61. University Of Iowa Family Practice Handbook A detailed description of emphysema and chronic bronchitis. http://indy.radiology.uiowa.edu/Providers/ClinRef/FPHandbook/Chapter03/04-3.html

62. Protein Crucial For Elastic Fiber Developement Described By UCSD Schol Of Medici fiber in the body. In addition, this loss can lead to some forms ofchronic lung disease, such as emphysema. Now, new findings by http://health.ucsd.edu/news/2002/01_09_Nakamura.html

Embargoed by Nature for 2 p.m. EST Wednesday, January 9, 2002 Protein Crucial for Elastic Fiber Development Described by UCSD School of Medicine Researchers Sagging skin and stiff, twisted arteries are considered a natural, if unfortunate, aspect of growing old that is caused by loss of elastic fiber in the body. In addition, this loss can lead to some forms of chronic lung disease, such as emphysema. Now, new findings by researchers at the University of California, San Diego (UCSD) School of Medicine offer insight into the role of a recently discovered protein in the development of elastic fibers, and the potential for future therapies to combat these and other aspects of aging. In a paper published in the January 10, 2002 issue of the journal Nature , investigators in the UCSD Institute of Molecular Medicine (IMM) describe the crucial role of a protein called fibulin-5, or DANCE (Developing Arteries and Neural Crest EGF-like), in the generation and organization of elastic fibers in mice. Tomoyuki Nakamura, M.D., Ph.D.

63. This Week's Program Statistics don't tell the whole story of tobacco disease and death. That's why PBS is running a program on Pam Laffin, a woman who tells her own story of emphysema caused by tobacco products. The story of how she got started smoking, how she discovered she had the disease, and how she lives her live now with one lung, is more compelling sometimes than any amount of statistics. http://www.pbs.org/healthweek/featurep3a_320.htm

Resources: American Cancer Society Web site If you want to contact Pam you can do so at Pamlaf fin@aol.com Massachusetts Dept. of Public Health Smoking's Deadly Effects Books are a good way to learn. But they often fall short when it comes to teaching children the dangers of smoking. And that's why a 29-year-old woman named Pam Laffin is heading out to Massachusetts schools and appearing in TV ads, to share her moving story of smoking's deadly effects. PAM LAFFIN: "I've lost so many things to this disease. I can't play with my kids. I can't go bike riding. I can't enjoy a walk on the beach. I thought I was the only person in the world that was young with emphysema, and when I found out that that wasn't the case, I thought maybe I should warn people." "I started smoking when I was ten. Did you ever see the movie Grease? I made my mother take me to get a perm to I could have curly hair like Sandy. It seemed like to me that most of the people in her new school didn't accept her, and she started smoking, and then she was friends with everybody. So I thought maybe if I smoked I could be like her." "I ran track, I was active and healthy. I figured that nothing bad was going to happen to me. When I was 21, I started getting bronchitis a lot. Over the next couple of years, my breathing got worse and worse. Until I couldn't like walk across the street to get the bus, if I walked up the stairs to get into my apartment, it took me 20 minutes to catch my breath."

64. Learn About Emphysema From Plainsense emphysema, a type of Chronic Obstructive Pulmonary Disease (COPD), is a chronic,irreversible but preventable disease. UNDERSTANDING emphysema. http://www.plainsense.com/Health/Seniors/emphysema.htm

Search the Web. Type it and go! Related Topics: Anemia Angina Arthritis Breast Cancer ... Elderly Abuse Emphysema Fitness Flu Foot Problems Future ... Weight Control UNDERSTANDING EMPHYSEMA Emphysema, a type of Chronic Obstructive Pulmonary Disease (COPD), is a chronic, irreversible but preventable disease. It occurs when the tiny air sacs (alveoli) of the lungs are damaged and lose their elasticity. The bronchial tubes become swollen and inflamed and the lungs begin to deflate or spring shut. Emphysema develops gradually over years. The majority of people who have this disease are, or were, smokers. The first symptom of emphysema is usually shortness of breath during exertion. As the disease progresses, the shortness of breath increases and even speaking more than a few words at a time can be difficult. Low oxygen levels, due to the lungs inability to absorb oxygen, can turn lips and fingers blue. The heart becomes burdened trying to maintain circulation, and heart failure is a common result. Each year more than 50,000 people die or are handicapped from emphysema. Unfortunately, emphysema can't be cured, but there are treatments available to help slow the progression of the disease. HOW TO REDUCE YOUR RISK If you smoke, quit now; if you don't, never start.

