1. The Erythromelalgia Association A non-profit organization dedicated to research and education regarding this painful disorder. Offers Category Health Conditions and Diseases erythromelalgia......Welcome To The erythromelalgia Association. What's New? March 2003 Newsletter FootSteps; Many new articles in the online library; New member passwords http://www.erythromelalgia.org/

Welcome To The Erythromelalgia Association What's New? March 2003 Newsletter - FootSteps Many new articles in the online library New member passwords... be sure to get yours! Use your VISA or MasterCard to donate, join, or renew your membership! The Erythromelalgia Association (TEA) is an international, all-volunteer organization serving patients, families, and friends. Erythromelalgia (EM) is a rare condition that can cause redness and pain in all parts of the body, but most frequently the feet and hands (extremities). It is characterized by intense, burning pain, severe redness (erythema), and increased skin temperature that may be episodic or almost continuous in nature. Although Erythromelalgia typically affects both sides of the body (bilateral), it may sometimes involve only one side (unilateral). In addition, the disease course may be extremely variable from case to case. For example, in some individuals, symptom onset may be gradual, with the condition potentially remaining relatively mild for years. However, in others, it may have a sudden onset, possibly spreading and becoming severe over weeks. The specific underlying cause of erythromelalgia remains unknown. However, the condition is thought to result from vasomotor abnormalities or dysfunction in the normal constriction and dilation of the diameter of certain blood vessels, leading to abnormalities of blood flow to the extremities. Erythromelalgia may be an isolated, primary condition or occur secondary to various underlying disorders.

2. THE MERCK MANUAL, Sec. 16, Ch. 212, Peripheral Vascular Disorders The cause of primary erythromelalgia is unknown. Secondary erythromelalgia may occur in patients who have http://www.merck.com/pubs/mmanual/section16/chapter212/212f.htm

This Publication Is Searchable The Merck Manual of Diagnosis and Therapy Section 16. Cardiovascular Disorders Chapter 212. Peripheral Vascular Disorders Topics [General] Peripheral Arterial Occlusion Thromboangiitis Obliterans Raynaud's Disease and Phenomenon ... Lipedema Erythromelalgia A rare syndrome of paroxysmal vasodilation with burning pain, increased skin temperature, and redness of the feet and, less often, the hands. The cause of primary erythromelalgia is unknown. Secondary erythromelalgia may occur in patients who have myeloproliferative disorders, hypertension, venous insufficiency, diabetes mellitus, SLE, RA, lichen sclerosus et atrophicus, gout, spinal cord disease, or multiple sclerosis. Diagnosis of erythromelalgia is based on the relationship of complaints to increased skin temperature. Secondary types should be differentiated from the rare primary type because correction of an underlying disorder may relieve symptoms. Differential diagnosis includes posttraumatic reflex dystrophies, shoulder-hand syndrome, causalgia, Fabry's disease, and bacterial cellulitis. Because erythromelalgia may precede a myeloproliferative disorder (even by several years), frequent blood counts may be indicated to allow early diagnosis and treatment of the latter. Attacks can be avoided or aborted by rest, elevation of the extremity, and cold applications. Therapy is not always successful. In primary erythromelalgia, aspirin 650 mg 1 to 4 times/day may provide prompt, prolonged relief. Avoiding factors that produce vasodilation is usually helpful, and vasoconstrictors (eg, ephedrine 25 mg po, propranolol 10 to 40 mg po qid, methysergide 1 mg po q 4 h) may also provide relief. In secondary erythromelalgia, the underlying disease should be treated.

3. EMedicine - Erythromelalgia : Article By Robert J Nardino, MD Background erythromelalgia is a rare disorder characterized by burning pain and warmth and redness of the extremities. http://www.emedicine.com/med/topic730.htm

