1. Microscopic Polyangiitis: Savvy Medinfo For Patients And Doctors:E-lists,contact microscopic polyangiitis lacks the immune complex deposition in the blood vessels seen in SchönleinHenoch purpura and http://www.blackandwhite.org/micro/index.shtml

Savvy Home Subscribe About Vasculitis Patient Gateway Central Nervous System Churg-Strauss syndrome Giant-cell (temporal) arteritis Leukocytoclastic vasculitis Microscopic polyangiitis Overlapping syndromes Pediatrics Polyarteritis nodosa Takayasu's arteritis Wegener's granulomatosis Links, Resources... Focus News Focus Chinese Medical Diagnosis Opinion Subscribers Mailing List FAQ How to Subscribe Savvy Site Info Welcome Medical Search Gateway Search Microscopic polyangiitis is a systemic small to medium vessel vasculitis, involving the skin, lungs, gastrointestinal tract, and kidneys. Patients commonly present with palpable purpura (blood spots, bruising and discolouration to skin) hemoptysis (coughing up blood) abdominal pain or renal (kidney) insufficiency. Microscopic polyangiitis lacks the immune complex deposition in the blood vessels seen in Schönlein-Henoch purpura and the upper airway involvement and granulomas present in Wegener's granulomatosis. Also, unlike in polyarteritis nodosa, no aneurysms are detected on angiography. Diagnosis The diagnosis is confirmed on biopsy of the involved organ. Half of patients have positive titers of ANCA (of both the c-ANCA and p-ANCA type). Treatment of microscopic polyangiitis is the same as that of

2. Arch Fam Med -- Page Not Found From Archives of Family Medicine, a description of this disorder, followed by a case study.Category Health Conditions and Diseases microscopic polyangiitis......microscopic polyangiitis in a Pediatric Patient Author Information Ala'addin Kandeel,MD; Sujatha Ramesh, MD; Yongxin Chen, MD; Cazibe Celik, MD; Edwin Jenis http://archfami.ama-assn.org/issues/current/abs/fbf0009.html

Select Journal or Resource JAMA Archives of Dermatology Facial Plastic Surgery Family Medicine (1992-2000) General Psychiatry Internal Medicine Neurology Ophthalmology Surgery MSJAMA Science News Updates Meetings Peer Review Congress The page you requested was not found. The JAMA Archives Journals Web site has been redesigned to provide you with improved layout, features, and functionality. The location of the page you requested may have changed. To find the page you requested, click here HOME CURRENT ISSUE PAST ISSUES ... HELP Error 404 - "Not Found"

3. Rachael's MPA Support Site Support and information for people fighting microscopic polyangiitis. Frequently asked questions and dealing with doctors are a few of the topics discussed. http://www.users.fast.net/~rcb1/mpa/

Welcome to my Microscopic Polyangiitis Support Site. I created this site to offer people with this disease a place to come for information about the condition and also a place to share their experiences with someone who understands. I have been searching for an MPA support Web site for the past few years and I haven’t found one, so I thought I’d create my own. Since I started this site in Fall 2000, I’ve heard from a few others who have MPA. We’re not alone! (We’re rare, but we’re not alone.) I want to provide a place where people around the world with MPA can share useful information and offer support to one another. Come on in and look around. Learn a little. Send me some feedback , or even share your own story. Rachael Last Modified Saturday, May 19, 2001 What is Microscopic Polyangiitis? Microscopic Polyangiitis, or MPA, is a disease that causes inflammation of small blood vessels and capillaries in the body. It is an autoimmune disease, which means that the inflammation comes from the body’s immune system and not from an outside bacteria or virus. For more information about MPA, go to the

4. Arch Fam Med -- Page Not Found 9;11891192, November/December 2000, microscopic polyangiitis in a Pediatric Patient,Ala'addin Kandeel, MD; Sujatha Ramesh, MD; Yongxin Chen, MD; Cazibe Celik http://archfami.ama-assn.org/issues/current/ffull/fbf0009.html

