1. Epstein-Barr Virus Fact sheet from the Centers for Disease Control.Category Health Conditions and Diseases Viral epstein-barr virus......National Center for Infectious Diseases epsteinbarr virus and InfectiousMononucleosis, DISEASE INFORMATION. epstein-barr virus, frequently http://www.cdc.gov/ncidod/diseases/ebv.htm

National Center for Infectious Diseases Epstein-Barr Virus and Infectious Mononucleosis DISEASE INFORMATION Epstein-Barr virus, frequently referred to as EBV, is a member of the herpesvirus family and one of the most common human viruses. The virus occurs worldwide, and most people become infected with EBV sometime during their lives. In the United States, as many as 95% of adults between 35 and 40 years of age have been infected. Infants become susceptible to EBV as soon as maternal antibody protection (present at birth) disappears. Many children become infected with EBV, and these infections usually cause no symptoms or are indistinguishable from the other mild, brief illnesses of childhood. In the United States and in other developed countries, many persons are not infected with EBV in their childhood years. When infection with EBV occurs during adolescence or young adulthood, it causes infectious mononucleosis 35% to 50% of the time. Symptoms of infectious mononucleosis are fever, sore throat, and swollen lymph glands. Sometimes, a swollen spleen or liver involvement may develop. Heart problems or involvement of the central nervous system occurs only rarely, and infectious mononucleosis is almost never fatal. There are no known associations between active EBV infection and problems during pregnancy, such as miscarriages or birth defects. Although the symptoms of infectious mononucleosis

2. Epstein-Barr Virus-Key Text Kissing the epsteinbarr virus goodbye? Published by http://www.science.org.au/nova/026/026key.htm

Key text Kissing the Epstein-Barr virus goodbye? Published by Australian Academy of Science Sponsored by Glandular fever, a common disease in teenagers, is caused by the Epstein-Barr virus. Australian research on the Epstein-Barr virus has led to a glandular fever vaccine, which is currently being trialled. You will get more from this topic if you have mastered the basics of the immune system Printer-friendly version of complete topic Like most good things in life, kissing can be hazardous to your health. Pucker up to someone and you risk infection with the Epstein-Barr virus, which causes glandular fever and other nasty diseases. But we might not have to give up kissing just yet. A vaccine currently under development in Australian laboratories could help limit the dangers posed by this sometimes deadly virus. How was the virus discovered? In 1961, a surgeon working in Uganda, Denis Burkitt, presented the results of his research to staff at the Middlesex Hospital Medical School in Britain. He reported that the incidence of a certain tumour in African children had a geographic distribution corresponding to rainfall and temperature patterns. The disease, which affects about 8 in every 100,000 children in parts of Africa and Papua New Guinea, quickly became known as Burkitt’s lymphoma. The influence of climate on its incidence seemed to suggest that some biological factor was involved. Three researchers, M.A. Epstein, Y.M. Barr and B.G. Achong, immediately began looking for possible cancer-causing viruses in samples of the tumour sent from Uganda to Britain.

3. Epstein Barr Virus A brief description of this condition, and its causes, risks, life style changes, diet changes and Category Health Conditions and Diseases Viral epstein-barr virus......Home Library Health Concerns epsteinbarr virus epstein-barr virus. ChronicFatigue Syndrome (CFS), Immune Dysfunction Syndrome (IDS), epstein-barr virus. http://www.health4her.com/library/concerns/epstein_barr_virus.cfm

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4. Epstein-Barr Virus - A Teenage Girl's Story To Offer Support To Others Offers a message board for visitors to communicate with others who also suffer with this disease .Category Health Conditions and Diseases Viral epstein-barr virus......Welcome to my site. This web site is for all who have been diagnosedwith epsteinbarr virus or Chronic Fatique Syndrome. Please http://www.epstein-barr-virus.com/

Welcome to my site. This web site is for all who have been diagnosed with Epstein-Barr Virus or Chronic Fatique Syndrome Please feel free to look around and participate in our message board. If you enjoy what you see here, please recommend our site to a friend. -Kelly

5. Epstein-Barr Virus epsteinbarr virus. epstein-barr virus (EBV), herpesvirus that is the major cause of infectious mononucleosis and is http://www.infoplease.com/ce6/sci/A0817520.html

