1. George H. Hitchings Winner Of The 1988 Nobel Prize In Medicine george H. hitchings, a nobel Prize Laureate in Physiology and Medicine,at the nobel Prize Internet Archive. george H. hitchings. http://almaz.com/nobel/medicine/1988c.html

G EORGE H H ITCHINGS 1988 Nobel Laureate in Medicine for their discoveries of important principles for drug treatment. Background Born: 1905 Residence: U.S.A. Affiliation: Wellcome Research Laboratories, Research Triangle Park, NC Book Store Books on the Pharmaceutical Chemistry Featured Internet Links Prize co-recipient: Sir James W. Black Prize co-recipient: Gertrude B. Elion Official award announcement and background Biography Search WWW Search The Nobel Prize Internet Archive Nobel News Links 3 Share Nobel for Medicine Honoring Drug Discoverers Links added by Nobel Internet Archive visitors Winner of The Gairdner Foundation Int'l Award Back to The Nobel Prize Internet Archive Literature Peace ... Medicine We always welcome your feedback and comments

2. Index Of Nobel Laureates In Medicine ALPHABETICAL LISTING OF nobel PRIZE LAUREATES IN PHYSIOLOGY AND MEDICINE. Name,Year Awarded. Hill, Sir Archibald Vivian, 1922. hitchings, george H. 1988. http://almaz.com/nobel/medicine/alpha.html

ALPHABETICAL LISTING OF NOBEL PRIZE LAUREATES IN PHYSIOLOGY AND MEDICINE Name Year Awarded Adrian, Lord Edgar Douglas Arber, Werner Axelrod, Julius Baltimore, David ... Medicine We always welcome your feedback and comments

3. George H. Hitchings - Autobiography george H. hitchings – Autobiography. building of wooden ships, and my father, georgeHerbert hitchings to the management, which then became hitchings and Joyce http://www.nobel.se/medicine/laureates/1988/hitchings-autobio.html

My forebears all came from the United Kingdom. On my father's side, they migrated from London and County Derry in Northern Ireland to Londonderry, New Hampshire. When the American Revolution came, they, as loyalists, moved on to Canada. My father, grandfather and great-grandfather were born in St. Andrews, New Brunswick. In 1865, my grandfather, Andrew Hitchings, moved his family to Eureka, California. Andrew was a skilled craftsman in the building of wooden ships, and my father, George Herbert Hitchings, Sr., followed in his footsteps, eventually becoming a marine architect and master builder. On my mother's side, Scottish and English prevailed. The first American was one Thomas Littlejohn from near Edinburgh, who came to the New World about 1735. His descendants, including Shaws, Eldridges and Thomases, moved about in the Maritime Provinces and New England. My maternal grandfather and great-grandfather were descendants of the Matthews family that emigrated twenty-four strong from near Glasgow to Prince Edward Island about 1800. My grandfather, Peter Matthews, married Sara Elizabeth Eldridge, and my mother, Lillian Matthews, was born in Maine. In 1875, my grandfather moved his family across the United States. He, too, was a shipbuilder and settled in Eureka. My mother and father met and were married in Eureka, and my two sisters were born there. About 1897, Peter Matthews established a shipyard in Hoquiam, Washington, to build lumber carriers for the E.K. Wood Lumber Company. The company built several schooners a year. When Peter Matthews died, my father succeeded to the management, which then became Hitchings and Joyce. Later, my father was master builder and supervisor in Bellingham, Washington, and Coos Bay, Oregon, and between times he engaged in marine architecture. He worked in the period between sail and steam and was especially noted for the design of the transition vessel, the steam schooner, which had a wooden hull and was steam propelled.

4. Medicine 1988 The nobel Prize in Physiology or Medicine 1988. for treatment . SirJames W. Black, Gertrude B. Elion, george H. hitchings. 1 http://www.nobel.se/medicine/laureates/1988/

The Nobel Prize in Physiology or Medicine 1988 "for their discoveries of important principles for drug treatment" Sir James W. Black Gertrude B. Elion George H. Hitchings 1/3 of the prize 1/3 of the prize 1/3 of the prize United Kingdom USA USA King's College Hospital Medical School, University of London London, United Kingdom Wellcome Research Laboratories Research Triangle Park, NC, USA Wellcome Research Laboratories Research Triangle Park, NC, USA b. 1924 b. 1918 d. 1999 b. 1905 d. 1998 The Nobel Prize in Physiology or Medicine 1988 Press Release Presentation Speech Sir James W. Black ... Banquet Speech The 1988 Prize in: Physics Chemistry Physiology or Medicine Literature ... Economic Sciences Find a Laureate: Last modified June 16, 2000 The Official Web Site of The Nobel Foundation

