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         Congenital Nephroblastoma:     more detail

81. ICD-9-CM Disease Index: W
spot lesions, teeth 521.0. White's disease (congenital) (keratosis follicularis)757.39; Wilms' tumor or neoplasm (nephroblastoma) (M8960/3) 189.0; Wilson's
http://www.cpmc.columbia.edu/homepages/hripcsa/icd9/2indexw.html
ICD-9-CM Index to Diseases: W
  • Waardenburg's syndrome 756.89
    • meaning ptosis-epicanthus 270.2
  • Waardenburg-Klein syndrome (ptosis-epicanthus) 270.2
  • Wagner's disease (colloid milium) 709.3
  • Wagner (-Unverricht) syndrome (dermatomyositis) 710.3
  • Waiting list, person on V63.2
    • undergoing social agency investigation V63.8
  • Wakefulness disorder (see also Hypersomnia) 780.54
    • nonorganic origin 307.43
  • Waldenstrom's
    • disease (osteochondrosis, capital femoral) 732.1
    • hepatitis (lupoid hepatitis) 571.49
    • hypergammaglobulinemia 273.0
    • macroglobulinemia 273.3
    • purpura, hypergammaglobulinemic 273.0
    • syndrome (macroglobulinemia) 273.3
  • Waldenstrom-Kjellberg syndrome (sideropenic dysphagia) 280.8
  • Walking
    • difficulty 719.7
    • psychogenic 307.9
    • sleep 307.46
    • hysterical 300.13
  • Wall, abdominal=see condition
  • Wallenberg's syndrome (posterior inferior cerebellar artery) (see also Disease, cerebrovascular, acute) 436
  • Wallgren's
    • disease (obstruction of splenic vein with collateral circulation) 459.89
    • meningitis (see also Meningitis, aseptic) 047.9
  • Wandering
    • acetabulum 736.39

82. Nephroblastoma - Part B
TX. nephroblastoma (WILMS TUMOR). nephroblastoma Components and Patterns. neural.nephroblastoma Light microscopy and Ultrastructure.
http://sup.ultrakohl.com/uscap/abs-1998/nephr-B.htm
Back to Pediatric Renal Home Page
REVIEW OF PEDIATRIC RENAL NEOPLASMS
John Hicks
Texas Children's Hospital, Houston, TX
NEPHROBLASTOMA (WILMS TUMOR)
INDEX Nephroblastoma:
Components and Patterns
Three Primary Elements
Blastema
- diffuse pattern
- organoid pattern
serpentine
nodular
basaloid
Epithelial-Lined Tubules - tubular pattern - glomeruloid pattern - papillary pattern - pelvicalyceal pattern - cysts/glands - heterologous patterns mucinous squamous neural neuroendocrine Primitive Stroma Cell Types - undifferentiated - myxoid - fiboblastic - smooth muscle - skeletal muscle - cartilage - osteoid/bone - adipose tissue - neural Nephroblastoma: Light microscopy and Ultrastructure Figure 1A: Epithelial area with tubule formation (light microscopy) Figure 1B: Epithelial area with elongated cell attachment (electron microscopy) Nephroblastoma: Staging Stage I: Tumor confined to kidney and completely resected Stage II: Microscopic residual tumor Tumor penetration through renal capsule

83. Nephroblastoma - Part A
nephroblastoma (WILMS TUMOR). nephroblastoma (Wilms Tumor) Epidemiology. Incidence 29months 33 months. nephroblastoma (Wilms Tumor) Clinical Features.
http://sup.ultrakohl.com/uscap/abs-1998/nephr-A.htm
Back to Pediatric Renal Home Page
REVIEW OF PEDIATRIC RENAL NEOPLASMS
John Hicks
Texas Children's Hospital, Houston, TX
NEPHROBLASTOMA (WILMS TUMOR)
INDEX Nephroblastoma (Wilms Tumor): Epidemiology Incidence 5 to 6% of All Childhood Cancers n United States Cases per year in United States African-Americans Gender Ratio
(bilateral tumors) Mean Age for Unilateral Tumors
Male
Female Mean Age for Bilateral Tumors
Male
Female 90% Occur in Children
8.1 per million children
Highest Incidence
41 months 47 months 29 months 33 months Nephroblastoma (Wilms Tumor): Clinical Features Bilateral Tumors Abdominal Mass Abdominal Pain Acute Abdomen Hypertension Fever Hematuria Weight Loss Urinary Tract Infection Nausea/Vomiting Urogenital Anomalies (Renal Ectopia, Unilateral Agenesis, Horseshoe Kidney, Ureteral Duplication, Hypospadias, Cryptorchidism) Hemihypertrophy Aniridia Nephroblastoma (Wilms Tumor): Cytogenetics WT1 Tumor Suppressor Gene: A Constitutional Deletion Chromosome 11p13 WAGR Syndrome Nonhereditary Wilms Tumor (33%) 10 Exons Encoding for a 45-49 kd Protein Homology to Early Growth Response 1 (EGR1) Sequence Specific DNA Binding Regulate Transcription of Other Genes 30 to 40% of Wilms with Loss of Heterozygosity for region with WT1

