81. Zeal.com - United States - New - Library - Society - News & Magazines - In The N nobel Prize Winners Preview Category, http://www.zeal.com/category/preview.jhtml?cid=562458

82. Günter Blobel HHMI INVESTIGATORS / Günter blobel. Intracellular Protein Traffic, Günterblobel, MD, Ph.D. Investigator, The Rockefeller University Biography http://www.hhmi.org/research/investigators/blobel.html

HHMI INVESTIGATORS INTERNATIONAL RESEARCH SCHOLARS HHMI-NIH RESEARCH SCHOLARS LAB SAFETY ... HHMI HOME ALSO OF INTEREST Search PubMed The Blobel Lab 1999 Nobel Prize Intracellular Protein Traffic Investigator, The Rockefeller University Biography... Summary: Membranes are impermeable to proteins. Essentially, proteins are synthesized in only one of the cellular compartments, the cytoplasm (although a few are synthesized in the mitoplasm of mitochondria and the chloroplasm of chloroplasts). How are newly synthesized proteins directed to their proper membranes and compartments? And how do these relatively large molecules traverse the compartmental membranes without destroying the essential gradients of small molecules and ions that exist across each of these membranes? How are membrane proteins integrated into membranes such that each member of a given species of membrane protein exhibits precisely the same domains on the cis side and the trans side of the membrane? Of particular interest is that PCCs are also used for the integration of membrane proteins into the lipid bilayer. Accordingly, the PCC is predicted to reversibly open in two dimensions, with opening across the membrane triggered by the signal sequence, and opening to the lipid bilayer triggered by the "stop-transfer" sequence of the translocating membrane protein. Hence the PCC, which is able to respond to sequence information in the translocating chain, is more than merely a passive conduit.

83. UW Doctoral Recipiant Wins Nobel Prize A university professor who was advisor to nobel Prize winning cell biologist GunterBlobel while he studied oncology here says he's not surprised the onetime http://www.biotech.wisc.edu/Education/biotechnews/BlobelNobel.html

UW DOCTORIAL RECIPIANT WINS NOBEL PRIZE A university professor who was advisor to Nobel Prize winning cell biologist Gunter Blobel while he studied oncology here says he's not surprised the one-time doctoral candidate has received the international honor. "This has been building for the last 10 years at least," says professor Van R. Potter of the McArdle Lab for Cancer Research . "His name has come up before. It's not a surprise at all." Blobel received a doctoral degree in oncology in 1967 from UW -Madison, where he worked with Potter in the McArdle Lab. Blobel was in Madison from 1962-1967. "I remark with a wink that he's the first of my students to get a Nobel prize, but there are several out there who deserve it," Potter says. "There have been some very outstanding people who have gone through here, and we're proud of Blobel because he came from here." While in Madison, Blobel's research interest was in methods for separating cells into their different components. He eventually came to study what he called "protein traffic," how proteins migrate from one part of the cell to another carrying specific messages. In particular, he had an interest in the protein-mediated exchange of information between the cell's nucleus and cytoplasm. "There is protein traffic in the body," Potter explains, citing the pituitary gland's ability to secrete regulatory proteins. "But he studied protein traffic inside the cell."

84. Science News: Zip Code Plan For Proteins Wins Nobel.(cell Biologist Gunter Blobe Page 1 2 Next. Zip Code plan for proteins wins nobel.(cell biologist GunterBlobel wins 1999 nobel Prize in Physiology or Medicine)(Brief Article) http://www.findarticles.com/cf_dls/m1200/16_156/57563951/p1/article.jhtml

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85. 1999Äêŵ±´¶ûÉúÀíѧ The summary for this Chinese (Simplified) page contains characters that cannot be correctly displayed in this language/character set. http://life.ac.cn/xyls/nobel-med99c.htm

1999Äê10ÔÂ11ÈÕ£¬Åµ±´¶ûίԱ»áÐû²¼À¹úŦԼÂå¿Ë·ÆÀÕ´óѧµÄGunter Blobel»ñµ1999Äêŵ±´¶ûÉúÀíѧ/ҽѧ½±¡£ËûµÄ¹±Ï×ÊÇ·¢ÏÖµ°°×ÖʾßÓпØÖÆÆäÔËÊäºÍ¶¨Î»µÄÄÚÔÚÐźš£ Gunter Blobel Gunter Blobel Gunter Blobel Gunter Blobel DNA Gunter Blobel George Palade George Palade Albert Claude Christian de Duve Gunter Blobel Gunter Blobel Gunter Blobel DNA RNA ÕÅÓÑÉиù¾ÝOfficial award announcement±àд

86. ?-? The summary for this Chinese (Simplified) page contains characters that cannot be correctly displayed in this language/character set. http://www.newlifebp.org.cn/shidian/zhuanti/nobel/news.htm

87. ? NOBEL G 1999 ?a The summary for this Greek page contains characters that cannot be correctly displayed in this language/character set. http://www.sciam.gr/02-00/nobel.html

