1. Myelodysplastic Syndromes - Leukaemia Research Fund Booklet A look at the causes, types, signs and symptoms, diagnosis, treatment and prognosis of myelodysplastic Category Health Conditions and Diseases myelodysplastic syndromes...... booklet. myelodysplastic syndromes. What are the myelodysplastic syndromes?There are five forms of myelodysplastic syndrome Refractory http://dspace.dial.pipex.com/lrf-/diseases/mds_book.htm

home patient information myelodysplastic syndromes myelodysplastic syndromes patient booklet Myelodysplastic Syndromes The booklets in this series are intended to provide general information about the diseases they describe. In many cases the treatment of individual patients will differ from that described in the booklets. At all times patients should rely on the advice of their specialist who is the only person with full information about their diagnosis and medical history. Causes Types of myelodysplastic syndrome Signs and symptoms Diagnosis ... Prognosis What are the myelodysplastic syndromes? There are five forms of myelodysplastic syndrome: Refractory anaemia Refractory anaemia with ring sideroblasts Refractory anaemia with excess blasts Refractory anaemia with excess blasts in transformation Chronic myelomonocytic leukaemia The myelodysplastic syndromes (MDS) are a group of diseases in which the production of blood cells is severely disrupted. The term myelodysplasia may be used to refer to the effects of myelodysplastic syndrome on the bone marrow. In contrast to leukaemia in which one type of blood cell is produced in excessively large numbers the production of any, and sometimes of all, types of blood cells is affected in myelodysplastic syndrome. The poor quality of the blood cells produced means that a significant proportion of them are destroyed before they leave the bone marrow. This means that the levels of red cells, white cells and platelets in the blood may be abnormally low. When the levels of all types of blood cells are low the condition is called pancytopaenia.

2. Myelodysplastic Syndromes Foundation HomePage Information about the organization as well as the disease itself. Offers research updates, international Category Health Conditions and Diseases myelodysplastic syndromes...... The MDS Foundation is a multi disciplinary, international organization devotedto the prevention, treatment, and study of the myelodysplastic syndromes. http://www.mds-foundation.org/

Contact us: 36 Front Street, Crosswicks, NJ 08515 Phone:1-800-MDS-0839 outside the US only: 609-298-6746 kheptinstall@mds-foundation.org Announcement: Updated Handbook Search for Erik Johnson Memorium The MDS Foundation is a multi disciplinary, international organization devoted to the prevention, treatment, and study of the myelodysplastic syndromes. The organization is based upon the premise that international cooperation will accelerate the process leading to the control and cure of these diseases. Patient Services The MDS Foundation is pleased to share with our patients and their families that flight services are available within the continental United States to assist with special medical needs. AirLifeLine is a nationwide organization of over 1,100 pilots who are caring, committed and compassionate individuals donating their time, aircraft and fuel to provide free transportation for patients in financial need. Generally, the criteria for patient travel with us are: The patient must be ambulatory or be mobile enough to board and exit the aircraft. The patient must be able to sit in a seat and wear a seatbelt. Patient may bring along a family member or a support person to assist them. In the case of a child, both parents may travel.

3. Aplastic Anemia & MDS International Foundation, Inc. - Serving Patients With Apl Fighting Aplastic Anemia, myelodysplastic syndromes, and other bone marrow failure.Category Health Conditions and Diseases Anemia Aplastic......Aplastic Anemia MDS (myelodysplastic syndromes) International Foundation,Inc. serves as a resource directory for patient assistance http://www.aplastic.org/

In The News - Updates on diseases and treatments. Frequently Asked Questions Want to Talk? - Network with other patients and families. Enroll in our Patient Registry to help researchers compile data on these diseases Merchandise Purchases help Fight AA and MDS You are Visitor No: P.O. Box 613 Annapolis, Maryland 21404-0613 USA Tel: 800.747.2820 Fax 410.867.0240 E-Mail help@aamds.org We subscribe to the HONcode principles of the Health On the Net Foundation This site was selected for inclusion in Current Web Contents , published by ISI (Institute for Scientific Information); and MedlinePlus Health Information , published by NLM (National Library of Medicine). Site designed, marketed and maintained by Vansant Creations Web Development "Like Having Your Own Personal Nerd" This site is hosted by Toad.net

