21. Infectious Diseases - Infectious Mononucleosis (EBV) Infectious Diseases. INFECTIOUS mononucleosis. The development ofinfectious mononucleosis in a laboratory worker was observed to http://www.mc.vanderbilt.edu/peds/pidl/infect/ebv.htm

PIDL Home/ Contents Development Nutrition Acute Illness ... Psychosocial Infectious Diseases INFECTIOUS MONONUCLEOSIS The development of infectious mononucleosis in a laboratory worker was observed to be associated with the development of serologic reactivity to Epstein- Barr virus antigens and led to studies demonstrating that infectious mononucleosis was uniformly associated with seroconversion to EBV antigens, establishing EBV as the cause of this long mysterious illness. Shortly thereafter, it was demonstrated that EBV has the capacity to transform or immortalize human B lymphocytes, allowing the derivation of EBV transformed B lymphoblastoid cell lines that can be propagated indefinitely. Morphologically, the EBV is a typical enveloped herpes virus, with the nucleocapsid having icosahedral symmetry. The nucleoid core contains a double stranded linear DNA genome. The EBV virion preferentially infects and transforms B lymphocytes. The various components of the immune response to EBV infection appear to be largely responsible for the protean clinical manifestations. After an incubation period of 2- 7 weeks, adolescents or young adults developing infectious mononucleosis have as many as 20% of their circulating B lymphocytes infected with EBV. There is a brisk cellular immune response composed of natural killer cells, cytotoxic T cells, and antibody dependent cellular cytotoxicity.

22. Mononucleosis Fact Sheet mononucleosis Fact Sheet. PDF Version for this Fact Sheet. Infectiousmononucleosis ( mono ) is caused by a virus. The Epstein http://edcp.org/html/mono.html

EDCP Mission/Vision General Information on Bioterrorism Bioterrorism Information for Health Care Provide rs ... ImmuNet Mononucleosis Fact Sheet This page has moved. You will be redirected to the new location in 5 seconds or you can click on the link below: http://www.edcp.org/factsheets/mono.html Back Top Print Version Links marked with are PDF. Download Adobe Acrobat Reader for viewing .pdf files View this page in German Spanish French Italian Portuguese Family Health Administration Home Site Map Factsheet Index ... Site Use Policies To address technical problems or make suggestions regarding this site send email to: webmaster@dhmh.state.md.us CommunityHealth Administration Last Modified 02/20/2003 10:03:07 AM

23. The Physician And Sportsmedicine: Infectious Mononucleosis Infectious mononucleosis Recognizing the Condition, 'Reactivating' the Patient. Table1. Uncommon or Rare Complications of Infectious mononucleosis. http://www.physsportsmed.com/issues/1996/04_96/eichner.htm

Infectious Mononucleosis: Recognizing the Condition, 'Reactivating' the Patient E. Randy Eichner, MD THE PHYSICIAN AND SPORTSMEDICINE - VOL 24 - NO. 4 - APRIL 96 In Brief: A two-step infection by the Epstein-Barr virus accounts for the characteristic features of infectious mononucleosis (IM). New serologic tests for viral antigens exist, but a rapid kit test for heterophil antibody usually suffices to confirm the diagnosis. General management is supportive only. Splenic rupture is very rare, almost never fatal if diagnosed early, and, in most cases, is probably best treated by splenectomy. Athletes tend to recover from IM faster than nonathletes. When the spleen returns to normal size, the athlete can return to contact sports, though it may take 3 to 6 months for an elite athlete to regain top form. I nfectious mononucleosis (IM) can pose headaches for physicians who treat young athletes and other physically active young people. The condition, whose prevalence peaks in about the same age range as athletic activity, is sometimes difficult to diagnose. Further, the risk of splenic rupture may complicate decisions about when athletes may safely return to play, especially in view of the lack of consensus on that issue. Two-Stage Pathogenesis IM is caused by the Epstein-Barr virus (EBV). EBV is a herpesvirus that, like other herpesviruses (herpes simplex, varicella-zoster, cytomegalovirus), imparts a two-step pathogenesis. First, EBV infects epithelial cells and propagates, causing cytolysis and shedding progeny. The progeny then invade a secondary cell type, where they remain latent and so establish a persistent infection.

