41. NACS - News Swedish Academy of Sciences has decided to award the nobel Prize in catalysed hydrogenationreactions and the other half to K. barry sharpless the Scripps http://www.nacatsoc.org/news.asp?NewsID=8

42. Nobel De Chimie : Deux Américains Et Un Japonais Distingués Translate this page Le prix nobel de chimie 2001 a été attribué mercredi à William S. Knowles (Etats-Unis)et Ryoji Noyori (Japon) d'une part, et à K. barry sharpless (Etats http://www.tf1.fr/news/sciences/0,,826087,00.html

Le prix Nobel de chimie 2001 a ©t© adress© mercredi   deux chercheurs am©ricains et un chercheur japonais pour leurs travaux sur le d©veloppement de la synth¨se asym©trique catalytique. Les r©sultats de leurs travaux sont exploit©s notamment pour des antibiotiques et des anti-inflammatoires. OAS_AD('Top'); Accueil tf1.fr Astro Bourse Cin©ma ... SCIENCES L'©pid©mie de pneumonie atypique... Je ne me sens pas concern©(e) Cela m'inqui¨te Vos derniers avis A L'ANTENNE LE SITE DU 13H LCI LIVE TOUS LES JT EN VIDEO Accueil TF1 ... SCIENCES Nobel de chimie : deux Am©ricains et un japonais distingu©s Le prix Nobel de chimie 2001 a ©t© adress© mercredi   deux chercheurs am©ricains et un chercheur japonais pour leurs travaux sur le d©veloppement de la synth¨se asym©trique catalytique. Les r©sultats de leurs travaux sont exploit©s notamment pour des antibiotiques et des anti-inflammatoires. Mis en ligne le 10 octobre 2001 Pour aller plus loin On trouve de tout sur la liste Nobel Les 100 ans du prix Nobel Le prix Nobel de m©decine 2001 attribu©   une ©quipe anglo-am©ricaine Des chercheurs am©ricains et allemand re§oivent le Nobel de physique Le prix Nobel de chimie 2001 a ©t© attribu© mercredi   William S. Knowles (Etats-Unis) et Ryoji Noyori (Japon)

43. Barry K. Sharpless - CIRS sharpless, barry K. is integral now to all research within the sharpless Lab ISI HighlyCited Researchers Database, original member, 2001 2001 nobel Laureate in http://www.cirs.net/researchers/Chemistry/sharpless.htm

SHARPLESS, BARRY K. sharples@scripps.edu W. M. Keck Professor of Chemistry at the The Scripps Research Institute (TSRI), La Jolla, USA. Research interests: The Sharpless Lab pursues useful new reactivity and general methods for selectively controlling chemical reactions. Though the focus has progressed from regio- to stereo- to asymmetric and, now, to connectivity control, the core chemistry remains unchanged: the oxidation of olefins, that single most versatile, powerful and reliable (KBS argues) chemical transformation. The Sharpless Lab was the first academic chemistry group with robotics, and the lesson from the combinatorial numbers game was the primacy of reliability. "Click" chemistry was the Sharpless Lab's response: a set of powerful, virtually 100% reliable, selective reactions for the rapid synthesis of new compounds via heteroatom links (C-X-C). Click chemistry is integral now to all research within the Sharpless Lab. Awards : Allan Day Award , Philadelphia Organic Chemists Club, 1985 Dr. Paul Janssen Prize

44. SignOnSanDiego > News > Science -- Research Is Breakthrough K. barry sharpless, a San Diego chemist whose research led to new methods for makingdrugs and other compounds shared the nobel Prize in chemistry yesterday. http://www.uniontrib.com/news/science/20011011-9999_7m11sharp.html

