1. Muscular Dystrophies/Myopathies muscular dystrophies and Myopathies. Myopathies are diseases of themuscles. They can be caused by an inherited genetic abnormality http://ucneurology.uchicago.edu/Neurological_Disorders/NeuroMuscular/Muscular_Dy

Muscular Dystrophies and Myopathies Myopathies are diseases of the muscles. They can be caused by an inherited genetic abnormality (as in muscular dystrophy) or an abnormality of the immune system (such as polymyositis). These disorders can develop at any time from birth through adulthood. University of Chicago neurologists have expertise in treating many different muscle diseases. There are many types of muscular dystrophy (MD). These diseases are classified according to the muscle groups involved and the age of onset. Some of these muscular dystrophies result in premature death; others may allow the person to live for decades with varying degrees of disability. Symptoms Muscular dystrophy is characterized by muscle weakness in various parts of the body, depending on the type of MD or myopathy. Muscle weakness progresses (worsens) over time. Initial symptoms usually develop gradually. Diagnosis Diagnosis is based on a comprehensive physical examination and sophisticated diagnostic tests. The effectiveness of therapy depends upon accurate diagnosis of the precise type of MD, so physicians here may use advanced diagnostic techniques such as genetic analysis and biopsy of muscle or nerve tissue to pinpoint the type of neuromuscular disease or myopathy. The state-of-the-art neurophysiology lab at the University of Chicago Hospitals provides a full array of diagnostic tests including electrodiagnostic studies. Treatment Adult patients receive care in a multidisciplinary clinic which is sponsored by the

2. Muscular Dystrophies: Information For Non-scientists Leiden Muscular Dystrophy pages ©. Information for nonscientists on musculardystrophies. muscular dystrophies - facts about specific muscular dystrophies. http://www.dmd.nl/nonsciuk.html

Leiden Muscular Dystrophy pages Information for non-scientists on muscular dystrophies (last modified October 4, 2002; with the help of Vladimir Vladimirov) NOTE: most of these items follow links to the homepage of the Muscular Dystrophy Campaign, the MDC Nederlandse versie Contents Research Approaches Towards a Cure - by Günter Scheuerbrandt , updated regularly Muscular dystrophies - facts about specific muscular dystrophies. A.o.; Duchenne muscular dystrophy (DMD) Becker muscular dystrophy (BMD) Limb-Girdle muscular dystrophy (LGMD / SCARMD) Emery-Dreifuss muscular dystrophy (EMD) ... Tests to detect muscular dystrophy carriership : prenatal diagnosis a muscle biopsy: what happens ? / what is how analysed ? European directory of laboratories performing DNA diagnosis: EDDNAL The long road to therapy : the many steps to take / how far are we (per muscular dystrophy) ? Potential therapies viral vectors: what are these ? clinical trials: what has been tried ? / what was the success ? Explanation of terms Glossary of terms Heredirary of muscular mystrophy (Genetics): DNA, genes, chromosomes, cells

3. Muscular Dystrophy Campaign - Inheritance And The Muscular Dystrophies Inheritance and the muscular dystrophies. This document provides dystrophies.How are the muscular dystrophies inherited? The way http://www.muscular-dystrophy.org/information/Research/inherit.html

Inheritance and the muscular dystrophies This document provides a brief summary of the genetics of the muscular dystrophies. An understanding of their inheritance patterns makes it possible for families to know what the risk is of the dystrophy happening again. If, after reading this, you feel that any member of your family may be an unrecognised carrier of muscular dystrophy, or may have the condition themselves, do get expert advice from a genetic centre. New genetic tests can help trace, within families, those members with the abnormal gene for many muscular dystrophies. How are the muscular dystrophies inherited? The way in which our bodies grow and work is controlled by structures called genes. Genes are parts of chromosomes which are strands of biochemical material transmitted from every cell to its offspring. We have two genes for every hereditary characteristic and function, one inherited from each parent. Sometimes a gene is faulty in part of its structure with the result that a certain bodily process is impaired and this fault may then be passed on to the children. There are three main types of inheritance, and when a gene is faulty the fault is inherited in one of these ways with differing results.

