1. Gunter Blobel Lab Related Links October 11, 1999 Günter blobel Wins1999 nobel Prize in Physiology or Medicine. http://www.rockefeller.edu/labheads/blobel/blobel.html

Laboratory of Cell Biology John D. Rockefeller, Jr. Professor; Investigator, HHMI Protein traffic across intracellular membranes. We study the mechanism by which proteins, ribonucleoproteins and deoxyribonucleoproteins (e.g., viruses) move across the central channel of the nuclear pore complex to enter and exit the nucleus in yeast and mammalian cells. We also study unidirectional protein translocation across the membranes of the endoplasmic reticulum in yeast cells, across the bacterial plasma membrane, and the membranes of chloroplasts and peroxisomes. Lab Web Page Lab Members E-mail Publications Related Links: HHMI: http://www.hhmi.org/science/cellbio/blobel.htm http://www.hhmi.org/news/blobel.htm New Scientist Profile: http://www.newscientist.com/keystone/speaker_18.html Nobel Prize: http://www.nobel.se/laureates/medicine-1999.html http://cnn.com/HEALTH/9910/11/nobel.medicine.03/ http://www.nigms.nih.gov/news/releases/blobel.html http://nobelprizes.com/nobel/medicine/1999a.html REALAUDIO (Jim Lehrer Hour): http://audio.pbs.org:8080/ramgen/newshour/october99/blobel_10-11.rm?altplay=blobel_10-11.rm

2. CNN - Nobel Medicine Prize Goes To Cell Biologist Guenter Blobel - October 11, 1 will of Alfred nobel • The nobel Foundation's searchable prize archive The RockefellerUniversity • Laboratory of Cell Biology gunter blobel Note Pages http://www.cnn.com/HEALTH/9910/11/nobel.medicine.03/

MAIN PAGE WORLD U.S. LOCAL ... daily almanac MULTIMEDIA: video video archive audio multimedia showcase ... more services E-MAIL: Subscribe to one of our news e-mail lists. Enter your address: document.write(' '); Or: Get a free e-mail account E-MAIL DISCUSSION: message boards chat feedback CNN WEB SITES: AsiaNow Svenska Norge Danmark ... Italian FASTER ACCESS: europe japan TIME INC. SITES: Go To ... Time.com People Money Fortune EW CNN NETWORKS: more networks transcripts SITE INFO: help contents search ad info ... jobs WEB SERVICES: health > story page Nobel medicine prize goes to cell biologist Guenter Blobel Dr. Guenter Blobel was awarded the Nobel Prize in medicine for protein research October 11, 1999 Web posted at: 11:59 a.m. EST (1559 GMT) STOCKHOLM, Sweden (CNN) The Nobel Prize for Medicine went to Dr. Guenter Blobel of The Rockefeller University in New York Monday for pioneering research on the inner workings of the cell. Blobel's discoveries have shed new light on diseases such as cystic fibrosis, and laid the foundation for bioengineered drugs such as insulin and growth hormone. The prize is worth nearly $1 million.

3. CNN - Chatpage - U.S. News Dr. gunter blobel, nobel Prize winner for Physiology/Medicine. A chat revealingdiscoveries about the cell and how they can help cure disease. http://www.cnn.com/COMMUNITY/transcripts/1999/12/blobel/

MAIN PAGE WORLD africa americas ... news quiz CNN WEB SITES: TIME INC. SITES: Go To ... Time.com People Money Fortune EW MORE SERVICES: video on demand video archive audio on demand news email services ... pointcast DISCUSSION: message boards chat feedback SITE GUIDES: help contents search FASTER ACCESS: europe japan WEB SERVICES: Dr. Gunter Blobel, Nobel Prize winner for Physiology/Medicine A chat revealing discoveries about the cell and how they can help cure disease January 18, 2000 Web posted at: 5 p.m. EDT (CNN) Dr. Gunter Blobel, who won The Nobel Prize for Medicine for pioneering research on the inner workings of the cell, joined CNN.com on Tuesday, December 21, 1999. Dr. Blobel discussed his discoveries, which have shed new light on diseases such as cystic fibrosis and laid the foundation for bioengineering drugs such as insulin and growth hormones. Dr. Blobel heads the laboratory of cell biology at Rockefeller University. He joined the chat from his laboratory in New York. CNN.com provided a typist and the following is an edited transcript of the chat. Chat Moderator: Welcome, Dr. Gunter Blobel!

