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Sickle Cell Disease:     more books (100)

Sickle-cell Disease Development and evaluation of a sickle cell disease assessment instrument.(Continuing Education Series): An article from: Pediatric Nursing by Sara W. Day, 2004-11-01 Medicine, culture, and sickle cell disease.(Dying in the City of the Blues: Sickle Cell Anemia and the Politics of Race and Health): An article from: The Hastings Center Report by Troy Duster, 2002-07-01 Hope and Destiny: The Patient and Parent's Guide to Sickle Cell Disease and Sickle Cell Trait by Allan F. Platt Jr. P.A.-C.M.M.Sc., Dr. James Eckman M.D., et all 2010-10-15 GUIDELINE FOR THE MANAGEMENT OF ACUTE AND CHRONIC PAIN IN SICKLE CELL DISEASE by anonymous, 1999 Sickle cell disease;: Its tragedy and its treatment by Jessyca Russell Gaver, 1972 Hydroxyurea therapy: improving the lives of patients with sickle cell disease.: An article from: Pediatric Nursing by Nina Anderson, 2006-11-01 Pain in Sickle Cell Disease (A Sickle Cell Society Publication) The management of sickle cell disease Gale Encyclopedia of Medicine: Sickle cell disease by CGC Jennifer Bojanowski MS, 2002-01-01 Cytrx announces reissue of key Flocor patent for treatment of sickle cell disease.(Brief Article): An article from: BIOTECH Patent News Management and therapy of sickle cell disease (NIH publication) The roentgenological features of sickle cell disease and related hemoglobinopathies by Jack Reynolds, 1965 Pathology of Sickle Cell Disease. by Joseph Song, 1971-06

lists with details

61. Sickle Cell Disease - English And Spanish Versions — Fanlight Productions
    hospitalization. This program examines the devastating impact of sickle celldisease on these young people and their families and caregivers. I  
    http://www.fanlight.com/catalog/films/906_scdesl.shtml
    
    Extractions: Use the shopping cart buttons at right to order both language versions of this film. To order either version individually, use the links below: Sickle Cell Disease: The Faces of Our Children (English) Anemia Falciforme: Los Rostros de Nuestros Niños (Dubbed in Spanish) Nearly 50 to 80,000 African-Americans (and a very much smaller number of whites) have sickle cell anemia, a genetic disease in which red blood cells become stiff, sticky and misshapen. In a "sickle cell crisis," which can occur for a variety of reasons, or for no apparent reason at all, the sickle-shaped cells can block blood vessels, causing severe pain in the chest, back, abdomen and joints. Repeated crises will eventually damage the kidneys, the heart and blood vessels, and other organs. One in ten children with sickle cell disease will have a stroke before they are fifteen; another ten percent have "silent" strokes, which nonetheless impair their school abilities and other functioning. Despite advances in treatment, this is in danger of becoming a "forgotten disease," with government funding for research and public information declining to a trickle compared to a few years ago. This program examines the devastating impact of sickle cell disease on these young people and their families and caregivers. It will be an important tool for increasing awareness in the community and among healthcare and social service providers in community clinics, hospitals, and other settings.

62. Sickle Cell Disease — Fanlight Productions
    hospitalization. This program examines the devastating impact of sicklecell disease on these young people and their families and caregivers.  
    http://www.fanlight.com/catalog/films/305_scd.shtml
    
    Extractions: Nearly 50 to 80,000 African-Americans, and a very much smaller number of whites, have sickle cell anemia, a genetic disease in which red blood cells become stiff, sticky and misshapen. In a "sickle cell crisis," which can occur for a variety of reasons or for no apparent reason at all, the sickle-shaped cells can block blood vessels, causing severe pain in the chest, back, abdomen and joints. Repeated crises will eventually damage the kidneys, the heart and blood vessels, and other organs. One in ten children with sickle cell disease will have a stroke before they are fifteen; another ten percent have "silent" strokes, which nonetheless impair their school abilities and other functioning. Despite advances in treatment, this is in danger of becoming a "forgotten disease," with government funding for research and public information declining to a trickle compared to a few years ago. This program examines the devastating impact of sickle cell disease on these young people and their families and caregivers. It will be an important tool for increasing awareness in the community and among healthcare and social service providers in community clinics, hospitals, and other settings. Spanish language version available:

