61. Infectious Diseases - Congenital Syphilis Infectious Diseases. CONGENITAL syphilis. Syphilitic pregnant womenwho have not received therapy may transmit the infection to their http://www.mc.vanderbilt.edu/peds/pidl/infect/congsyph.htm

PIDL Home/ Contents Development Nutrition Acute Illness ... Psychosocial Infectious Diseases CONGENITAL SYPHILIS Syphilitic pregnant women who have not received therapy may transmit the infection to their fetuses at any clinical stage of their disease. 70% of all pregnant women with untreated primary syphilis, 90% of women with secondary syphilis and approximately 30% of women with latent syphilis may transmit the infection to their fetuses. In general the greater the time that has elapsed since the woman's primary or secondary infection the less likely she is to transmit disease to the fetus. At the onset of congenital syphilis, T. pallidum is liberated directly into the circulation of the fetus resulting in widespread dissemination. The outcome of untreated fetal infection is variable. Intrauterine death occurs in an estimated 25% of infections. Perinatal death may occur in an additional 25% of untreated infected babies. The signs and symptoms of congenital syphilis are arbitrarily divided into early manifestations, which appear in the first 2 years of life, and late manifestations. Early congenital syphilis usually has onset between birth and about three months of life, with most cases occurring within the first five weeks of life. The baby with congenital syphilis may appear perfectly normal at birth only to appear later in the newborn period with "septic" syphilis characterized by multi- organ failure.

62. Kipkeepers, Pox And Gleet Vendors: A Rapid History Of Syphilis The History of syphilis. How viewing. RealAudio Kipkeepers, Pox andGleet Vendors A Rapid History of syphilis; RealAudio Osler Quote; http://www.medinfo.ufl.edu/other/histmed/clancy/

Return to History of Medicine Home Page The History of Syphilis How to Use These Slides: This presentation has been enhanced using RealAudio. To hear the audio track you will need to install the RealPlayer available free from www.real.com . To start the program, click on the icon next to slide you wish to view. After a few moments the RealPlayer will begin the audio program at that point. You may also select any slide to view it without audio. Use the controls ( ) to move forward, backward, or return to this index. You may need to adjust the font size of your browser for optimal viewing. Kipkeepers, Pox and Gleet Vendors: A Rapid History of Syphilis Osler Quote Clinical Photos List Manifestations/Organs Primary syphilis ... Tuskegee Study of Untreated Syphilis in the Negro Male, 1932-1972 Author: Neil Clancy M.D. Contact: Dr. Michael Okun / msokun@pol.net Version: Produced by the Office of Medical Informatics 1999 by the University of Florida Location: http://www.medinfo.ufl.edu/other/histmed/clancy/index.html Created: December 9, 1999

63. Syphilis syphilis is a sexually transmitted disease caused by a bacteria (Treponemapallidum). Babies can be born with syphilis as they can http://www.netdoctor.co.uk/diseases/facts/syphilis.htm

The UK's leading independent health website Search NetDoctor NetDoctor.co.uk Home News and features News Newsletter Features Encyclopaedia Diseases Medicines Examinations Health centres Cancer Children's health Depression Erectile dysfunction ... All health centres Discussion and support Discussion forums Support groups Services Ask the doctor Find a hospital NetDoctor on call Search Medline ... Text message services Information About NetDoctor Commercial opportunities NetDoctor.com Syphilis Reviewed by Dr John Pillinger , GP What is syphilis? Syphilis is a sexually transmitted disease caused by a bacteria (Treponema pallidum). Babies can be born with syphilis as they can catch the disease from their mothers in the womb. Syphilis is no longer commonplace in the developed world but it is still widespread in Asia and Africa. Many of the cases of syphilis seen in the UK are contracted in these countries. How is syphilis contracted? Through close sexual contact. From mothers to their babies. What are the signs of syphilis? The first stage of syphilis is contagious and occurs three to six days after contact. Lesions show where the skin has been in contact with the bacteria. The lesions appear as painless red sores (chancre) and are often seen on the penis or the labia or inside the vagina itself. Lesions can also be found in the rectum after anal sex, or in the mouth after oral sex. The lesions will usually disappear after a few weeks. The second stage is contagious and occurs around six weeks or more after the chancre appears. A rash may appear on the body with small red scaly bumps; this may be followed by flu-like symptoms such as fever and aching muscles. The symptoms disappear but may return at any time.