Select Journal or Resource JAMA Archives of Dermatology Facial Plastic Surgery Family Medicine (1992-2000) General Psychiatry Internal Medicine Neurology Ophthalmology Surgery MSJAMA Science News Updates Meetings Peer Review Congress The page you requested was not found. The JAMA Archives Journals Web site has been redesigned to provide you with improved layout, features, and functionality. The location of the page you requested may have changed. To find the page you requested, click here HOME CURRENT ISSUE PAST ISSUES ... HELP Error 404 - "Not Found"

5. EMedicine - Microscopic Polyangiitis : Article Excerpt By: Mehran Farid-Moayer, microscopic polyangiitis microscopic polyangiitis (MPA) is vasculitis ofsmall vessels. (advertisement). Excerpt from microscopic polyangiitis. http://www.emedicine.com/med/byname/microscopic-polyangiitis.htm

(advertisement) Excerpt from Microscopic Polyangiitis Synonyms, Key Words, and Related Terms: MPA, small vessel vasculitis, microscopic polyarteritis nodosa, microscopic PAN, small vessel vasculitides, systemic vasculitis, Wegener granulomatosis, Churg-Strauss syndrome Please click here to view the full topic text: Microscopic Polyangiitis Background: Microscopic polyangiitis (MPA) is vasculitis of small vessels. It was initially recognized as a microscopic form of polyarteritis nodosa (PAN). In 1990, the American College of Rheumatology developed classification criteria for several types of systemic vasculitis but did not distinguish between PAN and microscopic PAN. In 1994, a group of experts held an international consensus conference in Chapel Hill, North Carolina to attempt to redefine the classification of small vessel vasculitides. The proposed feature distinguishing PAN from MPA is the absence of vasculitis in small vessels, including arterioles, capillaries, and venules, in patients with PAN and the presence of small vessel vasculitis in patients with MPA. A category of small vessel vasculitis that is related to antineutrophil cytoplasmic antibodies (ANCA) and is characterized by a paucity of immune deposits includes 3 diseases of MPA, Wegener granulomatosis, and Churg-Strauss syndrome. Pathophysiology: Vasculitis is inflammation of the vessel walls. MPA is characterized by pauci-immune, necrotizing, small-vessel vasculitis without clinical or pathological evidence of necrotizing granulomatous inflammation.

6. EMedicine - Microscopic Polyangiitis : Article By Mehran Farid-Moayer, MD microscopic polyangiitis microscopic polyangiitis (MPA) is vasculitisof small vessels. microscopic polyangiitis. Last Updated May 3, 2002, http://www.emedicine.com/med/topic2931.htm

(advertisement) Home Specialties CME PDA ... Patient Education Articles Images CME Patient Education Advanced Search Link to this site Back to: eMedicine Specialties Medicine, Ob/Gyn, Psychiatry, and Surgery Rheumatology Microscopic Polyangiitis Last Updated: May 3, 2002 Rate this Article Email to a Colleague Synonyms and related keywords: MPA, small vessel vasculitis, microscopic polyarteritis nodosa, microscopic PAN, small vessel vasculitides, systemic vasculitis, Wegener granulomatosis, Churg-Strauss syndrome AUTHOR INFORMATION Section 1 of 10 Author Information Introduction Clinical Differentials ... Bibliography Author: Mehran Farid-Moayer, MD , Fellow, Department of Internal Medicine, Section of Pulmonary and Critical Care, Baylor College of Medicine Mehran Farid-Moayer, MD, is a member of the following medical societies: American College of Chest Physicians American College of Physicians-American Society of Internal Medicine American Medical Association , and American Thoracic Society Editor(s): Bryan L Martin, DO

7. EMedicine - Microscopic Polyangiitis : Article By Mehran Farid-Moayer, MD Background microscopic polyangiitis (MPA) is vasculitis of small vessels. http://www.emedicine.com/MED/topic2931.htm

