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         Pemphigus:     more books (52)
  1. Pemphigus: Webster's Timeline History, 1791 - 2007 by Icon Group International, 2009-06-06
  2. Pemphigus Vulgaris - A Medical Dictionary, Bibliography, and Annotated Research Guide to Internet References by ICON Health Publications, 2004-12-06
  3. Der Pemphigus: Und Die Essentielle Schrumpfung Der Bindehaut Des Auges (1900) (German Edition) by Ernst Franke, 2010-02-23
  4. Pemphigus - A Medical Dictionary, Bibliography, and Annotated Research Guide to Internet References by ICON Health Publications, 2004-12-06
  5. Pemphigus Vulgaris
  6. Options exist for pemphigus diagnosis, treatment.(Dermatologic Therapy)(Disease/Disorder overview): An article from: Skin & Allergy News by John R. Bell, 2007-02-01
  7. Update on pemphigus treatment: present and future.(NEWS, VIEWS, AND REVIEWS): An article from: Journal of Drugs in Dermatology by Isaac Brownell, 2007-12-01
  8. PEMPHIGUS.(Brief Article): An article from: Southern Medical Journal
  9. IVIG therapy tops ten treatment option list: second-line TX for pemphigus.(Dermatologic Therapy)(intravenous immunoglobulin ): An article from: Skin & Allergy News by Kate Johnson, 2004-01-01
  10. 5-year data support rituximab for pemphigus.(NEWS): An article from: Skin & Allergy News by Bruce Jancin, 2009-10-01
  11. CASE OF THE MONTH.(pemphigus vulgaris)(Brief Article): An article from: Skin & Allergy News by Doug Brunk, 2001-08-01
  12. Maladies Inflammatires De La Peau. Monographie Der Pemphigus En Général, En Particulier Et De Son Traitement (French Edition) by Hassan Mahmoud, 2010-09-30
  13. Autosensitization in pemphigus and bullous pemphigoid, by Ernst H Beutner, 1970
  14. The efficacy and safety of rituximab in refractory pemphigus: a review of case reports.: An article from: Journal of Drugs in Dermatology by Kattie J. Allen, Stephen E. Wolverton, 2007-09-01

81. Pemphigus
Goto pemphigus Hartig, 1839 pemphigus borealis Tullgren, 1909 pemphigus bursarius(Linnaeus, 1758) Salaattikirva pemphigus saliciradicis (Börner, 1950) 4.
http://www.funet.fi/pub/sci/bio/life/insecta/homoptera/aphidodea/aphidoidea/pemp
Life Insecta Homoptera Aphidodea ... Pemphiginae
prev next Scientific names Finnish names English names All Thecabius Geoica Pemphigus pemphigus ... pemphigus Goto:
Pemphigus Hartig, 1839
Pemphigus borealis Tullgren, 1909
Pemphigus bursarius (Linnaeus, 1758)
Salaattikirva
Pemphigus populinigrae (Schrank, 1801)
filaginis (Boyer de Fonscolombe, 1841)
Pemphigus saliciradicis (Börner, 1950)

If you have corrections, comments or information to add into these pages, just send mail to Markku Savela
. Keep in mind that the taxononic information is copied from various sources, and may include many inaccuracies. Expert help is welcome.

82. Pemphigus Vulgaris
pemphigus Vulgaris. The mouth is the only site of involvement in half of all casesof pemphigus, and is the initial site of presentation in almost 3/4 of cases.
http://www.maxillofacialcenter.com/BondBook/mucosa/pv.html
Pemphigus Vulgaris
Quick Summary
Introduction

