1. THE MERCK MANUAL, Sec. 14, Ch. 179, Disorders Of Movement are hereditary; others are sporadic. spinocerebellar degenerations can be broadly categorized as predominantly spinal http://www.merck.com/pubs/mmanual/section14/chapter179/179g.htm

This Publication Is Searchable The Merck Manual of Diagnosis and Therapy Section 14. Neurologic Disorders Chapter 179. Disorders Of Movement Topics [General] Tremor Dyskinesias Drug-Induced Movement Disorders ... Idiopathic Orthostatic Hypotension And Shy-Drager Syndrome Cerebellar And Spinocerebellar Disorders Disorders of the cerebellum and its inflow or outflow pathways produce deficits in the rate, range, and force of movement. Anatomically, the cerebellum has three subdivisions. The archicerebellum (vestibulocerebellum) comprises the flocculonodular lobe, helps maintain equilibrium and coordinate eye-head-neck movements, and is closely interconnected with the vestibular nuclei. The midline vermis (paleocerebellum) helps coordinate movement of the trunk and legs. Vermis lesions result in abnormalities of stance and gait. The lateral hemispheres, which make up the neocerebellum, control ballistic and finely coordinated limb movements, predominantly of the arms. Signs of cerebellar disease are listed in Table 179-3.

2. 1Up Health > Health Links Directory > Conditions And Diseases: Neurological Diso Health Health Directory Conditions and Diseases Neurological Disorders Spinal Cord spinocerebellar degenerations (5) http://www.1uphealth.com/links/spinal-cord-spinocerebellar-degenerations.html

Home Contact Us Privacy Caring For Your Well Being Alternative Medicine Clinical Trials Health News Poisons ... Health Topics A-Z Search 1Up Health Health Directory Addictions Alternative Animal ... Weight Loss By Demography Child Health Teen Health Men's Health Women's Health ... Spinal Cord : Spinocerebellar Degenerations Description Categories Ataxia Friedreich Ataxia Machado-Joseph Olivopontocerebellar Atrophy Sites Marinesco-Sjogren Syndrome Information and a support group for families affected with this syndrome, a rare genetic disorder characterized by ataxia, cataracts, very small stature, and mental retardation. Help build the largest human-edited directory on the web. Submit a Site Open Directory Project Become an Editor Parts of the directory made available on 1UpHealth have been modified. External Web site links provided on this site are meant for convenience and for informational purposes only; they do not constitute an endorsement. Search: The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed physician should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only they do not constitute endorsements of those other sites. Home Contact Us Privacy Links Directory

3. Olivopontocerebellar Atrophy Cerebellar degenerations (also called spinocerebellar degenerations) can either be sporadic or heredofamilial. http://www.medhelp.org/perl6/neuro/archive/15346.html

Advertisement Welcome to Med Help International A not-for-profit organization Questions in The Neurology Forum are being answered by doctors from The Cleveland Clinic , consistently ranked one of the best hospitals in America. Subject: Olivopontocerebellar Atrophy Topic Area: Neurology - General Forum: The Neurology and Neurosurgery Forum Question Posted By: Sandy Clarke on Monday, August 18, 1997 : : Hello: : : Can you tell me what diagnostic test currently are used to diagnose and confirm OPCA? : : Thank you very much!! : Dear Dave: : Cerebellar degenerations (also called spinocerebellar degenerations) can either be sporadic or heredofamilial. Heredofamilial cerebellar degenerations can be either autosomal dominant (various types termed spinocerebellar ataxia = SCA 1 - 7, DRPLA, Machado-Joseph disease, etc) or autosomal recessive (Friedreich's ataxia, and some other rare types). : The syndrome of progressive ataxia (imbalance of gait, incoordination of hands, slurred speech), in association with some other characteristic abnormalities (peripheral neuropathy, optic atrophy, retinitis pigmentosa, dementia, corticospinal dysfunction, oculomotor dysfunction, etc) is seen with heredofamilial forms. Ataxia is associated with autonomic dysfunction and/or parkinsonian features in sporadic cases. Either sporadic or autosomal dominant forms of cerebellar degeneration can be associated with atrophy of the cerebellum, pons and inferior olives, either on MRI, or at autopsy. Hence, OPCA (olivopontocerebellar atrophy) is used as a descriptive term for these disorders.

