1. Michael S. Brown Winner Of The 1985 Nobel Prize In Medicine michael S. brown, a nobel Prize Laureate in Physiology and Medicine, at the nobelPrize Internet Archive. michael S. brown. 1985 nobel Laureate in Medicine http://almaz.com/nobel/medicine/1985a.html

M ICHAEL S B ROWN 1985 Nobel Laureate in Medicine for their discoveries concerning the regulation of cholesterol metabolism. Background Born: 1941 Residence: U.S.A. Affiliation: University of Texas Health Science Center at Dallas, Dallas, TX Featured Internet Links Prize co-recipient: Joseph L. Goldstein Search WWW Search The Nobel Prize Internet Archive Nobel News Links 2 Texas Doctors Celebrate Nobel Medicine Prize at MIT Links added by Nobel Internet Archive visitors Winner of The Gairdner Foundation Int'l Award Michael S. Brown – Biography (submitted by Chinnappan Baskar Back to The Nobel Prize Internet Archive Literature Peace ... Medicine We always welcome your feedback and comments

2. Index Of Nobel Laureates In Medicine ALPHABETICAL LISTING OF nobel PRIZE LAUREATES IN PHYSIOLOGY AND MEDICINE. Name,Year Awarded. Bovet, Daniel, 1957. Brenner, Sydney, 2002. brown, michael S. 1985. http://almaz.com/nobel/medicine/alpha.html

ALPHABETICAL LISTING OF NOBEL PRIZE LAUREATES IN PHYSIOLOGY AND MEDICINE Name Year Awarded Adrian, Lord Edgar Douglas Arber, Werner Axelrod, Julius Baltimore, David ... Medicine We always welcome your feedback and comments

3. Michael S. Brown - Biography michael S. brown was born on April 13, 1941, in Brooklyn, New York brown and his wife,Alice, have two daughters Elizabeth (born in 1973 From Les Prix nobel 1985 http://www.nobel.se/medicine/laureates/1985/brown-bio.html

Michael S. Brown was born on April 13, 1941, in Brooklyn, New York, the eldest child of Harvey Brown, a textile salesman, and Evelyn Brown, a housewife. His sister Susan was born three years later. When Brown was 11 years old the family moved to Elkins Park, Pennsylvania, a suburb of Philadelphia, where Brown attended Cheltenham High School. An amateur radio operating license obtained at age 13 led to a life-long fascination with science. A serious interest in journalism also developed early. These two passions, science and writing, have remained paramount ever since. Brown graduated in 1962 from the College of Arts and Sciences of the University of Pennsylvania, with chemistry as his major subject. He spent most of his time at the headquarters of the student newspaper, the Daily Pennsylvanian, where he served as features editor and briefly as editor-in-chief. In 1966 Brown received his M.D. degree from the University of Pennsylvania School of Medicine. In 1964 he married Alice Lapin, a companion from childhood. The next two years were spent as intern and resident in Internal Medicine at the Massachusetts General Hospital in Boston. Here Brown met

4. Medicine 1985 The nobel Prize in Physiology or Medicine 1985. for their discoveries concerningthe regulation of cholesterol metabolism . michael S. brown, Joseph L. Goldstein. http://www.nobel.se/medicine/laureates/1985/

The Nobel Prize in Physiology or Medicine 1985 "for their discoveries concerning the regulation of cholesterol metabolism" Michael S. Brown Joseph L. Goldstein 1/2 of the prize 1/2 of the prize USA USA University of Texas Health Science Center at Dallas Dallas, TX, USA University of Texas Health Science Center at Dallas Dallas, TX, USA b. 1941 b. 1940 The Nobel Prize in Physiology or Medicine 1985 Press Release Presentation Speech Michael S. Brown ... Banquet Speech The 1985 Prize in: Physics Chemistry Physiology or Medicine Literature ... Economic Sciences Find a Laureate: Last modified June 16, 2000 The Official Web Site of The Nobel Foundation

5. Brown, Michael S. brown, michael S.,. in full michael STUART brown (b. April 13, 1941, New York, NY,US), American molecular geneticist who, along with Joseph L. Goldstein http://www.britannica.com/nobel/micro/88_67.html