Reduce your family medical costs by up to 60% now! Oral health..Save up to 60% on dental care. Easy Medical Diagnosis..stop smoking! All Infoplease All Almanacs General Entertainment Sports Biographies Dictionary Encyclopedia Infoplease Home Almanacs Atlas Dictionary ... Fact Monster Kids' reference Info:Daily Fun facts Homework Center Newsletter You've got info! Help Site Map Visit related sites from: Family Education Network Encyclopedia Epstein-Barr virus Epstein-Barr virus (EBV), herpesvirus that is the major cause of infectious mononucleosis and is associated with a number of cancers, particularly lymphomas in immunosuppressed persons, including persons with AIDS. Epstein-Barr is a ubiquitous virus, so common that it has been difficult to determine whether it is the cause of certain diseases or whether it is simply there as an artifact. In Third World nations, most children are infected with EBV; in most industrialized nations, about 50% of the people are infected. Research has found that all of the lymphomas associated with AIDS and most lymphomas in other immunocompromised persons are connected with latent EBV infection. EBV has been found in biopsy tissue of patients with Hodgkin's disease , breast cancer, and some smooth muscle tumors. EBV also was formerly suspected as the cause of

6. Chronic Fatigue Possibly Related To Epstein-Barr Virus -- Nevada Chronic Fatigue Possibly Related to epsteinbarr virus Nevada. Persisting illnessand fatigue in adults with evidence of epstein-barr virus infection. http://www.cdc.gov/epo/mmwr/preview/mmwrhtml/00000740.htm

May 30, 1986 / 35(21);350-2 Chronic Fatigue Possibly Related to Epstein-Barr Virus Nevada From November 1984 through August 1985, approximately 90 patients evaluated for persistent fatigue were diagnosed as having chronic Epstein-Barr virus (CEBV) disease by a two-physician community internal medicine practice near Lake Tahoe, Nevada. The diagnoses were made by detecting antibody to the diffuse (EA-D) or the restricted (EA-R) components of early antigen of EBV, as suggested by two recent studies (1,2). Because of controversy about whether CEBV disease exists, two serologic studies were conducted to evaluate whether a syndrome of chronic fatigue could be statistically associated with a specific pattern of antibody titers against EBV. Fifteen "case" patients, felt to be the most likely to have CEBV, were identified by interviewing 134 of the 139 patients tested for EBV serology in the internal medicine practice between January 1, and August 20, 1985. By definition, these patients had persistent or relapsing unexplained fatigue for at least 2 months, which forced them to stop usual daily activities for at least 2 weeks. Other less universal symptoms included intermittent low-grade fever, sore throat, myalgias, arthralgias, and headaches. All 15 patients were white; 13 were female. The median age was 40 years (range 13-52 years). In the first serologic study, the 15 patients were compared with 118 of the 119 patients who had serologic testing for EBV (the serologic test results on one patient were not available). All 118 of these patients were white; 79 (66.9%) were female. The median age was 36 years (range 10-71 years). The case patients were more likely to have reciprocal EA-D titers of 160 or higher (45.5%, compared with 11.6%; p = 0.014) and EBV viral capsid antigen IgG (VCA-IgG) 160 or greater (80.0%, compared with 51.7%; p = 0.033) in the first serum tested. No evidence of acute EBV infection, manifested by positive IgM titers to VCA, was detected in either the cases or the others tested.

7. Epstein Barr Virus-Useful Sites Mononucleosis (Mayo Clinic, USA). Infectious mononucleosis (also knownas glandular fever) is caused by the epsteinbarr virus. This http://www.science.org.au/nova/026/026sit.htm

Kissing the Eppstein-Barr virus goodbye? Useful sites Published by Australian Academy of Science Sponsored by Printer-friendly version of complete topic Viruses: a view from the textbooks (CSIRO Australia) Gives a good overview of viruses. It includes short sections on classification, detection, vaccines and the importance of mutation. The Ras gene and cancer (Access Excellence, USA) Describes how a class of virus contains an oncogene that causes the development of tumours in humans. A similar situation occurs in Burkitt's lymphoma, but with a different virus and different oncogene. http://www.accessexcellence.org/AB/BA/Ras_Gene_and_Cancer.html Mononucleosis (Mayo Clinic, USA) Infectious mononucleosis (also known as glandular fever) is caused by the Epstein-Barr virus. This clinical description includes symptoms, diagnosis and self-care. http://www.mayoclinic.com/findinformation/diseasesandconditions/invoke.cfm?id=DS00352 The following sites contain information about infectious mononucleosis and Burkitt's lymphoma: Epstein-Barr virus and infectious mononucleosis (Centers for Disease Control and Prevention, USA)

