MEDLINEplus Medical Encyclopedia: Thromboangiitis Obliterans The alternative names, causes, incidence and risk factors of thromboangiitis obliterans.Category Health Conditions and Diseases thromboangiitis obliteransthromboangiitis obliterans. Definition Return to top thromboangiitis obliterans isa disease that causes obstruction of the blood vessels of the hands and feet. http://www.nlm.nih.gov/medlineplus/ency/article/000172.htm
Extractions: Skip navigation Other encyclopedia topics: A-Ag Ah-Ap Aq-Az B-Bk ... Z Contents of this page: Thromboangiites obliterans Circulatory system Alternative names Return to top Buerger's disease Definition Return to top Thromboangiitis obliterans is a disease that causes obstruction of the blood vessels of the hands and feet. Causes, incidence, and risk factors Return to top Thromboangiitis obliterans (Buerger's disease) is caused by vasculitis, which is an inflammation (irritation with presence of extra immune cells) of blood vessels. The blood vessels of the hands and feet are especially affected, becoming constricted or totally blocked. This reduces blood flow to the tissues of hands and feet, resulting in pain and eventually damage. Thromboangiitis obliterans affects approximately 6 out of every 10,000 people. It almost always affects men aged 20 to 40 years old who have a history of smoking or chewing tobacco.
Extractions: This Publication Is Searchable The Merck Manual of Diagnosis and Therapy Section 16. Cardiovascular Disorders Chapter 212. Peripheral Vascular Disorders Topics [General] Peripheral Arterial Occlusion Thromboangiitis Obliterans Raynaud's Disease and Phenomenon ... Lipedema Thromboangiitis Obliterans (Buerger's Disease) An obliterative disease characterized by inflammatory changes in small and medium-sized arteries and veins. Thromboangiitis obliterans occurs in cigarette smokers, predominantly in men aged 20 to 40. Only about 5% of cases occur in women. The frequency of diagnosis has decreased drastically in recent years because of better understanding of clinical and angiographic characteristics of this disease vs. arteriosclerosis obliterans. Although few investigators believe this disease is indistinguishable pathologically from occlusive disease caused by some types of atherosclerosis, idiopathic peripheral thromboses, or systemic emboli, most clinicians agree that the clinical characteristics are sufficiently distinctive to consider thromboangiitis obliterans a discrete entity. Although the cause is unknown, thromboangiitis obliterans has not been documented in nonsmokers, implicating cigarette smoking as a primary etiologic factor, perhaps as a delayed type of hypersensitivity or toxic angiitis. Thromboangiitis obliterans may be a reaction to tobacco by persons with a specific phenotype, because of greater prevalence of HLA-A9 and HLA-B5 in persons with the disease; or an autoimmune disorder with cell-mediated sensitivity to types I and III human collagen, which are constituents of blood vessels.
Extractions: Tips from Other Journals Previous Next Update on Thromboangiitis Obliterans (Buerger's Disease) Thromboangiitis obliterans, also known as Buerger's disease, is a nonatherosclerotic inflammatory disease of the small-sized and medium-sized arteries and veins of the arms and legs. Although inflammatory by nature, it spares the blood vessel walls. Unlike other types of vasculitis, the acute-phase reactants (such as the erythrocyte sedimentation rate and C-reactive protein) are normal in patients with Buerger's disease. A pathologic finding of acute disease is an occlusive, highly cellular, inflammatory thrombus. The disease is found worldwide, but the highest incidence of thromboangiitis obliterans occurs in the Middle East and Far East. Prevalence ranges from about 12 percent in the United States to 63 percent in India to 80 percent among Jews of Ashkenazi ancestry living in Israel. Part of this difference in disease incidence may be due to variability in diagnostic criteria. Olin reviewed the current concepts of this disease. Although the cause of Buerger's disease is unknown, the strongest association is with tobacco use. Occurrences of the disease have been reported, but uncommonly, in persons who use smokeless tobacco or snuff. A current or previous history of smoking is usually a required diagnostic criterion.
Resume-96-t1-res8-a Pseudothromboangiitis obliterans and qualitative protein C defect a case report. thromboangiitis obliterans is a segmental obliterating inflammatory arteritis, usually found in young (below 40) smoking males. http://www-sante.ujf-grenoble.fr/SANTE/jmv/jmv-a/1996-a/96tome1-a/96-t1-res8-a.h
MEDLINEplus Medical Encyclopedia: Thromboangiites Obliterans Medical Encyclopedia. Thromboangiites obliterans. thromboangiitis obliterans is adisorder that leads to obstruction of the blood vessels of the hands and feet. http://www.nlm.nih.gov/medlineplus/ency/imagepages/18089.htm
Extractions: Skip navigation Thromboangiites obliterans Thromboangiitis obliterans is a disorder that leads to obstruction of the blood vessels of the hands and feet. The blood vessels become constricted or totally obstructed because of the inflammation and clots which reduces the availability of blood to the tissues. Thromboangiitis obliterans almost always affects men, 20 to 40 years old, who have a history of smoking or chewing tobacco.
