1. Diabetes Insipidus Foundation, Inc. Provides information on the different forms of diabetes insipidus. Includes email support group, Category Health Conditions and Diseases diabetes insipidus......Welcome to the Water World of diabetes insipidus A DiFferent Diabetes. . Whatis diabetes insipidus? Contact The diabetes insipidus Foundation, Inc. http://diabetesinsipidus.maxinter.net/

Welcome to the Water World of Diabetes Insipidus: "A DiFferent Diabetes." What is Diabetes Insipidus? diabainein: Greek, "to pass through" insipidus: Latin, "having no flavor" Also known as "water diabetes," it is often mistaken for diabetes mellitus/sugar diabetes. It is a rare disease, not widely diagnosed, in which the kidneys produce abnormally large volumes of dilute urine. DiF's website includes information on all four forms of Diabetes Insipidus, as well as articles, brochures, stories, FAQ's, networking, Research Opportunities, a Professional Section including the Water Deprivation Protocol , and a section for Pets. Please go to the Table of Contents for a detailed listing of the site. There are four (4) fundamentally different types of Diabetes Insipidus (DI). Each has a different cause and must be treated in a different way. These four forms are: Neurogenic , also known as central hypothalamic, pituitary or neurohypophyseal is caused by a deficiency of the antidiuretic hormone, vasopressin.

2. Nephrogenic Diabetes Insipidus Foundation NDI Information & Resources The NDI Foundation was formed to support education, research, treatment, and cure for nephrogenic diabetes insipidus. http://www.ndif.org/

The Nephrogenic Diabetes Insipidus Foundation is dedicated to informing and helping the NDI community. About the NDI Foundation Journal Articles Researcher Directory Global Conferences Questionnaires Foundation News Researcher Profiles Terminology Medical Alert Cards Frequently Asked Questions Nutrition Guidelines How Can I Help? TABLE of CONTENTS INFORMATION REQUEST Nephrogenic Diabetes Insipidus Foundation Main Street P.O. Box 1390 Eastsound, WA 98245 (voice) 888-376-6343 (fax) 888-376-6356 e-mail: info@ndif.org Last updated March 28, 2003 You are visitor: 272750 Site developed by: orcas net, inc NDI foundation, nephrogenic, diabetes, insipidus, kidney disorder, urination, thirst, nephrogenic diabetes insipidus, NDI foundation, nephrogenic, diabetes, insipidus, kidney disorder, urination, thirst, nephrogenic diabetes insipidus

3. MEDLINEplus Medical Encyclopedia: Diabetes Insipidus DI caused by a lack of ADH is called central diabetes insipidus. When DI is caused by failure of the kidneys to respond http://www.nlm.nih.gov/medlineplus/ency/article/000377.htm

Skip navigation Medical Encyclopedia Other encyclopedia topics: A-Ag Ah-Ap Aq-Az B-Bk ... Z Diabetes insipidus Contents of this page: Illustrations Definition Causes, incidence, and risk factors Symptoms ... Calling your health care provider Illustrations Endocrine glands Definition Return to top A condition caused by the inability of the kidneys to conserve water that leads to frequent urination and pronounced thirst. Causes, incidence, and risk factors Return to top Diabetes insipidus (DI) is an uncommon condition that occurs when the kidneys are unable to conserve water as they perform their function of filtering blood. The amount of water conserved is controlled by antidiuretic hormone (ADH, also called vasopressin). It is a hormone produced in a region of the brain called the hypothalamus. ADH is then stored and released from the pituitary gland, a small gland at the base of the brain. DI caused by a lack of ADH is called central diabetes insipidus. When DI is caused by failure of the kidneys to respond to ADH, the condition is called nephrogenic diabetes insipidus. The major symptoms of diabetes insipidus are excessive urination and extreme thirst. The sensation of thirst stimulates patients to drink large amounts of water to compensate for water lost in the urine. Central diabetes insipidus is caused by damage to the hypothalamus or pituitary gland as a result of surgery, infection

4. Diabetes Insipidus What is diabetes insipidus? diabetes insipidus is a rare disorder of water metabolism. This means that the balance between how much water or fluid you drink is not balanced with the fluid you urinate. http://www.geocities.com/Tokyo/5830/diabetes_insipidus.htm