References

Photos
...
Prognosis

Extensive, irregular blisters of the retromolar and buccal area broken but still retain their epithelial covers.
Quick Review for Patients
Top of This Page Introduction Note: click on underlined words for more detail or photos. The most serious of the bullous diseases affecting the oral mucosa is pemphigus vulgaris , a life-threatening autoimmune disorder of skin and mucous membranes. It is relatively rare but shows an increased frequency in Ashkenazi Jews. The mouth is the only site of involvement in half of all cases of pemphigus, and is the initial site of presentation in almost 3/4 of cases. An association between pemphigus vulgaris, myasthenia gravis and thymoma has been reported, and a variety of drugs have been implicated in its induction, especially penicillamine, phenylbutazone, rifampin and captopril, although most cases are idiopathic. It is also known to occur in association with a variety of internal malignancies ( paraneoplastic pemphigus Patients with pemphigus vulgaris produce IgG autoantibodies to desmoglein 3 (the "PV antigen"), a transmembrane glycoprotein which mediates cell adhesion. Although the exact mechanism is unclear, autoantibodies theoretically produce an allosteric change in the desmoglein, impairing its adhesive abilities, and increase active plasmin in the area, producing cell degradation and acantholysis. Complement may be actively involved in this process.

83. Pemphigus
m. pemphigus. I am not fighting pemphigus. I am not battling pemphigus.pemphigus is not an invader. Moriarty. pemphigus Vulgaris
http://www.findhealer.com/link/pemphigus.php3
M y H o l i s t i c . c o m F i n d H e a l e r . c o m
Pemphigus
I am not fighting Pemphigus. I am not battling Pemphigus. Pemphigus is not an invader. It is my own immune system that has become so confused that it is attacking my skin and mucus membranes as if they were invaders. To say I am fighting Pemphigus makes no sense, for that would mean that I am fighting myself. I seek to make peace with myself. To understand why my immune system has become so confused, and to correct it. Steve Shapiro
Articles
Sites
Pemphigus
Steve Shapiro's site about his experience with pemphigus
  • National Pemphi ... gus Foundation - non-profit organization promoting education, referrals and support to those suffering from Pemphi gus and their care-givers.
  • FAQ - Pemphi gus Vulgaris
    Pemphigus, Pemphigus Vulgaris, autoimmune disease, FAQ, support group, mailing list - rare auto-immune disease of skin.
  • Pemphi gus Vulgaris: A Diagnostic Chameleon - paper by TJ Moriarty.
  • Pemphi gus Vulgaris
  • Home Products Home ... contact findhealer.com
    Telstar Innovations
    4734 Topeka Ave
    Oakford, PA 19053

    84. Pemphigus
    pemphigus Vulgaris. pemphigus vulgaris (PV) is one of a group of chronic, relapsingautoimmune diseases causing blistering of the skin and mucosal membranes.
    http://www.skincarecampaign.org/directory/pemphigus.htm

    85. Veterinary Immunology, VEM5110B Pemphigus
    Figure 3 Clefts within epithelium at the base of epidermis with cellularinfiltration. pemphigus Vulgaris. Cat. pemphigus Foliaceous. Cat.
    http://www.vetmed.ufl.edu/path/teach/vem5110b/pemphigus.htm
    Veterinary Immunology
    VEM 5110B Pemphigus Vulgaris
    • Autoantibodies to desmoglein-3 of desmosomes Lesions at mid to lower epidermis
    Phemphigus Follaceous
    • Autoantibodies to desmoglein-1 of desmosomes Lesions ot upper epidermis Phemphigus erythematosis
    Bullous Pemphigoid
    • Autoantibodies to desmoplakins of hemidesmosomes Lesions at lower epidermins to immediately above basement membrane (subepidermis)
    Normal Squamous Epithelium
    Figure 1

    Figure 2

    Figure 3

    Pemphigus Vulgaris Cat
    Figure 4

    Figure 5

    Figure 6
    Ulcerative glossitis
    Figure 7
    Figure 8 Ulcerations of the back Dog Figure 9a Erosive lesions inguinal region and scrotum of a Cardigan Corgi dog.