5. Hitchings, George Herbert george H. hitchings reacting to questions at a press conference after it wasannounced he had won the nobel Prize for Physiology or Medicine, 1988. http://www.britannica.com/nobel/micro/272_65.html

Hitchings, George Herbert George H. Hitchings reacting to questions at a press conference after it was announced he had won the Nobel Prize for Physiology or Medicine, 1988 UPI/Corbis-Bettmann (b. April 18, 1905, Hoquiam, Wash., U.S.d. Feb. 27, 1998, Chapel Hill, N.C.), American pharmacologist who, along with Gertrude B. Elion and Sir James W. Black , received the Nobel Prize for Physiology or Medicine in 1988 for their development of drugs that became essential in the treatment of several major diseases. Hitchings received his bachelor's and master's degrees from the University of Washington and earned a Ph.D. in biochemistry at Harvard University in 1933. He taught at Harvard until 1939, and in 1942 he joined the Burroughs Wellcome Laboratories, at which he conducted research until his retirement in 1975. Over a span of nearly 40 years, Hitchings worked with Elion, who was first his assistant and then his colleague in research at Burroughs Wellcome. Together they designed a variety of new drugs that achieved their effects by interfering with the replication or other vital functions of specific pathogens (disease-causing agents). In the 1950s they developed thioguanine and 6-mercaptopurine (6MP), which became important treatments for leukemia. In 1957 their alteration of 6MP produced the compound azathioprine, which proved useful in treating severe rheumatoid arthritis and other autoimmune disorders and in suppressing the body's rejection of transplanted organs. Their new drug allopurinol was an effective treatment for gout. Other important drugs that were developed by Hitchings and Elion include pyrimethamine, an antimalarial agent; trimethoprim, a treatment for urinary and respiratory tract infections; and acyclovir, the first effective treatment for viral herpes.

6. Nobel Prize Winners For Physiology Or Medicine hitchings, george Herbert, US, development of new classes of drugs for combatingdisease. 1992, Fischer, Edmond H. US, discovery of class of enzymes called protein http://www.britannica.com/nobel/table/phymed.html

Year Article Country* Achievement Behring, Emil von Germany work on serum therapy Ross, Sir Ronald U.K. discovery of how malaria enters an organism Finsen, Niels Ryberg Denmark treatment of skin diseases with light Pavlov, Ivan Petrovich Russia work on the physiology of digestion Koch, Robert Germany tuberculosis research Golgi, Camillo Italy work on the structure of the nervous system Spain work on the structure of the nervous system Laveran, Alphonse France discovery of the role of protozoa in diseases Ehrlich, Paul Germany work on immunity Russia work on immunity Kocher, Emil Theodor Switzerland physiology, pathology, and surgery of the thyroid gland Kossel, Albrecht Germany researches in cellular chemistry Gullstrand, Allvar Sweden work on dioptrics of the eye Carrel, Alexis France work on vascular suture; transplantation of organs Richet, Charles France work on anaphylaxis Austria-Hungary work on vestibular apparatus Bordet, Jules Belgium work on immunity factors in blood serum Krogh, August Denmark discovery of capillary motor-regulating mechanism Hill, A.V.

7. George H. Hitchings (Infoplease.com)Category Reference Encyclopedias Infoplease.com Biographies G...... george H. hitchings Age 92. 1988 nobel Prize winner for pharmaceutical researchthat led to the creation of drugs to treat lukemia and other diseases of the http://www.infoplease.com/ipa/A0758239.html

The # 1 wireless color security cam! Ultimate home movie ! Genuine Indian and Asian astrology reports and consultations by reputed Vedic Astrologers. Step-by-step guide to finding money for a growing business All Infoplease All Almanacs General Entertainment Sports Biographies Dictionary Encyclopedia Infoplease Home Almanacs Atlas Dictionary ... Fact Monster Kids' reference Info:Daily Fun facts Homework Center Newsletter You've got info! Help Site Map Visit related sites from: Family Education Network Biography Noteworthy People 1998 Deaths ... G - L George H. Hitchings Age: 1988 Nobel Prize winner for pharmaceutical research that led to the creation of drugs to treat lukemia and other diseases of the immune system. Died: Feb. 27, 1998. Sir Francis Harry Hinsley G - L Chris Hitopoulos Search Infoplease Info search tips Search Biographies Bio search tips About Us Contact Us Link to Infoplease ... Privacy

8. Nobel Prizes (table) nobel Prizes. Johann Deisenhofer Robert Huber Hartmut Michel, Leon M. Lederman MelvinSchwartz Jack Steinberger, Gertrude B. Elion george H. hitchings Sir James http://www.infoplease.com/ce6/sci/A0835783.html