Advertising Info About Us Contact SignOn Membership ... AP Wire Research is breakthrough Scripps scientist shares award; work led to new manufacturing techniques By Bruce V. Bigelow UNION-TRIBUNE STAFF WRITER October 11, 2001 K. Barry Sharpless, a San Diego chemist whose research led to new methods for making drugs and other compounds shared the Nobel Prize in chemistry yesterday. Sharpless, a scientist at The Scripps Research Institute, shared the prestigious award with William S. Knowles of St. Louis and Ryoji Noyori of Japan's Nagoya University. The three were honored for discovering new types of chemical reactions that could be used to duplicate the highly specific way that nature makes molecules. Nobel winner's enthusiasm is intoxicating Nobel is awesome, but also carries a price Their research led to manufacturing techniques that didn't exist before the 1970s, enabling scientists to produce new types of medicine such as L-dopa, a now-standard treatment for Parkinson's disease. Their work, which dates to the 1960s, also allowed other industries to create purer, more-effective compounds from perfumes and pheromone-based pesticides to flavorings and sweeteners. From the archives: Scripps scientist cited for molecular work Scripps, UCSD top influence list in chemistry

45. Biovitrum Announces The Formation Of Its Scientific Advisory Board K. barry sharpless PhD, barry sharpless is Professor of Chemistry at the ScrippsResearch Institute. In 2001, he was awarded the nobel Prize in Chemistry for http://www.noonanrusso.com/news/view_newsitem.aspx?ItemID=3

46. 65th Anniversary Professors Ryoji Noyori (Japan), K. barry sharpless (USA) and WilliamS. Knowles (USA) shared the nobel Prize in Chemistry 2001. http://www.polyu.edu.hk/cpa/anniversary/event_core_07.htm

Core 65th Anniversary Celebratory Activities «Ø®Õ¤»¤Q¤­©P¦~¬ö©À­«ÂI¼y¯¬¬¡°Ê Date ¤é´Á Event ¬¡°Ê Enquiries ¸Ô±¡¬d¸ß Nobel Laureate Lectures ¿Õ¨©º¸±o¼úªÌÁ¿®y Department of Applied Biology and Chemical Technology À³¥Î¥Íª«¤Î¤Æ¾Ç¬ì§Þ¾Ç¨t Prof. Albert Chan Tel: 2766-5607 Fax: 2364-9932 Professors Ryoji Noyori (Japan), K. Barry Sharpless (USA) and William S. Knowles (USA) shared the Nobel Prize in Chemistry 2001. The Royal Swedish Academy of Sciences has awarded the Prize for their development of catalytic asymmetric synthesis. The achievements of these three chemists are of great importance for academic research, and for the development of new drugs and materials which are being used in many industrial syntheses of pharmaceutical products and other biologically active substances. Professors Ryoji Noyori and K. Barry Sharpless will deliver lectures at 3:00p.m. on 29 April 2002 at Chiang Chen Studio Theatre, PolyU.

47. The 2001 Nobel Prize In Medicine K. barry sharpless shared the 2001 nobel Prize in Chemistry for showing how tobetter control chemical reactions, paving the way for new heart drugs and http://hkscm.atomcreation.com/hkscm_new/escinews/escinews.htm

Science News The 2001 Nobel Prize in Medicine An American scientist, Prof. Leland H. Hartwell, and two British scientists, Sir Paul M. Nurse and Prof. R. Timothy Hunt, shared the 2001 Nobel Prize in Physiology or Medicine for their discoveries of key regulators of the cell cycle and identifications of key molecules that regulate the cell cycle in all eukaryotic organisms, including yeasts, plants, animals and humans beings. All organisms consist of cells that multiply through cell division. In adults there is also an enormous number of continuously dividing cells replacing those dying. Before a cell can divide it has to grow in size, duplicate its chromosomes and separate the chromosomes for exact distribution between the two daughter cells. These different processes are coordinated in the cell cycle. Defects in cell cycle control may lead to the type of chromosome alterations seen in cancer cells. Therefore, the study of cell cycle may open new possibilities for cancer treatment. Prof. Leland H. Hartwell of the Fred Hutchinson Cancer Research Center, Seattle, is awarded for his discoveries of a specific class of genes that control the cell cycle. One of these genes called "start" was found to have a central role in controlling the first step of each cell cycle. Hartwell also introduced the concept "checkpoint", a valuable aid to understanding the cell cycle.