4. Myelodysplastic Syndromes A description of what these diseases are, alternate names, and links for both patient and professional information. http://dspace.dial.pipex.com/lrf-/diseases/mds.htm

home patient information myelodysplastic syndromes Myelodysplastic syndromes Leukaemia Research Fund produces a booklet on The Myelodysplastic Syndromes, which provides general information on the disease. To download this booklet as a PDF click here . To view a copy of this booklet click here Useful links for health professionals Patient publications on the web Reviews Key information Teaching aids ... Scientific meetings The myelodysplastic syndromes (MDS) are a group of diseases in which the production of blood cells is severely disrupted. The term myelodysplasia may be used to refer to the effects of myelodysplastic syndrome on the bone marrow. In contrast to leukaemia in which one type of blood cell is produced in excessively large numbers the production of any, and sometimes of all, types of blood cells is affected in myelodysplastic syndrome. Synonyms: Refractory Anaemia; Preleukaemia; Chronic Myelomonocytic Leukaemia

5. Myelodysplastic Syndromes Lecture outline on myelodysplastic syndromes myelodysplastic syndromes. ©Bruce M. Small, M.D. http://www.smbs.buffalo.edu/med/hem/mds.html

Myelodysplastic Syndromes Bruce M. Small, M.D. State University of New York at Buffalo October 2, 2001 I. The term "dysmyelopoietic or myelodysplastic syndrome" refers to a qualitative and quantitative abnormality of hematopoietic cells, sometimes progressing to acute leukemia. Specifically excluded are dyshematopoietic states with a well-understood, reversible basis such as B12 or folate deficiency. II. FAB classification - an attempt to systematize the recognition of preleukemic subtypes A. History Before FAB, the term "preleukemia" was used to refer to a myeloproliferative disorder which preceded the development of acute leukemia. The definition excluded certain groups at high risk, such as Downs' syndrome, irradiated patients, polycythemia vera, myelofibrosis, CML, etc. Since acute leukemia was not an inevitable development in those diagnosed with preleukemia, and since the term encompassed a wide clinical variation, it was necessary to refine our understanding of these diseases. Thus, the FAB classification. B. FAB distinguishes two groups on the basis of marrow cellularity

6. Myelodysplastic Syndrome Hub myelodysplastic syndromes are a group of diseases in which the bone marrowdoes not function normally and not enough normal blood cells are made. http://www.knowdeep.org/myelodysplastic/

Myelodysplastic syndromes are a group of diseases in which the bone marrow does not function normally and not enough normal blood cells are made. They are fatal disorders which lead to death either through bone marrow failure or by transformation to leukemia. Myelodysplastic Syndrome by National Center Institute Cytogenetic and Molecular Evaluation in Myelodysplastic Syndrome and in Acute and Chronic Leukemia - by Peter R. Papenhausen, PhD, Lynn C. Moscinski, MD, and Cameron G. Binnie, PhD. Stanford Myelodysplastic Syndrome (MDS) Center - under the direction of Dr. Peter Greenberg, Professor of Medicine/Hematology. Myelodysplastic Syndrome from eMedicine - by Emmanuel C Besa, MD, Professor, Department of Internal Medicine, Division of Hematology and Oncology, Medical College of Pennsylvania Hahnemann University. Myelodysplasia at Johns Hopkins Aplastic Anemia, Myelodysplastic Syndrome, and Paroxysmal Nocturnal Hemoglobinuria (PNH) - by the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins. Analysis of Myelodysplastic Syndrome Clones Arising After Multiple Myeloma - a case study by correlative interphase cytogenetic analysis by Yukio Kobayashi, Michihiro Nakayama, Naoki Uemura, Kunihiko Takeyama, Kensei Tobinai, Takeaki Takenaka, Soon Hee Choi, Hitoshi Satoh, Shigeo Mori and Shigetaka Asano.