65. Member Sign In Cor Pulmonale With emphysema from Ventricular Electrocardiography J. Willis Hurst,MD. Introduction. Am J Cardiol 16503, 1965.). Cor Pulmonale With emphysema. http://www.medscape.com/viewarticle/404385

If you are having trouble logging in: In order to use Medscape, your browser must be set to accept "cookies." To find out how to adjust your browser settings, please click here Log In Username Password Forgot your password? Not a Member? Register Now for free access to: MEDLINE (Optimized for Physicians) 200+ Free CME Courses 25 Medical Specialty Sites 100+ Medical Journals Conference Coverage Daily Medical News About Medscape Help WebMD Health

66. Family Of COPD Support Lists And Programs emphysema can best be characterized as the progressive destruction of the grapelikesacs that fulfill the lung's basic function exchanging oxygen in the air http://copd-support.org/

You can be upset because rosebushes have thorns Or you can rejoice because thorn bushes have roses. Author Unknown About Us Caregivers Chatroom Chatroom Schedule ... Watch Program Welcome The List uses LSoft and other methods to distribute e-mail to subscribers of the family of COPD Lists. Presently there are over 2,000 subscribers world wide representing a number of countries and cultures. Frequently referred to as "The List", there really is no single list. Rather, there are a number of lists and programs intended to help meet the needs of individuals afflicted with COPD, caregivers who are responsible for an individual so afflicted, and medical personnel who have a particular interest in pulmonary medicine in general and COPD in particular. Purpose The List was established to provide support and education, and as a forum for sharing ideas and solutions in dealing with this affliction. Subscribers are encouraged to participate in the discussion, though they are entitled to just "lurk" if they so choose. The List, and thus this web page, was established to bring together people affected by COPD. It is here to help us communicate with one another; to share ideas and knowledge; to support one another; and to live longer, better quality lives. About COPD Chronic Obstructive Pulmonary Disease, or COPD, is a disease that encompasses one or more of the following:

67. Easy Rider Ain't So Easy. A Living With COPD Story By Pat Dooley I am a 50 year old man, diagnosed with COPD severe emphysema, chronic bronchitis and a moderate asthmatic component. I started smoking when I was about 14 years old http://www.papapoo.com/copd-pat.html

Pat Dooley in his country setting Easy Rider Ain't So Easy Pat Dooley and His Lady Pat Dooley September 1999 Write Pat an E-Mail Personal Stories Table of Contents

68. The Emphysema File: Promising Emphysema Research Current therapies for emphysema and chronic obstructive pulmonary disease (COPD),including surgical options, drug treatments in emphysema care, oxygen and http://www.lifestages.com/health/emphysem.html

The Emphysema/COPD File SM C E N T E R F O R C U R R E N T R E S E A R C H Approved by Physicians' Home Page Medinex Seal of Approval WellnessWeb: The Patient's Network HONcode Principles of the Health On the Net Foundation Partners of CareData.com W Emphysema/COPD File . Learn about late-breaking research from recognized experts at pulmonary clinics and lung disease centers worldwide. Compiled from the National Medical Library database at the National Institutes of Health, the Emphysema/COPD File Emphysema/COPD File surgical options-including video-assisted thoracoscopy (VATS), no-cut thoracoscopic lung plication, sternotomy, laser ablation of pulmonary bullae, and lung transplantation for end-stage emphysema and much more. It's all in the Emphysema/COPD File , and it's all organized and ready for you to download now.

