1. International Pemphigus Foundation; Pemphigus Vulgaris; Pemphigus Foliaceus Information about the conferences, about the organization, fund raising, newsletter, support groups, Category Health Conditions and Diseases Rare Disorders pemphigus......Welcome to the official website of the International pemphigus Foundation. CurrentNews from the International pemphigus Foundation. http://www.pemphigus.org/

Welcome to the official website of the International Pemphigus Foundation. Here you will find information about the auto-immune skin disorders known as pemphigus and pemphigoid . You will also find a great deal of useful information, whether you are living with pemphigus/pemphigoid, caring for someone with pemphigus/pemphigoid, or are simply seeking more information about these relatively rare diseases. The International Pemphigus Foundation Office in Albany, California. The mission of the Foundation is to increase the awareness of pemphigus and pemphigoid among the general public and the medical community; to provide informational and emotional support to pemphigus and pemphigoid patients, their families, friends and care-givers; and to support research into the causes, treatments, and cure for these diseases. One of the important purposes of this site is to provide information and increase awareness about pemphigus. There are many who reach this site in search of diagnostic information, as pemphigus is usually not the first option at which doctors look in making a diagnosis. It is not unusual for patients who experience difficulties getting a proper diagnosis and treatment to find this site, compare and confirm symptoms, and then consult with their doctors. This can lead to a correct diagnosis, leading, in turn, to an appropriate drug regimen to treat and control the disease. Even though pemphigus can have very serious consequences if left untreated, doctors familiar with the condition and the current therapies are generally successful in keeping the symptoms under control, allowing patients to lead quite normal, happy, productive lives.

2. PEMPHIGUS VULGARIS : An informative article by TJ Moriarty about this disorder. http://www.chronicillnet.org/online/lehne.html

PEMPHIGUS VULGARIS : A Diagnostic Chameleon ? by TJ Moriarty OLNews@aol.com Return to the OnLine News Index If you haven't heard of it before, don't feel bad most people haven't. But if you or someone you love has it, the symptoms are unforgettable. "It" is Pemphigus Vulgaris. Its abrasive name draws a fitting mental picture of what it does to its victims . Pemphigus, or commonly referred to as "PV", is an auto-immune blistering disorder of the skin and mucous membranes where those afflicted suffer from burn-like lesions all over their bodies. The sores may never heal in some cases or may not heal for extended periods of time. Some patients can coexist with the disease for years, while others will die a slow and complicated death. Janet Lehne has it. "Sometimes I feel like I'm a walking open sore, and believe it or not, I actually have a mild case." When she first realized something was wrong in 1983, she thought she was dying from AIDS. The common lesions now known to be associated with AIDS and HIV are very similar to a PV outbreak. "My doctors, in the early eighties, were convinced that I was symptomatic and suffering from an aggressive case of AIDS. It scared the hell out of me. I thought I was a dead person." But then she was told she had one of those unusually rare skin conditions that no one really knew much about. "What is PV?" would be one of the obscure, extra-credit questions for medical students of dermatology. She says her scalp literally tears. Her gums bleed and blister before disintegrating. Janet says PV is usually recognized by its slow-progression of infections in the mouth.

3. Pemphigus.com: Information On Types Of Pemphigus, Vulagris, Foliaceus, Paraneopl Healthcare professionals and scientists have carefully prepared this ALtruis Biomedical Networkaffiliated site, intended for informational purposes only. There are three main types of pemphigus pemphigus vulgaris, pemphigus foliaceus and paraneoplastic pemphigus. http://www.pemphigus.com/