4. BioMed Central | Abstract | Spinocerebellar Degenerations: An Update Report spinocerebellar degenerations An Update Susan L Perlman MD Department ofNeurology, 300 UCLA Medical Plaza Suite B200, UCLA School of Medicine, Los http://www.biomedcentral.com/1528-4042/2/331/abstract

Welcome guest user home journals A-Z journals by subject advanced search ... Issue 4 Viewing options Abstract Full text PDF Other links: E-mail to a friend Download references Post a comment Search PubMed For Perlman SL Report Susan L Perlman MD Department of Neurology, 300 UCLA Medical Plaza Suite B200, UCLA School of Medicine, Los Angeles, CA, 90095, USA Current Neurology and Neuroscience Reports Abstract Over the past decade, the spinocerebellar degenerations have gone from a diverse group of loosely defined phenotypes to a family of diseases with many identifiable genotypes and the promise of gene-specific treatments. The evaluation of the spinocerebellar ataxias has been simplified, and the counseling of patients and families has been enhanced by the growing number of molecular diagnostic tests now available. Management strategies remain symptomatic and focused on rehabilitation, with empirical use of antioxidants based on research in other neuro-genetic diseases. Terms and Conditions Privacy statement Information for advertisers Contact us

5. DIRECTORY.TERADEX.COM - Health/Fitness/Diseases/Neurological Disorders/Spinal Co DIRECTORY / Health/Fitness / Diseases / Neurological Disorders / Spinal Cord / spinocerebellar degenerations (5) http://directory.teradex.com/Health_Fitness/Diseases/Neurological_Disorders/Spin

preloadImages('as_free_x-mail_s','as_anonymous','as_ad-space'); Add your Web Site Add Search to your Site Search for: Search through: Entire site Spinocerebellar Degenerations Friedreich Ataxia DIRECTORY Health/Fitness Diseases ... Marinesco-Sjogren Syndrome - Information and a support group for families affected with this syndrome, a rare genetic disorder characterized by ataxia, cataracts, very small stature, and mental retardation. Submit Premium Listing! $10 for two years Sign Up User Name: Password: Edit in Real Time, Banner Placement Help build the largest human-edited directory on the web. Submit a Site Open Directory Project Become an Editor This site is presented in modified Open Directory form E-Mail: webmaster@teradex.com Aaex Corp.

6. BioMed Central | Full Text | Spinocerebellar Degenerations: An Update Welcome guest user, http://www.biomedcentral.com/1528-4042/2/331

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7. THE MERCK MANUAL, Sec. 14, Ch. 179, Disorders Of Movement subdural hematoma, and degenerative disorders, including striatonigral degenerationand multiple systems atrophy (see spinocerebellar degenerations, below). http://www.merck.com/pubs/mmanual/section14/chapter179/179e.htm

This Publication Is Searchable The Merck Manual of Diagnosis and Therapy Section 14. Neurologic Disorders Chapter 179. Disorders Of Movement Topics [General] Tremor Dyskinesias Drug-Induced Movement Disorders ... Idiopathic Orthostatic Hypotension And Shy-Drager Syndrome Parkinson's Disease (Shaking Palsy) An idiopathic, slowly progressive, degenerative CNS disorder characterized by slow and decreased movement, muscular rigidity, resting tremor, and postural instability. Etiology and Pathophysiology In primary Parkinson's disease, the pigmented neurons of the substantia nigra, locus caeruleus, and other brain stem dopaminergic cell groups are lost. The cause is not known. The loss of substantia nigra neurons, which project to the caudate nucleus and putamen, results in depletion of the neurotransmitter dopamine in these areas. Onset is generally after age 40, with increasing incidence in older age groups. Secondary parkinsonism results from loss of or interference with the action of dopamine in the basal ganglia due to other idiopathic degenerative diseases, drugs, or exogenous toxins. The most common cause of secondary parkinsonism is ingestion of antipsychotic drugs or reserpine, which produce parkinsonism by blocking dopamine receptors. Coadministration of an anticholinergic drug (eg, benztropine 0.2 to 2 mg po tid) or amantadine (100 mg po bid) may ameliorate the resulting symptoms. Less common causes include carbon monoxide or manganese poisoning, hydrocephalus, structural lesions (tumors, infarcts affecting the midbrain or basal ganglia), subdural hematoma, and degenerative disorders, including striatonigral degeneration and multiple systems atrophy (see

