Geometry.Net - Health_Conditions: Pemphigus

Virtual Hospital: An Introduction To Basic Dermatology: Pemphigus
An Introduction to Basic Dermatology. pemphigus. Two of the more important categoriesof large blister diseases are pemphigus and bullous pemphigoid.
http://www.vh.org/adult/provider/dermatology/PietteDermatology/BlackTray/41Pemph

Extractions: Peer Review Status: Internally Peer Reviewed Two of the more important categories of large blister diseases are pemphigus and bullous pemphigoid. Pemphigus involves blistering because of separation between cells within the epidermis, while bullous pemphigoid involves separation of the full thickness of epidermis from the basement membrane. Because of the more superficial location of the epidermal separation in pemphigus, the blisters or bullae in pemphigus tend to be much more fragile than those seen in bullous pemphigoid. The lesions shown are those of pemphigus vulgaris. Next Page Title Page See related Provider Textbooks about Dermatology See related Provider Topics Dermatology Skin DiseasesGeneral or Skin, Hair and Nails See related Patient Textbooks about Dermatology See related Patient Topics Dermatology Skin DiseasesGeneral or Skin, Hair and Nails Virtual Hospital Home Virtual Children's Hospital Home Site Map ... UI Health Care Home http://www.vh.org/adult/provider/dermatology/PietteDermatology/BlackTray/41Pemphigus.html
Pemphigus Research At Johns Hopkins Medicine
DEPARTMENT OF DERMATOLOGY. pemphigus RESEARCH. pemphigus Research at Johns HopkinsMedicine. The Johns Hopkins Laboratory For Translational Research in pemphigus.
http://www.hopkinsmedicine.org/pemphigus/

Extractions: Johns Hopkins Medicine HISTORY Although our understanding of autoimmune diseases has increased tremendously in the last decade, pemphigus remains a devastating disease for those who are affected and their family members. Pemphigus affects adluts in their most productive years, the middle years of life. Fifty years ago, the diagnosis of pemphigus meant certain death. Currently, the chance of dying from the disease or the compliations of treatment is remote. However, the immunosuppressive therapy required to control the disease is oppressive. It changes one's life with devastating physical and psychological stresses and sets in place the potential for serious side effects, some of which might not become apparent for years or decades after treatment. RESEARCH PROGRAM The Department of Dermatology at Johns Hopkins has a long history of distinguished research in the field of autoimmunity and pemphigus. Dr. Anhalt and coworkers developed the first animal model for pemphigus and used this model to define the events that are critical to the development of blistering skin and mucous membranes in pemphigus. Their work has clarified that effective therapeutics for this disease must be directed at inhibition of autoantibody production, and their laboratory efforts are devoted to this goal.
Pemphigis
DEPARTMENT OF DERMATOLOGY. pemphigus RESEARCH. AT JOHNS HOPKINS MEDICINE.TYPES OF pemphigus. pemphigus VULGARIS. pemphigus FOLIACEUS. IgA pemphigus.
http://www.hopkinsmedicine.org/pemphigus/iga.shtml
Pemphigus
related terms pemphigus foliaceus, pemphigus erythematosus. What is pemphigus? Howis pemphigus inherited? unknown. What breeds are affected by pemphigus?
http://www.upei.ca/~cidd/Diseases/immune disorders/pemphigus.htm