48. Nobel. Chemia. 2001 01, 1720) • Literacki nobel '2001 dla VS Naipaula (1110-01, 2038) • nobelz chemii dolarów) nagrody otrzymal chemik amerykanski K. barry sharpless. http://www1.gazeta.pl/nauka/1,34141,469977.html

Aukcje Dom Film Muzyka ... Gazeta Wyborcza poczta czat forum cafe katalog Szukasz przyjació³? Wst±p do CafeGazeta! on error resume next FlashMode = (IsObject(CreateObject("ShockwaveFlash.ShockwaveFlash.4"))) Sub TXHWCSJHJYFCFHKTBAIQUPZYOMWAOKM_FSCommand(ByVal command, ByVal args) call TXHWCSJHJYFCFHKTBAIQUPZYOMWAOKM_DoFSCommand(command, args) end sub Usenet - dyskusje na ka¿dy temat... Gazeta Wyborcza: Kraj ... Zdrowie Raporty Katastrofa Columbii Kasparow kontra Deep Junior Najwa¿niejsze odkrycia naukowe roku 2002 wed³ug "Science" Kongres neurobiologiczny w Orlando ... Chemia - ABC Niedziela , 20 kwietnia 2003 Nobel. Chemia. 2001 ZOBACZ TAK¯E Nobel. Chemia Sylwetki noblistów z chemii Thalidomid: historia szkodliwego leku Nagrodê Nobla z chemii komentuje prof. Janusz Jurczak z Wydzia³u Chemii Uniwersytetu Warszawskiego i Instytutu Chemii Organicznej Polskiej Akademii Nauk ... Nobel z chemii 2002 - za badanie bia³ek Marcin Jamkowski 10-10-2001, ostatnia aktualizacja 19-08-2002 17:52 Badania tegorocznych noblistów nad reakcjami utleniania i uwodorniania przy u¿yciu zwi±zków optycznie czynnych znalaz³y zastosowanie przy produkcji licznych antybiotyków, leków przeciwzapalnych i nasercowych

49. This Week In NIKKEI BUSINESS with Professor K. barry sharpless. A 60 yearold sharpless is a Professor at theScripps Research Institute, and is also one of the nobel Prize Laureates in http://www.nikkeibp.com/business/business1.html

Professor Katsuki supported the American Nobel Prize Laureate in chemistry By Shigetaka Mayumi(October 22, 2001 issue) Nobel Prize in Chemistry for 2001 was awarded to Nagoya University Professor Noyori Ryoji for his work on chirally catalysed hydrogenation reactions. But in fact, there exists another Japanese scientist who cannot be forgotten for his contribution to the research of catalytic asymmetric synthesis. Kyushu University Professor Tsutomu Katsuki, aged 55, is the name of the scientist. Back in 1980, he co-authored a thesis with Professor K. Barry Sharpless. A 60 year-old Sharpless is a Professor at the Scripps Research Institute, and is also one of the Nobel Prize Laureates in Chemist for the year 2001 besides Noyori. When Katsuki flew to the U.S. to visit Sharpless back in September 1979, Sharpless was at the stage of searching for metals suitable for catalysed oxidation reaction. Sharpless ventured a hypothesis that metals possessing the characteristics of low catalysis were suitable for having asymmetric reaction. Based on this hypothesis, Katsuki discovered that titanium was the effective substance in December 1979, only three months after he went to the U.S. Katsuki has contributed to the research of Sharpless by discovering effective ways of stabilizing an element (ligand) when bonded to a metal atom. After being awarded a Nobel Prize in Chemstry, Noyori made a remark by emphasizing that the achievements of the Japanese scientists in the field of chemistry were not diminutive. It is obvious that Katsuki's presence endorses the comments made by the Nobel Prize Laureate Noyori.