24. MONONUCLEOSIS INFECCIOSA Translate this page Servicio producido por Sarenet Información mantenida por Pulso100. Patrocinadopor Sanitas. mononucleosis INFECCIOSA. ES GRAVE LA mononucleosis? http://www.ecomedic.com/em/monuinfe.htm

window.location.href="http://www.tuotromedico.com/temas/mononucleosis.htm"; Servicio producido por Sarenet . Patrocinado por Sanitas M ONONUCLEOSIS I NFECCIOSA Signos Gravedad Tratamiento OTROS NOMBRES Enfermedad del beso . SIGNOS Y SINTOMAS Fiebre. Molestias de garganta. Fatiga. Astenia. Dolores musculares. INFORMACION GENERAL DIAGNOSTICO GRAVE LA MONONUCLEOSIS? TRATAMIENTO

25. Mononucleosis What every pediatrician should know about Infectious mononucleosis Infectiousmononucleosis was first recognized in 1920, but the etiology was elusive. http://home.coqui.net/myrna/mono.htm

What every pediatrician should know about Infectious Mononucleosis CLINICAL MANIFESTATIONS. COMPLICATIONS. DIAGNOSIS. TREATMENT. Back to PB Index Back to PB Homepage

26. Mononucleosis http://www.infecto.edu.uy/espanol/revisiontemas/tema6/mononucleosis.html

Cursos Otros Sitios Preguntas Frecuentes (FAQ) Novedades ... Home Sindrome Mononucleosido, Autora: Prof. Ag. Dra. Teresa Lopez Facultad de Medicina, Montevideo, Uruguay MONONUCLEOSIS INFECCIOSA Complicaciones Tratamiento 1) El virus del Epstein Barr 2) El virus de inmunodeficiencia humana 3) El citomegalovirus Toxoplasma gondii puede causar adenomegalias y linfomonocitos. 5) El virus de la rubeola produce fiebre, faringitis, exantema, adenomegalias en las regiones retroauricular y espinal posterior y linfocitosis. 6) Las hepatitis virales 7) La linfomonocitosis infecciosa aguda adenovirus, virus Urleano, virus del herpesvirus humano 6, Brucella spp etc. 9) Entre las causas no infecciosas MONONUCLEOSIS INFECCIOSA El VEB pertenece a la familia Herpesviridae Dolor de garganta 82% Malestar febril 57% Fiebre 76% Cefalea 51% Anorexia 21% Mialgias 20% Dolor abdominal 9% Tos 5% Artralgias 2% Signos Adenomegalia 94% Faringitis 84% Fiebre 76% Esplenomegalia 52% Hepatomegalia 12% Enantema palatino 11% Ictericia 9% Exantema 10% Complicaciones En raras ocasiones se producen complicaciones.

27. Symptoms Of Mononucleosis The symptoms of mononucleosis include sore throat, fatigue, enlarged lymph nodes,and nausea. Learn more about this virus. Symptoms of mononucleosis. http://www.allsands.com/Health/Diseases/symptomsofmono_btg_gn.htm

Symptoms of mononucleosis Mononucleosis is technically called infectious mononucleosis or glandular fever, but is generally referred to as "mono" for short. It occurs primarily between the ages of 10 and 35 years old. When younger children are infected, it causes little or no illness. Such exposure does, however, create an immunity to the disease. Nearly 90% of Americans have antibodies for mononucleosis by age 40. Mono has an incubation period of 30 to 40 days and the symptoms usually last 7 to 14 days but can last for several weeks. The virus can stay alive within the body for several months. The name mononucleosis comes from the fact that the disease distorts the white blood cells, causing them to only have one nucleus. Only a blood test called the mononucleosis spot test can determine if someone has the disease. SYMPTOMS OF MONONUCLEOSIS bodyOffer(7530) The following symptoms can be present with mono, but most likely not all will be. Sore throat, usually red Enlarged lymph nodes in all parts of the body Fever Nausea Loss of appetite Extreme fatigue Enlarged spleen (2/3 of mono patients) Ulceration of the pharynx (sometimes) Swelling of the upper eyelid Trouble breathing Rapid heart beat Red rash on the body (about 15% of mono patients) Oversensitivity to light CAUSES Mononucleosis is thought to be caused by the Epstein-Barr (EB) virus in 9 out of 10 cases. It is transmitted primarily through oral contact which is why it is often referred to as "the kissing disease." It can also be spread by coughing, sneezing, or sharing drinks.

