Extractions: Dateline: 12/07/97 (Updated and expanded: 12/31/97) Early in the AIDS epidemic, there were fears that as many as 40% of HIV-infected people might develop neurological problems due to HIV's effects on the brain. In practice, the true figure has been very much lower. One possibility is that anti-HIV drugs have helped to prevent these problems. As summarized in NAM's short factsheet on dementia, HIV-related brain impairment has been given several different names, including AIDS dementia complex or ADC. Last week the American Medical Association published a detailed overview of current thinking on how HIV affects the central nervous system. And of course, apart from HIV's direct effects, opportunistic infections such as toxoplasmosis and cryptococcal meningitis can also affect the brain. The CDC has just published a new brochure on avoiding toxoplasmosis. More information is also contained in Project Inform's factsheet on dementia. Studies in the late 1980s, including two placebo-controlled trials conducted by the
Speakeasy Guide - A ADC See aids dementia complex. The exact cause of aids dementia complexis unknown but it is associated with an HIV infection of the brain. http://www.quac.org.au/qpp/services/speakeasy/speaka.htm
Extractions: Introduction/Terminology Prevalence Diagnostic Criteria Introduction/Terminology ref Secondary to the effect of opportunistic infections of the CNS The direct effect HIV-1 virus encephalopathy has been termed the "AIDS dementia complex" with synonyms of HIV-associated dementia and HIV-associated cognitive motor complex. The Working Group of the American Academy of Neurology AIDS Task Force proposed the term "HIV-1-associated cognitive/motor complex" for the AIDS dementia complex & subdivided associated conditions [ ref Mild manifestations Prevalence: Prior to availability of antiviral therapy for HIV, ~60% of HIV-1 infected patients developed HIV-1-associated dementia [
ASHM What is aids dementia complex? There is a care guide available AIDS DementiaComplex. A Guide to Management and Care at Home, van Reyke P, May 1997. http://www.ashm.org.au/index.php?&PageCode=106
University Of Sydney Medical Library. Medline Guide. AIDS Arteritis, Central Nervous System, 0, aids dementia complex, 1905, AIDSArteritis, Central Nervous System, 0, aids dementia complex, 1905, http://www.library.usyd.edu.au/subjects/medicine/medltree.html
Extractions: Subject search ... Medical Library home Mapping Tree Display Explode Focus ... Interactive Tutorial The tree can be displayed, from the mapping screen, by clicking on the hypertext link for the relevant subject heading. The tree display allows the searcher to: The tree is arranged conceptually with broader and narrower branches relating to each specific term. The broader term is always at the left of the screen and narrower terms are indented. Some headings are found in more than one branch of the tree structure. To view other branches click on the Contexts button located at the top left of the screen.
Protease Inhibitors May Reverse AIDS Dementia In the United States, about one third of the adults and half of the children withAIDS eventually develop aids dementia complex, with symptoms that range from http://jama.ama-assn.org/issues/v279n6/ffull/jmn0211-3.html
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Publications Trypsin inhibition a potential cause of cobalamin deficiency common to thepathogenesis of Alzheimertype dementia and aids dementia complex?. http://www.mccaddon.demon.co.uk/cobalz/publics.htm
Types Of Dementia Also, the increased incidence of aids dementia complex, which results from HIVinfection, helps account for the increased dementia in recent history. http://www.cchs.net/health/health-info/docs/2300/2340.asp?index=9170
Harvard AIDS Institute The AIDS Report-Fall 1993 Diagnosing aids dementia complex Accurate diagnosis and treatment of neuropsychiatricproblems can make a dramatic difference in quality of life for people http://www.hsph.harvard.edu/hai/news_publications/tar/fall93/fall93-3.html
Searchalot Directory For AIDS Dementia Complex Related Web Sites. aids dementia complex This article is from theDec. MedicineNet - A brief article about aids dementia complex. http://www.searchalot.com/Top/Health/ConditionsandDiseases/NeurologicalDisorders
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KlinPsy - Neuropsychologie AidsDementie. Organisaties Ziekte Tom Peters Aids and the nervous systema focus on the aids dementia complex . Bowers Mark aids dementia complex . http://users.glo.be/allemeesch/KlinPsy/Neuropsy.htm
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NPEL: Neuropathology Of AIDS intracellulare Cytomegalovirus Progressive Multifocal Leukoencephalopathy HerpesSimplex Virus Varicella Zoster Virus aids dementia complex Vacuolar myelopathy http://www.uvm.edu/~jkessler/NP/neuAIDS.htm
Extractions: OBJECTIVES: The objectives of this hour are to recognize the central and peripheral nervous systems as primary targets of the infectious agent of AIDS, to be aware of some of the opportunistic infections and neoplasms of the CNS that affect AIDS patients, and to become familiar with the most frequent neuropathologic lesion of AIDS, the AIDS Dementia Complex.
