61. Health Library - Olivopontocerebellar Atrophy SEARCH. olivopontocerebellar atrophy. Disorder Subdivisions. OlivopontocerebellarAtrophy I; Spinocerebellar Ataxia Type I (SCA1); OPCA I; Menzel Type OPCA; http://www.muskogeehealth.com/Library/HealthGuide/IllnessConditions/topic.asp?hw

62. Mehler Publishing Company A Division Of Howard S Mehler PhD JD & Associates Inco Infantile olivopontocerebellar atrophy olivopontocerebellar atrophy ISBN 09621181-1-7$19.95 (US) ORDER NOW (40 Pages of Text + 14 Figures including color http://www.mehler.com/infantile.html

Publications Services Contact Us Home Infantile Olivopontocerebellar Atrophy Olivopontocerebellar Atrophy ISBN 0-9621181-1-7 $19.95 (US) ORDER NOW (40 Pages of Text + 14 Figures including color) This monograph clearly illustrates the limitations associated with the genetic screening and diagnosis of this rare and often fatal disease in infants. The report elaborates the subtle differences in clinical presentation and genetic screening for Werdnig-Hoffman Disease vis a vis Olivopontocerebellar Atrophy. The case example provides evidence sufficient to caution geneticists not to confuse the two syndromes when rendering genetic counselling to families. To facilitate the differentiation and diagnosis of these inherited diseases, the report includes 7 authentic magnetic resonance images of an infant afflicted with OPCA, along with 7 histologically stained color muscle biopsy tissue specimens revealing spinal muscular atrophy. CONTENTS I. Patient History

63. Other Ataxias MSA with Cerebellar Ataxia Sporadic olivopontocerebellar atrophy (OPCA)NINDS Pamphlet - olivopontocerebellar atrophy (OPCA). January 1997. http://internaf.org/ataxia/othatax.html

Other Ataxias and related disorders Multiple System Atrophy (MSA): http://www.ndrf.org/MSA.htm June 1997 Acta Neuropathol: The distribution and dynamic density of oligodendroglial cytoplasmic inclusions (GCIs) in multiple system atrophy August 1994 Brain: Clinical features and natural history of multiple system atrophy. Ananalysis of 100 cases. November 1993 Nippon Rinsho: Multiple system atrophy (MSA) MSA with Cerebellar Ataxia - "Sporadic Olivopontocerebellar Atrophy" (OPCA): NINDS Pamphlet - Olivopontocerebellar Atrophy (OPCA) January 1997 Movement Disorders: Cerebellar presentation of multiple system atrophy. March 1996 Movement Disorders: Olivopontocerebellar pathology in multiple system atrophy. MSA With Autonomic Failure - "Shy-Drager Syndrome" (SDS): Jeff's Shy-Drager Page Shy-Drager Syndrome American Autonomic Society CWRU Autonomic Labratory June 1997 Axone: Shy-Drager Syndrome March 1997 New England Journal of Medicine: Autonomic Disorders and Their Recognition MSA with "Striatonigral Degeneration" (SND): January 1997 Nippon Rinsho: Striatonigral Degeneration Episodic Ataxia (EA): Episodic Ataxia Information by Mark Dias OMIM entry for Episodic Ataxia Type 1 OMIM entry for Episodic Ataxia Type 2 OMIM entry for CSE (Choreoathetosis with Spasticity and Episodic Ataxia) Autosomal Recessive Spastic Ataxia of Charelevoix-Saguenay (ARSACS):

64. MSA of MSA, Dr Hain says that MSA is synonymous with striatonigral degeneration (SND)when Parkinsonism predominates, olivopontocerebellar atrophy (OPCA) when http://members.optushome.com.au/wwwombat/interest.htm

What is Multiple System Atrophy (MSA)? I can only describe MSA as a brutal illness. It is rare and very difficult to diagnose. It is not known what causes the illness and there is no cure at this point in time. Very few doctors will actually say for certain that a person has MSA because the only way right now to know for sure that someone had MSA is to do an autopsy. Even if the symptoms all match exactly I don’t think any doctor would say definitely. The best they can do is say "probably". For example, Progressive Supranuclear Palsy (PSP) is very similar to MSA as is Corticobasal Ganglionic Degeneration (CBGD) and Lewy Body Dementia (LBD). When I first started researching MSA across the Internet, I found that there were differing schools of thought as to what MSA is. For me, an excellent description of MSA has been written by Timothy C. Hain, MD Northwestern University Medical School, Chicago, USA. He is without doubt an authority on MSA and you can find him at: http://www.neuro.nwu.edu/meded/MOVEMENT/msa.html

