21. Polymyositis polymyositis is an inflammatory muscle disease that causes varyingdegrees of decreased muscle power. Subscribe now . polymyositis. http://healthlink.mcw.edu/article/921449523.html

Search Articles: search tips Please Take the HealthLink Survey Email this article Print this article Find related articles: By topic: Neurology By keywords: Receive Health Link via email! Subscribe now >> Polymyositis Polymyositis is an inflammatory muscle disease that causes varying degrees of decreased muscle power. The disease has a gradual onset and generally begins in the second decade of life. Polymyositis rarely affects persons under the age of 18. The most common symptom is muscle weakness, usually affecting those muscles that are closest to the trunk of the body (proximal). Eventually, patients have difficulty rising from a sitting position, climbing stairs, lifting objects, or reaching overhead. In some cases, distal muscles (those not close to the trunk of the body) may also be affected later in the course of the disease. Trouble with swallowing (dysphagia) may occur. Occasionally, the muscles ache and are tender to touch. Patients may also feel fatigue and discomfort and have weight loss or a low-grade fever. Treatment for polymyositis generally consists of a steroid drug called prednisone. For patients in whom prednisone is not effective, immunosuppressants such as azathioprine and methotrexate may be prescribed. Physical therapy is usually recommended to preserve muscle function and avoid muscle atrophy.

22. Inflammatory Myopathy polymyositis. polymyositis Clinical features Muscle weakness Proximal Distal;Symmetric; Selective regions of weakness Dysphagia; Posterior neck; Quadriceps. http://www.neuro.wustl.edu/neuromuscular/antibody/infmyop.htm

Front Search Index Links ... Patient Info Inflammatory and Immune Myopathies GENERAL FEATURES Antibodies CK: Serum Electrodiagnostic ... Calcinosis : X-rays Chondroitin sulfate C deficient Dermatomyositis Fasciitis Focal myositis ... Signal recognition particle Vasculitis: Small Large vessel SPECIFIC IMMUNE OR INFLAMMATORY MYOPATHIES Polymyositis syndromes General aspects Classification Comparative features Collagen vascular disease Complement ... Quadriceps ; Other TRAPS Granulomatous Hemophagocytic lymphohistiocytosis Hereditary ... Multinodular polymyositis Necrotizing with Encephalopathy Paraneoplastic with Pipestem capillaries SRP antibodies ... MHC class I upregulation Skin lesions Erythema Gottron's papules Nailfold lesions From: Chinju, South Korea GENERAL FEATURES OF INFLAMMATORY MYOPATHIES Antibodies CK: Serum Electrodiagnostic Neoplasm associations ... Weakness Skin lesions Heliotrope rash Distribution Symmetric Disease association: Dermatomyositis External links Facial rash Gottron's sign Red-purple keratotic, atrophic erythema, or macules Disease association: Dermatomyositis External link: Gottron's sign Erythema Red-purple slightly raised On extensor surfaces of elbows or knees Disease association: Dermatomyositis Mechanic's hands Raised scaly dry On extensor surfaces of finger joints Disease association: Nailfold lesions Disease association: Dermatomyositis - Anti-Mi-2 antibody positive Other features Rash more commonly pruritic than rash with lupus erythematosis Skin lesions often photoaggravated Weakness Proximal: Most Dermatomyositis Polymyositis Distal:

23. POLYMYOSITIS polymyositis. 1) Boyd,AS, Neldner,KH Therapeutic options in dermatomyositis/polymyositis.Internat J Dermatol 33240250,1994. Cyclosporine. Neoral. http://www.neuro.wustl.edu/neuromedical_treatment/polymyos.html

