specially processed at temperatures and pH levels that denature the proteinaceous prions that transmit the disease, should they somehow be present. Ed Corlett, of the USDA Animal and Plant Health Inspection Service Public Affairs Office, said of Nature's Sunshine Products, "Companies like yours, that take proactive measures to keep the public safe, will prevent the spread of BSE."

    55. Foot And Mouth Disease Information Page
    An overview of bovine spongiform encephalopathy bovine spongiform encephalopathyis a disease of adult cattle affecting the central nervous system.
    http://ianrhome.unl.edu/inthenews/bse.shtml
    IANR Home IANR News Home Headlines World Ag News ... U.K. Info Bovine spongiform encephalopathy BSE information sites NebFact on BSE Guarding Against Contagious Livestock Diseases from Farm Visitors Audio Information about BSE ... Reporting Foot and Mouth and "Mad Cow" Diseases in Livestock: A Primer for Nebraska Media More Topics Confronting the possibilities of agroterrorism: resources Foot-and-mouth disease
    An overview of bovine spongiform encephalopathy
    Key information about BSE Disease statistics for Great Britain Number of reported cases worldwide , excluding the United Kingdom Responses to BSE by governmental agencies David R. Smith, DVM, Ph.D, Extension Beef/ Dairy Veterinarian
    What is BSE?

    56. CJD/BSE Creutzfeldt-Jakob Disease/Bovine Spongiform Encephalopathy
    CREUTZFELDTJAKOB DISEASE (CJD) bovine spongiform encephalopathy (BSE).
    http://www.doh.gov.uk/cjd/cmo96_1.htm
    BOVINE SPONGIFORM ENCEPHALOPATHY (BSE) Go back to referring page Main Page
    20th March 1996 - CEM/CMO/96/1 MESSAGE FROM SIR KENNETH CALMAN, CHIEF MEDICAL OFFICER
    A NEW VARIANT OF CJD
    A statement has been made today in the Houses of Parliament about a new variant of CJD and the possibility that this is linked to BSE exposure before the specified bovine offal (SBO) ban in 1989. GPs and public health physicians in particular are likely to receive requests for information and advice. This brief note is designed to help you respond. Creutzfeldt-Jakob Disease (CJD) is a rare neurological disease, first described in the 1920s and found worldwide. It usually presents in late middle-age with progressive dementia, and is usually fatal within 6 months. It is characterised by spongiform changes in the brain, but this can only readily be diagnosed at post mortem. CJD occurs worldwide at an annual incidence rate of 0.5-1 per million per annum. In view of concerns that BSE could possibly be transmissible to man, the CJD Surveillance Unit was set up in 1990 to monitor the incidence of disease in the UK. To date, the UK annual incidence remains within expected limits - in 1994 the incidence was 0.92 per million and the provisional figure for 1995 is 0.64 per million.

    57. Bovine Spongiform Encephalopathy (BSE-"Mad Cow Disease")
    bovine spongiform encephalopathy ( BSE ) IN JAPAN confirmed. Questionsand Answers About bovine spongiform encephalopathy ( BSE).
    http://ss.niah.affrc.go.jp/disease/bse/bse.html
    Welcome to the National Institute of Animal Health(Japan)
    Japanese
    (Last updated 3 Feb, 2003) www@niah.affrc.go.jp
    Bovine Spongiform Encephalopathy ( BSE ) IN JAPAN: confirmed
    [Source: OIE Disease Information]
    Information received on 10 Sep 2001 from Dr Shigeo Miyajima, Director of Animal Health Division, Ministry of Agriculture, Forestry and Fisheries, Tokyo:
    A 5-year-old Holstein cow kept on a dairy farm in Chiba prefecture was slaughtered on 6 Aug 2001 at an abattoir.
    As the cow had dystaxia, a brain sample was taken and sent to the National Institute of Animal Health (NIAH) and subjected to Prionics Check test with a negative result on 15 Aug 2001. A brain sample from this cow was also sent to the prefecture Livestock Hygiene Service Center and subjected to histopathological examination and found to have vacuoles on 24 Aug 2001. The same brain sample was sent to the NIAH on 6 Sep 2001 for histopathological examination with the same result, and subjected to immunohistochemical examination with a positive result on 10 Sep 2001. Control measures: immediately after bovine spongiform encephalopathy was suspected, the herd was been placed under quarantine by the prefecture veterinary inspector.