4. WorldBook General Reference Encyclopedia > Life Science > Biology > Biographies 2. gunter blobel 99 nobel Prize Winner, 99. 5. Dr. gunter blobelReceives nobel Prize For Discovery of Protein Zip Codes , 33. http://www.surfablebooks.com/worldbookgeneral/Life Science/Biology/Biographies/B

WorldBook General Reference Encyclopedia Life Science Biology Biographies ... Blobel, Gunter Blobel, Gunter Search the Web with WorldBook All of Surfable Books Match: All Any Boolean Documents 1 - 10 of 127 on the subject : Blobel, Gunter Add to my e-mail alerts Blobel , Gunter - A-to-Z Science - DiscoverySchool.com Blobel , Gunter - A-to-Z Science - DiscoverySchool.com ... Blobel , Gunter (1936-...) is a German-born biologist who is conducting important research on the movement of proteins within the cells of living organisms. ... Found by: Google , Google2 http://school.discovery.com/homeworkhelp/worldbook/atozscience/b/748935.html Gunter Blobel : 99 Nobel Prize Winner Gunter Blobel : 99 Nobel Prize Winner Nobel Foundation ... Günter Blobel . for the discovery that. " proteins have intrinsic signals that govern their transport and localization in the cell". ... Found by: Google , Google2 , HotBot http://linkage.rockefeller.edu/wli/news/blobel.html Science News: Zip Code plan for proteins wins Nobel.(cell biologist Gunter Blobel wins 1999 Nobel Prize in Physiology or Located at FindArticles.com. Read about the research of cell biologist Gunter Blobel, winner of the 1999 Nobel Prize in Physiology or Medicine. Found by: HotBot http://www.findarticles.com/cf_0/m1200/16_156/57563951/p1/article.jhtml

5. Zeal.com - United States - New - Library - Sciences - Biology - Reference Shelf 6. blobel, gunter nobel Prize Goes to Cell Biologist http//www.cnn.com/HEALTH/9910/11/nobel.medicine.03/Learn about the nobel Prize winner whose http://www.zeal.com/category/preview.jhtml?cid=562475

6. BBC News | Health | Cell Discovery Wins Nobel Medicine Prize 13, 1999 Published at 1036 GMT 1136 UK Health Cell discovery wins nobel medicineprize Dr gunter blobel has won the nobel Prize for Medicine Dr Guenter http://news.bbc.co.uk/hi/english/health/newsid_471000/471388.stm

Front Page World UK UK Politics ... Help Wednesday, October 13, 1999 Published at 10:36 GMT 11:36 UK Health Cell discovery wins Nobel medicine prize Dr Gunter Blobel has won the Nobel Prize for Medicine Dr Guenter Blobel of Rockefeller University in New York has been awarded the Nobel Prize for medicine for his research on proteins that could lead to new treatments for hereditary diseases. The Swedish academy praised Dr Blobel for discovering how proteins are transported within the human cell, work that could help to unlock the secrets of diseases such as cystic fibrosis. Dr Guenter Blobel likens the signalling system to a postal service The Nobel Prize Committee said the discovery "has had an immense impact on modern cell biological research". In a statement, the committee said: "Dr Blobel's research has helped explain the molecular mechanism behind several genetic diseases. The Daily Telegraph's Science Correspondent Roger Highfield puts the work in context ... "One example is the hereditary disease primary hyperoxaluria, which causes kidney stones at an early age. Dr Gunter Blobel's work has major implications "In some forms of familial hypercholesterolemia, a very high level of cholesterol in the blood is due to deficient transport signals.