Extractions: First Description thromboangiitis obliterans (top of page) (top of page) Classic symptoms and signs of Buerger's Disease pictured below ) of the digits (fingers and toes) are common in Buergers disease. Pain may be very intense in the affected regions. An angiogram demonstrating lack of blood flow to vessels of the hand ( figure below A normal angiogram of the hand ( figure below Despite the severity of ischemia (lack of blood flow) to the distal extremities that occurs in Buergers, the disease does not involve other organs, unlike many other forms of vasculitis. Even as ulcers and gangrene develop in the digits, organs such as the lung, kidneys, brain, and gastrointestinal (GI) tract remain unaffected. The reasons for the confinement to the extremities and sparing of other organs are not known. (top of page) What Causes Buerger's Disease? Pictured below , are a patient's fingertips that have developed gangrene. This is a very painful condition which sometimes requires amputation of the affected area.
THE MERCK MANUAL, Sec. 16, Ch. 212, Peripheral Vascular Disorders A description of raynaud's phenomenon as well as the symptoms, diagnosis and treatment.Category Health Conditions and Diseases Raynaud s Phenomenon as connective tissue disorders (scleroderma, RA, SLE), obstructive arterial diseases(arteriosclerosis obliterans, thromboangiitis obliterans, thoracic outlet http://www.merck.com/pubs/mmanual/section16/chapter212/212d.htm
Extractions: This Publication Is Searchable The Merck Manual of Diagnosis and Therapy Section 16. Cardiovascular Disorders Chapter 212. Peripheral Vascular Disorders Topics [General] Peripheral Arterial Occlusion Thromboangiitis Obliterans Raynaud's Disease and Phenomenon ... Lipedema Raynaud's Disease and Phenomenon Spasm of arterioles, usually in the digits and occasionally in other acral parts (eg, nose, tongue), with intermittent pallor or cyanosis. Raynaud's disease, most common in young women (60 to 90% of reported cases), is idiopathic. Raynaud's phenomenon is secondary to other conditions, such as connective tissue disorders (scleroderma, RA, SLE), obstructive arterial diseases (arteriosclerosis obliterans, thromboangiitis obliterans, thoracic outlet syndrome), neurogenic lesions, drug intoxications (ergot, methysergide), dysproteinemias, myxedema, primary pulmonary hypertension, and trauma. Pathology and Pathophysiology Although the pathogenesis of Raynaud's disease remains uncertain, research into prostaglandin metabolism, microcirculation, and the role of the endothelial cell is yielding promising results. Raynaud's phenomenon is associated clinically with migraine headaches, variant angina, and pulmonary hypertension, suggesting that these disorders may share a common vasospastic mechanism. In Raynaud's disease
Extractions: (advertisement) Home Specialties CME PDA ... Patient Education Articles Images CME Patient Education Advanced Search Link to this site Back to: eMedicine Specialties Medicine, Ob/Gyn, Psychiatry, and Surgery Vascular Surgery Last Updated: October 17, 2002 Rate this Article Email to a Colleague Synonyms and related keywords: Buergers disease, TAO, endarteritis, endophlebitis, vasoocclusive disease, presenile spontaneous gangrene, corkscrew collaterals, bidi, cigarette smoking, tobacco use, secondhand smoke, smoking cessation, distal ischemic rest pain, ischemic ulcerations, amputation AUTHOR INFORMATION Section 1 of 11 Author Information Introduction Clinical Differentials ... Bibliography Author: Eric J Hanly, MD , Research Instructor, Department of Surgery, Uniformed Services University of the Health Sciences; Fellow, Department of Surgery, Johns Hopkins University School of Medicine Coauthor(s): Matthew Carpenter, MD , Program Director, Department of Internal Medicine, Keesler Medical Center; Assistant Clinical Professor, Department of Internal Medicine, F Edward Hebert College of Medicine; E Jerry Cohn, Jr, MD
Definition For:Buerger Disease, (thromboangiitis Obliterans): Buerger disease, (thromboangiitis obliterans) An occlusive, inflammatory disease of the mediumsized and small arteries in the distal arms and legs. Patients are usually young or middle-aged male smokers. http://www.kumc.edu/instruction/medicine/pathology/ed/keywords/kw_buerger.html
Extractions: An occlusive, inflammatory disease of the medium-sized and small arteries in the distal arms and legs. Patients are usually young or middle-aged male smokers. Symptoms typically include intermittent claudication (cramping, muscular pain following exercise, relieved by rest). Microscopically, there is acute inflammation of arteries with thrombosis and obliteration of lumen.
