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         Extrapontine Myelinolysis:     more detail
  1. Methylphenidate Treatment of Neuropsychiatric Symptoms of Central and Extrapontine Myelinolysis(*).: An article from: Journal of Studies on Alcohol by Denise Bridgeford, David B. Arciniegas, et all 2000-09-01

41. Open Classes's $p->page_title
extrapontine myelinolysis@ (3); Eye Cancer@ (14). Help build the largesthumanedited directory on the web. Submit a Site - Open Directory
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42. Society Of General Internal Medicine
with hemosiderosis. A Davis, L Willett; extrapontine myelinolysisafter rapid correction of hyponatremia. G Falchook, L Lu; Syncope
News Member's Only Society Information Publications ... JGIM



Mountain West
Texas Chapter

February 20-22, 2003
The Hyatt Regency New Orleans THURSDAY FEBRUARY 20, 200 1:00 pm-5:00 pm Joint Precourse with AFMR FRIDAY, FEBRUARY 21, 2003 7:00 am-4:00 pm REGISTRATION Burgundy Balcony 7:00 am-8:00 am CONINENTAL BREAKFAST, Burgundy Balcony 8:00 am-9:30 am Abstract Session, Health Services Research, Rampart
  • Utilization of Resources in Patients with Chronic Non-Malignant Pain. AJ Mechaber, EI Rosenberg Characteristics related to increased Chronic Non-Malignant Pain Perception. Barriers to Colorectal Cancer Screening in a United States-Mexico Border Population. RM Tyroch,, L Kim, S Prasad, BK Nelson, BC Pence, M Ortiz Are Clinicians aware of computer reminders to implement practice guidelines? A National Survey. AA James, RI Shorr, S Flach, C Franciscus, T Vaughn, B BootsMiller, BN Doebbeling PF Bass, BA Stetson, B Rising, GC Wesley, CS Ritchie Patient preferences for arthritis care among urban African Americans MK Figaro, P Williams-Russo, JP Allegrante

43. (8[3]:579-583) Biology Of Neurologic Disease Meeting - 1998
Central pontine and extrapontine myelinolysis is a human disease which symmetricallyaffects characteristic regions of the brain such as the center of the

Biology of Neurologic Disease Meeting - 1998 Sponsored by the Society for Experimental Neuropathology
Neurohistology of Scrapie in Hamsters: Degeneration-Selective Methods.
A.C. Scallet , X. Ye , L.C. Schmued , R.I. Carp Jefferson, AR, Staten Island, NY Regulation of Presenilin-1 During Neuronotypic Differentiation of PC12 Cells S.E.Counts, J.J. Lah, A.I.Levey
Department of Neurology, Emory University, Atlanta GA The most clearly identified roles for Alzheimer's disease (AD) protein presenilin-1 (PS1) in neurons are in development and in the generation of b -amyloid. The functional homology of PS1 with the C. elegans Localization of Borrelia Burgdorferi in the Peripheral and Central Nervous System of the Non-human Primate Model of Lyme Disease D.Cadavid , A.R. Pachner , T. O'Neill
Georgetown University, Georgetown University, Armed Forces Institute of pathology, Washington D.C. Lyme disease is a multisystemic disease caused by the spirochete Borrelia burgdorferi . About 15% of patients develop neurologic complications including meningitis, cranial neuritis, peripheral neuropathy, and myopathy, for which the pathogenesis is poorly understood. The purpose of this study was to determine the localization and approximate number of organisms in the central (CNS) and peripheral nervous system (PNS) and other organs during experimental infection. For this we used immunocompetent (N=2) and steroid-immunosupressed (N=2) Maccaca mulatta infected intradermally with 1 million spirochetes of the N40Br strain of

In severe cases, the lesion becomes necrotic and extends to the cerebral hemispheres(extrapontine myelinolysis). CPM is usually an incidental autopsy finding.
Table of contents