7. BBC News | The Economy | Canadian Wins Nobel Economics Prize profile nobel award, for peace, will be announced in Oslo on Friday. The other laureatesthis year have been the German author gunter Grass; Guenter blobel, a http://news.bbc.co.uk/hi/english/business/the_economy/newsid_472000/472969.stm

Front Page World UK UK Politics ... Help Thursday, October 14, 1999 Published at 07:06 GMT 08:06 UK Business: The Economy Canadian wins Nobel economics prize Mr Mundell beside a photo of himself with former US president Ronald Reagan The Canadian-born professor Robert Mundell has won the 1999 Nobel Prize for Economics. Mr Mundell's work on monetary dynamics and optimum currency areas, dating back nearly 40 years, continues to be relevant to policy-makers, most recently in discussions on setting up the single European currency. A seminal article on currency areas he wrote in 1961 has been credited as being a starting point for the theory behind the euro. Mr Mundell pictured last year in Tuscany with family The Royal Swedish Academy of Sciences said his work had inspired generations of researchers. "Mundell's contributions remain outstanding and constitute the core of teaching in international macroeconomics," it said. The winner is a professor at New York's Columbia University. It is the 31st time that the prize for economics - the youngest Nobel - has been awarded. Changing fashions for award The BBC's Chris Giles: "Mundell's ideas are used everyday on the stock market" The five other Nobel awards - for peace, literature, medicine, physics and chemistry - were set up by a foundation after the death of Swedish entrepreneur and inventor Alfred Nobel.

8. Index Of Nobel Laureates In Medicine ALPHABETICAL LISTING OF nobel PRIZE LAUREATES IN PHYSIOLOGY AND MEDICINE. Name,Year Awarded. Bloch, Konrad, 1964. blobel, gunter, 1999. Blumberg, Baruch S. 1976. http://almaz.com/nobel/medicine/alpha.html

ALPHABETICAL LISTING OF NOBEL PRIZE LAUREATES IN PHYSIOLOGY AND MEDICINE Name Year Awarded Adrian, Lord Edgar Douglas Arber, Werner Axelrod, Julius Baltimore, David ... Medicine We always welcome your feedback and comments

9. Günter Blobel Winner Of The 1999 Nobel Prize In Physiology Or Medicine gunter blobel, a nobel Prize Laureate in Physiology or Medicine,at the nobel Prize Internet Archive. GÜNTER blobel. 1999 nobel http://almaz.com/nobel/medicine/1999a.html

G B LOBEL 1999 Nobel Laureate in Physiology or Medicine for the discovery that proteins have intrinsic signals that govern their transport and localization in the cell. Background Born: May 21, 1936 Place of birth: Waltersdorf/Silesia, Germany Residence: NY, U.S.A. Affiliation: Laboratory of Cell Biology, The Rockefeller University Address: Howard Hughes Medical Institute 1230 York Avenue New York, N.Y. 10021 USA E-mail: blobel@rockvax.rockefeller.edu Book Store Books on Protein Translocation Books on the Signal Hypothesis Featured Internet Links Blobel's Laboratory at Rockefeller University Recent publications Howard Hughes Medical Institute Research Description PubMedline search results for this laureate ... Official award announcement and background Search WWW Search The Nobel Prize Internet Archive Links added by Nobel Internet Archive visitors 1999 Holtzman Memorial Lecture Rockefeller University summary of Laboratory research Howard Hughes Medical Institute King Faisal Foundation ... Winner of the 1982 Gairdner Foundation International Award (submitted by verette@gairdner.org

10. A Gunter Blobel Il Nobel Per La Medicina Translate this page Il nobel per la medicina assegnato al tedesco gunter blobel. blobeldona metà del premio ad un paese piemontese. A ricevere il dono http://www.grtv.it/1999/ottobre99/18ottobre99/nobel18.htm

Il Nobel per la medicina assegnato al tedesco Gunter Blobel Blobel dona metà del premio ad un paese piemontese A ricevere il dono, Fubine, città della moglie Laura Maioglio GRTV Blobel cominciò le sue ricerche domandandosi come una proteina appena formata potesse uscire dalla cellula ed essere pilotata verso i canali delle membrane. Il biologo tedesco immaginò che la proteina ricevesse una sorta di segnale che funzionasse da "codice postale": anni dopo scoprì che il segnale era costituito da determinate sequenze di aminoacidi che facevano parte integrante della proteina. Oggi i biologi molecolari sono a conoscenza di un gran numero di "codici postali" e, se un giorno si riuscirà a correggere quelli "sbagliati", potrebbero essere curate alcune malattie genetiche come l’iperossaluria o l’ipercolesteloremia. V.D.F./ GRTV 18 ottobre 1999 Torna alla HomePage GRTV