69. THE OVERHOLT-BLUE CROSS EMPHYSEMA SURGERY TRIAL (0BEST) A multicenter randomized clinical trial on lung volume reduction surgery. http://www.ctsnet.org/doc/2375

THE OVERHOLT-BLUE CROSS EMPHYSEMA SURGERY TRIAL (0BEST); A MULTICENTER RANDOMIZED CLINICAL TRIAL ON LUNG VOLUME REDUCTION SURGERY A. SPONSOR Blue Cross Blue Shield of Massachusetts (Tel. No. 1 800 214 0019) B. PARTICIPATING HEALTH PLAN Blue Cross Blue Shield of Massachusetts Harvard Pilgrim Health Plan Others: being negotiated C. SUPPORTERS U.S. Surgical Corp., BioVascular Co. GlaxoWellcome and The Thoracic Foundation granted the funds for the research component of OBEST. D. PARTICIPATING CLINICAL SITES Medical-Surgical Centers. Medical-Surgical Centers are designated to perform all screening and diagnostic procedures, pulmonary rehabilitation, LVRS, and follow-up studies. Medical-Surgical Center Telephone Number Beth Israel-Deaconess Medical Center, Boston Brigham and Women's Hospital, Boston 1 888 BWH LUNG Lahey-Hitchcock Clinic, Burlington Massachusetts General Hospital, Boston U. Mass-Memorial Hospitals, Worcester Satellite Consortium Centers. The Satellite Consortium Centers are designated to provide all screening and diagnostic procedures, pulmonary rehabilitation and follow-up studies but will not perform LVRS. It is anticipated that by participating in the activities of OBEST, the Consortium Center staff will gain sufficient expertise to perform LVRS independently and set up second generation OBEST Medical Surgical Centers, if and when the demand for LVRS increases. The following hospitals were selected as Satellite Consortium Centers: Satellite Consortium Center Telephone Number Bay State Medical Center, Springfield

70. Local & State: Red Tide Means 'Emphysema Beach' For Some Red tide means 'emphysema Beach' for some. But most vacationers persevere. By KEVINLOLLAR, klollar@newspress.com and BETSY CLAYTON, bclayton@news-press.com. http://www.news-press.com/news/local_state/030318redtideupdate.html

var USATAffilCode= 'fm'; [an error occurred while processing this directive] Cape Coral Bonita Springs Lehigh Education ... Home Delivery Red tide means 'Emphysema Beach' for some But most vacationers persevere By KEVIN LOLLAR, klollar@news-press.com and BETSY CLAYTON, bclayton@news-press.com The familiar screech of gulls on area beaches was drowned out Tuesday by the hacking, coughing, wheezing and sneezing of humans under the influence of red tide. Despite dead fish, stench, and respiratory irritation, people insisted on doing the Southwest Florida beach thing. HOW TO HELP Mote Marine Laboratory is beginning research to determine how far inland people feel the effects of red tide, which include coughing, sneezing and itchy eyes. If you feel red tide symptoms away from the beach, email bkirkpat@mote.org You may remain anonymous, but please give the address of where you felt symptoms. “It’s not keeping people away, but it’s like Emphysema Beach down here,” said Brian Palumbo, who works at West Coast Surf Shop on Fort Myers Beach. “Everybody’s coughing, but they’re on vacation, so they’re going to come no matter what.” Visitors on Sanibel also endured the stink and irritation.