28. Infectious Mononucleosis Infectious mononucleosis up. mononucleosis, A short document aboutmononucleosis mononucleosis fact sheet, This short document is a http://omni.ac.uk/browse/mesh/detail/C0021345L0021345.html

Infectious Mononucleosis [up] Related topics: broader Epstein-Barr Virus Infections other Agammaglobulinemia Burkitt Lymphoma Eosinophilia Leukemia, Hairy Cell ... Mononucleosis A short document about mononucleosis (an infection caused by the Epstein-Barr virus, also called glandular fever), aimed at patients and families. It covers symtoms, diagnosis, complications, treatment etc. Published by the American Academy of Family Physicians (AAFP). Infectious Mononucleosis Patient Education Mononucleosis fact sheet This short document is a patient information fact sheet provided by the Epidemiology and Disease Control Program for the State of Maryland Department of Health and Mental Hygiene. It includes information on the cause, symptoms and prevention of infectious mononucleosis. Herpesvirus 4, Human Infectious Mononucleosis Patient Education Last modified 28/Mar/2003 [Low Graphics]

29. Mono Infectious mononucleosis (Mono). What is mononucleosis and What Causes It? Thecause of mononucleosis has been traced to the EpsteinBarr (EB) virus. http://www.ualberta.ca/HEALTHINFO/mono.htm

Home Healthy Student Software Interactive Sexual Decision Making Site Health Information ... Send Us Your Comments Infectious Mononucleosis (Mono) What is Mononucleosis and What Causes It? "Mono" is a mild self-limiting illness and, in most cases, does not deserve its notorious reputation. It usually runs its course quickly and rarely produces any serious complications. One can expect complete return to normal health following mono. It has been estimated that approximately 50 percent of students have had mono by the time they enroll in college. Many times the symptoms are so mild it is not even recognized. The cause of mononucleosis has been traced to the Epstein-Barr (EB) virus. There are, however, other viruses that may produce a mono-like illness. Who Gets Mono? Mononucleosis is an illness that affects teenagers and young adults, mainly ages 14 to 30. It can occur in children and older adults. What are the Symptoms?

30. MedWebPlus Subject Infectious Mononucleosis Infectious mononucleosis Broader Terms Web Sites A, , GO, adam.com EncyclopediaDisease Reference Infectious mononucleosis (EB) (Iowa Clinic). http://www.medwebplus.com/subject/Infectious_Mononucleosis

Main About MWP Contribute to MWP Contact Us A service of Flexis, Inc. Welcome to MedWebPlus 2.3! A free service to help you find health sciences information quickly and easily. Infectious Mononucleosis Broader Terms: All Diseases Epstein-Barr Virus Infections Hematologic Diseases Immunologic Diseases ... Virus Diseases Web Sites: A GO adam.com Encyclopedia Disease Reference Infectious mononucleosis (EB) (Iowa Clinic) A GO American Academy of Family Physicians Information for Patients Getting through Mononucleosis A GO Centers for Disease Control and Prevention. National Center for Infectious Diseases. Epstein-Barr Virus and Infectious Mononucleosis A GO KidsHealth.org for teens Solving the Mystery of Mononucleosis A GO Maryland Department of Health and Mental Hygiene. Epidemiology and Disease Control Program Mononucleosis Fact Sheet A GO University of Pittsburgh Department of Pathology Case Archive Case 37 - Lymphadenopathy by Lisa J .Kohler and Charles A. Richert. August 1995 Flexis, Inc. Privacy statement Powered by y-Base

