41. Diptheria Tetanus Toxoids And Acellular Pertussis (DTaP), Infanrix Products Manufacturers Health Professionals Reading Room Meetings Workshops Research About Us. Product Approval Information Licensing Action. http://www.fda.gov/cber/products/dtapskb012997.htm

Blood Therapeutics Vaccines Allergenics ... About Us Product Approval Information - Licensing Action Proper name: Diphtheria and Tetanus Toxoids and Acellular Pertussis Vaccine Tradename: Infanrix Manufacturer: SmithKline Beecham Biologicals 1330 Rixensart, Belgium, License #1090 Indication for Use: Primary and booster immunization of infants and children except as a fifth dose in children who have previously received four doses of DTaP Approval Date: Type of submission: Biologics license application Approval Letter (PDF) (Text) Last Updated: 3/5/2001

42. Diptheria Home Conditions / Ailments diptheria DESCRIPTION This condition results fromthe bacillus Corynebacterium diphtheriae, which multiplies on the throat or http://www.herbalremedies.com/diptheria.html

Cosmetics Lotions Herbs Vitamins ... Conditions / Ailments > Diptheria > DESCRIPTION This condition results from the bacillus Corynebacterium diphtheriae, which multiplies on the throat or skin during infection. It causes a sore throat and fever, and it can be fatal. Children in the U.S. are vaccinated in their first year of life with DPT vaccine (against diptheria, pertussis, and tetanus); however, in poor developing countries, immunization is not routine and presents a hazard for these countries as well as for nonimmunized people who travel to these countries. SUGGESTED PRODUCTS: Echinacea Root Tincture 2 fl. oz., 100% Organic Used as a blood cleanser and especially for skin disorders, such as boils and abcesses considered a valuable alternative to antiobiotics; This herb has very strong immune-activating abilities it activates the white blood cells to fight off both bacterial and viral infections. Retail: $17.99 Our Low price: Antibiotic Tincture 2 fl. oz., 100% Organic Abscesses; Acne; Arthritis; Auto-immune Diseases; Bladder; Breast Cancer/Tumors; Bronchial (Bronchitis); Burns; Cancer; Chicken Pox; Cold Sores; Colds; Colitis; Diptheria; Disinfectant; Ear - Aches; Infection; Hearing; Fever; Glands - Infection. Retail: $17.99

43. Diptheria Article - Suite101.com messages from 1 to 1 of Discussions relating to Microbiology diptheriaarticle - dewey decimal 579. diptheria article. Go To 1 to Latest, http://www.suite101.com/discussion.cfm/microbiology/68317/latest/1

Topics Articles Links BEST OF WEB ONLINE COURSES COMMUNITIES BOOK CIRCLE ... MY SUITE Search Within: Microbiology Environment Suite101.com Member Central Join Our Community! Login Member Update What's New ... TravelSuite Suite University About Suite University Visit the University Course Listing New Courses ... Featured Courses New Topics Teaching Creative Writing to Children Maine People Organic Vegetable Gardening African-American Home Schooling ... More... Suite Events My Favorite Place War and Peace Spring Into Health! Earth Day 2003 More about Suite101 About Suite101.com - Select a related topic - Aquatic Animals Arctic Wildlife Backyard Birdwatching Alm Birding Colorado Nature Series Conservation and Consumpt Everyday Geology Firefighting Living With Nature Living with Wildlife Lizards, Turtles and Snak Microbiology Paleontology Pennsylvania Nature Science of the Sky Snails and Shells Tropical and Neotropical Weeds and Wild Things Wild Cats Wildlife - Select a related course - Ecological Gardening: Org Environmental affairs - G Our National Wildlife Tre Visit Environment Detailed Topic List Home Science and mathematics ... Microorganisms, fungi, algae

44. Targeting Breast Cancer Using Diptheria Toxin Targeting Breast Cancer Using diptheria Toxin. Senyon Choe, Ph. D. TheSalk Institute for Biological Studies Award Type ITaMoCA, Innovative http://www.ucop.edu/srphome/bcrp/progressreport/abstracts/innov/2CB-0063.html