71. PersonalMD.com - Your Lifeline Online Over 700 health topics for COPD and emphysema patients. http://www.personalmd.com/pulmonarycenter.shtml

Home Noticias de Salud Family Centers Health Centers ... My Health Manager Search PersonalMD Services Family Health Women's Health Children's Health ... Health Encyclopedia Pulmonary Center In the Spotlight Health Topics for you Over 700+ Topics Asthma COPD Emphysema Lung Cancer Pneumonia Quit Smoking Tuberculosis Is Your School Asthma-Friendly? Asthma Statistics Smog-Related Health Problems The term smog is generally used to mean chemical air pollution. The word is a combination of the words "smoke" and "fog." Smog primarily comes from the combustion of fossil fuels. A common example is car exhaust, which comes from the combustion of gasoline More Features So, What's Sarcoidosis? Sarcoidosis is a multi-organ system disease with no known cause. It commonly affects the lungs, skin, eye and lymph nodes where the abnormal tissue development is seen in multiple areas... More Patches, Pills And Gum: The Uphill Battle Against Cigarette Smoking (Part 2)

72. Emphysema NORTH SHORE LONG ISLAND JEWISH HEALTH SYSTEM emphysema TREATMENT TRIAL PROGRAMS. emphysemais a devastating disease caused by destruction of lung tissue. http://www.lij.edu/lijh/pulmonary/emphysema.html

NORTH SHORE - LONG ISLAND JEWISH HEALTH SYSTEM EMPHYSEMA TREATMENT TRIAL PROGRAMS Emphysema - an Introduction E mphysema is a devastating disease caused by destruction of lung tissue. The usual cause is cigarette smoking. As tissue is destroyed in the lung, large airspaces or holes appear in the lung. The elastic properties of the lung are decreased and the airways narrow. This results in overinflation of the lung (lungs too large), large decreases in the patient's ability to move air in and out of the lungs, and decreases in the ability of oxygen to pass into the blood from the lungs. Emphysema, when severe, is as devastating and debilitating as cancer, severe heart failure or any other severe chronic disease. The most troublesome symptom is severe shortness of breath of even the most trivial effort. Patients may develop a whole host of secondary symptoms such as anxiety and depression, severe pulmonary infections, heart failure, and respiratory failure. Mortality is considerably increased in emphysema patients. Traditional Treatment T raditional medical treatment consists of smoking cessation (the first step), medications to open the airways of the lungs as much as possible (bronchodilators), medications to decrease inflammation in the airways (steroids), oxygen, and antibiotics for pulmonary infections. Inhalers for the administration of bronchodilators and steroids are frequently used.

73. Pleaselisten I am 11 years old and my mother has emphysema from smoking. Please listen to me what it's like to have a sick Mom . A story about tobacco victims who don't smoke. http://www.geocities.com/Heartland/Valley/6578/kidsbutthead_.htm

Please Listen To Me by Katlyn This is Mom (Sharon) and me. When this picture was taken she had pneumonia. She is taking her nebulizer in this picture. It helps to clear her lungs so she can breathe better. This is her now with oxygen and she only weighs 87 lbs. A journal written by Katlyn when she was 10 years old which continues on thoughout her teen years. I want to tell you how I feel about my mom being sick.Because maybe you will know how bad lung disease is and it all starts with smoking mostly. I am Katlyn Adkins and I’m 10 and I already lost my father and now my mom is sick. She gets colds from me and I feel real bad but its not my fault because she gets colds from anyone even at the store. My mom has lung disease and she can’t do things like she used to.I have a lot of chores to do now but mom does’nt make me do them but I do them because I dont want her to.She is tired very much all the time and coughs a lot.She had to go to the hospital a few times to.It is scary when your mom is in the hospital and you cant be there to and I always think she will die.She said she cant tell me how long she will live but she wants to see my kids