POLYMYOSITIS Treatment is long term immunosuppression, in the largest number of reported patients with PO corticosteroids, in the event of steroid toxicity supplemented at lower steroid doses with azathioprine or, in a few cases, with cyclosporine. Supplementation with methotrexate has also been reported but there are many toxicities to be considered. IV immunoglobulin has been used successfully in a small number of patients, alone or with other immunosuppressants.....the major difficulty is cost, not toxicity. A satisfactory response to immunosuppressants may be expected in two-thirds of the patients, or more. The only favorable experience in inclusion body myositis has been reported, in a few cases, with IV immunoglobulin. Azathioprine Imuran. Tab 50 mg. Begin with 50 mg od increased by 50 mg increments at weekly intervals until a dose of 2-3 mg/kg od is reached. The daily amount may be given in a single dose or in divided doses bid. Maintainance dose thereafter is determined by clinical response and WBC....in regard to the latter, 3-4 K/cmm is the value desired. The response, if it occurs, is typically delayed, the time from onset of treatment varying from 3 to 12 months. Time to maximal improvement varies from 1 to 2 years. Judgement regarding response should not be made before 1 year of treatment has been completed. The drug may be used alone or with a corticosteroid. Studies report 60-70% success. Until a stable maintainance dose has been reached liver chemistries and a CBC should be done weekly, then every 2 months. Hepatotoxicity is less than with methotrexate. For gastric distress sucralfate (Carafate) may be prescribed. 10% of patients develope a hypersensitivity reaction with fever, abdominal symptomatology, malaise and, sometimes, a rash.....if so, treatment with this agent is terminated at once without gradual reduction and not resumed.

24. Polymyositis polymyositis, See Also Dermatomyositis. Types Type 1 Primary Idiopathicpolymyositis (33%); Type 2 Primary Idiopathic Dermatomyositis (25%); http://www.fpnotebook.com/RHE19.htm

Home About Links Index ... Editor's Choice Paid Advertisement (click above). Please see the privacy statement Rheumatology Diffuse Assorted Pages Amyloidosis Antiphospholipid Antibody Syndrome Systemic Lupus Erythematosus Polymyalgia Rheumatica ... Medication Causes of Myositis Polymyositis Book Home Page Cardiovascular Medicine Dental Dermatology Emergency Medicine Endocrinology Gastroenterology General Medicine Geriatric Medicine Gynecology Hematology and Oncology HIV Infectious Disease Jokes Laboratory Neonatology Nephrology Neurology Obstetrics Ophthalmology Orthopedics Otolaryngology Pediatrics Pharmacology Prevention Psychiatry Pulmonology Radiology Rheumatology Sports Medicine Surgery Urology Chapter Rheumatology Index Bone Cardiovascular Medicine Diffuse Examination Infectious Disease Intra-Articular Disorders Laboratory General Marfans Myofascial Neurology Osteoarthritis Pain Pediatrics Pharmacology Procedure Radiology RA Spondylitis Symptom Evaluation Page Diffuse Index Amyloidosis Behcets Syndrome Lupus Anticoagulant Lupus Systemic Polymyalgia Rheumatica Polymyositis Background Polymyositis DDx Polymyositis Evaluation Polymyositis Management Polymyositis Types Idiopathic Scleroderma Sjogren's See Also Dermatomyositis Types Type 1: Primary Idiopathic Polymyositis Type 2: Primary Idiopathic Dermatomyositis Type 3: Neoplasia related Type 4: Childhood disease with Vasculitis Type 5: Collagen Vascular disease related Type 6: Miscellaneous (Inclusion body

25. Polymyositis Evaluation polymyositis Evaluation Dermatomyositis Evaluation. Signal Recognition Particle (SRP)Seen in 5% of polymyositis; Associated in severe, acuteonset polymyositis http://www.fpnotebook.com/RHE21.htm

Home About Links Index ... Editor's Choice Paid Advertisement (click above). Please see the privacy statement Rheumatology Diffuse Assorted Pages Amyloidosis Antiphospholipid Antibody Syndrome Systemic Lupus Erythematosus Polymyalgia Rheumatica ... Medication Causes of Myositis Polymyositis Evaluation Dermatomyositis Evaluation Book Home Page Cardiovascular Medicine Dental Dermatology Emergency Medicine Endocrinology Gastroenterology General Medicine Geriatric Medicine Gynecology Hematology and Oncology HIV Infectious Disease Jokes Laboratory Neonatology Nephrology Neurology Obstetrics Ophthalmology Orthopedics Otolaryngology Pediatrics Pharmacology Prevention Psychiatry Pulmonology Radiology Rheumatology Sports Medicine Surgery Urology Chapter Rheumatology Index Bone Cardiovascular Medicine Diffuse Examination Infectious Disease Intra-Articular Disorders Laboratory General Marfans Myofascial Neurology Osteoarthritis Pain Pediatrics Pharmacology Procedure Radiology RA Spondylitis Symptom Evaluation Page Diffuse Index Amyloidosis Behcets Syndrome Lupus Anticoagulant Lupus Systemic Polymyalgia Rheumatica Polymyositis Background Polymyositis DDx Polymyositis Evaluation Polymyositis Management Polymyositis Types Idiopathic Scleroderma Sjogren's See Also Polymyositis Dermatomyositis Labs: Muscle Enzymes Serum Aldolase Alanine Aminotransferase (ALT) Aspartate Aminotransferase (AST) Lactate Dehydrogenase (LDH) Creatine Phosphokinase (CPK) Carbonic Anhydrase (isoenzyme III) Limited availability Lab: General Erythrocyte Sedimentation Rate (ESR) Increased in 50% of cases