Diabetes Insipidus Contents What is Diabetes Insipidus? Types of Diabetes Insipidus and their symptoms Can Diabetes Insipidus be Prevented? How is Diabetes Insipidus Diagnosed? ... Coping with the Everyday Effects of Diabetes Insipidus What is Diabetes Insipidus? Types of Diabetes Insipidus? There are two types of diabetes insipidus. While the symptoms of these two disorders are similar, the causes are different. Central diabetes insipidus If you have been diagnosed with central diabetes insipidus, there are some things you should know about how the disorder is caused and what you and your doctor can do about it. What causes it? In central diabetes insipidus, the antidiuretic hormone vasopressin is either missing or present at a low level. This low level or lack of vasopressin is due to a malfunction in the part of your brain, the posterior pituitary gland, which releases the hormone into your blood-stream. Tumour of the pituitary gland. Head injury, with damage to pituitary gland.

5. Pets With Diabetes: Diabetes Insipidus Pets With Diabetes diabetes insipidus A disorder of water balance What is diabetes insipidus? diabetes insipidus (DI) is a disorder of water balance. http://www.petdiabetes.org/diabetes_insipidus.htm

Diabetes Insipidus Diabetes Insipidus Types Signs ... References What is Diabetes Insipidus? Diabetes insipidus (DI) is a disorder of water balance. The animal is unable to concentrate urine, so the urine volume is very high and the urine is dilute. "Insipid" means tasteless referring to the dilute urine. This disease is rare in both dogs and cats. The condition is usually permanent, and the prognosis is good. Without treatment, dehydration leads to stupor, coma, and death. This is a completely different disease from Diabetes Mellitus (DM), a disorder of sugar metabolism involving the hormone insulin. We include the information here because people are often looking for resources and we had some owners of pets with DM who also have experience with DI. Types of diabetes insipidus Central Diabetes Insipidus - caused when the pituitary gland does not secrete enough antidiuretic hormone (ADH) [also called vasopressin]. This type of DI may be the caused by a congenital defect, trauma, a tumor on the pituitary gland, or unknown causes. Nephrogenic Diabetes Insipidus - caused when the kidneys do not respond to the ADH that is produced by the pituitary gland. This type of DI may be caused by a congenital defect, drugs, or caused by other metabolic disorders

6. Diabetes Insipidus Patient information from the American Academy of Family Physicians.Category Health Conditions and Diseases diabetes insipidus......Return to Index, Information from Your Family Doctor. diabetes insipidus.What is diabetes insipidus? What causes diabetes insipidus? http://familydoctor.org/handouts/048.html

This handout is also available in Spanish. Information from Your Family Doctor Diabetes Insipidus What is diabetes insipidus? Despite the similar names, diabetes insipidus is not related to diabetes mellitus (which is sometimes called sugar diabetes). Some people with diabetes insipidus have kidneys that don't concentrate urine very well (meaning their urine is more diluted). They have to urinate very often. They might wake up 2 or 3 times in the night to urinate. People with diabetes insipidus are thirsty all the time. They often want to drink liquids every hour. What causes diabetes insipidus? Two things cause diabetes insipidus. In some people, a part of the brain (called the hypothalamus) doesn't make enough antidiuretic hormone (called ADH), which your body needs to work right. In other people, the kidneys don't work with this hormone the way they should. Most people with diabetes insipidus get it after an injury to the head or after brain surgery. Some people with diabetes insipidus have a brain tumor. Sometimes it runs in families. Some medicines, like lithium, can also cause it. About 25% of the time, doctors can't find any reason for it. How do you test for diabetes insipidus?