65. Central Nervous System Diseases Atrophies About olivopontocerebellar atrophy fact sheet NINDS (US);The OPCA (olivopontocerebellar atrophy) Awareness site - (CA). http://www.mic.ki.se/Diseases/c10.228.html

search help staff Central Nervous System Diseases Patients and laypersons looking for guidance among the target sources of this collection of links are strongly advised to review the information retrieved with their professional health care provider. Nerve Cells Lodish et al. ] - Molecular Cell Biol., Chap 21, via NLM (US) Pathol. Images of the Central Nervous System - Univ of Utah (US) The Human Brain JD MacArthur The Global Brainstem '97 , the Cerebellum '97 , the Thalamus '97 , the Spinal Cord '97 - Univ. of Wisconsin (US) Mental Disorders Links CENTRAL NERVOUS SYSTEM INFECTIONS Infectious Diseases of the Central Nervous System - The Virtual Hospital, Iowa (US) Arachnoiditis Arachnoiditis mini fact sheet - NINDS (US) Arachnoiditis.net Arachnoiditis Sufferers Action and Monitoring Society New Zealand, Inc. Arachnoiditis Discussions - NeuroWebForum, MGH (US) The UK Arachnoiditis Trust About Adhesive Arachnoiditis , and Classification of Arachnoiditis - The Burton Report Poliomyelitis The Polio Connection of America Poliomyelitis , and the Global Polio Eradication Initiative - WHO (CH) About Polio Vaccines - Sabin Vaccine Institute About the Polio Vaccine and Simian Virus 40 TJ Moriarty ] - Chronic Illnet Postpoliomyelitis Syndrome Post Polio Home Page About the Post-polio Syndrome Lincolnshire Post-Polio Network , and its Library Catalogue T Dempsey ] - (UK) K-H Jeschke ; in German] The Polio Experience Network Post Polio Syndrome Central - S:t Johns Tips about recently published Medical Articles on Post-Polio Syndrome [citations retrieved from Medline]

66. National Organization For Rare Disorders (NORD) olivopontocerebellar atrophy (OPC) and Closely Related NeurologicalDiseases RFP. NORD is accepting applications for one or two http://www.library.utoronto.ca/medicine/research/fmro/fund-opps/March10/nord.htm

67. ENLmedical.com: Conditions And Concerns: Medical Encyclopedia: Olivopontocerebel Table of content. olivopontocerebellar atrophy. Causes and RisksComing soon! Online2000.net Division of Expedition Networks, Ltd. http://www.enlmedical.com/article/000758.htm

Medical Dictionary Naturapathic Glossary Aphrodisiacs Immune System ... Table of content Olivopontocerebellar atrophy Causes and Risks: Coming soon! Expedition's websites are Powered by

68. Health Content Encyclopedia Article Olivopontocerebellar Atrophy olivopontocerebellar atrophy is a neurodegenerative illness that causes certain brainareas (which may include the olivary nucleus, the pons, and the cerebellum http://www.centralbap.com/adamcontent/ency/article/000758.asp

69. Environ Health Perspect 108-3, 2000: Correspondence Rounds in Environmental Medicine, is a case report of an individual who developeda degenerative nervous system disease, olivopontocerebellar atrophy, and who http://ehpnet1.niehs.nih.gov/docs/2000/108-3/correspondence.html