    86. Pemphigus Vulgaris In A Patient With Human Immunodeficiency Virus Infection
    Abstracts. pemphigus vulgaris in a patient with Human ImmunodeficiencyVirus infection Hodgson TA1*, Fidler S2, Speight P1, Porter SR1.
    http://www.hivdent.org/kabst/kabstrpoj1.htm
    The 4th International Workshop on Oral Manifestations of HIV Infection Abstracts Pemphigus vulgaris in a patient with Human Immunodeficiency Virus infection
    Hodgson TA1*, Fidler S2, Speight P1, Porter SR1. 1Eastman Dental Institute, University College London, UK; 2St Mary's Hospital, London, UK. Introduction
    : The frequency and spectrum of mucocutaneous manifestations associated with Human Immunodeficiency Virus (HIV) infection increases with clinical and immunological deterioration. In contrast autoimmune-mediated disorders tend to improve with HIV disease progression.
    The present report details an HIV-infected patient who developed pemphigus vulgaris in the absence of any HIV-related clinical disease. Case report : A 29 year old HIV-infected male (CD4 count 760 mm3 (Chiron 3) and viral load 26 000) presented to the Oral Medicine unit of the Eastman Dental Institute for Oral Health Care Sciences with a six month history of recurrent oropharyngeal ulceration. He had no associated cutaneous, ocular or gastrointestinal disease. Topical corticosteroids (triamcinolone acetonide and hydrocortisone hemisuccinate) had had little effect. Thalidomide had caused an initial marked clinical improvement, but despite continued therapy his oral ulceration soon recurred. Clinical examination revealed multiple irregular lesions affecting the soft palate, lateral borders of the tongue and buccal mucosa. Histopathological examination of peri-ulcer tissue was consistent with pemphigus vulgaris. Circulating IgG antibodies to intraepithelial components were detected. Initial disease control was obtained with deflazacort followed by the use of topical betamethasone sodium phosphate. A marked deterioration in the oral pemphigus associated with a severe pneumococcal lower respiratory tract infection was treated with deflazacort, and remission of the oral disease was then achieved with deflazacort and azathioprine.

    87. Health Library - Pemphigus
    pemphigus. Synonyms Disorder Subdivisions General Discussion Resources Thelocation and type of blisters vary according to the type of pemphigus.
    http://health_info.nmh.org/Library/HealthGuide/IllnessConditions/topic.asp?hwid=

    88. Apples In The Diet For The Treatment Of Pemphigus Vulgaris: Robert Flitman, M.D.
    Apples in the Diet For the Treatment of pemphigus Vulgaris. Robert FlitmanMarch 17, 1998. The microscopic examination suggested pemphigus.
    http://www.internetweb.com/pemphigus/
    Apples in the Diet For the Treatment of Pemphigus Vulgaris Robert Flitman
    March 17, 1998 The pemphigus disorders are a group of serious and potentially life-threatening diseases characterized by the formation of cutaneous and mucosal blisters. An autoimmune process is believed present which is directed against keratinocyte desmosomal components resulting in a loss of intercellular adhesion (1). Systemic corticosteroids remain the mainstay of therapy for pemphigus, transforming an invariably fatal disease into one whose mortality is now below 10%. Because of the serious side effects of long term corticosteroidal therapy, there have been efforts to use other drugs such as Imuran, Cyclosporin and Dapsone (2). We report a case of pemphigus vulgaris in which reduction of symptoms was obtained by the addition of apples or apple juice to the daily diet. Report of a Case. A 59 year old Caucasian male noted the onset of soreness of the tissues of the mouth of rather sudden onset. The dorsal surface of the tongue as well as the left and right buccal regions were most severely affected. Lesions of these regions appeared in response to the slightest of trauma, for instance the chewing and swallowing of bread with a firm crust. Eating became difficult and a soft diet was adopted. After elimination of common oral cavity problems such as thrush, herpes stomatis and other viral infections, a biopsy of the buccal mucosa was performed and submitted for histopathological examination. The microscopic examination suggested pemphigus. The diagnosis of pemphigus vulgaris was confirmed by immunofluorescent antibody techniques and, later, by the demonstration of the presence of the appropriate circulating antibodies of pemphigus.