63. Sickle Cell Disorder
    Sickle Cell Disorder. sickle cell disease describes a group of inherited disordersof red blood cells. sickle cell disease affects more than 50,000 Americans.  
    http://gslc.genetics.utah.edu/units/newborn/infosheets/sicklecelldisorder.cfm
    
    Extractions: Home ... Full Medical Reports Sickle Cell Disorder Sickle cell disease describes a group of inherited disorders of red blood cells. Red blood cells are responsible for delivering oxygen to different parts of the body; normally they are round and contain a molecule called hemoglobin, which carries oxygen. If the gene encoding hemoglobin is mutated, it causes a change in the shape of the molecule. When the mutated hemoglobin delivers oxygen to the tissues, the red blood cell collapses, resulting in a long, flat sickle-shaped cell. These cells clog blood flow, resulting in a variety of symptoms including pain, increased infections, lung blockage, kidney damage, delayed growth and anemia (low blood cell count). The gene encoding the beta chain of the hemoglobin molecule, located on chromosome 11, can be mutated in a variety of ways that result in different types of sickle cell disease. Some mutations are more common than others. The three most common types of sickle cell disease in the United States are hemoglobin SS (Hb SS), hemoglobin SC (Hb SC), and hemoglobin sickle beta-thalassemia (HbS beta-thalassemia). Autosomal recessive.

64. Patterns Of Mortality In Sickle Cell Disease In Adults In France And England
    Patterns of mortality in sickle cell disease in adults in France and England. death;sickle cell disease; acute chest syndrome; vasoocclusion; pregnancy.  
    http://www.nature.com/cgi-taf/DynaPage.taf?file=/thj/journal/v3/n1/full/6200147a

65. Sickle Cell Anemia
    Complications of sickle cell disease may include pain, stroke, increasedrisk of infection, and leg ulcers. Signs of sickle cell  
    http://www.labtestsonline.org/understanding/conditions/sickle.html
    
    Extractions: TESTS test not listed? ACTH AFB Culture AFP Maternal AFP Tumor Marker Albumin Aldosterone Allergies ALP ALT Amylase ANA Antibody Tests Apo A Apo B ApoE Genotyping AST Bilirubin Blood Culture Blood Gases BMP BNP Bone Markers BRCA BUN C-peptide CA-125 CA 15-3 CA 19-9 Calcium Cardiac Risk CBC CEA CF Gene Mutation Chlamydia Chloride Cholesterol CK CK-MB CMP Cortisol Creatinine Creatinine Clearance CRP CRP, high-sensitivity Cystatin C DHEAS Differential EGFR Electrolytes ESR Estrogen Estrogen Receptors Fecal Occult Blood Ferritin Flu Tests FSH Genotypic Resistance GFR GGT Glucose Gonorrhea Gram Stain Growth Hormone hCG HDL Hematocrit Hemoglobin Hepatitis A Hepatitis B Hepatitis C Her-2/neu Herpes HIV Antibody Home Tests Homocysteine HPV H-pylori hs-CRP Insulin Iron Tests LD LDH LDL Lead LH Lipase Lipid Profile Liver Panel Lp(a) Lyme Disease Magnesium Microalbumin Mono Monoclonal Protein Myoglobin Pap Smear Phosphorus Platelets Potassium Prealbumin Progesterone Progest. Receptors Prolactin PSA PT PTH Red Count Renin Rheumatoid Factor Rubella Semen Analysis Serum Iron Sickle Cell Sodium Strep Throat Sweat Chloride Syphilis Tau/Aß42 TB Skin Test Testosterone Ther. Drug Monitoring

66. Gene Therapy Used To Treat Sickle Cell Disease In Mice
    Gene Therapy Used to Treat sickle cell disease in Mice About 72,000 in the UnitedStates have two copies of the sickle cell gene and have the disease.  
    http://news.nationalgeographic.com/news/2001/12/1213_TVsickle.html
    
    Extractions: Sickle cell disease, which can be fatal, is caused by a genetic mutation in the hemoglobin gene that causes red blood cells to become crescent or sickle-shaped and sticky. A person with one mutated copy sickle cell gene does not show any symptoms of the disease and does not require treatment. In fact, having one copy of the mutant gene is common in tropical countries where malaria is endemic because it actually protects against malaria; it is fairly common in people of African, Indian, Mediterranean and Middle Eastern descent.