7. Myelodysplastic Syndromes The myelodysplastic syndromes (MDS) are a group of bone marrow disorders usually presenting with symptoms related to http://www.thedoctorsdoctor.com/diseases/myelodysplasia.htm

Background The myelodysplastic syndromes (MDS) are a group of bone marrow disorders usually presenting with symptoms related to deficiencies of one or more of the bone marrow elements. Anemia, bleeding problems, and infections are all presenting symptoms. The diagnosis can only be made by the pathologist by examining a bone marrow aspirate and biopsy. EPIDEMIOLOGY CHARACTERIZATION SYNONYMS MDS, Preleukemia INCIDENCE The following percentages are from a total number of MDS patients Refractory Anemia (RA) Refractory anemia with ringed sideroblasts (RARS) Refractory anemia with excess of blasts (RAEB) Refractory anemia with excess of blasts in transformation (RAEB-T) Chronic myelomonocytic leukemia (CMML) AGE RANGE-MEDIAN DISEASE ASSOCIATIONS CHARACTERIZATION RELAPSING POLYCHONDRITIS Myelodysplastic syndrome associated with relapsing polychondritis: unusual transformation from refractory anemia to chronic myelomonocytic leukemia. Shirota T, Hayashi O, Uchida H, Tonozuka N, Sakai N, Itoh H. Department of Internal Medicine, Tokyo Medical College Hospital, Japan.

8. Myelodysplastic Syndromes - CancerIndex myelodysplastic syndromes, sometimes called "preleukaemia" are a group of diseases in which the bone marrow does not http://www.cancerindex.org/clinks4d.htm

Home Site Map Cancer Types Treatments ... About Myelodysplastic Syndromes Home Cancer Types Hematological Myelodysplastic Syndromes Myelodysplastic Syndromes (6 links) Myelodysplastic syndromes, sometimes called "pre-leukaemia" are a group of diseases in which the bone marrow does not produce enough normal blood cells. Common symptoms are anaemia, bleeding, easy bruisability, and fatigue. These Myelodysplastic syndromes can occur in all age groups but are more common in people aged over 60. Myelodysplastic syndromes may develop spontaneously or be secondary to treatment with chemotherapy / radiotherapy. There is an association with Myelodysplastic syndromes and acute myeloid leukaemia. Patient's information for Myelodysplastic Syndromes (CancerNet) Information about the disease, staging, and treatment overviews. It is reviewed each month by a panel of medical experts. Myelodysplastic Syndrome - Booklet (Leukemia and Lymphoma Society, USA) Myelodysplastic Syndromes (Leukemia Research Fund , UK) on-line booklet Myelodysplastic Syndromes Foundation The Foundation was established by a group of international physicians and researchers to provide an ongoing exchange of information about MDS. The web site includes information for patients, health professionals and researchers.

9. Myelodysplastic Syndromes Research Fund produces a booklet on The myelodysplastic syndromes, which provides general information on the disease. http://www.meb.uni-bonn.de/cancernet/102495.html

Treatment statement for Health professionals Myelodysplastic Syndromes Get this document via a secure connection General Information Cellular Classification Stage Information ... Previously Treated Myelodysplastic Syndrome General Information The MDS are characterized by abnormal bone marrow and blood cell morphology. Megaloblastic erythroid hyperplasia with macrocytic anemia associated with normal B12 and folate levels is frequently observed. Circulating granulocytes are frequently severely reduced in number, often hypogranular, and display the acquired pseudo Pelger-Huet abnormality. Early, abnormal myeloid progenitors are identified in the marrow in varying percentages, depending on the type of myelodysplastic syndrome. Abnormally small megakaryocytes (micromegakaryocytes) are seen in the marrow and hypogranular or giant platelets appear in the blood. ] Anemia, bleeding, easy bruisability, and fatigue are common initial findings. Splenomegaly or hepatosplenomegaly may occasionally be present. Approximately half of the patients have a detectable cytogenetic abnormality, usually a deletion of all or part of chromosome 5 or 7, or trisomy 8. [ ] Although the bone marrow is usually hypercellular at diagnosis, 15% to 20% of patients present with a hypoplastic bone marrow. [

10. Myelodysplastic Syndromes Foundation - Patient Information Arrow myelodysplastic syndromes Foundation features, Understanding MyelodysplasticSyndromes A Patient Handbook Peter A. Kouides, MD John M. Bennett, MD. http://www.mds-foundation.org/patientinfo.html