Environmental Health Perspectives Volume 108, Number 3, March 2000 Citation in PubMed Related Articles Carbon Disulfide The September 1998 issue of EHP contained two articles about the neurotoxicity of carbon disulfide. The "NIEHS News" article ( ) reported on a collaborative study that involved scientists from the NIEHS (Research Triangle Park, NC), the U.S. Environmental Protection Agency (Research Triangle Park, NC), the University of North Carolina (Chapel Hill, NC), Duke University (Durham, NC), and Vanderbilt University (Nashville, TN). In this study, the neurotoxicity of carbon disulfide was detailed from the earliest molecular alterations to neurobehavioral findings to electrophysiologic and morphologic changes, and the utility of intramolecular cross-linking in hemoglobin as a biomarker was defined. I was pleased to read this report, and even more pleased to have participated in this study, but I was distressed to see the cover story in the same issue. "Multiple System Atrophy Following Chronic Carbon Disulfide Exposure" ( ), in the "Grand Rounds in Environmental Medicine," is a case report of an individual who developed a degenerative nervous system disease, olivopontocerebellar atrophy, and who had been chronically exposed to carbon disulfide while working for 34 years in a viscose rayon plant in the United States. Frumkin (

70. Multiple System Atrophy Following Chronic Carbon Disulfide Exposure This report describes a case of olivopontocerebellar atrophy, a form of multiplesystem atrophy, developing in an adult after over 30 years of occupational http://ehpnet1.niehs.nih.gov/docs/1998/106p611-613frumkin/abstract.html

Environmental Health Perspectives Volume 106, Number 9, September 1998 Case Study from the Emory Clinic and the Rollins School of Public Health of Emory University Citation in PubMed Related Articles Multiple System Atrophy Following Chronic Carbon Disulfide Exposure Howard Frumkin Department of Environmental and Occupational Health, Rollins School of Public Health of Emory University, Atlanta, GA 30322 USA Abstract Key words : carbon disulfide, cellulose, environmental diseases, movement disorders, multiple system atrophy, occupational diseases, olivopontocerebellar atrophy, rayon, textiles. Environ Health Perspect 106:611-613 (1998). [Online 18 August 1998]. http://ehpnet1.niehs.nih.gov/docs/1998/106p611-613frumkin/abstract.html Address correspondence to H. Frumkin, Department of Environmental and Occupational Health, Rollins School of Public Health of Emory University, 1518 Clifton Road, Atlanta, GA 30322 USA. This work was supported in part by NIEHS Environmental/Occupational Medicine Academic Award 5 KO7 ESO0257. Received 30 July 1998; accepted 3 August 1998.

71. Olivopontocerebellar Atrophy Spanish olivopontocerebellar atrophy. earlier. The cause of sporadic olivopontocerebellaratrophy is not known, but the disease is progressive. http://www.northarundel.com/ency/article/000758.htm

Disease Nutrition Surgery Symptoms Injury ... Encyclopedia (English) Toggle English Spanish Olivopontocerebellar atrophy Overview Symptoms Treatment Prevention Definition: Olivopontocerebellar atrophy is a neurodegenerative illness that causes certain brain areas (which may include the olivary nucleus, the pons, and the cerebellum) to shrink. Alternative Names: OPCA; Olivopontocerebellar degeneration Causes, incidence, and risk factors: This condition can be inherited but it most commonly affects people without a known family history (sporadic form). Sporadic cases tend to affect people in their 50s while familial cases usually start earlier. The cause of sporadic olivopontocerebellar atrophy is not known, but the disease is progressive. Central nervous system Review Date: 7/28/2002 Reviewed By: Elaine T. Kiriakopoulos, M.D., MSc, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard University, Boston, MA. Review provided by VeriMed Healthcare Network.

72. Cleveland Clinic Health System - Health Information Search Results The following information is available for the topic OlivopontocerebellarAtrophy. Please select one. , olivopontocerebellar atrophy. New Search. http://www.cchs.net/health/getcontents.asp?DocID=do-query&TopicId=991

73. Dejerine-Thomas Atrophy (www.whonamedit.com) atrophy, delayed cortical cerebellar degeneration, intracerebellar atrophy, olivopontocerebellarataxia, olivopontocerebellar atrophy, pontoolivocerebellar http://www.whonamedit.com/synd.cfm/1903.html

