1. Neutropenia Support Association Inc. An extensive look at this disorder with information about the blood, the causes, the different types, Category Health Conditions and Diseases Blood Disorders neutropenia......Increasing the understanding of neutropenia by providing information andsupport for care givers, patients and their families. Increasing http://www.neutropenia.ca/

Increasing the understanding of neutropenia by providing information and support for care givers, patients and their families. Welcome The Neutropenia Support Assoc. Inc. is a volunteer driven registered charity, that was formed in 1989 to increase awareness and understanding of neutropenia. Neutropenia is a blood disorder you don't often hear about, but it can affect anyone. Some people are born with it. It can happen after a viral infection, or can be drug induced. Some offending agents include some antibiotics, antithyroid agents, tranquilizers, anti-inflammatory agents, antirheumatics, sedatives etc. Exposure to certain poisons can also cause Neutropenia. Neutropenia affects as many as one in three patients receiving chemotherapy for cancer. It is also associated with many other diseases like Lupus (SLE), Malaria, Hepatitis viruses, Rheumatoid Arthritis, Sjogren's Syndrome, Shwachman-Diamond Syndrome, Aplastic Anemia and Myelodysplastic Syndromes, Parvovirus, Felty's Syndrome, to name just a few. Neutropenia can be a serious problem requiring prompt attention. Without proper medical care, patients may find it hard to lead normal lives. Severe cases can be life threatening.

2. Severe Chronic Neutropenia International Registry A disease registry which was established in Australia, Canada, the European Community and the United States in March, 1994. Information for patients and families and health care providers. http://depts.washington.edu/registry/

The Severe Chronic Neutropenia International Registry Welcome to the home page for the Severe Chronic Neutropenia International Registry (SCNIR). The SCNIR is a disease registry which was established in Australia, Canada, the European Community and the United States in March, 1994. This Registry is directed by a scientific advisory board of physicians from around the world who care for SCN patients. The mission of the Registry is to establish a world-wide database of treatment and disease-related outcomes for persons diagnosed with SCN. Collection of this information will lead to improved medical care and is used for research to determine the causes of neutropenia. Information for Patients and Families Information for Health Care Providers Contact Us

3. Neutropenia A description of this blood disorder along with the causes, symptoms and quite an extensive look at Category Health Conditions and Diseases Blood Disorders neutropenia......neutropenia. There are various types of cells in the blood. Neutophils infections.neutropenia is reduction of the number of these cells.. http://www.tirgan.com/leucpnia.htm

Home Services Contact Links ... Chemotherapy Drugs Neutropenia There are various types of cells in the blood. Neutophils are those white blood cells that are first line of defense to fight infections. Neutropenia is reduction of the number of these cells.. It is the most important complication of chemotherapy. It is almost always due to impairment of bone marrow to produce cells and normally occurs a few days to a few weeks after chemotherapy. It is most severe in patients who receive aggressive treatments. Signs and symptoms: The signs and symptoms of Neutropenia depend on its severity. However, patients with even mild forms can develop major problems. Even in the most severe cases, it may have no signs at all, or it may cause fever and infection. A fever in patients who have received chemotherapy must be taken seriously, requiring a complete evaluation. Taking Tylenol or aspirin will only mask the infection and should be avoided, unless prescribed by the medical oncologist after a proper evaluation. Febrile Neutropenia: One technical term of which cancer patients should be aware is "

4. About Neutropenia People with neutropenia get infections early and often. http://www.neutropenia.org/about-2.html

What is your blood made up of Blood is made up of billions of cells. There are many different types of blood cells, but most of the time you hear about two kinds - red cells and white cells. There are many more red cells than any other kind of blood cell. They are very important, because they carry oxygen from your lungs to all the parts of your body. The white blood cells are just as important, but for a very different reason. One of their jobs is to protect you from infection. There are several different kinds of white cells. Each has a special function. The most common ones are: Neutrophils (pronounced NEW TROH FILS), which surround and destroy bacteria in your body; and Lymphocytes (pronounced LIM FOH SITES), which are the key part of your body's immune system, and defend against viruses. A third kind of blood cell, the platelet, helps your blood to clot. Neutrophils and neutropenia Everyone has been sick with an infection at one time or another. That's because it's easy for bacteria and viruses that cause infections to get inside the body. Healthy people don't often get infections even though bacteria and viruses are all around us, even in the air we breathe. The body protects itself against the constant risk of infection by making a lot of neutrophils. They are your main defense against infections. You might think of them as the soldiers that fight the invaders that cause infections.