Brown, Michael S., in full MICHAEL STUART BROWN (b. April 13, 1941, New York, N.Y., U.S.), American molecular geneticist who, along with Joseph L. Goldstein , was awarded the 1985 Nobel Prize for Physiology or Medicine for their elucidation of a key link in the metabolism of cholesterol in the human body. Brown graduated from the University of Pennsylvania, Philadelphia, in 1962 and received his M.D. from that university's medical school in 1966. He became friends with Goldstein when they were both working as interns at Massachusetts General Hospital in Boston during 1966-68. After conducting research at the National Institutes of Health from 1968 to 1971, he became an assistant professor at the Southwestern Medical School in Dallas, Texas, where he was reunited with his colleague Goldstein. In Dallas the two men began their collaborative research on the genetic factors that are responsible for high levels of cholesterol in the bloodstream. They compared the cells of normal persons with those of persons having familial hypercholesterolemia, which is an inherited tendency to get abnormally high blood cholesterol levels and, as a result, atherosclerosis and other circulatory ailments. Brown and Goldstein were able to trace a genetic defect in the afflicted persons that resulted in their lacking or being deficient in cell receptors for low-density lipoproteins (LDL), which are the primary cholesterol carrying particles. Their research established that these cell receptors draw the LDL particles into the cells as a prelude to breaking them down, and thus remove them from the bloodstream. The two men also discovered that the cell capture of such lipoproteins inhibits the further production of new LDL receptors by the cells, thus explaining how high-cholesterol diets overwhelm the body's natural capacity for withdrawing cholesterol from the bloodstream.

6. Nobel Prize Winners A-C substances, brown, michael S. 1985, physiology/medicine, US, discoveryof cell receptors relating to cholesterol metabolism, Buchanan http://www.britannica.com/nobel/win_a-c.html

Article Year Category Country* Achievement Literary Area Addams, Jane peace U.S. Adrian (of Cambridge), Edgar Douglas Adrian, 1st Baron physiology/medicine U.K. discoveries regarding function of neurons Agnon, S.Y. literature Israel novelist Alder, Kurt chemistry West Germany discovery and development of diene synthesis Aleixandre, Vicente literature Spain poet physics Sweden work in magnetohydrodynamics and in antiferromagnetism and ferrimagnetism Allais, Maurice economics France contributions to the theory of markets and efficient use of resources Altman, Sidney chemistry U.S. discovery of certain basic properties of RNA Alvarez, Luis W. physics U.S. work with elementary particles, discovery of resonance states American Friends Service Committee peace U.S. Amnesty International peace (founded 1961) Anderson, Carl David physics U.S. discovery of the positron Anderson, Philip W. physics U.S. contributions to understanding the behaviour of electrons in magnetic, noncrystalline solids Andric, Ivo literature Yugoslavia novelist Anfinsen, Christian B.

7. UT Southwestern Nobel Laureates: Dr. Michael Brown Publications. The 1985 nobel Prize in Medicine michael S. Brownand Joseph L. Goldstein (Garfield critique of citation impact). http://www3.utsouthwestern.edu/library/speccol/archives/nobel/brown.htm

Michael Brown, M.D. Professor of Molecular Genetics and Internal Medicine Director, the Erik Jonsson Center for Research in Molecular Genetics and Human Disease Dr. Brown received the 1985 Nobel Prize in Physiology or Medicine for discoveries concerning the regulation of cholesterol metabolism. "'From discovery to understanding the logic of a system one studies...is a very long way; this makes the difference between everyday science and great science — science that outlives for centuries, if not forever, the men and women who dug it out of the darkness of the unknown.' Dr. George E. Palade, Nobel laureate, at a dinner for Goldstein and Brown Pamela Lyon, "The Great Adventure," Biologue 1986 pgs. 10-11, 25. "The Great Adventure" (from Southwestern Medicine PDF version "Trail of Discovery" (from Southwestern Medicine PDF version Research Interests Nobel Prize Press Release Biography (from the Nobel site) Community of Science Profile and List of Recent Publications "The 1985 Nobel Prize in Medicine Michael S. Brown and Joseph L. Goldstein..."

8. UT Southwestern Nobel Laureates: Dr. Joseph L. Goldstein Publications. The 1985 nobel Prize in Medicine michael S. brown andJoseph L. Goldstein (Garfield critique of citation impact). http://www3.utsouthwestern.edu/library/speccol/archives/nobel/goldstein.htm