26. Myositis - About Myositis inflammation). Myositis refers to several different illnesses, includingpolymyositis, dermatomyositis, and inclusion body myositis. http://www.orthop.washington.edu/arthritis/types/myositis/01

Home About Us Clinics Physicians ... Contact Us Table of contents About myositis What is myositis? Incidence and risk factors Prognosis ... View article with questions External links Myositis Association of America [Top] Myositis Edited by Frederick A. Matsen, III, M.D. Last updated May 1, 2002 About myositis What is myositis? Myositis is the term for illnesses that involve chronic muscle inflammation ("myo" means muscle and "itis" means inflammation). "Myositis" refers to several different illnesses, including polymyositis, dermatomyositis, and inclusion body myositis. All forms of myositis involve chronic, or persistent, muscle inflammation. This muscle inflammation almost always results in weakness, and less often in heat, swelling, and pain of the muscles. Myositis can affect many parts of the body. Sometimes the joints, heart, lungs, intestines, and skin can become inflamed. Some forms of myositis, like dermatomyositis ("dermato" refers to the skin), result in particular rashes over the knuckles, around the eyes, or sometimes in other parts of the body. Other forms of myositis occur in children. Some forms are seen with other connective tissues diseases, like lupus or rheumatoid arthritis . Still other forms may occur in people with tumors. Rarely, myositis can occur in a single part of the body, such as one arm, one leg, or just the muscles that move the eye.

27. 1Up Health > Polymyositis (adult) > Causes, Incidence, And Risk Factors Of Polym Comprehesive information on polymyositis (adult) . 1Up Health Diseases Conditions polymyositis (adult) Causes, Incidence, and Risk Factors. http://www.1uphealth.com/health/polymyositis_adult_info.html

1Up Health Polymyositis (adult) Alternative Medicine Clinical Trials ... Health Topics A-Z Search 1Up Health Polymyositis (adult) Information Polymyositis (adult) Causes, Incidence, and Risk Factors Definition : A systemic connective tissue disease, which is characterized by inflammation and degeneration of the muscles. Causes, Incidence, and Risk Factors The cause of this disorder is unknown. It is thought that an autoimmune reaction or a viral infection of the skeletal muscle may cause the disease. It can affect people at any age, but most commonly occurs in those between 50 to 70 years old, or in children between 5 to 15 years old. It affects women twice as often as men. Muscle weakness may appear suddenly or occur slowly over weeks or months. There may be difficulty with raising the arms over the head, rising from a sitting position, or climbing stairs. The voice may be affected through weakness of the throat muscles. Joint pain inflammation of the heart , and pulmonary (lung) disease may occur. A similar condition, called dermatomyositis , is evident when a dusky, red rash appears over the face, neck, shoulders, upper chest, and back. A

28. Polymyositis Diary polymyositis Adam a diary of my PM experiences (Sounds like a badchildren's book, but it's the only title I could think of.) http://home.sprintmail.com/~edam/polym.html

a diary of my PM experiences (Sounds like a bad children's book, but it's the only title I could think of.) Most Recent Entry : March 19, 2003 Visit the Diary Archive for entries relating my first two years with PM. I am now in my third diagnosed year of living with the disease. NOTES : This page assumes a general knowledge of what myositis and polymyositis are. If you clicked to this page before visiting my links page and you want to get the basics on this disease, visit this site I am not a medical professional, and have no medical training. This diary relates my personal experience, my conversations with my doctors, and the research I've been able to obtain from books, the internet, other myositis patients, and medical journals. How I'm Doing (for specific details, see the most recent diary entry) Medical Conditions Condition Status Polymyositis: Anti-Jo-1 Positive PM Related Interstitial Lung Disease Inactive Migraines Managed Chronic Headaches Inactive* Medications Dosage Methotrexate (oral) 10 mg/week Immitrex (oral) 50 mg tablets as needed Folic Acid (prescribed supplement) 1 mg/day Mobic 7.5 mg 1-2 times/day as needed