64. Syphilis Department of Neonatal Medicine Protocol Book. Royal Prince Alfred Hospital. Congenitalsyphilis Introduction. syphilis is a notifiable disease. http://www.cs.nsw.gov.au/rpa/neonatal/html/newprot/syphilis.htm

Department of Neonatal Medicine Protocol Book Royal Prince Alfred Hospital Congenital Syphilis Introduction Syphilis is a notifiable disease. Untreated maternal primary or latent syphilis results in fetal or perinatal death in 20 % of pregnancies, preterm delivery in 20% and congenital syphilis in 40 % of term deliveries. Incidence and Risk Factors There are no accurate figures for the incidence in the KGV population. We estimate the numbers of symptomatic congenital syphilis at no more than 1-2 cases /year, with perhaps five times that number of asymptomatic cases. The risk is increased Aboriginal babies, in babies whose mothers are unbooked, are itinerant or whose lifestyle places them at risk eg intravenous drug users. In developing countries congenital syphilis is still common. Recent migrants and refugees are therefore also at increased risk. Diagnosis Most commonly there will be a maternal history of positive syphilis serology on routine screening which will have resulted in maternal treatment. However in cases where the infection was acquired later in pregnancy than the routine maternal serology was performed, or in the cases where serology has not been performed, presentation may be with clinical disease in the baby with the commonest features being: Hepatosplenomegaly rash IUGR snuffles periostitis Serology Screening (non-specific) tests VDRL RPR (rapid plasma reagin) Specific tests TPPA (Treponema pallidum particle agglutination) FTA (fluorescent Treponemal absorption) which can be for IgG or IgM

65. Syphilis - What You Need To Know About Sexually Transmitted syphilis. syphilis is a serious disease that can affect your entire body. Asimple blood test can tell whether you have been exposed to syphilis. http://www.hc-sc.gc.ca/pphb-dgspsp/publicat/std-mts/std_q.html

66. Syphilis Translate this page http://www.sante.gouv.fr/htm/dossiers/syphilis/

67. Syphilis - Fmc Translate this page C'est bien connu. . BILAN BIOLOGIQUE D'UNE syphilis. L'examen à l'ultra-microscopereste de mise. Sa Navigateur . syphilis SECONDAIRE. http://www.esculape.com/fmc/syphilis.html

LA SYPHILIS Infection par le Tréponème. MST à déclaration obligatoire non nominale si la patient accepte le traitement. Recherche des sujets contacts et des autres MST Biologie Syphilis Primaire Syphilis Secondaire ... Syphilis Tertiaire Pour Information Mai 2002 Récrudescence de la syphilis (Info par Institut Fournier - Paris) qui objective également un abandon de l'utilisation des préservatifs et donc des sexualités à risque face au HIV Pour Information Mai 1997 Bill Clinton a récemment demandé pardon à quelques vieillards de race noire. Ce sont les survivants d'une expérience ( 1932 à 1972 ). Atteints de syphilis, on faisait semblant de les soigner à coup de placébo pour observer l'évolution naturelle de la maladie. Mieux vaut être blanc et en bonne santé que noir et syphilitique. C'est bien connu. BILAN BIOLOGIQUE D'UNE SYPHILIS L'examen à l'ultra-microscope reste de mise. Sa négativité n'élimine pas le diagnostic BILAN INITIAL DE DEPISTAGE VDRL : Veneral Disease Reaserch Laboratory. TPHA : Treponema Pallidum Haemagglutination Assay ( plus spécifique ).