Myelodysplasia - A Patient's View http://www.ibirch.pwp.blueyonder.co.uk Article provided by: Rex Birch The Myelodysplastic Syndromes: A Review for Patients, Families, Friends, and Healthcare Professionals Guest Editor John M. Bennett, MD University of Rochester Cancer Center Rochester, New York USA Understanding Myelodysplastic Syndromes: A Patient Handbook Peter A. Kouides, MD John M. Bennett, MD Myelodysplasia and its Discontents: What Patients are Thinking and Talking About by: Suzanne Fleischman, PhD Transfusion-Dependent Iron Overload and MDS: A Handbook for Patients Published by: the Myelodysplastic Syndromes Foundation Patient Advocacy Committee click here to download an ADOBE PDF of this document *NOTE* - this is an exact copy of the above article, but available in the format as originally produced and mailed out. *NOTE* This is an ADOBE 3.0 Acrobat File. You must be using an ADOBE 3.0 or greater viewer to properly view this file. Click here to access more information on acquiring a compatible viewer.

11. Aplastic Anemia & MDS International Foundation, Inc. - Serving Patients With Apl AAMDS's mission is to serve as a resource directory for patient assistance and emotional support; provide educational materials and updated medical information; and financially support research to find effective treatments for aplastic anemia and myelodysplastic syndromes. http://www.aamds.org

In The News - Updates on diseases and treatments. Frequently Asked Questions Want to Talk? - Network with other patients and families. Enroll in our Patient Registry to help researchers compile data on these diseases Merchandise Purchases help Fight AA and MDS You are Visitor No: P.O. Box 613 Annapolis, Maryland 21404-0613 USA Tel: 800.747.2820 Fax 410.867.0240 E-Mail help@aamds.org We subscribe to the HONcode principles of the Health On the Net Foundation This site was selected for inclusion in Current Web Contents , published by ISI (Institute for Scientific Information); and MedlinePlus Health Information , published by NLM (National Library of Medicine). Site designed, marketed and maintained by Vansant Creations Web Development "Like Having Your Own Personal Nerd" This site is hosted by Toad.net

12. M. D. Anderson Cancer Center - Leukemia Department Overview of the various Leukemia and myelodysplastic syndromes, with information about treatment options. Discusses the facility and staff of this department of the University of Texas. http://www.mdanderson.org/departments/leukemia/

Care Center Information A to Z Department List Breast Center Cancer Prevention Gastrointestinal Genitourinary Gynecologic Oncology Internal Medicine Plastic Surgery Radiation Treatment Sarcoma Thoracic Alopecia Areata Aplastic Anemia Basal/Squamous Cell Carcinomas Bladder Blood Stem Cell Transplant Bone Cancer Bone Marrow Failure (pediatric) Bone Marrow Transplants Brain Brain Tumors (pediatric) Breast Cancer Burkitt's Lymphoma Cancer Survivorship Cardiovascular Diseases Central Nervous System Cervical Chemoprevention Chest Wall and Sternal Tumors Childhood Cancers Colorectal Complementary Medicine Dermatology - General Endometrial Esophageal Ewing's Sarcoma - pediatric Eye Cancers Eyelid/Orbital Tumors Fallopian Tube Germ Cell Tumors Germ Cell Tumors (pediatric) Gestational Trophoblastic Disease Graft Vs. Host Disease (GVHD) Head and Neck Cancers Hematologic Malignancies Hereditary Gynecologic Cancers Hodgkin's Disease Hodgkin's Disease (pediatric) Idiopathic Hypereosinophilic Synd Kidney Larynx Leptomeningeal Disease Leukemia Leukemia (pediatric) Liver Tumors Lung Lymphoblastic Lymphoma Lymphoma Lymphoma - Cutaneous T-Cell Mediastinal Tumors Medulloblastoma (pediatric) Melanoma Melanoma (eye) Melanoma (head and neck area) Mesothelioma Myelodysplastic Syndrome Myeloma - Multiple Nasopharynx Neuroblastoma (pediatric) Neurofibromatosis (pediatric) Non-Hodgkin's Lymph. (pediatric)

13. Cancer.gov - Myelodysplastic Syndromes (PDQ®): Treatment What are myelodysplastic syndromes? myelodysplastic syndromes, also called preleukemia or "smoldering" leukemia, are http://cancer.gov/templates/page_print.aspx?viewid=f3133a91-a7e0-4d6c-acf2-06fbe