8. Spinocerebellar Degenerations http//www.ncbi.nlm.nih.gov/genome/guide/HsChr9.shtml. 9 mutationsDysautonomia Friedreich_ataxia Torsion Dystonia 1 Fanconi_anemia,. http://freesense.free.fr/Diseases/c/393.htm

http://www.ncbi.nlm.nih.gov/genome/guide/HsChr9.shtml 9 mutations Dysautonomia Torsion Dystonia http://www.ncbi.nlm.nih.gov/genome/guide/HsChr14.shtml MA Some diseases associated with chromosome 14 mutations Alzheimer_disease Machado-joseph_disease Spastic Paraplegia 3a See OMIM for additional examples Tropes Web V1.0

9. Classes heredodegenerative disorders, nervous system (31) muscular dystrophies(8); spinocerebellar degenerations (2). metabolism, inborn errors (25) http://freesense.free.fr/Diseases/c/

Retour au texte Choisissez: congenital, hereditary, and neo (136) abnormalities (47) abnormalities, multiple (20) ectodermal dysplasia (2) ... otorhinolaryngologic diseases (2)

10. Re: Re: Olivopontocerebellar Atrophy The Neurology and Neurosurgery Forum ask the doctor medical forum for patients hosted by Med Help Intl. Cerebellar degenerations (also called spinocerebellar degenerations) can either be sporadic or heredofamilial. http://www.medhelp.org/perl6/neuro/archive/15049.html

Advertisement Welcome to Med Help International A not-for-profit organization Questions in The Neurology Forum are being answered by doctors from The Cleveland Clinic , consistently ranked one of the best hospitals in America. Subject: Re: Re: Olivopontocerebellar atrophy Forum: The Neurology and Neurosurgery Forum Topic Area: Ataxia Posted by Dave F on January 11, 1999 at 23:08:29: In Reply to: Re: Olivopontocerebellar atrophy posted by CCF Neurology MD:NT on January 11, 1999 at 20:32:38: : : Hello: : : Can you tell me what diagnostic test currently are used to diagnose and confirm OPCA? : : Thank you very much!! : Dear Dave: : Cerebellar degenerations (also called spinocerebellar degenerations) can either be sporadic or heredofamilial. Heredofamilial cerebellar degenerations can be either autosomal dominant (various types termed spinocerebellar ataxia = SCA 1 - 7, DRPLA, Machado-Joseph disease, etc) or autosomal recessive (Friedreich's ataxia, and some other rare types). : The syndrome of progressive ataxia (imbalance of gait, incoordination of hands, slurred speech), in association with some other characteristic abnormalities (peripheral neuropathy, optic atrophy, retinitis pigmentosa, dementia, corticospinal dysfunction, oculomotor dysfunction, etc) is seen with heredofamilial forms. Ataxia is associated with autonomic dysfunction and/or parkinsonian features in sporadic cases. Either sporadic or autosomal dominant forms of cerebellar degeneration can be associated with atrophy of the cerebellum, pons and inferior olives, either on MRI, or at autopsy. Hence, OPCA (olivopontocerebellar atrophy) is used as a descriptive term for these disorders.