    58. Bovine Spongiform Encephalopathy (BSE-"Mad Cow Disease")
    The summary for this Japanese page contains characters that cannot be correctly displayed in this language/character set.
    http://ss.niah.affrc.go.jp/bse/bse-s.html
    ‹ŠC–ȏó”]Ç-Bovine Spongiform Encephalopathy ( BSE )‚̃y[ƒW‚͉º‹LURL‚Ɉڍs‚µ‚Ä‚¨‚è‚Ü‚·B http://niah.naro.affrc.go.jp/disease/bse/bse-s.html

    59. Bovine Spongiform Encephalopathy
    bovine spongiform encephalopathy (BSE), or mad cow disease. Bovine spongiformencephalopathy (BSE) and CreutzfeldtJakob disease (CJD).
    http://www.brunel.ac.uk/research/cshsd/bovine_spongiform_encephalopathy.htm
    Bovine spongiform encephalopathy (BSE), or mad cow disease
    By Stuart Neilson, PhD, director of medical information systems at the Centre for the Study of Health (CSHSD) , Brunel University (click on my name to send me mail, but please include a descriptive Subject: line in the message). The latest version of this document can be found at http://http2.brunel.ac.uk:8080/~hssrsdn/bse/article.htm Follow these links to return to the index , for a list of references to this article , a bibliography of BSE research and other TSE research. Note: Full abstracts of many of the papers cited here are available from the browsable CABI BSE database. A comma-delimited-list file is also available in compressed form. Abstracts are a good starting point, but reading the original article is well advised.
    • How did it arise?
      1.1 The mainstream hypothesis
    What is not doubted is that infection by scrapie did not cause the epidemic, which was caused by the recycling of cattle protein back to cattle. Although scrapie can be transmitted to cattle [Gibbs et al, 1991] it has proved far less infectious than BSE-infected cattle brain. The potential for human risk has also been present throughout the epidemic [Patterson and Dealler, 1995].
    • 1.2 The environmental hypotheses

    60. VEIN Links : Bovine Spongiform Encephalopathy BSE
    Recommended resources for veterinary and animalscience. BSE bovine spongiform encephalopathy.
    http://vein.library.usyd.edu.au/links/bse.html
    About VEIN Research databases Links Library catalogue ... Links Recommended resources for veterinary and animal science
    BSE: Bovine Spongiform Encephalopathy
    This page is maintained with the assistance of Dr Robert Dixon of the University of Sydney, Faculty of Veterinary Science and Dr Andrew Turner.
    About the disease
    Also known as "mad cow disease", this is one of a number of transmissible encephalopathies that affect a range of species. Its cause is considered to be due to a 'prion', a mutant protein that is able to infect cells and induce the natural non-mutant protein in these cells to change its conformation into the mutant protein. This mutant protein proliferates and accumulates, inducing cellular disfunction and death. There is a long incubation in the disease with an insidious onset of signs. Central nervous signs include behavioural changes where animals become apprehensive or more nervous when having to go through gates etc. Animals will also show abnormalities in gait and posture including hindlimb ataxia and hypermetria. Affected cattle may also be hyperaesthetic reacting to sound or touch. All of these signs may be present. Increasing debility and weight loss occurs and progression to death can take up to several months. The important feature of the mutant prion proteins of TSE diseases are that they are relatively indestructible compared to normal brain cell proteins by being resistant to formalin and most disinfectants and highly resistant to heat. Temperatures of 1340C in steam at 3 bar pressure for 20 min is required to destroy prion activity.

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