7. DIARD Home Page (Page 1) The diabetes insipidus and Related Disorders network is for persons who have, or care for someone Category Health Conditions and Diseases diabetes insipidus...... THE diabetes insipidus AND RELATED DISORDERS network is for persons who have,or care for someone with ,any form of diabetes insipidus disorder. http://hometown.aol.com/ruudh/dipage1.htm

htmlAdWH('7008213', '120', '30'); htmlAdWH('7004798', '234', '60'); Main Create Edit Help DIARD HOME PAGE THE DIABETES INSIPIDUS AND RELATED DISORDERS network is for persons who have, or care for someone with ,any form of Diabetes Insipidus disorder. The main purpose of this network is to offer support for those surrounded by lack of information on these rare disorders. DEFINITION DI is defined as a condition in which urine is not concentrated (urine is dilute or water-like). Concentration of urine in normally functioning individuals is the consequence of secretion of antidiuretic hormone (ADH) by the posterior pituitary gland in the brain, and a corresponding reaction by receptors on the kidneys. ADH tells the kidneys how much water to keep in the body and how much water to eliminate as urine. There are at least two separate types of DI. In Central Diabetes Insipidus (CDI, also known as Vasopressin-sensitive DI), the pituitary gland fails to produce ADH. In Nephrogenic Diabetes Insipidus (NDI, also known as "antidiuretic hormone" or Vasopressin-resistant DI), the pituitary gland may be secreting ADH, but the kidneys fail to react to it. The treatments for either of these root causes are entirely different. The basic symptoms for both disorders are however the same and generally include: Persistent thirst, drinking large amounts of fluids, and urinating frequently

8. D - Diabetes Insipidus diabetes insipidus. diabetes insipidus is a disorder in which the kidney is insensitive to a hormone, called antidiuretic http://www.vetinfo.com/dencyclopedia/dedibetinsp.html

Vetinfo Canine Encyclopedia Feline Encyclopedia VetInfo Digest ... Your Turn Encyclopedia of Canine Veterinary Medical Information Diabetes Insipidus Diabetes insipidus is a disorder in which the kidney is insensitive to a hormone, called anti-diuretic hormone (ADH) or in which there is not sufficient quantity of this hormone available. The result is excessive drinking and urination, or polydipsia and polyuria. This is one cause of changes in urinary habits that leads to problems with urination inside the house in dogs in which "housebreaking" seemed to be satisfactory prior to the disease onset. ADH is secreted by the body when it has a need to conserve water. It makes the kidneys work harder to conserve water, which makes the urine more concentrated. When the dog can not respond to this hormone or doesn't make enough of it, the dog can not concentrate its urine. This can lead to serious problems, including death, if the dog does not have access to large quantities of water. On the other hand, it may not cause any significant problem if there is always plenty of water available. This problem can occur for a number of reasons and for no reason at all. Examples of predisposing causes are kidney failure, hyperadrenocorticism, liver disease, pyometra and others. These things affect the kidney's ability to respond. Head trauma or brain cancer can affect the body's ability to produce ADH. This condition is treated using desmopressin acetate (DDAVP), which is a replacement for the anti-diuretic hormone. It can be administered intra-nasally or on the conjunctiva (the inside lining of the eyes). It is pretty effective. Unfortunately, it is also somewhat expensive. Some dogs benefit from therapy with other medications, including chlorpropamide and chlorothiazide diuretics.

9. Family Village -- Diabetes Insipidus Informative collection of links including who to contact, chat room and support details, and organisations and websites that deal with DI http://www.familyvillage.wisc.edu/lib_di.htm

Diabetes Insipidus See also Diabetes Who to Contact Where to Go to Chat with Others Learn More About It ... Search AltaVista for "Diabetes Insipidus" Who to Contact Diabetes Insipidus and Related Disorders Network (DIARD) 1622 185 Street Creston, Iowa 50801-8172 Website: http://members.aol.com/ruudh/dipage1.htm This organization's mission is to maintain a support network for patients and their families dealing with diabetes insipidus (DI) of any form, provide emotional and informational support to those families, educate and promote education related to diabetes insipidus, and promote scientific research in diabetes insipidus (seeking to develop better means of treatment, and ultimately, seeking to develop a scientific prevention and cure of DI). Diabetes Insipidus Foundation, Inc. (DIF) 4533 Ridge Drive Baltimore, Maryland 21229 (410) 247-3953, mailbox #1 Fax: (410) 247-5584 E-mail: diabetesinsipidus@amdyne.net Website: http://diabetesinsipidus.amdyne.net/ This foundation seeks to encompass all four forms of Diabetes Insipidus (DI). These four forms are: (1) Neurogenic, also known as central, hypothalamic, pituitary or neurohypophyseal is caused by deficiency of the antidiuretic hormone, vasopressin; (2) Nephrogenic, also known as vasopressin-resistant is caused by insensitivity of the kidneys to the effect of the antidiuretic hormone, vasopressin; (3) Gestagenic, also known as gestational is also caused by a deficiency of the antidiuretic hormone, vasopressin, that occurs only during pregnancy; and (4) Dipsogenic, a form of primary polydipsia is caused by abnormal thirst and the excessive intake of water or other liquids.