(advertisement) Home Specialties CME PDA ... Patient Education Articles Images CME Patient Education Advanced Search Link to this site Back to: eMedicine Specialties Medicine, Ob/Gyn, Psychiatry, and Surgery Rheumatology Microscopic Polyangiitis Last Updated: May 3, 2002 Rate this Article Email to a Colleague Synonyms and related keywords: MPA, small vessel vasculitis, microscopic polyarteritis nodosa, microscopic PAN, small vessel vasculitides, systemic vasculitis, Wegener granulomatosis, Churg-Strauss syndrome AUTHOR INFORMATION Section 1 of 10 Author Information Introduction Clinical Differentials ... Bibliography Author: Mehran Farid-Moayer, MD , Fellow, Department of Internal Medicine, Section of Pulmonary and Critical Care, Baylor College of Medicine Mehran Farid-Moayer, MD, is a member of the following medical societies: American College of Chest Physicians American College of Physicians-American Society of Internal Medicine American Medical Association , and American Thoracic Society Editor(s): Bryan L Martin, DO

8. Microscopic Polyangiitis microscopic polyangiitis Microscopic Polyarteritis. Hypersensitivity Vasculitis.Leukocytoclastic Vasculitis. Book, Home Page. http://www.fpnotebook.com/RHE13.htm

Home About Links Index ... Editor's Choice Paid Advertisement (click above). Please see the privacy statement Rheumatology Cardiovascular Medicine Assorted Pages Thromboangiitis Obliterans Vasculitis Small Vessel Vasculitis Microscopic Polyangiitis Microscopic Polyangiitis Microscopic Polyarteritis Hypersensitivity Vasculitis Leukocytoclastic Vasculitis Book Home Page Cardiovascular Medicine Dental Dermatology Emergency Medicine Endocrinology Gastroenterology General Medicine Geriatric Medicine Gynecology Hematology and Oncology HIV Infectious Disease Jokes Laboratory Neonatology Nephrology Neurology Obstetrics Ophthalmology Orthopedics Otolaryngology Pediatrics Pharmacology Prevention Psychiatry Pulmonology Radiology Rheumatology Sports Medicine Surgery Urology Chapter Rheumatology Index Bone Cardiovascular Medicine Diffuse Examination Infectious Disease Intra-Articular Disorders Laboratory General Marfans Myofascial Neurology Osteoarthritis Pain Pediatrics Pharmacology Procedure Radiology RA Spondylitis Symptom Evaluation Page Cardiovascular Medicine Index Environ Raynauds Thromboangiitis Obliterans Vasculitis Vasculitis Small Vasculitis Small Polyangiitis See Also Small Vessel Vasculitis Epidemiology Most common ANCA -associated Small Vessel Vasculitis Age of onset peaks at 40 to 60 years Gender: Men more commonly affected Symptoms Fever Arthralgias and Myalgias Cough ( Hemoptysis may be present) Signs Renal involvement most common ( Glomerulonephritis Palpable Purpura Lung disease (pulmonary hemorrhage) Differential Diagnosis Polyarteritis Nodosa ANCA -associated

9. Small Vessel Vasculitis Children HenochSchonlein Purpura. Type ANCA-associated small-vesselVasculitis Non-Granulomatous Disease microscopic polyangiitis http://www.fpnotebook.com/RHE12.htm

Home About Links Index ... Editor's Choice Paid Advertisement (click above). Please see the privacy statement Rheumatology Cardiovascular Medicine Assorted Pages Thromboangiitis Obliterans Vasculitis Small Vessel Vasculitis Microscopic Polyangiitis Small Vessel Vasculitis Vasculitis of Small Vessels Antineutrophil Cytoplasmic Antibody Vasculitis ANCA-Associated Vasculitis Book Home Page Cardiovascular Medicine Dental Dermatology Emergency Medicine Endocrinology Gastroenterology General Medicine Geriatric Medicine Gynecology Hematology and Oncology HIV Infectious Disease Jokes Laboratory Neonatology Nephrology Neurology Obstetrics Ophthalmology Orthopedics Otolaryngology Pediatrics Pharmacology Prevention Psychiatry Pulmonology Radiology Rheumatology Sports Medicine Surgery Urology Chapter Rheumatology Index Bone Cardiovascular Medicine Diffuse Examination Infectious Disease Intra-Articular Disorders Laboratory General Marfans Myofascial Neurology Osteoarthritis Pain Pediatrics Pharmacology Procedure Radiology RA Spondylitis Symptom Evaluation Page Cardiovascular Medicine Index Environ Raynauds Thromboangiitis Obliterans Vasculitis Vasculitis Small Vasculitis Small Polyangiitis See Also Vasculitis Epidemiology: Most common small vessel Vasculitis Older Adults: ANCA -associated small vessel Vasculitis Children: Henoch-Schonlein Purpura Type: ANCA -associated small-vessel Vasculitis Non-Granulomatous Disease Microscopic Polyangiitis Most common ANCA Vasculitis Lung and renal findings Drug-Induced Vasculitis (7-21 days after drug onset) Penicillin and Aminopenicillins Sulfonamide s

