41. Science News Nobel Prize Medicine 2001 WA (10/12/01) Three biologists share this year's nobel Prize in the Imperial ResearchCancer Foundation, will share the prize with leland H. hartwell of the http://www.accessexcellence.org/WN/SU/SU102001/nobelbio.html

42. Selected List Of Nobel Prize Laureates, Lectures, Symposia, Etc. 2001 leland H. hartwell - Yeast and Cancer. Press Release - The nobel Prize for2002 2002 - Sydney Brenner, H. Robert Horvitz John E. Sulston - Genetic http://www.geocities.com/jobustamante/Nobel.htm

43. Nobel Medicine Prize nobel Peace Prize for Physiology and Medicine. The nobel Peace Prize for Physiologyand Medicine dates from 1901. 2001, leland H. hartwell R. Timothy Hunt Sir http://www.geocities.com/Axiom43/nobelmedicine.html

44. Komórkowy Nobel - Nowinki Biologiczne - Wirtualny Wszech¶wiat Szukacz. Przeszukaj Wirtualny Wszechswiat Jak zadawac pytania? KomórkowyNobel. leland H. hartwell Zdjecie Ralf Pettersson. http://www.wiw.pl/nowinki/biologia/200110/20011010-001.asp

W iw.pl Na bie¿±co: I nformacje C o nowego Matematyka i przyroda: A stronomia B iologia ... odelowanie rzeczywisto¶ci Humanistyka: F ilozofia H istoria ... ztuka Czytaj: B iblioteka D elta ... ielcy i wiêksi Przydatne: S ³owniki C o i gdzie studiowaæ ... szech¶wiat w obrazkach Jeste¶ tutaj: Wirtualny Wszech¶wiat Informacje Nowinki 2000-2002 Biologia Jeste¶ tutaj nowinka: Komórkowy Nobel autor: Ma³gorzata Yamazaki z dnia: Szukacz Przeszukaj Wirtualny Wszech¶wiat: Jak zadawaæ pytania? Komórkowy Nobel Tegoroczn± Nagrodê Nobla z medycyny i fizjologii przyznano za odkrycie regulatorów cyklu komórkowego. Czyli tych czynników, które decyduj± o tym, czy komórki dziel± siê prawid³owo, czy te¿ ignoruj± wszelkie przepisy bezpieczeñstwa i wpadaj± w podzia³owy amok, rozrastaj±c siê w raka. Noblistami z medycyny w 2001 roku zosta³a trójka uczonych: Leland Hartwell, Paul Nurse i Timothy Hunt. Wszyscy trzej pracuj± w instytucjach prowadz±cych badania nad rakiem. Wszyscy trzej przyczynili siê do ustalenia mechanizmów odpowiedzialnych za przebieg cyklu komórkowego. Dzisiaj ich odkrycia stanowi± podstawowy kanon wiedzy o funkcjonowaniu komórek. Pojêcia wprowadzone przez tych uczonych s± powszechnie u¿ywane w podrêcznikach szkolnych, znaj± je doskonale wszyscy studenci nauk biologicznych. Poznanie przebiegu prawid³owego cyklu ¿yciowego komórki pozwoli³o zrozumieæ przyczyny nieokie³znanych podzia³ów prowadz±cych do powstawania nowotworów. Tym samym za¶ otworzy³o drogi poszukiwañ nowych metod walki rakiem. Leland H. Hartwell

45. Nobel Prize For Medicine nobel Prize for Medicine Name, Year, The Work. leland H. hartwell, USA R. Timothy(Tim) Hunt, Great Britain Sir Paul M. Nurse, Great Britain, 2001, for their http://www.planet101.com/nobel_medicine.htm

Nobel Prize for Medicine Name Year The Work Leland H. Hartwell , USA R. Timothy (Tim) Hunt , Great Britain Sir Paul M. Nurse , Great Britain for their discoveries of key regulators of the cell cycle" Arvid Carlsson, Paul Greengard and Eric Kandel signal transduction in the nervous system Günter Blobel , USA (born Germany) "proteins have intrinsic signals that govern their transport and localization in the cell" Robert F Furchgott , USA Louis J Ignarro Ferid Murad "nitric oxide as a signalling molecule in the cardiovascular system" PRUSINER, STANLEY B., U.S.A "for his discovery of Prions - a new biological principle of infection" DOHERTY, PETER C., Australia ZINKERNAGEL, ROLF M., Switzerland "for their discoveries concering the specificity of the cell mediated immune defence" LEWIS, EDWARD B., U.S.A NÜSSLEIN-VOLHARD, CHRISTIANE, Germany WIESCHAUS, ERIC F., U.S.A. "for their discoveries concerning the genetic control of early embryonic development" GILMAN, ALFRED G., U.S.A