Targeting Breast Cancer Using Diptheria Toxin Senyon Choe, Ph. D. The Salk Institute for Biological Studies Award Type: ITaMoCA, Innovative Treatments Modalities Duration: 2 yrs., 1996-1998 Initial Award Abstract Normally, the growth of human breast cells is closely controlled by the levels of hormones (such as estrogen) and growth-promoting proteins (such as heregulin). Heregulins are a class of proteins known to promote the unwanted growth of breast cancer cells under certain conditions. The overabundance of heregulin on the surface of breast cancer cells often indicates that the cancer has progressed to the stage that the cells are no longer responsive to estrogen treatment using a drug like tamoxifen. The counter balancing activities of these two classes of molecules, steroid hormones and growth-promoting proteins, are important in determining the progression of breast cancer. The ultimate goal of this proposal is to disrupt this balance in order to stop growth of breast cancer cells. In practice, our specific aim is to design a toxin protein that will kill cells carrying the growth-promoting protein heregulin. Diphtheria toxin is known to kill certain types of cells carrying a specific receptor protein on their surface. This toxin will serve as the starting material in our design of a new toxin for killing breast cancer cells. Our strategy is to create a toxin variant that is capable of recognizing and killing only those cancer cells carrying heregulin. We hypothesize that the targeted delivery of this toxin variant to these cells will effectively reduce the overall growth of breast cancer.

45. DIPTHERIA IN THE FORMER SOVIET UNION 24.01.99, diptheria IN THE FORMER SOVIET UNION, News. Medscape http//www.medscape.com/govmt/CDC/EID/1998/v04.n04/e0404.04.vite/pnte0404.04.vite.html http://www.vaccinetwork.org/archivio/difterite/1999/24.01.99.html

DIPTHERIA IN THE FORMER SOVIET UNION News Medscape http://www.medscape.com/govmt/CDC/EID/1998/v04.n04/e0404.04.vite/pnt-e0404.04.vite.html Diphtheria in the Former Soviet Union: Reemergence of a Pandemic Disease Charles R. Vitek and Melinda Wharton, Centers for Disease Control and Prevention, Atlanta, Georgia, USA [Emerging Infectious Diseases 4(4):539-550, 1998. Centers for Disease Control] Abstract The massive reemergence of diphtheria in the Newly Independent States of the former Soviet Union marked the first large-scale diphtheria epidemic in industrialized countries in 3 decades. Factors contributing to the epidemic included a large population of susceptible adults; decreased childhood immunization, which compromised what had been a well-established childhood vaccination program; suboptimal socioeconomic conditions; and high population movement. The role of a change in the predominant circulating strains of Corynebacterium diphtheriae in this epidemic remains uncertain. Massive, well-coordinated international assistance and unprecedented efforts to vaccinate adults were needed to control the epidemic. Introduction In the 1990s, a massive epidemic throughout the Newly Independent States of the former Soviet Union marked the reemergence of epidemic diphtheria in industrialized countries. Diphtheria had been well controlled in the Soviet Union for more than 2 decades after universal childhood immunization was initiated in the late 1950s (Figure 1). Although all of the Newly Independent States were affected, three quarters of the more than 140,000 cases (Table 1) and two thirds of the more than 4,000 deaths reported since 1990[1-3] were reported by the Russian Federation.

46. Loyola Univ. Health Sys. - Infectious Disease - Diptheria Maps, You are here Home Health Information Health Topics InfectiousDiseases diptheria Diphtheria What is diphtheria? Diphtheria http://www.luhs.org/health/topics/infectious/diptheri.htm

You are here: Home Health Information Health Topics Infectious Diseases Diphtheria What is diphtheria? Diphtheria is an acute bacterial disease that can infect the body in two areas: the throat (respiratory diphtheria) and the skin (skin or cutaneous diphtheria). A common childhood disease in the 1930s, a vaccine against diphtheria has made it very rare in the US and other developing countries today. What are the symptoms of diphtheria? respiratory diphtheria When a person is infected with diphtheria, the bacterium usually multiplies in the throat, leading to the respiratory version of diphtheria. A membrane may form over the throat and tonsils, causing a sore throat. Other common symptoms of respiratory diphtheria may include: breathing difficulty husky voice enlarged lymph glands increased heart rate Persons may die from asphyxiation when the membrane obstructs breathing. Other complications of respiratory diphtheria are caused by the diphtheria toxin released in the blood, leading to heart failure.