29. Page 34 Home polymyositis and Dermatomyositis. polymyositis and dermatomyositis(PMDM) are autoimmune neuromuscular diseases. They are sometimes http://www.aarda.org/page34.html

Polymyositis and Dermatomyositis Polymyositis and dermatomyositis (PM-DM) are autoimmune neuromuscular diseases. They are sometimes referred to as connective tissue diseases. Polymyositis and dermatomyositis can occur in all ages and both sexes, although they are more common in women; and childhood disease is differentiated from the adult type. A recent study (Nurse Health Study 1976-1990) found that the incidence of polymyositis affects approximately 120 women per million. The clinical hallmark of these diseases is proximal limb and neck weakness, sometimes associated with muscle pain. A skin rash on the face and upper chest area is present in dermatomyositis, distinguishing it from polymyositis. There is usually an elevated blood level of CPK. Autoimmune factors are felt to be important, because autoantibodies are present in most patients. Some of the antibodies found in myositis are anti-Jo-1, anti-PL-12, anti-EJ, anti-OJ, anti-Mi-2, anti-MAS, anti-Fer, and anti-SRP. For more information on polymyositis and dermatomyositis or other autoimmune disorders, please click on the request information icon below.

30. Medic-Planet Polymyositis polymyositis Advertisement See also Muscles, Back to the Index page CauseDoctors do not know what initiates polymyositis or dermatomyositis . http://www.medic-planet.com/MP_article/internal_reference/Polymyositis

31. Medic-Planet Polymyositis polymyositis Advertisement See also Muscles, Back to the Index page CauseDoctors do not know what initiates polymyositis or dermatomyositis . http://www.medic-planet.com/MP_article/internal_reference/polymyositis

32. Polymyositis MAIN SEARCH INDEX polymyositis. Definition. polymyositis is an inflammatorymuscle disease causing weakness and pain. Dermatomyositis http://www.hendrickhealth.org/healthy/001093.htm

MAIN SEARCH INDEX Polymyositis Definition Description Causes and symptoms Diagnosis ... Resources Definition Polymyositis is an inflammatory muscle disease causing weakness and pain . Dermatomyositis is identical to polymyositis with the addition of a characteristic skin rash. Description Polymyositis (PM) is an inflammatory disorder in which muscle tissue becomes inflamed and deteriorates, causing weakness and pain. It is one of several types of inflammatory muscle disease, or myopathy. Others include dermatomyositis (DM) and inclusion body myositis. All three types are progressive conditions, usually beginning in adulthood. A fourth type, juvenile dermatomyositis, occurs in children. Although PM and DM can occur at any age, 60% of cases appear between the ages of 30 and 60. Females are affected twice as often as males. Causes and symptoms Causes The cause of PM and DM is not known, but it is suspected that a variety of factors may play a role in the development of these diseases. PM and DM may be autoimmune diseases, caused by the immune system's attack on the body's own tissue. The reason for this attack is unknown, although some researchers believe that a combination of immune system susceptibility and an environmental trigger may explain at least some cases. Known environmental agents associated with PM and DM include infectious agents such as Toxoplasma Borrella Lyme disease bacterium), and coxsackievirus. Most cases, however, have no obvious triggers (direct causative agents). There may also be a genetic component in the development of PM and DM.

33. Polymyositis Translate this page polymyositis. Antworten Ihre Antwort Forum www.medizin-ring.de Suchedringend Kontakt zu Menschen denen die Krankheit polymyositis etwas sagt. http://www.medizin-ring.de/forum/messages/23.html