31. Mononucleosis mononucleosis mononucleosis is not a bad word, and it's not necessarilya bad diagnosis to receive. Infectious mononucleosis is http://www.colby.edu/health.serv/health_matters/mono.html

Mononucleosis Mononucleosis is not a bad word, and it's not necessarily a bad diagnosis to receive. Infectious mononucleosis is caused by the Epstein Barr virus and can produce a spectrum of clinical symptoms. Mono is common in the 16-24-year-old age range, especially in colleges or the military where close living quarters are common. Eighty percent of people who have infectious mono will have a viral-like syndrome, frequently with sore throat, fever, headache, fatigue, and swollen lymph nodes in the neck. In the belief that they have a cold, many of these people will not seek medical attention and, thus, will have mono that goes undiagnosed. In fact, the vast majority of people over 40 years old test positive (using a special test) for having had mono sometime in their life; many of these people never knew they were infected. Mono gets a bad rap because of the complications that 20 percent of people may experience. Complications may include such severe swollen glands in the neck that breathing or eating is compromised. Mono can also affect the lining around the brain, producing an encephalitis-like picture. Mono can inflame the liver, producing a hepatitis. The spleen can become enlarged. Because of the tight capsule around the spleen, enlargement can produce pain and the danger of rupturing, even with minor trauma. (If you had an enlarged spleen with your mono infection you would be asked to refrain from contact sports.) Mono has also been associated with fatigue varying from a few weeks to a few months. Mono gets its bad reputation because people with severe complications of mono get more notoriety.

32. Chlamydia Trachomatis mononucleosis EpsteinBarr Virus. EBV. Epstein Barr Virus. Book, HomePage. http://www.fpnotebook.com/ID179.htm

Home About Links Index ... Editor's Choice Paid Advertisement (click above). Please see the privacy statement Infectious Disease Sexually Transmitted Disease Bacteria ... Chancroid Chlamydia trachomatis Lymphogranuloma venereum Neisseria gonorrhoeae Syphilis Syphilitic paresis ... Genital Herpes Assorted Pages Sexually Transmitted Disease Dermatology Sexually Transmitted Disease Parasites Genital Ulcer ... Gonococcal Arthritis Chlamydia trachomatis Chlamydia Book Home Page Cardiovascular Medicine Dental Dermatology Emergency Medicine Endocrinology Gastroenterology General Medicine Geriatric Medicine Gynecology Hematology and Oncology HIV Infectious Disease Jokes Laboratory Neonatology Nephrology Neurology Obstetrics Ophthalmology Orthopedics Otolaryngology Pediatrics Pharmacology Prevention Psychiatry Pulmonology Radiology Rheumatology Sports Medicine Surgery Urology Chapter Infectious Disease Index Bacteria Dermatology Emerging Examination Ophthalmology Fever Fungus Gastroenterology Helminth Immunization Laboratory General Neurology Obstetrics Parasite Pediatrics Pharmacology Prevention Prion Procedure Rheumatology Sexually Transmitted Disease Surgery Travel Medicine Vector Virus Page Sexually Transmitted Disease Index Approach Bacteria Chancroid Bacteria Chlamydia Bacteria Chlamydia Lymphogranuloma Venereum Bacteria Gonorrhea Bacteria Syphilis Bacteria Syphilis Dementia Bacteria Syphilis Jarisch-Herxheimer Bacteria Ureaplasma Virus HSV II Epidemiology: Very Prevalent Asymptomatic teenage female test positive: 5-10% Sexually active persons: 10%

33. Hardin MD : Mononucleosis / Glandular Fever From the University of Iowa, the *best* lists of Internet sources in /HEAD infectiousmononucleosis glandular fever. mononucleosis / Glandular Fever. http://www.lib.uiowa.edu/hardin/md/mononucleosis.html