46. The Scientist - Cell Cycle Control Giants Win Nobel on which today's knowledge of cell cycle is built, American leland H. hartwell ofthe of the Imperial Cancer Research Fund, will receive the nobel Prize for http://www.the-scientist.com/yr2001/oct/maher_p12_011029.html

The Scientist 15[21]:12, Oct. 29, 2001 NEWS Cell Cycle Control Giants Win Nobel Though major contributors are overlooked, a field celebrates an honor E-mail article By Brendan A. Maher Rest, synthesize, divide: The complex and delicate system controlling the life cycles of a cell has long fascinated scientists, and it may open the door to new cancer therapeutics and detection techniques. For their epochal work on which today's knowledge of cell cycle is built, American Leland H. Hartwell of the Fred Hutchinson Cancer Research Center, and Britons R. Timothy Hunt and Sir Paul M. Nurse of the Imperial Cancer Research Fund, will receive the Nobel Prize for physiology or medicine this December, on the 100th anniversary of the Nobels. "The prize recognizes the confluence of two different approaches to learning about the molecular machinery regulating the cell cycle," says Ira Herskowitz , professor in the department of biochemistry and biophysics at the University of California, San Francisco. The story of this convergence starts with Hartwell, a man whose discoveries rival baked bread, beer, and wine as yeast's greatest contribution to mankind. While screening for temperature-sensitive mutants in the yeast Saccharomyces cerevisiae in the 1960s and '70s, Hartwell identified a slew of genes that, in mutant form, arrest mitosis.

47. Encyclopædia Britannica the 2001 nobel Prize for Physiology or Medicine with R. Timothy Hunt and Sir PaulM. Nurse. To cite this page MLA style hartwell, leland H.. Britannica http://www.britannica.com/ebc/article?eu=410004

48. Taipei Times - Archives nobel laureate leland H. hartwell will help promote biomedical research cooperationbetween Taiwan and the US, National Science Council Chairman Wei Che-ho http://taipeitimes.com/News/taiwan/archives/2002/10/25/176985

Fri, Oct 25, 2002 News Editorials Industry eStreet Education Classified 61320043 visits Front Page Taiwan News Editorials Sports ... More in Taiwan News Advertising Back Issue Full List Subscribe FAQ Contact Us Search last 2 months (case-sensitive) Advanced Search Print version Mail this link Nobel laureate promotes research efforts BIOMEDICAL RESEARCH: The National Science Council says Leland H. Hartwell is visiting Taipei to discuss cooperation possibilities between Taiwan and leading institutes in the US By Chiu Yu-Tzu STAFF REPORTER Friday, Oct 25, 2002,Page 2 Nobel Laureate Lee Hartwell shakes hands with National Science Council Chairman Wei Che-ho yesterday. Dr. Chen Ding-shinn of National Taiwan University Hospital accompanied Hartwell to his meeting with Wei. PHOTO: CHEN CHENG-CHANG, TAIPEI TIMES Nobel laureate Leland H. Hartwell will help promote biomedical research cooperation between Tai-wan and the US, National Science Council Chairman Wei Che-ho ( Q­õ©M ) said yesterday.

49. Caltech Nobel And Crafoord Laureates nobel Laureates–29 winners (17 alumni), 30 prizes Name. Field. Year. Chemistry.1999. Faculty. leland H. hartwell, BS '61. Physiology or Medicine. 2001. http://www.caltech.edu/nobel-crafoord/

50. Nobel Prize In Physiology Or Medicine - Wikipedia Source http//www.nobel.se/medicine/laureates/index.html. Blobel 2000 Arvid Carlsson,Paul Greengard, Eric R Kandel 2001 leland H. hartwell, R. Timothy Hunt http://www.wikipedia.org/wiki/Nobel_Prize/Physiology_or_medicine

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51. Nobel Prizes In Medicine And Physiology nobel Prizes in Medicine and Physiology. 1107) for their discoveries concerning signaltransduction in the nervous system 2001 leland H. hartwell (USA, *1939 http://userpage.chemie.fu-berlin.de/diverse/bib/nobel_medizin_e.html