ÔÁ ÂÑÁÂÅÉÁ NOBEL ÉÁ ÔÏ 1999 GERARDUS 'T HOOFT ÐáíåðéóôÞìéï ôïõ Ultrecht, Ïëëáíäßá MARTINUS J. G. VELTMAN ÐáíåðéóôÞìéï ôïõ Michigan (åðßôéìïò) Åí ôïýôïéò, ï Martinus J. Veltman åðé÷åßñçóå ìßá óõíïðôéêÞ áíÜëõóç ôùí ìáèçìáôéêþí äõóêïëéþí êáé áíÝðôõîå Ýíá õðïëïãéóôéêü ðñüãñáììá ãéá ôçí åðéôÝëåóç ôçò Üëãåâñáò. Ï Gerardus 't Hooft ðñïó÷þñçóå óôï ó÷Ýäéï ùò ìåôáðôõ÷éáêüò öïéôçôÞò ôï 1969. ÌÝ÷ñé ôïí Éïýëéï ôïõ 1971, ï 't Hooft åß÷å åðéôý÷åé íá äåßîåé üôé ìßá óõãêåêñéìÝíç çëåêôñáóèåíÞò èåùñßá èá ìðïñïýóå ðñÜãìáôé íá åðáíáêáíïíéêïðïéçèåß ëüãù ôùí âáóéêþí ÷áñáêôçñéóôéêþí ôçò: ôá óùìÜôéá ôçò áóèåíïýò áëëçëåðßäñáóçò áðïêôïýóáí ôç ìÜæá ôïõò ìÝóù ìßáò äéáäéêáóßáò ðïõ ïíïìÜæåôáé áõèüñìçôï óðÜóéìï óõììåôñßáò, ðïõ ðåñéëáìâÜíåé íÝá âáèìùôÜ óùìÜôéá (âëÝðå åéêüíá êÜôù). Ïé Veltman êáé 't Hooft åéóÞãáãáí åðßóçò ìßá íÝá ôå÷íéêÞ ãéá ôïí ÷åéñéóìü ôùí áðåéñéóìþí ôÝôïéùí èåùñéþí. ÁõôÞ ç ìÝèïäïò äéáóôáôéêÞò ïìáëïðïßçóçò, ç ïðïßá ðåñéëáìâÜíåé ôçí ðñïóùñéíÞ ôñïðïðïßçóç ôïõ áñéèìïý ôùí äéáóôÜóåùí ôïõ ÷þñïõ óôïõò õðïëïãéóìïýò, Þôáí áíåêôßìçôç óôçí ïëïêëÞñùóç ïñéóìÝíùí ëåðôïìåñåéþí ôçò áðüäåéîçò ôçò åðáíáêáíïíéêïðïßçóçò êáé ÷ñçóéìïðïéÞèçêå åõñýôáôá. Ôï áðïôÝëåóìá åíèÜññõíå ôïõò èåùñçôéêïýò êáé ôïõò ðåéñáìáôéêïýò íá åðéêåíôñùèïýí óôçí åðáíáêáíïíéêïðïéÞóéìç çëåêôñáóèåíÞ èåùñßá, ç ïðïßá áðü ôüôå Ý÷åé ãßíåé Ýíá áðü ôá âáóéêÜ êïììÜôéá ôïõ ÊáèéåñùìÝíïõ Ðñïôýðïõ. Ïé ôå÷íéêÝò ðïõ îåêßíçóáí ïé 't Hooft êáé Veltman åðÝôñåøáí ëåðôïìåñåßò ðñïâëÝøåéò ôùí éäéïôÞôùí ôùí W êáé Z óùìáôéäßùí, åíþ êÜðïéåò ðñïóåããéóôéêÝò ðñïâëÝøåéò ó÷åôéêÜ ìå ôï êïñõöáßï quark Ý÷ïõí åðéâåâáéùèåß áðü ôá ðåéñÜìáôá.

88. Food-growntypeCoQ10 Click here to read it. For instance, it will include the words of Dr. GunterBlobel, the 1999 nobel Prize winner in Physiology or Medicine. http://www.medibolics.com/FoodgrowntypeCoQ10.htm

HIV Nutrient Supplementation: Should I Use "Food-Grown-Type" Co-Q10? By Michael Mooney, December, 2002 Question: I have read your How To Manage Side Effects Guide recommendations and heard the words of Charlie Smigelski, a dietitian who specializes in HIV nutrition and works at Tufts and Harvard University. You both said that Co-Q10 is an immune-supporting nutrient, and that it might help to reduce some HIV-related lipodystrophy symptoms, like fat loss in the face. Facial fat loss is causing me to be terribly depressed. I went to a health food store to ask about Co-Q10 and they told me that I should only take "food-grown-type" Co-Q10 because regular Co-Q10 can be “toxic” to my immune system. They also said that "food-grown-type" Co-Q10 " has 9.6 times more anti-oxidant activity than regular USP-type CoQ10.” I haven’t heard you say anything about "food-grown" nutrients, so I was curious why you haven’t written about them. Should I buy "food-grown-type" Co-Q10 instead of regular CoQ10? It costs a lot more. Definition of terms: USP stands for United States Pharmacopoeia, a standard for measuring production purity in isolated nutrients, like vitamins, minerals and anti-oxidants. USP-type Coenzyme-Q10 is what is commonly sold in health stores. It is the type of Co-Q10 that has been investigated in numerous independent scientific studies over many years. USP-type Co-Q10 has been proven to provide several benefits in published studies in the peer-reviewed medical literature. Co-Q10 is especially noted for its potential benefits to the cardiovascular system. (See: Frishman WH. Co-enzyme Q10: a new drug for cardiovascular disease. J Clin Pharmacol 1990 Jul;30(7):598-608.)