Demyelinative diseases of the central nervous system are characterized by loss of myelin with variable loss of axons. In contrast, infarcts, contusions, encephalitis and other conditions destroy myelin and axons equally. The main demyelinative disease of the CNS is multiple sclerosis (MS) and its variants. Its counterpart in the peripheral nervous system is inflammatory demyelinative polyradiculoneuropathy ( Guillain-Barré syndrome-GBS ) and its chronic variants. MS and GBS are autoimmune inflammatory diseases. There are also virus-induced demyelinative diseases. Demyelinative diseases should be distinguished from leukodystrophies, which are inherited metabolic disorders of myelin lipids. MULTIPLE SCLEROSIS AND VARIANTS MS affects one in every 500 persons, women twice as frequently as men. It is more frequent in young adults and causes a variety of neurological deficits (visual loss, paralysis, sensory loss, ataxia, nystagmus, psychiatric disorders, dementia). The clinical course of MS is unpredictable. Many cases have a long course (20-30 years), with remissions and exacerbations. Some cases have an acute, fulminant, even fatal course and others go into a relentlessly progressive phase after a period of remissions and exacerbations.

45. E Website Results :: Linkspider UK
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    47. Hyponatraemia: Common Causes Were Heart Failure And Iatrogenic.
    part due to overly rapid correction of patients with chronic hyponatremia which probablyresulted in central pontine and extrapontine myelinolysis causing coma
    Hyponatraemia: common causes were heart failure and iatrogenic.
    Clinical bottom line (level 4)
  • Mortality was higher in patients with acute onset hyponatraemia or symptomatic hyponatraemia. The commonest causes of hyponatraemia were congestive heart failure, iatrogenic causes (fluid overload or diuretics) and SIADH.
  • Arieff et al: Medicine 1976; 55 (2): 121-129
    Expires July 2005 The study Case series with ?objective ?blinded outcomes, not adjusted for confounding factors, not validated in an independent set of patients.
    Setting: university hospital, USA
    Outcomes studied:
  • mortality with chronic symptomatic hyponatraemia mortality with asymptomatic hyponatraemia cause: congestive heart failure cause: SIADH cause: post-surgical (overtransfusion with 5% dextrose) fluid overload cause: dieuretic use usually due to diuretic use cause: chronic renal failure cause: acute renal failure

  • The evidence outcome time to outcome number of patients/total number
    (95% CI) mortality with acute hyponatraemia
    (24% to 76%) mortality with chronic symptomatic hyponatraemia
    (0.0% to 25%)

    48. ?
    of Neurology, 3ed , McGrawHill Kook Co, New York , 1985, 778-780 2 Menger H,Jorg J. Outcome of central pontine and extrapontine myelinolysis J Neurol.

    49. Korsakov's Journal Of Neurology And Psychiatry - Contents ¹2 2000
    morphogenesis. Clinical notes. Stakhovskaya LV, Erokhina LG, LeskovaNN, Gubsky LV Central pontine and extrapontine myelinolysis. Sidorov
    Korsakov's journal of neurology and psychiatry ¹
    The 100-th anniversary of “Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova”
    What did the journal report during the 1-st year of its existence Clinical aspects of nervous and mental diseases Morenkova A.E., Orlova O.R., Dubanova E.A.
    Clinical physiologic analysis of cranial dystonia
    Ivanov S.V., Andreev A.M.
    Typologic differentiation of chronic agoraphobia
    Personal behaviour and mental state in anorexia nervosa
    Treatment of nervous and mental diseases Martynov Yu.S., Surskaya E.V., Malkova E.V., Shuvakhina N.A.
    Follow-up study of the patients operated for traumatic subdural hematomas
    Kazmina O.Yu., Chemekova E.B., Savenko G.V., Vladimirova T.V., Tsutsulkovskaya M.Ya., Oleichik I.V.
    The role of group psychocorrective method in combined therapy of juvenile endogenic depressions
    Methods of investigation and diagnosis Gnezditsky V.V., Fedin P.A., Poleschuk V.V., Markova E.D., Ivanova- Smolenskaya I.A.
    Acoustic brain stem and cognitive evoked potentials (P300) in patients with hepatolenticular degeneration
    Experimental and theoretical problems Golimbet V.E., Manandyan K.K., Abramova L.I., Orlova V.A., Kaleda V.G., Oleichik I.V., Yurov Yu.B., Trubnikov V.I.