Extractions: related terms: pemphigus foliaceus, pemphigus erythematosus What is pemphigus? Pemphigus covers a group of uncommon disorders that occur in dogs. With these conditions, there is an abnormal immune response to normal components of the skin, resulting in separation of cells. This leads to blisters, pustules, and crusting erosions in the skin. There are some similarities to pemphigus in humans, but many significant differences as well. Breed predispositions are recognized for 2 forms - pemphigus foliaceus and the milder pemphigus erythematosus. (There are no breed predispositions recognized for the other 2 forms - p. vulgaris and p. vegetans). How is pemphigus inherited? unknown What breeds are affected by pemphigus pemphigus foliaceus: bearded collie, akita, Doberman pinscher, Newfoundland, Schipperke pemphigus erythematosus: collie, German shepherd and German shepherd crosses For many breeds and many disorders, the studies to determine the mode of inheritance or the frequency in the breed have not been carried out, or are inconclusive. We have listed breeds for which there is a consensus among those investigating in this field and among veterinary practitioners, that the condition is significant in this breed. What does pemphigus Pemphigus foliaceus and erythematosus develop around 4 years of age. P. erythematosus is thought to be a milder form of p. foliaceus. Both conditions begin with pustular, crusty lesions on the face and ears. However with p. foliaceus, the lesions spread to the feet, the groin and other areas; there may be itching and pain; and severely affected dogs may lose their appetite and become depressed.
EMedicine - Pemphigus, IgA : Article By Lawrence Chan, MD
pemphigus, IgA Immunoglobulin A (IgA) pemphigus is a group of newly characterizedimmune-mediated intraepidermal blistering skin diseases.
http://www.emedicine.com/derm/topic315.htm

Extractions: (advertisement) Home Specialties CME PDA ... Patient Education Articles Images CME Patient Education Advanced Search Link to this site Back to: eMedicine Specialties Dermatology Bullous Diseases Last Updated: October 24, 2001 Rate this Article Email to a Colleague Synonyms and related keywords: intraepidermal neutrophilic IgA dermatosis, intercellular IgA vesiculopustular dermatosis, intercellular IgA dermatosis, intraepidermal IgA pustulosis, IgA pemphigus AUTHOR INFORMATION Section 1 of 11 Author Information Introduction Clinical Differentials ... Bibliography Author: Lawrence Chan, MD Lawrence Chan, MD, is a member of the following medical societies: Alpha Omega Alpha American Academy of Dermatology American Association of Immunologists , American Society for Investigative Pathology, Federation of American Society of Experimental Biology , and Society for Investigative Iennatology Editor(s): Takeji Nishikawa, MD , Chair, Professor, Department of Dermatology, Keio University, Japan; David F Butler, MD
EMedicine - Pemphigus Vulgaris : Article By Bassam Zeina, MD, PhD
pemphigus Vulgaris pemphigus is derived from the Greek word pemphixmeaning bubble or blister. pemphigus describes a group of
http://www.emedicine.com/derm/topic319.htm

Extractions: (advertisement) Home Specialties CME PDA ... Patient Education Articles Images CME Patient Education Advanced Search Link to this site Back to: eMedicine Specialties Dermatology Bullous Diseases Last Updated: November 30, 2001 Rate this Article Email to a Colleague AUTHOR INFORMATION Section 1 of 10 Author Information Introduction Clinical Differentials ... Bibliography Author: Bassam Zeina, MD, PhD , Consulting Staff, Department of Dermatology, Milton Keynes Hospital, UK Coauthor(s): Mohsin Ali, BSc, MBBS, MRCPI, MRCP , Consulting Staff, Department of Dermatology, Amersham General Hospital, UK Bassam Zeina, MD, PhD, is a member of the following medical societies: International Society of Dermatology Tropical, Geographic and Ecologic Editor(s): Abby Van Voorhees, MD , Director of Psoriasis Services and Phototherapy, Assistant Professor, Department of Dermatology, University of Pennsylvania Hospital; Richard Vinson, MD , Chief, Department of Dermatology, William Beaumont Medical Center; M Joyce Rico, MD
Page 29 Pemphigus Vulgaris
pemphigus Vulgaris. pemphigus membranes. pemphigus vulgaris begins withblister formations (bullae) occurring in the mouth and on the scalp.
http://www.aarda.org/page29a.html

