Book Description
This up-to-date and comprehensive CD-ROM provides a superb collection of official Federal government documents on childhood cancer: signs and symptoms, diagnosis, lab tests, treatment and management options, and ongoing clinical research. Every aspect of the disease is thoroughly covered. There is no other reference that is as fast, convenient, and portable - everything you need to know, from the federal sources you trust.Tumors covered include: Brain Tumor (Brain Stem Glioma, Cerebellar Astrocytoma, Cerebral Astrocytoma, Ependymoma, Medulloblastoma, Supratentorial Primitive Neuroectodermal and Pineal Tumors, Visual Pathway and Hypothalamic Glioma, Other Brain Tumors); Ewing's Sarcoma Family of Tumors; Germ Cell Tumor, Extracranial Hodgkin's Disease; Leukemia; Leukemia, Acute Lymphoblastic; Leukemia, Acute Myeloid; Liver Cancer; Neuroblastoma; Non-Hodgkin's Lymphoma; Osteosarcoma/Malignant Fibrous Histiocytoma of Bone; Retinoblastoma; Rhabdomyosarcoma; Soft Tissue Sarcoma; Unusual Childhood Cancers; Wilms' Tumor and Other Childhood Kidney Tumors.

For patients, practical information is provided in clearly written patient education documents. For medical professionals, doctor references and texts have detailed technical information and clinical background material. Documents from the National Cancer Institute, Centers for Disease Control and Prevention (CDC), Food and Drug Administration (FDA), and the National Institutes of Health (NIH) are included. In addition to disease-specific information, there is extensive coverage of the broad subject of cancer and its prevention and treatment along with current cancer research projects.

A unique feature is the inclusion of the results of a database search using the Combined Health Information Database (CHID).

Since navigating the Internet to find additional non-governmental medical information can be confusing and difficult, we've also provided our exclusive "Guide to Leading Medical Websites" with links to 80 of the best sites for general health and medical information! By using weblinks built into the documents reproduced on the CD-ROM, you can quickly and easily check for the latest clinical updates directly from the government.

In all, the disc has over 47,000 pages reproduced using Adobe Acrobat PDF software - allowing direct viewing on Windows and Apple Macintosh systems. Reader software is included on the CD.

Our CD-ROMs are designed to provide a convenient user-friendly reference work, utilizing the benefits of the Acrobat format to uniformly present thousands of pages that can be rapidly reviewed or printed without untold hours of tedious searching and downloading. Vast archives of important public domain government information that might otherwise remain inaccessible are available for instant review no matter where you are. (Information on this CD-ROM is not a substitute for professional medical advice; of course, readers are urged to consult with a professional health care provider for any suspected illness.) This book-on-a-disc makes a great reference work and educational tool for patients and their families, physicians, and other medical professionals. ... Read more

Download Description
This book has been created for parents who have decided to make education and research an integral part of the treatment process. Although it also gives information useful to doctors, caregivers and other health professionals, it tells parents where and how to look for information covering virtually all topics related to retinoblastoma (also Cancer retina; glioma retina; glioma retina child; Retina Glioma; Tumor retina child), from the essentials to the most advanced areas of research. The title of this book includes the word official. This reflects the fact that the sourcebook draws from public, academic, government, and peer-reviewed research. Selected readings from various agencies are reproduced to give you some of the latest official information available to date on retinoblastoma. Given parents' increasing sophistication in using the Internet, abundant references to reliable Internet-based resources are provided throughout this sourcebook. Where possible, guidance is provided on how to obtain free-of-charge, primary research results as well as more detailed information via the Internet. E-book and electronic versions of this sourcebook are fully interactive with each of the Internet sites mentioned (clicking on a hyperlink automatically opens your browser to the site indicated). Hard-copy users of this sourcebook can type cited Web addresses directly into their browsers to obtain access to the corresponding sites. In addition to extensive references accessible via the Internet, chapters include glossaries of technical or uncommon terms. ... Read more

Book Description

Information on many genetic disorders, and the frequent new findings on them, has been extremely difficult to come byuntil now. The Gale Encyclopedia of Genetic Disorders addresses the need for current, hard-to-find facts on emerging discoveries. The two-volume Encyclopedia, presented in a single alphabetical sequence, provides clear, complete information on genetic disorders, including conditions, tests, procedures, treatments and therapies, in articles that are both comprehensive and easy to understand, in language accessible to laypersons. The articles are arranged in a standardized format for quick comparison and ease of use, while non-disorder topics are covered in detail with extended entries. Students will want to consult the Gale Encyclopedia of Genetic Disorders for useful information on a range of well known disorders, including Down Syndrome, Trisomy, Hemophilia and Tourette Syndrome, and rarely seen diseases such as Meckel Syndrome, Neuraminidase Deficiency and Phenylketonuria.