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    51. ¹«Á¦¸ñ
    . Central Pontine Myelinolysis with extrapontine myelinolysisA caseReport. . ?, ?, ?, ?. ?.
    Bladder Management in Children with Spinal Cord Injuries
    The Significane of Somatosensory Evoked Potential as Prognostic Factor in patients of diffuse Axonal Injury
    The Median Nerve Somatosensory Evoked Potentials as prognostic Factor in the Hemiplegic Tatients
    Passive ROM Evaluation in Hemiplegic Shoulder Following Tigger Point Injection
    A Study on Electrodiagnosis of Peripheral Neuropathy and Reflex Sympathetic Dystrophy in Memiplegic patients
    A Study on the Relationship of Carpal Tunnel Syndrome and Polyneuropathy in Diabetes Mellitus
    ¸»Ê ½Å°æ Áõ»óÀ» µ¿¹ÝÇÑ ´ç´¢º´ ȯÀÚ¿¡¼­ FÆÄ °Ë»çÀÇ ÀÇÀÇ F-wave Study on the patients with Diabetic Neuropathy
    A Study of Electrodiagnostic Sensitivity for Diagnosis of Diabetic Neuropathy
    Predisposing Factors in Neck and Back pain and the Effectiveness of Education
    A Comparative Study of Straight Leg Raising Test Versus Electromyologidc Findings and Radiologic Study in Low Back Pain
    Pain Drawing and Low Back Pain A Study of Psychometric Characteristics and pain Behaviors in Low Back Pain Patients Clinical Evaluation of Dysphagia in Stroke patients91) Functional Evaluation of Aphasia in the Stroke Patients Measurement of Thoracolumbar Motion Using 2-Dimensional Motion Analysis System in Normaal Adults Normal Cervical and Lumbar Range of Motion and Influence of Age

    52. Syndrome Of Inappropriate ADH
    WORDS). Pontine and extrapontine myelinolysis a neurologic disorderfollowing rapid correction of hyponatremia. Karp BI, Laureno R.
    Background SIADH stands for syndrome of inappropriate anti-diuretic hormone. The abnormal production of this hormone ADH, leads to salt wasting, or hyponatremia. The result is a profound metabolic disturbance which may result in coma and death. The pathologist is often called upon to investigate a laboratory abnormality of serum hypo-osmolality, an unexpectedly high urinary specific gravity, an absence of edema or dehydration, hyponatremia, and an elevation of plasma vasopressin. Usually there is normal adrenal, thyroid, and renal function. Occasionally the syndrome is due to head trauma or a tumor. In these cases, the pathologist may be called upon to evaluate a tissue biopsy to confirm the diagnosis. OUTLINE Epidemiology Amiodarone
    Psychotropic drugs
    Vincristine Disease Associations Head and neck cancer
    Lung cancer
    Pneumonia Laboratory/Radiologic/Other Diagnostic Testing Gross Appearance and Clinical Variants Geriatric Differential Diagnosis Cerebral salt wasting syndrome Prognosis Central pontine myelinolysis Treatment Vasopressin Receptor Antagonist Commonly Used Terms Internet Links EPIDEMIOLOGY CHARACTERIZATION SYNONYMS Schwartz-Bartter syndrome INCIDENCE/PREVALENCE Probably more common than reported AGE
    Chronic idiopathic hyponatremia in older people due to syndrome of inappropriate antidiuretic hormone secretion (SIADH) possibly related to aging.