84. Www.afip.org/vetpath/WSC/WSC94/94wsc28.txt
congenital diverticula contain all layers of the intestinal wall, while Rhabdomyocyticnephroblastoma, bilateral, kidney, swine Histologic examination of 4 æm
http://www.afip.org/vetpath/WSC/WSC94/94wsc28.txt

85. MUMS List Of Disorders - N - O
nephroblastoma (kidney cancer) (1); Nephrocalcinosis (3); Nephrogenic Diabetes NeuropathyCongenital Hypomyelination (5) *; Neuropathy Hereditary Type II (2
http://www.netnet.net/mums/mum_n-o.htm
Return to MUMS Home Page
MUMS:
List of Disorders
N - O
Number in parentheses indicates number of matches.
indicates there is a support group which covers that diagnosis.
  • N-Acetylglucosamine-1-phosphotransferase Deficiency (6)
  • NADH-Co Enzyme Respiratory Chain Complex 1Q Oxidoneductase (2)
  • Nager Syndrome (4) *
  • Nail-Patella Syndrome (3)**
  • Nails, Abnormal (don't grow,creased,thick etc.) (39)
  • Narcolepsy (5) *
  • Nasal Cannula (2)
  • Nasal Encephalocele (1)
  • Near-Drowning (43) * http://www.hugsfoundation.org/
  • Near-Electrocution (1)
  • Near-Hanging (5)
  • Near SIDS (4)
  • Near-Suffocation (1)
  • Necrotizing Enterocolitis (22)
  • Nemaline Myopathy (16) *
  • Neonatal Tooth (1)
  • Nephroblastoma (Benign Tumors on Kidneys) (3)
  • Nephroblastoma (kidney cancer) (1)
  • Nephrocalcinosis (3)
  • Nephrogenic Diabetes Insipidus (16) *
  • Nephronophthisis, Juvenile (1)
  • Nephropathy, C1Q (1)
  • Nephropathy, IGA (1)*
  • Nephrotic Kidney Syndrome (13) *
  • Nephrotic Kidney Syndrome (Minimal Change Disease) (4) *
  • Nephrotic Kidney Syndrome (steriod resistant) (1)
  • Neroentric Cyst (1)
  • Nerve Damage from Dog Bite (1)
  • Nesidioblastosis (8)
  • Netherton Syndrome (3)*
  • Neuroaxonal Dystrophy, Infantile (Seitelberger Disease) (5)*

86. Nephroblastom Review
Since that time the association of nephroblastoma and other different congenitalanomalies, notably aniridia hemihypertrophy and malformations of genitalia
http://www.med-rz.uni-sb.de/med_fak/kinderklinik/Review/body_review.htm
Wilms´tumour - the state of the art
Prof. Dr. N. Graf  
Wilms´tumour or nephroblastoma was first described as a renal neoplasm by Rance in 1814 (1). In 1899 Max Wilms, a surgeon, wrote a detailed monograph "Die Mischgeschwülste der Niere" (2), that gave later this tumour his name. It is a tumour, that was always incurable in former days, but that is today one of the best curable malignancies. The improvement in treatment is based mainly on the progress of surgery, radiotherapy and in the development of effective chemo- therapeutics. Interdisciplinary teamwork and prospective randomised multicenter studies are clues for the achieved increase in prognosis. Epidemiology, Incidence Nephroblastoma, being 6 % of all malignancies in children, is the most common childhood renal tumour. The annual incidence rate of Wilms´tumour is 8 / 1.000.000 children under the age of 15 years, meaning that about 1 out of 100.000 children will suffer of this neoplasm. In Germany more than 100 new cases occur every year (3). The highest incidence rates are reported among United States blacks, in Finland and regions of France, the lowest rates are reported from Asia (4). World-wide the sex ratio is 1:1. The distribution of age at diagnosis peaks at 2 to 3 years in unilateral cases and is lower in children with a bilateral tumour. Bilateralisation will occur in 5 % of nephroblastoma (5). Aetiology and genetics In 1964 Miller et al. (6) reported for the first time of an association of Wilms´tumour and aniridia. Since that time the association of nephroblastoma and other different congenital anomalies, notably aniridia hemihypertrophy and malformations of genitalia (cryptorchidism, hypospadias, pseudohermaphroditism and gonadal dysgenesis) is well known. Aniridia and hemihypertrophy are extremely rare in the general population, and children with either of these conditions should be screened carefully for Wilms´tumour. The disease occurs in conjunction with neurofibromatosis, WAGR (Wilms´tumour, aniridia malformations of genitalia, retardation) Beckwith-Wiedemann (BWS), Drash (pseudohermaphroditism, glomerulopathy, and Wilms´tumour) and Perlman familial nephroblastomatosis (bilateral renal hamartomas, macrosomia, islet cell hypertrophy, unusual facial) malformation syndromes (7).

