Geometry.Net - Health_Conditions: Basal Ganglia Diseases

Neurobiological Lab - Neurodegenerative Diseases - University Rostock
Neurodegenerative Diseases. Pathophysiological and molecular genetic bases oftherapeutic effects of external neuromodulation in basal ganglia diseases.
http://neurobiology.med.uni-rostock.de/junior_research_group/neurodegenerative_d

Extractions: external neuromodulation in basal ganglia diseases Deep brain stimulation of basal ganglia is a successful means of therapeutic intervention for instance in Parkinson's disease. However, little is known about the mechanism on the molecular and cellular levels. Therefore an animal model for Parkinson's disease and a brain slice culture for modeling deep brain stimulation will be established in our lab. Effects on GABAergic, dopaminergic and c-fos mediated information pathways and ubiquitin-mediated protein degradation pathways will be characterized by molecular biological and neurophysiological analyses . For the latter in brief: changes in electrophysiological properties of high frequency stimulated compared to unstimulated neurons and networks for the acute and chronic situation will be studied. The influence of deep brain stimulation on the glial enviroment, especially on microglia and astrocytes , is in focus of the project.
Macomb Senior High
A description of basal ganglia followed by a look at some of the diseases such as sydenhams chorea, huntingtons chorea, cerebral palsy, athetosis, hemiballism and parkinsons disease.
http://www.macomb.com/~mhs/basal.htm
Jerrold D. Prothero
Anatomy; Motor Control Overview; The basal ganglia; basal ganglia Componentsand Pathways; diseases of the basal ganglia; basal ganglia
http://www.hitl.washington.edu/publications/prothero/home.html
DIRECTORY.TERADEX.COM - Health/Fitness/Diseases/Neurological Disorders/Brain Dis
Health/Fitness / diseases / Neurological Disorders / Brain diseases / basal ganglia (20). basal ganglia Hemorrhage
http://directory.teradex.com/Health_Fitness/Diseases/Neurological_Disorders/Brai

Extractions: Search through: Entire site Basal Ganglia Hallervorden-Spatz Syndrome Neuroleptic Malignant Syndrome Meige Syndrome DIRECTORY ... Basal Ganglia Hemorrhage Secondary to Lightning Stroke - A case history of an 18 year old male. Presents clinical history, radiological diagnosis and a discussion. Macomb Senior High - A description of basal ganglia followed by a look at some of the diseases such as sydenhams chorea, huntingtons chorea, cerebral palsy, athetosis, hemiballism and parkinsons disease. - A brief report from 1999. University of Manitoba - An article about the basal ganglia. University of Michigan - A very brief discussion about basal ganglia.
Basal Ganglia And Grating Therapies In Neurodegenerative Diseases
English title. basal ganglia and grating therapies in neurodegenerative diseases. Swedish title
http://research.kib.ki.se/e-uven/public/C41075.html

Extractions: English title Basal Ganglia and grating therapies in neurodegenerative diseases Swedish title Basala ganglierna och transplantationsterapier vid neurodegenerativ sjukdom Project leader Ingrid Strömberg All projects by this author Institution Department of Neuroscience All projects at this institution Section/unit Division of Development, Growth Factors and Transplantation All projects at this section/unit Description Main
1Up Health > Health Links Directory > Conditions And Diseases: Neurological Diso
Macomb Senior High A description of basal ganglia followed by a look at some of thediseases such as sydenhams chorea, huntingtons chorea, cerebral palsy
http://www.1uphealth.com/links/brain-diseases-basal-ganglia.html
1Up Health > Basal Ganglia Dysfunction > Causes, Incidence, And Risk Factors Of
1Up Health diseases Conditions basal ganglia dysfunction Causes, Incidence, and Risk Factors.
http://www.1uphealth.com/health/basal_ganglia_dysfunction_info.html