67. Pain Resource Center :: Beckman Research Institute :: City Of Hope
    3. Guideline for the Management of Acute Pain in sickle cell disease, Quick ReferenceGuide for Emergency Department Clinicians (2001 version) order form.  
    http://mayday.coh.org/sickle.asp
    
    Extractions: - Sickle Cell Advisory Committee. Trenton, NJ: Special Child, Adult and Intervention Services, New Jersey Department of Health and Senior Services, September, 1999. C. Educational Materials/Curriculum 1. Sickle Cell Provider Video Course order form - Georgia Sickle Cell Center, Grady Health System, Atlanta, Georia. Includes a 10-hour course designed to educate health care providers about the latest developments in common clinical issues in sickle cell disease treatment. D. Guidelines/Clinical Pathways 1. Guideline for the Management of Acute and Chronic Pain in Sickle Cell Disease, 1999 version - American Pain Society publication guideline. Order guideline at http://www.ampainsoc.org/pub/sc.htm

68. ICT - Sickle Cell
    What is sickle cell disease? sickle cell disease is caused by a small changein a hemoglobin protein contained in red blood cells (RBC's).  
    http://ict.louisville.edu/bedside/sc/
    
    Extractions: Sickle cell disease is caused by a small change in a hemoglobin protein contained in red blood cells (RBC's). This change causes the shape of the RBCs to be flat and curved into a sickle shape instead of the normal doughnut shape. These sickled cells do not pass smoothly through the smallest blood vessels causing many serious medical problems including blood clots, severe pain, and stroke, as well as heart attack, and liver, kidney and spleen damage. More About Sickle Cell Disease The abnormal RBC's in sickle cell disease, like all other blood cells, are produced in the bone marrow. A bone marrow transplant (BMT) can cure sickle cell disease by replacing the marrow that is manufacturing the abnormal cells. However, until now BMT has not been widely used for this purpose because severe complications can result. The Institute's approach to BMT may make it much safer by treating the donor bone marrow to remove harmful cells. More About BMT and Mixed Chimerism The Institute's clinical trial for sickle cell disease will use partial conditioning and a specially modified bone marrow transplant procedure to create "chimerism". This procedure allows both your own bone marrow and the new transplanted bone marrow to live together in your body. The purpose of this study will be to evaluate the effectiveness of "Mixed Chimerism" to treat sickle cell disease.

69. TUP: Hill, Shirley A.: Managing Sickle Cell Disease In Low-Income Families
    Managing sickle cell disease in LowIncome Families. Shirley A. Hill. Asmany as 30,000 African Americans have sickle cell disease (SCD).  
    http://www.temple.edu/tempress/titles/1113_reg.html
    
    Extractions: Peter Conrad , Brandeis University As many as 30,000 African Americans have sickle cell disease (SCD). Though the political activism of the 1960s and a major 1970s health campaign spurred demands for testing, treatment, and education programs, little attention has been given to how families cope with SCD. This first study to give SCD a social, economic, and cultural context documents the daily lives of families living with this threatening illness. Specifically, Shirley A. Hill examines how low-income African American mothers with children suffering from this hereditary, incurable, and chronically painful disease, react to the diagnosis and manage their family's health care. The 23 mostly single mothers Hill studies survive in an inner-city world of social inequality. Despite limited means, they actively participate, create, and define the social world they live in, their reality shaped by day-to-day caregiving. These women overcome obstacles by utilizing such viable alternatives as sharing child care with relatives within established kinship networks.

70. BBC News | HEALTH | Gene Therapy Hope For Sickle Cell Disease
    Scientists have been able to correct sickle cell diseasein mice using gene therapy.  
    http://news.bbc.co.uk/hi/english/health/newsid_1708000/1708055.stm
    
    Extractions: Scientists have been able to correct sickle cell disease in mice using gene therapy. The American researchers who carried out the tests say there are several hurdles to be overcome before the therapy can be used in humans, but that it offers hope for the future. The research, detailed in the journal Science, shows how the gene therapy counteracts the faulty gene that causes red blood cells to "sickle", or become deformed. The treatment involves the "anti-sickling" variant being delivered into bone marrow; it then incorporates itself into the stem cells that give rise to red blood cells. 'Sticky' cells Sickle cell anaemia is an inherited blood disorder, which largely affects Afro-Caribbean and Asian patients, named after the distinctive shape formed by red blood cells. The shape is affected because a protein within the cells - haemoglobin which carries oxygen from the lungs to the rest of the body - is different to normal.