87. Archives Of The AFIP -- RadioGraphics 1995; 15: 653-669
BM, Mancer K. Magnetic resonance imaging of cystic, partially differentiated nephroblastoma. Congenitalmesoblastic nephroma of infancy report of a case with
http://www.rsna.org/REG/publications/rg/afip/privateM/1995/0015/0003/0653/10.htm
RadioGraphics
Multilocular Cystic Renal Tumor in Children
Radiologic-Pathologic Correlation
Abstract
Introduction and Historical Background

Clinical Features
Pathologic Features ...
Source Information

References
References

88. Large Muscles
Adrenal; nephroblastoma; Hepatoblastoma; Rhabdomyosarcoma; Wilms tumor; Congenitalgastric teratoma; Hemangiomas. GU Renal medullary dysplasia; Overgrowth of
http://www.neuro.wustl.edu/neuromuscular/mother/mlarge.html

Front
Search Index Links ... Patient Info
LARGE OR PROMINENT MUSCLES
Drugs
Endocrinopathy

Focal enlargement

Infections
...
Storage disorders

Amyloidosis:
Enlarged tongue
Overusage
Partial Denervation Endocrinopathy Muscular Dystrophies

89. Wilms Tumor
Alternate Names nephroblastoma; Kidney tumor. It is associated with certain congenitaldefects including urinary tract abnormalities, absence of the iris
http://www.rwjhamilton.org/Atoz/encyclopedia/article/001575.asp
For a complete list of hospital classes and events, click here to connect to HealthConnection Online
Medical Encyclopedia Encyclopedia Disease W -> Wilms tumor Wilms tumor Alternate Names: Nephroblastoma; Kidney tumor Causes and Risks: Wilms tumor is one of the most common intraabdominal tumors in children and the most common type of kidney tumor. The exact cause of tumor formation is unknown, but it probably develops in fetal tissue. It is associated with certain congenital defects including urinary tract abnormalities, absence of the iris (aniridia) and hemihypertrophy (enlargement of one side of the body), and shows an increased incidence among siblings and twins, which suggests a possible genetic cause. The tumor may become quite large, but usually remains encapsulated (self-enclosed). It may spread to other body tissues.
The frequency of disease occurrence is estimated to be about 1 out of 200,000 to 250,000 children. The peak incidence is at 3 years old. Rarely, the tumor may be present in adults. Symptoms:

90. Diagnostic Pathology
Translate this page causes of nephrotic syndrome Post infectious, toxic, SLE, HUS, other congenitaldiseases (Nail patella syndrome, brain malformations, nephroblastoma).
http://www.pathology.lsumc.edu/Pathist/RENAL/GLOMERULOPATHIES/24MSGD/MSGDb