(advertisement) Home Specialties CME PDA ... Patient Education Articles Images CME Patient Education Advanced Search Link to this site Back to: eMedicine Specialties Medicine, Ob/Gyn, Psychiatry, and Surgery Hematology Erythromelalgia Last Updated: August 6, 2002 Rate this Article Email to a Colleague Synonyms and related keywords: erythermalgia AUTHOR INFORMATION Section 1 of 11 Author Information Introduction Clinical Differentials ... Bibliography Author: Robert J Nardino, MD , Director, Internal Medicine Residency Program, Assistant Clinical Professor, Department of Internal Medicine, Hospital of Saint Raphael, Yale University School of Medicine Coauthor(s): Andrea LM Silber, MD , Fellowship Director of Oncology, Hospital of St Raphael; Clinical Assistant Professor, Department of Medicine, Section of Hematology-Oncology, Yale University School of Medicine Robert J Nardino, MD, is a member of the following medical societies: American College of Physicians-American Society of Internal Medicine , and Society of General Internal Medicine Editor(s): Rodger L Bick, MD, PhD

4. Erythromelalgia erythromelalgia If you have RED, BURNING, FEET or HANDS, check this page out!!! http://www.homestead.com/lareisaplaza/erythromelalgia.html

5. MESSAGES.TERADEX.COM - Health/Fitness/Diseases/Rare Disorders/Erythromelalgia MESSAGES / Health/Fitness / Diseases / Rare Disorders / erythromelalgia. Page 1 of 1 http://messages.teradex.com/Health_Fitness/Diseases/Rare_Disorders/Erythromelalg

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6. Erythromelalgia Diagnosis erythromelalgia Diagnosis. Medical Explanation and EM Life Style. Thefollowing medical rare. Raynaud's Syndrome and erythromelalgia. As the http://www.erythromelalgia.org/Diagnosis.asp

Erythromelalgia Diagnosis Medical Explanation and EM Life Style The following medical description should help you and your physician better understand this condition. Jay Cohen, MD, Chairman of TEA’s Medical Advisory Committee, defines Erythromelalgia in the following way: “EM results from a maldistribution of blood flow with some areas not getting enough blood and calling for more. The extra blood gets through other open vessels, including arteriovenous anastomosis, that is, the connection between the arterial and venous systems. This vicious cycle continues to worsen until the overall appearance of the skin is of too much blood flow. Vasodilating drugs sometimes work to open the shut vessels. When that happens, the vessels stop calling for more blood and the overall system may normalize or at least improve its function.” Dr. Cohen further says: “even mild erythromelalgia can greatly affect normal functioning and quality of life. Patients avoid warm weather and limit their activities to cool or air conditioned locations. Some move to cooler climates...many patients cannot wear socks or closed shoes even in winter.” When patients are severely affected, they can be house bound because of the continually painful symptoms. Elevation of the affected limbs becomes necessary and normal life is disrupted. Examples of various EM Flares: Before an EM flare-up. Skin color is often times a normal color. However, in some patients, the skin can become blistered due to constant or frequent flaring.

7. NORD Erythromelalgia Offers the synonyms, a general discussion and further resources. http://www.rarediseases.org/cgi-bin/nord/abstrfly?id=syce5dv4&mv_arg=RDB-245

8. Erythromelalgia Subscribe now . erythromelalgia. The doctor did some nerve conduction tests andsaid it was more likely a problem with blood vessels called erythromelalgia. http://healthlink.mcw.edu/article/990317252.html

Search Articles: search tips Please Take the HealthLink Survey Email this article Print this article Find related articles: By topic: Arthritis Feet By keywords: Receive Health Link via email! Subscribe now >> Erythromelalgia Q: I enjoy reading your column and your article discussing Raynaud's disease was of particular interest to me. However, my feet get extremely hot and red. Both plantar fasciitis and peripheral neuropathy were suggested as possibilities. After much frustration, I went to Marshfield Clinic. The doctor did some nerve conduction tests and said it was more likely a problem with blood vessels called erythromelalgia. I am still at a loss as to why I have it and what I can do to treat it. Is that the end of my story or can you tell me more about it and where I might find someone familiar with this very uncomfortable situation? A: You have a rare problem, that is almost the opposite of Raynaud's , in which the fingers and toes turn color and get painful with exposure to cold. With erythromelalgia, the hands and feet get very red and painful in a warm environment. It is more common in men and usually begins around middle age. The feet are usually more involved than the hands, especially when the feet are hanging down for long periods. Erythromelalgia may be associated with high blood pressure, too many platelets or red cells in the blood, or a side effect of medications like nifedipine (blood pressure medicine).

