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         Schizencephaly:     more detail
  1. The Official Parent's Sourcebook on Schizencephaly: A Revised and Updated Directory for the Internet Age by ICON Health Publications, 2004-02-13
  2. Schizencephaly: An entry from Thomson Gale's <i>Gale Encyclopedia of Neurological Disorders</i> by Peter, MD Lin, 2005
  3. The Official Parent's Sourcebook On Schizencephaly by Icon Health Publications, 2004

81. EmailPinoy Web Directory
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82. “Open-lip” Schizencephaly
First Previous Next Last Index Text. Slide 14 of 50.
http://www.indyrad.iupui.edu/public/lectures/HTML/BRAIN/sld014.htm

83. Open Directory & Pay Per Click Search Engine: Health/Conditions And Diseases/Gen
LINKS NINDS schizencephaly Information sheet compiled the NationalInstitute of Neurological Disorders and Stroke. http//www.ninds
http://www.searchpixie.com/Health/Conditions_and_Diseases/Genetic_Disorders/Schi
Need Traffic TrafficGiveAway.com Search the Web Home Toolbar LinkManager bookmark ... Genetic Disorders : Schizencephaly LINKS:
  • NINDS: Schizencephaly
    Information sheet compiled the National Institute of Neurological Disorders and Stroke.
    http://www.ninds.nih.gov/health_and_medical/disorders/schizencephaly.htm
  • Pediatric Database
    A definition of schizencephaly, the epidemiology, pathogenesis, clinical features, investigations and management.
    http://www.icondata.com/health/pedbase/files/SCHIZENC.HTM
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84. Health Library - Schizencephaly
Your Health. Search. schizencephaly. Self Help Clearinghouse. SchizKidz Buddies. Online.Email list for persons with schizencephaly
http://yourhealth.stlukesonline.org/Library/HealthGuide/SelfHelp/topic.asp?hwid=

85. CHAPTER_THREE
schizencephaly(Gr.Scheizein to cleave) is a congenital abnormality in which braintissue, usually in the convexity of the hemispheres on one or both sides, is
http://www.akronchildrens.org/neuropathology/CHAPTER_THREE.html
Table of contents
Home
CHAPTER THREE
FETAL AND NEONATAL ISCHEMIA AND STROKE
ASPHYXIA AND HYPOXIC-ISCHEMIC ENCEPHALOPATHY
PERIVENTRICULAR LEUKOMALACIA GERMINAL MATRIX HEMORRHAGE BILIRUBIN ENCEPHALOPATHY
ASPHYXIA AND HYPOXIC-ISCHEMIC ENCEPHALOPATHY
In adults, the brain is about two percent of body weight and receives about fifteen percent of the cardiac output. In term babies, it is ten percent of body weight and uses energy not only to maintain electrical activity but also for growth. Thus, the neonatal brain is even more critically dependent on perfusion and oxygenation . Hypoxic-ischemic encephalopathy (HIE) in the perinatal period has many causes. Placental pathology can impair the exchange of gases across the placenta prenatally. During labor, placental abruptio and cord accidents impair fetal perfusion and oxygenation. The effects of HIE can be compounded by traumatic lesions caused by compression of the fetal head and hyperextension of the fetal neck. Postnatally, hyaline membrane disease, persistent fetal circulation, and congenital heart disease impair oxygenation, and heart failure and shock impair cerebral perfusion. Blood loss from intraventricular hemorrhage, subcapsular hematomas of the liver and other causes may be significant. Examination of the placenta is crucial in order to determine the cause of perinatal HIE, but even after placental examination, the cause often remains unclear. The nonspecific term

86. Health Library - Schizencephaly
Advanced Search. schizencephaly. Self Help Clearinghouse. Schiz KidzBuddies. Online.Email list for persons with schizencephaly (a
http://www.stjudemedicalcenter.org/Library/HealthGuide/SelfHelp/topic.asp?hwid=s

87. Congenital Brain Disorders
schizencephaly may be present in fifty percent of these cases. Corpuscallosum agenesis may also be seen with this entity. schizencephaly.
http://spinwarp.ucsd.edu/NeuroWeb/Text/br-140.htm
PEDIATRIC NEURORADIOLOGY: CONGENITAL DISORDERS OF THE BRAIN WADE H. WONG, D.O. Embryology Congenital disorders of the brain and spine are extremely complex and are best studied by correlating with the embryological development. Stage 1: Dorsal Induction: Formation and Closure of the Neural Tube
    Weeks 3 - 4
    Three phases: Neurulation, canalization, retrogressive differentiation
    Failure: Anencephaly
    Cephalocele
    Chiari
    Spinal dysraphism

Stage 2: Ventral Induction: Formation of the Brain Segments and Face
    Weeks 5-10
    Three vesicles (prosencephalon, mesencephalon, and rhombencephalon) form the cerebrum, mid-brain, cerebellum, and lower brain stem.
    Division into two hemispheres.
    Failure: Holoprosencephalies
    Corpus callosum agenesis
    Dandy Walker
    Facial anomalies

Stage 3: Migration and Histogenesis
Neuronal migration from germinal matrix to the cortex.
Cellular differentiation.
Months 2-5.
Disorders: Heterotopias, agyria-pachyria, polymicrogyria, vascular malformations, teratomas, phakomatosis.