polymyositis Antworten Ihre Antwort Forum www.medizin-ring.de Abgeschickt von billygirl am 21 April, 2002 um 12:26:39 Suche dringend Kontakt zu Menschen denen die Krankheit Polymyositis etwas sagt. Leide seit 2 Jahren an dieser Krankheit. Bin für alle Informationen und Erfahrungsaustausch dankbar. Antworten: Re: polymyositis Claudia Re: polymyositis Elvira Re: polymyositis Claudia Re: polymyositis Elvira Re: polymyositis Claudia Re: polymyositis Elvira Re: polymyositis Sven Re: polymyositis Claudia Re: polymyositis Sven Re: polymyositis Claudia Re: polymyositis Sven Re: polymyositis Claudia Re: polymyositis Sven Re: polymyositis Sven Re: polymyositis Andrea Re: polymyositis Claudia Re: polymyositis Sven Re: polymyositis Andrea Re: polymyositis Sven Re: polymyositis Andrea Re: polymyositis Sven Re: polymyositis Sven Re: polymyositis Andrea Re: polymyositis ute Re: polymyositis Andrea Re: polymyositis Dirk Lammert Re: polymyositis Andrea Re: polymyositis Rita Fischhöfer Re: polymyositis Sabine Distler Re: polymyositis Sabine Distler Re: polymyositis Sabine Distler Re: polymyositis Distler Sabine Re: polymyositis Barbara Pilawa Re: polymyositis Anke Re: polymyositis Yvi Re: polymyositis Barcal Silvia Re: polymyositis anja Re: polymyositis Alexa Re: polymyositis Hans koslowsky Ihre Antwort Name: E-Mail: Subject: Text: : Suche dringend Kontakt zu Menschen denen die Krankheit Polymyositis etwas sagt. Leide seit 2 Jahren an dieser Krankheit. : Bin für alle Informationen und Erfahrungsaustausch dankbar.

34. Re: Polymyositis Translate this page Re polymyositis. Antworten Ihre Antwort Forum www.medizin-ring.de Antwortauf polymyositis von billygirl am 21 April, 2002 um 122639 Hallöle,. http://www.medizin-ring.de/forum/messages/55.html

Re: polymyositis Antworten Ihre Antwort Forum www.medizin-ring.de Abgeschickt von Rita Fischhöfer am 06 Januar, 2003 um 20:07:17 Antwort auf: polymyositis von billygirl am 21 April, 2002 um 12:26:39: Hallöle, ich leide zwar nicht selber an dieser Krankheit, jedoch ist meine Freundin seit ca. 4 Jahren davon betroffen. Da sie auf der Suche nach einer Selbsthilfegruppe ist, kann ich auf diesem Weg ja vielleicht ne Info bekommen. Gruß Rita Antworten: Re: polymyositis Sabine Distler Re: polymyositis Sabine Distler Re: polymyositis Sabine Distler Re: polymyositis Distler Sabine Ihre Antwort Name: E-Mail: Subject: Text: : Hallöle, : ich leide zwar nicht selber an dieser Krankheit, jedoch ist meine Freundin seit ca. 4 Jahren davon betroffen. Da sie auf der Suche nach einer Selbsthilfegruppe ist, kann ich auf diesem Weg ja vielleicht ne Info bekommen. : Gruß Rita Optionale URL: Link Titel: Optionale Bild-URL: Antworten Ihre Antwort Forum www.medizin-ring.de

35. Juvenile Dermatomyositis And Polymyositis Juvenile Dermatomyositis and polymyositis A Followup Study of Long-termSequelae. CRAIG H. COLLISON, SARA H. SINAL, MD, JOSEPH http://www.sma.org/smj1998/jansmj98/3text.htm

Juvenile Dermatomyositis and Polymyositis A Follow-up Study of Long-term Sequelae CRAIG H. COLLISON, SARA H. SINAL, MD, JOSEPH L. JORIZZO, MD, FRANCIS O. WALKER, MD, JOHNNY U. V. MONU, MD, and JANE SNYDER, PT, Winston-Salem, NC Abstract Background. Juvenile dermatomyositis/polymyositis (JDMS/PM) are childhood inflammatory myopathies that normally affect children between 2 and 15 years of age. The disease is manifested as severe proximal muscle weakness and, in JDMS, as a characteristic cutaneous eruption. It is difficult to predict the course of the disease. This study is aimed at objectively assessing the long-term morbidity of dermatomyositis/polymyositis in children. Methods. Twelve cases of JDMS/PM identified through chart review were evaluated by physical and dermatologic examination, muscle testing, ultrasonography, and magnetic resonance imaging (MRI). Conclusions. Multiple physical and dermatologic sequelae are commonly present in patients with JDMS/PM on long-term follow-up, but these do not preclude a productive life. Ultrasonography and MRI provide additional noninvasive means of analysis, but because of the current high cost, MRI is not routinely recommended. JUVENILE dermatomyositis/polymyositis (JDMS/PM) is a childhood form of inflammatory myopathy usually affecting children from 2 to 15 years of age. It is manifested by severe proximal muscle weakness and, in JDMS, by a characteristic cutaneous eruption. Other less common signs and symptoms include dysphagia, cardiac conduction abnormalities, and restrictive ventilatory dyspnea.1-3 Polymyositis (PM) has the same features as JDMS but without the cutaneous involvement.