Healthcare professionals and scientists have carefully prepared this ALtruis Biomedical Network-affiliated site, intended for informational purposes only Partners: Pemphigus vulgaris Pemphigus foliaceus Paraneoplastic pemphigus Pemphigus Pemphigus describes a blistering condition of the skin caused by the attack of antibodies of certain proteins on the surface of skin cells. This attack interferes with the ability of the skin cells to bind to each other. The immune system normally functions to protect us against foreign invaders, but when it erroneously attacks a component of "self" an autoimmune disease can occur. (Other autoimmune disease include rheumatoid arthritis, lupus, multiple sclerosis and myasthenia gravis) There are three main types of pemphigus: pemphigus vulgaris pemphigus foliaceus and paraneoplastic pemphigus high blood pressure heart failure and various kidney Pemphigus vulgaris (PV) is the most common form. It is a relatively rare disease, affecting approximately 1 in 100,000 people. The lesions commonly manifest in people from 40 to 60 years of age. PV usually begins as blisters in the mouth. Inflammation or erosions may also be present in the lining of the eye and eyelids, and the membranes of the nose or genital tract. Half of the patients also develop blisters or erosions of the skin, often in the groin, underarm, face, scalp and chest areas. The lesions can cover extensive portions of the body. When the blisters or bullae rupture they leave red erosions surrounded by a crust and scaling skin.

4. Pemphigus Information about this disease including myths, articles, hints to living with it, links to other resources, testing, treatment and natural medicines. http://www.uoregon.edu/~sshapiro/Pemphigus/TableOfContents.html

Pemphigus I am not fighting Pemphigus. I am not battling Pemphigus. Pemphigus is not an invader. It is my own immune system that has become so confused that it is attacking my skin and mucus membranes as if they were invaders. To say I am fighting Pemphigus makes no sense, for that would mean that I am fighting myself. I seek to make peace with myself. To understand why my immune system has become so confused, and to correct it. Toward that end I have gathered this information which has proven helpful in my understanding and healing. It may prove useful to you as well. It is my goal to heal my body, mind and spirit, not to suppress or turn off my immune system. Update November, 2001 : It has now been over three years since I last took Prednisone or any other medical treatment for pemphigus. I have been choosing my foods according to my blood type for about 4 and 1/2 years. When I was first diagnosed in 1995, I set a goal to be Pemphigus free by 2003 (seven years). It looks like I'm going to reach that goal well ahead of schedule. What I have found that works for me should produce repeatable results, meaning that others who try it should experience the same results. It doesn't cost anything, there are no products, potions or lotions to purchase. It's all completely free. The choice is yours. Please join me on the web site of Peter D'Adamo, the author of

5. Pemphigus Vulgaris http://www.usc.edu/hsc/dental/opath/Cards/PemphigusVulgaris.html

6. Pemphigus Vulgaris FAQ pemphigus Back to previous level pemphigus, Benign Familial Search PUBMED for pemphigus, Benign Familial All Review Therapy Diagnosis http://www.geocities.com/HotSprings/7445

Pemphigus Vulgaris FAQ (Frequently Asked Questions) Pemphigus Vulgaris is a rare auto-immune disease of skin. This is an informational page for the patients and their families and it contains links which they may find useful. It does not contain medical advice. NEW: I am online with Yahoo messenger as pemphigus_faq. This page was last updated on August 12, 2002 by Victor (victorlei at yahoo dot com). Farewell to Susan. "Pemphigus and You" . Her informal and personal approach to guidance and sharing helped many hundreds of Pemphigus patients worldwide. We miss you Susan. The following is Susan's obituary . My sincere sympathy for to her husband Barry and her family. Read more about PEMPHIGUS and YOU Many thanks to Dan Goodwill for contributing  PV patient checklist. Yesterday I was told I have Pemphigus Vulgaris. What is it? If you are new to Pemphigus Vulgaris, here is a good introductory article by TJ Moriarty: Pemphigus Vulgaris: A Diagnostic Chameleon? What causes Pemphigus Vulgaris? Nobody knows. It is known that Pemphigus Vulgaris is

7. Immune Problems - Pemphigus pemphigus. pemphigus foliaceus, pemphigus vulgaris, pemphigus erythematosus and pemphigus vegetans There are several http://www.vetinfo.com/dpemph.html

