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This up-to-date and comprehensive set of two CD-ROM discs provides a superb collection of official Federal government documents on eye cancer, intraocular melanoma and retinoblastoma: signs and symptoms, diagnosis, lab tests, treatment and management options, and ongoing clinical research. Every aspect of the disease is thoroughly covered. Eye cancer forms in tissues of and around the eye. Some of the cancers that may affect the eye include melanoma (a rare cancer that begins in cells that make the pigment melanin in the eye), carcinoma (cancer that begins in tissues that cover structures in the eye), lymphoma (cancer that begins in immune system cells), and retinoblastoma (cancer that begins in the retina and usually occurs in children younger than 5 years).For patients, practical information is provided in clearly written patient education documents. For medical professionals, doctor references and texts have detailed technical information and clinical background material. Documents from the National Cancer Institute, Centers for Disease Control and Prevention (CDC), Food and Drug Administration (FDA), National Institutes of Health (NIH), Environmental Protection Agency (EPA), Medline, Centers for Medicare and Medicaid Services (CMS), and Occupational Health and Safety Administration (OSHA) are included. In addition to disease-specific information, there is extensive coverage of the broad subject of cancer and its prevention and treatment (surgery, chemotherapy, radiation, advanced treatments, managing side effects). There is no other reference that is as fast, convenient, and portable - everything you need to know, from the federal sources you trust.Since navigating the Internet to find medical information can be confusing, our exclusive "Guide to Leading Medical Websites 2009" has updated links to the 67 best sites! Weblinks let you quickly check for the latest clinical updates directly from the government and the best commercial portals, news sites, reference/textbook/non-commercial portals, and health organizations.Comprehensive cancer coverage includes: FDA Office of Oncology Drug Products, Oncology Tools - approved drugs, patient liaison * Dictionary of Cancer Terms (4000 items) * Division of Cancer Biology * Cancer Bulletin - archive of informative articles from NCI publication since 2004 * Cancers by Body Location, System * A-Z list of cancers * Clinical Trials * Complementary and Alternative Medicine * Coping - Complications and Side Effects - fatigue, pain, cardiopulmonary syndromes, cognitive disorders and delirium; fever, sweats, hot flashes; gastrointestinal complications, hypercalcemia; lymphedema; pruritus; sexuality and reproduction; sleep; nutrition; eating hints; emotions, anxiety, depression, adjustment, post-traumatic stress disorder; substance abuse; transitional care planning; radiation, home care, when cancer returns; Care for the Caregiver; Survivorship - end of life issues, advance directives, coping with advanced cancer, Hospice, Loss, Grief, and Bereavement * Division of Cancer Treatment and Diagnosis * Drug Development and Approval * Approved Oncology Drugs * Drug Dictionary - technical definitions and synonyms * Drug Information Summaries * Factsheets by cancer type, risk factors and possible causes, prevention, detection, diagnosis, therapy, support, coping, resources, tobacco and smoking cessation * Prevention, Genetics * Publications - specific cancers, treatment, trials, coping, testing, risks, nutrition * Screening and Testing * Support - organizations, finances and insurance * Chemotherapy, Radiation Therapy, Surgery, Cryosurgery, Laser, Hyperthermia, Targeted * Understanding Cancer - sixty-one publications * CDC Division of Cancer Prevention and Control * SEER Surveillance Epidemiology and End Results * Cancer Health Disparities * Cancer Centers Program. ... Read more

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Information on many genetic disorders, and the frequent new findings on them, has been extremely difficult to come by—until now. The “Gale Encyclopedia of Genetic Disorders” addresses the need for current, hard-to-find facts on emerging discoveries. The two-volume Encyclopedia, presented in a single alphabetical sequence, provides clear, complete information on genetic disorders, including conditions, tests, procedures, treatments and therapies, in articles that are both comprehensive and easy to understand, in language accessible to laypersons. The articles are arranged in a standardized format for quick comparison and ease of use, while non-disorder topics are covered in detail with extended entries. Students will want to consult the “Gale Encyclopedia of Genetic Disorders” for useful information on a range of well known disorders, including Down Syndrome, Trisomy, Hemophilia and Tourette Syndrome, and rarely seen diseases such as Meckel Syndrome, Neuraminidase Deficiency and Phenylketonuria.

