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Neuroleptic malignant syndrome (NMS) and other hyperthermic conditions are rare complications of antipsychotic drugs that can cause discomfort, disability, and even death. As a result, every psychiatrist, physician, and mental health care professional needs to be able to spot warning signs of NMS and to administer treatment in time to prevent a fatal outcome.Neuroleptic Malignant Syndrome and Related Conditions is an important tool for clinicians, outlining a framework for understanding, diagnosing, treating, and preventing these little-understood and often overlapping disorders. This new second edition extensively updates and revises the first edition, integrating an explosion of new findings that have occurred since the earlier edition was published in 1989.

A new chapter on serotonin syndrome is particularly important, given the rise in use of serotonergic drugs such as Selective Serotonin Reuptake Inhibitors (SSRIs). It is the first comprehensive review of this condition to appear in the world literature.

Other chapters focus on related conditions such as antipsychotic drug–related heatstroke, hyperthermia associated with other neuropsychiatric drugs, and malignant catatonia. The heatstroke chapter contains a detailed consideration of thermoregulatory mechanisms, the disruption of which could underlie the pathogenesis of all these conditions.

Written by four internationally renowned authorities on NMS, Neuroleptic Malignant Syndrome and Related Conditions will equip clinicians with a practical approach based on the most current science. In addition, this balanced monograph will stimulate research, with coverage of controversies and unanswered questions to provide direction for future study. ... Read more

Customer Reviews (1)

Great, but a little old
This is the only book I could find on the subject. It is an excellent review of the diagnosis, differential diagnosis and management of NMS. I recommend it highly. The only thing I could wish for is that it be updated. ... Read more

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In March 2001, the National Institutes of Health issued the following warning: "The number of Web sites offering health-related resources grows every day. Many sites provide valuable information, while others may have information that is unreliable or misleading."Furthermore, because of the rapid increase in Internet-based information, many hours can be wasted searching, selecting, and printing.This book was created for medical professionals, students, and members of the general public who want to conduct medical research using the most advanced tools available and spending the least amount of time doing so. ... Read more

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High Quality Content by WIKIPEDIA articles! There is no consensus on the treatment of schizophrenia although criteria for the remission of symptoms were suggested in 2006. Management of symptoms and improving function may be more achievable than a cure. A recovery model is increasingly adopted, emphasizing hope, empowerment and social inclusion.?Odysseus labours? is a handbook for friends and families to provide services, support and rehabilitation for people with serious mental illness including schizophrenia, and was written by Dr Paul Kauffman and Rupert Gerritsen in 2008. It is available free on www.mhf.org.au. Antipsychotics have been a mainstay of therapy since the introduction of chlorpromazine in the mid 1950s, which revolutionized treatment. Side effects (some harmful or fatal) have attracted controversy. Older concerns over sedation, tardive dyskinesia and neuroleptic malignant syndrome have been largely replaced with those of drug-related obesity and diabetes. ... Read more

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Chapters: Neuroleptic Malignant Syndrome, Essential Tremor, Restless Legs Syndrome, Dystonia, Spasmodic Torticollis, Myoclonus, Tardive Dyskinesia, Multiple System Atrophy, Progressive Supranuclear Palsy, Pantothenate Kinase-Associated Neurodegeneration, Akathisia, Blepharospasm, Parkinsonism, Meige's Syndrome, Stiff Person Syndrome, Choreia, Movement Disorder, Postencephalitic Parkinsonism, Mohr-Tranebjaerg Syndrome, Status Dystonicus. Source: Wikipedia. Pages: 124. Not illustrated. Free updates online. Purchase includes a free trial membership in the publisher's book club where you can select from more than a million books without charge. Excerpt: Restless legs syndrome (RLS), also known as Wittmaack-Ekbom's syndrome, is a condition that is characterized by an irresistible urge to move one's body to stop uncomfortable or odd sensations. It most commonly affects the legs, but can also affect the arms or torso, and even phantom limbs. Moving the affected body part modulates the sensations, providing temporary relief. RLS causes a sensation in the legs or arms that can most closely be compared to a burning, itching, or tickling sensation in the muscles. Some controversy surrounds the marketing of drug treatments for RLS. It is a 'spectrum' disease with some people experiencing only a minor annoyance and others experiencing major issues. The sensationsand the need to movemay return immediately after ceasing movement or at a later time. RLS may start at any age, including early childhood, and is a progressive disease for a certain portion of those afflicted, although the symptoms have disappeared permanently in some sufferers. The sensations are unusual and unlike other common sensations, and those with RLS have a hard time describing them. People use words such as: uncomfortable, "antsy", electrical, creeping, painful, itching, pins and needles, pulling, creepy-crawly, ants inside the legs, numbness, and many others. It is som...More: http://booksllc.net/?id=240832 ... Read more