Please note: The information on our site is for everyone to read.Please use it as often as you like. However, Ask Dr Mike is available only to subscribers of our Vetinfo Digest. Please do not send questions if you are not a subscriber. Please use the search engine or one of the indexes to see if the information you need is already online. Please see Subscriber info for details. Subscriber Info The income from the subscriptions helps defray the cost of maintaining the site and allows us to keep the large amount of information on www.vetinfo.com free to our readers. Pemphigus Pemphigus Pemphigus-cysts on feet Pemphigus treatment Pemphigus in Saluki also see Immune Problems also see Skin Problems Pemphigus Mike Richards, DVM Pemphigus - Cysts on feet in Weimaraner Question: Hello. My name is Stacy and I have a question regarding my dog, who is a 2-year-old purebreed Weimaraner. My vet recently took biopsies of cysts/pustules that have been resistant to antibiotics and that appear on all of four of her paws (underneath her pads). My vet believes that she may have

8. Pemphigus Hub A brief definition of pemphigus, followed by links to overviews, research projects, case studies and images. http://www.healthubs.com/pemphigus

Pemphigus is an autoimmune skin disorder characterized by flaccid bullae that rupture and leave erosions. It occurs in three major types: pemphigus vulgaris, paraneoplastic pemphigus and pemphigus foliaceus. Pemphigus vulgaris from MEDLINEplus Medical Encyclopedia - updated by Michael Lehrer, M.D., Department of Dermatology, University of Pennsylvania Medical Center, Philadelphia, PA. Pemphigus by the American Osteopathic College of Dermatology Pemphigus Vulgaris by University of Southern California Pemphigus, IgA from Dermatology / eMedicine Journal - by Lawrence Chan, MD, Director, Assistant Professor, Department of Dermatology, Section of Immunodermatology, Northwestern University Medical School. Insights into Pathophysiology and Treatment of Pemphigus - by Anne D. Walling, M.D. Pemphigus Research at Johns Hopkins Medicine Research Study in Pemphigus Vulgaris - by Dr. Animesh A. Sinha, M.D., Ph.D., Dept. of Dermatology, Weill Medical College of Cornell University, New York, NY. Pemphigus Vulgaris - by Dr. Heddie Sedano.

9. Blistering Disorders - Pemphigus - DermatologyChannel pemphigus A look at what this is, the causes, symptoms, diagnosis, treatment and prognosis. http://www.dermatologychannel.net/blistering/pemphigus.shtml

Home Search SiteMap Ask the Dr. ... Medical Store advertisement advertisement BLISTERING DISORDERS Overview Epidermolysis Pemphigoid Pemphigus ... FAQs CONDITIONS Acne Alopecia (baldness) Birthmarks Blistering Disorders ... Blood Vessel Disorders Dermatitis (Eczema) Follicle Disorders Fungal Infections Lyme Disease ... Viral Infections RESOURCES Anatomy Clinical Trials Links News Focus ... Videos ABOUT US Healthcommunities.com Pressroom Testimonials Pemphigus of the skin and mucous membranes is a chronic blistering disease most commonly found in middle-aged persons. There are three major types of pemphigus: Vulgaris (literally meaning common) Foliaceus (featuring superficial blisters) Paraneoplastic (associated with some cancers) Pemphigus is an autoimmune disorder in which the skin cells are attacked by the patient's own antibodies (immune proteins). This causes a separation between the layers of skin in which fluid subsequently accumulates, producing blisters. The introduction of corticosteroids in recent decades has turned what often had been a fatal disease into one that can be managed quite well. Causes The etiology of pemphigus is largely unknown, although genetic predisposition is thought to be the cause. An endemic form of pemphigus foliaceus has been identified in certain rural areas of Brazil and may be transmitted by the bite of a black fly. In rare cases, a medication can induce an attack. Such cases almost always resolve after the offending drug is discontinued. In paraneoplastic pemphigus, the skin problem is caused by cancer. The underlying cancer usually is lymphoid (lymphoma or leukemia) in origin. Paraneoplastic pemphigus typically resolves after the cancer has been treated successfully. It also can be associated with benign lymph tumors.