Mononucleosis / Glandular Fever "We list the best sites that list the sites" Site Map Diseases Home Free journals ... Diseases Search Hardin MD See also: Home Virus Diseases Family Health All links on this page hand-checked Popular Women's Health Dermatology Nursing Pharm Infect Disease AIDS / HIV +Pictures Bronchitis +Pictures Cold +Pictures Ear Infection +Pictures Endometriosis +Pictures Flu +Pictures Infectious Diseases +Pictures Medical Pictures Scarlet Fever +Pictures STD's Pictures Sinus Infection +Pictures Skin Pictures Strep Throat +Pictures Tonsils +Pictures Virus Diseases A Hardin MD Focus Page MEDLINE plus Infectious mononucleosis Symptoms / Diagnosis National Library of Medicine LookSmart : Infectious mononucleosis or glandular fever Open Directory Project : Health : ... : Mononucleosis (Other versions: Google AOL MedWebPlus : Infectious mononucleosis Steve Foote and Andy Kogelnik, y-DNA,inc, Atlanta, Georgia Mononucleosis US Government Yahoo : Mononucleosis Infectious mononucleosis Harlan R. Weinberg, Snow Tiger Medical Systems, Inc, Stamford, Connecticut OMNI : Infectious mononucleosis Univ Nottingham, United Kingdom

34. Self Care Information: Mononucleosis mononucleosis What Is Mono And What Causes It? mononucleosis is anillness caused by infection with a virus. The EpsteinBarr Virus http://www.uhs.wisc.edu/ex/selfcare/resource/mononucleosis.php

Mononucleosis What is Mono and What Causes It? Who Gets Mono? What are the Symptoms? How is Mono Diagnosed? ... What about Chronic EBV Syndrome? What Is Mono And What Causes It? Mononucleosis is an illness caused by infection with a virus. The Epstein-Barr Virus (EBV) is the usual cause of infectious mono. Infection with other viruses, like the cytomegalovirus (CMV) can also produce a mono-like illness. Who Gets Mono? Mono is an illness mainly of adolescents and young adults. In developed nations, the majority of the population has been exposed to the Epstein-Barr virus by the age 18. This means many of us have had infections as children caused by the mono virus (which were asymptomatic or mild) and we are immune to re-infection. What Are The Symptoms? Students most often experience a painful sore throat with tonsillar enlargement. Mono will also typically cause fever, headache, fatigue and enlarged lymph nodes ("swollen glands") in the neck. Less often you can experience loss of appetite, nausea, vomiting, diarrhea or measles-like rash. The development of a rash can also be seen in greater than 80% of patients who have mono and are prescribed the antibiotic "amoxicillin." How Is Mono Diagnosed?

35. Infectious Mononucleosis - Health Information Health information discussing infectious mononucleosis, which is a common acuteinfectious disease usually found in individuals between the ages of 5 and 30. http://www.mckinley.uiuc.edu/health-info/dis-cond/commdis/inf-mono.html

Infectious Mononucleosis Infectious mononucleosis (mono) is a common acute infectious disease usually found in individuals between the ages of 5 and 30. It is caused by the Epstein-Barr virus. SIGNS Early signs or symptoms of mono can be vague, such as headache, chills, easy fatigability, fever and sore throat. As the disease advances, its manifestations become more obvious; fever; feeling of extreme exhaustion; tender, enlarged lymph nodes in the neck, armpits and groin. Symptoms of nausea, vomiting, decreased appetite and abdominal pain may appear. There may be yellowing of the skin or whites of the eyes (jaundice). You may have any or all of the above signs or symptoms. DIAGNOSIS Diagnosis is confirmed by a blood test. These tests may not be positive until several weeks after the symptoms arise and, rarely, may remain negative throughout the course of the disease. TREATMENT Since the disease is viral, there is no medication that can cure mono. Treatment is symptomatic and supportive, but medical supervision is absolutely necessary. Patients are instructed to: Obtain 10-12 hours of sleep a day.