Extractions: Pemphigus Vulgaris Pemphigus is a group of chronic autoimmune skin diseases characterized by blister formations in the outer layer of the skin and the mucous membranes. Pemphigus vulgaris begins with blister formations (bullae) occurring in the mouth and on the scalp. The blisters are soft and are easily broken. The blistering can also affect the esophagus, rectum, nose or the lining of the eyelids. These bullae heal without scarring. Pemphigus vulgaris predominately occurs in middle-aged patients of Jewish or Mediterranean descent. Pemphigus vulgaris has been associated with other autoimmune diseases, such as myasthenia gravis and systemic lupus. Diagnosis of an autoimmune bullous disease should be suspect when there is no clear history of exposure to a drug or a contact allergen or when other studies for infectious origins, such as herpes or impetigo, are negative. To differentiate these diseases, a careful history and physical examination are important. A skin biopsy is often helpful. For more information on Pemphigus Vulgaris or other autoimmune disorders, please click on the request information icon below.
Pemphigus
pemphigus. Back to previous level pemphigus, Benign Familial SearchPUBMED for pemphigus, Benign Familial All Review Therapy Diagnosis.
http://www.ohsu.edu/cliniweb/C20/C20.111.736.html
Untitled
pemphigus Vulgaris. Almost every patient with PV has oral manifestations, butonly 50% of patients with pemphigus vegetans present oral involvement.
http://www.dent.ucla.edu/pic/members/pemphigus/

Extractions: California Continuing Education Credits: 4 units PIC Homepage Member Homepage Page [ Intro Treatment References Basically all of the so-called bullous diseases of the skin present oral lesions. Some will manifest in the oral mucosa prior to the skin lesions and some others only after the dermatologic manifestations have taken place. Still another group will have mostly mucous membranes involvement with only minor skin changes. Pemphigus is a severe dermatologic disease that is generally divided into pemphigus vulgaris (PV), pemphigus vegetans, pemphigus foliaceous, pemphigus erythematosus and benign familial chronic pemphigus. Some drugs with terminal sulfhydryl groups (i.e. penicillamine) can induce lesions which are clinically identical to those seen in PV. Malignant neoplasms are also capable of producing the so-called paraneoplastic PV which is similar to the classic PV.
Pemphigus
pemphigus FOLIACEUS. INDEX pemphigus research samples Symptoms. In pemphigus,the autoimmune system is directed against the skin itself.
http://www.akitaclub.org/web/health/pemphigus.html

Extractions: Home Up Bloat Cancer ... Canine Longevity Study [ Pemphigus ] PRA in Akitas SA in Akitas VKH in Akitas PEMPHIGUS FOLIACEUS INDEX: pemphigus research samples Symptoms In pemphigus, the autoimmune system is directed against the skin itself. Affected dogs have what looks like a rash at onset that develops into blisters and then pustules. Finally, the dog is left with crusty sores on the non-furred areas of skinthe pads, nose, lips, and eye rims. Occasionally, all the skin is involved, but this is less common. Because the produce pigment-production cells in the skin may be affected also, color may disappear from involved areas. Affected dogs are usually maintained on steroids with the dosage being adjusted with the severity of symptoms. If steroids alone are not effective, then other immunosuppressors can be used. Treated dogs can often live a fairly normal life, but the disease cannot be cured. Affected dogs should certainly not be bred.
Drug-Induced Pemphigus
DrugInduced pemphigus Drug-Triggered pemphigus. Mechanism of Drug-Induced pemphigusSulfhydryl groups lyse disulfide bonds; Results in Blister formation.
http://www.fpnotebook.com/DER182.htm