    89. Pemphigus
    SUBCATEGORIES. Up. pemphigus pemphigus Vulgaris http//www.chronicillnet.orgAn informative article by TJ Moriarty about this disorder.
    http://www.medlina.com/pemphigus.htm
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    Pemphigus The National Pemphigus Foundation - http://www.pemphigus.org Information about the conferences, about the organization, fund raising, newsletter, support groups, medication, links and a glossary. Pemphigus Vulgaris - http://www.chronicillnet.org An informative article by TJ Moriarty about this disorder. ALtruis Biomedical Network - http://www.pemphigus.com Information on the types, causes and treatments of pemphigus. DermatologyChannel - http://www.dermatologychannel.net Pemphigus: A look at what this is, the causes, symptoms, diagnosis, treatment and prognosis. Pemphigus - http://www.uoregon.edu Information about this disease including myths, articles, hints to living with it, links to other resources, testing, treatment and natural medicines.

    90. Pemphigus
    pemphigus. Tazmin Clingan. The term pemphigus stems from the Greek wordpemphix which means blister (Wojnarowska Briggaman, 1990).
    http://fohweb.uws.edu.au/podiatry/pemphigu.htm
    Pemphigus Tazmin Clingan Age: Middle age - 40-60 years old
    Race: Often individual has a Jewish origin
    Sex: Affects males and females equally
    This presentation will focus on
    Pemphigus Vulgaris Destructive Lesions in P.V
    Clinical Presentation (Schaller, 1994 p.202) Aetiology Pemphigus is an Autoimmune Disease The triggering event in pemphigus is as yet unknown, but what results is the development of blisters which are the result of autoimmunity against the P.V antigen which is a normal component of human skin (Hurley).
    Bransden et al (1997) studied a possible genetic link and predisposition and found that patients with pemphigus vulgaris are genetically linked to two alleles of the HLA subgroup, and circulating antibodies were found in 1st degree relatives of these patients. Sam et al (1997) also acknowledges a familial link where several family members may be involved. Sams et al (1997) states that an external aetiological factor such as insect bites may be responsible for the development of pemphigus. Pathophysiology After autoimmunization (that is when the body reacts against constituents of its own tissues) to the pemphigus vulgaris antigen(a normal component of human skin), autoantibodies bind to stratified epithelial cell membranes

    91. Pemphigus-vulgaris
    pemphigus Vulgaris Network. pemphigus Vulgaris Network. Flat C, 26 St Germans Road. givespeople an opportunity to contact other people with pemphigus vulgaris.
    http://www.ukselfhelp.info/pemphigus-vulgaris/
    Pemphigus Vulgaris Network
    Pemphigus Vulgaris Network Flat C, 26 St Germans Road LONDON SE23 1RJ As the group has no funding please could you enclose a stamped, addressed envelope. The Pemphigus Vulgaris Network offers general support and:
    • provides a forum for people living with all forms of pemphigus and those personally or professionally concerned with it. gives people an opportunity to contact other people with pemphigus vulgaris. helps people find information they need.
    We also support people with cicatricial pemphigoid. The Pemphigus Vulgaris Network is on the British Association of Dermatologists ' register of support groups and is affiliated to the National Pemphigus Foundation of America For more information on pemphigus vulgaris look at the entry for pemphigus vulgaris on the Skin Care Campaign site.
    This page provided by www.ukindex.info . Please visit and make it your home page. Please use the links below so that we can maintain this page as a free internet resource. All links are to UK sites visited and approved by the UK Index Editorial Team.