11. Searchalot Directory For Spinocerebellar Degenerations Searchalot, we search a lot, so you don't have too! http://www.searchalot.com/Top/Health/ConditionsandDiseases/NeurologicalDisorders

Home Search News Email Greetings Weather ... Global All the Internet About AltaVista AOL Search Ask Jeeves BBC Search BBC News Business Dictionary Discovery Health Dogpile CheckDomain CNN Corbis eBay Education World Employment Encyclopedia Encarta Excite Fast Search FindLaw FirstGov Google Google Groups Infomine iWon Librarians Index Looksmart Lycos Metacrawler Microsoft Northern Light Open Directory SearchEdu SearchGov Shareware Teoma Thesaurus Thunderstone WayBackMachine Webshots WiseNut Yahoo! Yahoo! Auctions Yahoo! News Yahooligans Zeal Sponsored Links Top Health Conditions and Diseases Neurological Disorders ... Spinal Cord : Spinocerebellar Degenerations Ataxia Friedreich Ataxia Machado-Joseph Olivopontocerebellar Atrophy Related Web Sites Marinesco-Sjogren Syndrome - Information and a support group for families affected with this syndrome, a rare genetic disorder characterized by ataxia, cataracts, very small stature, and mental retardation. All the Internet About AltaVista AOL Search Ask Jeeves BBC Search BBC News Business Dictionary Discovery Health Dogpile CheckDomain CNN Corbis eBay Education World Employment Encyclopedia Encarta Excite Fast Search FindLaw FirstGov Google Google Groups Infomine iWon Librarians Index Looksmart Lycos Metacrawler Microsoft Northern Light Open Directory SearchEdu SearchGov Shareware Teoma Thesaurus Thunderstone WayBackMachine Webshots WiseNut Yahoo!

12. Searchalot Directory For Spinal Cord Myelitis (6). Spinal Muscular Atrophy (11); spinocerebellar degenerations (5); StiffPersonSyndrome (4); Syringomyelia (4); Tabes Dorsalis (2). Related Web Sites. http://www.searchalot.com/Top/Health/ConditionsandDiseases/NeurologicalDisorders

Home Search News Email Greetings Weather ... Global All the Internet About AltaVista AOL Search Ask Jeeves BBC Search BBC News Business Dictionary Discovery Health Dogpile CheckDomain CNN Corbis eBay Education World Employment Encyclopedia Encarta Excite Fast Search FindLaw FirstGov Google Google Groups Infomine iWon Librarians Index Looksmart Lycos Metacrawler Microsoft Northern Light Open Directory SearchEdu SearchGov Shareware Teoma Thesaurus Thunderstone WayBackMachine Webshots WiseNut Yahoo! Yahoo! Auctions Yahoo! News Yahooligans Zeal Sponsored Links Top Health Conditions and Diseases Neurological Disorders : Spinal Cord Amyotrophic Lateral Sclerosis Compression Epidural Abscess Injury ... Tabes Dorsalis Related Web Sites Spinal Injuries Association - Offers a Spinal Chat Room, a Bulletin Board and factsheets for people with spinal injuries, paraplegics, tetraplegics, wheelchair users and walkers. Spinal Cord Arteriovenous Malformations - Support, links and information on spinal cord and other AVMs. Patient-oriented site Related Categories Health: Conditions and Diseases: Musculoskeletal Disorders: Back and Spine All the Internet About AltaVista AOL Search Ask Jeeves BBC Search BBC News Business Dictionary Discovery Health Dogpile CheckDomain CNN Corbis eBay Education World Employment Encyclopedia Encarta Excite Fast Search FindLaw FirstGov Google Google Groups Infomine iWon Librarians Index Looksmart Lycos Metacrawler Microsoft Northern Light Open Directory SearchEdu SearchGov Shareware Teoma Thesaurus Thunderstone WayBackMachine Webshots WiseNut Yahoo!

