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         Dysmenorrhea:     more books (57)
  1. Ibuprofen: International Nonproprietary Name, Non-steroidal anti-inflammatory drug, Trademark, Nurofen, Advil, Arthritis, Dysmenorrhea, Fever, Analgesic, Inflammation, Antiplatelet drug
  2. Premenstrual Syndrome and Dysmenorrhea
  3. Factors relating to dysmenorrhea: A discriminative function analysis (Carson-Newman College) by Vanessa Jan Harrison, 1978
  4. A physiologic treatment of congestive dysmenorrhea and kindred disorders associated with the menstrul function by Clelia Duel Mosher, 1914
  5. Dysmenorrhea
  6. Dysmenorrhea in young girls by J Ghrist, 1912
  7. Gale Encyclopedia of Medicine: Menstrual disorders by Debra Gordon, 2002-01-01
  8. These three essential oils that reduce menstrual cramps benefit women of all ages.: An article from: Women's Health Letter by Gale Reference Team, 2007-02-01
  9. Don't cramp my style.(Body Language)(menstrual cramps): An article from: New Moon by Shannon Weary, 2003-09-01
  10. Menstrual Disorders: An entry from Gale's <i>Gale Encyclopedia of Medicine, 3rd ed.</i> by Debra Gordon, Rebecca, PhD Frey, et all 2006
  11. Danggui-Shaoyao-San, a traditional Chinese prescription, suppresses [PGF.sub.2.[alpha]] production in endometrial epithelial cells by inhibiting COX-2 ... Journal of Phytotherapy & Phytopharmacology by Y.Q. Hua, S.L. Su, et all 2008-12-01
  12. Black haw: An entry from Thomson Gale's <i>Gale Encyclopedia of Alternative Medicine</i> by Judith Turner, 2001
  13. Gale Encyclopedia of Alternative Medicine: Menstruation by Belinda Rowland, 2001-01-01
  14. Kick cramps to the curb: parting with period pain.(Body Language): An article from: New Moon by Gabby Quintana, 2008-01-01

41. Contraception Online Slides - Primary+dysmenorrhea, Primary Dysmenorrhea, Adoles
Search Slides. Index of Slide Contents. search primary dysmenorrhea results4. 1 Slide Title. Primary dysmenorrhea Incidence. Talk. Adolescents and OCs.
http://www.contraceptiononline.org/slides/slide01.cfm?q=primary dysmenorrhea

42. Homeopathic Remedies For Dysmenorrhea (Painful Menstruation)
dysmenorrhea (Painful Menstruation). Also indexed as Menstruation (Painful
http://a-wellness-trend.royalbodycare.com/HealthNotes/Homeo/Dysmenorrhea_hm.htm
Dysmenorrhea (Painful Menstruation) Also indexed as: Menstruation (Painful)
What Is Homeopathy?
Belladonna: Symptoms that are very intense and come and go suddenly, accompanied by a feeling of heat, often indicate a need for this remedy. The menstrual flow is typically bright red, profuse, and may have begun too early. Pain and cramping are worse from jarring and from touch, yet applying steady pressure often brings relief. Walking or bending over can make things worse, and sitting may be the most tolerable position. A woman who needs this remedy may feel restless and flushed, with pulsing or pounding sensations, and eyes that are sensitive to light. Bovista: Women needing this remedy tend to have problems with puffiness and edema during times of menstrual stress, and can feel very awkward and clumsy. Pain may be felt in the pelvic region, often with soreness near the pubic bone. Menstrual flow increases at night (and may even be absent during the day). Diarrhea occurring at the time of the menstrual period is a strong indication for this remedy. Caulophyllum: Women with a history of weak uterine tone and irregular periods may find some relief in this remedy. Intense discomfort during periods, with drawing pains in the thighs and legs as well as the pelvic area, are strong indications. The woman may experience a heavy flow of blood or other discharge. Stiffness or arthritis, especially in the finger-joints, may be seen in a person who needs this remedy.