89. OUP USA: Life Evolving It is the testament of one of the great biologistphilosophers of our time. GunterBlobel, nobel Laureate in Physiology and Medicine An original thinker and http://www.oup-usa.org/isbn/0195156056.html

Life Sciences or Browse by Subject In Stock Standard Sample Chapter Life Evolving Molecules, Mind, and Meaning CHRISTIAN DE DUVE A master class in the nature of life, taught by one of the world's most eminent scientists, Nobel laureate Christian de Duve In just a half century, humanity has made an astounding leap in its understanding of life. Now, one of the giants of biological science, Christian de Duve, discusses what we've learned in this half century, ranging from the tiniest cells to the future of our species and of life itself. In Life Evolving , one of our most eminent scientists sums up what he has learned about the nature of life and our place in the universe. An extraordinarily wise and humane volume, it will fascinate readers curious about the world around them and about the impact of science on philosophy and religion. "A well-written, engaging scientific tour de force.... de Duve exhibits an extraordinary skill in conveying his deep knowledge of biology.... Both a first-rate scholar and an accomplished popularizer of science...de Duve moves with equal familiarity and eloquence from scientific papers to French poets.... Life Evolving forces the reader to avoid intellectual complacency and to articulate one's own arguments to effectively address his position. These are, in themselves, major reasons to appreciate the book."

90. ¦^¨ì The summary for this Chinese (Traditional) page contains characters that cannot be correctly displayed in this language/character set. http://www.tainandoctor.com/works_04.htm

¦^¨ì" ¬KÀM¤§¤Í§@«~ " 1999¦~¿Õ¨©º¸¥Í²z¡BÂå¾Ç¼ú ¡]The 1999 Nobel Prize in Physiology or Medicine¡^ ¬KÀM¶E©ÒÅU°Ý ¬hÄRªâ¦Ñ®v ¾ã²z «e¨¥¡G 1999¦~¿Õ¨©º¸¥Í²z¡BÂå¾Ç¼ú ¦ý¬O¡A³J¥Õ½è¦p¦ó¬ï¹L³o¨Ç¬]Äæ¡H ³J¥Õ½è¬O¤j¤À¤l¡A¥¦¤S¦p¦ó¯à¾î¶V¥Ñ¯×½èºò±K¾a¦b¤@°_¦Ó§Î¦¨ªº½¤¡]³ò¦í­M¾¹¡^©O¡H´X¤Q¦~¥H«e¡A¨¤£²M·¡¦p¦ó§â­è»s³yªº³J¥Õ½è«ü¤Þ¦Ü¥¿½Tªº¦ì¸m¡A©Ò¥H¡ABlobelªº°^Äm¬O¸Ñ¨M¤F³o¨ÇøD¡C ¦^¨ì³Ì¤W­±

91. Áñ÷åßá ÅëëçíéêÞò ÉáôñéêÞò The summary for this Greek page contains characters that cannot be correctly displayed in this language/character set. http://www.mednet.gr/archives/1999-4/414.html

28-Jul-2000 ÂÑÁÂÅÉÏ NOBEL ÖÕÓÉÏËÏÉÁÓ/ÉÁÔÑÉÊÇÓ 1999 Gunter Blobel Howard Hughes Medical Institute, The Rockefeller University, New York, USA in vitro áíáðáñáãùãÞò ôïõ öáéíïìÝíïõ ôçò ìåôáöïñÜò ôùí ðñùôåúíþí. ¸ôóé, èá êáôáóôåß äõíáôÞ ç äçìéïõñãßá ðñùôåúíþí-öáñìÜêùí ðïõ èá êáôåõèýíïíôáé ðñïò óõãêåêñéìÝíá êõôôáñéêÜ äéáìåñßóìáôá ðïõ ðÜó÷ïõí Þ, ãåíéêüôåñá, ç ðáñáãùãÞ èåñáðåõôéêþí ðñùôåúíéêþí ðáñáãüíôùí ìå ôç ÷ñÞóç ðïëýðëïêùí êõôôáñéêþí ìïíôÝëùí (protein factories). ÁõôÞ ôç óôéãìÞ, ïé Ýñåõíåò ôïõ Blobel åóôéÜæïíôáé óôç äéåñåýíçóç ôçò ìåôáêßíçóçò ìåãÜëùí ðñùôåúíþí, üðùò åêåßíåò ðïõ óõíäÝïíôáé ìå ôï RNA êáé ôï DNA, ðñïò ôïí ðõñÞíá. www.nobel.se/laureates/medicine-1999.html

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