11. October 15, 1999, Hour One: Nobel Roundup gunter blobel 1999 nobel Laureate in Physiology or Medicine John DRockefeller, Jr. Professor Investigator, Howard Hughes Medical http://www.sciencefriday.com/pages/1999/Oct/hour1_101599.html

THIS WEEK ON SCIENCE FRIDAY... Science Friday Archives October Hour One : Nobel Roundup This week, an annual rite of fall took place. (No, not Columbus Day!) Early in the morning on Monday and Tuesday, several innocent, unassuming scientists were awoken by a telephone call from Sweden. And for a brief time after that call, those scientists enjoyed a little peace and quiet before the Nobel Prize winners were announced publicly, and a deluge of attention began. Gunter Blobel, a cell biologist at New York's Rockefeller University, was awarded the prize for Physiology or Medicine. His work focuses on working to understand cellular "trafficking" how proteins make their way through membranes surrounding the interior parts of a cell and how cells know where to deliver a protein within the cell. Blobel discovered that each protein contains a signal (often described as an "address" or a "ZIP code") that helps guide the protein across membranes - and that makes sure that proteins intended for the mitochondria doesn't get dropped off in the nucleus instead. His work is thought to have potential for helping treat diseases in which proteins don't get correctly handled by the body. We'll talk to him and find out more.

12. La Repubblica/cultura_scienze: Al Biologo Blobel In Nobel Per La Medicina Translate this page STOCCOLMA - E' stato assegnato a gunter blobel il nobel per la medicina.Sessantatrè anni, biologo molecolare e cellulare, professore http://www.repubblica.it/online/cultura_scienze/nobel99/medi/medi.html

Premiato per gli studi sulle proteine Le sue scoperte fondamentali per le malattie genetiche Al biologo Blobel in Nobel per la medicina STOCCOLMA proteine. Nato a Waltersdorf, in Germania, lo scienziato ha ricevuto il Nobel per aver scoperto che "le proteine hanno segnali intrinseci che governano il loro trasporto nella cellula". I suoi studi avranno importanti ricadute sulle malattie genetiche e le biotecnologie. Il ricercatore con i suoi studi ha spiegato tra l'altro i meccanismi che portano le proteine a dirigersi dentro o fuori le cellule, grazie a segnali molecolari che indirizzano la via giusta da seguire. Un gran numero di Cittadino americano da anni, oggi, con il suo gruppo di lavoro di biologia cellulare alla Rockfeller university, Blobel continua a studiare i meccanismi con cui le proteine passano attraverso le membrane intracellulari. (11 ottobre 1999) Nobel per la pace Nobel per l'economia ... la letteratura DALL'ARCHIVIO di Repubblica.it I Nobel 1998 IN RETE (in inglese e italiano) Columbia University California Institute of Technology ... premi Nobel

13. Glyconutrients: Nobel Prize gunter blobel is the winner of the 1999 nobel Prize for Physiology for the discoverythat proteins have intrinsic signals that govern their transport and http://www.createlight.com/nobel.html

Nobel Prize Home Scientific Validation Testimonies Join Our Biz Team! ... Contact Us Four of the last eight Nobel Prizes for medicine have dealt with the cellular communication process and its importance to our wellness. Gunter Blobel is the winner of the 1999 Nobel Prize for Physiology for the discovery that proteins have intrinsic signals that govern their transport and localization in the cell. Gunter Blobel, M.D., Ph.D. Investigator, Rockefeller University Click here for a slide presentation presented by the Nobel E-Museum on Dr. Blobel's work. Click here for a transcript of the PBS interview with Dr. Blobel. Summary A large number of proteins carrying out essential functions are constantly being made within our cells. These proteins have to be transported either out of the cell, or to the different compartments - the organelles - within the cell. How are newly made proteins transported across the membrane surrounding the organelles, and how are they directed to their correct location? These questions have been answered through the work of this year’s Nobel Laureate in Physiology or Medicine, Dr Günter Blobel, a cell and molecular biologist at the Rockefeller University in New York. Already at the beginning of the 1970s he discovered that newly synthesized proteins have an intrinsic signal that is essential for governing them to and across the membrane of the endoplasmic reticulum, one of the cell’s organelles. During the next twenty years Blobel characterized in detail the molecular mechanisms underlying these processes. He also showed that similar "address tags", or "zip codes", direct proteins to other intracellular organelles.