50. Alphabetical Listing Name, nobel Prize Category, Year Awarded. Sabatier, Paul, Chemistry, 1912. Sharpe,William F. Economics, 1990. sharpless, K. barry, Chemistry, 2001. http://www.almaz.com/nobel/alpha/S.html

Name Nobel Prize Category Year Awarded Sabatier, Paul Chemistry Sachs, Nelly Literature ... Medicine

51. Savannah NOW: Local News - Three Share Nobel Prize In Chemistry For Key Process Recent nobel winners in chemistry. 2001 William S. Knowles and K. barry sharpless,United States, and Ryoji Noyori, Japan, for showing how to better control http://www.savannahnow.com/stories/101101/LOCnobelchem.shtml

Humidity: 20% Wind: N at 6 mph HOME home finder auto finder job finder ... coastal antiques Web posted Thursday, October 11, 2001 Three share Nobel Prize in chemistry for key process in making medicines By Malcolm Ritter The Associated Press Two Americans and a Japanese scientist won the Nobel Prize in chemistry Wednesday for discoveries now used to manufacture a wide variety of medicines, including antibiotics, heart drugs and a widely used treatment for Parkinson's disease. William S. Knowles of St. Louis and Ryoji Noyori of Nagoya University in Japan shared half of the $943,000 award. K. Barry Sharpless of the Scripps Research Institute in La Jolla, Calif., won the other half. They overcame a key problem in making drugs: The molecules of many substances used as drugs come in two forms that are mirror images of each other, just as the left hand mirrors the right. And only one of these forms is helpful, while the other is inactive or even harmful. The three men developed chemical catalysts to produce only the useful form of such molecules. The resulting batches of drug are more potent and lack the side effects that the other form of the molecule would cause. "Many of the medicines we use every day are safer and more effective because of this important chemistry research," said Nina McClelland, chair of the American Chemical Society board of directors.

52. Zientzia Eta Teknologiaren Ataria dute saria. Kimikako nobel saria K. barry sharpless, Ryoji Noyori etaWilliam S. Knowles kimikarientzat izan da. Erreakzio kimikoak http://www.zientzia.net/artikulua.asp?Artik_kod=4015

53. Nobel-sivut The nobel Foundation Chemistry 2001 William S. Knowles St Louis, Missouri, USARyoji Noyori, Nagoya University, Chikusa, Nagoya, Japani K. barry sharpless, http://www.student.oulu.fi/~mirjak/nobel.html

Kemian Nobel-palkinnot Nobelstiftelsen, The Nobel Foundation Luettelo kemian nobelisteista (englanniksi ja saksaksi) The Nobel Prize Internet Archive Kemian Nobel 2002 The Nobel Foundation: Chemistry 2002 John B. Fenn , Virginia Commonwealth University, Richmond, USA Koichi Tanaka , Shimadzu Corp., Kioto, Japani Fenn ja Tanaka Kemian Nobel 2001 The Nobel Foundation: Chemistry 2001 William S. Knowles St Louis, Missouri, USA Ryoji Noyori , Nagoya University, Chikusa, Nagoya, Japani K. Barry Sharpless , The Scripps Research Institute, La Jolla, Kalifornia, USA William S. Knowles Ryoji Noyori K. Barry Sharpless Kemian Nobel 2000 The Nobel Foundation: Chemistry 2000 Alan J. Heeger , University of California, Santa Barbara, USA Alan G MacDiarmid , University of Pennsylvania, USA Hideki Shirakawa , University of Tsukuba, Japani Kemian Nobel 1999 femtokemian tutkimuksesta The Nobel Foundation: Chemistry 1999 Ahmed H. Zewail , California Institute of Technology, Pasadena, USA Egyptin kansalainen sekuntia eli desimaalilukuna ilmaisten 0,000000000000001 sekuntia. Kemian Nobel 1998 kvanttikemian tutkimuksesta The Nobel Foundation: Chemistry 1998 Walter Kohn , University of California, Santa Barbara, USA John A. Pople