Extractions: 1Up Health Basal ganglia dysfunction Alternative Medicine Clinical Trials ... Health Topics A-Z Search 1Up Health Basal ganglia dysfunction Information Basal ganglia dysfunction Causes, Incidence, and Risk Factors Definition : Basal ganglia dysfunction involves dysfunction of the basal ganglia, a brain region involved in motor control and movement. Numerous brain disorders can cause basal ganglia dysfunction, including Parkinson's disease Huntington's disease progressive supranuclear palsy , corticobasal degeneration, multiple system atrophy Wilson disease , and dystonia In addition, any insult to the brain can potentially damage the basal ganglia including strokes, metabolic abnormalities, liver disease, multiple sclerosis , infections, tumors, drug overdoses or side effects, and head trauma. When the basal ganglia are damaged, control over functions such as speech and movement can be impaired. Difficulties with initiating movement, sustaining movement and stopping movement are all possible when this area is injured.
Motor Control 3: Cerebellum, Basal Ganglia And Movement Disorders
diseases of the basal ganglia produce a variety of motor symptoms tremor,athetosis, chorea, ballism, dystonia, akinesia, bradykinesia, rigidity.
http://www.anatomy.unimelb.edu.au/subjects/976/lectures/Cerbg.htm

Extractions: Part I: Basal Ganglia 1. The five components of the basal ganglia. All of these nuclei exept the substantia nigra, are regions of sub-cortical gey matter of the forebrain (telencephalon). The substantia nigra is part of the brainstem - midbrain. See figure 42-1 in the textbook (3rd ed) for anatomical locations. Note that there are various ways to group these nuclei: the caudate and putamen are collectivley the "striatum", the putamen and globus poalidus are refered to as the "lentiform nuclei".
Korean Standard Classification Of Diseases
G23 Other degenerative diseases of basal ganglia Exclusion multisystemdegeneration(G90.3) G23.0 Hallervorden-Spatz disease Pigmentary pallidal
http://www.nso.go.kr/eng/standards/edis/g23.htm

Extractions: G23 Other degenerative diseases of basal ganglia Exclusion £ºmulti-system degeneration(G90.3) G23.0 Hallervorden-Spatz disease Pigmentary pallidal degeneration G23.1 Progressive supranuclear ophthalmoplegia [Steele-Richardson- Olszewski] G23.2 Striatonigral degeneration G23.8 Other specified degenerative diseases of basal ganglia Calcification of basal ganglia G23.9 Degenerative disease of basal ganglia, unspecified
Conditions And Diseases: Neurological Disorders: Brain Diseases: Basal Ganglia:
Information on Conditions and diseases, Neurological Disorders, Brain diseases,basal ganglia, Meige Syndrome and much more Treasure Coast Health.
http://treasurecoasthealth.com/treasurecoasthealth.php/Health/Conditions_and_Dis

Extractions: Find Doctors on the Treasure Coast Select Specialty Ambulatory Care Anesthesiology Cardiology Dermatology Emergency Medicine Endocrinology Family Practice Gastroenterology Hematology/Oncology Infectious Diseases Internal Medicine Maxillofacial Surgery Neonatology Nephroology Neurology Neurosurgery Obstetrics/Gynecology Ophthalmology Orthopedic Surgery Otolaryngology Pathology Pediatics Physical Medicine Plastic Surgery Podiatry Psychiatry Psychology Pulmonary Radiation Oncology Radiology Rheumatology Surgery Thoracic Surgery Urology Vascular Surgery Select City Sebastian Palm Bay Vero Beach Fort Pierce Okeechobee Port St. Lucie Jensen Beach Stuart Palm City Hobe Sound Loxahatchee MENU Home Doctor Directory Health Resources Women Only ... About Us See also: Health: Conditions and Diseases: Rare Disorders http://www.nutrisystem.com We have helped millions of people lose weight for more than 30 years. Lose up to 10 lbs. in your first month! Blepharospasm, Meige Syndrome and Hemifacial Spasm
Conditions And Diseases Neurological Disorders Brain Diseases
Information on Conditions and diseases, Neurological Disorders, Brain diseases,basal ganglia, HallervordenSpatz Syndrome and much more Treasure Coast
http://treasurecoasthealth.com/treasurecoasthealth.php/Health/Conditions_and_Dis
Notes On The Basal Ganglia
substantia nigra pars reticulata to the superior colliculus and reticularformation. III. diseases of the basal ganglia 1. Parkinson's Disease
http://www2.umdnj.edu/~paneuweb/basgang.htm