Product Description
In March 2001, the National Institutes of Health issued the following warning: "The number of Web sites offering health-related resources grows every day. Many sites provide valuable information, while others may have information that is unreliable or misleading." Furthermore, because of the rapid increase in Internet-based information, many hours can be wasted searching, selecting, and printing. Since only the smallest fraction of information dealing with retinoblastoma is indexed in search engines, such as www.google.com or others, a non-systematic approach to Internet research can be not only time consuming, but also incomplete. This book was created for medical professionals, students, and members of the general public who want to conduct medical research using the most advanced tools available and spending the least amount of time doing so. ... Read more

Book Description
The article is excerpted fromGale Encyclopedia of Cancer
The resource students and researchers will turn to for reliable, up-to-date and clearly written information, the Gale Encyclopedia of Cancer is a comprehensive survey of 120 cancers, cancer drugs, traditional and alternative treatments and diagnostic procedures. The Encyclopediaincludes entries covering cancers, cancer drugs, treatments, side effects and diagnostic procedures. Entries typically include the following elements:

• Causes and Symptoms
• Definition
• Description
• Diagnosis
• Prevention
• Resources
• Risks
• Special Concerns
• And more

An appendix provides complete contact information for cancer centers, national support groups, government agencies and research groups. Features include anatomical illustrations of the major body systems, a subject index and approximately 200 photographs and drawings. ... Read more

Book Description
The article is excerpted fromGale Encyclopedia of Medicine.

Consult the second edition of this authoritative, comprehensive, in-depth medical guide for information on more than 1,700 medical topics in language accessible to adult laypersons. Presented in a single alphabetical sequence, articles range in length from one or two paragraphs for minor topics, to several pages or more for major topics. Disease/disorder articles typically cover definition; description; causes and symptoms; diagnosis; treatments; prevention; and more. Test/treatment articles typically cover definition; purposes; precautions; preparation; risks; normal and abnormal results; and much more. This second edition includes more than 200 new entries, 300 updated entries, approximately 650 color images and illustrations, and a comprehensive subject index. New features include biographical and historical sidebars throughout the text.

Disease/disorder articles contain some or all of the following sections:

• Definitions -- brief dictionary-style definition of the disorder
• Descriptions -- overview of the disorder; who gets it and why
• Causes & symptoms -- process, substance or organism that produces the condition; any risk factors that increase susceptibility to the condition; signs and symptoms of the disease
• Diagnosis -- overview of procedures and tests used to diagnose the condition; how the test is done; who should be tested and when; time required; cost; whether it's typically covered by insurance
• Treatments -- overview of conventional methods of care or management of the condition, such as drugs, surgeries, physical therapy, etc.
• Alternative treatments -- overview of alternative/complementary therapies that may be used to treat the condition
• Prognosis -- probable outcome of the disease
• Preventions -- what actions can be taken to prevent the condition from occurring

Book Description

Avoiding hard-to-understand medical jargon, the four-volume Gale Encyclopedia of Childrens Health uses language that parents can understand, while still providing enough depth to benefit today's health science students. The set provides in-depth coverage of pediatric diseases and disorders, along with issues related to physical and cognitive/behavioral development.

Book Description

Students, researchers, and patients can find reliable, up-to-date and clearly written information in The Gale Encyclopedia of Cancer, a comprehensive survey of 120 cancers, cancer drugs, traditional and alternative treatments and diagnostic procedures.

Book Description
This digital document is a journal article from Comparative Biochemistry and Physiology, Part C, published by Elsevier in 2007. The article is delivered in HTML format and is available in your Amazon.com Media Library immediately after purchase. You can view it with any web browser.

Description:
Xiphophorus interspecies hybrids provide several well-characterized genetic models of melanoma susceptibility. The Xiphophorus CDKN2A/B gene, homologous to mammalian CDKN2A/B cyclin-dependent kinase inhibitors (p16 and p15), is a candidate tumor susceptibility gene in these models. Using real-time PCR and Western blot analysis, we analyzed expression of CDKN2A/B in spontaneous and UV-induced primary melanomas from individual backcross hybrid fish. We found that CDKN2A/B mRNA is highly expressed in melanomas (18-fold), relative to other fish tissues. Expression is also elevated, to a lesser extent (9.5-fold), in melanized skin from tumor-bearing fish. However, quantitative levels of CDKN2A/B mRNA in tumors varied considerably and positively correlated with expression of the Xmrk oncogene, suggesting possible functional interaction between Xmrk and CDKN2A/B expression. As a homolog corresponding to members of the mammalian CDKN2 family which regulate cell cycle progression at the G1 checkpoint, the CDKN2A/B p13 protein is a putative regulator of the G1 checkpoint apparatus in Xiphophorus. Since CDKN2A is often observed to be inversely regulated compared to RB in some human tumors, and is capable of transcriptionally regulating RB in human ovarian tumors, we cloned the Xiphophorus maculatus RB cDNA and analyzed RB expression by real-time PCR and Western blot analysis in the fish melanomas. These experiments were designed to ascertain whether CDKN2A/B and RB expression were inversely correlated. Our results indicate that RB mRNA was consistently expressed at only a 2-fold higher level in both tumors and melanized skin than in muscle. Qualitatively similar results were obtained for protein expression. These results collectively suggest that (i) Xmrk and CDKN2A/B may be co-regulated at the transcriptional level, and (ii) there is little, if any, alteration of RB expression in Xiphophorus melanomas. ... Read more

Book Description
This digital document is a journal article from Comparative Biochemistry and Physiology, Part C, published by Elsevier in 2007. The article is delivered in HTML format and is available in your Amazon.com Media Library immediately after purchase. You can view it with any web browser.