4. Facts About Duchenne And Becker Muscular Dystrophies | MDA Publications Serwis Katalog w Wirtualna Polska S.A. pierwszy portal w Polsce. http://www.mdausa.org/publications/fa-dmdbmd-what.html

New 4/00 Facts About Duchenne and Becker Muscular Dystrophies (DMD and BMD) Muscular Dystrophy Association Introduction What are Duchenne and Becker Muscular Dystrophies? Does it Run in the Family? What Can Be Done to Treat DMD or BMD? ... MDA is Here to Help You WHAT ARE DUCHENNE AND BECKER MUSCULAR DYSTROPHIES? What Causes Duchenne and Becker Muscular Dystrophies? What Happens to the Voluntary Muscles of Someone with DMD or BMD? What Tests are Used to Diagnose DMD and BMD? In the early stages, Duchenne and Becker MD affect the pectoral muscles (which draw back the shoulders), the trunk, and the upper and lower legs. These weaknesses lead to difficulty in rising, climbing stairs and maintaining balance. Muscular dystrophies are genetic disorders characterized by progressive muscle wasting and weakness that begin with microscopic changes in the muscle. As muscles degenerate over time, the person's muscle strength declines. Duchenne muscular dystrophy (DMD) was first described by the French neurologist Guillaume Benjamin Amand Duchenne in the 1860s. Becker muscular dystrophy (BMD) is named after the German doctor Peter Emil Becker, who first described this variant of DMD in the 1950s.

5. DMD DUCHENNE MUSCULAR DYSTROPHY From the MDA comes this fact sheet about these types of muscular dystrophy. Review details of diagnosis, symptoms and related health problems. What Are muscular dystrophies? The muscular dystrophies are a group of muscle diseases which have three features in http://www.mda.org.au/specific/mdadmd.html

FACT SHEET MUSCULAR DYSTROPHIES: DUCHENNE AND BECKER What Are Muscular Dystrophies? The muscular dystrophies are a group of muscle diseases which have three features in common: they are hereditary; they are progressive; and each causes a characteristic, selective pattern of weakness. This fact sheet deals only with the Duchenne type muscular dystrophy (DMD) and Becker type muscular dystrophy (BMD). Please contact the Muscular Dystrophy Association for information about other types of muscular dystrophy and related neuromuscular disorders. Why are DMD and BMD discussed together? DMD and BMD cause similar patterns of weakness and disability and are inherited in the same way. Weakness and disability are more severe in DMD and in BMD. Becker dystrophy is like a less severe form of Duchenne dystrophy. Recently it was shown that DMD and BMD are due to defects of the same gene. The normal function of the gene is to enable muscle fibres to make a particular chemical substance, a protein called dystrophin. Muscle fibres in people affected with DMD are extremely deficient in dystrophin, in BMD the deficiency is less severe. DUCHENNE MUSCULAR DYSTROPHY (DMD) What would make a doctor suspect Duchenne Dystrophy (DMD)?

6. LATTER ONSET MUSCULAR DYSTROPHY MDs LATTER ONSET FACT SHEET. muscular dystrophies OF LATTER ONSET What is Muscular Dystrophy? Distalmuscular dystrophy is the rarest subgroup of dystrophies. http://www.mda.org.au/specific/mdalaton.html

FACT SHEET MUSCULAR DYSTROPHIES OF LATTER ONSET What is Muscular Dystrophy? Muscular Dystrophy is a general designation of a group of chronic, hereditary disease characterised by the progressive degeneration and weakness of voluntary muscles. At What Age Do Signs Of Dystrophy Appear? Contrary to the wide spread notion that muscular dystrophy is exclusively a childhood disorder, clinical onset may occur at any point in the life span. The different types of the disease vary in the age which muscle wasting becomes manifest and in the muscle groups first affected. This pamphlet deals mainly with those muscular dystrophies of latter onset - Limb Girdle MD - Congenital MD - Opthalmoplegic MD - Distal MD. Refer to additional links for information on FacioScapuloHumeral (FSH) MD - Myotonic MD or complete list of 40 NMDs The Muscular Dystrophy Association produces a separate pamphlet on the early onset diseases namely Duchenne and Becker Muscular Dystrophy Does The Rate Of Progression Vary? Degeneration of muscle in muscular dystrophy is a continuing process, with considerable variation in its rate and severity among the different forms of the disease. As a rule, it can be said that the earlier the clinical signs appear, the more rapid the progression and the more widespread and disabling the deterioration.