47. Diptheria diptheriaPertussis Tetanus (DPT) Vaccine. Click here for generalinformation about the DPT vaccine. ITCP following DPT vaccination http://www.micro.unsw.edu.au/MICR3051 2001/Burgess, Russell, Brady, Morton/Rebec

Diptheria-Pertussis Tetanus (DPT) Vaccine Click here for general information about the DPT vaccine ITCP following DPT vaccination has been rarely documented; only two papers outline these cases (9). In particular, Arya et. al. introduce two patients that presented with ITCP exhibiting a variety of symptoms, at three days after the first booster vaccine; and eight days after the first dose of vaccine and with each subsequent booster, respectively (9). Back to Main Page

48. Immunizations - Tetanus-Diptheria Immunizations. Tetanusdiptheria. This vaccine protects against lockjaw .This vaccine is especially important if your hobby or job http://www.the-health-pages.com/preventive/i_tet.html

Immunizations Tetanus-Diptheria This vaccine protects against "lockjaw". This vaccine is especially important if your hobby or job is gardening or yard work where most dirty cuts happen. Though rare, tetanus can be fatal. Not At High Risk At High Risk Every 10 years Every 10 years At High Risk if you: do a lot of work in the yard; have a job doing gardening or farming. Lifestyle Health Risk Factors Services and Self Care Should you or your group be a part of The-Health-Pages? See how easy it is to join. The-Health-Pages

49. Preventable Diseases - What Is Diptheria? Immunization Preventable Diseases What is Diphtheria? Diphtheria isa very serious disease that can make a person unable to breathe http://www.immunize-ohio.org/dis_dipth.html

Immunization - Preventable Diseases What is Diphtheria? Diphtheria is a very serious disease that can make a person unable to breathe, cause paralysis (when a person cannot move some muscles) or heart failure. It is spread by coughing and close contact. About one of every 10 people who get diphtheria dies from it. Fortunately, only a few cases were reported in the United States during the past few years, but larger outbreaks continue to occur in other areas of the world. Last Updated: 5/5/00

50. Guardian Century | 1920-1929 | New Vaccines For Tetanus And Diptheria New vaccines for tetanus and diptheria French discovery Immunity claimed forinfants Wednesday January 27, 1926 Vaccines against diphtheria and tetanus http://www.guardiancentury.co.uk/1920-1929/Story/0,6051,126691,00.html

Go to: Guardian Unlimited home UK news World news Archive search Arts Books Business EducationGuardian.co.uk Film Football Jobs MediaGuardian.co.uk Money The Observer Online Politics Shopping SocietyGuardian.co.uk Sport Talk Travel Audio Email services Special reports The Guardian The weblog The informer The northerner The wrap Advertising guide Crossword Dating Headline service Syndication services Events / offers Help / contacts Information Newsroom Style guide Travel offers TV listings Weather Web guides Guardian Weekly Money Observer Home Talk Search Enter year New vaccines for tetanus and diptheria Wednesday January 27, 1926 "Vaccines" against diphtheria and tetanus, comparable as prophylactics with Jenner's vaccine against smallpox, have been discovered at the Pasteur Institute here by a French chemist, M. G. Ramon. They are harmless, do not cause the slightest reaction, and confer an immunity even more lasting than that of calf-lymph against small-pox. It is suggested that all infants over twelve months' old should henceforth go through a second vaccination for diphtheria, and that all soldiers on active service should be vaccinated against tetanus, as they are now against typhus. A generation ago Dr. Roux, the friend and successor of Pasteur, discovered specific serums against diphtheria and tetanus, but the immunising effect of injections in both cases has been extremely ephemeral, lasting only, at the most, a few days. M. Ramon set himself to find something that would be as good as if not better than Jenner's vaccine.