Extractions: Maintained by David P. Crockett . E-mail suggestions to crockett@umdnj.edu (revised 3/11/97 Department of Neuroscience and Cell Biology UMDNJ-Robert Wood Johnson Medical School Room R-306, Telephone: 1-718-235-3404 PA Neuroscience Home Page 1. Diseases produce three characteristic types of motor disturbances: (1) involuntary movements, including tremor (particularly resting tremor); (2) poverty or slowness of movement without paralysis; and (3) changes in posture and muscle tone. 2. Terminology: The terminology is very confusing and has changed with time. It is now used to designate those structures which when damaged produce "extrapyramidal syndrome" (This too is a confusing term). Today the list includes: caudate nucleus, putamen, globus pallidus, subthalamic nucleus, and substantia nigra. a. Lenticular (lentiform) nucleus = putamen + globus pallidus (pallidum) b. Striatum (neostriatum) = caudate nucleus + putamen (common embryology and similar connections and identical histology, a functional term; anterior part of putamen fuses with the head of the caudate above the orbital surface of the frontal lobe) c. Corpus striatum = caudate nucleus + putamen + globus pallidus
CNS Pathology Index
basal ganglia hemorrhage with hypertension, gross CT; basal ganglia hemorrhagewith hypertension, gross CT; Acquired and Congenital Degenerative diseases.
http://medlib.med.utah.edu/WebPath/CNSHTML/CNSIDX.html

Extractions: The following images are present: Germinal matrix hemorrhage with intraventricular hemorrhage in 28 week gestational age newborn, gross Basal ganglia hemorrhage with hypertension, gross [CT] Basal ganglia hemorrhage with hypertension, gross [CT] Epidural hematoma, gross [CT] ... Cerebrum, coronal section, white matter petechiae with fat embolism syndrome, gross Pons, lacunar infarct, gross Lacunar infarct, microscopic Cerebrum, coronal section, acute cerebral infarct, gross Cerebrum, coronal section, acute watershed infarct, gross ... Cerebrum, brain stem, Wallerian degeneration, high power microscopic Cerebrum, coronal section, edema, gross Cerebrum, external view, edema, gross Cerebrum, uncal herniation from edema, gross Cerebrum, uncal herniation from edema, gross ... Pons, Duret hemorrhages, gross Cerebrum, external view, vertex, acute bacterial meningitis, gross Cerebrum, external view, vertex, acute bacterial meningitis, gross Cerebrum, external view, vertex, acute bacterial meningitis, gross Cerebrum, acute bacterial meningitis, gross ... Cerebrum, coronal section, hydrocephalus, gross Anencephaly, gross
Syllabus Chapter 12
Discussion of these basal ganglia includes reference to the subthalamic nucleus Nonetheless,a group of neurologic diseases are called extrapyramidal diseases
http://medlib.med.utah.edu/kw/hyperbrain/syllabus/syllabus12.html

Extractions: The objectives of this chapter are to: Understand the relationship of the basal ganglia to the cerebral cortex. Study the connections through which the basal ganglia affect motor function. The subcortical nuclei of the telencephalon are known collectively as the basal ganglia ( fig 12a The three basal ganglia that are studied in this chapter are the caudate ( ), putamen ( ), and globus pallidus ( Discussion of these basal ganglia includes reference to the subthalamic nucleus (nucleus of Luys) ( ) and the substantia nigra. ( All of these structures are included in the extrapyramidal motor system . The problem with this term is that it is ill-defined. Nonetheless, a group of neurologic diseases are called extrapyramidal diseases, including Parkinson's disease and Huntington's disease . One of their characteristic features is the presence of involuntary movements, for example, tremor and writhing movements. These abnormal movements are referred to as dyskinesias. Although there are attempts to develop a coherent explanation of the structure and function of the basal ganglia and their connections, these nuclear masses are still treated largely in an anecdotal fashion. Current ideas about the basal ganglia are based largely on neuropathologic case studies.
Basal Ganglia Disorders
nigrostriatal degeneration, dementing diseases such as Alzheimers and Picks;Multiple or bilateral strokes affecting basal ganglia; Toxicmetabolic
http://www.ucs.louisiana.edu/~ncr3025/roussel/codi555/basalganglia.html

Extractions: Basal Ganglia Control Circuits Globus pallidus is site or origin for major efferent (output) from basal ganglia Basal Ganglia Pathways Efferent pathways - major pathway is from globus pallidus to ventrolateral nucleus of the thalamus and then back to cortex Functions of the Basal Ganglia Control Circuits Effects of Lesions within Basal Ganglia Circuits Hypokinesia - reduced mobility Increase in muscle tone Resistence to movement Movements are slow, stiff and difficult to initiate or stop
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confronted with an MRI pattern of bilateral basal ganglia lesions, the differentialdiagnosis includes hypoxic injury, mitochondrial diseases, toxin exposure
http://www.medscape.com/viewarticle/434346_2
Untitled
production because the symptoms of Gulf War syndrome strongly resemble early symptomsof wellstudied degenerative diseases of the basal ganglia like Huntington
http://www.swmed.edu/home_pages/epidemi/gws/dopamine.htm