7. LMDp: Gene, Protein And Disease Table Leiden Muscular Dystrophy pages ©. muscular dystrophies the diseases. (lastmodified February 2, 2003). Contents. muscular dystrophies / mutation databases. http://www.dmd.nl/md.html

Leiden Muscular Dystrophy pages Gene, protein and disease Table (last modified March 10, 2003) Protein Synomym Gene symbol Location Disease MIM nr. Reference animal dystrophin DMD DMD, BMD, XLDC Monaco Koenig mouse, dog, cat ... alpha-dystrobrevin 87 kDa, DTNA Sadoulet-Puccio beta-dystrobrevin DTNB ... utrophin DMDL, UTRN Pearce knock-out dystrophin related protein 2 Roberts dystroglycan a alpha- cranin Ibraghimov-Beskrovnaya knock-out Williamson beta- cranin myotilin TTID LGMD-1A Hauser lamin A/C LMNA LGMD-1B Muchir knock-out: Sullivan et al. (1999) De Sandre-Giovannoli EMD2 (AD-EMD), AR-EMD Bonne Raffaele di Barletta Fatkin PLD Shackleton CMT2 (AR-CMT2, De Sandre-Giovannoli Bouhouche De Sandre-Giovannoli calpain-3 LGMD-2A Richard caveolin-3 LGMD-1C hyperCKemia RMD Minetti McNally Carbone Betz knock-out Hagiwara Galbiati Sunada unknown LGMD-1D Speer dysferlin DYSF LGMD-2B, MM (Miyoshi) Liu Bashir SJL mouse Bittner emerin EMD X-EMD Bione sarcoglycan alpha A2, adhalin, SL50 SGCA ARMD, LGMD-2D Roberds knock-out Duclos beta SGCB ARMD, LGMD-2E

8. Muscular Dystrophies muscular dystrophies Guide picks. Feature article Jerry's Kids is a look at thenine types of muscular dystrophies that affect both children and adults. http://rarediseases.about.com/cs/musculardystrophy/

zfp=-1 About Rare/Orphan Diseases Search in this topic on About on the Web in Products Web Hosting Rare/Orphan Diseases with Mary Kugler Your Guide to one of hundreds of sites Home Articles Forums ... Help zmhp('style="color:#fff"') Subjects BUYER'S GUIDE Before You Buy Top Picks Sites for Online Specialty Shopping ... All articles on this topic Stay up-to-date! Subscribe to our newsletter. Advertising Free Credit Report Free Psychics Advertisement Muscular dystrophies Guide picks Muscular dystrophy is the overall name for a group of inherited muscle disorders that cause progressive weakening. Feature article "Jerry's Kids" is a look at the nine types of muscular dystrophies that affect both children and adults. Muscular Dystrophy General Information Links to general information on muscular dystrophy and its different types. Congenital Muscular Dystrophy page Congenital muscular dystrophy is evident from birth. Its symptoms are generalized muscle weakness and fixed deformities of joints (arthrogryposis). Duchenne and Becker MD page Duchenne and Becker muscular dystrophies are the most common. Find links here to information and resources for both disorders. Facioscapulohumeral (FSH) MD page Links to information and resources for facioscapulohumeral (FSH) muscular dystrophy.

9. Other Muscular Dystrophies Links to information and resources for other muscular dystrophies,such as EmeryDreifuss, ophthalmoplegic, and distal. http://rarediseases.about.com/cs/othermds/

zfp=-1 About Rare/Orphan Diseases Search in this topic on About on the Web in Products Web Hosting Rare/Orphan Diseases with Mary Kugler Your Guide to one of hundreds of sites Home Articles Forums ... Help zmhp('style="color:#fff"') Subjects BUYER'S GUIDE Before You Buy Top Picks Sites for Online Specialty Shopping ... All articles on this topic Stay up-to-date! Subscribe to our newsletter. Advertising Free Credit Report Free Psychics Advertisement Other Muscular Dystrophies page Guide picks Other muscular dystrophies, such as Emery-Dreifuss, ophthalmoplegic, and distal. Feature article on this site "Jerry's Kids" examines the nine types of muscular dystrophies that can affect children and adults. MDA USA: Distal Muscular Dystrophy Information from the Muscular Dystrophy Association USA. MDA USA: Emery-Dreifuss Muscular Dystrophy Information from the Muscular Dystrophy Association USA. MDC: Emery-Dreifuss Muscular Dystrophy Information from the Muscular Dystrophy Campaign (U.K.). MSA USA: Oculopharyngeal Muscular Dystrophy Information from the Muscular Dystrophy Association USA. MDA Australia: MD of Latter Onset Information on Limb-Girdle, congenital, ophthalmoplegic, and distal muscular dystrophies, from the Muscular Dystrophy Association of Australia.