10. Endocrinology - Diabetes Insipidus - Methodist Health Care System, Houston, Texa Information on DI incluing causes, symptoms, diagnosis, and treatments. http://www.methodisthealth.com/endocrin/diabins.htm

Endocrinology Home Page Endocrinología (en español) Clinical Services The Methodist Hospital Methodist Diagnostic Hospital Methodist Sugar Land Hospital Methodist Willowbrook Hospital ... Appointment Diabetes Insipidus Fact: Though produced by the hypothalamus, the portion of the brain that stimulates the pituitary gland, the antidiuretic hormone is actually stored and released into the bloodstream by the pituitary gland. What is diabetes insipidus? Causes of diabetes insipidus: Diabetes insipidus can be caused by several conditions, including the following: malfunctioning hypothalamus malfunctioning pituitary gland damage to hypothalamus or pituitary gland during surgery brain injury tumor tuberculosis blockage in the arteries leading to the brain encephalitis meningitis sarcoidosis (a rare inflammation of the lymph nodes and other tissues throughout the body) What are the symptoms of diabetes insipidus? The following are the most common symptoms of diabetes insipidus. However, each individual may experience symptoms differently. Symptoms may include: excessive thirst excessive urine production dehydration The symptoms of diabetes insipidus may resemble other conditions or medical problems. Always consult your physician for a diagnosis.

11. Online Library Considerably well written informative article with a lot of detail on what DI is, how it affects you, symptoms, prevention, diagnosis, treatments with many reference links for the newly diagnosed to the medical professional. http://www.histio.org/us/lib/diabetes.html

Current Time Sunday, 30-Mar-2003 20:34:51 EST Online Library Histiocytosis Association of America Information about the Histiocytosis Association of America Histiocytosis Association of America Board of Trustees Histiocytosis Association of America Contact Information Scheduled Events Information Request Form Patient Survey Getting Involved with the Histiocytosis Association Website Lounges Live Chat Online Library Histiocyte Society The Histiocytosis Association of America is not responsible for the content of entries identified with the external page icon. General Information Common Symptoms of Histiocytosis Facts about Langerhans Cell Histiocytosis Los Hechos Sobre Histiocitosis de Langerhans C©lula Langerhans Cell Histiocytosis in Adults ... The Facts About Diabetes Insipidus General overview of diabetes insipidus, including symptoms and treatment. Facts about DDAVP (desmopressin acetate) Detailed information provided by MEDLINEplus. LCH Skin Lesions Photographs of various skin manifestations of LCH. The Facts About HLH (Hemophagocytic Lymphohistiocytosis) and FHL (Familial Hemophagocytic Lymphohistiocytosis) A brief overview of hemophagocytic lymphohistiocytosis and familial hemophagocytic lymphohistiocytosis.

12. GeneReviews: Nephrogenic Diabetes Insipidus Information including detailed statistics, summary of the illness, clinical descriptions, diagnosis, Category Health Conditions and Diseases diabetes insipidus......Your browser does not support HTML frames so you must view Nephrogenic DiabetesInsipidus in a slightly less readable form. Please follow this link to do so. http://www.geneclinics.org/profiles/ndi/

Your browser does not support HTML frames so you must view Nephrogenic Diabetes Insipidus in a slightly less readable form. Please follow this link to do so.