74. Diseases And Conditions -- Discovery Health -- Emphysema emphysema is a type of chronic obstructive airway disease, or COPD. emphysemainvolves the gradual destruction of alveoli in the lungs. http://health.discovery.com/diseasesandcond/encyclopedia/775.html

emphysema By William M. Boggs, MD Images (click to view larger image) Emphysema is a type of chronic obstructive airway disease , or COPD. People with COPD have limitations in the flow of air through their airways. Emphysema involves the gradual destruction of alveoli in the lungs. The alveoli are air spaces where oxygen is exchanged with carbon dioxide in the blood. What is going on in the body? The most common cause of emphysema is smoking . Long-term exposure to smoke causes destruction of the alveoli. The ability of the lungs to provide oxygen to the body decreases. As a result, the person finds it increasingly difficult to breathe and to exercise without discomfort. The World Health Organization, or WHO, has recently developed a classification system for the severity of emphysema and other forms of COPD. There are four stages of severity, as outlined below: Stage 0, or at risk for COPD. These people have chronic cough and sputum production. Their lung function tests are still normal. Stage I, or mild COPD. Individuals in this group have mild limitations in their airflow and changes in their lung function tests . They generally have chronic cough and sputum production. Stage II, or moderate COPD. People at this stage have worsening of airflow that leads to

75. Emphysema And Bronchitis Research - Lovelace Respiratory Research Institute emphysema and Bronchitis Research. The Lovelace Respiratory to emphysemaresearch. We have several animal models of emphysema and bronchitis. http://www.lrri.org/kc/PofD/e&br.html

Key Capabilities BSL-3 Facilities Preclinical Safety and Efficacy Therapeutics ... Managed Care Database Pathobiology of Disease Emphysema and Bronchitis Research Lung Immunology and Asthma Lung Cancer Cell Biology Toxicology and Human Health Risks ... Human Research Capabilities Emphysema and Bronchitis Research The Lovelace Respiratory Research Institute offers expertise in pulmonary pathology, biochemistry, cell biology, animal models, and aerosol science that is important to emphysema research. We have several animal models of emphysema and bronchitis. Our capabilities and models provide opportunities for companies developing new pharmaceuticals, both in the development and preclinical trial phases. KEY CAPABILITIES: Animal Models of Emphysema Cigarette smoke-induced emphysema in mice Cigarette smoke-induced pulmonary inflammation and increased proteinases/elastases in mice prior to development of emphysema Multiple murine models assessed Elastase-induced emphysema in rats Animal Models of Bronchitis or Mucus Cell Hyperplasia SO2-induced bronchitis in dogs Endotoxin-induced rhinitis, bronchitis/bronchiolitis and mucus cell hyperplasia in rodents

76. LRRI's Approach To Emphysema / COPD LRRI's Approach to emphysema / COPD The Institute has numerous programsdesigned to create new treatments for COPD/emphysema. Previously http://www.lrri.org/cr/emphycopd.html

Current Research Maternal Influence in the Development of Asthma COPD: Research Creates New Optimism AZT Treatment for Pregnant Women Puts Kids at Risk ... LRRI Beagles Advance Alzheimer's Research LRRI's Approach to Emphysema / COPD Links Between Biomarkers and Cancer Center for Pharmacoeconomic and Outcomes Research Cell Death May Save Lives Identifying Markers for Lung Cancer and Genes for Therapy ... Research Archives LRRI's Approach to Emphysema / COPD The Institute has numerous programs designed to create new treatments for COPD/Emphysema. Previously thought to be intractable in terms of a cure or effective treatment or even cessation of disease progression, LRRI scientists believe that an effective treatment to stop progression and improve respiratory function and perhaps even cure Emphysema/COPD is possible and reachable in their lifetimes. We are currently investigating the following experimental research protocols:

77. Tobacco Facts And Cancer, Smoking, Larynx Cancer And Quitting The facts on tobacco products and cancer of the larynx, lung, and mouth, emphysema, epidemology, and how to quit; information and graphic pictures from a Kentucky physician. http://www.tobacco-facts.info