9. E-Doc: Erythromelalgia Medical Dictionary. erythromelalgia http://www.edoc.co.za/medilink/dict/1545.html

Medical Dictionary Erythromelalgia A circulatory disorder causing a burning sensation of the hands and/or feet, sometimes involving the whole extremity and lasting minutes or hours. Also called erythermalgia. Information last Updated: 1998-01-08 Contact Us E-Doc Send Questions and comments to the Pagemaster HTML by: E-Doc Reprohouse Last updated: 06 October 1999

10. Katalog - Wirtualna Polska Serwis Katalog w Wirtualna Polska S.A. pierwszy portal w Polsce. http://katalog.wp.pl/DMOZ/Health/Conditions_and_Diseases/Rare_Disorders/Erythrom

Poczta Czat SMS Pomoc Szukaj.wp.pl: -Katalog -Polskie www -¦wiatowe www -Wirtualna Polska -FTP/Pliki -Grupy dyskusyjne -Encyklopedia -Produkty wp.pl Katalog Katalog ¦wiatowy DMOZ ... Conditions and Diseases > Rare Disorders Fakty o Katalogu Pomoc Regulamin Serwis szukaj ... Ostatnio dodane NAWIGACJA Fakty o katalogu Pomoc Regulamin Serwis Szukaj ... FAQ Dodaj stronê Katalog WP Polskie Strony WWW Oferta dla firm WP-HIT ... Wirtualna Polska

11. EMedicine - Erythromelalgia : Article Excerpt By: Robert J Nardino, MD erythromelalgia erythromelalgia is a rare disorder characterized by burning painand warmth and redness of the extremities. Excerpt from erythromelalgia. http://www.emedicine.com/med/byname/erythromelalgia.htm

(advertisement) Excerpt from Erythromelalgia Synonyms, Key Words, and Related Terms: erythermalgia Please click here to view the full topic text: Erythromelalgia Background: Erythromelalgia is a rare disorder characterized by burning pain and warmth and redness of the extremities. Confusion exists in the literature concerning nomenclature and classification, but, in general, a distinction is made between primary (idiopathic) and secondary erythromelalgia (most commonly associated with myeloproliferative disorders), as well as early- and late-onset disease. erythros (red), melos (extremities), and algos (pain). In 1938, Smith and Allen proposed the term erythermalgia to emphasize the characteristic warmth. They also proposed a distinction between primary (idiopathic) and secondary (due to underlying neurologic, hematologic, or vascular problems). Pathophysiology: Arteriolar fibrosis and occlusion with platelet thrombi occur, but not in all cases. Platelets have been demonstrated to have abnormal hyperaggregability. Platelet kinetic studies show decreased platelet survival, predominantly due to consumption. Prostaglandins and cyclooxygenase apparently play an important pathogenetic role. Pathophysiology in cases not associated with thrombocythemia is less clear but does not involve platelet-mediated inflammation and thrombosis. This is the major reason that Drenth and Michiels distinguish between erythromelalgia and erythermalgia. One postulate is maldistribution of skin perfusion resulting from arteriovenous shunting, leading to an imbalance between thermoregulatory and nutritive perfusion. Another is decreased sympathetic vasoconstrictor response to certain stimuli.

12. Homemade Poetry com/ Health/ Conditions_ and_ Diseases/ Rare_ Disorders /erythromelalgia.htm. Notice Microsoft has no responsibility http://groups.msn.com/HomemadePoetry/erythromelalgia.msnw

MSN Home My MSN Hotmail Search ... Money Groups Homemade Poetry HomemadePoetry@groups.msn.com Groups Home My Groups Language Help ... Tools ~~~ERYTHROMELALGIA~~~ dedication to two family members written by Marie~ May 19th 2002 http://www.erythromelalgia.org/ http://www.homestead.com/lareisaplaza/eryfaqs.html http://www.emedicine.com/med/topic730.htm http://www.slider.com/Health/Conditions_and_Diseases/Rare_Disorders ... /Erythromelalgia.htm Notice: Microsoft has no responsibility for the content featured in this Group. Click here for more info. MSN - More Useful Everyday MSN Home My MSN ... GetNetWise

13. Erythromelalgia erythromelalgia Menu. This is a webforum to discuss and comment on erythromelalgia. Nueropathy erythromelalgia (4/16/99) 1225 AM; (4/8/99) 113 AM; HELP! http://neuro-www.mgh.harvard.edu/forum/ErythromelalgiaMenu.html