71. Division Of Genetics: Sickle Selections, URMC
    April 2002 Survey of Newborns with sickle cell disease, Birth Statistics, Camp KopeSchedule*. January 2002 sickle cell disease Cured in Mice by Gene Therapy*.  
    http://www.urmc.rochester.edu/genetics/hemonews.htm
    
    Extractions: Department of Medicine a quarterly newsletter from the University of Rochester Sickle Cell Program The following newsletters are available as Adobe Acrobat Reader 3.0 files - online versions that look just like the originals. The Adobe Acrobat Reader software is freely available for you to download and use from Adobe's software site. April 2002

72. Sickle Cell Disease - Health Risk Factors
    sickle cell disease. About sickle cell disease. sickle cell diseaseis an inherited disorder of the red blood cells. Red blood cells  
    http://www.agingwell.state.ny.us/prevention/sickle.htm
    
    Extractions: Common Risk Factors Sickle Cell Disease Sickle cell disease is an inherited disorder of the red blood cells. Red blood cells carry oxygen to all parts of the body by using a protein called hemoglobin. Normal red blood cells contain only normal hemoglobin and are shaped like doughnuts. These cells are very flexible and move easily through small blood vessels. But in sickle cell disease, the red blood cells contain sickle hemoglobin, which causes them to change to a curved shape (sickle shape) after oxygen is released. Sickled cells become stuck and form plugs in small blood vessels. This blockage of blood flow can damage the tissue. Because there are blood vessels in all parts of the body, damage can occur anywhere in the body. The most common types of sickle cell disease are: Source: U.S. Agency for Healthcare Research and Quality

73. What Is Sickle Cell Disease?
    Provides easyto-understand explanations of sickle cell disease and a descriptionof how the body reacts to this inherited disorder.  
    http://www.ahcpr.gov/consumer/bodysys/edbody12.htm
    
    Extractions: Sickle cell disease is an inherited disorder of the red blood cells. Red blood cells carry oxygen to all parts of the body by using a protein called hemoglobin. Normal red blood cells contain only normal hemoglobin and are shaped like doughnuts. These cells are very flexible and move easily through small blood vessels. But in sickle cell disease, the red blood cells contain sickle hemoglobin, which causes them to change to a curved shape (sickle shape) after oxygen is released. Sickled cells become stuck and form plugs in small blood vessels. This blockage of blood flow can damage the tissue. Because there are blood vessels in all parts of the body, damage can occur anywhere in the body. The most common types of sickle cell disease are: Current as of August 2000 Internet Citation: Understanding Your Body: What Is Sickle Cell Disease? August 2000. Life Sciences Education and Health Literacy. Agency for Healthcare Research and Quality, Rockville, MD. http://www.ahrq.gov/consumer/bodysys/edbody12.htm Return to Understanding Your Body

74. Hardin MD : Sickle Cell Anemia
    updated Friday, Mar 14, 2003 sickle cell pictures, pictures of sickle cell anemia,information on sickle cell anemia, sickle cell disease pictures, sickle  
    http://www.lib.uiowa.edu/hardin/md/sicklecellanemia.html

75. CBC News:Father Calls Sickle Cell Anemia 'neglected' Disease
    The Sickle Cell Foundation of Alberta; sickle cell disease Mount Sinai Hospital.(Note CBC does not endorse and is not responsible for the content of external  
    http://www.cbc.ca/storyview/AOL/2003/03/17/sickle_cell030317
    
    Extractions: Last Updated Mon, 17 Mar 2003 19:30:49 MONTREAL - Sickle cell anemia is the most common genetic disease in the world, but Canada has few specialized centres to treat adults. The debilitating disease mainly affects people of African descent. Sickle cell anemia causes malformed red blood cells that block tiny blood vessels. In sickle cell anemia, blood cells are elongated instead of round Oxygen flow to tissues is reduced, producing episodes of acute pain, as well as complications including blindness and heart, kidney and liver failure. Pediatric patients often have a procedure called erythropheresis, an exchange of red blood cells to keep the disease under control. Every four to six weeks, Melissa Maurice Carrenard, 21, has the procedure. When she left the children's hospital that specialized in her condition, general practitioners took over her care. Wilson Sanon's 11-year-old daughter has sickle cell anemia. Sanon said he's sending a cry of alarm for what he calls a neglected disease. No one knows how many people are affected by sickle cell anemia, because Health Canada doesn't keep any statistics on the disease.