10. Microscopic Polyangiitis Rheumatology Cardiovascular Medicine Vasculitis Small Polyangiitis microscopic polyangiitis. microscopic polyangiitis. Microscopic Polyarteritis. Hypersensitivity Vasculitis http://www.aroundcharlotte.com/RHE13.htm

Home About Links Index ... Editor's Choice Paid Advertisement (click above). Please see the privacy statement Rheumatology Cardiovascular Medicine Assorted Pages Thromboangiitis Obliterans Vasculitis Small Vessel Vasculitis Microscopic Polyangiitis Microscopic Polyangiitis Microscopic Polyarteritis Hypersensitivity Vasculitis Leukocytoclastic Vasculitis Book Home Page Cardiovascular Medicine Dental Dermatology Emergency Medicine Endocrinology Gastroenterology General Medicine Geriatric Medicine Gynecology Hematology and Oncology HIV Infectious Disease Jokes Laboratory Neonatology Nephrology Neurology Obstetrics Ophthalmology Orthopedics Otolaryngology Pediatrics Pharmacology Prevention Psychiatry Pulmonology Radiology Rheumatology Sports Medicine Surgery Urology Chapter Rheumatology Index Bone Cardiovascular Medicine Diffuse Examination Infectious Disease Intra-Articular Disorders Laboratory General Marfans Myofascial Neurology Osteoarthritis Pain Pediatrics Pharmacology Procedure Radiology RA Spondylitis Symptom Evaluation Page Cardiovascular Medicine Index Environ Raynauds Thromboangiitis Obliterans Vasculitis Vasculitis Small Vasculitis Small Polyangiitis See Also Small Vessel Vasculitis Epidemiology Most common ANCA -associated Small Vessel Vasculitis Age of onset peaks at 40 to 60 years Gender: Men more commonly affected Symptoms Fever Arthralgias and Myalgias Cough ( Hemoptysis may be present) Signs Renal involvement most common ( Glomerulonephritis Palpable Purpura Lung disease (pulmonary hemorrhage) Differential Diagnosis Polyarteritis Nodosa ANCA -associated

11. Johns Hopkins Vasculitis Center Discusses Microscopic Polyangiitis, A Type Of Va More information is coming soon. Pictured below is a biopsy of the gastrocnemiusmuscle, performed in a 69 year–old man with microscopic polyangiitis. http://vasculitis.med.jhu.edu/typesof/polyangiitis.html

More information is coming soon. Pictured below (top of page) All information contained within the Johns Hopkins Vasculitis Center website is intended for educational purposes only. Visitors are encouraged to consult other sources and confirm the information contained within this site. Consumers should never disregard medical advice or delay in seeking it because of something they may have read on this website.

12. Re: Microscopic Polyangiitis The Health Beat covers Top Health Medical Internet Web Sites, microscopic polyangiitis, Health Organizations, Health News, Medical Associations, Pharmaceutical Companies, Government Health Sites. Site Support and information for people fighting microscopic polyangiitis. Frequently asked questions and dealing http://www.mtio.com/lupus/docmess/2966.html

Re: microscopic polyangiitis Posted by LupusDoc on March 28, 1998 at 13:24:31: Hello Darcy! We asked the doctor your questions, and this was his reply: I'll give you a brief run-down on Microscopic polyangiitis. But I'm sure it's no more than what you already know. Microscopic polyangiitis is actually a new term (since 1992)for a variant form of Polyarteritis Nodosa (PAN). These are systemic necrotizing vasculitis. They can cause severe damage to blood vessels throughout the body. In Microscopic polyangiitis, the vessels most often affected are the very small ones (capillaries, venules and arterioles). When the vessels affected are in organ systems (which they often are), it can cause severe, sometimes irreversible damage to the organ. Diagnosis of Microscopic polyangiitis depends on biopsy findings. Untreated , the 5-year survival rate for Microscopic polyangiitis is only about 13%. But with adequate treatment (which can include high-dose steroids, and cyclophosphamide) that rate rises to more that 50%. There is also the possibility that some of the new AIDS and Cancer drugs being used, may be benenficial in the treatment of PAN or Microscopic polyangiitis. I know this information doesn't sound postive, but it really is, considering that in my career as a physicianwhen I started, PAN was considered to have about a 3-5% 5-year survival rate, with treatment. So it's getting better, quickly.