Joseph L. Goldstein, M.D. Professor of Molecular Genetics and Internal Medicine, Regental Professor, Chairman, Department of Molecular Genetics Dr. Goldstein received the 1985 Nobel Prize in Physiology or Medicine for discoveries concerning the regulation of cholesterol metabolism. "...scientists and academicians now are using the word 'paradigm' to describe the Nobel Prize-winning work of Drs. Michael S. Brown and Joseph L. Goldstein...." Bob Fenley, "Trail of Discovery," Biologue 1986 pgs. 16-18. "The Great Adventure" (from Southwestern Medicine PDF version "Trail of Discovery" (from Southwestern Medicine PDF version Research Interests Nobel Prize Press Release Biography (from the Nobel site) Community of Science Profile and List of Recent Publications "The 1985 Nobel Prize in Medicine - Michael S. Brown and Joseph L. Goldstein..." (Garfield critique of citation impact) Maintained by: Archives Updated: 4/24/2002 Nobel Home Archives Home Special Collections Library Home

9. C.H.S. Hall Of Fame - Michael S. Brown Class of 1958 Inducted in 1987. michael S. brown 1985 nobel Prize inMedicine Winner of the 1985 nobel Prize in Medicine for discoveries http://www.cheltenhamalumni.org/halloffame/biographies/brown.htm

previous back to index next Class of 1958 Inducted in 1987 Michael S. Brown 1985 Nobel Prize in Medicine Winner of the 1985 Nobel Prize in Medicine for discoveries about cholesterol that could help prevent heart attacks and strokes, Dr. Brown is a molecular geneticist at the University of Texas Health Center in Dallas. A life-long fascination with science began with an amateur radio operating license obtained at the age of 13, while a student at Thomas Williams Junior High School in Wyncote. At T.W. and then at Cheltenham High, this interest in science was fostered along with a growing interest in writing Dr. Brown's two major areas of interest. Dr. Brown graduated from the University of Pennsylvania undergraduate school and School of Medicine. He was elected to Phi Beta Kappa. He spent several years at the National Institutes of Health, first as a Clinical Associate in Gastroenterology and Hereditary Diseases and then in the Laboratory of Biochemistry, where he learned the techniques of enzymology and the fundamental principles of metabolic regulation. In 1971 Dr. Brown joined the Division of Gastroenterology in the Department of Internal Medicine at the University of Texas Southwestern Medical School in Dallas. Here his research work continued with his friend and associate, Dr. Joseph L. Goldstein. In 1974 Brown was promoted to Associate Professor and to Professor in 1976. In 1977 he was appointed Paul J. Thomas Professor of Medicine and Genetics and Director of the Center for Genetic Diseases. In 1985 Dr. Brown was named Regental Professor of the University of Texas.

10. ALPHABETICAL LISTING OF NOBEL PRIZE LAUREATES IN PHYSIOLOGY AND MEDICINE FRONTIERS IN BIOSCIENCE; ALPHABETICAL LISTING OF nobel PRIZE LAUREATES IN PHYSIOLOGYAND MEDICINE, Name, Year Awarded. Bovet, Daniel, 1957. brown, michael S. 1985. http://www.bioscience.org/urllists/nobelm.htm

FRONTIERS IN BIOSCIENCE; ALPHABETICAL LISTING OF NOBEL PRIZE LAUREATES IN PHYSIOLOGY AND MEDICINE Name Year Awarded Adrian, Lord Edgar Douglas Arber, Werner Axelrod, Julius Baltimore, David ... Zinkernagel, Rolf M.

11. ALPHABETICAL LISTING OF NOBEL PRIZE LAUREATES IN CHEMISTRY Zsigmondy, Richard Adolf, 1925. ALPHABETICAL LISTING OF nobel PRIZE LAUREATESIN PHYSIOLOGY AND MEDICINE. Bovet, Daniel, 1957. brown, michael S. 1985. http://www.bioscience.org/urllists/nobelc.htm

FRONTIERS IN BIOSCIENCE; ALPHABETICAL LISTING OF NOBEL PRIZE LAUREATES IN CHEMISTRY, PHYSIOLOGY AND MEDICINE ALPHABETICAL LISTING OF NOBEL PRIZE LAUREATES IN CHEMISTRY Name Year Awarded Alder, Kurt Altman, Sidney Anfinsen, Christian B. Arrhenius, Svante August ... Zsigmondy, Richard Adolf ALPHABETICAL LISTING OF NOBEL PRIZE LAUREATES IN PHYSIOLOGY AND MEDICINE Name Year Awarded Adrian, Lord Edgar Douglas Arber, Werner Axelrod, Julius Baltimore, David ... Zinkernagel, Rolf M. Source: The Nobel Prize Internet Archive