Erythromelalgia Menu This is a webforum to discuss and comment on Erythromelalgia. Click here to Enter a new Neurology WebForum article... This Web Forum is not moderated in any sense. Anyone on the Internet can post articles or reply to previously posted articles, and they may do so anonymously. Therefore, the opinions and statements made in all articles and replies do not represent the official opinions of MGH and MGH Neurology. Neither is MGH or MGH Neurology responsible for the content of any articles or replies. No messages are screened for content. - Very Important Message! - Please Click Here to Read Current Posts: Nov 13, 1997 to Present Useful Websites can be found and posted here! Erythomelalgia (1/1/00) 9:50 AM New MGH Neurology Webforum! (12/30/99) 7:22 PM forum working OK now (12/27/99) 1:09 PM ... Can someone tell me? (11/17/97) 3:49 AM IMPORTANT: If this page seems to be missing recently added documents, click the "Reload Page" button on your Web Browser to update the menu. Return to the main Neurology WebForum Page. These forums are maintained by the Department of Neurology at Massachusetts General Hospital John Lester - Webspinner

14. Erythromelalgia Types And Treatments erythromelalgia Types and Treatments. This article submitted by Karl Granat on10/13/98. Email Address katlgra@aol.com Form letter on erythromelalgia http://neuro-www.mgh.harvard.edu/forum/ErythromelalgiaF/10.13.981.41PMErythromel

Erythromelalgia Types and Treatments This article submitted by Karl Granat on 10/13/98. Email Address: katlgra@aol.com Form letter on Erythromelalgia: Welcome!!! We wish to introduce you to our informal group on erythromelalgia (EM). What is Erythromelalgia? Erythromelalgia is a painful condition that has a very distinctive pattern of symptoms. It is diagnosed when the extremities are red, warm and painful- the pain is often described as burning. This pain is only relieved by cooling (often in cold water) or the elevation of the affected extremities. Secondary Erythromelalgia: This condition often accompanies tissue destroying disorders such as arthritis, lupus, or diabetes. It also often associated with potentially fatal disorders of the blood as well- which is why all who suffer from these symptoms should seek a diagnosis and treatment from a physician and have periodic blood tests thereafter. Secondary erythromelalgia can very often be treated successfully by your physician. Primary Erythromelalgia: Where no cause can be found, the condition is called primary erythromelalgia. Primary erythromelalgia is typically difficult to treat. This should be diagnosed by a physician in order to rule out some underlying disease process.

15. DIRECTORY.TERADEX.COM - Health/Fitness/Diseases/Rare Disorders/Erythromelalgia Groups A support group for those willing to help others who have erythromelalgia. Includes joining instructions. http://directory.teradex.com/Health_Fitness/Diseases/Rare_Disorders/Erythromelal

preloadImages('as_free_x-mail_s','as_anonymous','as_ad-space'); Add your Web Site Add Search to your Site Search for: Search through: Entire site Erythromelalgia DIRECTORY Health/Fitness Diseases Rare Disorders ... EM at Yahoo! Groups - A support group for those willing to help others who have Erythromelalgia. Includes joining instructions. Erythromelalgia in The Merck Manual - A basic description of this disorder, which causes severe burning, pain, and redness, primarily in the hands and feet. NORD: Erythromelalgia - Offers the synonyms, a general discussion and further resources. The Erythromelalgia Association - A non-profit organization dedicated to research and education regarding this painful disorder. Offers details about the disorder, the organization, FAQs and membership information. Submit Premium Listing! $10 for two years Sign Up User Name: Password: Edit in Real Time, Banner Placement Help build the largest human-edited directory on the web. Submit a Site Open Directory Project Become an Editor This site is presented in modified Open Directory form E-Mail: webmaster@teradex.com

16. Erythromelalgia Subject erythromelalgia Topic Area Heart Disease Forum The Heart Forum QuestionPosted By Del on Monday, January 11, 1999 I don't even know for sure if http://www.medhelp.org/forums/cardio/archive/7658.html