13. Disorder-Specific Survival Kit Nephrogenic Diabetes Insipidus Includes information about the cause, diagnosis and management of NDI and other types of diabetes insipidus. http://depts.washington.edu/transmet/The process/ndi.htm

Disorder-Specific Survival Kit: Nephrogenic Diabetes Insipidus Information about NDI The cause of NDI Other types of diabetes insipidus Management of NDI ... Selected Medical and Scientific References Information about NDI Nephrogenic diabetes insipidus (NDI) is a disorder characterized by an inability of the kidneys to remove water from the urine. The main symptoms of NDI are excessive thirst (polydipsia) and excretion of large amounts of watery urine (polyuria). Individuals with NDI must drink large amounts of water to compensate for the loss of water in the urine. As a result, a person with NDI must urinate more frequently than usual. The Cause of NDI NDI is caused by an inability of a water-saving hormone to work properly in the kidneys. A hormone is a natural chemical made by the body that works in a different part of the body than where it was made. The hormone involved in NDI is called antidiuretic hormone (ADH), also known as vasopressin. Making ADH is one of the mechanisms which help keep water balance normal in the body. Usually, ADH allows the kidneys to save water that would otherwise be lost in the urine. The kidneys are the organs that make urine and help control the balance of water, salt, and other natural substances in the body. ADH is made by the pituitary gland, a small organ at the base of the brain that makes many different hormones. ADH is released into the blood stream where it travels to the kidneys. The amount of ADH made by the pituitary gland depends on the body's water needs. The more water the body needs, the greater the amount of ADH made by the pituitary gland. Only when there is plenty of water does the pituitary gland make less ADH.

14. Thomas Jefferson University Hospital - Diabetes Insipidus Basic fact sheet on diabetes insipidus. Includes causes, treatments and diagnosis. http://www.jeffersonhospital.org/show.asp?durki=4866

15. DIABETES INSIPIDUS Printable and easy to understand fact sheet that covers the basics of diabetes insipidus http://www.rxmed.com/b.main/b1.illness/b1.1.illnesses/DIABETES INSIPIDUS.htm

General Illness Information Common Name: Diabetes Insipidus Medical Term: Description: A rare disorder, resulting in excessive thirst and excessive passage of very dilute urine, due to a hormone deficiency in the pituitary gland, which is situated at the base of the brain. Diabetes Insipidus results from a decreased production of antidiuretic hormone ( vasopressin) , the hormone that normally prevents the kidney from producing too much urine. Antidiuretic hormone is produced in the hypothalamus, then stored and released in the blood stream by the posterior pituitary. Diabetes insipidus may also occur with normal levels of antidiuretic hormone, when the kidneys do not respond normally to the hormone. This condition is called nephrogenic diabetes insipidus. Causes: Diabetes Insipidus may have several causes which are as follows: Tumor of the pituitary gland;

16. Diseases And Conditions -- Discovery Health -- Diabetes Insipidus diabetes insipidus (DI) is a condition in which a person is thirsty all the time, drinks large amounts of fluids, and produces large amounts of urine. It is not the same condition as the more commonly known diabetes mellitus. http://health.discovery.com/diseasesandcond/encyclopedia/593.html

diabetes insipidus By Eileen McLaughlin, RN, BSN Images (click to view larger image) Diabetes insipidus (DI) is a condition in which a person is thirsty all the time, drinks large amounts of fluids, and produces large amounts of urine. It is not the same condition as the more commonly known diabetes mellitus What is going on in the body? When a person has diabetes insipidus, it is almost as if everything he or she drinks passes right through the kidneys. The 4 forms of DI are: central or neurogenic, in which a defect in the brain causes a shortage of vasopressin, or antidiuretic hormone (ADH). This hormone normally tells the kidneys how much urine to release. nephrogenic, in which a kidney defect causes an abnormal response to vasopressin pregnancy-induced, in which there is a low level of vasopressin during the pregnancy primary polydipsia, which is an abnormally high level of thirst and fluid intake What are the signs and symptoms of the disease? Symptoms of diabetes insipidus include: excessive urination: anywhere from 4 to 16 liters a day or more excess thirst inability to quench thirst dry skin and mucous membranes constipation muscle weakness dehydration , causing dizziness and general weakness the need to urinate during the night fatigue from getting up to urinate during the night What are the causes and risks of the disease?