8. Epstein Barr Virus Antibodies From Research Diagnostics Inc epsteinbarr virus. epstein-barr virus (EBV), the cause of classic infectious mononucleosis, is an ubiquitous herpes http://www.researchd.com/viralab/trk3eb13.htm

rev: Apriil 2, 1999 HOME (RDI home page) Return (alphabetcial antibody page) RETURN (viral antibody list) A NTIBODIES (anti-Human and others as indicated) Research Diagnostics Inc offers a wide line of antibodies. Since no one antibody works best for all applications (neutralization, blotting, histochemistry, ELISA, etc), we offer many different types of antibodies to help solve this problem. Please inquire for other applications or types of antibodies not listed below. PRODUCT DATA SHEET Monoclonal mouse anti-Epstain Barr virus CAT#: RDI-TRK3EB12-2E3 or RDI-TRK3EB13-4C5 PRICE: $300.00/mg or $250.00/mg 2 or more Clone: 2E3, 4C5 These clones have been derived from hybridization of Ag8-653 myeloma cells with spleen cells of a Balb/c mice immunized with Epstain virus from the B-95-8. Specificity: p 160 virus capsid antigen for clone 2E3 gp 87 virus envelope antigen for clone 4C5 Reactivity: MoAb 2E3 reacts with purified EBV-viruses from P3HR-1 and B-95 infected cell lines in ELISA. MoAb 4C5 reacts with purified EBV virus in ELISA and inhibits hemagglutination of concentrated EBV.

9. Epstein-Barr Virus It's here for you and I to discuss what epsteinbarr virus is about, whatwe can do about it, and what struggles we face. Current Message Board. http://www.epstein-barr-virus.com/message_board.htm

Please feel free to participate in our on-line message board. It's here for you and I to discuss what Epstein-Barr Virus is about, what we can do about it, and what struggles we face. Current Message Board Previous Message Board -Kelly

10. Epstein-Barr Virus Help and Information on epsteinbarr virus epstein-barr virus. epstein-barr virus (EBV) is a condition that has become widespread in the USA. http://www.symmcorp.com/health/epstein-barr.htm

Epstein-Barr Virus Epstein-Barr virus (EBV) is a condition that has become widespread in the USA. The causes of epstein barr is not well understood. Some experts believe it is associated with chronic fatigue syndrome (CFS) based on the fact that many people with chronic fatigue syndrome have high level of EBV antibodies in their blood. Intestinal parasites are also common with people who have chronic fatigue syndrome. Epstein-Barr can reoccur at any time especially after illness or stress. Nutrient / Supplement Helpful notes Fatty Acids helps strengthen your body's immune system which is weaken by epstein-barr. Fatty acids are found in omega fatty acids from fish oil, flax seed oil, and borage seed oil. Acidophilus replaces needed bacteria that are helpful to your digestion and also helps fight infection. Sometimes found is a vitamin herbal mixture. Multi-vitamin contains vitamin E vitamin B vitamin C magnesium ... potassium , and zinc which all are helpful in both the treatment and prevention of epstein barr and chronic fatigue syndrome.

11. MedWebPlus Subject Diseases And Conditions Epstein-Barr Virus A, , GO, Centers for Disease Control and Prevention. National Center forInfectious Diseases. epstein-barr virus and Infectious Mononucleosis. http://www.medwebplus.com/subject/Diseases_and_Conditions/Epstein-Barr_Virus_Inf