13. Johns Hopkins Vasculitis Center Discusses Types Of Vasculitis Affects people over the age of 50. microscopic polyangiitis A systemicvasculitis affecting small and medium–sized blood vessels. http://vasculitis.med.jhu.edu/typesof/typesof.html

Angiitis Arteritis vasculitides There are many different types of diseases that belong to this category. Although the diseases are similar in some ways, they often differ with respect to which organs are affected, which medications are used to treat them, and other characteristics. Behcet's Disease Characterized by the triad of mouth ulcers, genital ulcers, and eye inflammation, but can affect different organ systems. Buerger's Disease Mainly affects smokers, leading to decreased blood flow to the hands and feet. Central Nervous System Vasculitis Very rare disease that may involve the brain and spinal cord. Cryoglobulinemia Characterized by recurrent purpura on the lower extremities, and often associated with hepatitis C virus infections. Giant Cell Arteritis The most common type of vasculitis. Affects people over the age of 50. Microscopic Polyangiitis Polyarteritis Nodosa Polymyalgia Rheumatica A syndrome of pain and stiffness localized to the shoulders and hips. Often occurs in association with Giant Cell Arteritis. Rheumatoid Vasculitis A vasculitis that sometimes complicates the course of rheumatoid arthritis (RA). Usually occurs in patients with a history of severe RA.

14. Treatment Of Polyarteritis Nodosa And Microscopic Polyangiitis. Treatment of polyarteritis nodosa and microscopic polyangiitis. GuillevinL, Lhote F. Hopital Avicenne, Universite ParisNord, Bobigny, France. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9

15. ORPHANET® : Microscopic Polyangiitis Translate this page ORPHANET. ORPHANET database access. microscopic polyangiitis.Direct access to details Alias Home Page. http://www.orpha.net/static/GB/microscopic_polyangiitis.html

ORPHANET database access Microscopic polyangiitis Direct access to details Alias : Home Page

16. Error Page DISEASE microscopic polyangiitis, microscopic polyangiitis (MPA) refersto a necrotizing systemic vasculitis with few or no immune http://www.orpha.net/consor/cgi-bin/OC_Exp.php?Lng=GB&Expert=727

17. Microscopic Polyangiitis microscopic polyangiitis. Table 2 Features that allow differentiation of microscopicpolyangiitis from several other forms of smallvessel vasculitis, http://orphanet.infobiogen.fr/data/patho/GB/uk-MPA.html

Microscopic polyangiitis Author: Professor J. Charles Jennette Creation date: October 2002 Disease name Microscopic polyangiitis (MPA) Microscopic polyarteritis Microscopic polyangiitis is a more appropriate name than microscopic polyarteritis because some patients show no evidence for arterial involvement. Definition Classification of systemic vasculitis Vasculitis is an inflammation of vessel walls. It has many causes, although they result in only a few histological patterns of vascular inflammation. Small-vessel vasculitis is defined as a vasculitis affecting vessels smaller than arteries, such as arterioles, venules and capillaries. There is no widely accepted classification of primary vasculitis, although a working framework has been provided by a consensus reached by the leading investigators at a meeting in Chapel Hill, North Carolina in 1995. Systemic vasculitides form a heterogeneous group of vascular inflammatory diseases that can be sub-divided on the basis of the underlying histopathology, the type of vessels involved, the target organs involved, and the resulting clinical picture (table 1). Table 1: The Chapel Hill Consensus Conference on the Nomenclature of Systemic Vasculitis Large Vessel Vasculitis Giant-cell arteritis – granulomatous arteritis of the aorta and its major branches, especially the extracranial branches of the carotid artery; usually in patients over 50 years old and associated with polymyalgia rheumatica.