91. DEPARTMENT OF PAEDIATRIC SURGERY
Haemangioma; Lymphangioma – the Hamartomatous tumours of childhood. Congenitalanomalies related to the branchial arches. nephroblastoma (Wilms’ tumour).
http://web.uct.ac.za/depts/ich/teaching/undergrad/5th_year/surg5_01.htm
DEPARTMENT OF PAEDIATRIC SURGERY INTRODUCTION Magnitude and scope of surgery in childhood
Three major causes of death in childhood are surgical problems:
  • Accidents
  • Congenital malformations
  • Malignancy Great process in the surgical care of neonates, infants and children has been made. Today Paediatric Surgery stands fully recognised as a speciality in its own right. Students are expected to study the following:
    • Inguinal hernia and "hydrocoele" in infants and children.
    • The imperfectly descended testis.
    • Congenital anomalies related to the branchial arches.
    • Neuroblastoma.
    • Intussusception.
    • Meningomyelocoele and associated neural tube defects.
    • Burns.
    • Osteomyelitis.
    • Neonatal obstruction of the GIT including oesophageal atresia.
    • Acute appendicitis in children.
    • Exomphalos, true umbilical hernia and para-umbilical hernia.
    • Causes and management of blood in the stool of children.
    • Polypi in children.
    • Diaphragmatic herniae.
    • Cervical lymph node enlargement.
    • The injured child including non-accidental injury.
    Salient features of surgical disease In trying to grasp the important features of a large number of unfamiliar surgical conditions, it is easy to get side-tracked into a morass of minutiae. The student will make effective use of his limited time and energy by forcing him to concentrate upon the following aspects of each condition described above.
  • 92. Untitled
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    http://www.acor.org/cnet/705455.export
    AU - Granzen B; Efferth T; Keller U; Beniers AJ; Mertens R; Jakse G; Fuzesi L TI - Differential expression of the drug resistance markers DNA topoisomerase II alpha and glutathione S-transferase-pi in the histological compartments of Wilms' tumors. SO - Anticancer Res 2001 Jan-Feb;21(1B):771-6 AD - Department of Children and Adolescents, University Hospital Aachen, Germany. AB - More than 80% of the patients presenting with Wilms' tumor can be cured today. Some patients, however, fail to respond to chemotherapy. The objective of this study was to analyze the immunohistochemical distribution of two markers of cytostatic drug resistance, e.g. DNA topoisomerase II alpha (Topo II alpha) and glutathione S-transferase-pi (GST-pi) in 23 Wilms' tumor patients who had undergone an operation between 1984 and
    1997. Eight patients had stage I disease, seven stage II, three stage III, four stage IV, and one stage V disease.

    2 UI - 21074660 AU - Heij HA TI - The management of nephroblastoma in a rural hospital. SO - Trop Doct 2001 Jan;31(1):39-40 AD - St Francis' Hospital, Katete, Zambia. ha.heij@azvu.nl
    3 UI - 21125012 AU - McHugh K; Pritchard J TI - Problems in the imaging of three common paediatric solid tumours. SO - Eur J Radiol 2001 Feb;37(2):72-8 AD - Great Ormond Street Hospital for Children, London WC1N 3JH, UK. AB - Modern radiologic techniques have led to a more accurate diagnosis and staging in many paediatric malignancies. The optimal imaging of some tumours is not, however, well defined and needs to be constantly re-assessed. Similarly with evolving clinical treatment protocols, recommended imaging strategies should be continually re-evaluated. The significance of some findings on radiologic examinations in paediatric oncology patients is disputed. A number of issues relating to the imaging of Wilms', neuroblastoma and rhabdomyosarcoma in childhood are discussed.

    93. Web Wombat World Directory
    Top Health Conditions and Diseases Cancer Genitourinary Kidney Wilm's_Tumor__Congenital_Nephroblastoma
    http://www.webwombat.com.au/wwdir/WW386759.HTM
    Entertainment Finance Games Lifestyle ... Auctions You are here: Home / World Directory Daily Resources Holiday Ideas Daily Horoscopes Weather by the hour What's on TV ... Grumpy's Humour Premium Links Find a Date Jobs! Jobs! Jobs! Mobile Phone Ringtones Home Loans Home Loans ... Hot Links Web Wombat Search Advanced Search Submit a Site Enter search term: World Directory Top Health Conditions and Diseases Cancer ... Kidney : Wilm's_Tumor
    Categories Web Sites
    • Wilm's Tumor - Discussion about this disorder including warning signs, treatment and statistics. Some links provided for further searching.
    • Wilm's Tumor Homepages - Links lead to the home pages of families with children who have Wilm's tumor.
    • OnTumor.com: Wilm's Tumor - Offers information such as staging and treatment overviews. From the National Cancer Institute.
    • Childhood Cancer Center: Wilm's Tumor - This information center has been created especially for parents and others caring for a child with a solid tumor cancer. An in depth look at this disease.
    Help build the largest human-edited directory on the web.

    94. Directory Vaionline: Siti_Mondiali/Health/Conditions_and_Diseases/Cancer/Genitou
    directory.vaionline.it vi permette di accedere al directory di siti italiani. E' organizzato per aree geografiche e aree temeatiche. Fa parte del portale Vaionline che ti offre molti altri servizi.
    http://directory.vaionline.it/Siti_Mondiali/Health/Conditions_and_Diseases/Cance
    in questa categoria in tutti siti mondiali
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    Health Cancer Genitourinary : Kidney
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    95. Directory :: Look.com
    Look.com The Search Engine of Search Engines, Enterprise Search Look Search,
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