14. Blobel, Gunter blobel, gunter (1936). It was one of the great pleasures of my life to donate theentire sum of the nobel Prize, in memory of my sister Ruth blobel, to the http://www.cartage.org.lb/en/themes/Biographies/MainBiographies/B/Blobel/Blobel.

Blobel, Gunter 1945 was also a turning point in my life. Until then my childhood was a perfect 19th century idyll. In the cold and snow-rich Silesian winters there were hour-long rides on Sundays in horse-drawn slays to my maternal grandparent's farm to have lunch and to spend the afternoon. The house was a magnificent 18th century manor house in the nearby Altgabel with a great hall that was decorated with hunting trophies. In the summer, of course, horse-drawn landauers were used as means of transportation. The way to school was a long one. We went there on foot and as a pack, usually consisting of one or two of my seven brothers and sisters and of children from neighboring houses. The months before and after the end of World War II were chaotic and miserable. None of my relatives had enough space to accommodate our large family leaving us divided among several relatives in different villages. There was no communication and little food. On September 9, 1945, we learned of the death of my beautiful oldest sister Ruth who, at age 19, was killed in an air raid on a train she was travelling in on April 10, 1945. She was buried in a mass grave near the site of the attack in Schwandorf, Bavaria. Ruth was born when my mother was just 20. The two had a sisterly relationship. My mother grieved over Ruth's death until the end of her own life.

15. Blobel, Gunter Translate this page blobel, Günter (1936-). Médecin et biologiste américain d'origine allemande (Waltersdorf,Silésie, 1936). Il a reçu le prix nobel 1999 de physiologie pour http://www.cartage.org.lb/fr/themes/Biographies/mainbiographie/B/Blobel/Blobel.h

Blobel, Günter Médecin et biologiste américain d'origine allemande (Waltersdorf, Silésie, 1936). Il a reçu le prix Nobel 1999 de physiologie pour ses découvertes concernant les signaux internes des protéines commandant leur transport et leur localisation dans la cellule. Titulaire d'un doctorat en médecine de l'université de Tübingen, il a effectué l'essentiel de sa carrière de chercheur en biologie cellulaire et moléculaire à l'université Rockefeller (New York). Ses travaux portèrent tout d'abord sur le réticulum endoplasmique ; il montra que pour aller du cytoplasme vers cet organite où elles sont assemblées, les protéines nouvellement synthétisées sont dotées dans leur propre séquence génétique d'un signal moléculaire («peptide signal ») qui leur permet de se diriger vers la membrane plasmique du réticulum, de s'y ancrer puis de la traverser. De ces premiers travaux, découla la découverte de nombreux autres signaux spécifiques de chaque organite (mitochondries, appareil de Golgi, peroxysome, noyau, ) qui régissent le transport des protéines dans les cellules. Certaines maladies héréditaires, telle la mucoviscidose, s'expliquent par un dysfonctionnement de ce système d'adressage.

16. Bmj.com Yamey 319 (7216): 1023 The nobel Assembly commented that gunter blobel's discovery has had an immenseimpact on modern cell biological research, highlighting its current role in http://bmj.com/cgi/content/full/319/7216/1023