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This digital document is an article from Journal of Neuroscience Nursing, published by Thomson Gale on June 1, 2005. The length of the article is 1961 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser.

Citation Details
Title: Neuroleptic malignant syndrome in a patient with Parkinson's disease: a case study.
Author: Constance Ward
Publication: Journal of Neuroscience Nursing (Magazine/Journal)
Date: June 1, 2005
Publisher: Thomson Gale
Volume: 37Issue: 3Page: 160(3)

Distributed by Thomson Gale ... Read more

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Targeted to patients, their families and allied health students, The “Gale Encyclopedia of Neurological Disorders” provides in-depth coverage of neurological diseases and disorders, including stroke, multiple sclerosis, Parkinson disease, Tourette Syndrome, Alzheimer's disease, cerebral palsy, vertigo, amnesia and epilepsy. Related topics include communication aids, electric personal assistive mobility devices, medications for treating neurological diseases and conditions, understanding the needs of Alzheimer patient caregivers and more. This two-volume set provides an alternative to resources that either fail to explore neurological disease in any depth and or do so at a level not appropriate for students and general readers.

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This digital document is an article from Southern Medical Journal, published by Southern Medical Association on January 1, 2005. The length of the article is 3142 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser.

Citation Details
Title: Atypical neuroleptic malignant syndrome presenting as fever of unknown origin in the elderly.(Case Report)
Author: Ryan C.W. Hall
Publication: Southern Medical Journal (Refereed)
Date: January 1, 2005
Publisher: Southern Medical Association
Volume: 98Issue: 1Page: 114(4)

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This authoritative and comprehensive new publication looks in depth at a range of medical syndromes characterized by serious and unpredicted internal overheating of the body. As a result of heat stress, exceptional physical exertion, or in response to certain drugs, these episodes may arise suddenly and unexpectedly, with life-threatening consequences. This text's contributions focus on the full range of these syndromes, their metabolic and physiological bases, the important predisposing factors that determine those at risk, and the medical management of these conditions. The volume incorporates a wealth of information from the Leeds Malignant Hyperthermia Investigation Unit--the world's leading center of research and investigation in this area. ... Read more

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The understanding of drug-induced movement disorders is extremely difficult, and many physicians and clinicians find this a difficult and complex area to treat. The unique way in which the plethora of different drugs react and manifest with the patient’s exact condition is particularly hard to manage and diagnose. The effects of some of these drugs may suppress other symptoms that the patient may have, leading to confusion in the analysis of a patient’s care, especially when trying to avoid permanent movement disorders.

The second revised edition of this text will update and present current state of the art clinical approaches to this subject, assisting neurologists and physicians alike in this difficult but increasingly common situation.

This book will continue to be the source text of information on drug-induced movement disorders authored and edited by the pioneers in the field. It will be an invaluable addition to the library of any neurologist.The understanding of drug-induced movement disorders is extremely difficult, and many physicians and clinicians find this a difficult and complex area to treat. The unique way in which the plethora of different drugs react and manifest with the patient’s exact condition is particularly hard to manage and diagnose. The effects of some of these drugs may suppress other symptoms that the patient may have, leading to confusion in the analysis of a patient’s care, especially when trying to avoid permanent movement disorders. ... Read more

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The “Gale Encyclopedia of Mental Disorders” is a comprehensive two-volume set providing detailed information on mental disorders and conditions, in an easy-to-use format. It includes entries for all 150 disorders classified in the “Diagnostic and Statistical Manual of Mental Disorders,” and also features entries for prescription, alternative and over-the-counter drugs, as well as the various therapies used to treat mental disorders.