43. Dysmenorrhea - Acupuncture.com
Key Diagnostic Points The pain in the lower abdomen appears withthe menstrual cycle. The pain can spread over the whole abdomen
http://acupuncture.com/Clinical/Dysmen.htm
Dysmenorrhea
Homepage Back
Key Diagnostic Points:
  • The pain in the lower abdomen appears with the menstrual cycle.
  • The pain can spread over the whole abdomen, the lumbo-sacral region, or there is dragging pain in the vulva and anus. It varies in degrees and can be relieved when the menstrual blood flows smoothly.
  • Pain beginning before or during the period suggests excess.
  • Pain beginning at the end or after the period suggests deficiency.
  • Pressure making the pain worse suggests excess.
  • Pressure making the pain better suggests deficiency.
    Differential Diagnosis:
    Stagnation of Qi and Blood Lower abdominal pain during, or one to two days before, the period, feelings of distention and tenderness in the abdomen and breasts, hesitant start of menstrual flow, pain relieved after passing clots, pre-menstrual tension and irritability. Blood: Dark with clots
    Tongue: Purple body with purple spots
    Pulse: Wiry Stagnation of cold
    Lower abdominal pain several days before the period or during the period. Pain relieved by the application of heat, feelings of cold in the abdomen, and sore back. Blood: Scanty, dark, with clots
  • 44. CSHC - Dysmenorrhea
    CSHC logo, dysmenorrhea (Painful Menstrual Cramps). What causes dysmenorrhea?The exact cause of dysmenorrhea is still unknown, but
    http://healthcenter.ucdavis.edu/htdysmenorrhea.html
    Dysmenorrhea (Painful Menstrual Cramps)
    Cowell Home
    Health Education
    Program
    Health Topics ...
    Index
    Dysmenorrhea What is it?
    Dysmenorrhea is the medical name for the pain of severe and disabling menstrual cramps. Approximately 52% of women are affected by dysmenorrhea and about 10% of these are incapacitated each month for up to three days. The pain usually starts as menstruation starts, but mild cramping or lower abdominal pain may begin 24 to 48 hours before the flow begins. It may last only a few hours until the flow is well-established, but some women are troubled for several days. What causes Dysmenorrhea?
    The exact cause of dysmenorrhea is still unknown, but a group of substances called prostaglandins have been the focus of recent attention. Prostaglandins are produced by the lining of the uterus and cause the muscle wall of the uterus to contract, producing the type of pain most women with dysmenorrhea have. Women with severe cramps appear to produce more of these chemicals than women with mild or no cramps, especially just before and on the first day of their periods. Are there other symptoms?

    45. Amenorrhea
    Menstrual Cramps dysmenorrhea. Book, 10%. Types of dysmenorrhea Primarydysmenorrhea (90%) Onset occurs within 6 to 12 months of Menarche;
    http://www.fpnotebook.com/GYN149.htm
    Home About Links Index ... Editor's Choice Paid Advertisement (click above). Please see the privacy statement Gynecology Symptom Evaluation Breast ... Menses Amenorrhea Abnormal Uterine Bleeding Menstrual Cramps Assorted Pages Acute Pelvic Pain Acute Pelvic Pain Causes Chronic Pelvic Pain Chronic Pelvic Pain Causes ... Vulvar Vestibulitis Amenorrhea Book Home Page Cardiovascular Medicine Dental Dermatology Emergency Medicine Endocrinology Gastroenterology General Medicine Geriatric Medicine Gynecology Hematology and Oncology HIV Infectious Disease Jokes Laboratory Neonatology Nephrology Neurology Obstetrics Ophthalmology Orthopedics Otolaryngology Pediatrics Pharmacology Prevention Psychiatry Pulmonology Radiology Rheumatology Sports Medicine Surgery Urology Chapter Gynecology Index Breast Cervix Contraception Dermatology Endocrinology Examination Hematology and Oncology Infectious Disease Laboratory General Menses Obstetrics Pharmacology Prevention Procedure Psychiatry Radiology Surgery Symptom Evaluation Uterus Vagina Vulva Page Symptom Evaluation Index Breast Mastalgia Breast Nipple Discharge Breast Nipple Discharge Galactorrhea Endo Hot Flashes Menses Amenorrhea Menses DUB Menses Dysmenorrhea Pelvic Pain Acute Pelvic Pain Acute Causes Pelvic Pain Chronic Pelvic Pain Chronic Causes Pelvic Pain Chronic Causes Congestion Pelvic Pain Chronic Causes Psychomotor Pelvic Pain Chronic Management Sexual Dyspareunia
  • Primary Amenorrhea No menstrual period by: Sixteen years old or One year beyond Family History No secondary sexual characteristics by 14 years old
  • 46. Primary Dysmenorrhea
    Secondary dysmenorrhea, Book, Home Causes of secondary dysmenorrhea (pelvicpathology) Pelvic Inflammatory Disease (PID); Endometriosis;
    http://www.fpnotebook.com/GYN77.htm
    Home About Links Index ... Editor's Choice Paid Advertisement (click above). Please see the privacy statement Gynecology Menses Assorted Pages Primary Amenorrhea Secondary Amenorrhea Abnormal Uterine Bleeding Causes Anovulatory Bleeding ... Uterine Fibroid Primary Dysmenorrhea Book Home Page Cardiovascular Medicine Dental Dermatology Emergency Medicine Endocrinology Gastroenterology General Medicine Geriatric Medicine Gynecology Hematology and Oncology HIV Infectious Disease Jokes Laboratory Neonatology Nephrology Neurology Obstetrics Ophthalmology Orthopedics Otolaryngology Pediatrics Pharmacology Prevention Psychiatry Pulmonology Radiology Rheumatology Sports Medicine Surgery Urology Chapter Gynecology Index Breast Cervix Contraception Dermatology Endocrinology Examination Hematology and Oncology Infectious Disease Laboratory General Menses Obstetrics Pharmacology Prevention Procedure Psychiatry Radiology Surgery Symptom Evaluation Uterus Vagina Vulva Page Menses Index Amenorrhea Primary Amenorrhea Secondary DUB Causes DUB Management Anovulatory DUB Management Anovulatory Metrorrhagia DUB Management Ovulatory DUB Management Ovulatory Menorrhagia Dysmenorrhea Primary Dysmenorrhea Secondary
  • Epidemiology Menarche Pathophysiology Uterine hyperactivity Increased frequency of uterine contractions Dysrhythmia of uterine contractions Increase in enzyme Prostaglandin Synthetase Increased prostaglandins result in vasoconstriction Uterine hypoxia (uterine Angina Symptoms See Dysmenorrhea Management Nonsteroidal Anti-inflammatory drugs ( NSAID S) Ibuprofen Motrin ) 400 to 800 mg PO tid to qid
  • 47. Dysmenorrhea
    dysmenorrhea. Also found under Menstrual Disorders. dysmenorrhea is the term usedto describe painful menstrual periods. There are two types of dysmenorrhea.
    http://www.hmc.psu.edu/healthinfo/d/dysmenorrhea.htm