68. THE MERCK MANUAL, Sec. 13, Ch. 164, Sexually Transmitted Diseases Genital Herpes. Genital Warts. Sexually Transmitted Enteric Infections. clickhere for navigation help. syphilis. ACQUIRED syphilis. Etiology and Pathology. http://www.merck.com/pubs/mmanual/section13/chapter164/164d.htm

69. Advanced Search April 15, 1999 AFP Resolving the Common Clinical Dilemmas of syphilis. TABLE 1Common Presentations in the Different Stages of syphilis. Stage, Presentation. http://www.aafp.org/afp/990415ap/2233.html

Advanced Search Resolving the Common Clinical Dilemmas of Syphilis NINA R. BIRNBAUM, M.D., RONALD H. GOLDSCHMIDT, M.D., and WENDY O. BUFFETT, M.D. San Francisco, California A patient information handout on syphilis, written by the authors of this article, is provided on page 2245. The diagnosis and treatment of syphilis can present difficult dilemmas. Serologic tests can be negative if they are performed at the stage when lesions are present, and the VDRL test can be negative in patients with late syphilis. Cerebrospinal fluid examination is not required in patients with primary or secondary disease and no neurologic signs or symptoms, but it may be warranted in patients with late latent syphilis or in whom the duration of infection is unknown. Patients with penicillin allergy can be treated with alternative regimens if they have primary or secondary syphilis. Penicillin is the only effective drug for neurosyphilis; oral desensitization should be accomplished before treatment of penicillin-allergic patients. Other dilemmas may be encountered in the treatment of patients who have concurrent human immunodeficiency virus infection. W ith syphilis at an all-time low in the United Statesoccurring at a rate of 3.2 cases per 100,000 population

70. Advanced Search syphilis What It Is and How It's Treated. What is syphilis? syphilis (saysiffuh-liss) is a serious infection. What are the signs of syphilis? http://www.aafp.org/afp/990415ap/990415d.html

Advanced Search Please note: This information was as current as we could make it on the date given above. But medical information is always changing, and some information given here may be out of date. For regularly updated information on a variety of health topics, please visit familydoctor.org , the AAFP patient education Web site. An article on this topic is available in this issue of AFP Syphilis: What It Is and How It's Treated What is syphilis? Syphilis (say: siff-uh-liss) is a serious infection. It's passed from one person to another during sex. It's caused by a bacteria (germ). You could get syphilis by touching the blood or sores of a person who has syphilis, especially sores on the person's mouth, penis, vagina or anus (the opening to the rectum). What are the signs of syphilis? In men, the first sign of syphilis may be a sore on the penis. In women, the first sign may be a sore around or inside the vagina. You might not even notice the sore, because syphilis sores don't hurt. The sores go away after three to six weeks. If you don't treat syphilis early, it spreads from the sore into your blood. When syphilis gets into your blood, it can cause many problems. The most common sign is a rash. The rash may show up, often on the palms of the hands or the soles of the feet, from two weeks to two months after the sore appeared. Other signs of syphilis include fever, sore throat and swollen lymph glands.

71. New York City Department Of Health & Mental Hygiene - Sexually Transmitted Disea syphilis. What is syphilis? syphilis is an STD caused by a bacteria. Who gets syphilis?Anyone having unprotected sex with an infected person can get syphilis. http://www.nyc.gov/html/doh/html/std/stds2.html

Sexually Transmitted Disease Control Program Syphilis What is Syphilis? Syphilis is an STD caused by a bacteria. Who gets Syphilis? Anyone having unprotected sex with an infected person can get syphilis. How is Syphilis spread? Syphilis is passed from person to person through direct contact with the syphilis sore, lesion, or moist rash. It can be passed through sexual contact, which includes vaginal, anal and oral sex. Kissing can pass the disease if one of the people has a sore on the lips or in the mouth. Pregnant woman can pass the disease to their babies before birth. What are the symptoms of Syphilis? The first stage of Syphilis is marked by a single sore or chancre. It is firm, round, and painless. The chancre could appear on the penis, mouth, or lips, inside or outside the vagina or anus, or on the hand. The chancre lasts 1-5 weeks and heals on its own. The second stage of Syphilis is marked when one or more rashes appear on the hands and soles of the feet, in the groin area, and all over the body. Some of the rashes look like symptoms of other diseases. The second stage symptoms can also include fever, swollen lymph glands, sore throat, patchy hair loss, muscle aches, and tiredness. The rashes lasts 2-6 weeks and clear up on their own. About 25% of untreated people will have a return of the second stage symptoms within 12 months. If Syphilis is left untreated, the symptoms will disappear but the germ will remain within the body and may seriously damage the brain, the heart and the nervous system. The results of the inside damage shows up many years later. The final result may be death.