Stage 4: Myelination
Inferior to superior; posterior to anterior.

88. Medicalseek - Search Engine For The Healthcare Industry
FORUMS. Home HealthShop Diet Prescriptions Women Men. Conditionsand Diseases Genetic Disorders schizencephaly. Conditions and
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  • NINDS: Schizencephaly
    Information sheet compiled the National Institute of Neurological Disorders and Stroke.
    ninds.nih.gov/health_and_medical/disord...
    Pediatric Database

    A definition of schizencephaly, the epidemiology, pathogenesis, clinical features, investigations and management.
    icondata.com/health/pedbase/files/SCHIZ...
CATEGORIES ADD A LINK ADVERTISE CONTACT US ... FORUMS

89. Emx
Boncinelli's group found that several cases of schizencephaly, a human congenitaldisorder implying defects in the development of the cerebral cortex, are
http://www.iephb.nw.ru/labs/lab38/spirov/hox_pro/emx.html
Homeobox Genes DataBase
Drosophila/Vertebrate Genes in Development:
empty-spiracles family (Emx1 and 2)
Definition:
Homeobox genes Emx1 and 2 belongs to empty-spiracles family. Their expression pattern was studied in mouse embryos by means of in situ hybridization. All of them appear to be expressed in the brain of midgestation mouse embryos with characteristic patterns. In order to understand the role of Emx and Otx genes in the developing cerebral cortex of mice, the temporal profile of their expression between E9 and E17 was analysed by Boncinelli with co-workers. Emx2 expression appears to be confined to the ventricular germinal zone, which suggests that this gene plays a role in cortical neurogenesis. On the contrary, Emx1 is expressed in essentially all cortical neurons, whether proliferating, migrating, differentiating or differentiated. Boncinelli's group found that several cases of schizencephaly, a human congenital disorder implying defects in the development of the cerebral cortex, are associated with mutations in the EMX2 gene.
Expression Patterns:
Brain Patterning
Regulatory Regions:
Mutations and Knockouts:
several cases of schizencephaly, a human congenital disorder implying defects in the development of the cerebral cortex, are associated with mutations in the EMX2 gene

90. Virtual Hospital: Radiology Resident Case Of The Week: Schizencephaly
Radiology Resident Case of the Week April 26, 1996. Image 3. Lorenzo Carson,MD Peer Review Status Internally Peer Reviewed. Previous Page Title Page.
http://www.vh.org/pediatric/provider/radiology/PedRadSecTF/042696/BrainMR3.html
Radiology Resident Case of the Week: April 26, 1996
Image 3
Lorenzo Carson, M.D.
Peer Review Status: Internally Peer Reviewed Previous Page Title Page See related Provider Textbooks about Radiology See related Provider Topics Diagnostic Imaging Procedures and Therapies or Radiology See related Patient Textbooks about Radiology See related Patient Topics Diagnostic Imaging Procedures and Therapies or Radiology Virtual Children's Hospital Home Virtual Hospital Home Site Map ... UI Health Care Home http://www.vh.org/pediatric/provider/radiology/PedRadSecTF/042696/BrainMR3.html

91. Topica Email List Directory
Click Here! List Directory, Lists Help.
http://www.topica.com/dir/?cid=5333

92. Familiaalinen Skitsenkefalia
Kehitysvammahuollon tietopankki. Aivorakoiluhuokoistuma, CP ja kehitysvamma.Skitsenkefalia. Skitsenkefalia eli aivorakoiluhuokoistuma
http://www.saunalahti.fi/kup/syndroma/aivorako.htm
Kehitysvammahuollon tietopankki
Aivorakoiluhuokoistuma, CP- ja kehitysvamma
Skitsenkefalia
Skitsenkefalia eli aivorakoiluhuokoistuma on aivoepämuodostuma, jota luonnehtii isoaivojen harmaan aineen laskostuminen aivopuoliskojen halkion ympärille lähellä primääristä (historiallisesti ensin kehittynyttä) aivokudosta. Hermosolujen siirtymishäiriön aiheuttama aivorakoiluhuokoistuma on perinnöllinen sairaus, jonka oireita ovat kehitysvammaisuus ja CP-vammaisuus . Skitsenkefalian taustalla olevaa geenivirhettä ei tunneta. Lisätietoja: Victor A. McKusick: Schizencephaly, Familial, OMIM Database
NINDS Schizencephaly Information Page

SCHIZ KIDZ BUDDIES

Schizencephaly, Medical College of Wisconsin
Kari Viitapohja 20.5.2000. 21.4.2002
Kehitysvammaisten Uudenmaan tukipiiri ry. Kehitysvammahuollon tietopankki

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