    48. Dysmenorrhea
    WHAT IS IT? dysmenorrhea (menstrual cramps or painful periods) is a feeling of physicaldiscomfort that occurs immediately before or during menstrual periods.
    http://www.barnard.columbia.edu/health/publications/dysmenorrhea.htm

    WHAT IS IT? Dysmenorrhea (menstrual cramps or painful periods) is a feeling of physical discomfort that occurs immediately before or during menstrual periods. WHAT CAUSES IT? Researchers believe that menstrual cramps are influenced by prostaglandins, which are chemicals normally produced in the body. Too much prostaglandin may lead to excess cramping of the uterus, which results in pain. WHAT ARE ITS COMMON SYMPTOMS? The following is a list of frequently mentioned complaints: lower abdominal discomfort and fullness, backache, leg and/or thigh aches, headache, nausea, diarrhea, bloating, dizziness, irritability, fatigue, pelvic fullness or heaviness. HOW LONG WILL IT LAST? Menstrual cramps and other menstrual discomforts usually begin 12-24 hours prior to, or on, the day of the onset of menstrual flow. For most women the symptoms last only a day or two. For others, the symptoms may last throughout the period (5 to 7 days). Some women have the same kinds of menstrual discomfort with every period but for other women the symptoms may change from month to month. IS IT CONTAGIOUS?

    49. Painful Menstruation (Dysmenorrhea)
    dysmenorrhea, or painful menstruation, is classified as either primaryor secondary. dysmenorrhea. Also indexed as Painful Menstruation.
    http://www.hollandandbarrett.com/Concern/Dysmenorrhea.htm
    Dysmenorrhea Also indexed as: Painful Menstruation Dysmenorrhea, or painful menstruation, is classified as either primary or secondary. Primary dysmenorrhea generally occurs within a couple of years of the first menstrual period. The pain tends to decrease with age and very often resolves after childbirth. Secondary dysmenorrhea is commonly a result of endometriosis, starts later in life, and tends to increase in intensity over time. As many as half of menstruating women are affected by dysmenorrhea, and of these, about 10% have severe dysmenorrhea, which greatly limits activities for one to three days each month. Conventional treatment options: Conventional treatment includes pain medications such ibuprofen paracetamol Oral contraceptives may also be used to suppress ovulation. In cases of severe nausea and vomiting, anti-nausea medicines may be recommended. Lifestyle changes that may be helpful: Many women feel the need to lie still while experiencing menstrual cramps, while others find that exercise helps relieve the pain of dysmenorrhea. This variation from woman to woman may explain why some researchers report that exercise makes symptoms worse, though most studies report that exercise appears helpful.