Reduce your family medical costs by up to 60% now! Oral health..Save up to 60% on dental care. Easy Medical Diagnosis..stop smoking! All Infoplease All Almanacs General Entertainment Sports Biographies Dictionary Encyclopedia Infoplease Home Almanacs Atlas Dictionary ... Fact Monster Kids' reference Info:Daily Fun facts Homework Center Newsletter You've got info! Help Site Map Visit related sites from: Family Education Network Encyclopedia Nobel Prizes Year Peace Chemistry Physics Physiology or Medicine Literature J. H. van't Hoff W. C. Roentgen E. A. von Behring R. F. A. Sully-Prudhomme Emil Fischer H. A. Lorentz Pieter Zeeman Sir Ronald Ross Theodor Mommsen Sir William R. Cremer S. A. Arrhenius A. H. Becquerel Pierre Curie Marie S. Curie N. R. Finsen Institute of International Law Sir William Ramsay J. W. S. Rayleigh Ivan P. Pavlov Baroness Bertha von Suttner Adolf von Baeyer Philipp Lenard Robert Koch Henryk Sienkiewicz Theodore Roosevelt Henri Moissan Sir Joseph Thomson E. T. Moneta Louis Renault Eduard Buchner A. A. Michelson C. I. A. Laveran Rudyard Kipling K. P. Arnoldson Fredrik Bajer

9. After The Prize: The UW's Nobel Laureates Our first laureate, george J. Stigler, `31, who won the 1982 nobel Prize in economics,died in 1991. Editor's note george H. hitchings died on February 27 http://www.washington.edu/alumni/columns/march98/nobels1.html

Six UW Nobel Laureates Talk About the Day They Wonand the Life After. by Rebecca Hughes Seven men from the University of Washingtonfour professors and three alumnihave won the Nobel Prize . Bombarded by the media, showered with invitations and suddenly given thousands of dollars in prize money, the time of the announcement is a heady experience. But we wondered what happened next. Do you live happily ever after, both personally and professionally? Or should you be careful what you wish for, lest your dreams come true? Columns tracked down the half-dozen UW laureates still living to find out. Our four faculty members continue to live in Seattle: Physics Professor Hans G. Dehmelt, who shared the 1989 prize in physics; Medicine and Oncology Professor Emeritus E. Donnall Thomas, who shared the 1990 prize in medicine for his work at the Fred Hutchinson Cancer Research Center; and Pharmacology and Biochemistry Professor Emeritus Edwin G. Krebs and Biochemistry Professor Emeritus Edmond H. Fischer, who together shared the 1992 in medicine. Surprisingly, the two living alumni laureates live only a few miles apart in North Carolina: George H. Hitchings, `27, who shared the 1988 prize in medicine; and Martin Rodbell, `54, who shared the 1994 prize in medicine. Our first laureate, George J. Stigler, `31, who won the 1982 Nobel Prize in economics, died in 1991.

10. George Hitchings Click here to read it. For more information, at other Web sites GeorgeH. hitchings, Jr. — autobiography from the nobel eMuseum. http://www.chemheritage.org/EducationalServices/pharm/chemo/readings/hitch.htm

George Hitchings Pharmaceutical Achiever The lives of George Hitchings Jr. and Gertrude Belle Elion intersected in 1944 when Hitchings, working at Burroughs Wellcome in New York, hired Elion to work with him as an assistant in the biochemistry department of the Wellcome Research Laboratories. For the next 30 years the pair collaborated on drug research that brought them both a Nobel Prize in 1988, for "important principles of drug development." Hitchings was born on the Olympic Peninsula in Washington state in 1905. As with Elion, the death of a close family member combined with an admiration for science led Hitchings to set his sights on a career in the medical and chemical sciences. "My father died after a prolonged illness when I was twelve years old," Hitchings once wrote. "The deep impression made by this event turned my thoughts toward medicine. This objective shaped my selection of courses in high school and expressed itself when I was salutatorian at my class graduation. I chose the life of [Louis] Pasteur as the subject for my oration. The blending of Pasteur's basic research and practical results remained a goal throughout my career." DNA's double-helical structure.