10. PEMPHIGUS The pemphigus complex is a group of rare autoimmune skin diseases of cats. http://www.tica.org/vet/pemphigus.htm

PEMPHIGUS The pemphigus complex is a group of rare autoimmune skin diseases of cats. Autoimmune diseases are disorders within an individual cat wherein the immune system reacts against the body's own cells, resulting in the production of antibodies and "killer' cells that destroy the target tissue. In this situation, the immune systems fails to recognize the involved tissue as "self". Autoimmune diseases can be life-threatening without prompt medical attention. Pemphigus is characterized by production of antibodies against the intercellular cement substance of the skin. Frequently affected areas include the gums, lining of the mouth, nasal region, the facial zone, nails, and surface of the skin. When the pemphigus antibody attacks its target, it triggers a reaction the culmulates in the destruction of cell-to-cell connections. The loss of intercellular cohesion leads to the formation of blisters within the affected skin layer. Veterinary treatment of feline pemphigus can be difficult, requiring large doses of glucocorticoids, with or without other, more potent drugs. Side effects can be severe, and close physical and laboratory monitoring of the patient is critical. Often, therapy must be maintained for the life of the animal.

11. What Is Pemphigus? What is pemphigus? Types of pemphigus. There are three main categories of pemphiguspemphigus vulgaris, pemphigus foliaceus, and paraneoplastic pemphigus,. http://www.pemphigus.org/whatisgus.html

What is Pemphigus? General Information Diagnosis Treatment New Patient Checklist ... Articles General Information Pemphigus is a group of rare autimmune blistering diseases of the skin and/or mucous membranes. When auto-antibodies attack desmogliens, the cells become separated from each other. The skin virtually becomes unglued. This causes burn-like lesions or blisters that do not heal. In some cases, these blisters can cover a significant area of the skin. Diagnosis Because it is rare, pemphigus is often the last disease considered during diagnosis. Consult a dermatologist if there are any persistent skin or mouth lesions. Early diagnosis may permit successful treatment with only low levels of medication. There are three criteria that must be met for a definite diagnosis: Proper clinical presentation Lesion biopsy Direct immunoflourescence In addition to the above, another diagnostic test that may be used is called indirect immunofluorescence or antibody titer test. This measures desmoglein autoantibodies in the blood serum. It may be used to obtain a more complete understanding of the course of the disease. In addition, a serum assay for desmoglein antibodies, known as ELISA, is also avaiable. It is the most accurate but, unfortunately, is not available in all clinical labs. Click here for a checklist of items for newly diagnosed patients to discuss with a physician.

12. Hailey Hailey Disease (Familial Benign Chronic Pemphigus) British Association of Dermatologists information sheet describing the symptoms and management of this inherited skin condition. http://www.bad.org.uk/patients/skin_disorders/hailey/

13. Pemphigus - Definition pemphigus and Autoimmune Disease. Pictures. Summarized Definition of pemphigus. FullBody. Before and After. Summarized Definition of pemphigus. top. http://www.uoregon.edu/~sshapiro/Pemphigus/DefinePemphigusAndAutoImmuneDisease.h