Main About MWP Contribute to MWP Contact Us A service of Flexis, Inc. Welcome to MedWebPlus 2.3! A free service to help you find health sciences information quickly and easily. Diseases and Conditions Epstein-Barr Virus Infections Broader Terms: All Diseases Communicable Diseases Herpesviridae Infections Virus Diseases Related Terms: Animal Diseases Digestive System Diseases Eye Diseases Musculoskeletal Diseases ... Virus Diseases Narrower Terms: Infectious Mononucleosis Focussed Subsets: Infectious Mononucleosis Web Sites: A GO adam.com Encyclopedia Disease Reference Infectious mononucleosis (EB) (Iowa Clinic) A GO AIDS Knowledge Base Cytomegalovirus A GO Bristol Biomedical Image Archive Cytomegalovirus Infections A GO Centers for Disease Control and Prevention. National Center for Infectious Diseases. Cytomegalovirus (CMV) Infection A GO Centers for Disease Control and Prevention. National Center for Infectious Diseases. Epstein-Barr Virus and Infectious Mononucleosis A GO emedicine Neurology HIV-1 Associated Opportunistic Infections: Cytomegalovirus Encephalitis from Neurology/Neurological Infections / authored by Florian P. Thomas A GO Medical College of Wisconsin HealthLink Cytomegalovirus A GO National Prion Disease Pathology Surveillance Center A GO The Body Cytomegalovirus (CMV) A GO United Kingdom. Ministry of Health.

12. MedWebPlus Subject Epstein-Barr Virus Infections A free service to help you find health sciences information quickly and easily. EpsteinBarrVirus Infections epstein-barr virus and Infectious Mononucleosis. http://www.medwebplus.com/subject/Epstein-Barr_Virus_Infections

Main About MWP Contribute to MWP Contact Us A service of Flexis, Inc. Welcome to MedWebPlus 2.3! A free service to help you find health sciences information quickly and easily. Epstein-Barr Virus Infections Broader Terms: All Diseases Communicable Diseases Herpesviridae Infections Virus Diseases Related Terms: Animal Diseases Digestive System Diseases Eye Diseases Musculoskeletal Diseases ... Virus Diseases Narrower Terms: Infectious Mononucleosis Focussed Subsets: Infectious Mononucleosis Web Sites: A GO adam.com Encyclopedia Disease Reference Infectious mononucleosis (EB) (Iowa Clinic) A GO AIDS Knowledge Base Cytomegalovirus A GO AIDS Treatment Data Network Cytomegalovirus (CMV) A GO Bristol Biomedical Image Archive Cytomegalovirus Infections A GO Centers for Disease Control and Prevention. National Center for Infectious Diseases. Cytomegalovirus (CMV) Infection A GO Centers for Disease Control and Prevention. National Center for Infectious Diseases. Epstein-Barr Virus and Infectious Mononucleosis A GO emedicine Neurology HIV-1 Associated Opportunistic Infections: Cytomegalovirus Encephalitis from Neurology/Neurological Infections / authored by Florian P. Thomas A GO Medical College of Wisconsin HealthLink Cytomegalovirus A GO National Prion Disease Pathology Surveillance Center A GO The Body Cytomegalovirus (CMV) A GO United Kingdom. Ministry of Health.

13. Epstein-Barr Virus epsteinbarr virus and Infectious Mononucleosis. Original Source CENTERSFOR DISEASE CONTROL AND PREVENTION http//www.cdc.gov/ncidod http://www.sunflower.org/~cfsdays/Ebv.htm

Epstein-Barr Virus and Infectious Mononucleosis Original Source: CENTERS FOR DISEASE CONTROL AND PREVENTION: http://www.cdc.gov/ncidod/diseases/ebv.htm DISEASE INFORMATION Epstein-Barr virus, frequently referred to as EBV, is a member of the herpesvirus family and one of the most common human viruses. The virus occurs worldwide, and most people become infected with EBV sometime during their lives. In the United States, as many as 95% of adults between 35 and 40 years of age have been infected. Infants become susceptible to EBV as soon as maternal antibody protection (present at birth) disappears. Many children become infected with EBV, and these infections usually cause no symptoms or are indistinguishable from the other mild, brief illnesses of childhood. In the United States and in other developed countries, many persons are not infected with EBV in their childhood years. When infection with EBV occurs during adolescence or young adulthood, it causes infectious mononucleosis 35% to 50% of the time. Symptoms of infectious mononucleosis are fever, sore throat, and swollen lymph glands. Sometimes, a swollen spleen or liver involvement may develop. Heart problems or involvement of the central nervous system occurs only rarely, and infectious mononucleosis is almost never fatal. There are no known associations between active EBV infection and problems during pregnancy, such as miscarriages or birth defects. Although the symptoms of infectious mononucleosis