14. Myelodysplastic Syndromes myelodysplastic syndromes CME Authors Razelle Kurzrock, MD; Moshe Talpaz, MD;Fan Zhang, MD Disclosures Release Date February 1, 2001; Valid for credit http://www.medscape.com/viewprogram/115

Focus On... ADHD ALLHAT Alzheimer's Disease Anthrax Asthma Biologic Therapies Bipolar Disorder Breast Cancer Depression Erectile Dysfunction Genital Herpes GERD Geriatric Care Heart Failure Heart Failure: CRT Hepatitis C HIPAA Home Defib in SCA Hyperlipidemia IBS InfluenZone Insulin Pump Tx Kidney Disease Menopause Micro Complications Multiple Sclerosis Osteoporosis Ovarian Cancer Pain Management Pancreatic Cancer Patient Safety Rheum Arthritis Schizophrenia Secondary Anemia Serious Mental Ill Sports Medicine UTI-Zone Weight Management Related Topics Health Diversity Hospice Care Medical Privacy Welcome, March 31, 2003 Myelodysplastic Syndromes CME Authors: Razelle Kurzrock, MD; Moshe Talpaz, MD; Fan Zhang, MD Disclosures Release Date: February 1, 2001 Valid for credit through January 31, 2003 Credit Hours Available Physicians - up to 2.0 AMA PRA category 1 credit(s); Pharmacists - up to 2.0 contact hour(s) (0.2 CEUs); Registered Nurses - up to 2.4 Nursing Continuing Education contact hour(s) Contents of This CME Activity Myelodysplastic Syndromes Historical Background of Myelodysplastic Syndromes Classification of Myelodysplastic Syndromes Treatment of Myelodysplastic Syndromes Cytokines for Patients With Myelodysplastic Syndromes?

15. Cancer.gov - URL Changed General information, cellular classification, stage information, treatment options, de nova, secondary and previously treated myelodysplastic syndromes. http://cancernet.nci.nih.gov/cgi-bin/srchcgi.exe?TYPE=search&ZUI=208_02495P&

16. Myelodysplastic Syndromes myelodysplastic syndromes. Bruce M. Small, M.D. http://www.smbs.buffalo.edu/med/mds.html

Myelodysplastic Syndromes Bruce M. Small, M.D. State University of New York at Buffalo I. The term "dysmyelopoietic or myelodysplastic syndrome" refers to a qualitative and quantitative abnormality of hematopoietic cells, sometimes progressing to acute leukemia. Specifically excluded are dyshematopoietic states with a well-understood, reversible basis such as B12 or folate deficiency. II. FAB classification - an attempt to systematize the recognition of preleukemic subtypes A. History 1. Before FAB, the term "preleukemia" was used to refer to a myeloproliferative disorder which preceded the development of acute leukemia. The definition excluded certain groups at high risk, such as Downs' syndrome, irradiated patients, polycythemia vera, myelofibrosis, CML, etc. 2. Since acute leukemia was not an inevitable development in those diagnosed with preleukemia, and since the term encompassed a wide clinical variation, it was necessary to refine our understanding of these diseases. Thus, the FAB classification. B. FAB distinguishes two groups on the basis of marrow cellularity

17. Member Sign In Return to myelodysplastic syndromes. Bennett JM, Catovsky D, Daniel MT, et al. Proposalsfor the classification of the myelodysplastic syndromes. Br J Haematol. http://www.medscape.com/viewarticle/412739_8

If you are having trouble logging in: In order to use Medscape, your browser must be set to accept "cookies." To find out how to adjust your browser settings, please click here Log In Username Password Forgot your password? Not a Member? Register Now for free access to: MEDLINE (Optimized for Physicians) 200+ Free CME Courses 25 Medical Specialty Sites 100+ Medical Journals Conference Coverage Daily Medical News About Medscape Help WebMD Health

18. Cancer.gov - Myelodysplastic Syndromes (PDQ®): Treatment . What are myelodysplastic syndromes?...... Date Last Modified 08/27/2002, health professional, myelodysplastic syndromes. returnto top. http://www.cancer.gov/cancerinfo/pdq/treatment/myelodysplastic/patient/