Pemphigus and Autoimmune Disease Pictures Summarized Definition of Pemphigus Development of the Term Pemphigus Similarities to other diseases ... Home Pictures top Dermatology Department: University of Iowa Dermatology Online Atlas Full Body ... Before and After Summarized Definition of Pemphigus top Pemphigus is an autoimmune skin disorder characterized by blistering of the skin and mucous membrane. There are several types of Pemphigus, notably Pemphigus Vulgaris (PV), Pemphigus Foliaceous (PF) and Pemphigus Vegetans (Pvs). Pemphigus is Latin for "Blistering Skin." Pemphigus involves blistering of the outer (epidermal) layer of the skin and mucous membrane. It is an autoimmune disorder where the immune system produces antibodies against specific proteins in the skin and mucous membrane. These antibodies produce a reaction that leads to a separation of epidermal cells (acantholysis). The exact cause of the development of antibodies against the body's own tissues (autoantibodies) is unknown. A few cases have occurred from reactions to medications, including penicillamine and captopril. More than 95% of people with pemphigus have specific HLA antigens. Pemphigus is rare. It occurs almost exclusively in middle-aged or older people, of all races and ethnic groups. About one-half of the cases of pemphigus vulgaris begin with blisters in the mouth, followed by skin blisters. The blisters (bullae) are relatively asymptomatic, but the lesions become widespread and complications develop rapidly and may be debilitating or fatal.

14. Pemphigus.com: Products pemphigus.com. Products skininformation Skin-Disease.com skin cancerWound-Healing.net Click to Visit Healthcare professionals and http://www.pemphigus.com/products.html

Healthcare professionals and scientists have carefully prepared this ALtruis Biomedical Network-affiliated site, intended for informational purposes only Partners: Products DermArray by IntegriDerm- The first DNA Microarray System for Dermatology Research. IntegriDerm also provides custom service projects. More listings coming soon. See our Advertising Information to advertise here. Back Advertising Information ABN Legal Information ... Trademark Information

15. Canine Pemphigus Vulgaris The present report describes a case of canine pemphigus vulgaris.Some points Página principal Canine pemphigus vulgaris. J Rejas http://www.geocities.com/CollegePark/Field/5413/pemphigus.htm

Canine pemphigus vulgaris Autoimmune mediated skin diseases can be classified in two major groups, bullous processes and non-bullous ones (Carlotti 1989, Halliwell and Gorman 1989), including the first group the pemphigus complex -pemphigus vulgaris, pemphigus foliaceus, pemphigus erythematosus and pemphigus vegetans- and the bullous pemphigoid. According to Muller and others (1989) canine and feline pemphigus represented about 0.3% of the skin diseases observed at the New York State College of Veterinary Medicine being consequently uncommon in domestic animals. The present report describes a case of canine pemphigus vulgaris. Some points of the difficulty for the practitioner to get a definitive diagnosis in autoimmune skin diseases, and its possible treatment are discussed. Pododermatitis Pinna: crusts Case report The dog was a female spanish mastiff aged three years, weighing 45 kg. Her owner had observed that she was apathetic and anorectic one week ago, and that she had non-pruritic skin lesions. Skin lesions included escoriations, pustules, most of them broken, appearing consequently epidermal collarettes and yellowish crusts; occasionally, there were some vesicle among the lesions mentioned above. In oral mucosa it was observed some vesicle localized on lips, without any other lesions.

16. P - Pemphigus Encyclopedia of Canine Veterinary Medical Information pemphigus. pemphigusfoliaceus is the most common of these diseases in the dog. http://www.vetinfo.com/dencyclopedia/depemphigus.html

Vetinfo Canine Encyclopedia Feline Encyclopedia VetInfo Digest ... Your Turn Encyclopedia of Canine Veterinary Medical Information Pemphigus Back Vetinfo Canine Encyclopedia Feline Encyclopedia ... Links Last edited The entire content of the vetinfo.com website is and has been provided by Dr Michael Richards who is a veterinarian. We have discontinued the ask Dr Mike question and answer section of our website at this time. Comments or information about our website, feedback, art info, broken links, spelling errors or help finding things on the site or anything else- e-mail Michal Justis E-mail for www. vetinfo.com is answered by Michal Justis, who is not a veterinarian (but is a Lady). The entire content of the vetinfo.com website is and has been provided by Dr Michael Richards who is a veterinarian. We have discontinued the ask Dr Mike question and answer section of our website at this time. This page is authored by Dr Michael Richards, DVM and produced by TierCom, Inc. Opinions expressed are those of Dr. Richards.