10. Www.nlm.nih.gov/cgi/mesh/2K/MB_cgi?term=Muscular+Dystrophies Similar pages MEDLINEplus Medical Encyclopedia Muscular dystrophy Causes, incidence, and risk factors Return to top. The group of diseases calledmuscular dystrophies (MD) includes many inherited disorders such as http://www.nlm.nih.gov/cgi/mesh/2K/MB_cgi?term=Muscular Dystrophies

11. Muscular Dystrophies MAP, muscular dystrophies up. Related topics Hospital. muscular dystrophies;Patient Education Handout Publication Type; Scoliosis. http://omni.ac.uk/browse/mesh/detail/C0026850L0026850.html

Muscular Dystrophies [up] Related topics: other Huntington Disease Neuronal Ceroid-Lipofuscinosis Postpoliomyelitis Syndrome Rett Syndrome ... Treating scoliosis in muscular dystrophy A booklet providing information concerning scoliosis caused by muscular dystrophy, and possible treatments, aimed at the public. Topics include what muscular dystrophy and scoliosis are, treatment, and surgery. Taken from the Iowa Health Book, a part of the University of Iowa’s Virtual Hospital. Muscular Dystrophies Patient Education Handout [Publication Type] Scoliosis Last modified 28/Mar/2003 [Low Graphics]

12. NIH Guide: PATHOGENESIS AND THERAPY OF THE MUSCULAR DYSTROPHIES PATHOGENESIS AND THERAPY OF THE muscular dystrophies Release Date March 20, 1998PA NUMBER PA98-044 PT National Institute of Neurological Disorders and http://grants.nih.gov/grants/guide/pa-files/PA-98-044.html

asknih@od.nih.gov pn13w@nih.go v Richard W. Lymn, Ph.D. Muscle Biology Program National Institute of Arthritis and Musculoskeletal and Skin Diseases Natcher Building Room 5AS49E Bethesda, MD 20892-6500 Telephone: (301) 594-5128 FAX: (301) 480-4543 Email: rl28b@nih.gov Direct inquiries regarding fiscal matter to: Ms. Dawn Richardson Grants Management Branch National Institute of Neurological Disorders and Stroke Federal Building, Room 1004 Bethesda, MD 20892 Telephone: (301) 496-9231 FAX: (301) 402-0219 Email: da8h@nih.gov Ms. Sally A. Nichols Grants Management Officer National Institute of Arthritis and Musculoskeletal and Skin Diseases Natcher Building, Room 5AS 49F Bethesda, MD 20892-6500 Telephone: (301) 594-3535 FAX: (301) 480-5450 Email: nicholss@ep.niams.nih.gov Return to Volume Index Return to NIH Guide Main Index Department of Health and Human Services National Institutes of Health (NIH) 9000 Rockville Pike Bethesda, Maryland 20892

13. NIH Guide: THERAPEUTIC AND PATHOGENIC APPROACHES FOR THE MUSCULAR DYSTROPHIES THERAPEUTIC AND PATHOGENIC APPROACHES FOR THE muscular dystrophies Release DateJanuary 4, 2001 PA NUMBER PAS01-041 National Institute of Arthritis and http://grants.nih.gov/grants/guide/pa-files/PAS-01-041.html