54. 2001 Nobel Prizes Awarded Scripps Research Institute K. barry sharpless Awarded 2001 nobelPrize in Chemistry. nobel Web Site. Return to the AIRI Home Page. http://www.airi.org/member-news/mem-news-nobel-gen.htm

"A nationwide association of independent, not-for-profit research institutes conducting peer-reviewed basic and applied research in the biomedical and behavioral sciences." Home General Jobs Meetings ... Nobel Prizes Nobel Prizes Awarded Salk Institute Professor Sydney Brenner Receives 2002 Nobel Prize for Medicine Fred Hutchinson Cancer Research Center Lee Hartwell Awarded 2001 Nobel Prize in Physiology or Medicine Scripps Research Institute K. Barry Sharpless Awarded 2001 Nobel Prize in Chemistry Nobel Web Site Return to the AIRI Home Page For questions regarding this web site or AIRI, please contact David Issing at the AIRI Management Office at hq@airi.org

55. Direct AnaLyse Translate this page L'Académie Royale des Sciences de Suède a décidé d'attribuer le Prix nobel deChimie de l'année 2001 pour le K. barry sharpless The Scripps Research http://www.directanalyse.com/nobel.htm

UNE COLLABORATION : Communiqué de presse Le Prix Nobel de Chimie 2001 10 octobre 2001 L'Académie Royale des Sciences de Suède a décidé d'attribuer le Prix Nobel de Chimie de l'année 2001 pour le développement de la synthèse asymétrique catalytique, pour moitié collectivement à : William S. Knowles Saint-Louis, Missouri, USA, et à Ryoji Noyori Nagoya University, Chikusa, Nagoya, Japon, "pour leurs travaux sur les réactions d'hydrogénation catalysées par chiralité", et pour l'autre moitié à : K. Barry Sharpless The Scripps Research Institue, La Jolla, Californie, USA, "pour ses travaux sur les réactions d'oxydation catalysées par chiralité". La catalyse inverse optique Un grand nombre de molécules existent sous deux formes inverses optiques – comme le sont nos mains. Elles sont dites chirales. Les chercheurs ont constaté que, dans la nature, l'une des deux formes est souvent plus fréquente que l'autre. Dans nos cellules, l'une des formes inverses optiques "va comme un gant" à l'opposé de l'autre qui peut même s'avérer nocive. Les produits pharmaceutiques sont souvent composés de molécules chirales et la différenciation des deux formes peut se révéler vitale – ce que prouva la catastrophe provoquée par le Neurosedyn dans les années 60. Il est donc important de pouvoir produire les deux formes chirales séparément.

56. Editando K. Barry Sharpless Translate this page K. barry sharpless nació en Recibió el Premio nobel/Química nobel de Químicaen 2001, por haber logrado catalizar moléculas quirales mediante http://enciclopedia.us.es/wiki.phtml?title=K. Barry Sharpless&action=edit

57. Nobel E-Museum 2001 William S. Knowles, Ryoji Noyori, K. barry sharpless. Find a Laureate. Searchthis site. Marie Curie was the first to receive a nobel Prize twice. http://nobel.sdsc.edu/

2002 - Raymond Davis Jr., Masatoshi Koshiba, Riccardo Giacconi 2001 - Eric A. Cornell, Wolfgang Ketterle, Carl E. Wieman 2000 - Zhores I. Alferov, Herbert Kroemer, Jack S. Kilby 1999 - Gerardus 't Hooft, Martinus J.G. Veltman ... 1998 - John Hume, David Trimble Find a Laureate Search this site On November 27, 1895, Alfred Nobel signed his last will in Paris, briefly outlining his vision of five prizes for those who during the past year have done humanity the greatest service. The Will - Slide Show Laser Challenge The Transistor Chirality - Chemistry 2001 ... Tell us what you think about this site! Last modified April 18, 2003 The Official Web Site of The Nobel Foundation