17. Diabetes Insipidus Foundation, Inc. - Related Links diabetes insipidus Message Board in the UK, Diabetes UK has been set up forpeople in the UK who suffer from diabetes insipidus or their families. http://diabetesinsipidus.maxinter.net/dilinks.htm

Diabetes Insipidus Message Board in the UK Diabetes UK has been set up for people in the UK who suffer from Diabetes insipidus or their families. Diabetes Insipidus Message Board To provide information and support to professionals and lay people concerning all four forms of Diabetes Insipidus: neurogenic (central/pituitary);nephrogenic (vassopressin-resistant); dispogenic; and gestagenic/gestational DI.To promote discussion between the lay and professional communities. Diabetes Insipidus Message Board This group is open to anyone interested in making friends, sharing information and support with others affected by Diabetes Insipidus. DInsipidus Message Board This is an email list for patient and/or family members of patients diagnosed with Diabetes Insipidus (water diabetes). Whether nephrogenic, central or partial. Whether checking electrolytes, taking DDAVP or growth removal. Whether hereditary, brain trauma or pituitary tumor. All DI related email are welcome. This is not a list for Diabetes Mellitus (sugar diabetes). Drugs and Medications Drugs and Medication is a site dedicated to helping you find the information you need on today's drugs and medications.

18. About Lithium NDI Specific information and case examples about this potential adverse side effect. http://diabetesinsipidus.maxinter.net/about.htm

About Lithium NDI by Dr. David Marples, Department of Physiology, University of Leeds, England L ithium is often given to patients with manic-depressive disorder (also sometimes called bipolar depression). It is usually very effective in such conditions, but can be toxic if the dose is not carefully monitored and controlled. Lithium can have a number of side effects, of which the most prominent are increased drinking (polydipsia) and increased urine production (polyuria). These occur because lithium interferes with the way the kidney responds to the hormone ADH, which normally controls our urine production.This makes it an acquired form of nephrogenic (kidney-related) diabetes insipidus (NDI). U p to half of patients on lithium notice that they drink and urinate more. In around 1/5 of patients, this increase is enough to be quite troublesome, and occasionally it is very severe: in extreme cases it can be as bad as in inherited forms of NDI. T he situation is complicated by the fact that many psychiatric patients drink more than they need anyway - so-called psychogenic polydipsia - which of course also increases urine production. Therefore it is not always easy to know if the changes are due to the lithium treatment or not. T he effect is dose related, but the dose really has to be determined by what is needed to manage the manic depression for which the drug is given. (The blood levels of lithium are closely monitored because it is easy to get into the toxic range, which can be fatal, because of effects on the brain. This is more important than NDI).

19. NDI Terminology - Nephrogenic Diabetes Insipidus nephrogenic diabetes insipidus. DEFINITION See under diabetes insipidus.The definitions used in this glossary of terminology http://www.ndif.org/Terms/nephrogenic_diabetes_insipidus.html

nephrogenic diabetes insipidus DEFINITION: See under diabetes insipidus The definitions used in this glossary of terminology either have been provided by the authors of the articles, or have been extracted wholly or in part, or paraphrased from the following sources: The American Medical Association Encyclopedia of Medicine , Charles B. Clayman, MD, Medical Editor, Random House, New York, 1989; Dorland's Illustrated Medical Dictionary , 28th Edition, W. B. Saunders Company, Philadelphia, 1994; The Random House Dictionary of the English Language , Unabridged Edition, 1966; Webster's Ninth New Collegiate Dictionary TERMINOLOGY WHERE THIS WORD IS USED TABLE of CONTENTS INFO. REQUEST ENTRANCE

20. British Society For Paediatric Endocrinology And Diabetes (BSPED) Information leaflets about various endocrine (gland) disorders in children adrenal hypoplasia, hypothyroidism, Marfan's, diabetes insipidus, Turners, Klinefelters, obesity, precocious puberty and others. http://bspe.shef.ac.uk/

The website for the British Society For Paediatric Endocrinology and Diabetes has moved. BSPED now has its own domain name. New URL : http://www.bsped.org.uk/ If you have Javascript enabled, you will be transferred automatically. Please update your appropriate bookmarks.

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