14. Multiple Sclerosis And Epstein-Barr Virus (EBV) 8/27/00 Calcium AEP, Progesteron Multiple Sclerosis and epsteinbarr virus. German researchers havedemonstrated that there may be an association between the Epstein http://www.mercola.com/2000/aug/27/multiple_sclerosis_epstein_barr.htm

Mercola.com Dr. Joseph Mercola All Health, No Hype FREE Weekly Health Newsletter Your Email Address: Previous Newsletters Issue 168 August 27, 2000 Estrogen Therapy Does Not Cut Heart Disease Diabetes Rates Skyrocketing and Starting Younger Sugar Produces Free Radicals Vitamin B12 Deficiency Widespread ... Understanding Adrenal Function Health Resources Complete Nutrition Plan Less Grains / Sugars More Omega 3 More Water ... Recommended Products Multiple Sclerosis and Epstein-Barr Virus German researchers have demonstrated that there may be an association between the Epstein-Barr Virus (EBV) reactivation and disease activity in Multiple Sclerosis (MS) patients over time. 108 MS patients and 163 controls were assessed for the prevalence of antibodies against herpes simplex virus type 1 (HSV-1), HSV-2, EBV, and cytomegalovirus (CMV). In contrast to the control populations, antibodies against EBV were present in 100% of MS patients.

15. Leeds Medical Information - Epstein-Barr Virus Report Some Information about epsteinbarr virus. Please note epstein-barr virus Reportis intended as a current awareness publication for clinicians and researchers. http://www.leeds.ac.uk/lmi/ebv/links.html

Epstein-Barr Virus Report Main Page Subscription Details Some Information about Epstein-Barr Virus Please note: Epstein-Barr Virus Report is intended as a current awareness publication for clinicians and researchers. LMI staff are not clinically trained, and as such are unable to answer questions about EBV diagnosis or diseases associated with it. We strongly recommend that your first point of contact for information regarding EBV should be your physician. The following information is provided for people concerned about EBV infection. It is not intended to be comprehensive, nor imply any commitment by LMI, or the University of Leeds. Web Links Mononucleosis Professor Robert S Wallis, Case Western Reserve University, USA Epstein-Barr Virus Professor Ray Baumann, University of Mississipi Medical Center, USA Chronic Fatigue Syndrome Homepage National Center for Infectious Diseases, Centers for Disease Control and Prevention, USA

16. Leeds Medical Information - Epstein-Barr Virus Report epsteinbarr virus Report. Journal of the International Associationfor Research on epstein-barr virus and Associated Diseases. Epstein http://www.leeds.ac.uk/lmi/ebv/ebvmain.html

Published by L eeds M edical ... Publications Epstein-Barr Virus Report Journal of the International Association for Research on Epstein-Barr Virus and Associated Diseases Editor in Chief Professor Lawrence Young Contents Introduction Editorial Board Subscription Details ... International Association for Research on EBV and Associated Diseases Page last updated 1st March 2002

17. QIMR Website - Epstein-Barr Virus Unit The epsteinbarr virus (EBV) Unit seeks to combine basic research with clinicalapplication to provide new strategies to treat human viral diseases. http://www.qimr.edu.au/research/units/ebv/

Unit Head: Professor Denis Moss EBV Biology Laboratory - Prof Denis Moss Molecular Vaccinology - Dr Andreas Suhrbier Experimental Immunology - Dr Ihor Misko Molecular Biology - Dr Tom Sculley Tumour Immunology - Dr Rajiv Khanna Diseases caused by viruses are one of the most important challenges facing medical research because unlike bacterial infections, antibiotics generally have little capacity to prevent virus replication. The Epstein-Barr virus (EBV) Unit seeks to combine basic research with clinical application to provide new strategies to treat human viral diseases. The Unit has a number of interlocking themes which include: The development of novel vaccine strategies with application to viruses and cancer. Determination of the mechanisms of immunity and pathogenesis to EBV, Ross River virus (RRV) and HIV. Defining the molecular events that lead to EBV establishing a life-long latent infection following first contact with the virus and the factors that subsequently cause cancers such as nasopharyngeal carcinoma (NPC), Burkitt’s lymphoma (BL) and post-transplant lymphoproliferative disease (PTLD). Successful vaccines rely on a full understanding of the immune mechanisms that protect from disease. The EBV Unit has been in the forefront of defining the components of the immune system that protect from EBV infection and how this protection fails in certain circumstances, resulting in cancer. All the evidence points to a major role for “killer” lymphocytes. These killer lymphocytes (referred to as cytotoxic T lymphocytes or CTL) recognise epitopes in association with proteins that cause transplantation rejection. This background has led us into the development of a procedure to treat heart and heart/lung graft recipients who are susceptible to EBV lymphomas which arise as a result of the use of immunosuppressive drugs.