    53. Table Of Contents Receive Table Of Contents Via E-mail Abstracts
    extrapontine myelinolysis and Behavioral Change after Transsphenoidal PituitarySurgery Case Report, Masahiko Tosaka, MD; Hideaki Kohga, MD, 933.
    Table of Contents Receive
    Table of Contents

    via e-mail
    Abstracts Full-Text January February March April ... September October November December Volume 43, Number 4 Article Title Author(s) Page Fundamental Problems Abstract


    Craniocerebral Trauma: Protection and Retrieval of the Neuronal Population after Injury Graham Michael Teasdale, F.R.C.P., F.R.C.S.; David Ian Graham, F.R.C.Path. Clinical Study Abstract


    Intraoperative Magnetic Resonance Imaging with the Magnetom Open Scanner: Concepts, Neurosurgical Indications, and Procedures: A Preliminary Report Ralf Steinmeier, M.D.; Rudolf Fahlbusch, M.D.; Oliver Ganslandt, M.D.; Christopher Nimsky, M.D.; Michael Buchfelder, M.D.; Michael Kaus, Dipl.-Ing.; Thomas Heigl, Gerald Lenz, Ph.D.; Rainer Kuth; Walter Huk, M.D. Abstract

    Intraoperative Brain Shift and Deformation: A Quantitative Analysis of Cortical Displacement in 28 Cases David W. Roberts, M.D.; Alexander Hartov, Ph.D.; Francis E. Kennedy, Ph.D.; Michael I. Miga, M.S.; Keith D. Paulsen, Ph.D. Abstract Full-Text Print Long-term Graft Patency Rates and Clinical Outcomes after Revascularization for Symptomatic Traumatic Internal Carotid Artery Dissection A. Giancarlo Vishteh, M.D.; Frederick F. Marciano, M.D., Ph.D.; Carlos A. David, M.D.; Wouter I. Schievink, M.D.; Joseph M. Zabramski, M.D.; Robert F. Spetzler, M.D.

    54. Fylgirit 43 Maí 2002 - Neurology Congress
    neurological disease. P13 Central extrapontine myelinolysis due to polydipsiacausing basal ganglia dysfunction with Parkinsonism. A case

    55. UNMC Faculty Information System
    Markin RS. Pontine and extrapontine myelinolysis following livertransplantation. Relationship to serum sodium. Transplantation

    56. Neuros
    Tosaka, M., Kohga, H.(1998) extrapontine myelinolysis and behavioral changeafter transsphenoidal pituitary surgery case report Neurosurgery 43933936.
    Department of Neurosurgery
    ”]_ŒoŠO‰ÈƒWƒƒ[ƒiƒ‹7:358-359 ˆäã@—mA‚‹´Í•vA•½ŒË­ŽjAŽÄè@“OAŽÄ“cM‹`A‹v•Û“c•¶—YA‘å]çœAi1998j
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    Lesional epilepsy ‚ɑ΂·‚éminimally invasive surgery: Dipole tracing –@‚Ægamma knife b‰ê‰p–¾Aˆäã@—mAŽë–ì—FºA“¡ŠªL–çA•½ŒË­ŽjAŽÄè@“OA‘å]çœAi1998j
    The Japanese Society for Stereotactic Radiosurgery@2:43-51 ‚‹´Í•vA“n•ÓŽ¬A•½ŒË­ŽjA‘å]çœAi1998j •½ŒË­ŽjA‘å]çœAi1998j •½ŒË­ŽjA‘å]çœAi1998j
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    ‘æ‚Q‚R‰ñãM‰z_Œo•a—§’k‰ï‹L˜^@48:254-255 Imai, H., Tamura, M., Zama, A., Kohga, H. and Nakazato, Y.i1998j
    Olfactory neuroblastoma with nasal and suprasellar extention: A case report
    Kitakanto Med. J. 48:53-57 Inoue, H. K., Negishi, M., Hirato, M. and Ohye, C.i1998j
    Treatment of unruptured arteriovenous malformations in the brain
    J Clin Neuroscience 5:61-64 Inoue, K. H., Negishi, M., Kohga, H., Hirato, M., Shibazaki, T. and Ohye, C.i1998j