Nobel Prizes in Medicine and Physiology Deutsche Version (List, not checked) E. A. v. Behring (Germany) Sir R. Ross (United Kingdom) N. R. Finsen (Denmark) I. P. Pawlow (Russia) R. Koch (Germany) C. Golgi (Italy) (Spain) Ch. L. A. Laveran (France) P. Ehrlich (Germany) I. Metschnikow (France, Russia) Th. Kocher (Switzerland) A. Kassel (Germany) A. Gullstrand (Sweden) A. Carrel (USA, France) Ch. Richet (France) (Austria) J. Bordet (Belgium) A. Krogh (Denmark) A. V. Hill (United Kingdom) O. Meyerhof (Germany) F. G. Banting (Canada) J. J. R. Macleod (Canada) W. Einthoven (Netherlands) J. Fibiger (Denmark) J. Wagner-Jauregg (Austria) Ch. Nicolle (France) Chr. Eijkman (Netherlands) Sir F.G. Hopkins (United Kingdom) K. Landsteiner (USA, Austria) O. H. Warburg (Germany) Ch. S. Sherrington (United Kingdom) E.D. Adrian (United Kingdom) Th. H. Morgan (USA) G. R. Minot (USA) W. P. Murphy (USA) G.H. Whipple (USA) H. Spemann (Germany) Sir H.H. Dale (United Kingdom) Otto Loewi (Austria, 1873-06-03 - 1961-12-25) (Hungary) C. Heymans (Belgium) G. Domagk

52. CNN.com - Nobel Prize Winners 'in Shock' - October 8, 2001 and Paul M. Nurse, who won the prize with American researcher leland H. hartwell,added that m not sure we really believe it but it's on the (nobel) web site http://www.cnn.com/2001/WORLD/europe/10/08/nobel.prize/

MAIN PAGE WORLD U.S. WEATHER ... ABOUT US/HELP CNN TV what's on show transcripts CNN Headline News CNN International EDITIONS CNN.com Asia CNN.com Europe CNNenEspanol.com CNNArabic.com ... set your edition Languages Spanish Portuguese German Italian Korean Arabic Japanese Time, Inc. Time.com People Fortune EW InStyle Business 2.0 Nobel Prize winners 'in shock' LONDON, England The winners of the Nobel Prize for medicine said they were "bowled over" by their award for ground-breaking new cancer research. British scientists R.Timothy Hunt and Paul M. Nurse, who won the prize with American researcher Leland H. Hartwell, added that they were still reeling from shock and disbelief at a hastily arranged press conference in the UK. "I'm not sure we really believe it but it's on the (Nobel) web site now," Hunt told Reuters news agency, the first of the pair to hear about the honour. Nurse heard the news after he was pulled out of a meeting and told to turn on his mobile phone. The 50 professors of Stockholm's Karolinska Institute, which makes up the Nobel Assembly that votes for the winner of the physiology or medicine award, announced the $1 million prize on Monday. When asked what they would do with the prize money, 58-year-old Hunt said he would pay off the mortgage but Nurse, six years his junior, had something else in mind.

53. CNN.com STOCKHOLM, Sweden An American researcher and two British scientists have wonthe nobel Prize for medicine. US researcher leland H. hartwell and British http://www.cnn.com/SPECIALS/2001/nobel.100/medicine.story.html

HOME OVERVIEW PROFILE: ANNAN PURSUIT OF PEACE ... RESOURCES Cancer team wins the Nobel Prize in medicine From top, Hartwell, Hunt and Nurse STOCKHOLM, Sweden An American researcher and two British scientists have won the Nobel Prize for medicine. U.S. researcher Leland H. Hartwell and British scientists R. Timothy Hunt and Paul M. Nurse have been awarded the prize for key discoveries in the nature of cancer cell development. The 50 professors of Stockholm's Karolinska Institute, which makes up the Nobel Assembly that votes for the winner of the physiology or medicine, announced the $1 million prize on Monday. The assembly said the research "may in the long term...open new principles for cancer therapy," The Associated Press reported. The human body is made up of billions of cells that divide as the body grows. Cancer develops when some cells start to divide in an abnormal way. The award-winning team made crucial breakthroughs in understanding how cells control their division. Hartwell, born in 1939, works at the Fred Hutchinson Cancer Research Centre in Seattle, capital of the north-west U.S. state of Washington. Hunt and Nurse both work at the U.K.'s Imperial Cancer Research Fund in London. Spokeswoman Dawn Boyall told AP that Hunt and Nurse were both "absolutely delighted."