51. Ashley Vet Clinic - Calf Diptheria Calf diptheria (necrotic laryngitis) is an infection of the larynx (voicebox)of cattle caused by the same bacteria that causes bovine footrot. http://www.ashleyvet.com/html/calfdiptheria.htm

Calf diptheria (necrotic laryngitis) is an infection of the larynx (voicebox) of cattle caused by the same bacteria that causes bovine footrot. Calves with diptheria usually have a sudden onset of labored breathing and a "honking" noise when they breathe. This "honking" is due to a narrowed airway that results form the infection and inflammation. Diptheria is often mistaken for pneumonia. Treatment for diptheria consists of antibiotics and anti-inflammatories and must be continued for several days beyond clinical signs in order to prevent relapses. Generally we use a combination of sulfa (either Albon or Bovazine), Dexamethasone and Micotil. When relapses do occur the disease becomes much more difficult to treat and the prognosis is much poorer. Occasionally surgical intervention is necessary on chronic cases. Our treatment goal is to avoid surgery if possible. A full course of treatment takes at least five days.

52. EHS: Mosby's Drug Consult - Drug Updates - Diptheria And Tetanus Toxoids And Ace Contact Us diptheria and Tetanus Toxoids and Acellular Pertussis Adsorbed / HepatitisB (Recombinant) and Inactivated Poliovirus Vaccine Combined 003581. http://www.mosbysdrugconsult.com/DrugConsult/003581.html

Drug Consult Home Log In Drug Updates Description ... Contact Us Diptheria and Tetanus Toxoids and Acellular Pertussis Adsorbed / Hepatitis B (Recombinant) and Inactivated Poliovirus Vaccine Combined 003581 Categories: Pregnancy Category C; FDA Approved 2002 Dec Brand Names: Pediarix Description Note: The trade name has been used throughout this monograph for clarity. Pediarix [diphtheria and tetanus toxoids and acellular pertussis adsorbed, hepatitis B (recombinant) and inactivated poliovirus vaccine combined] is a noninfectious, sterile, multivalent vaccine for intramuscular administration manufactured by SmithKline Beecham Biologicals. It contains diphtheria and tetanus toxoids, 3 pertussis antigens (inactivated pertussis toxin [PT], filamentous hemagglutinin [FHA], and pertactin [69 kiloDalton outer membrane protein]), hepatitis B surface antigen, plus poliovirus Type 1 (Mahoney), Type 2 (MEF-1), and Type 3 (Saukett). The diphtheria toxoid, tetanus toxoid, and pertussis antigens are the same as those in Infanrix (diphtheria and tetanus toxoids and acellular pertussis vaccine adsorbed). The hepatitis B surface antigen is the same as that in Engerix-B [hepatitis B vaccine (recombinant)]. The diphtheria toxin is produced by growing Corynebacterium diphtheriae in Fenton medium containing a bovine extract. Tetanus toxin is produced by growing

53. Notifiable Condition: Diptheria DOH Logo linking to the DOH Home Page, You are here DOHHome » Notifiable Conditions » Diphtheria Index, http://www.doh.wa.gov/notify/nc/diphtheria.htm

You are here: DOH Home Notifiable Conditions » Diphtheria Index Search Employees Site Directory: Notifiable Conditions: Diphtheria Other links concerning Notifiable Conditions Local Health Jurisdictions How to Report a Notifiable Condition Glossary Legal Requirements ... EpiTrends Posters PDF documents require the free Acrobat Reader. Click here to download a copy Diphtheria Diphtheria in Washington State The last case of toxigenic diphtheria reported in Washington occurred in 1979. Cases are most often associated with travel as diphtheria is not endemic to Washington. Purpose of Reporting and Surveillance To alert public health authorities to the presence of C. diphtheria and the possibility of other cases developing in the area, a particular concern given the large number of susceptible adults. To assist in the diagnosis of cases.