    50. Primary Dysmenorrhea - AnsMe.com Dictionary (define)
    Dictionary primary dysmenorrhea. Definition for primary dysmenorrhea.primary dysmenorrhea (noun) -. 1. painful menstruation that
    http://define.ansme.com/words/p/primary_dysmenorrhea.html
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    ... primary sex character... Dictionary - primary dysmenorrhea Show Definition Sounds Similar Relations Rhymes Translate Definition for primary dysmenorrhea primary dysmenorrhea (noun) painful menstruation that is intrinsic to menstruation and not the result of a disease Source: WordNet ® 1.7, © 2001 Princeton University All other brands are property of their respective owners. Directory Dictionary AIM Smileys Contact Us

    51. Dysmenorrhea
    Counseling Sheets. dysmenorrhea. Painful The reason for noncompliance willbecome obvious as the causes of dysmenorrhea are discussed. One
    http://www.ucheepines.org/dysmenorrhea.htm
    DYSMENORRHEA Painful menstruation is difficult to treat, not because the disorder will not yield to therapy, but because women have about the worst record of noncompliance to medical counsel with this disorder that with any other. The reason for noncompliance will become obvious as the causes of dysmenorrhea are discussed. One important cause of dysmenorrhea is that of wearing improper clothing. Tight bands around the waist, hips, or thighs impede the circulation to the pelvic organs and increase the likelihood of painful menstruation. Also, the clothing of the extremities must be proper. There should not be one inch of chilled skin on the extremities any time during the month, not only during the menstrual period itself. The extremities should be covered with as many layers of clothing as is the trunk. To fail to do so is to cause the circulation to be imbalanced, and increases the likelihood of pelvic congestion and painful menstruation. Most American women do not get sufficient exercise; this fact is second only to improper clothing in the causation of dysmenorrhea. A study showed that 75% of a group of 5,000 junior high school girls were either cured or had definite improvement of menstrual discomfort with simple bending and stretching exercises. The first exercise was stretching, done by touching the fingers to the ankles with the knees held straight. The second exercise was thrusting the leg backward as the arms were swung high over the head. These two exercises performed 4-10 times daily, four times weekly for several weeks resulted in a 75% improvement rate. In our experience, one hour of useful vigorous labor out-of-doors daily has been more effective in curing dysmenorrhea than have calisthenics.

    52. Dysmenorrhea: Products And Research - GreenCanyon.com: Better Health Just A Clic
    dysmenorrhea Research and Products. For the best prices on the highest qualityproducts, come visit us at www.GreenCanyon.com. dysmenorrhea DESCRIPTION.
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    Now Only: 6.99 US True Companions - Beanbag Hug-Bears / SM Now Only: 6.15 US LEGO Duplo: Wallpaper Wendy Now Only: 4.75 US "Great things are done when men and mountains meet." - William Blake Dysmenorrhea DESCRIPTION Painful menstruation. RELATED PRODUCTS Barberry Belladonna Blue Cohosh Chamomilla ... 2 OZ $4.76 US ($0.060 per Pellet) $16.42 US ($16.420 per oz) $14.99 US ($14.990 per oz) $17.13 US ($8.565 per oz) Magnesia Phosphorica 30C 4g, 80 Pellets $4.76 US ($0.060 per Pellet) All Prices in US$. Click Flag For CDN$. The information provided at GreenCanyon.com is for educational purposes only and is not intended for self-diagnosis nor self-treatment of conditions that should be managed by a qualified health care provider. Unless otherwise indicated, research, ailment and product information have not been evaluated by the US Food and Drug Administration ("FDA") or Health Canada. Better Health Just A Click Away!

    53. Dysmenorrhea
    dysmenorrhea (Menstrual Cramps), BASIC INFORMATION Primary dysmenorrhea meanspain has recurred regularly since periods began. Secondary dysmenorrhea
    http://www.siu.edu/~shp/WebEd/Dysmenorrhea.htm
    DYSMENORRHEA (Menstrual Cramps) BASIC INFORMATION
    DESCRIPTION