54. Forum Cyber News - Edisi 1029 - Iptek Nobel 2001 Penghargaan nobel bidang kedokteran diberikan kepada leland H. hartwell,Timothy Hunt, dan Paul M. Nurse. Ketiganya melakukan studi http://www.forum.co.id/arsip/1029/Iptek.htm

55. VietReader! Khoa Hoc bào, có th? d?n d?n nh?ng tr? li?u m?i d?i v? leland H. hartwell (Gi?i nobel Lý sinh / Y h?c 2001). http://www.vietreader.com/khoahoc/index.php

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56. The World-Wide Web Virtual Library: Physiology & Biophysics (Biosciences) The 2001 nobel Prize in Physiology or Medicine was awarded this morning to Lee hartwellof the Fred Hutchinson Cancer leland H. hartwell is President http://physiology.med.cornell.edu/WWWVL/PhysioWeb.html

Biosciences A component of The World-Wide Web Virtual Library Maintained by The Department of Physiology and Biophysics at Cornell University Medical College 2001 Nobel Prize in Physiology or Medicine Awarded to Lee Hartwell, Tim Hunt, and Paul Nurse 2001 Nobel Prize to: Lee Hartwell Tim Hunt Paul Nurse 8 October 2001 The 2001 Nobel Prize in Physiology or Medicine was awarded this morning to Lee Hartwell of the Fred Hutchinson Cancer Research Center in Seattle, and to Tim Hunt and Paul M. Nurse of the Imperial Cancer Research Fund, London, all for their work on the discovery ofand interactions betweenCDCs, cyclins and cyclin dependent kinases, key regulators of the cell cycle. This work is fundamental to understanding processes of cell growth, division, and regulation, with implications for cancer and its control. Leland H. Hartwell is President and Director of the Fred Hutchinson CRC . Much of his work was carried out at the University of Washington , also in Seattle, where he is Professor of Genetics and Adjunct Professor of Medicine. He is a member of the National Acadmey of Sciences and a prior award winner of Brandeis' Rosenstiel Award, MSKCC's Katherine Berkan Judd Award, Columbia's Louisa Gross Horwitz Award, and the Albert Lasker Basic Medical Research Award. Sir Paul Nurse, FRS, Director-General of the

57. The Nobel Prize 2001 ? ?(leland H. hartwell), ? (Timothy Hunt),? (Sir Paul M. Nurse) 2000 ? (Arvid Carlsson), ? http://home.megapass.co.kr/~jayleen/medicine/medi-index.htm

ij·Ñ¶óÀÎÀÇÇבּ¸¼ÒÀÇ »ý¸®ÇÐ ÀÇÇлó ¸Þ´Þ¿¡´Â ÀÇÇÐÀÇ ½ÅÀÌ ¹«¸­ À§¿¡ ¥À» Æîijõ°í ¼Ò³à ȯÀÚÀÇ °¥ÁõÀ» ´Þ·¡ÁÖ±â À§ÇØ ±×¸©¿¡´Ù ¹ÙÀ§¿¡¼­ Èê·¯ ³ª¿À´Â ¹°À» ¹Þ°í ÀÖ´Â ¸ð½ÀÀÌ »õ°ÜÁ® ÀÖ´Ù. ÁÖÀ§¿¡´Â º£¸£±æ¸®¿ì½ºÀÇ '¾ÆÀ̳׾ƽº'¿¡¼­ Àοë¶õ ¶óƾ¾î ±¸Àý 'Inventas vitam juvat excoluisse per artes'°¡ »õ°ÜÁ® Àִµ¥ '±×¸®°í »õ·Î ¹ß°ßÇÑ Áö¹è·Î Áö»ó¿¡¼­ÀÇ »îÀ» ´õ ³´°Ô ¸¸µç ±×µé'À̶ó´Â ¶æÀÌ´Ù. Leland H. Hartwell), Ƽ¸ð½ ÇåÆ®(Timothy Hunt), Æú ³Ê½º(Sir Paul M. Nurse) Arvid Carlsson), Æú ±×¸°°¡µå(Paul Greengard), ¿¡¸¯ Ä˵é(Eric R. Kandel) Robert F. Furchgott), ·çÀ̽º À̱׳ª·Î(Louis J. Ignarro), Æ丮µå ¹Â¶óµå(Ferid Murad) Stanley B. Prusiner) Peter C. Doherty), ·ÑÇÁ ĪĿ³ª°Ö(Rolf M. Zinkernagel) Alfred G. Gilman), ¸¶Æ¾ ·Îµåº§(Martin Rodbell) Richard J. Roberts), Çʸ³ »þÇÁ(Phillip A. Sharp) Edmond H. Fischer), ¿¡µåÀ© Å©·¹ºê½º(Edwin G. Krebs) Erwin Neher), º£¸£Æ® ÀÚÅ©¸¸(Bert Sakmann) Joseph E. Murray), µµ³Î Åä¸Ó½º(E. Donnall Thomas) J. Michael Bishop), ÇØ·Ñµå ¹Ù¸Ó½º(Harold E. Varmus) Sir James W. Black), °ÅÅõ¸£µå ¿¤¸®¿Â(Gertrude B. Elion),Á¶Áö È÷Ī½º( George H. Hitchings) Susumu Tonegawa) Stanley Cohen), ¸®Å¸ ·¹ºñ ¸óÅ»¸®Ä¡(Rita Levi-Montalcini)