Home List categories Eponyms A-Z Biographies by country ... Contact Dejerine-Thomas atrophy Also known as: Dejerine-Thomas syndrome Synonyms: Atrophie olivo-ponto-cérébelleuse de Dejerine-Thomas (French), cortical cerebellar degeneration, delayed cerebellar ataxic syndrome, delayed cortical cerebellar atrophy, delayed cortical cerebellar degeneration, intracerebellar atrophy, olivopontocerebellar ataxia, olivopontocerebellar atrophy, ponto-olivocerebellar atrophy, presenile ataxia, presenile cerebellar ataxic syndrome, olivopontocerebellar atrophy, «sporadic form». Associated persons: Joseph Jules Dejerine André Thomas Description: A chronic progressive ataxia characterized by progressive cerebellar atrophy with ataxic disorders of extremities and trunk, equilibrium and gait disorders, slow voluntary movements, speech disorders, nystagmus, and oscillatory tremor of the head and trunk. Onset in adult or middle life. Onset in middle life or later. Progressive ataxia of extremity and trunk. Dysarthria, oscillation of head and body. Mental deterioration present in some cases. Later sphincters affected. Aetiology unknown. Bibliography: J. J. Dejerine, A. Thomas:

74. THE LIGHTNING HYPERTEXT OF DISEASE. Packet No. 1 21765 olivopontocerebellar atrophy (OPCA) A disease with nonuniformpathologic findings and clinical presentation and mode of inheritance (most http://www.pathinfo.com/cgi-bin/lh.cgi?tx=opc

75. Parkinson's Disease Center And Movement Disorders Clinic with three previouslydescribed neurodegenerative disorders Shy-Drager syndrome(SDS), striatonigral degeneration (SND), and olivopontocerebellar atrophy (OPCA http://www.bcm.tmc.edu/neurol/jankovic/educ_msa.htm

Parkinson's Disease Center and Movement Disorders Clinic Multiple System Atrophy Joseph Jankovic, M.D. Previous What and How Next Download Summary ( Printer-Friendly) What is Multiple System Atrophy (MSA)? A. What is Shy-Drager Syndrome (SDS)? Diagnosis is sometimes aided by testing autonomic nervous system function, for example, by measuring blood pressure and heart rate with the patient laying down compared with standing up. A polysomnogram, or sleep study, can document sleep apnea (gaps in breathing during sleep). Brain imaging with CT and MRI are usually helpful in differentiating typical Parkinson's disease from atypical parkinsonism. B. What is Striatonigral Degeneration (SND)?

76. Anticipation In A Family With Autosomal The other systemic and neurological examinations are normal (Figure 1). Her brainCT scan documented advanced olivopontocerebellar atrophy (Figure 2). She has http://www.kfshrc.edu.sa/annals/195/99-027.html

Anticipation in a Family with Autosomal Dominant Spinocerebellar Ataxia M. Al-Essa, MD; O. Dabbagh, MD; P.T. Ozand, MD PhD The autosomal dominant spinocerebellar ataxias (SCA) are a heterogeneous clinical and genetic group of hereditary late-onset neurodegenerative disorders characterized by cerebellar and brainstem dysfunction that are caused by neuronal degeneration in the cerebellum and cranial nerve nuclei. Anticipation, an increase in clinical severity and a younger age of onset of the disease in subsequent generations, is a typical feature of autosomal dominant SCA, and is due to the expansion of the trinucleotide repeats. We report a family of three generations exhibiting this phenomenon. Case Report From the Departments of Peditrics, Neurosciences and Biological and Medical Research, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia. Address reprint requests and correspondence to Dr. Ozand: Department of Biological and Medical Research, MBC-03, King Faisal Specialist Hospital and Research Centre, P.O. Box 3354, Riyadh 11211, Saudi Arabia. became symptomatic with similar clinical findings at 40 and 35 years of age, respectively. It is of interest to find that the grandmother was also symptomatic only three years before her death at the age of 73 years (Figure 3). Detailed genetic study of different family members is in progress.