    92. Pemphigus FAQs & Types
    There is more than one type of pemphigus. Three important pemphigus variants includepemphigus VULGARIS, pemphigus FOLIACEUS, and PARANEOPLASTIC pemphigus.
    http://dermatology.ucsf.edu/autoimmune/pvfaqs&types.htm
    T HREE IMPORTANT VARIANTS In pemphigus, the general process of disease involves the mistaken attack by the immune system (abnormal antibodies) on proteins that bind skin cells tightly together. The destruction of these proteins results in weakening of the skin barrier and formation of blisters. In variants of this disease, specific proteins are targetted at different levels of skin thickness. There is more than one type of pemphigus. Knowing which variant of the disease you have is important because it influences prognosis. Three important pemphigus variants include: PEMPHIGUS VULGARIS, PEMPHIGUS FOLIACEUS, and PARANEOPLASTIC PEMPHIGUS. PEMPHIGUS VULGARIS is the most common form of pemphigus and typically starts as painful sores in the mouth. PEMPHIGUS FOLIACEUS does not usually occur in the mouth. The cell-binding proteins destroyed by these circulating autoimmune antibodies are located in more superficial layers of the skin. The resulting blisters tend to be more fragile and appear first on the face and scalp, then involve the chest and back. PARANEOPLASTIC PEMPHIGUS is extremely rare.

    93. Pemphigus
    pemphigus. Overview by Judy King, In pemphigus the antibodies attempt to reject theanimals own skin attacking the keratinocytes or their cellular components.
    http://www.natural-akita.com/JPTeez/html/pemphigus.html
    Pemphigus Overview
    by Judy King A ccording Chapter 13 of the current Veterinary Dermatology text; Pemphigus Foliaceus is the most common autoimmune skin disease of dogs and cats(Ihrke et al., 1985b; Griffin,1987) This autoimmune skin disease is seen in Akitas more often than any other breed. Autoimmune; meaning when the body produces autoantibodies (antibodies against self) that begin to attack the bodies own cells. In Pemphigus the antibodies attempt to reject the animals own skin attacking the keratinocytes or their cellular components. Clinical signs usually begin as superficial pustules that rapidly rupture, dry and form a yellow-brown crust. When the crust is removed it leaves a moist, erosive ulcerated surface. This symptoms tend to come and go with acute flare-ups being common. Most often the lesions begin on the face at the bridge of the nose and surrounding tissue but the area around the eyes and the ears are also often affected. Less frequently affected are the foot pads and genitals. When the pads are affected, the dog exhibits lameness, pustules are usually absent and the pads appear cracked. Pemphigus may become generalized but can remain localized for up to 3 yrs. if treated early. Remission is possible in some cases. Pemphigus foliaceus affects both males and females. 65% of affected dogs develop the disease by age 5 yrs and usually begin developing signs around age 4 yrs. Other breeds at higher risk are Doberman Pinschers, Newfoundlands, Bearded Collies, Schipperkes, Finnish Spitzes, Dachshunds and Chow Chow.

    94. Genodermatosis Research Foundation
    pemphigus The Other Congenital Skin Disease in Akitas and Chow Chowsby Robert W. Dunstan, DVM, MS, DACVP Kelly M. Credille, DVM, DACVP
    http://www.grfoundation.net/pemphigus.html
    Pemphigus: The "Other" Congenital Skin Disease in Akitas and Chow Chows
    Although sebaceous adenitis is the genodermatosis of Akitas most described by our organization (the GRF), there is a skin disease… that is more common in this breed, and unfortunately, much more devastating. This is so common in Akitas (as well as Chow Chows) that it suggests a strong genetic basis. The disease is autoimmune disease known as pemphigus. It most commonly affects young, adult dogs (2 to 5 years old) where it is characterized by pustules that progress into crusts (scabs) and loss if pigment on the nose leather, the skin of the bridge of the nose, around the eyes, and often, in the ears. In severs cases, the entire body can be involved. By an autoimmune disease, we are referring to a disease in which the body's immune system goes awry. Normally the immune system recognizes only foreign protein such as those that are present in viruses and bacteria. In an autoimmune disease, the body starts to treat one or more of its own proteins as foreign. As a result, the protein incites an inflammatory reaction and is subsequently destroyed. In pemphigus, the protein that is destroyed is essential for holding cells of epidermis (the outer layer of skin) together. As a result of the body's reaction against itself, there are focal regions where pustules form and the cells of the epidermis break away from each other. The term "acantholytic cell" is applied to the cells that fall apart, and they are the microscopic hallmark of the pemphigus diseases.

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