72. Syphilis syphilis. syphilis is a sexually transmitted disease caused by a small organism calleda spirochaete. Essential Facts, For men and women diagnosed with syphilis. http://www.stdservices.on.net/std/syphilis/

Syphilis Syphilis is a sexually transmitted disease caused by a small organism called a spirochaete. It is easily treated, but can cause serious complications if not treated early. Index Essential Facts For men and women diagnosed with syphilis More Details For students and clinicians For health care workers managing patients with syphilis. Includes clinical photographs. Syphilis screening algorithm For health care workers, to assist in the interpretation of syphilis serology. Pamphlet Information pamphlet in PDF format (21 kb) Related Pages Top of Page Home Search ... About this web site Last updated: 04 February 2003 URL: http://www.stdservices.on.net/std/syphilis/default.htm Health on the Net Code of Conduct for health-related sites Sexually Transmitted Diseases Services Internal Medicine Service Royal Adelaide Hospital First Floor, 275 North Terrace Adelaide SA 5000 Australia Telephone: +61 (8) 8226 6025 Facsimile: +61 (8) 8226 6560 Email: STD.Services@dhs.sa.gov.au

73. Ketoconazole syphilis Treponema pallidum. Book, pallidum. Stages Primary syphilisChancre at 10 to 90 days after exposure; Painless Papule ulcerates http://www.fpnotebook.com/ID155.htm

Home About Links Index ... Editor's Choice Paid Advertisement (click above). Please see the privacy statement Infectious Disease Pharmacology Bacteria ... Itraconazole Ketoconazole Terbinafine Parasite Atovaquone Chloroquine ... Antibiotics in Pregnancy Ketoconazole Nizoral Book Home Page Cardiovascular Medicine Dental Dermatology Emergency Medicine Endocrinology Gastroenterology General Medicine Geriatric Medicine Gynecology Hematology and Oncology HIV Infectious Disease Jokes Laboratory Neonatology Nephrology Neurology Obstetrics Ophthalmology Orthopedics Otolaryngology Pediatrics Pharmacology Prevention Psychiatry Pulmonology Radiology Rheumatology Sports Medicine Surgery Urology Chapter Infectious Disease Index Bacteria Dermatology Emerging Examination Ophthalmology Fever Fungus Gastroenterology Helminth Immunization Laboratory General Neurology Obstetrics Parasite Pediatrics Pharmacology Prevention Prion Procedure Rheumatology Sexually Transmitted Disease Surgery Travel Medicine Vector Virus Page Pharmacology Index Bacteria Food Bacteria Aminoglycosides Gentamycin Bacteria Anaerobe Clindamycin Bacteria Anaerobe Flagyl Bacteria Cephalosporins Bacteria Cephalosporins First Bacteria Cephalosporins Second Anaerobe Bacteria Cephalosporins Second Broad Bacteria Cephalosporins Third Bacteria Cephalosporins Third Pseudomonas Bacteria Macrolide Erythromycin Bacteria Macrolide Extended Spectrum Bacteria Nitrofurantoin Bacteria Oxazolidinone Linezolid Bacteria Penicillin Reaction Bacteria Penicillins Bacteria Penicillins Aminopenicillins Bacteria Penicillins Extended Spectrum

74. Hepatitis B Vaccine syphilis Antibody syphilis Serology. syphilis False Positive. syphilisScreening. Book, Home Page. http://www.fpnotebook.com/ID76.htm