36. Bronchiolitis Obliterans Organizing Pneumonia As The First Manifestation Of Poly Bronchiolitis Obliterans Organizing Pneumonia as the First Manifestation of polymyositis. Quadricepsfemoris muscle biopsy was compatible with polymyositis. http://www.sma.org/smj/97feb13.htm

Bronchiolitis Obliterans Organizing Pneumonia as the First Manifestation of Polymyositis FARID FATA, MD, RITESH RATHORE, MD, CARL SCHIFF, MD, and BARRY C. HERZLICH, MD, Brooklyn, NY ABSTRACT: Bronchiolitis obliterans organizing pneumonia (BOOP) preceding polymyositis is rare. In this report, a 51-year-old patient with fever, nonproductive cough, and dyspnea had bilateral basal interstitial infiltrates on chest roentgenogram. Open lung biopsy was consistent with BOOP. Prednisone therapy led to improvement, but 8 weeks later, fever, cough, and weakness of the arms and legs developed because the patient had not been compliant with the prednisone regimen. The creatine kinase (CK), the macrophage inflammatory protein (MIP-1), and the tumor necrosis factor (TNF-a a levels declined significantly. This is only the second reported case of BOOP preceding polymyositis. Patients with idiopathic BOOP should have follow-up for the possible development of connective tissue disorders including polymyositis. THE PULMONARY MANIFESTATIONS of polymyositis include usual interstitial pneumonitis, bronchiolitis obliterans, diffuse alveolar damage, pulmonary capillaritis, and bronchiolitis obliterans organizing pneumonia (BOOP).1,2 In 1985, Epler et al3 described BOOP as a distinct entity. BOOP presents with fever associated with cough and dyspnea. Pathologically, although there is a cellular interstitial pneumonitis, the organizing pneumonia consists of proliferating fibroblasts that lay down mucopolysaccharides and young connective tissue.4 The entity must be distinguished from bronchiolitis obliterans, which affects only the distal bronchioles, and from organizing pneumonitis and organizing diffuse alveolar damage, which affect only the alveoli.4 BOOP preceding or coexisting with polymyositis is rare. We report the second case of BOOP preceding polymyositis5 and show that cytokines play a role in the pathogenesis of BOOP associated with polymyositis.

37. Florida State University College Of Medicine Digital Library Dermatomyositis and polymyositis Patient/Family Resources. Miscellaneous Dermatomyositisand polymyositis Patients/Family Resources Healthfinder Homepage http://fsumed-dl.slis.ua.edu/patientinfo/rheumatology/autoimmune/dermatomyositis

Patient/Family Resources by Topic: Musculoskeletal Disorders Dermatomyositis and Polymyositis Patient/Family Resources Pediatrics Spanish Miscellaneous See also: General Rheumatology Patient/Family Resources Dermatomyositis and Polymyositis Clinical Resources Arthritis Foundation: Homepage Disease Center: List of documents Dermatomyositis: Access document Myositis (Polymyositis Dermatomyositis) Access document American College of Rheumatology: Homepage Patient Information: List of documents Myopathies Access document American Autoimmune Related Diseases Association: Homepage Medical Information: List of documents Polymyositis and Dermatomyositis: Access document American Pain Foundation: Homepage Consumer Health Information: List of documents Connective Tissue Diseases: Access document MEDLINE plus Medical Encyclopedia: Table of contents Dermatomyositis: English Spanish Polymyositis (Adult): English Spanish InteliHealth Disease and Condition Guide Table of contents Myositis (Polymyositis And Dermatomyositis): Access document Merck Manual Home Edition Table of contents Chapter 51. Disorders of Joints and Connective Tissue:

38. Florida State University College Of Medicine Digital Library Dermatomyositis and polymyositis Clinical Resources. Miscellaneous Dermatomyositisand polymyositis Clinical Resources HealthWeb Homepage http://fsumed-dl.slis.ua.edu/clinical/rheumatology/autoimmune/dermatomyositis.ht

Clinical Resources by Topic: Musculoskeletal Disorders Dermatomyositis and Polymyositis Clinical Resources Emergency Pediatrics Geriatrics Atlases ... Miscellaneous Resources See also: Musculoskeletal Clinical Procedure Resources General Rheumatology Clinical Resources Dermatomyositis and Polymyositis Patient/Family Resources Harrison's Principles of Internal Medicine 15th Ed.-2001: Table of contents Medical Library subscription INFO Chapter 382: Polymyositis, Dermatomyositis, and Inclusion Body Myositis Table of contents Introduction: Access document General Clinical Features Access document Specific Features Access document Associated Clinical Findings Access document Pathogenesis Access document Differential Diagnosis Access document Diagnosis Access document Treatment Access document Prognosis Access document Chapter 58: Immunologically Mediated Skin Diseases: Table of contents Introduction: Access document Diseases with Prominent Cutaneous Features: Access document Dermatomyositis: Access document Chapter 275: Glomerulopathies Associated with Multisystem Diseases: Table of contents Introduction: Access document Immunologically Mediated Multisystem Diseases: Access document Introduction: Access document Polymyositis and Dermatomyositis: Access document Chapter 259: Interstitial Lung Diseases: Table of contents Introduction: Access document Pathogenesis: Access document Introduction: Access document Granulomatous Lung Disease: Access document Inflammation and Fibrosis: Access document Initial Evaluation: Access document Introduction: Access document History:

39. POLYMYOSITIS STEVE, polymyositis In late april of 1997 I was diagnosed with polymyositis.My CPK level was 7,956. It all started in mid to late http://www.rheumatic.org/steve.htm

STEVE, polymyositis In late april of 1997 I was diagnosed with polymyositis. My CPK level was 7,956. It all started in mid to late january 97 with a pain in the calf of my right leg; then aches and pains with burning muscles that got progressively worse with each passing week. Swallowing became very difficult. It was like I had the worst case of the flu ever, multiplied by a thousand. Finally I went to my GP doctor. I was tested for hepatitis, liver disease, weeks of those tests with nothing confirmed. Then I saw his associate in his absence and she wanted me to have a special test (CPK). Meanwhile a friend of mine had a bad bacterial infection that was going around and she had taken Zithromax (azithromycin) to get rid of it. I thought that was probably what I had and was sure it would help me, because my symptons were the same, only more severe. So I made a deal with the doctor - I'd go immediately for the CPK test if she would give me a prescription for Zithromax. She agreed to do that, then stated it wouldn't help. That's when I had a CPK count of 7,956. But the Zithromax did help me quite a bit. The next day I was able to lift my arms, etc.

40. POLYMYOSITIS LIANNE, polymyositis My life is my own once again! Two years agoI was diagnosed with polymyositis. I was devastated. I was a http://www.rheumatic.org/lianne.htm

LIANNE, polymyositis My life is my own once again! Two years ago I was diagnosed with polymyositis. I was devastated. I was a business owner, single parent, and a professional skater. I was so very tired, in a lot of pain, and, most of all, I feared for my life. Prior to being diagnosed I went from doctor to doctor trying to figure out what was wrong with me. I thought I was having an allergic reaction. I went to a third allergist. She interrogated me for over an hour. She ran a series of blood tests and discovered I had an elevated CPK. She confronted me assuming I was a cocaine addict and felt that must be the cause of my problem. I explained I didn't do drugs, but by the sound of the alternatives I almost wished that was the problem. I was sent to a rheumatologist. My diagnosis was confirmed by a muscle biopsy and an EMG. In that same breath that was used to give me the diagnosis, I was told that I had to have an AIDS test. I freaked. She failed to explain that the drugs she was going to prescribe were going to suppress my immune system and if I had AIDS, it would speed up my death. A psychiatrist had read to me all about being a hypochondriac, and I was told I was the healthiest looking sick person she had ever seen. When I told her how scared I was waiting for the AIDS test results, she told me, "You don't have AIDS. You had better hope you don't have polymyositis - you can die from that."

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