by Kevin T. Kavanagh, MD www.entusa.com Tobacco use and smoking are very dangerous addictions which commonly cause a wide variety of diseases, cancer and death. The vast majority of tobacco users and smokers are hooked when they are children. During this time period they are easily influenced by peer pressure and advertising. Once hooked, the majority of tobacco users become hopelessly addicted. More than 5 million children living today will die prematurely because of a decision they will make as adolescents-the decision to use tobacco and smoke cigarettes. Studies indicate that nonsmokers are also adversely affected by environmental tobacco smoke. There are 4000 chemicals in tobacco with 100 identified poisons and 63 known drugs which cause cancer. The most talked about drug in tobacco is nicotine. Nicotine is vasoconstrictor and a nerve toxin, it has been classified as a class I insecticide. Other poisons include: Arsenic, Cyanide, Formaldehyde (used to embalm bodies), Ammonia Bromide (a toilet cleaner )- Ref. 1. Each year, because of exposure to environmental tobacco smoke, an estimated 3,000 nonsmoking Americans die of lung cancer, and 300,000 children suffer from lower respiratory tract infections.

78. Bronchitis And Emphysema - Health Canada Tobacco Control Programme Bronchitis and emphysema. Chronic bronchitis and emphysema are two commonlung diseases specifically associated with smoking. What is emphysema? http://www.hc-sc.gc.ca/hecs-sesc/tobacco/facts/health_facts/bronchitis.html

Bronchitis and Emphysema Chronic bronchitis and emphysema are two common lung diseases specifically associated with smoking. What is Chronic Bronchitis? Chronic bronchitis is the production of excess mucus in our lungs and causes problems in absorbing oxygen. The excess mucus impairs breathing and is usually associated with constant coughing, which is a natural mechanism that removes foreign particles and irritants from our lungs. Healthy lungs have a natural cleaning process that removes the dust and smoke and other foreign particles that are part of the air, allowing us to breathe normally. Tobacco smoke contains many harmful chemicals, and the smoke itself limits our lungs' natural filtering/cleaning system. Cigarette smoke also contains substances that directly damage the lung tissue Smoking irritates the bronchial tubes in the lungs which in turn results in the production of more mucus. Smokers' cough, as it is commonly known, is a sign that the lungs are trying to clean themselves. Long-term exposure to cigarette smoke destroys the structure of our lungs, reducing their capacity to absorb oxygen. At the same time, the tiny airways which transfer oxygen from the lungs to the blood vessels are destroyed, resulting in less oxygen getting into the bloodstream

79. Lung Volume Reduction Surgery For The Treatment Of Severe Emphysema An article from Harrison Online written by Robert M. Rogers, MD. http://respiratorycare.medscape.com/33213.rhtml?srcmp=rc-020201

80. Congenital Lobar Emphysema, Cincinnati Childrens Hospital Medical Center Information on congenital lobar emphysema including symptoms, diagnosis andtreatment, provided by Cincinnati Children's Hospital Medical Center. http://www.cincinnatichildrens.org/Health_Topics/Your_Childs_Health/chest_and_lu

Your Child's Health Chest and Lungs Conditions and Diagnoses Overview ... Congenital Diaphragmatic Hernias and Other Related Diaphragmatic Anomalies Congenital Lobar Emphysema Croup Understanding Croup Cystic Fibrosis Diagnosis Influenza ... Tests and Procedures Conditions and Diagnoses Congenital Lobar Emphysema What is congenital lobar emphysema (CLE)? Congenital lobar emphysema is an uncommon respiratory disease seen primarily in newborns and young infants, and occurring more frequently in males. Small alveoli (air sacs in the lungs) that are partially blocked cause overinflation (overexpansion) of the affected section of the lung, which results in a decrease in respiratory function. Each person has a right and left lung; the right lung is divided into three sections called lobes, while the left lung is divided into two lobes. CLE usually affects only one lobe, and this is generally an upper lobe. It only rarely involves the lower lobes. Overinflation of the affected lobe can also cause compression of the normal lung on the opposite side of the chest, further compromising respiratory function. While there is no single clearly defined cause of CLE, several possible mechanisms are likely to be involved. These include a developmental abnormality of the small airways or alveoli, or structural abnormalities of the large airways. Though CLE can be a life-threatening condition, the results with early and appropriate intervention are good. What are the symptoms?

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