Two versions of this document are available. Select a tab below to switch between versions. Date Last Modified: 08/27/2002 Myelodysplastic Syndromes Description What are myelodysplastic syndromes? Stage Explanation Stages of myelodysplastic syndromes ... About PDQ Description What are myelodysplastic syndromes? Myelodysplastic syndromes, also called pre-leukemia or "smoldering" leukemia, are diseases in which the bone marrow does not function normally and not enough normal blood cells are made. The bone marrow is the spongy tissue inside the large bones in the body. The bone marrow makes red blood cells (which carry oxygen and other materials to all tissues of the body), white blood cells (which fight infection), and platelets (which make the blood clot). Normally, bone marrow cells called blasts develop (mature) into several different types of blood cells that have specific jobs in the body. Myelodysplastic syndromes occur most often in older people, but they can occur in younger people. The most common sign is anemia, which means there are too few mature red blood cells to carry oxygen. There may also be too few white blood cells in the blood to fight infections. If the number of platelets in the blood is lower than normal, this may cause people to bleed or bruise more easily. A doctor should be seen if a person bleeds without any reason, bruises more easily than normal, has an infection that won't go away, or feels tired all the time. If there are symptoms, a doctor may order blood tests to count the number of each kind of blood cell. If the results of the blood test are not normal, the doctor may do a bone marrow biopsy. During this test, a needle is inserted into a bone and a small amount of bone marrow is taken out and looked at under the microscope. The doctor can then determine the kind of disease and plan the best treatment.

19. Cancer.gov - Myelodysplastic Syndromes (PDQ®): Treatment myelodysplastic syndromes (PDQ®) Treatment printable version, Two versionsof this document are available. patient, myelodysplastic syndromes. http://www.cancer.gov/cancerinfo/pdq/treatment/myelodysplastic/healthprofessiona

Two versions of this document are available. Select a tab below to switch between versions. Date Last Modified: 01/02/2003 Myelodysplastic Syndromes General Information Cellular Classification Refractory anemia (RA) Refractory anemia with ringed sideroblasts (RAS) ... Previously Treated Myelodysplastic Syndrome General Information The MDS are characterized by abnormal bone marrow and blood cell morphology. Megaloblastic erythroid hyperplasia with macrocytic anemia associated with normal B12 and folate levels is frequently observed. Circulating granulocytes are frequently severely reduced in number, often hypogranular, and display the acquired pseudo Pelger-Huet abnormality. Early, abnormal myeloid progenitors are identified in the marrow in varying percentages, depending on the type of myelodysplastic syndrome. Abnormally small megakaryocytes (micromegakaryocytes) are seen in the marrow and hypogranular or giant platelets appear in the blood. ] Anemia, bleeding, easy bruisability, and fatigue are common initial findings. Splenomegaly or hepatosplenomegaly may occasionally be present. Approximately half of the patients have a detectable cytogenetic abnormality, usually a deletion of all or part of chromosome 5 or 7, or trisomy 8.[ ] Although the bone marrow is usually hypercellular at diagnosis, 15% to 20% of patients present with a hypoplastic bone marrow.[

20. U-M CCC - Information Guide - Myelodysplastic Syndromes Updated 10/2002. myelodysplastic syndromes Information Guide. Aplastic Anemia MDS International Foundation. myelodysplastic syndromes Basic Explanations. http://www.cancer.med.umich.edu/learn/pwmyesyndrome.htm

Patient Education Resource Center Print-friendly version of this guide Show me other Information Guides (also known as PERC Pathways) Updated 10/2002 Myelodysplastic Syndromes Information Guide The purpose of this Information Guide is to help patients newly diagnosed with myelodysplastic syndromes find sources of information and support. This list is not meant to be comprehensive, but rather to provide starting points for information seeking. The materials can be found at the Patient Education Resource Center of the University of Michigan Comprehensive Cancer Center in room B1-361. Brochures Available in the Patient Education Resource Center on level B-1 The Leukemia & Lymphoma Society. "Myelodysplastic Syndrome (MDS.)" Myelodysplastic Syndromes Basic Explanations Article Mayo Clinic Health Letter. "Myelodysplastic Syndrome: When Blood Cell Production Goes Wrong." ( Mayo Clinic Health Letter ; Vol. 19, No. 3, March 2001, p.4)

A  B  C  D  E  F  G  H  I  J  K  L  M  N  O  P  Q  R  S  T  U  V  W  X  Y  Z

Page 1     1-20 of 86    1  | 2  | 3  | 4  | 5  | Next 20