Extractions: Home About Links Index ... Editor's Choice Paid Advertisement (click above). Please see the privacy statement Dermatology Pharmacology Acne ... Blister Drug-Induced Pemphigus Dry Wet Dressings Skin Lubricant Alpha-Hydroxy acid ... Podophyllin Assorted Pages Topical Dermatologic Preparations Preparation Bases Topical Corticosteroids Oatmeal Bath ... Soaps Drug-Induced Pemphigus Drug-Triggered Pemphigus Book Home Page Cardiovascular Medicine Dental Dermatology Emergency Medicine Endocrinology Gastroenterology General Medicine Geriatric Medicine Gynecology Hematology and Oncology HIV Infectious Disease Jokes Laboratory Neonatology Nephrology Neurology Obstetrics Ophthalmology Orthopedics Otolaryngology Pediatrics Pharmacology Prevention Psychiatry Pulmonology Radiology Rheumatology Sports Medicine Surgery Urology Chapter Dermatology Index Acne Allergy Bacteria Blister Cardiovascular Medicine Dermatitis Dry Endocrinology Environmental Injury Examination Ophthalmology Fungus Hair Hematology and Oncology Hyperplasia Infectious Disease Laboratory General Nails Parasite Pediatrics Pharmacology Pigment Prevention Procedure Psychiatry Rheumatology Sebaceous Sports Medicine Sweat Symptom Evaluation Wart Page Pharmacology Index Acne Accutane Acne Antibiotic Azelaic Acid Acne Antibiotic Clindamycin Acne Antibiotic Erythromycin Acne Antibiotic Sulfur Acne Antibiotic Tetracycline Acne Comedolytic Acne Comedolytic Adapalene Acne Comedolytic Benzoyl Peroxide Acne Comedolytic Tretinoin Blister Pemphigus Dry Burrows Solution Dry Emollient Dry Emollient Additions Dry Emollient Bath
Pemphigus
pemphigus Intraepidermal Blister. Contrast with the deeper Pemphigoid. Types Primaryforms of pemphigus Deep pemphigus (above Basal Cell Layer of Epidermis)
http://www.fpnotebook.com/DER35.htm

Extractions: Home About Links Index ... Editor's Choice Paid Advertisement (click above). Please see the privacy statement Dermatology Blister Dermatitis ... Dermatitis Herpetiformis Assorted Pages Pemphigoid Bullous Pemphigoid Chronic Bullous Disease of Childhood Cicatricial Pemphigoid ... Drug-Induced Pemphigus Pemphigus Intraepidermal Blister Book Home Page Cardiovascular Medicine Dental Dermatology Emergency Medicine Endocrinology Gastroenterology General Medicine Geriatric Medicine Gynecology Hematology and Oncology HIV Infectious Disease Jokes Laboratory Neonatology Nephrology Neurology Obstetrics Ophthalmology Orthopedics Otolaryngology Pediatrics Pharmacology Prevention Psychiatry Pulmonology Radiology Rheumatology Sports Medicine Surgery Urology Chapter Dermatology Index Acne Allergy Bacteria Blister Cardiovascular Medicine Dermatitis Dry Endocrinology Environmental Injury Examination Ophthalmology Fungus Hair Hematology and Oncology Hyperplasia Infectious Disease Laboratory General Nails Parasite Pediatrics Pharmacology Pigment Prevention Procedure Psychiatry Rheumatology Sebaceous Sports Medicine Sweat Symptom Evaluation Wart Page Blister Index Dermatitis Herpetiformis Pemphigoid Pemphigoid Bullous Pemphigoid CBDC Pemphigoid Cicatrical Pemphigoid EBA Pemphigoid LAD Pemphigus Pemphigus Foliaceus Pemphigus Vegetans Pemphigus Vulgaris See Also Bullous Disease Pemphigoid Definition Intraepidermal Acantholytic Blister Mnemonic: Pemphigus ends in S for Superficial Contrast with the deeper Pemphigoid Types: Primary forms of Pemphigus Deep Pemphigus (above Basal Cell Layer of
Example Site - P Pemphigus
pemphigus pemphigus This disease is actually a group of diseases which act similarly. Pleasesee the individual pemphigus problems for further details.
http://www.totalskincare.com/library/totalskincare_p_pemphigus.html
Example Site - P Pemphigus Vulgaris
pemphigus Vulgaris pemphigus Vulgaris pemphigus Vulgaris is the most oftenseen of the pemphigus diseases, but fortunately is relatively unusual.
http://www.totalskincare.com/library/totalskincare_p_pemphigus-vulgaris.html