18. Microscopic Polyangiitis Information Page Diseases Database microscopic polyangiitis Information Page. 2 synonyms or equivalents werefound. microscopic polyangiitis aka/or Microscopic polyarteritis http://www.diseasesdatabase.com/sieve/item1.asp?glngUserChoice=8193

19. Diseases Database Disease, Symptom, Sign, Etc Alphabetical Index : M Diseases Da colitis Microscopic cystic corneal dystrophy see CoganGuerry map-dot-fingerprintcorneal dystrophy microscopic polyangiitis Microscopic polyarteritis see http://www.diseasesdatabase.com/sieve/disease_index_m.asp

Diseases Database [Previous page] [Search] [Index] [Feedback] Diseases Database disease, symptom, sign, etc alphabetical index : M Machado-Joseph Azorean disease Machupo virus see Bolivian hemorrhagic fever MacLeod's syndrome Macro-orchidism see Testicular enlargement Macroamylasaemia Macrocephaly see Megencephaly Macrocytic red blood cell see Macrocytosis (erythrocyte) Macrocytosis (erythrocyte) Macroglossia Macrogyria see Pachygyria Macrolides Macromastia see Breast hypertrophy Macroorchidism see Testicular enlargement Macrophage migration inhibitory factor Macrosomia Macrostomia ... Macrothrombocytosis Macular atrophy, Jadassohn type see Anetoderma Macular atrophy, Schweninger-Buzzi type see Anetoderma Macular hole Macular pucker see Epiretinal membrane Macular star see Hard retinal exudate Maculopapular rash Maculopathy Maculopathy, age related see Senile macular retinal degeneration Madelung's deformity Madura foot see Mycetoma Madurella mycetomi Mafenide Maffucci syndrome see Dyschondroplasia Magnesium hydroxide Magnesium levels low (plasma or serum) see Hypomagnesemia Magnesium levels raised (plasma or serum) see Hypermagnesaemia Magnesium oxide Magnesium salts Magnesium sulfate Maidenhair tree see Gingko biloba Majewski syndrome see Short rib-polydactyly syndrome type 2 Major histocompatibility complex class I deficiency Major tranquilizers see Antipsychotic agents Malabsorption syndrome Maladie de Roger Malakoplakia ... Malathion Malattia leventinese see Doyne's honeycomb choroiditis Malayan filariasis see Brugia malayi Male > Female see Incidence in males greater than females Male infertility Male pattern baldness Male pseudohermaphroditism

20. BioMed Central | Abstract | Polyarteritis Nodosa And Microscopic Polyangiitis: E Report Polyarteritis Nodosa and microscopic polyangiitis Etiologic and DiagnosticConsiderations Laura B Hughes MD, and SLouis Bridges Jr MD, PhD Division of http://www.biomedcentral.com/1523-3774/4/75/abstract

Welcome guest user home journals A-Z journals by subject advanced search ... Issue 1 Viewing options Abstract Full text PDF Other links: E-mail to a friend Download references Post a comment Search PubMed For Hughes LB Bridges Jr SL Report Polyarteritis Nodosa and Microscopic Polyangiitis: Etiologic and Diagnostic Considerations Laura B Hughes MD, and SLouis Bridges Jr MD, PhD Division of Clinical Immunology and Rheumatology, 415 Lyons-Harrison Research Building, University of Alabama at Birmingham, Birmingham, AL, 35294-0007, USA. Current Rheumatology Reports Abstract Polyarteritis nodosa (PAN) is a systemic necrotizing vasculitis of medium-sized vessels with clinical manifestations resulting from ischemia and infarction of affected tissues and organs. Although the cause of most cases of PAN and the related disorder microscopic polyangiitis (MPA) remains largely unknown, there has been significant progress in understanding the pathogenesis of vascular inflammation. The diagnostic approach to PAN and MPA should be individualized and based on specific organ involvement. Because no test or clinical finding reliably indicates the presence or absence of PAN or MPA, diagnosis requires integration of clinical findings, angiography, and biopsy data. Terms and Conditions Privacy statement Information for advertisers Contact us

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