13. Www.nlm.nih.gov/cgi/mesh/2K/MB_cgi?term=Spinocerebellar+Degenerations Similar pages Replaced Medical Subject Headings Sinus Thrombosis, (P), Sinus Thrombosis, Intracranial. Spinocerebellar Degeneration,(P), spinocerebellar degenerations. StiffMan Syndrome, (P), Stiff-Person Syndrome. http://www.nlm.nih.gov/cgi/mesh/2K/MB_cgi?term=Spinocerebellar Degenerations

14. Conditions And Diseases: Neurological Disorders: Spinal Cord: Spinocerebellar De Information on Conditions and Diseases, Neurological Disorders, Spinal Cord,spinocerebellar degenerations and much more Treasure Coast Health. http://treasurecoasthealth.com/treasurecoasthealth.php/Health/Conditions_and_Dis

Find Doctors on the Treasure Coast Select Specialty Ambulatory Care Anesthesiology Cardiology Dermatology Emergency Medicine Endocrinology Family Practice Gastroenterology Hematology/Oncology Infectious Diseases Internal Medicine Maxillofacial Surgery Neonatology Nephroology Neurology Neurosurgery Obstetrics/Gynecology Ophthalmology Orthopedic Surgery Otolaryngology Pathology Pediatics Physical Medicine Plastic Surgery Podiatry Psychiatry Psychology Pulmonary Radiation Oncology Radiology Rheumatology Surgery Thoracic Surgery Urology Vascular Surgery Select City Sebastian Palm Bay Vero Beach Fort Pierce Okeechobee Port St. Lucie Jensen Beach Stuart Palm City Hobe Sound Loxahatchee MENU Home Doctor Directory Health Resources Women Only ... About Us Conditions and Diseases: Neurological Disorders: Spinal Cord: Spinocerebellar Degenerations Ataxia Friedreich Ataxia Machado-Joseph Olivopontocerebellar Atrophy ... http://www.nutrisystem.com We have helped millions of people lose weight for more than 30 years. Lose up to 10 lbs. in your first month! Marinesco-Sjogren Syndrome - Information and a support group for families affected with this syndrome, a rare genetic disorder characterized by ataxia, cataracts, very small stature, and mental retardation.

15. Conditions And Diseases: Neurological Disorders: Spinal Cord | Treasure Coast He Myelitis@ (6). Spinal Muscular Atrophy@ (11); spinocerebellar degenerations(5); StiffPerson Syndrome@ (4); Syringomyelia@ (4); Tabes Dorsalis (2). http://treasurecoasthealth.com/treasurecoasthealth.php/Health/Conditions_and_Dis

Find Doctors on the Treasure Coast Select Specialty Ambulatory Care Anesthesiology Cardiology Dermatology Emergency Medicine Endocrinology Family Practice Gastroenterology Hematology/Oncology Infectious Diseases Internal Medicine Maxillofacial Surgery Neonatology Nephroology Neurology Neurosurgery Obstetrics/Gynecology Ophthalmology Orthopedic Surgery Otolaryngology Pathology Pediatics Physical Medicine Plastic Surgery Podiatry Psychiatry Psychology Pulmonary Radiation Oncology Radiology Rheumatology Surgery Thoracic Surgery Urology Vascular Surgery Select City Sebastian Palm Bay Vero Beach Fort Pierce Okeechobee Port St. Lucie Jensen Beach Stuart Palm City Hobe Sound Loxahatchee MENU Home Doctor Directory Health Resources Women Only ... About Us Conditions and Diseases: Neurological Disorders: Spinal Cord Amyotrophic Lateral Sclerosis Compression Epidural Abscess Injury ... Tabes Dorsalis See also: Health: Conditions and Diseases: Musculoskeletal Disorders: Back and Spine This category in other languages: Japanese Spanish http://www.nutrisystem.com

16. E-b-5 research is focused on diseases caused by expansions of CAG repeats encoding polyglutaminestretches, which include hereditary spinocerebellar degenerations. http://www.nig.ac.jp/labs/AR98e/E/E-b-5.html

(5) Molecular mechanisms of hereditary neurodegenerative diseases Shoji TSUJI (Niigata University)