58. AMC - Carta Informativa Octubre-diciembre 2001 Translate this page la labor de los médicos británicos R. Timothy Hunt y Paul M. Nurse, junto conel estadounidense leland H. hartwell, con el Premio nobel de Fisiología y http://www.amc.unam.mx/Noticias/Carta/carta33/c33htm/carta33-19.html

Este año el galardón cumple un centenario Conceden los Premios Nobel 2001 en el área de ciencias El condensado de Bose Einstein, la quilaridad y el conocimiento del ciclo celular fueron las investigaciones reconocidas Este año, se cumplen 100 años de la entrega de los premios de mayor reconocimiento científico en el ámbito internacional: los Premios Nobel, creados por iniciativa del investigador y empresario sueco Alfred Nobel y que han sido otorgados a hombres y mujeres que con sus aportaciones al conocimiento han beneficiado a la humanidad. En esta ocasión, el Instituto Kalolinska y la Fundación Nobel reconocieron la labor de los médicos británicos R. Timothy Hunt y Paul M. Nurse, junto con el estadounidense Leland H. Hartwell, con el Premio Nobel de Fisiología y Medicina 2001, por sus descubrimientos sobre "las claves reguladoras del ciclo celular", que han abierto nuevas vías para el tratamiento de las enfermedades cancerígenas. El Premio Nobel de Física 2001 se concedió a los estadounidenses Eric A. Cornell y Carl Wieman, y al alemán Wolfgang Ketterle, por obtener un nuevo estado de la materia denominado "Condensado Bose Einstein" (BEC por sus siglas en inglés).

59. Caltech Nobel And Crafoord Laureates nobel Laureates NAME / DEGREE, FIELD, YEAR. Ahmed H. Zewail, chemistry, 1999.leland H. hartwell BS '61, physiology or medicine, 2001. Thomas Hunt Morgan. http://prfmp.caltech.edu/catalog/02_03/geninfo/nobel2.html

60. Premio Nobel De Medicina Y Fisiología 2001 Translate this page de los seis premios que concede este año, el premio nobel en Medicina Paul M. Nursey R. Timothy (Tim) Hunt, y al estadounidense leland H. hartwell, por sus http://www.ciencias.uma.es/publicaciones/encuentros/ENCUENTROS73/nobel2001.htm

Premio Nobel de Medicina y Fisiología 2001 La coordinación precisa de las distintas fases del ciclo celular es esencial para todos los organismos eucariotas. Las fases tienen que seguirse en el orden correcto y una fase tiene que estar completada antes de que comience la siguiente. Errores en la coordinación podrían provocar alteraciones cromosómicas, tales como pérdidas de cromosomas enteros o partes de los mismos, reordenación o distribución desigual de cromosomas a las células hijas, etc. Este tipo de alteraciones cromosómicas se observa a menudo en células cancerosas. Los premiados este año con el Nobel de Medicina han hecho importantes descubrimientos sobre los mecanismos de control del ciclo celular, identificando moléculas clave que regulan el ciclo celular en todos los organismos eucariotas. El norteamericano Leland Hartwell (nacido en 1939), del Fred Hutchinson Cancer Research Center de Seattle, ha sido galardonado por su descubrimiento de una clase específica de genes que controlan el ciclo celular. Uno de esos genes, denominado start El británico Paul Nurse (nacido en 1949), del Imperial Cancer Research Fund de Londres, identificó, clonó y caracterizó, mediante métodos genéticos y moleculares, uno de los factores clave del ciclo celular, la quinasa dependiente de ciclina (CDK), la cual conduce a la célula a través del ciclo celular mediante la fosforilación de otras proteínas. También demostró que la función de la CDK está muy conservada durante la evolución.

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