76. The Sickle Cell Disease Program At St. Louis Children’s Hospital.
    The sickle cell disease Program at St. Louis Children’s Hospitalprovides comprehensive diagnosis sickle cell disease Program.  
    http://www.stlouischildrens.org/articles/kids_parents.asp?ID=247

77. Wadsworth-Newborn Screening-Sickle Cell
    Anemia). If he inherits an 'IS gene from one parent and a IICII genefrom the other, he has SC Disease, a form of sickle cell disease.  
    http://www.wadsworth.org/newborn/scell/scell.htm
    
    Extractions: SICKLE CELL TRAIT If you've been told, as the result of a blood test, that your child has Sickle Cell Trait, quite naturally, you're concerned. Questions are tumbling through your head. "What does it mean?" "Is the baby sick?" "Can it develop into Sickle Cell Anemia?" "Can other members of my family get it?" Your Baby is Not Sick First of all let us assure you that Sickle Cell Trait will not affect your baby's health. YOUR INFANT DOES NOT HAVE SICKLE CELL ANEMIA AND WILL NEVER DEVELOP THIS DISEASE. Your Baby Inherited the Trait Sickle Cell Trait, like hair color, general body build and other physical characteristics is passed down in the family from parent to child through the genes. Genes are the tiny bits of information contained in the father's sperm and the mother's egg that form a blueprint for the new life. Genes come in pairs; for each characteristic there is one gene from the mother and one form the father. One of these pairs of genes determines hemoglobin the substance that carries oxygen in your blood and gives it its red color. If your baby has Sickle Cell Trait, it means that the baby inherited a normal hemoglobin gene from one parent and a changed or altered hemoglobin gene from the other parent. We refer to the usual gene as "All and the changed gene as 'IS." Your baby, therefore, has AS hemoglobin.

78. Newborn Screening Brochurs And Educational Materials - New York State Department
    sickle cell disease (sickle cell anemia or homozygous S disease)a disorder ofthe hemoglobin (oxygencarrying part) of red blood cellsnot to be confused  
    http://www.wadsworth.org/newborn/disorders.htm
    
    Extractions: Disorders Identified by the New York State Newborn Screening Program Biotinidase deficiency (bio-TIN-i-dase)lack of an enzyme (biotinidase) prevents the body from properly absorbing or recycling the vitamin biotin. Severe skin rashes, vision and hearing impairment, and brain damage can be prevented by special biotin supplements given daily. Occurs in about 1 of every 80,000 newborns. Branched-chain ketonuria (branched-chain KEE-tone-u-ree-ah)also called maple syrup urine disease (MSUD) because the urine has a maple syrup-like odor resulting from the body's inability to break down some components of food protein. Again, this is due to the lack of an enzyme. Treatment with a special diet can prevent life-threatening complications. Occurs in about 1 of every 268,000 newborns. Galactosemia (ga-LAK-toe-see-me-a)a milk sugar (galactose) cannot be broken down by the body due to the lack of an enzyme. A diet low in galactose can prevent life-threatening complications. Occurs in about 1 of every 57,000 newborns. HIV (Human Immunodeficiency Virus) HIV is the virus that causes AIDS. The test checks for the presence of HIV antibodies. If a baby is HIV positive, this means that the mother is infected with HIV in all cases, and that the baby has been exposed to the virus. Only a quarter of babies who were exposed to HIV actually have infection. HIV positive newborns should have special medical care and need repeat testing to see if they are infected. Their mothers also need special medical care.

79. American Red Cross, Penn-Jersey Region Sickle Cell Disease
    Donate blood, help a child with sickle cell disease,American Red Cross PennJersey Region.  
    http://www.pleasegiveblood.org/donating/sickle_cell.html

80. HuGE Review - Sickle Hemoglobin (Hb S) Allele And Sickle Cell Disease
    Sickle Hemoglobin (Hb S) Allele and sickle cell disease print version. Most individualswith sickle cell disease have African and Mediterranean ancestry.  
    http://www.cdc.gov/genomics/hugenet/reviews/sickle.htm
    
    Extractions: Medical Literature Search At-A-Glance Beta globin is a major component of adult hemoglobin. The gene for beta globin is located on chromosome 11 and there are over 475 allelic variants. One of these variants, sickle hemoglobin ( Hb S ), is responsible for sickle cell disease, one of the most prevalent genetic diseases, affecting over 50,000 Americans. Most individuals with sickle cell disease have African and Mediterranean ancestry. It is believed that the high frequency of the (

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