17. Volume 108 January - December 1985 Prevalence and pattern of spinocerebellar degenerations in Northeastern Libya.R . Sridharan , K . Radhakrishnan , PP . Ashok and ME . Mousa. Pages 831 - 844. http://www3.oup.co.uk/jnls/supplements/braini/hdb/Volume_108/Issue_04/1080831.sg

Volume 108: January - December 1985 Issue 4: December 1985 Abstract Prevalence and pattern of spinocerebellar degenerations in North-eastern Libya R Sridharan K Radhakrishnan PP Ashok and ME Mousa Pages: Part of the OUP Brain WWW service General Information Click here to register with OUP. This page is maintained by OUP admin Last updated 14 May 97 Part of the OUP Journals World Wide Web service Oxford University Press, 1997

18. Ues: Volume 108: January - December 1985: Issue 4: December 1985 Pages 817 830. Prevalence and pattern of spinocerebellar degenerations in North-easternLibya. R . Sridharan , K . Radhakrishnan , PP . Ashok and ME . Mousa http://www3.oup.co.uk/jnls/supplements/braini/hdb/Volume_108/Issue_04/

Volume 108: January - December 1985 Issue 4: December 1985 Table of Contents Treatment of word retrieval deficits in aphasia. A comparison of two therapy methods D Howard K Patterson S Franklin V Orchard-Lisle and J Morton Pages: Prevalence and pattern of spinocerebellar degenerations in North-eastern Libya R Sridharan K Radhakrishnan PP Ashok and ME Mousa Pages: Acid maltase deficiency in adults CM Wiles PSJ Trend GT Spencer JA Morgan Hughes BD Lake and AD Patrick Pages: Clinical and neuropathological criteria for the diagnosis and staging of diabetic polyneuropathy PJ Dyck JL Karnes J Daube P O'Brien and FJ Service Pages: Retrograde crossed cerebellar atrophy HD Chung Pages: Qualitative and quantitatave morphology of human sural nerve at different ages S Love and JM Jacobs Pages: Predictive ocular motor control in Parkinson's disease C Kennard and AM Bronstein Pages: Congenital centronuclear (myotubular) myopathy: a clinical, pathological and genetic study in eight children JZ Heckmatt CA Scurry D Hodes and V Dubowitz Pages: Illusory movements produced by electrical stimulation of low-threshold muscle afferents from the hand SC Gandevia Pages: Posterior fossa subdural empyema B Williams and DW Morgan Pages: A contribution to the anatomical basis of thalamic amnesia DY von Cramon N Hebel and U Schuri Pages: Autotopagnosia: occurrence in a patient without nominal aphasia and with an intact ability to point to parts of animals and objects JA Ogden Pages: Involvement of the central nervous system in Schistosoma mansoni and Schistosoma haematobium infection. A review

19. Directory :: Look.com spinocerebellar degenerations (5) Other Categories. Ataxia (10) FriedreichAtaxia (4) MachadoJoseph (6) Olivopontocerebellar Atrophy (4) Sites. http://www.look.com/searchroute/directorysearch.asp?p=595030

20. Spinocerebellar Degenerations Website Results :: Linkspider UK spinocerebellar degenerations Websites from the Linkspider UK. SpinocerebellarDegenerations Directory. Complete Results for Spinocerebellar http://www.linkspider.co.uk/Health/ConditionsandDiseases/NeurologicalDisorders/S

Spinocerebellar Degenerations Websites from Linkspider UK Keyword: Spinocerebellar Degenerations Linkspider UK Directory Spinocerebellar Degenerations Search for Directory Tree: Top Health Conditions and Diseases Neurological Disorders ... Spinal Cord : Spinocerebellar Degenerations (5) Add URL Advertise Here! Personalize Amazon ... Marinesco-Sjogren Syndrome - Information and a support group for families affected with this syndrome, a rare genetic disorder characterized by ataxia, cataracts, very small stature, and mental retardation.

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