http://www.health.gov/healthypeople/ http://grants.nih.gov/grants/funding/modular/modular.htm http://www.ninds.nih.gov/news_and_events/dmdmtngsummary.htm http://www.nih.gov/niams/reports/fshdsummary.htm ... http://grants.nih.gov/grants/guide/notice-files/NOT-OD-00-048.html ); a complete copy of the updated Guidelines is available at http://grants.nih.gov/grants/funding/women_min/guidelines_update.htm http://grants.nih.gov/grants/guide/notice-files/not98-024.html grantsinfo@nih.gov ; and on the internet at http://grants.nih.gov/grants/funding/phs398/phs398.html http://grants.nih.gov/grants/guide/notice-files/not98-030.html Applicants for the program project grant (P01) should contact the NIAMS and NINDS program officers listed under INQUIRIES to discuss their planned projects and to request the Institute's guidelines for program project applications. Guidelines may be found at: http://www.nih.gov/niams/grants/Guidelines/guidelines.htm (NIAMS) and http://www.ninds.nih.gov/funding/ppg_guidelines.htm http://grants.nih.gov/grants/funding/modular/modular.htm http://grants.nih.gov/grants/funding/modular/modular.htm http://www.nih.gov/niams/grants/payline2.htm . NINDS funding strategy may be found at: http://www.ninds.nih.gov/funding/ninds_funding_strategy.htm

14. Facts About Rare Muscular Dystrophies Classification of Congenital muscular dystrophies (CMDs). Disease, Chromosome/Gene,Inheritance Pattern. Problems and Solutions in Congenital muscular dystrophies. http://www.mdausa.org/publications/fa-rareMD.html

Facts About Rare Muscular Dystrophies Congenital, Distal, Emery-Dreifuss and Oculopharyngeal Muscular Dystrophies Dear Friends What Is Muscular Dystrophy? Does It Run In The Family? Congenital Muscular Dystrophy ... MDA Is Here to Help You Mike Neufeldt Dear Friends: W hen I was about a year old, my parents noticed something odd about the way I walked. After many tests it was determined that I had a neuromuscular disease. It took us several years to get a definite diagnosis of Emery-Dreifuss muscular dystrophy If you've recently found out you have a rare form of muscular dystrophy, you understand what my family went through. The rarity of Emery-Dreifuss, congenital, distal and oculopharyngeal muscular dystrophies makes it very important that you get all the information you can about your disorder. This pamphlet will help you get started. Learning that you or your child has a rare form of MD can be frightening and confusing. My parents wondered why I had this disease; we had no history of it in our family. But, as this pamphlet explains, each type of MD is caused by an extremely uncommon genetic defect that people often don't even know they have. You can be sure your disorder wasn't caused by anything you or your parents did, and you didn't catch it from anyone. My family had to make many adjustments because of MD. But we were lucky. Along with great, caring doctors, we had the Muscular Dystrophy Association to help us. From MDA, my folks got the support and information they needed, as well as help with equipment and other services. I was honored to serve as MDA's National Goodwill Ambassador in 1987-88.

15. Laboratory For Gene Therapy Of Muscular Dystrophies Laboratory for Gene Therapy of muscular dystrophies. At least 25% ofthese biopsies are taken from patients with muscular dystrophies. http://www.lmb.uni-muenchen.de/groups/hl/welcome.html

Laboratory for Gene Therapy of Muscular Dystrophies GenZentrum Muscular dystrophies like Duchenne's muscular dystophy (DMD) are amongst the most common hereditary diseases and lead to severe disability and early death. Alternative treatments are not available. Therefore, a successful treatment modality such as somatic gene therapy would constitute substantial clinical and economical benefit. We are confident that we will be able to develop viral vectors and treatment modalities for DMD which will allow to replace a sufficient amount of functionally adequate dystrophin and to significantly improve the clinical phenotype. Furthermore, the results of this project are expected to pave the way for designing efficient gene therapy protocols for other genetic diseases of skeletal muscles, as well as other organs. We will address key scientific and practical issues that must be resolved before human trials of gene therapy for hereditary muscular dystrophies such as DMD can be contemplated. A network of collaborations has been established: The Friedrich-Baur-Institut (director: Prof. Dr. D. Pongratz) is one of the most important centers for the diagnosis and treatment of neuromuscular diseases in Germany. More than 500 muscle biopsies per year are processed. At least 25% of these biopsies are taken from patients with muscular dystrophies.