Home About Links Index ... Editor's Choice Paid Advertisement (click above). Please see the privacy statement Infectious Disease Immunization Bacteria ... Virus Hepatitis A Immunoglobulin Hepatitis B Vaccine Influenza Vaccine Lyme Disease Vaccine MMR Vaccine Inactivated Polio Vaccine ... Yellow Fever Vaccine Assorted Pages Adult Vaccination Primary Series Immunization Status Unknown Hepatitis B Vaccine Hep B Vaccine Book Home Page Cardiovascular Medicine Dental Dermatology Emergency Medicine Endocrinology Gastroenterology General Medicine Geriatric Medicine Gynecology Hematology and Oncology HIV Infectious Disease Jokes Laboratory Neonatology Nephrology Neurology Obstetrics Ophthalmology Orthopedics Otolaryngology Pediatrics Pharmacology Prevention Psychiatry Pulmonology Radiology Rheumatology Sports Medicine Surgery Urology Chapter Infectious Disease Index Bacteria Dermatology Emerging Examination Ophthalmology Fever Fungus Gastroenterology Helminth Immunization Laboratory General Neurology Obstetrics Parasite Pediatrics Pharmacology Prevention Prion Procedure Rheumatology Sexually Transmitted Disease Surgery Travel Medicine Vector Virus Page Immunization Index Approach Adults Approach Pediatrics Approach Unknown Status Bacteria Cholera Bacteria DTaP Bacteria Hib Bacteria Meningococcal Bacteria Pneumococcus Bacteria Pneumococcus Conjugate Bacteria Td Bacteria Typhoid Virus Hepatitis A Virus Hepatitis A Immunoglobulin Virus Hepatitis B Virus Influenza Virus Lyme Virus MMR Virus Polio Virus Rabies Virus Rotavirus Virus Rubella Immunoglobulin

75. Health Ency.: Disease: Syphilis syphilis See images. See also documents on syphilis; primary, syphilis;secondary, and syphilis; tertiary. Causes and Risks. syphilis http://www.accessatlanta.com/shared/health/adam/ency/article/001327.html

SEARCH: The Web Yellow Pages HOME AJC.COM Illustrated Health Encyclopedia Important notice Ency. home Disease S Syphilis See images Overview Symptoms Treatment ... Prevention Alternative names: Lues Definition: A sexually transmitted or congenital infection caused by the bacterium Treponema pallidum. See also documents on Syphilis; primary Syphilis; secondary , and Syphilis; tertiary Causes and Risks Syphilis is an infectious disease caused by the spirochete Treponema pallidum , which penetrates broken skin or mucous membranes. Transmission occurs most frequently by sexual contact. Syphilis can also be transmitted to the fetus during any stage in pregnancy. Syphilis is widespread in the United States and primarily involves sexually active adults between 20-29 years of age. Syphilis has several stages. In the primary stage, painless sores, called chancres , appear approximately 2-3 weeks after initial exposure. Some individuals with primary syphilis may not notice chancres nor have symptoms associated with them, in particular if the chancres are located in the rectum or cervix. In about 4 to 6 weeks

76. Sick Willy Gallery - Pictures And Photos Of Syphilis Alopecia patchy hair loss - early syphilis (secondary stage). Syphilitic skinlesions - early syphilis - secondary stage. Late congenital syphilis. http://www.willyworries.com/syphilis.htm

var site="s11willyw" The pictures of gonorrhoea on this site can be supplemented by additional information found if you visit our Contraception and Sexual Health Forums, where your questions will be also be answered to the best of our ability. We have the support and assistance of several medical and nursing specialists and will do our best to help you with your queries. For more information on Gonorrhoea please enter 'gonorrhoea' in the search facility of our where we have added further information on this subject - or you can just post your question which will be answered as soon as possible by our moderator and other helpers. Please mark your question 'gonorrhoea' in the subject line. Chalmydia Gonorrhoea Hepatitis Herpes ... Other Sick Willy Stuff The pictures of chlamydia on this site can be supplemented by additional information found if you visit our Contraception and Sexual Health Forums, where your questions will be also be answered to the best of our ability. We have the support and assistance of several medical and nursing specialists and will do our best to help you with your queries.