5. Neutropenia Usually pancytopenia, rather than isolated neutropenia. Bone marrow failure Bone marrow failure is usually associated with pancytopenia, rather than isolated neutropenia. Bone marrow infiltration Chronic idiopathic neutropenia neutropenia. neutropenia. Review clinical features, incl history of exposure to drugs, toxins. http://www.rcpa.edu.au/pathman/neutrope.htm

Neutropenia Neutropenia Review clinical features, incl history of exposure to drugs, toxins. FBC blood film differential WCC bone marrow aspiration See also Febrile neutropenia Decreased production Drug reactions Predictable eg Usually pancytopenia, rather than isolated neutropenia. Cytotoxic drugs Idiosyncratic eg NSAID Sulphonamides Carbimazole Bone marrow failure Bone marrow failure is usually associated with pancytopenia, rather than isolated neutropenia. Irradiation Bone marrow infiltration Acute leukaemia Myelodysplasia Megaloblastic anaemia Usually pancytopenia, rather than isolated neutropenia. Chronic idiopathic neutropenia Hereditary/constitutional eg Cyclic neutropenia Follow-up FBC differential WCC over time. Schwachman syndrome Associated with Pancreatic insufficiency Chediak-Higashi syndrome See under Immunodeficiency Diamond-Blackfan syndrome Organic acidaemias Increased destruction and/or margination Immune SLE Neutrophil antibodies may be helpful. Rheumatoid arthritis Drug reactions eg Drug associated neutrophil antibodies.

6. Medications Which May Reduce The Neutrophil Count (neutropenia). Medications which may reduce the neutrophil count (neutropenia). Medications which may cause neutropenia. acetazolamide. alloprinol http://www.globalrph.com/neutropenia.htm

Medications which may cause neutropenia acetazolamide alloprinol asparaginase captopril carbamazepine cephalosporins chloramphenicol chlordiazepoxide chlorpropamide chlorthalidone cimetidine cyclophosphamide ethacrynic acid fluorouracil furosemide gold salts ibuprofen imipramine indomethasone meprobamate methimazole methotrexate metronidazole nitrofurantoin penicillamine penicillins phenothiazines phenylbutazone phenytoin procainamide procarbazine propylthiouracil quinidine quinine rifampin spironolactone sulfonamides sulindac thioridazine tolbutamide Vancomycin

7. About Neutropenia - Neutropenia Support Association Inc. neutropenia Support Association Inc. What is neutropenia? neutropenia is ablood disorder that can affect anyone. Some people are born with it. http://www.neutropenia.ca/about/

What is Neutropenia Types of Neutropenia Diagnosis and Treatment Living With Neutropenia ... FAQ What is Neutropenia? -NEUTROPENIA, Causes, Consequences, and Care, Provided by The Neutropenia Association Inc.1993 Neutropenia is a blood disorder that can affect anyone. Some people are born with it. It can happen after a viral infection. In some cases the cause can be a side effect of a drug, or exposure to certain poisons. People can get neutropenia when treated for cancer with chemotherapy drugs. Sometimes it happens for no known reason. Blood is made up of billions of cells. There are many different types of blood cells, but most of the time you hear about two kinds - red cells and white cells. There are more red cells than any other type of blood cell. They are very important as they carry oxygen from your lungs to all parts of your body. White blood cells are just as important, but for a very different reason. One of their jobs is to protect you from infection. There are several kinds of white cells. Each has a special function. The most common ones are: Neutrophils (pronounced NEW TROH FILS), which surround and destroy bacteria in your body; and

8. NEUPOGEN® Filgrastim Information for patients, doctors, and healthcare professionals about Neupogen. It is used for treating neutropenia, a common side effect of chemotherapy. http://www.neupogen.com/

Your Resource for the Fight of Your Life. Take control of your fight against cancer by getting the facts about effective treatment Find out what you can do today to get better treatment outcomes tomorrow For healthcare professionals Click here The information provided in this Web Site is intended for residents of the United States. Privacy Statement

9. Severe Chronic Neutropenia International Registry WHAT IS neutropenia? Neutrophils are In some patients, especially thosewith chronic neutropenia, the cause is unknown. If neutropenia http://depts.washington.edu/registry/Neutro.htm