16. HHMI News: Researchers Identify Defect That Causes Rare Muscular Dystrophies Researchers Identify Defect that Causes Rare muscular dystrophies, This work demonstrates that dystroglycan has two roles in the http://www.hhmi.org/news/campbell4.html

RESEARCH NEWS RESEARCH NEWS GRANT ANNOUNCEMENTS SCIENCE EDUCATION NEWS INSTITUTE NEWS ... Download this story in Acrobat PDF format. (requires Acrobat Reader Researchers Identify Defect that Causes Rare Muscular Dystrophies "This work demonstrates that dystroglycan has two roles in the brain: a developmental role and a synaptic role," said HHMI investigator Kevin Campbell. Subtle defects in the processing of a single protein that provides structural integrity to muscle cells can lead to several devastating forms of muscular dystrophy, according to studies by Howard Hughes Medical Institute researchers and their colleagues at the University of Iowa. The scientists reported in two papers published in the July 25, 2002, issue of the journal Nature that defects in enzymes responsible for the processing of the structural protein dystroglycan are the underlying cause of several rare forms of muscular dystrophy that affect muscles and cause additional developmental brain abnormalities including mental retardation. The new findings will immediately help doctors in providing accurate diagnosis and appropriate genetic counseling to patients and their families. In the longer term, knowing the underlying cause of the muscular dystrophies will help researchers tailor their interventions, according to Howard Hughes Medical Institute investigator

17. OUP USA: The Muscular Dystrophies Medicine or Browse by Subject $106.00 (05) 0192632914 Add to My Basket 2002 In StockS H Standard Table of Contents, The muscular dystrophies Edited by ALAN EH http://www.oup-usa.org/isbn/0192632914.html

Medicine or Browse by Subject In Stock Standard Table of Contents The Muscular Dystrophies Edited by ALAN E. H. EMERY, Royal Devon and Exeter Hospital, Exeter UK The muscular dystrophies are an important group of inherited disorders. They are characterized by muscle wasting and weakness, but vary considerably in their clinical manifestations and severity. This text reviews our understanding of the most important of these disorders. In many instances, the genes and protein products responsible for the dystrophies have been identified and it is now possible to establish a precise diagnosis, detect preclinical cases, identify carriers and offer prenatal dianostic testing. The book goes on to describe the opportunities for management of the symptoms through respiratory care, physiotherapy and surgical correction of contracture, and examines the potential, in the future, for effective treatment utilizing the new techniques of gene and cell therapy. Professor Emery has invited chapters from the leading international experts in the field providing a unique insight into the current situation and the hopes for the future. Publication dates and prices are subject to change without notice.

18. OUP USA: ToC: The Muscular Dystrophies The muscular dystrophies Edited by Alan EH Emery CONTENTS. 1. MuscularDystrophy an evolving concept, Emery 2. Congenital Muscular http://www.oup-usa.org/toc/tc_0192632914.html

The Muscular Dystrophies Edited by Alan E. H. Emery CONTENTS 1. Muscular Dystrophy: an evolving concept, Emery 2. Congenital Muscular Dystrophies, 3. Fukuyama Congenital Muscular Dystrophy, 4. Duchenne Muscular Dystrophy or Meryon's Disease, Emery 5. Becker Muscular Dystrophy, 6. Emery-Dreifuss Muscular Dystrophy, Toniolo 7. The Limb-Girdle Muscular Dystrophies, Bushby 8. Facioscapulohumeral Muscular Dystrophy, 9. Distal Muscular Dystrophy, 10. Oculopharyngeal Muscular Dystrophy, 11. Dilated Cardiomyopathy and Related Cardiac Disorders in Muscular Dystrophy, 12. Medical Management and Treatment of Muscular Dystrophy, Manzur 13. Respiratory Care in Muscular Dystrophy, Simonds 14. Gene and Cell Therapy for Primary Myopathies, 15. Surgical Management of Muscular Dystrophy, 16. Animal Models of Muscular Dystrophy, General Catalog Information Publication dates and prices are subject to change without notice. Prices are stated in US Dollars and valid only for sales transacted through the US website. Please note: some publications for sale at this website may not be available for purchase outside of the US.

19. THE MERCK MANUAL, Sec. 14, Ch. 184, Muscular Disorders Chapter 184. Muscular Disorders. Topics. muscular dystrophies. Myopathies. Channelopathies.click here for navigation help. muscular dystrophies. http://www.merck.com/pubs/mmanual/section14/chapter184/184a.htm

20. THE MERCK MANUALHome Edition, Sec. 6, Ch. 66, Muscular Duchenne's and Becker's muscular dystrophies. Duchenne's and Becker'smuscular their children. Other muscular dystrophies. Several much http://www.merck.com/mrkshared/mmanual_home/sec6/66.jsp

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