12. MBL :: Inside The MBL :: News :: Press Releases July 24, 2002 nobel Laureate to Speak on Genetic Defenses Against Heart Attacks WOODS HOLE, MA— michael S. brown, recipient of the 1985 nobel Prize in http://www.mbl.edu/inside/what/news/press_releases/2002_pr_7_24_02.html

What is the MBL? News Education Research Services ... Strategic Planning Visit Tours Visitors Center Gift Shop Directions Join MBL Associates Corporation Membership Employment Home ... Press Releases July 24, 2002 Nobel Laureate to Speak on "Genetic Defenses Against Heart Attacks" The average American maintains a blood cholesterol level that is above the 90th percentile for the human species considered as a whole. This accounts for the 10-fold higher rate of heart attacks in the U.S. as compared with countries where the diet is low in fat and cholesterol. In his lecture titled, "Genetic Defenses Against Heart Attacks," Dr. Brown will discuss how the body controls the level of cholesterol in blood, why some people are more sensitive to high fat diets than others, and why these control mechanisms don't protect us from high fat diets. Michael S. Brown David L. Garbers The Marine Biological Laboratory is an independent scientific institution, founded in 1888, that undertakes the highest level of creative research and education in biology, including the biomedical and environmental sciences. HOME EDUCATION RESEARCH INSIDE THE MBL ... web@mbl.edu

13. 1/29/2002, Chemistry's Nobel Laureates - Almanac, Vol. 48, No. 20 michael S. brown 1985 nobel PRIZE IN MEDICINE BS in Chemistry (1962), MD(1966), University of Pennsylvania. Born in Brooklyn, New York in 1941. http://www.upenn.edu/almanac/v48/n20/NobelBios.html

Chemistry's Nobel Laureates Anifsen Brown Prusiner Zewail ... Shirakawa CHRISTIAN B. ANFINSEN 1972 NOBEL PRIZE IN CHEMISTRY M.S. in Chemistry (1939), University of Pennsylvania, Born in Monessen, Pennsylvania in 1916. B.S., Swarthmore College, Ph.D., Harvard Medical School. His award acknowledges pioneering work in establishing the connection between chemical structure and catalytic activity of the active center of ribonuclease. His work provided an answer to the question concerning the way in which the active enzyme is formed in living cells. Christian B. Anfinsen died in 1995. Anifsen Brown Prusiner Zewail ... Shirakawa MICHAEL S. BROWN 1985 NOBEL PRIZE IN MEDICINE B.S. in Chemistry (1962), M.D. (1966), University of Pennsylvania Born in Brooklyn, New York in 1941. He was awarded for discoveries concerning "the regulation of cholesterol metabolism." These discoveries have led to new approaches to the treatment and prevention of atherosclerosis. While at Penn, Michael Brown also served as features editor and editor-in-chief of the Daily Pennsylvanian. He is currently a Professor of Molecular Genetics and Internal Medicine & Director of the Erik Jonsson Center for Research in Molecular Genetics and Human Disease at the University of Texas Southwestern Medical Center.

14. Gazette: Gazetteer (Mar/Apr 2002) Hon’97, the 1999 nobel Laureate in chemistry; Dr. Stanley Prusiner C’64 M’68Hon’98, the 1997 nobel Laureate in medicine; Dr. michael S. brown C’62 M http://www.upenn.edu/gazette/0302/0302gaz3.html

Previous Gazetteer item Next Gazetteer item Mar/Apr Contents Gazette home HONORS Photo by Jim Graham Dr. Alan Previous Gazetteer item Next Gazetteer item Mar/Apr Contents Gazette home ... The Pennsylvania Gazette Last modified 2/28/02

15. Nobel Laureates - 7. Lectures And Nobel Laureates - NIH 1998 Almanac Content nobel Laureates. Laureate, DRR. michael S. brown, USA (shared with JL Goldstein,USA), Physiology or medicine, 1985, NHLBI, NIGMS, DRR. Joseph http://www.nih.gov/about/almanac/1998/lectures/nobel.html