WHAT IS NEUTROPENIA? Neutrophils are blood cells that are produced in the marrow, or core of the bones. The blood normally contains about 1300 to 8000 neutrophils/mm (or often written as 1.5 to 8.0 x 10 per liter of blood). When the number of neutrophils in the blood falls below 1500 cells/mm (1.5 x 10 per liter), the condition is called NEUTROPENIA (new-troh-pee-nee-ah). Neutrophils are very important because they fight infection. When bacteria invade the body, a chemical signal is sent out and the neutrophils, like fire fighters responding to a blaze, rush to the site of infection. The bone marrow also responds by speeding up its production of neutrophils to replace those involved in fighting the infection. If, however, production of new neutrophils is suppressed or slowed down, a shortage may develop, and any infection can overwhelm the few neutrophils available. Therefore, a person with only a few neutrophils is at particular risk for developing a serious bacterial infection. Drugs, chemical agents, physical agents (for example, x-ray treatments) and certain infections can affect the bone marrow's production of cells. Anticancer medications destroy normal cells as well as malignant cells and they often suppress the bone marrow's production of neutrophils. In some patients, especially those with chronic neutropenia, the cause is unknown. If neutropenia does develop, patients must take care to minimize the risk of infection and be prompt in notifying their doctor or other health care provider. Treatments for neutropenia now include antibiotics and drugs which stimulate neutrophil formation.

10. Neulasta Pegfilgrastim - Neutropenia Infection Prevention - Chemotherapy Cancer Information for patients and doctors about fighting cancer chemotherapy induced neutropenia (white blood cell deficiency) and consequent infections with this medicine. http://www.neulasta.com/

11. Neutropenia Suppressed Marrow Production Aplastic anemia, PNH, B12/folate deficiency, myelodysplasia, ChediakHegashi Fanconis anemia, cyclic neutropenia, Kostmans syndrome http://views.vcu.edu/pat/education/hematology/wbc/non-neoplastic/ben-ezra/tsld01

Neutropenia Suppressed Marrow Production Aplastic anemia, PNH, B12/folate deficiency, myelodysplasia, Chediak-Hegashi Hereditary Disorders Fanconi’s anemia, cyclic neutropenia, Kostman’s syndrome Previous slide Next slide Back to first slide View graphic version

12. Imaginis - Neutropenia neutropenia, Format for Printing. neutropenia is an become neutropenic.The most common side effect of neutropenia is high fever. Patients http://imaginis.com/breasthealth/neutropenia.asp

search tips Neutropenia Format for Printing Neutropenia is an abnormal decrease in white blood cells most often resulting from a viral infection or exposure to certain drugs or chemicals. According to the Neutropenia Support Association Incorporated, up to one third of patients who receive chemotherapy (the use of anti-cancer drugs to treat cancer) become neutropenic. The most common side effect of neutropenia is high fever. Patients whose body temperature rises above 101.5 degrees Fahrenheit while undergoing chemotherapy are encouraged to contact their physicians immediately to avoid potentially life-threatening effects of neutropenia. Main Menu: How can breast cancer patients get neutropenia? How are patients with neutropenia treated? Additional types of neutropenia Additional resources and references How Can Breast Cancer Patients Get Neutropenia? For many breast cancer patients, chemotherapy is administered with or without breast surgery or other treatments to kill cancerous cells. Because chemotherapy is a systemic treatment, the drugs travel throughout the body to target cancer cells that may have spread past the breast. The human body is made up of red and white blood cells. Red blood cells carry oxygen to the lungs and different parts of the body while white blood cells protect the body from infection. Neutrophils, one common group of white blood cell produced in the bone marrow, divide and multiply quickly just like cancer cells. Since chemotherapy drugs aim for cancer cells with a high rate of reproduction, many of these neutrophils are also destroyed during treatment, resulting in neutropenia. Neutropenia is defined as a sharp reduction of neutrophils.

13. Pediatric Hematology/Oncology Clinic At The U-M Cancer Center Affiliated with Mott Children's Hospital, the UMCC Pediatric Cancer Clinic at the University of Michigan treats pediatric cancers, as well as sickle cell disease, chronic neutropenias and chronic granulomatous disease. http://www.cancer.med.umich.edu/clinic/pedclinic.htm

Pediatric Hematology/ Oncology Clinic Have questions? Contact us Overview The Pediatric Hematology/Oncology Clinic at the University of Michigan Comprehensive Cancer Center offers a multidisciplinary team of specialists focused on the diagnosis and treatment of pediatric cancers. The majority of visits to the clinic are children with cancer, although patients with sickle cell disease, chronic neutropenias and chronic granulomatous disease are treated as well. Where should my child go for treatment? Learn about our Pediatric Hematology/ Oncology Clinic here. Go here for information, news articles and links on pediatric cancers. Instructions on how to contact us, along with basic information about coming to see us. Meet the physicians and other specialists of the Pediatric Hematology/ Oncology Clinic. We'll let you know where and when they meet and how you can get involved. Learn about the latest treatment studies and who can participate in them.