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The revision of this classic major reference will continue to outline the latest findings in diagnosing children's eye diseases and their treatment options. The information in this edition will be presented in the same user-friendly format, heavily illustrated in color plates, tables, charts, and decision-making guidelines. This approach will enable the practitioner to make the most accurate diagnosis and choose the most effective treatment option. The highlights of this edition will include the new coverage of surgical treatment options and illustrated surgical techniques. Also, it will cover the most comprehensive list ever published of systematic syndromes associated with ocular anomalies. The most notable breakthroughs in the past 5 years in pediatric ophthalmology are reflected through the field of medical genetics. Therefore each chapter will be completely updated and revised in order to reflect these changes. ... Read more

Customer Reviews (1)

DR ADAM KOENIGSBERG MD REVIEW
This is an excellent text. I know Drs Spiegel and Wright personally. They do an excellent job of providing an extremely comprehensive text on pediatric ophthalmology and strabismus. Adam Koenigsberg MD ... Read more

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Pediatric retinal diseases are not simply retinal diseases that occur in children; rather, they are unique disorders that often are not found in adults. This textbook of the pediatric retina offers in-depth guidance on congenital and acquired diseases of the retina in the pediatric population. It is organized according to disease onset and timing, as well as anatomy. All chapters are written by leading authorities in the field from both the pediatric and the retinal perspective. A multidisciplinary approach to the topic is adopted, and critical information is included on disease classification and diagnosis, pathophysiology, genetics, complications, and prognosis. Pediatric Retina will be a useful source of information for pediatric ophthalmologists, retina specialists, and other eye care providers who care for children. ... Read more

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This digital document is an article from Gale Encyclopedia of Medicine, 3rd ed., brought to you by Gale®, a part of Cengage Learning, a world leader in e-research and educational publishing for libraries, schools and businesses.The length of the article is 1555 words.The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase.You can view it with any web browser.The third edition of this authoritative, comprehensive, in-depth medical guide features information on medical topics in language accessible to adult laypersons. Disease/disorder articles typically cover definition; description; causes and symptoms; diagnosis; treatments; prevention; and more. Test/treatment articles typically cover definition; purposes; precautions; preparation; risks; normal and abnormal results; and much more. ... Read more

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This digital document is a journal article from Comparative Biochemistry and Physiology, Part C, published by Elsevier in 2007. The article is delivered in HTML format and is available in your Amazon.com Media Library immediately after purchase. You can view it with any web browser.

Description:
The expression of protein biomarkers in Baltic Sea blue mussels was analyzed after three days exposure to low (2.8 @mg/animal/day), intermediate (28 @mg/animal/day), or high (280 @mg/animal/day) nominal doses of benzo[a]pyrene (BaP). Significant expression changes were found in the animals exposed to the low dose, the lowest reported dose for DNA adduct formation in the gills of Baltic Sea blue mussels. Up-regulated expression of the proliferating cell nuclear antigen (PCNA), quantified from Western blots, and no change in the 5-bromo-deoxyuridine (BrdU) staining pattern, determined by immunocytochemistry, indicated that the observed PCNA response was mainly non-proliferative, and thus possibly due to DNA damage. The expression of the multixenobiotic resistance polyglycoprotein (P-gp) was also up-regulated, proving its usefulness as an exposure marker to planar organic compounds. No effect of the BaP treatment with respect to the retinoblastoma 110 protein or heat shock proteins 60 and 70 was found. The variance in the medium and high dose data was too large to allow for the detection of significant expression changes. We suggest PCNA to be a marker for genotoxic stress derived from the polycyclic aromatic hydrocarbon BaP, irrespective of whether the stress leads to DNA repair or to cell proliferation. ... Read more

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This digital document is an article from Gale Encyclopedia of Surgery, brought to you by Gale®, a part of Cengage Learning, a world leader in e-research and educational publishing for libraries, schools and businesses.The length of the article is 1356 words.The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase.You can view it with any web browser.Written by experts in the field, this encyclopedia covers surgical procedures and related topics, such as anesthetics, medications, and postoperative care. Entries include definition, purpose, demographic information, diagnosis/preparation, aftercare, risks, morbidity, and mortality rates, alternatives, and more. ... Read more

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University of Wisconsin, Madison. Research on the cellular genes thought to be regulated by the E2F gene family. For researchers. 8 U.S. contributors. ... Read more

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The article is excerpted fromGale Encyclopedia of Medicine.

Consultthe second edition of this authoritative, comprehensive, in-depthmedical guide for information on more than 1,700 medical topics inlanguage accessible to adult laypersons. Presented in a singlealphabetical sequence, articles range in length from one or twoparagraphs for minor topics, to several pages or more for major topics.Disease/disorder articles typically cover definition; description;causes and symptoms; diagnosis; treatments; prevention; and more.Test/treatment articles typically cover definition; purposes;precautions; preparation; risks; normal and abnormal results; and muchmore. This second edition includes more than 200 new entries, 300updated entries, approximately 650 color images and illustrations, anda comprehensive subject index. New features include biographical andhistorical sidebars throughout the text.