Extractions: Home About Links Index ... Editor's Choice Paid Advertisement (click above). Please see the privacy statement Rheumatology Cardiovascular Medicine Assorted Pages Thromboangiitis Obliterans Vasculitis Small Vessel Vasculitis Microscopic Polyangiitis Thromboangiitis Obliterans Buerger's Disease Buergers Disease Book Home Page Cardiovascular Medicine Dental Dermatology Emergency Medicine Endocrinology Gastroenterology General Medicine Geriatric Medicine Gynecology Hematology and Oncology HIV Infectious Disease Jokes Laboratory Neonatology Nephrology Neurology Obstetrics Ophthalmology Orthopedics Otolaryngology Pediatrics Pharmacology Prevention Psychiatry Pulmonology Radiology Rheumatology Sports Medicine Surgery Urology Chapter Rheumatology Index Bone Cardiovascular Medicine Diffuse Examination Infectious Disease Intra-Articular Disorders Laboratory General Marfans Myofascial Neurology Osteoarthritis Pain Pediatrics Pharmacology Procedure Radiology RA Spondylitis Symptom Evaluation Page Cardiovascular Medicine Index Environ Raynauds Thromboangiitis Obliterans Vasculitis Vasculitis Small Vasculitis Small Polyangiitis Epidemiology Age of onset: Younger than 45 years old Men predominate Prevalence (asian and eastern european descent) United States: 12% India: 63% Ashkenazi Jews in Israel: 80% Pathophysiology Nonatherosclerotic inflammatory disease Affects small and medium sized extremity vessels Risk factors Tobacco Abuse is highly correlated Symptoms Ischemia of distal extremities (hands and feet) Claudication Rest pain Ulcerations of toes and fingers Signs
Extractions: Worldbook Medical Encyclopedia Tabes dorsalis - Typhus Thromboangiitis obliterans Thromboangiitis obliterans Search the Web with All Surfable Books World Book Encyclopedia 2000 World Book Medical Encyclopedia Geography History Humanities Industry and Technology Life Science Physical Science and Math Recreation Social Science Documents 11 - 20 of 34 on the subject : Thromboangiitis obliterans Public Educational Sources News and Magazines Encyclopedias Health Ency.: Disease : Thromboangiitis obliterans Health Ency.: Disease : Thromboangiitis obliterans ... Causes and Risks. Thromboangiitis obliterans ( Buergers disease ) is a disorder where ... prone to infections and gangrene . Thromboangiitis obliterans affects ...
Cardiovascular Medicine Rheumatology Cardiovascular Medicine Look here for Raynaud'sPhenomenon, thromboangiitis obliterans and Vasculitis. http://www.fpnotebook.com/RHECh2.htm
Extractions: Home About Links Index ... Editor's Choice Paid Advertisement (click above). Please see the privacy statement Rheumatology Bone Cardiovascular Medicine Diffuse Examination Infectious Disease Intra-Articular Disorders ... Symptom Evaluation Cardiovascular Medicine Chapter Book Home Page Cardiovascular Medicine Dental Dermatology Emergency Medicine Endocrinology Gastroenterology General Medicine Geriatric Medicine Gynecology Hematology and Oncology HIV Infectious Disease Jokes Laboratory Neonatology Nephrology Neurology Obstetrics Ophthalmology Orthopedics Otolaryngology Pediatrics Pharmacology Prevention Psychiatry Pulmonology Radiology Rheumatology Sports Medicine Surgery Urology Chapter Rheumatology Index Bone Cardiovascular Medicine Diffuse Examination Infectious Disease Intra-Articular Disorders Laboratory General Marfans Myofascial Neurology Osteoarthritis Pain Pediatrics Pharmacology Procedure Radiology RA Spondylitis Symptom Evaluation Page Cardiovascular Medicine Index Environ Raynauds Thromboangiitis Obliterans Vasculitis Vasculitis Small Vasculitis Small Polyangiitis Assorted Pages in Cardiovascular Medicine Related Topics from other Books Chapters in Cardiovascular Medicine Arrhythmia Coronary Artery Disease Congestive Heart Failure EKG Examination Ophthalmology Hypertension Infectious Disease Laboratory General Hyperlipidemia Pulmonology Myocardium Neurology Neonatology Obstetrics Pediatrics Pericardium Pharmacology Prevention Procedure Radiology