    Severe, painful cramps during menstruation. Primary dysmenorrhea means pain has recurred regularly since periods began. Secondary dysmenorrhea means pain began years after periods started. Women with dysmenorrhea are generally fertile. Severity of symptoms varies greatly from woman to woman, and from one time to the next in the same woman. Dysmenorrhea usually is less severe after a woman has a baby. FREQUENT SIGNS AND SYMPTOMS
    Cramping and sometimes sharp pains in the lower abdomen, lower back and thighs.
    Nausea and vomiting (sometimes).
    Diarrhea (occasionally).
    Sweating.
    Lack of energy.
    Urinary frequency.
    Irritability, nervousness, depression. CAUSES
    Strong or prolonged contractions of the muscular wall of the uterus. These may be caused by concentration of prostaglandins (hormones manufactured by the body). Research shows that women with dysmenorrhea produce and excrete more prostaglandins than those who don’t have as much discomfort. Dilation of the cervix to allow passage of blood clots from the uterus to the vagina.

    54. Retroverted Uterus - Dysmenorrhea Treatment By Uterine Suspension
    dysmenorrhea uterine suspension can relieve dysmenorrhea ina significant number of women with a retroverted uterus.
    http://www.inletmedical.com/html/dysmenorrhea.htm
    Uterine Suspension and the Treatment of Dysmenorrhea Related to a Retroverted Uterus Background Uterine retroversion has been considered an anatomic variant that is largely asymptomatic. However, some of the 20 to 30% of women with a retroverted uterus experience a constellation of chronic pelvic pain symptoms including severe dysmenorrhea. When dysmenorrhea is refractory to medical therapy, possible contributing factors should be carefully considered in the process of developing a treatment plan. These factors include endometriosis, functional disorders of the urinary and gastrointestinal systems and/or pelvic floor defects. Diagnosis should include a detailed medical history and a thorough pelvic exam. Tests including laparoscopy may also identify possible causative factors. If uterine retroversion is the only documented pathology, uterine suspension should be considered as a conservative therapy in women experiencing chronic pelvic pain including dysmenorrhea. Newer laparoscopic uterine suspension techniques and careful patient selection make it possible to obtain good long-term relief of dysmenorrhea with minimal procedure and recovery time.

    55. DYSMENORRHEA
    The summary for this Japanese page contains characters that cannot be correctly displayed in this language/character set.
    http://www.ne.jp/asahi/clinic/yfc/pain.html
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    56. Dysmenorrhea: When Periods Are Painful
    Discusses primary and secondary dysmenorrhea, diagnosis, and factorsthat contribute to severe menstrual pain. Secondary dysmenorrhea
    http://www.menstrual-disorders.com/html/dysmenorrhea.php3
    Dysmenorrhea: When Periods are Painful
    No one really knows what causes menstrual pain, also called dysmenorrhea
    One theory is that menstrual cramps are caused when hormone-like prostaglandins are secreted and stimulate strong muscle contractions in the uterus. However, this theory has not been proven. Caffeine appears to increase menstrual pain as well as PMS symptoms, and different types of stress may also make it worse.
    About half of all menstruating women suffer from this condition, characterized by a dull or throbbing ache in the area of the uterus. Sometimes a woman may also experience a headache, nausea or lower back pain.
    Cramping that goes away after a few days and is not related to other physical problems is called primary dysmenorrhea , which typically begins within a year or two of menarche. When cramps are intense and due to an underlying abnormality, they're called secondary dysmenorrhea , which can occur years after a woman has begun to menstruate.
    Vomiting, diarrhea, sweating or dizziness may accompany primary or secondary dysmenorrhea. In fact, it can feel just like the flu!
    Seeing a doctor is important if menstrual pain is so severe that it interferes with a woman's normal activities.

    57. National Guideline Clearinghouse - RECOMMENDATIONS FOR THE TREATMENT OF DYSMENOR
    All Rights Reserved. RECOMMENDATIONS FOR THE TREATMENT OF dysmenorrhea. Incidencedysmenorrhea is the most common gynecologic problem in menstruating women.
    http://www.guideline.gov/guidelines/ngc_1963.html
    RECOMMENDATIONS FOR THE TREATMENT OF DYSMENORRHEA INTRODUCTION:
    • Definition: Dysmenorrhea: Greek for painful menstruation, and often described as cramping, lower abdominal pain with or without backache that occurs just prior to and/or during menses.
    • Primary Dysmenorrhea: Menstrual pain without pelvic pathology occurring with ovulatory menstrual cycles Secondary Dysmenorrhea: Menstrual pain associated with pelvic pathology Incidence: Dysmenorrhea is the most common gynecologic problem in menstruating women.
    • Primary Dysmenorrhea:
        50% of menstruating women experience dysmenorrhea 10% of menstruating women are incapacitated for 1-3 days/month, leading to absence from school or work. Some evidence shows that there is an increased incidence or occurrence of more severe episodes of dysmenorrhea in women who are obese, smoke, are nulliparous or delay childbearing, or are sexually inactive. Onset occurs when ovulatory cycles begin, usually 6-12 months after menarche, peaks during the late teens and early 20’s, then declines gradually with age.
      Secondary Dysmenorrhea:
        Exact incidence is unknown due to its many causes.