Extractions: Media Contact: Mindy Baxter melinda.baxter@email.swmed.edu BRAIN CELL DAMAGE UNDERLYING GULF WAR SYNDROME CAUSES ABNORMAL BRAIN DOPAMINE PRODUCTION, STUDY SHOWS DALLAS Sept. 14, 2000 In a study released today, researchers say they have found a strong link between brain cell loss on the left side of the brain in sick Gulf War veterans and abnormal over-production of dopamine, a neurotransmitter chemical important in such conditions as degenerative brain diseases. The UT Southwestern Medical Center at Dallas study, published in the American Medical Associations Archives of Neurology , links brain cell loss in the left basal ganglia of sick Gulf War veterans with out-of-control production of a brain neurotransmitter chemical called dopamine. With fewer total brain cells, the remaining dopamine-producing cells become over-responsive and produce too much dopamine. This finding gives increased importance to our earlier brain scan evidence of brain damage in these veterans," said Dr. Robert Haley, professor of internal medicine and holder of the U.S. Armed Forces Veterans Distinguished Chair for Medical Research, Honoring Americas Gulf War Veterans. Showing that the degree of brain cell injury directly affects the level of brain dopamine production indicates that the brain damage is having a real effect on these veterans brain function and is not just a coincidental finding. In the June issue of Radiology , UT Southwestern researchers reported that sick Gulf War veterans had 9 percent fewer brain cells in the left basal ganglia than healthy veterans. Previous research has shown that brain damage in the left basal ganglia causes a dramatic increase in dopamine production, while brain damage in the right basal ganglia has less effect.
Basal Ganglia Physiology, Pharmacology And Pathophysiology
pharmacology, physiology and pathophysiology of basal ganglia and movement disordersusing PET, MRI and in vitro measurements. The diseases studied include
http://research.medicine.wustl.edu/ocfr/Research.nsf/Abstracts/845B21B1B58968588
Paroxysmal Neuro Dysfunction/ Basal Ganglia
diseases of the basal ganglia give certain types of movement disorderssuch as dystonia, choreathetosis, chorea, etc. diseases such
http://www.medhelp.org/forums/neuro/messages/30351a.html

Extractions: Basal ganglia are responsible for control of motor movements, they act in concert with the cortex to smooth out movements. Diseases of the basal ganglia give certain types of movement disorders such as dystonia, choreathetosis, chorea, etc. Diseases such as mitochondrial cytopathies, Wilson's, Hunington's, essential tremor, Parkinson's etc have all been related to having a connection with the basal ganglia. Many mitochondrial disorders effect the basal ganglia, but not all. Even the same type of mitochondrial disease (i.e. MELAS) may or may not affect the basal ganglia.
TWO DISEASES, ONE HOPE
This surgical procedure is just as complicated as the diseases themselves. Thebiopsy entails taking precursors of adult basal ganglia cells from fetuses
http://serendip.brynmawr.edu/bb/neuro/neuro98/202s98-paper3/Sangaramoothy3.html

Extractions: the Treatment of Parkinson's and Huntington's Disease Parkinson's Disease (PD) and Huntington's Disease (HD) are neurodegenerative diseases that are caused by malfunctions within the motor sector of the nervous system. These malfunctions, which are caused either by the surplus (as in HD) or absence (as in PD) of hormones, are a direct result of neural cell deterioration within the brain. PD and HD illustrate two very different behavioral patterns that are subsequently caused by two opposite and extreme biological abnormalities. Yet the common thread between the two conditions is that there are major mechanical predicaments arising between cellular connections within the brain. Thus, it is the occurrence of cell death that functions as a key link between these two very different diseases. And it is because of this commonality, that the most controversial experimental treatment for PD and HD, fetal transplant surgery, functions as a possible cure for both these diseases. ( ). The cause of neurodegenerative diseases, like PD and HD, is basically a story of how abnormal chemical interactions result in motor problems. Generally speaking, the brain is the body's communication headquarters. It obtains a myriad of information from various parts of the sensory system and processes this information in an organized fashion. It then relays sensory input to different parts of the motor system. Such messages from the brain dictate specific muscular and behavioral patterns. (

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