11. George Hitchings - Teacher's Guide For more information, at other Web sites george H. hitchings, Jr.— autobiography from the nobel eMuseum. The Reconstructors http://www.chemheritage.org/EducationalServices/pharm/tg/chemo/readings/hitch.ht

George Hitchings Pharmaceutical Achiever Using the Biographies This reading tells the story of George Hitchings, one of the developers of "rational drug design" along with Gertrude Elion. Hitchings and Elion were awarded The Nobel Prize in Medicine or Physiology in 1988. For more information, at other Web sites... George H. Hitchings, Jr. — autobiography from the Nobel e -Museum. The Reconstructors — be the drug discoverer in this postapocalyptic sci-fi drug development game that lets you rediscover the secrets of aspirin in a future world that has lost the knowledge of modern medicine, from Rice University. Relevant National Science Education Standards Science as Inquiry — Students should realize that both Hitchings' and Elion's research began with questions such as How do cells reproduce? then proceeded to questions like What compounds can we use to limit the reproduction of cancer cells? Furthermore, when compounds were found that had some impact on the reproduction of cancer cells, there were still questions to be answered, such as How can we alter the strucutre of this molecule to make it a more effective cancer drug? The students should grasp that it is through scientific experimentation that Hitchings or any other researcher answers the questions facing them. Physical Science — The molecular nature of matter is central to Hitchings' research, especially the concept that altering the structure of a molecule alters its properties, and this is how Hitchings was able to create new molecules to treat cancer. The students should realize it was by a process of gradually altering the molecular structures of drug-candidates was he able to tweak their properties until he arrived at safe and effective anticancer medicines.

12. Premios Nobel De Medicina Premios nobel de Medicina. de importantes principios para el tratamiento condrogas , Black, Sir James W.; Elion, Gertrude B.; hitchings, george H. http://fai.unne.edu.ar/biologia/nobeles/nobelmed.htm

Premios Nobel de Medicina Tema Ganador Behring, Emil Adolf Von Ross, Sir Ronald Finsen, Niels Ryberg Pavlov, Ivan Petrovich Koch, Robert Cajal, Santiago Ramon Y.; Golgi, Camillo Laveran, Charles Louis Alphonse Ehrlich, Paul; Metchnikoff, Ilya Ilyich Kocher, Emil Theodor Kossel, Albrecht Gullstrand, Allvar Carrel, Alexis Richet, Charles Robert Barany, Robert Bordet, Jules Krogh, Schack August Steenberger Hill, Sir Archibald Vivian; Meyerhof, Otto Fritz; Banting, Sir Frederick Grant; Macleod, John James Richard; Einthoven, Willem; Fibiger, Johannes Andreas Grib Wagner-Jauregg, Julius Nicolle, Charles Jules Henri Eijkman, Christiaan; Hopkins, Sir Frederick Gowland Landsteiner, Karl Warburg, Otto Heinrich Adrian, Lord Edgar Douglas; Sherrington, Sir Charles Scott Morgan, Thomas Hunt Minot, George Richards; Murphy, William Parry; Whipple, George Hoyt Spemann, Hans Dale, Sir Henry Hallett; Loewi, Otto Nagyrapolt, Albert Szent-Gyorgyi Von Heymans, Corneille Jean Francois Domagk, Gerhard Dam, Henrik Carl Peter; Doisy, Edward Adelbert Erlanger, Joseph; Gasser, Herbert Spencer

13. Search Results For George A. H. Blake - Encyclopædia Britannica - The Online En The Web's Best Sites. george H. hitchings,Jr nobel Foundation Autobiographyof this American radio astronomer, physicist, and nobel laureate. http://search.britannica.com/search?query=George A. H. Blake

14. Search Results For Jr. Wallace H. White - Encyclopædia Britannica - The Online george H. hitchings,Jr nobel Foundation Autobiography of this Americanradio astronomer, physicist, and nobel laureate. Software http://search.britannica.com/search?query=Jr. Wallace H. White

15. ALPHABETICAL LISTING OF NOBEL PRIZE LAUREATES IN PHYSIOLOGY AND MEDICINE FRONTIERS IN BIOSCIENCE; ALPHABETICAL LISTING OF nobel PRIZE LAUREATES INPHYSIOLOGY AND MEDICINE, Name, Year Awarded. hitchings, george H. 1988. http://www.bioscience.org/urllists/nobelm.htm

FRONTIERS IN BIOSCIENCE; ALPHABETICAL LISTING OF NOBEL PRIZE LAUREATES IN PHYSIOLOGY AND MEDICINE Name Year Awarded Adrian, Lord Edgar Douglas Arber, Werner Axelrod, Julius Baltimore, David ... Zinkernagel, Rolf M.