Extractions: Home About Links Index ... Editor's Choice Paid Advertisement (click above). Please see the privacy statement Rheumatology Cardiovascular Medicine Assorted Pages Thromboangiitis Obliterans Vasculitis Small Vessel Vasculitis Microscopic Polyangiitis Thromboangiitis Obliterans Buerger's Disease Buergers Disease Book Home Page Cardiovascular Medicine Dental Dermatology Emergency Medicine Endocrinology Gastroenterology General Medicine Geriatric Medicine Gynecology Hematology and Oncology HIV Infectious Disease Jokes Laboratory Neonatology Nephrology Neurology Obstetrics Ophthalmology Orthopedics Otolaryngology Pediatrics Pharmacology Prevention Psychiatry Pulmonology Radiology Rheumatology Sports Medicine Surgery Urology Chapter Rheumatology Index Bone Cardiovascular Medicine Diffuse Examination Infectious Disease Intra-Articular Disorders Laboratory General Marfans Myofascial Neurology Osteoarthritis Pain Pediatrics Pharmacology Procedure Radiology RA Spondylitis Symptom Evaluation Page Cardiovascular Medicine Index Environ Raynauds Thromboangiitis Obliterans Vasculitis Vasculitis Small Vasculitis Small Polyangiitis Epidemiology Age of onset: Younger than 45 years old Men predominate Prevalence (asian and eastern european descent) United States: 12% India: 63% Ashkenazi Jews in Israel: 80% Pathophysiology Nonatherosclerotic inflammatory disease Affects small and medium sized extremity vessels Risk factors Tobacco Abuse is highly correlated Symptoms Ischemia of distal extremities (hands and feet) Claudication Rest pain Ulcerations of toes and fingers Signs
Thromboangiitis Obliterans -- ECureMe.com thromboangiitis obliterans, Normal, Abnormal, thromboangiitis obliterans is alsoknown as Buerger's disease, and it is most often seen in young men who smoke. http://www.ecureme.com/emyhealth/data/Thromboangiitis_Obliterans.asp
Extractions: March 31, 2003 Select a Health Topic ADD/ADHD Allergy Alternative Medicine Arthritis Asthma Beyond Dieting Body Aches and Pains Breast Cancer Cancer Awareness Cardio Health Children's Health Colon Cancer Contraception COPD/Emphysema Dental Health Diabetes Elder Care Emergency Room Epilepsy Erectile Dysfunction Eye Care Fertility Fitness Gastrointestinal Health Glands and Hormones Gynecologic Health Hair Loss Headache Healthcare Today Healthy Aging HIV and AIDS Infectious Diseases Kidney Health Leukemia Liver Health Lung Cancer Lymphoma Multiple Sclerosis Men's Health Mental Health Nutrition Osteoporosis Parkinson's Disease Sexual Health Skin Health Sleep Disorders Special Events Stroke Surgeries and Procedures Teen Health Thyroid Health Urologic Health Vascular Disease Women's Health Workplace Health Abnormal Thromboangiitis obliterans is also known as Buerger's disease, and it is most often seen in young men who smoke. This disease causes blood circulation to the hands and feet to cut off, leading to pain, numbness, infections, and/or loss of the affected limb. Treatment is to stop smoking immediately and to take care of the limbs.
Extractions: 1Up Health Thromboangiitis obliterans Alternative Medicine Clinical Trials ... Health Topics A-Z Search 1Up Health Thromboangiitis obliterans Information Thromboangiitis obliterans Causes, Incidence, and Risk Factors Alternative names : Buerger's disease Definition : Thromboangiitis obliterans is a disease that causes obstruction of the blood vessels of the hands and feet. Thromboangiitis obliterans (Buerger's disease) is caused by vasculitis, which is an inflammation (irritation with presence of extra immune cells) of blood vessels. The blood vessels of the hands and feet are especially affected, becoming constricted or totally blocked. This reduces blood flow to the tissues of hands and feet, resulting in pain and eventually damage. Thromboangiitis obliterans affects approximately 6 out of every 10,000 people. It almost always affects men aged 20 to 40 years old who have a history of smoking or chewing tobacco. The condition may also be associated with a history of Raynaud's disease . This disorder is very uncommon in children, but may occur in those with
Extractions: 1Up Health Alternative Medicine Clinical Trials Health News ... Health Topics A-Z Search 1Up Health Thromboangiitis obliterans Information Guide Alternative names : Buerger's disease Definition : Thromboangiitis obliterans is a disease that causes obstruction of the blood vessels of the hands and feet. A.D.A.M., Inc. is accredited by URAC, also known as the American Accreditation HealthCare Commission (www.urac.org). URAC's accreditation program is the first of its kind, requiring compliance with 53 standards of quality and accountability, verified by independent audit. A.D.A.M. is among the first to achieve this important distinction for online health information and services. Learn more about A.D.A.M.'s editorial reviewers . A.D.A.M. is also a founding member of Hi-Ethics (www.hiethics.com) and subscribes to the principles of the Health on the Net Foundation (www.hon.ch).