NIH 1998 Almanac Lectures and Nobel Laureates Nobel Laureates Laureate Field Year Supporting Institute(s) Paul D. Boyer, U.S.A. (shared with J.C. Skou) Chemistry NIGMS, NIDDK Jens C. Skou, Denmark (shared with P.D. Boyer) ......do NINDS Stanley B. Prusiner, U.S.A. Phyisology or medicine NINDS, NIA, NCRR, NIGMS Edward B. Lewis, U.S.A. (shared with C. Nusslein-Volhard, Germany, and E.F. Wieschaus, U.S.A.) Physiology or medicine NICHD, NIGMS Eric F. Wieschaus, U.S.A. (shared with E.B. Lewis, U.S.A., and C. Nusslein-Volhard, Germany) ......do NICHD Alfred G. Gilman, U.S.A. (shared with M. Rodbell, U.S.A.) .....do NIGMS, NINDS Martin Rodbell, U.S.A. (shared with A.G. Gilman, U.S.A.) ......do NIEHS, NIDDK George A. Olah, U.S.A. Chemistry NCI, NIGMS Phillip A. Sharp, U.S.A. (shared with R. Roberts, U.K.) Physiology or medicine NIGMS, NCI, NIAID, DRS, NCRR Richard Roberts, U.K. (shared with P.A. Sharp, U.S.A.) ......do NCRR, NLM, NCHGR, NCI, NIGMS Kary B. Mullis, U.S.A. (shared with M. Smith, Canada) Chemistry NHLBI, NIAID, NIGMS

16. NIH: About: NIH Almanac: Nobel Laureates nobel Laureates Read about the NIH Scientists who have won nobel prizes. Laureate,Field, Year, Supporting NIH Institute(s). michael S. brown, USA (shared http://www.nih.gov/about/almanac/nobel/

Home About NIH NIH Almanac About the Almanac ... Past Issues Nobel Laureates Read about the NIH Scientists who have won Nobel prizes. Laureate Field Year Supporting NIH Institute(s) Leland H. Hartwell, U.S.A. (shared with P.M. Nurse and R.T. Hunt, U.K.) Physiology or medicine NIGMS, NCI, NCRR K. Barry Sharpless, U.S.A. (shared with W.S. Knowles, U.S.A. and R. Noyori, Japan) Chemistry NIGMS, NHLBI Paul Greengard, U.S.A. (shared with E. Kandel, U.S.A. and A. Carlsson, Sweden) Physiology or medicine NIMH, NIA, NIDA, NINDS, NIAAA, NHLBI, NIAMS Erik R. Kandel, U.S.A. (shared with P. Greengard, U.S.A. and A. Carlsson, Sweden) " NIMH, NIGMS, NINDS, NCRR James J. Heckman, U.S.A. (shared with D. McFadden, U.S.A.) Economic sciences NICHD, NIMH Daniel L. McFadden, U.S.A. (shared with J. Heckman, U.S.A.) " NIA Günter Blobel, U.S.A. Physiology or medicine NIGMS, NCI Robert Furchgott, U.S.A. (shared with L. Ignarro and F. Murad, U.S.A.) Physiology or medicine NIGMS, NHLBI, NINDS

17. Premios Nobel De Medicina Premios nobel de Medicina. Año, Tema, Ganador. ANTICUERPOS MONOCLONALES http//www.bl.fcen.uba.ar/Milstein.pdf.1985, brown, michael S.; Goldstein, Joseph L. http://fai.unne.edu.ar/biologia/nobeles/nobelmed.htm

Premios Nobel de Medicina Tema Ganador Behring, Emil Adolf Von Ross, Sir Ronald Finsen, Niels Ryberg Pavlov, Ivan Petrovich Koch, Robert Cajal, Santiago Ramon Y.; Golgi, Camillo Laveran, Charles Louis Alphonse Ehrlich, Paul; Metchnikoff, Ilya Ilyich Kocher, Emil Theodor Kossel, Albrecht Gullstrand, Allvar Carrel, Alexis Richet, Charles Robert Barany, Robert Bordet, Jules Krogh, Schack August Steenberger Hill, Sir Archibald Vivian; Meyerhof, Otto Fritz; Banting, Sir Frederick Grant; Macleod, John James Richard; Einthoven, Willem; Fibiger, Johannes Andreas Grib Wagner-Jauregg, Julius Nicolle, Charles Jules Henri Eijkman, Christiaan; Hopkins, Sir Frederick Gowland Landsteiner, Karl Warburg, Otto Heinrich Adrian, Lord Edgar Douglas; Sherrington, Sir Charles Scott Morgan, Thomas Hunt Minot, George Richards; Murphy, William Parry; Whipple, George Hoyt Spemann, Hans Dale, Sir Henry Hallett; Loewi, Otto Nagyrapolt, Albert Szent-Gyorgyi Von Heymans, Corneille Jean Francois Domagk, Gerhard Dam, Henrik Carl Peter; Doisy, Edward Adelbert Erlanger, Joseph; Gasser, Herbert Spencer