17. PEMPHIGUS And YOU pemphigus and YOU By helping each other we keep hope alive a curewill be found. pemphigus and YOU By helping each other we http://www.expage.com/pemphigus

PEMPHIGUS and YOU "By helping each other...we keep hope alive a cure will be found" My wife, Susan Maizner, has died from an illness unrelated to Pemphigus. I will continue to send the newsletters and answer your questions. Thank you...Barry Maizner I invite you to add this email address into your online address book for posting to PEMPHIGUS and YOU. pemphigusandu@earthlink.net This new Pemphigus/Pemphigoid Q and A is not affiliated in any way with or sanctioned by the National Pemphigus Foundation. It will be dedicated to not only giving support to those with Pemphigus and Pemphigoid, but questions will be personally and discreetly answered to help those who need help in fighting these devastating diseases. Suggestions and answers will be given in a relaxed, non stressful environment with plenty of guidance in an organized fashion. You will save time by not having to wait for an answer or have to wade through numerous posts not having to do with Pemphigus/Pemphigoid. You will be able to ask me for guidance regarding Pemphigus/Pemphigoid questions you may have and in doing so learn some of the time-tested ways to discuss your particular case with your doctors. I have no medical training, but I can share much needed information for dealing with various medications and treatments and advice to help newly diagnosed find the best help and care they need right away ...and enable long-time patients and caregivers to speak with their personal doctors with confidence. I will not be telling you how to treat your disease.....just providing guidance.

18. What Is PEMPHIGUS? What is pemphigus? By helping each other we keep hope alive a curewill be found. What is pemphigus? By helping each other http://www.expage.com/pemphigus2

What is PEMPHIGUS? "By helping each other...we keep hope alive a cure will be found" Pemphigus is an autoimmune disease. Pemphigus is not contagious. The name Pemphigus stems from the Greek "pemphix" which means "blister". Pemphigus is the general term which refers to a variety of chronic bullous diseases. Lesions that present themselves in this condition are bulla, which is a large vesicle often filled with serum and sometimes blood. These bullae can appear on normal skin and mucous membranes causing pain in the mouth and/or itching on the skin. Pemphigus is a very rare disease and can be hard to diagnose, as it resembles many other dermatological conditions such as lichen planus. The major subsets of Pemphigus are Pemphigus Vulgaris, Pemphigus Foliaceus and Paraneoplastic Pemphigus. There are variants of PV and PF. The most common form of Pemphigus is a serious condition, Pemphigus Vulgaris. With PV, men and women are equally affected and although it usually occurs in patients between the fourth and sixth decade of life, younger people and children can get PV. It is now clearly established that the disease affects individuals with a genetic predisposition; and, although the disease affects every race and population, the two genes that predispose to the development of pemphigus are found with higher prevalence in individuals of eastern European Jewish families and in patients from northern India and Asia. It is also rare to find close relatives with Pemphigus. Before the discovery of potent anti-inflammatory drugs, like prednisone, Pemphigus Vulgaris (PV) usually was fatal within a few years from onset.

19. Pemphigus Vulgaris 1 Dept. of Dermatology University of Iowa College of Medicine. pemphigus Vulgaris.Select histology images from the DermPathTutor - Image Index page. http://tray.dermatology.uiowa.edu/PemVul01.htm

Dept. of Dermatology - University of Iowa College of Medicine Pemphigus Vulgaris Select histology images from the DermPathTutor - Image Index page. Return to Image Index page. Return to Image Index page. Return to Dermatology's Home page. September, 1995

20. Pemphigus Foliaceous 2 Dept. of Dermatology University of Iowa College of Medicine. pemphigus Foliaceous- Back. Select histology images from the DermPathTutor - Image Index page. http://tray.dermatology.uiowa.edu/PemFol02.htm

Dept. of Dermatology - University of Iowa College of Medicine Pemphigus Foliaceous - Back Select histology images from the DermPathTutor - Image Index page. Return to Image Index page. Return to Image Index page. Return to Dermatology's Home page. September, 1995

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