Extractions: Pemphigus Vulgaris is the most often seen of the pemphigus diseases, but fortunately is relatively unusual. It usually affects people of Mediterranean descent in their middle age. It often occurs at its outset as mouth erosions. Blisters in the mouth are often repetitively traumatized. Progression can occur to the skin on any area of the body, but the trunk and extremities are the areas most often involved. The treatment for this is injections of Kenalog either intramuscularly or intravenously. Oral prednisone can also play a role. The use of antibiotics is also important. Other drugs which cause a reduction in immune response have played a role such as Methotrexate or Cytoxan. Topical antibiotics also play a role.
Pemphigus
American Osteopathic College of Dermatology skin disease database pemphigus isa rare autoimmune blistering disorder of the skin.The immune system produces
http://www.aocd.org/skin/dermatologic_diseases/pemphigus.html

Extractions: Pemphigus is a rare autoimmune blistering disorder of the skin. The immune system produces protective antibodies that circulate through our blood and protect us from attack by hostile viruses and bacteria. In pemphigus however, the antibodies mistakenly consider normal tissues as foreign and attack them. This produces painful raw areas on the skin and mucous membranes (mouth and other moist linings) that will not heal. In some cases, these sores can cover a significant area of the skin. Before modern drug treatments, death from overwhelming infection was the usual outcome, but this is no longer common. Pemphigus has several types. Each type looks and acts differently. There are other autoimmune blistering diseases of the skin, such as bullous pemphigoid , bullous lupus, and Hailey-Hailey disease that can be confused with pemphigus. Because this is a complex condition to diagnose, special testing is needed. The three main categories of pemphigus are paraneoplastic pemphigus, pemphigus vulgaris and pemphigus foliaceus. This most serious form of pemphigus is paraneoplastic pemphigus. This occurs most often in someone who has already been diagnosed with an internal malignancy (cancer). Fortunately, it is also the most rare. Painful sores of the mouth, lips and esophagus are almost always present; and skin lesions of different types occur. This disease is usually not responsive to treatment. The diagnosis of this type should prompt doctors to search for a hidden tumor. In some cases the tumor will be benign and the disease will improve if the tumor is surgically removed.
Familial Benign Pemphigus
Familial benign pemphigus Thomas Casey Gallagher, MD Dermatology Online Journal6(1) 7. Department DIAGNOSIS Familial benign pemphigus. COMMENT
http://dermatology.cdlib.org/DOJvol6num1/NYUcases/hailey/Hailey.html

Extractions: PATIENT: 38-year-old man DURATION: Thirty-one years DISTRIBUTION: Lateral aspects of the neck and right axilla HISTORY: The lesions have recurred and remitted since childhood. He notes pruritus with a flare of his condition. Friction seems to exacerbate the eruption. There is a history of recurrent infections. Family history includes two siblings and a paternal uncle with the same condition. Figure 1 Figure 2 PHYSICAL EXAMINATION: Erythematous plaques with multiple, crusted erosions were noted in the right axilla and on the lateral aspects of the neck. There were no intact vesicles or bullae. LABORATORY DATA: . None HISTOPATHOLOGY: There is epidermal hyperplasia with areas of nearly full-thickness suprabasal acantholysis. DIAGNOSIS: Familial benign pemphigus COMMENT: Familial benign pemphigus, which is known as Hailey-Hailey disease, is an autosomal dominant condition that arises from a disorder in keratinocyte adhesion.[ ] Skin fragility is probably due to abnormalities in desmosomal components and keratin filament attachment to desmosomes.[
Pemphigus Foliaceous
pemphigus foliaceous Elizabeth K. Hale Dermatology Online Journal 8(2) 9. Localizedpemphigus foliaceous may often be treated adequately with topical therapy.
http://dermatology.cdlib.org/DOJvol8num2/NYUcases/3/3.html