18. QIMR Website - Epstein-Barr Virus Biology Laboratory epsteinbarr virus Biology Laboratory. Identification of type B-specific and cross-reactivecytotoxic T-lymphocyte responses to epstein-barr virus. J. Virol. http://www.qimr.edu.au/research/labs/denism/

Epstein-Barr Virus Biology Laboratory Labhead: Professor Denis Moss denisM@qimr.edu.au Staff Key Publications Go to ... Glossary Epstein-Barr virus (EBV) causes glandular fever and is associated with a number of cancers including lymphomas in transplant patients and a relatively common form of cancer in the back of the nose called nasopharyngeal carcinoma. The EBV Biology laboratory has a broad interest in all aspects of the biology of the virus and is closely linked with other laboratories within the Unit. Research Highlights: Definition of the components of the immune system that protect from EBV infection. In particular this laboratory has established the principle that "killer T cells" (CTL) are the main immune parameter responsible for controlling the long-term latent EBV infection that all immune individuals carry for life. Definition of immune parameters has led to the development of an EBV vaccine development program in association with CSL Ltd. Began treating patients with post-transplant proliferative disease (PTLD) with EBV immune cells grown in the test tube. Established the concept that the EBV immune response can recognise "self" antigens. This idea may have important consequences in relation to transplant rejection.

19. High Levels Of Epstein-Barr Virus Antibodies In Women Linked To Risk Of Multiple High levels of epsteinbarr virus antibodies in women linked to risk of multiplesclerosis Link between some type of infection and onset of MS has long been http://www.researchmatters.harvard.edu/story.php?article_id=346

20. Epstein-Barr Virus Causes Gastric Carcinoma epsteinbarr virus Causes Gastric Carcinoma. Although at negative. Epstein-Barrvirus is now implicated as the cause of many of these. The http://ourworld.compuserve.com/homepages/CarolASThompson/EBVgc.htm

Epstein-Barr Virus Causes Gastric Carcinoma Although at least 80% of stomach cancer is associated with Helicobacter pylori infection, there is a subset of cancers that are HP-negative. Epstein-Barr virus is now implicated as the cause of many of these. The proportion of cancers caused by each depends upon the proportion of each infection in various populations. Epstein-Barr virus-associated gastric carcinoma and Epstein-Barr virus infection of the stomach. M Fukayama, Y Hayashi, Y Iwasaki, J Chong, T Ooba, T Takizawa, M Koike, S Mizutani, M Miyaki, K Hirai. Lab Invest 1994 Jul;71(1):73-81. Fukayama / Lab Invest 1994 abstract Monoclonal Epstein-Barr virus genomes but lack of EBV-related protein expression in different types of gastric carcinoma. G Ott, T Kirchner, HK Muller-Hermelink. Histopathology 1994 Oct;25(4):323-329. Ott / Histopathology 1994 abstract In situ detection of Epstein-Barr virus in gastric and colorectal adenocarcinomas. St Yuen, LP Chung, SY Leung, IS Luk, SY Chan, J Ho. Am J Surg Pathol 1994 Nov;18(11):1158-1163. Yuen / Am J Surg Pathol 1994 abstract [Epstein-Barr associated gastric carcinoma: the genetic alteration and the expression of CD44 variant]. JM Chong, M Fukuyama. Nippon Rinsho 1997 Feb;55(2):381-385. "EBV-encoded small RNA was found in nearly all of the carcinoma cells even at the intramucosal stage."

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