Disease/disorder articles contain some or all of the following sections:

• Definitions -- brief dictionary-style definition of the disorder
• Descriptions -- overview of the disorder; who gets it and why
• Causes & symptoms -- process, substance or organism thatproduces the condition; any risk factors that increase susceptibilityto the condition; signs and symptoms of the disease
• Diagnosis -- overview of procedures and tests used todiagnose the condition; how the test is done; who should be tested andwhen; time required; cost; whether it's typically covered by insurance
• Treatments -- overview of conventional methods of care ormanagement of the condition, such as drugs, surgeries, physicaltherapy, etc.
• Alternative treatments -- overview of alternative/complementary therapies that may be used to treat the condition
• Prognosis -- probable outcome of the disease
• Preventions -- what actions can be taken to prevent the condition from occurring

Test/treatment articles contain some or all of the following sections:

• Definitions -- brief dictionary-style definition of the test/treatment
• Purposes -- why and when this test/treatment is prescribed
• Precautions -- when this test/treatment should not be prescribed
• Descriptions -- overview of the test/treatment including cost,length of time required, procedures followed, whether typically coveredby insurance
• Preparation -- pre-test treatment procedures, if any
• Aftercare -- post-test treatment procedures, if any
• Risks -- any complications/side effects commonly associated with the test/treatment
• Normal results -- for tests, describes the normal values; for treatments, describes the anticipated outcomes
• Abnormal results -- defines abnormal test values

Published/Released: December 2001

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This book highlights the unique aspects of oncologic ophthalmology as a medical and surgical discipline practiced at a comprehensive cancer center. Multi-disciplinary management of ocular, orbital and adnexal cancers are highlighted using simple and tried-and-true algorithms. In addition, ocular problems caused as a direct result of cancer treatment are reviewed using illustrative photographs and case presentations. The content is provided by full-time ophthalmology faculty and fellows at M. D. Anderson Cancer Center. Experts in complementary disciplines such as ophthalmic pathology, dermatopathology, radiation oncology, radiology, and other surgical subspecialties have brought their unique perspective to each chapter.

The book is abundant with clinical photographs as well as interesting case presentations that will help the clinician correctly diagnose cancers of the orbit, eye, and adnexal structures, initiate appropriate management, as well as recognize and treat common ocular complications of cancer therapy.

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Survival rates in cases of uveal melanoma and retinoblastoma—the leading intraocular malignancies in adults and children—may be high, but means of earlier diagnosis and improved treatment options are needed to preserve vision and prevent metastasis. A timely volume with a unique scientific focus, Ocular Oncology is the only reference to deal principally with the molecular biology and genetic factors triggering and promoting the two most common ocular tumors. ... Read more

Customer Reviews (1)

A lot of information expert to due internet research
This book helped my understanding, but unless you are a Dr plan to spend a few hours reading this then using the internet to better understand what is being said ... expect some confusion. I worked at the time in the medical device industry so a little easier for me to read and understand.

Useful to anyone with such Ocular medical issues that wants to learn the details. ... Read more

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Customer Reviews (1)

Good but not great
I now own this "text" and the previously published "atlas" on intraocular tumors by the Shields, as well as oncology books by several other authors. If you own the "atlas", I am not sure it is worthwhile to purchase this new text. Here is why.

This book is filled with great pictures of anterior segment and posterior segment tumors as well as masquerading entities. However, many of the pictures are carried over from the "Atlas of intraocular tumors." The pictures are very good though.

The format in this book is similar to the "atlas" as well where at the beginning of a section, there is a brief and somewhat cursory discussion of the topic.They do not go into the nitty-gritty details of tumor management, study results, etc.What was most frustrating was situations where the Shields would mention that there are distinguishing features between this tumor and this problem, but would not go into further detail to say what those distinguishing features are..clinically, or on FA, or on ultrasound.Also, they show photos of tumors of the same variety that were treated with different modalities and don't specify why (plaque radiotherapy vs surgical excision vs enucleating, etc..). There are many other examples where the text is lacking.

So, I think this is mainly just a new edition of their "Atlas" rather than a true textbook on intraocular tumors. The photos are great, the text is no better than what you would find in a general ophthalmology text.

Currently, the best oncology TEXT is the somewhat old now book by Devron Char, "Tumors of the Eye and Ocular Adenxa." I find the text to contain an adequare amount of detail on the diseases and their management.The "Ocular Oncology" text by Albert is pretty good, but does not have the beautiful photos other books do and sometimes gets bogged down in basic science work. ... Read more

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Thomas Jefferson Univ., Philadelphia, PA. One of three atlases on ocular tumors. Text appears on the left-hand page, with illustrations on the facing page. Abundant, high-quality color and halftone illustrations are included. For oncologists, pathologists, ophthalmologists, and residents. ... Read more

Customer Reviews (1)

Great Pictures
This is an excellent atlas for intraocular tumors. The photos are very nice and the captions succinct.My only complaint is that the text could be more complete in terms of clinical descriptions and distinguishing characteristics of certain lesions both clinically and on diagnostic testing.

Also, there is not much detail in terms of study results or tumor management...ie why one tumor was treated with sclerouveaectomy and another with TTT and another plaque radiotherapy.One can sometimes surmise this, but it would be nice if they explained their clinical decision making for the examples they show.

Tips and pearls regarding their surgical techniques would have been a nice addition also...but I guess you have to be a fellow there to get that. ... Read more