Home Help Search/Archive Feedback ... Respond to this article PubMed citation Related articles in PubMed Download to Citation Manager Search Medline for articles by: Yamey, G. Alert me when: New articles cite this article Collections under which this article appears: Basic sciences BMJ 1999;319:1023 ( 16 October ) News Cell biologist wins Nobel prize Gavin Yamey , BMJ The Nobel Assembly has awarded the 1999 Nobel prize in physiology or medicine to Dr Gunter Blobel, a cell and molecular biologist at the Rockefeller University in New York, for his discovery that proteins have intrinsic signals that govern their transport and localisation in the cell. Dr Blobel joined the Rockefeller's cell biology laboratory at the end of the 1960s. Building on the work of the laboratory's previous Nobel prize winner, George Palade, Dr Blobel studied how a newly made protein, destined to become transported out of the cell, is targeted at the endoplasmic reticulum, a specialised intracellular membrane system. In 1971 he formulated his "signal hypothesis," postulating that proteins secreted out of the cell

17. Nobel Prizes Relating To The Products Used In The Results Project™ nobel Prize Winner in Medicine for 1999 DR. GÜNTER blobel Dr. gunter blobelwon the nobel Prize in Medicine for 1999 what he calls protein zip codes. http://www.resultsproject.net/nobel_prizes.html

Nobel Prize Winner in Medicine for 1999 DR. GÜNTER BLOBEL Official award announcement and background An interview with Dr. Blobel after he won the award. Blobel's Laboratory at Rockefeller University Recent publications Nobel Prize Winners in Medicine for 1994 ALFRED G. GILMAN and MARTIN RODBELL Two from US share Nobel Prize in Medicine - 'G Proteins' seen as key to cell links

18. Contenido Home el Premio nobel en Medicina al Dr. gunter blobel por descubrir que las http://www.antioxidantes.com.ar/12/Art034.htm

Comentario Editorial Premio Nobel en Medicina 1999 El Premio Nobel 1999 en Medicina le fue otorgado al Dr. Guenter Blobel, de origen alemán emigrado a los Estados Unidos y que se desempeña en el área de biología celular y molecular en la Rockefeller University de la ciudad de Nueva York. El Dr. Gunter Blobel en su laboratorio. El escueto mensaje del Karolinska Institutet del 11 de Octubre de 1999 decía que: "La Asamblea había decidido otorgarle el Premio Nobel en Medicina al Dr. Gunter Blobel por descubrir que las proteínas poseen señales intrínsecas que gobiernan su transporte y localización en la célula." Lo que parece una simple frase contiene la esencia del mecanismo por el cual funciona una célula. Desde 1970, el Dr. Blobel viene investigando un proceso que siempre intrigó a los científicos en esta área de la ciencia: como hacen las proteínas de las células para encontrar su correcta ubicación en las organelas celulares luego de atravesar sus membranas. Desde 1967, el Dr. Blobel comenzó a trabajar en el servicio a cargo del Dr. George E. Palade, un pionero en biología celular. Sus investigaciones fueron una continuación del camino iniciado por Palade.

19. BestCalls blobel, gunter J. BLOCK, STEPHEN A. BLOCK, STEPHEN C. BLOCK, STEVE; BLUESTEIN, DG; PRICE,ROWE; PRIZEWINNING, DOUGLAS J. WETMORE nobel; REID, HG; REID, HERBERT G http://www.edgar-online.com/brand/bestcalls/people/companypeople.asp?cik=51253

20. Nobel Week 1999 nobel Assembly at the Karolinska Institute (waiting for press conference); nobelAssembly at the Karolinska Institute (pressconference with gunter blobel); http://www.geocities.com/dimsla_ru/siyss.htm

Nobel Week 1999 Home About/CV Photogallery Science Publications Pineal Gland Collaboration Software Hobby 3D-graphics Games Other Links e-mail Here are some photos from 24th SIYSS (Stockholm International Youth Science Seminar) The history behind SIYSS goes as far back as 1976. The Federation of Young Scientists (in Swedish "Förbundet Unga Forskare", organized its forst SIYSS program with inspiration from the United States Science Service and with help from the Nobel Foundation. In 1999 there were 30 participants from 17 different countries. The students are introduced to Swedish science and research ant to Swedish culture and history. The participants in SIYSS are selected in different ways. Some ofthem are winners of the National Science Fairs which are held in many of the participating countries, others are selected as the best students of their universities or representatives of organizations corresponding to the Swedish Federation of Young Scientists. All 30 participants of 24th SIYSS after the Nobel Banquet Stident's Hotel "AF Chapman"

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