16. ALPHABETICAL LISTING OF NOBEL PRIZE LAUREATES IN CHEMISTRY Zsigmondy, Richard Adolf, 1925. ALPHABETICAL LISTING OF nobel PRIZE LAUREATES INPHYSIOLOGY AND MEDICINE. hitchings, george H. 1988. Hodgkin, Sir Alan Lloyd, 1963. http://www.bioscience.org/urllists/nobelc.htm

FRONTIERS IN BIOSCIENCE; ALPHABETICAL LISTING OF NOBEL PRIZE LAUREATES IN CHEMISTRY, PHYSIOLOGY AND MEDICINE ALPHABETICAL LISTING OF NOBEL PRIZE LAUREATES IN CHEMISTRY Name Year Awarded Alder, Kurt Altman, Sidney Anfinsen, Christian B. Arrhenius, Svante August ... Zsigmondy, Richard Adolf ALPHABETICAL LISTING OF NOBEL PRIZE LAUREATES IN PHYSIOLOGY AND MEDICINE Name Year Awarded Adrian, Lord Edgar Douglas Arber, Werner Axelrod, Julius Baltimore, David ... Zinkernagel, Rolf M. Source: The Nobel Prize Internet Archive

17. Sigma Xi: The Scientific Research Society: Nobel Laureates About Sigma Xi » Overview » nobel Laureates 1986 Stanley Cohen 1986 Rita LeviMontalcini1988 Gertrude B. Elion 1988 george H. hitchings 1992 Edmond Henri http://www.sigmaxi.org/about/overview/nobel.shtml

Overview Leadership Organization News ... Contact Us About: Overview Leadership Organization News Support Sigma Xi ... Contact Us Search: Site Map Home Overview Physics 1907 Albert Michelson 1921 Albert Einstein 1923 Robert A. Millikan 1925 James Franck 1927 Arthur H. Compton 1936 Carl D. Anderson 1937 Clinton J. Davisson 1938 Enrico Fermi 1939 Ernest O. Lawrence 1943 Otto Stern 1944 Isidor Isaac Rabi 1945 Wolfgang Pauli 1946 Percy Williams Bridgman 1952 Felix Bloch 1952 Edward M. Purcell 1955 Polykarp Kusch 1955 Willis E. Lamb, Jr. 1956 John Bardeen 1956 Walter H. Brattain 1956 William Shockley 1957 Chen Ning Yang 1958 Igor Y. Tamm 1959 Owen Chamberlain 1959 Emilio G. Segre 1960 Donald A. Glaser 1961 Robert Hofstadter 1963 Eugene P. Wigner

18. Premio Nobel De Medicina - Wikipedia Translate this page Ver enlace http//www.nobel.se/medicine/laureates/index.html. Harold E. Varmus 1988Sir James W. Black, Gertrude B. Elion, george H. hitchings 1987 Susumu http://es.wikipedia.org/wiki/Premio_Nobel/Medicina

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19. Nobel Prize In Physiology Or Medicine - Wikipedia Source http//www.nobel.se/medicine/laureates/index.html. 1987 Susumu Tonegawa1988 Sir James W. Black, Gertrude B. Elion, george H. hitchings 1989 J http://www.wikipedia.org/wiki/Nobel_Prize/Physiology_or_medicine

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20. Nobel Prize In Medicine Since 1901 hitchings, george H. http://www.planet101.com/nobel_medi_hist.htm

Nobel Prize in Medicine since 1901 Year Prize Winners Behring, Emil Adolf Von Ross, Sir Ronald Finsen, Niels Ryberg Pavlov, Ivan Petrovich Koch, Robert Cajal, Santiago Ramon Y.; Golgi, Camillo Laveran, Charles Louis Alphonse Ehrlich, Paul; Mechnikov, Ilya Ilyich Kocher, Emil Theodor Kossel, Albrecht Gullstrand, Allvar Carrel, Alexis Richet, Charles Robert Barany, Robert Bordet, Jules Krogh, Schack August Steenberger Hill, Sir Archibald Vivian; Meyerhof, Otto Fritz; Banting, Sir Frederick Grant; Macleod, John James Richard; Einthoven, Willem; Fibiger, Johannes Andreas Grib Wagner-Jauregg, Julius Nicolle, Charles Jules Henri Eijkman, Christiaan; Hopkins, Sir Frederick Gowland Landsteiner, Karl Warburg, Otto Heinrich Adrian, Lord Edgar Douglas; Sherrington, Sir Charles Scott Morgan, Thomas Hunt Minot, George Richards; Murphy, William Parry; Whipple, George Hoyt Spemann, Hans Dale, Sir Henry Hallett; Loewi, Otto Nagyrapolt, Albert Szent-Gyorgyi Von Heymans, Corneille Jean Francois Domagk, Gerhard Dam, Henrik Carl Peter; Doisy, Edward Adelbert Erlanger, Joseph; Gasser, Herbert Spencer

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