36. Medic-Planet Mononucleosis mononucleosis See also Fatigue, Fever, Lymphocytes, Phagocytes and otherleukocytes, Spleen, Viruses and disease, Back to the Index page http://www.medic-planet.com/MP_article/internal_reference/mononucleosis

37. Medic-Planet Mononucleosis mononucleosis See also Fatigue, Fever, Lymphocytes, Phagocytes and otherleukocytes, Spleen, Viruses and disease, Back to the Index page http://www.medic-planet.com/MP_article/internal_reference/Mononucleosis

38. Children's Health At Doernbecher - Child Health A-Z Infectious mononucleosis, The EpsteinBarr virus The Epstein-Barr virus (EBV)may cause infectious mononucleosis in adolescents and young adults. http://www.ohsuhealth.com/dch/health/adolescent/mono.asp

Adolescent Medicine Index Adolescent Growth and Development Cognitive Development Relationship Development ... Online Resources You have selected the following Health topic: - Adolescent Medicine - Burns - Cardiovascular Disorders - Care of the Terminally Ill Child - Children Having Surgery - Common Childhood Injuries and Poisoning - Craniofacial Anomalies - Dermatology - Diabetes - Eye Care - Genetics - Growth and Development - High-Risk Newborn - High-Risk Pregnancy - Immunizations - Infectious Diseases - Mental Health - Neurological Disorders - Normal Newborn - Oncology - Orthopaedics - The Pediatrician - Pregnancy and Childbirth - Respiratory Disorders - Transplantations - Well-Care Visits Infectious Mononucleosis RELATED SERVICES General Pediatrics Family Medicine Infectious Diseases The Epstein-Barr virus: The Epstein-Barr virus (EBV) may cause infectious mononucleosis in adolescents and young adults. However, even after the symptoms of infectious mononucleosis have disappeared, the EBV will remain dormant in the person. The virus can reactivate periodically, however, usually without symptoms. What is infectious mononucleosis?

39. Page Moved - Infectious Mononucleosis Infectious mononucleosis, (mono, EBV mononucleosis). What is infectiousmononucleosis? /Infectious mononucleosis is a viral disease http://www.health.state.ny.us/nysdoh/consumer/infect.htm

location.href="/nysdoh/communicable_diseases/en/infect.htm"; Page moved click here if your browser does not forward you to the new page. http://www.health.state.ny.us/nysdoh/communicable_diseases/en/infect.htm

40. Postgraduate Medicine: Infectious Mononucleosis Infectious mononucleosis. Complexities of a common syndrome. Stephen E. Godshall,MD; Jeffrey T. Kirchner, DO. Infectious mononucleosis in older adults. http://www.postgradmed.com/issues/2000/06_00/godshall.htm

Infectious mononucleosis Complexities of a common syndrome Stephen E. Godshall, MD; Jeffrey T. Kirchner, DO VOL 107 / NO 7 / JUNE 2000 / POSTGRADUATE MEDICINE CME learning objectives To become familiar with the causes and epidemiologic characteristics of infectious mononucleosis To recognize the clinical and laboratory abnormalities seen with infectious mononucleosis To be aware of potential complications of infectious mononucleosis and how to manage them This page is best viewed with a browser that supports tables Preview : Although infectious mononucleosis is usually caused by Epstein-Barr virus, as many as one in five casespossibly moremay be due to a different infectious agent. Drs Godshall and Kirchner discuss the complexities of this common syndrome and offer useful tips on diagnosis and management. Godshall SE, Kirchner JT. Infectious mononucleosis: complexities of a common syndrome Postgrad Med 107(7):175-86 T he syndrome of fever, pharyngitis, and lymphadenopathy was first described in the medical literature in the 1880s (1), but the term "infectious mononucleosis" did not come into use until the 1920s. In 1932, heterophil antibodies were identified in patients with clinical infectious mononucleosis. In the 1950s, Epstein, Barr and Achong discovered that a herpesvirus was present in all tissue samples of Burkitt's lymphoma from Africa. The development of an indirect immunofluorescence assay for Epstein-Barr virus (EBV) a decade later led to epidemiologic studies that showed antibodies to EBV to be present in more than 90% of adults in the United States (1). It was not until the late 1960s, when an unfortunate laboratory technician acquired infectious mononucleosis while working with EBV and serologically converted to EBV-positive status, that the link between EBV and infectious mononucleosis was discovered (2).

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