    58. Gyneclogy Research - Dysmenorrhea (mentrual Cramps)
    Women’s Center for MindBody Health. Gynecology Research (dysmenorrhea). Home.New. The Center. dysmenorrhea (Menstrual Cramps). Psychology. Physiology. Treatment.
    http://womensmindbodyhealth.info/dysmenorrhea528.htm
    Women’s Center for Mind-Body Health Gynecology Research (Dysmenorrhea) Home New The Center M-B Health ... Gynecology Obstetrics Stress Physiology M-B Methods Sleep Cancer Children Other spec. The focus of this research database is on how stress affects women's health, and options for treatment using mind-body therapies. If you are not a health care professional, see new "Medical Glossary" below. To obtain full summaries of the articles, see "How to Get Abstracts" below. General PMS Birth Control Dr. - Patient ... ** How to Get Abstracts ** Dysmenorrhea (Menstrual Cramps) Psychology Physiology Treatment Psychology JA Factors influencing the prevalence and severity of dysmenorrhoea in young women In a group of Swedish women followed longitudinally, dysmenorrhea at age 24 was significantly less than at age 19. At 24, 67% reported cramping, 10% significant enough to limit daily activity. Reduction in prevalence and severity of dysmenorrhea was associated with women who had had children and those on birth control pills. 1990 Br J Obstet Gynaecol 97;7:588-94

    59. Cramps Really Are Cramps (Dysmenorrhea)
    Treatment of dysmenorrhea by Vaginal EMG Biofeedback. Instead of researching'sex', we'll research 'dysmenorrhea' today , I replied.
    http://www.incontinet.com/dysmenorrhea.htm
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    "Cramps" really are "cramps"!
    O ften the most significant discoveries are serendipitous, and the present case study is a prime example. The subject was a 21-year-old college student who wanted to earn $25 by participating in basic "Masters and Johnson" type sex research. But on the appointed Saturday morning she appeared at the laboratory with a tortured look on her face. "I really want to do this, and I really need the money," she exclaimed, "but I just got my period this morning and I am in absolute agony with cramps. What can I do?" It did not take long to come up with an answer. "Instead of researching 'sex', we'll research 'dysmenorrhea' today", I replied. It is actually a rare opportunity to get research subjects when they are in great pain they usually call up and cancel. Insertion of the vaginal EMG sensor required removal of her tampon, with predictable consequences. But replacement of the bed sheets and blanket was a small price to pay for the valuable data we collected that day.

    60. Chiropractic And Dysmenorrhea
    Response to dysmenorrhea Study Published in Pain From Anthony L. Rosner,Ph.D., FCER Director of Research. Des Moines, IowaPatricia
    http://www.fcer.org/html/news/dysmenorrhea.htm
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    For Release: May 1, 1999

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    Response to Dysmenorrhea Study Published in Pain
    From Anthony L. Rosner, Ph.D., FCER Director of Research Des Moines, Iowa
    -Patricia Brennan's dysmenorrhea study, a full-scale clinical trial begun in 1992, has resulted in a paper accepted for publication in April 1999 by the journal Pain It was preceded by a pilot study addressed to the same issue which was published in the Journal of Manipulative and Physiological Therapeutics in 1992 . Unfortunately, the recent publication in Pain suffers from a number of design flaws, omissions of data, and unexplained contradictions with the earlier pilot studyall of which significantly compromise its validity and leave more questions unanswered than resolved. One wishes that greater efforts were made by the authors to resolve what had appeared to be a positive result in the earlier investigation with the negative findings obtained in the more recent publication, above and beyond what sometimes might be expected with the differences of population types and numbers between the two investigations.
    The purpose in both of these studies was to assess the comparative effects of a high force spinal manipulative therapy (SMT) and low force maneuver (LFM) in affecting the pain and prostaglandin levels experienced in women with primary dysmenorrhea. The full-scale trial employed patient groups of 65-70, approximately three times larger than those employed in the pilot study. In addition, it observed patients over a total of four menstrual cycles: one as a baseline control after which subjects were randomized into the two intervention groups, and

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