77. Association For Patient-Oriented Research Multiple System Atrophy and olivopontocerebellar atrophy mentioned.http//www.healthscout.com/cgibin/WebObjects/Af?ap=43 id=107731. http://www.mc.vanderbilt.edu/gcrc/aas/patient resources/SD-MSA news february 200

Shy-Drager/MSA Support Group Multiple System Atrophy News Click figure to go to SDS/MSA Website February 1, 2001 Table of Contents 1. Iron Metabolism and MSA 2. Oxidative Stress and MSA 3. Dr. Sid Gilman to Speak at National Ataxia Foundation Annual Conference 4. Research Articles by Dr. Sid Gilman 5. Curing Parkinson's Disease in Our Lifetime 1. Iron Metabolism and MSA Iron Problems May Lead to Parkinson's: Mouse study shows direct link January 30, 2001 article. Multiple System Atrophy and Olivopontocerebellar atrophy mentioned. Mouse With Iron Disorder Offers Clues To Parkinson's, Similar Diseases January 31, 2001 article. MSA and OPCA mentioned 2. Oxidative Stress and MSA Oxidative Damage Linked Directly to Neurodegeneration November 3, 2000 article. MSA is mentioned http://www.grg.org/ParkO2Dam.htm Evidence Links Protein Damage To Parkinson's November 3, 2000 article - MSA and other synucleinopathies are included in this article http://www.sciencedaily.com/releases/2000/11/001103071439.htm Oxidative Stress and Brain Disorders This article gives some background on what oxidative or "free radical" damage is.

78. Multi System Atrophy Links Shy Drager Syndrome. Idiopathic Orthostatic Hypotension; ShyDrager Syndrome(The Merck Manual). olivopontocerebellar atrophy olivopontocerebellar atrophy. http://msainfo.tripod.com/msalinks.html

There is no order to these links under the heading. They are randomly placed by me. General Information Neuroscience Web Search Nervous System Diseases DIFFERENTIAL DIAGNOSIS OF PARKINSON'S DISEASE AND THE PARKINSONISM PLUS SYNDROMES Parkinsonism More Common Than Thought ... Multiple System Atrophy NDRF Multiple System Atrophy (MSA) MultiSystem atrophy -Neurology Channel We Move Autonomic Disorders Editorial: Autonomic Disorders and Their Recognition Anaesthetic Implications and Shy-Drager ... Multiple System Atrophy Articles relating to Parkinson's or Parkinsonisms NIH Researchers Find First Parkinson's Disease Gene Drugs Health touch Online Drug Information Midodrine (ProAmitine) ... Sinemet (Carbidopa; Levodopa) Caregivers A Caregiver's Bill of Rights Caregiving Caregiver Survival Resources Caregiving Support: AARP ... National Family Caregivers Association (NFCA) Hospitals, Studies, and Medical Reports University of Kentucky: Movement Disorders Clinic University Hospitals of Cleveland: Autonomic Laboratory Case study of the Month - Baylor University Case of the Month (A test for students taking neurology) ... GPI-1046 - Nerve Growth (Press Release) Support Groups and Organizations American Autonomic Society Home Page Worldwide Education and Awarness for Movement Disorders (WEMOVE ) National Ataxia Foundation Support Groups Problems Associated with MSA

79. Nature Publishing Group and substantia nigra (striatonigral degeneration) as well as pons, inferior olivesand cerebellar cortex (olivopontocerebellar atrophy), and preganglionic http://www.nature.com/cgi-taf/DynaPage.taf?file=/nm/journal/v7/n2/full/nm0201_13

80. Re: Message (06/12/97) Publication English Unique Identifier 85013697 Order full text for this documentTitle Facial action myoclonus in patients with olivopontocerebellar atrophy. http://www.pcc.com/lists/pedtalk.archive/9706/0097.html

To: Subject: Re: Message From: Date: Thu, 12 Jun 1997 21:41:40 -0500 CC: Really-From: "Dr. Arturo Meneses Pallares" References: Reply-To: I would like opinions on how to approach an infant born with orbicularis oris atrophy. This particular case is now three months old and the deviation of the corner of the mouth remains unchanged. I doubt the possibility I am dealing with facial palsy as the findings are totally localized in the area defined. Eyelids, tongue, etc. appear to move normally. Any suggested workup and differential diagnoses is appreciated. Needless to say the birth history is totally benign. Gonzalo Mantilla Jr., MD. Oficina del Decano USFQ Colegio de Ciencias de la Salud http://www.pcc.com/lists/ " To unsubscribe: mail with with "unsubscribe" in the body of the message. References Re: Message From: (Gonzalo)

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