14. Imaginis - Neutropenia Breast Cancer Treatment. neutropenia, Return to Previous. neutropenia neutropenic.The most common side effect of neutropenia is high fever. http://imaginis.com/breasthealth/neutropenia.asp?mode=1

15. Neutropenia OnLine Register, become a member and participate in a forum about this disorder. http://login.prospero.com/dir-login/index.asp?getDPref=0&webtag=NEUTROPENIA&

16. CancerSymptoms.org :: Neutropenia Learn about neutropenia and what causes it. Find information on different treatmentoptions for neutropenia that are available and may be needed. http://www.cancersymptoms.org/symptoms/neutropenia/

Questions Home Neutropenia Learn Key Points/Overview How To Read a CBC Web Resources Reference List Manage Prevention of Neutropenia Methods of Managing Neutropenia Dietary Considerations Fatigue ... Cognitive Dysfunction Learn about neutropenia and what causes it. Learn about the different cells in your blood and how to read a Complete Blood Count (CBC). Learn about the complications of developing infections while neutropenic, and possible ways to prevent infection. Find information on different treatment options for neutropenia that are available and may be needed. Follow different links to other web-sites that provide additional information and support for neutropenia. This will help you to understand other people's perspectives and experiences with neutropenia. Access articles written on the subject of neutropenia and current guidelines used for treating and managing neutropenia Neutropenia can be managed and treated if necessary. Steps can be taken to try to prevent infections from developing while you are experiencing neutropenia. Identify signs and symptoms that warrant medical attention while neutropenic. Learn about the treatments available for neutropenia. Select One Various Symptoms Fatigue Anorexia Pain Depression Neutropenia Cognitive Dysfunction

17. CancerSymptoms.org :: Neutropenia :: Manage Prevention of neutropenia neutropenia can be an expected side effectof cancer treatment. If you have neutropenia it may not always http://www.cancersymptoms.org/symptoms/neutropenia/manage/prevention.php

Questions Home Neutropenia Learn Key Points/Overview How To Read a CBC Web Resources Reference List Manage Prevention of Neutropenia Methods of Managing Neutropenia Dietary Considerations Fatigue Anorexia ... Cognitive Dysfunction Prevention of Neutropenia Neutropenia can be an expected side effect of cancer treatment. If you have neutropenia it may not always be possible to prevent every potential infection. However, studies have shown that good hand-washing and hygiene are the most effective ways to prevent infection. Prevention Methods Wash your hands before eating and after using the bathroom, sneezing etc. You may use a waterless cleaner if you do not have access to soap and water. Be sure to wash all sides of your hands - 10 seconds is a good length of time. Good oral care is essential - brush your teeth with a soft toothbrush after eating and before bedtime. Take a warm shower every day (hot showers will dry your skin) pat your skin dry (rubbing it will also cause dryness). Avoid people who are ill including children who have the chicken pox or measles or adults who have shingles. Avoid anyone who has had recent immunizations and check with your doctor before you receive any.

18. MayoClinic Answers a patient question as to what neutropenia is and the success of treatment. http://www.mayoclinic.com/home?id=HQ01112

19. Neutropenia – Chemotherapy Side Effects About half of cancer chemotherapy patients develop neutropenia that can placethem at risk for lifethreatening infections. What is neutropenia? http://www.neulasta.com/patient/facts_neutropenia.html

NEUTROPENIA: A SERIOUS AND FREQUENT CHEMOTHERAPY SIDE EFFECT Many cancer patients worry about possible side effects of chemotherapy. A Roper Starch survey of chemotherapy patients found that, prior to starting treatment, 32 percent reported surviving cancer as their biggest concern versus 40 percent who said side effects were their biggest concern. This concern is warranted, as about half of cancer chemotherapy patients develop a condition called neutropenia (new-tro-pee-nee-uh) i that can place them at risk for life-threatening infections. Infections may require hospitalization and can delay chemotherapy treatment and reduce its effectiveness. For more information about Chemotherapy Side Effects, please see Amgen's "Chemotherapy Guidebook" What is neutropenia? Neutropenia is a severe drop in infection-fighting white blood cells (neutrophils). A common side effect of some kinds of chemotherapy, neutropenia is serious because: Thousands of patients are hospitalized for neutropenia each year. This in an age when many cancer patients receive chemotherapy treatment as outpatients. The majority of patients with certain tumors who develop neutropenia will either have their chemotherapy postponed or their dose decreased, both of which can reduce survival rates.

20. Genomelink Database Links to information and resources for neutropenia. http://www.genomelink.org/neutropenia

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