Description:
The expression of protein biomarkers in Baltic Sea blue mussels was analyzed after three days exposure to low (2.8 @mg/animal/day), intermediate (28 @mg/animal/day), or high (280 @mg/animal/day) nominal doses of benzo[a]pyrene (BaP). Significant expression changes were found in the animals exposed to the low dose, the lowest reported dose for DNA adduct formation in the gills of Baltic Sea blue mussels. Up-regulated expression of the proliferating cell nuclear antigen (PCNA), quantified from Western blots, and no change in the 5-bromo-deoxyuridine (BrdU) staining pattern, determined by immunocytochemistry, indicated that the observed PCNA response was mainly non-proliferative, and thus possibly due to DNA damage. The expression of the multixenobiotic resistance polyglycoprotein (P-gp) was also up-regulated, proving its usefulness as an exposure marker to planar organic compounds. No effect of the BaP treatment with respect to the retinoblastoma 110 protein or heat shock proteins 60 and 70 was found. The variance in the medium and high dose data was too large to allow for the detection of significant expression changes. We suggest PCNA to be a marker for genotoxic stress derived from the polycyclic aromatic hydrocarbon BaP, irrespective of whether the stress leads to DNA repair or to cell proliferation. ... Read more

Book Description
The article is excerpted fromGale Encyclopedia of Medicine.

Consult the second edition of this authoritative, comprehensive, in-depth medical guide for information on more than 1,700 medical topics in language accessible to adult laypersons. Presented in a single alphabetical sequence, articles range in length from one or two paragraphs for minor topics, to several pages or more for major topics. Disease/disorder articles typically cover definition; description; causes and symptoms; diagnosis; treatments; prevention; and more. Test/treatment articles typically cover definition; purposes; precautions; preparation; risks; normal and abnormal results; and much more. This second edition includes more than 200 new entries, 300 updated entries, approximately 650 color images and illustrations, and a comprehensive subject index. New features include biographical and historical sidebars throughout the text.

Disease/disorder articles contain some or all of the following sections:

• Definitions -- brief dictionary-style definition of the disorder
• Descriptions -- overview of the disorder; who gets it and why
• Causes & symptoms -- process, substance or organism that produces the condition; any risk factors that increase susceptibility to the condition; signs and symptoms of the disease
• Diagnosis -- overview of procedures and tests used to diagnose the condition; how the test is done; who should be tested and when; time required; cost; whether it's typically covered by insurance
• Treatments -- overview of conventional methods of care or management of the condition, such as drugs, surgeries, physical therapy, etc.
• Alternative treatments -- overview of alternative/complementary therapies that may be used to treat the condition
• Prognosis -- probable outcome of the disease
• Preventions -- what actions can be taken to prevent the condition from occurring

Book Description
A Mother's Experience with Childhood Cancer.

Perfect Vision is a biographical tribute to kari, a little girl who used her inner vision and undaunted optimism to charm people and magically teach them compassion, understanding, and accceptance of others. Kari's love of life sings through her mother's words. ... Read more

Customer Reviews (2)

Heart warming story
Perfect Vision: A Mother's Experience With Childhood Caner was a very heart warming story.Sharon Higgins Brunner takes you through her daughters doctors visits, radiation therapy, chemotherapy, and her last and final breath.Although this was a very well written and good story, it did not go into much detail about the experiences with chemotherapy.It did not really tell what all her daughter went through, and how it changed her daughter.But, other than that I definetly recommend this story to anyone who wants a heartwarming story.

i am a pleased reader
This is a heart touching story of a mother and her childs battle with cancer. This book is about the joys and struggle of motherhood and the battle with cancer. The author of this book accuratly describes theexperence she and her child had with cancer ,and what it was like to be avictim of cancer. A way to describe this book is a non-stop trip throughthe real world in the eyes of a loving mother. I rate this book one of thebest i've read, i fell this gives the reader a "taste" of what itis like to be enlolved in such a situation. If you are intersted in thissucject i highly recomend this book to you. ... Read more

Book Description

Survival rates in cases of uveal melanoma and retinoblastoma - the leading intraocular malignancies in adults and children - may be high, but means of earlier diagnosis and improved treatment options are needed to preserve vision and prevent metastasis. This reference deals principally with the molecular biology and genetic factors which trigger and promote the two most common ocular tumours.

Book Description

Rb and Tumorigenesis examines how recent advances have demonstrated the interaction of Rb with chromatin remodeling enzymes. This new title explores the potential roles of these interactions in Rb functions and provides some evidence that distinct Rb co-repressor may target different genes in different phases of the cell cycle.