77. Syphilis History From mercury to malaria to penicillin The history of the treatment of syphilisat the Mayo Clinic, 19161955 See History of syphilis Treatment Part 2. http://www.imsdocs.com/syphilis.htm

Internal Medicine Specialists imsdocs.com Home Health News Articles Heart Forum ... About IMS Physicians Health News and Information at your fingertips From mercury to malaria to penicillin: The history of the treatment of syphilis at the Mayo Clinic, 1916-1955 by Jeffrey S. Sartin, MD and Harold O. Perry, MD Abstract "There is nothing but Syphilis," reflected Des Esseintes ... Joris Karl Huysmans A Rebours, 1884 In this time of multitudinous broad-spectrum antibiotics, it is edifying to ponder what medicine was like before their advent. A simple streptococcal sore throat often heralded fatal rheumatic fever or glomerulonephritis, and pneumococcal pneumonia was more often than not fatal. Humankind was at the mercy of its microbes. One disease towered over all others in its psychic hold on both practitioners and their patients, namely, syphilis. Pneumonia, as Osler observed, may have been "the Captain of the Ship of Death," but syphilis was our Terminator, cruelly seeking out the weak and (presumed) wicked for judgment. In the early years of this century the frustration with the inadequacies of antisyphilitic treatment gave way to a vigorous optimism that the scourge could be controlled. Ehrlich's salvarsan (an arsenical) preceded Wagner von Jauregg's malaria therapy, and by the middle of the century both were eclipsed by a new compound, penicillin. The Mayo Clinic grew into maturity in this first half century of discovery. The era was marked by the preeminence of two men who chaired the Department of Dermatology and Syphilology. John H. Stokes and Paul A. O'Leary. These men were in the vanguard of the search for a cure for syphilis, together with Joseph Earle Moore of Johns Hopkins University.

78. Hardin MD Syphilis syphilis. STDs syphilis (Other versions Google AOL); LookSmart syphilis;MEDLINEplus syphilis Diagnosis / Symptoms National Library of Medicine; http://www.lib.uiowa.edu/hardin/md/syphilis.html

79. Congenital Syphilis syphilis Printable Version Congenital syphilis is one of the most seriousand life threatening conditions in the infant. An unborn http://www.dbpeds.org/conditions/conditions.cfm?Abbrev=syphilis

80. Handbook Of Ocular Disease Management - Syphilis syphilis Patients tend to be younger, with a history of unprotected sex. Elderlypatients may manifest latestage syphilis left untreated many years before. http://www.revoptom.com/handbook/sect7f.htm

SYPHILIS SIGNS AND SYMPTOMS Syphilis is a multi-system, multi-symptom disorder that occurs primarily through sexual transmission, though the disease can be spread through blood transfusion and direct contact with an infected lesion. Patients tend to be younger, with a history of unprotected sex. Elderly patients may manifest late-stage syphilis left untreated many years before. In cases of congenital syphilis, the patient may manifest Hutchinson's triad (interstitial keratitis, deafness and malformed teeth), osteochondritis (inflammation of both bone and cartilage), chorioretinitis, hepatosplenomegaly (enlargement of the liver and spleen), and anorexia. In the primary stage of acquired syphilis, the patient develops a painless chancre at the site of inoculation, as well as regional lymphadenopathy. While primarily genital, chancres may develop on the eyelid and conjunctiva. Other ocular signs in the primary stage include conjunctivitis, blepharitis, and alopecia. In the secondary stage of acquired syphilis, the patient will develop malaise, lymphadenopathy, fever, maculopapular skin lesions on the palms and soles, joint pain, headache, and loss of appetite. Ocular signs are most common in secondary syphilis and include episcleritis, anterior uveitis, uveitic glaucoma, neuroretinitis, chorioretinitis, ischemic retinal vasculopathy, and infectious optic neuropathy.

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