54. Notifiable Condition: Diptheria DOH Logo linking to the DOH Home Page, You are here DOHHome » Notifiable Conditions » Diphtheria Guidelines, http://www.doh.wa.gov/notify/guidelines/diphtheria.htm

You are here: DOH Home Notifiable Conditions » Diphtheria Guidelines Search Employees Site Directory: Other links concerning Notifiable Conditions Local Health Jurisdictions How to Report a Notifiable Condition Glossary Legal Requirements ... EpiTrends Posters Surveillance and Reporting Guidelines for Diphtheria back to Diphtheria index page Disease Reporting In Washington The last case of toxigenic diphtheria reported in Washington occurred in 1979. Cases are most often associated with travel as diphtheria is not endemic to Washington. Purpose of Reporting and Surveillance To alert public health authorities to the presence of C. diphtheria and the possibility of other cases developing in the area, a particular concern given the large number of susceptible adults. To assist in the diagnosis of cases.

55. Diptheria & Tetanus - Public Health Disease Prevention. (641) 4219321. Diphtheria, Tetanus and Pertussis Vaccine (DTaP).Why Get Vaccinated? Diphtheria, Tetanus, and Pertussis are serious diseases. http://www.cghealth.com/webdocs/dp_diptheria.htm

Disease Prevention Diphtheria, Tetanus and Pertussis Vaccine (DTaP) Why Get Vaccinated? Diphtheria, Tetanus, and Pertussis are serious diseases. Diphtheria causes a thick covering in the back of the throat and can lead to breathing problems, paralysis, heart failure and even death. Tetanus (lockjaw) causes painful tightening of the muscles, usually all over the body. It can lead to "locking" of the jaw that cannot be opened nor can the person swallow. Tetanus can lead to death. Pertussis (whooping cough) causes coughing spells so bad that it is hard for infants to eat, drink or breathe. These can last for weeks. It can lead to pneumonia, seizures, brain damage, and death. What are the Risks? As with any drug or vaccine, there is a rare possibility that an allergic reaction could occur. If there are reactions, they usually start within three days and don't last long. Most people have no serious reaction to these vaccines. With DTaP vaccine, reactions are much less likely to happen than with DTP vaccine which was given several years ago.

56. Victorian Llanfyllin - A Child Dies Of Diptheria The most common of the illnesses mentioned in school Log Books were scarlet fever,measles, whooping cough and diptheria. 17 November Death from diptheria. http://multiweb.ruralwales.net/~history/history.powys.org.uk/school1/llanfyllin/

[an error occurred while processing this directive]Llanfyllin and district Victorian school days [an error occurred while processing this directive] The death of little Annie Davies Drawing by Rob Davies Schools in Victorian times always went in fear of infectious diseases which could spread rapidly when children from a wide area came together in the schoolroom. The most common of the illnesses mentioned in school Log Books were scarlet fever, measles, whooping cough and diptheria . Some diseases could be killers, and could become very serious very quickly. The example on this page is from Bwlchycibau School in Poor little Annie Davies was absent from school with a sore throat which led to her funeral just 8 days later ! 13th November 17th November 21st November These entries from the 1896 school Log Book read - 13 November "Annie Davies, and Mabel Owen are ill suffering from sore throats and cold". 17 November "Death from Diptheria. Annie Davies, the scholar mentioned above, died this morning".

57. Mrs Winterton Caught Diptheria In The 1920s; How Did She Manage In Hospital? Mrs Winterton caught diptheria in the 1920s; how did she manage in hospital? http://www.the-book.com/winterton.html

Mrs Winterton caught diptheria in the 1920s; how did she manage in hospital?