Extractions: refs = new Array("References:","Ahmed AR, Salm M. Juvenile pemphigus. J Am Acad Dermatol 8:799, 1983", "Basset N, et al. Dapsone as initial treatment in superficial pemphigus: report of nine cases. Arch Dermatol 123:783, 1987 ", "Kanwar AJ, Kaur S. Pemphigus in children. Int J Dermatol 30:343, 1992 ", "Kanwar AJ, Dhar S. Further experience with pemphigus in children. Pediatr Dermatol 11:107, 1994 ", "Lin MS, et al. The desmosome and hemidesmosome in cutaneous autoimmunity. Clin Exper Immunol 107:9, 1997 "); DOJ From New York University Department of Dermatology This 12 year-old girl has had an eruption involving the scalp, trunk, and extremities for six years. The patient first presented to the Charles C. Harris Skin and Cancer Pavilion in March, 1995, with a generalized pruritic eruption of flaccid bullae and crusted erosions. She was otherwise healthy. A biopsy was performed at that time, and a diagnosis was made based on clinical, histopathologic, and immunofluorescence data. Treatment has consisted of prednisone, dapsone, and topical glucocorticoid preparations. Figure 1 Figure 2 Hyperkeratotic papules and plaques, in addition to several crusted erosions, were concentrated on her distal extremities. The eruption was less generalized than it was on initial presentation six years ago. There are no intact blisters at this time, and there were no lesions of the oral mucosa.
Roche Lexikon Medizin (4. Aufl.) - Pemphigus
Translate this page Pem phigus. engl. pemphigus. P. vulgaris. engl. p. vulgaris. pemphigus vulgaris393. (HEBRA, KAPOSI 1874) meist an Schleimhäuten (va Mund) beginnender u. evtl.
http://www.gesundheit.de/roche/ro27500/r29399.html
THE MERCK MANUAL, Sec. 10, Ch. 120, Bullous Diseases
Linear Immunoglobulin A Disease. click here for navigation help. pemphigus. pemphigususually occurs in middleaged or elderly persons and is rare in children.
http://www.merck.com/pubs/mmanual/section10/chapter120/120b.htm

Extractions: This Publication Is Searchable The Merck Manual of Diagnosis and Therapy Section 10. Dermatologic Disorders Chapter 120. Bullous Diseases Topics [General] Pemphigus Bullous Pemphigoid Dermatitis Herpetiformis ... Linear Immunoglobulin A Disease Pemphigus An uncommon, potentially fatal autoimmune skin disorder characterized by intraepidermal bullae and extensive erosions on apparently healthy skin and mucous membranes. Pemphigus usually occurs in middle-aged or elderly persons and is rare in children. Foci of high incidence occur in South America, especially Brazil. In active pemphigus, the serum and skin contain readily demonstrable IgG antibodies that bind at the site of epidermal damage. These antibodies can induce the same pathologic process in vivo and in vitro. Symptoms and Signs The primary lesions are flaccid bullae of various sizes, but often the skin or mucosae just shear off, leaving painful erosions. Lesions typically occur first in the mouth, where they rupture and remain as chronic, often painful, erosions for variable periods before the skin is affected. The bullae typically arise from healthy-appearing skin, rupture, and leave a raw area and crusting. Any area of stratified squamous epithelium may be affected, but the extent of skin and mucosal involvement varies (eg, lesions may occur in the oropharynx and upper esophagus). Itching is usually absent. In some superficial varieties (eg, pemphigus foliaceus), bullae may not be prominent and usually are absent from the mouth. The lesions may be localized to the face, and the large crusty scales may suggest a combination of seborrheic dermatitis and subacute cutaneous lupus erythematosus. Pemphigus foliaceus may resemble exfoliative dermatitis, psoriasis, a drug eruption, or other forms of dermatitis.
HONselect - Pemphigus, Benign Familial
English pemphigus, Benign Familial, Familial Benign Chronic pemphigus - Hailey-HaileyDisease - Benign Familial pemphigus - Familial pemphigus, Benign
http://www.hon.ch/HONselect/RareDiseases/C17.800.827.700.html

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

21-40 of 94 Back | 1 | 2 | 3 | 4 | 5 | Next 20