Advertisement Heart Forum Sponsor Developed with The American Heart Association, Med Help and Nexcura encourage you to log on to the FREE Heart Profiler and take advantage of this helpful tool. Med Help International A not-for-profit organization Questions in The Heart Forum are being answered by doctors from The Cleveland Clinic Heart Center , consistently ranked the #1 Heart Center in America. Subject: Erythromelalgia Topic Area: Heart Disease Forum: The Heart Forum Question Posted By: Del on Monday, January 11, 1999 I don't even know for sure if this is the correct forum, my searches at many sites come up empty, but since Erythromelalgia is connected to problems with the vascular system, I decided to try here. I'm trying to find GOOD, basic information/explanations for Erythromelalgia. I have been diagnosed but without any clear understanding as to what this will mean - prognosis. It is secondary to peripheral neuropathy, but doesn't seem to be a neurological disorder, although many of the symptoms overlap. I'm confused! I'll appreciate any help you can give me. Thanks! Dear Del

17. Erythromelalgia Articles, Support Groups, And Resources erythromelalgia articles, support groups, and resources for patientsfrom Med Help International (www.medhelp.org). erythromelalgia. http://www.medhelp.org/HealthTopics/Erythromelalgia.html

[Health Topics A-Z] A B C D ... Z Erythromelalgia Ask The Doctor Forums Erythromelalgia (Heart Forum) burning and itching on palms and soles (Dermatology Forum) Support Groups: The Erythromelalgia Association (TEA) [Med Help Home] [Library Search] [Medical Forums] ... [Patient Network] Revised: 3/30/2003

18. Arch Dermatol -- Page Not Found Arch Dermatol. 136;406409, March 2000, erythromelalgiaA Mysterious Condition?,Cato Mork, MD; Knut Kvernebo, PhD. erythromelalgia A Mysterious Condition? http://archderm.ama-assn.org/issues/v136n3/ffull/ded9027.html

Select Journal or Resource JAMA Archives of Dermatology Facial Plastic Surgery Family Medicine (1992-2000) General Psychiatry Internal Medicine Neurology Ophthalmology Surgery MSJAMA Science News Updates Meetings Peer Review Congress The page you requested was not found. The JAMA Archives Journals Web site has been redesigned to provide you with improved layout, features, and functionality. The location of the page you requested may have changed. To find the page you requested, click here HOME CURRENT ISSUE PAST ISSUES ... HELP Error 404 - "Not Found"

19. Arch Dermatol -- Page Not Found Natural History of erythromelalgia Presentation and Outcome in 168 Patients AuthorInformation Mark DP Davis, MB, MRCPI; W. Michael O'Fallon, PhD; Roy S http://archderm.ama-assn.org/issues/v136n3/abs/dst9040.html

Select Journal or Resource JAMA Archives of Dermatology Facial Plastic Surgery Family Medicine (1992-2000) General Psychiatry Internal Medicine Neurology Ophthalmology Surgery MSJAMA Science News Updates Meetings Peer Review Congress The page you requested was not found. The JAMA Archives Journals Web site has been redesigned to provide you with improved layout, features, and functionality. The location of the page you requested may have changed. To find the page you requested, click here HOME CURRENT ISSUE PAST ISSUES ... HELP Error 404 - "Not Found"

20. New Page 4 The symptoms you describe are classic for something called *erythromelalgia*,which literally means red, painful extremities. erythromelalgia http://www.the-doctors-inn.com/newpage4.htm

QUERY: In the past 4-5 yrs. any increase in body temperature(even slightly) ex.. wearing a sweater, drinking hot coffee, going inside during the winter or working inside all day if its too warm... causes my hands to swell and turn very red. It's almost painful. Now I'm noticing my feet are doing this as well. I haven't always been this way, I used to wear sweaters constantly,sleep with an electric blanket. Now I can't go in the sun in moderate heat with out being miserable. My doctors ran some tests, Its not diabetes, thyroid disorder, blood pressure, or glandular related, so they say. My allergies are, sulfa, shellfish, codiene are amoxicillian (for acne) 1 and 1/2 yrs. Celexa 30 mg for 8 months. If the temp decreases I am not as miserable, but still not normal. This is getting very frustrating and the doctors think I'm looney . I'm getting scared, It's very uncomfortable and is keeping me from being in a lot of situations. ANSWER: I'm glad you are pursuing the answers for your problem, especially since it seems to be getting worse with time. So far, so good - the thyroid

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