58. 2001-2002 Tetanus Diptheria (Td) Vaccine Shortage Alert 20012002 Wisconsin Tetanus diphtheria (Td) Vaccine Shortage Alert. pdf versionof this file. Date April 13, 2001. To Physicians. Local Health Departments. http://www.dhfs.state.wi.us/immunization/01_02_Td_V_Shrt.htm

Licensing Reference Center Search Immunization Home Page ... Relevant Links 2001-2002 Wisconsin Tetanus diphtheria (Td) Vaccine Shortage Alert pdf version of this file Date: April 13, 2001 To: Physicians Local Health Departments Pharmacists Hospitals ERs Urgent / Immediate Care Facilities International travel clinics APNs and PAs Recreational/Educational Camps From: Jeffrey P. Davis, MD Chief Medical Officer and State Epidemiologist for Communicable Diseases Thomas N. Saari, MD Chair, Wisconsin Council on Immunization Practices Subject: Tetanus diphtheria (Td) Vaccine Shortage Alert There is a shortage of Td vaccine in the United States that, according to the Centers for Disease Control and Prevention (CDC), is expected to last 12-18 months. The Wisconsin Immunization Program has on hand only 19% of the projected doses needed until the next shipment arrives in September 2001. To assure an equitable distribution of Td vaccine, health care providers enrolled in the Vaccines For Children (VFC) Program can request a maximum of 30 doses per order. Frequent orders will be evaluated for justifiability. Non-VFC enrolled providers in need of Td vaccine for wound management should call Aventis Pasteur at 1-800-Vaccine (1-800-822-2463). To conserve Td vaccine for those person 7 years of age who are at greatest risk of exposure to tetanus bacteria or diphtheria disease, all providers of Td vaccine are requested to prioritize its use based on the following recommendations of the Advisory Committee on Immunization Practices (ACIP) and the Wisconsin Council on Immunization Practices (WCIP):

59. Newly Approved Drug Therapies (43): Tripedia (Diptheria And Tetanus Toxoids And Listing for Tripedia (diptheria and Tetanus Toxoids and Acellular Pertussis VaccineAbsorbed) in FDA Approved Drug Therapies Archives from CenterWatch Clinical http://www.centerwatch.com/patient/drugs/dru43.html

Drugs Approved by the FDA Drug Name: Tripedia (Diptheria and Tetanus Toxoids and Acellular Pertussis Vaccine Absorbed) The following information is obtained from various newswires, published medical journal articles, and medical conference presentations. Company: Connaught Laboratories Approval Status: Approved August 1996 Treatment for: whooping cough General Information Tripedia has been approved as an injected whooping cough vaccine for children up to three years of age. Whooping cough, or pertussis, is a highly contagious disease that usually hits children under age three, causing severe coughing and difficulty in breathing. Tripedia is made of just a portion of the killed pertussis bacteria. This acellular vaccine has also been approved in the United States for booster shots in older children, and it has been used for 15 years in Japan for children of all ages. American infants will be given this acellular vaccine at ages two, four and six months as well as booster shots later. Clinical Results A large-scale phase III efficacy study was conducted in Germany from 1993 to 1995 and enrolled 16,780 infants between six and 17 weeks of age. Tripedia was administered to 12,517 of the infants. The efficacy of the acellular pertussis vaccine in the German case-control study was 80% for culture-confirmed pertussis cough of 21 days.

60. Diptheria - What You Need To Know Children in the USA are commonly immunized with diptheria toxoid 3 doses usuallygiven at 2, 4, and 6 months of age, with a booster at 1 and 6 years of age. http://www.csc.liv.ac.uk/~u1idn/

DIPHTHERIA - (Corynebacterium diphtheriae) What does it affect? Causes History Symptoms ... Immunization Causes of "diphtheria" Bacteria: Microscopic rod shaped infectious bacteria Diphtheria is found only in humans and is usually transmitted by respiratory droplets from infected persons. It can however, be transmitted by contaminated objects or foods. The incubation period is 2 to 5 days. What does diphtheria affect? throat larynx upper respiratory airways History Years ago, diphtheria was a widespread and greatly feared disease. Through the 1920's it struck about 150,000 people a year, and killed about 15,000 of them. Since then, these figures have dropped considerably, thanks to parents who have gotten their children immunized against this terrible disease. There were only 918 cases in 1960, 435 in 1970, and 128 in 1976. Today, only a few cases occur each year. Diphtheria is caused by a germ that lives in the mouth, throat, and nose of an infected person. It is easily passed to others through coughing or sneezing. Symptoms Thick, gray, and attached membrane over the tonsils and throat, also:

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