58. Compass2001_08 Swedish Academy of Sciences has decided to award the nobel Prize in catalysed hydrogenationreactions and the other half to K. barry sharpless, the Scripps http://www.chem.csiro.au/library/Archive/compass2001_08.html

about the library search our web site newsletter Current Archive information sheets journals online ... search engines COMPASS "Pointing you in the right direction" No. 8/01 17th October, 2001 IN THIS ISSUE 2001 NOBEL PRIZE IN CHEMISTRY AND, TO BALANCE THE LEDGER NEW ELECTRONIC JOURNAL Russian journal of general chemistry TIPS AND TECHNIQUES Material safety data sheets FOR THE SURFBORED NICNAS National dangerous goods framework Biological and Chemical Weapons MEDLINEplus NEW ADDITIONS TO THE LIBRARIES 2001 NOBEL PRIZE IN CHEMISTRY P ress Release 10 October 2001 The Royal Swedish Academy of Sciences has decided to award the Nobel Prize in Chemistry for 2001 for the development of catalytic asymmetric synthesis, with one half jointly to William S. Knowles, St Louis, Missouri, USA, and Ryoji Noyori, Nagoya University, Chikusa, Nagoya, Japan, "for their work on chirally catalysed hydrogenation reactions" and the other half to K. Barry Sharpless, the Scripps Research Institute, La Jolla, California, USA, "for his work on chirally catalysed oxidation reactions". Mirror Image Catalysis William S. Knowles discovered that it was possible to use transition metals to make chiral catalysts for an important type of reaction called hydrogenation, thereby obtaining the desired mirror image form as the final product. His research quickly led to an industrial process for the production of the L-DOPA drug which is used in the treatment of Parkinson's disease. Ryoji Noyori has led the further development of this process to today's general chiral catalysts for hydrogenation.

59. CIENCIA EN EL MUNDO - PREMIO NOBEL DE QUIMICA 2001 Translate this page Dos norteamericanos y un japonés compartieron ayer el Premio nobel de Química pordemostrar cómo controlar La otra mitad fue para K. barry sharpless, de 60 http://www.asovac.org.ve/av_250_cienmundo_001.htm

CIENCIA EN EL MUNDO - PREMIO NOBEL DE QUIMICA 2001 El Nacional Jueves 11 de octubre del 2001 William S. Knowles Ryoji Noyori K. Barry Sharpless ESTOCOLMO/AP

60. Chemistry Nobel 2001 - For Printer This year's nobel Prize in Chemistry has been awarded to three researchers who developedthe technique of Half of the prize goes to K. barry sharpless of the http://www.nature.com/nsu/nsu_pf/011011/011011-17.html

Chemistry Nobel 2001 Nobel chemistry award has pleasing symmetry 11 October 2001 DAVID ADAM Ryoji Noyori of Nagoya University, Japan This year's Nobel Prize in Chemistry has been awarded to three researchers who developed the technique of catalytic asymmetric synthesis, which allows chemists to steer reactions towards one of two possible symmetrical products. Half of the prize goes to K. Barry Sharpless of the Scripps Research Institute in La Jolla, California, for his work on oxidation reactions. The other half is shared by two researchers for their work on hydrogenation reactions: Ryoji Noyori of Nagoya University, Japan, and William Knowles, a retired chemist who worked at biotechnology company Monsanto in St Louis, Missouri until 1986. The winners studied reactions that, under normal circumstances, produce an equal mixture of two products with symmetrical structures. Known as chiral products, these molecules are mirror images of each other, but can have very different properties. The side-effects of the morning-sickness drug thalidomide, for example, were caused by a rogue chiral twin of the molecule that the drug's designers had intended to use. Sharpless, Noyori and Knowles have been awarded the prize for developing techniques that tailor reactions so that only one of the two chiral molecules is produced. The techniques are now widely used in industry, particularly to manufacture pure pharmaceuticals.

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