    57. ¥xÆW¯«¸g¾Ç¥»¤g¸ê®Æ
    51. CJ Chen, ChinChang Huang, LS Lo. Evolution of pontine and extrapontine myelinolysisclinical correlation with serial CT and MRI studies. Eur Neurol.
    ¹B°Ê»Ùª¾Ç²Õ ¶ÀÀA³¹ ¦^¤W¤@­¶ ½s¸¹ Yung-Kuei Soong, Horng-Yuan Huang, Chin-Chang Huang , Nai-Shin Chu: Successful pregnancy after D-penicillame theraphy in a patient with Wilson's disease. J Formosan Med Assoc 1991;90:693-696. Nai-Shin Chu, Chen-Chung Chu, Shu-Chen Tu, Chin-Chang Huang EEG spectral analysis and tographic mapping in Wilson's disease. J Neurol Sci Chin-Chang Huang , Nai-Shin Chu: Wilson's disease: Resolution of cerebral white matter lesions following long-term penicillamine therapy. J Formosan Med Assoc 1992;91:627-629. Chin-Chang Huang, Nai-Shin Chu: Wilson's disease: Clinical analysis of 71 cases and comparison with previous Chinese series. J Formosan Med Assoc 1992;91:502-507. Chin-Chang Huang , Chin-Song Lu, Nai-Shin Chu, F.H.Hochberg, D. Lilienfeld, D.B. Calne: Pathogensis of idiopathic Parkinsonism. In: Controversies in the treatment of Parkinson's disease. U.K. Rinne, N Yanagisawa, eds. PMSI, Tokyo. pp.7-13,1992.

    58. Pracownia Farmakologii Do¶wiadczalnej
    3. BekiesinskaFigatowska M, Bulski T, Rozyczka I, Furmanek M, Walecki J. MR imagingof seven presumed cases of central pontine and extrapontine myelinolysis.
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    59. Untitled Document
    53. Wszolek ZK, McComb RD, Pfeiffer RF et al. Pontine and extrapontine myelinolysisfollowing liver transplantation. Transplantation 48 1006—12. 1989. 54.
    Trasplante hepático Manejo en la Unidad de Cuidados Intensivos Una Opinión de dos Continentes BIBLIOGRAFÍA 1.   Plevak DJ, Southorn PA, Narr BJ et al . Intensive care unit experience in the Mayo liver transplantation program: the first 100 cases. Mayo Clin Proc 2.   Singh N, Gayowski T, Wagener MM. Intensive care unit management in liver transplant recipients: beneficial effect on survival and preservation of quality of life. Clin Transplantation 3.   Atchinson SR, Rettke SR, Fromme GA et al . Plasma glucose concentrations during liver transplantation. Mayo Clinic Proc 4.   Gray PA, Bodenham R, Park GR. A comparison of Dopexamine and Dopamine to prevent renal impairment in patients undergoing orthotopic liver transplantation. Anaesthesia 5.   Eisenach JC, Plevak DJ, Van Dyke RA et al . Comparison of analgesic requirements after liver transplantation and cholecystectomy. Mayo Clinic Proc. 6.   Paya CV, Hermans PE, Washington JA II et al . Incidence distribution and outcome of episodes of infection in 100 orthotopic liver transplantation. Mayo Clinic Proc 7.   The US Multicenter FK 506 liver study group. A comparison of tacrolimus (FK 506) and cyclosporin for immunosuppression in liver transplantation.

    60. [Dysphagia] Central Pontine Myelinosis
    Go M; Amino A; Shindo K; Tsunoda S; Shiozawa Z . A case of central pontine myelinolysisand extrapontine myelinolysis during rapid correction of hypernatremia.

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