18. Nobel Prize Winners Support Basic Science Americans have been awarded more than onehalf of all nobel Prizes in physics, chemistryand medicine since 1945. Sidney Altman, Ph.D., michael S. brown, Ph.D http://www.sdsc.edu/SDSCwire/v2.13/nobelists.html

Nobel Prize Winners Seek Stronger Support for Basic Science The American Institute of Physics Bulletin of Science Policy News Number 101: June 26, 1996 The letter, dated June 19, follows: "Dear President Clinton and Members of Congress: "As men and women who have helped to shape the modern scientific age and who care deeply about the future of our nation, we urge you to reaffirm the fundamental role of the federal government in supporting basic scientific research. "Americans have been awarded more than one-half of all Nobel Prizes in physics, chemistry and medicine since 1945. This impressive success is no accident, but the result of a firm and consistent commitment by the federal government to basic science research at our universities. Our nation's policymakers and public have been prudent investors because their support has paid off in tremendous ways. "America's investment in research over the last fifty years has been a vital source of our economic and political strength around the world, as well as the quality of life Americans enjoy at home. The polio vaccine, computers, jet propulsion and disease resistant grains and vegetables are some of the thousands of advances pioneered at our universities that have had dramatic benefits for our health, economy, security and quality of life. "New and equally breathtaking advances may be just around the corner. Genetic research, for example, gives promise of better treatments for Alzheimer's, cancer and other diseases. Lighter and stronger composite materials may be developed with important applications in transportation, medicine and the military. Continuing support for university-based research will not only pave the way for these important breakthroughs, but will also train the next generation of pioneers and Nobelists.

19. The Distinguished Alumni Award - School Of Arts & Sciences At Penn and Sciences' 199798 Distinguished Alumni Awards were presented to michael S. brown,C'62 Southwestern Medical School, and winner of the 1985 nobel Prize in http://www.sas.upenn.edu/home/views/brownshore.html

The College at Penn The Graduate Division The College of General Studies SAS Home ... Distinguished Alumni Award Michael S. Brown, C'62, M'66, HON'86, and William H. Shore, C'77 SAS Dean Samuel Preston (left) chats with Distinguished Alumni Award winngers William Shore (center) and Michael S. Brown (right) The School of Arts and Sciences' 1997-98 Distinguished Alumni Awards were presented to Michael S. Brown, C'62, M'66, HON'86, the Paul J. Thomas Professor of Medicine and Genetics, director of the Jonsson Center for Molecular Genetics at the University of Texas Southwestern Medical School, and winner of the 1985 Nobel Prize in Physiology or Medicine; and to William H. Shore, C'77, founder and executive director of Share Our Strength, an anti-hunger organization. Dr. Brown was recognized for his achievements in the life sciences. Mr. Shore was recognized for his achievements in community service. School of Arts and Sciences

20. Penn SAS Spring 1998 Distinguished Alumni Awards Dean Samuel H. Preston presented the 1998 SAS DistinguishedAlumni Awards to nobel Prizewinning scientist michael S. brown, MD, C http://www.sas.upenn.edu/sasalum/newsltr/spring98/oncampus.html

On Campus Michael Brown and William Shore Are Honored with SAS Distinguished Alumni Awards Dean Samuel H. Preston presented the 1998 SAS Distinguished Alumni Awards to Nobel Prize-winning scientist Michael S. Brown, M.D., C'62, M'66, Hon'86, and to antihunger activist William Shore, C'77. The awards were presented at the Society of Arts and Sciences dinner in March. Brown, the Paul J. Thomas Professor of Medicine and Genetics and director of the Jonsson Center for Molecular Genetics at the University of Texas Southwestern Medical School, received the Nobel Prize in 1985 with Dr. Joseph L. Goldstein for medical discoveries that revolutionized the treatment of diseases caused by high cholesterol levels. Dean Preston remarked that "Michael Brown's research has life-saving implications for millions of people worldwide. SAS is proud to honor the intellect and spirit that has made Dr. Brown a world leader in biomedicine." Shore is founder and executive director of Share Our Strength, an antihunger organization. Dean Preston noted that "Bill Shore's commitment to fighting hunger has raised more than $45 million for over 1,000 antihunger groups worldwide. SAS is proud to recognize such innovative humanitarian work." Shore was profiled in the winter 1998 issue of Nominations for the 1999 SAS Distinguished Alumni Award are already being sought. Please send names of nominees, along with a brief account of their accomplishments in the liberal arts, to: Distinguished Alumni Award, 3440 Market Street, Suite 300, University of Pennsylvania, Pennsylvania, PA 19104-3325.

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