Opioid Analogue May Slow Spread Of HIV In Brain In some HIVinfected patients, HIV-1 infection in the brain leads to a disease syndromecalled aids dementia complex, which results in apathy, difficulties http://www.drugabuse.gov/NIDA_Notes/NNVol11N4/Opioid.html
Extractions: September/October 1996 By Neil Swan , NIDA NOTES Staff Writer Synthetic compounds, or analogues, related to the opiates morphine and heroin can limit the growth of HIV - the virus that causes AIDS - in the brain, according to NIDA-funded research findings. The study with human cell culture suggests that a synthetic compound that binds to the brain's kappa opioid receptors (KOR) may curtail a virus subtype called HIV-1 from spreading in the brains of people infected with the AIDS virus. A drug analogue is a chemical compound that differs slightly from another drug. Although the study was performed in cell culture, the results suggest the possibility that a medication could be developed to prevent a particularly destructive aspect of AIDS - the loss of intellectual capacity. This research is part of a broad range of NIDA-supported studies of the complex relationship between drugs of abuse and AIDS, including studies of the effects of drug use on the body's immune system and, subsequently, on infection and disease progression. The study also provides an example of how research on drugs of abuse can have benefits in other areas of medicine. In some HIV-infected patients, HIV-1 infection in the brain leads to a disease syndrome called "AIDS dementia complex," which results in apathy, difficulties in muscle control and movement, and problems in performing complex tasks. The mental capacity of patients with dementia complex may deteriorate until they are incapable of voluntary acts.
Extractions: The nervous system has two parts. The brain and spinal cord are the central nervous system (CNS). The nerves and muscles are the peripheral nervous system. Peripheral means around the outside. People with HIV disease can have several nerve problems. A common problem is peripheral neuropathy. This causes nerve and muscle pain, especially in the feet, legs, and hands. See Fact Sheet 555 for more information. CNS problems include depression and problems with sleeping, balance, walking, thinking and memory. At first, these were all called "AIDS Dementia Complex". However, there is a wide range of AIDS-related nerve troubles. AIDS Dementia means ongoing major problems with thinking, memory, and usually also with controlling the legs and arms. Before combination antiviral therapy was available, about 20% of people with AIDS developed dementia. There are many fewer cases now. The exact rate is not known.
UBC SON: Faculty And Staff (1997). Nursing care guidelines for people with aids dementia complex. Wyness, MA(1994). aids dementia complex Guidelines for nursing care. Axon 16, 3746. http://www.school.nursing.ubc.ca/faculty/facultydir/wyness_Anne.asp
Extractions: Recent Funded Projects Preoperative Education and Information Needs of Patients and Key Family Members Related to Surgical Management of Skull Base Neoplasms, (Principle Investigator, M. Borozny). World Federation of Neurosciences Nurses, Agnes Marshall Research Award, $3000 (U.S.), 1997 - 2001 Outcome Evaluation of N. 409D - HIV/AIDS: The Challenge of Caring, Health Canada, $4,863, 1998.
MSN Health - What Is Dementia, From The Cleveland Clinic Also, the increased incidence of aids dementia complex, which results from HIV infection,helps account for the increased dementia in recent history, although http://content.health.msn.com/content/article/45/1626_50487
Extractions: Dementia is the loss of mental functions such as thinking, memory, and reasoning that is severe enough to interfere with a person's daily functioning. Dementia is not a disease itself, but rather a group of symptoms that are caused by various diseases or conditions. Symptoms can also include changes in personality, mood, and behavior. In some cases, the dementia can be treated and cured because the cause is treatable. Examples of this include dementia caused by drugs or alcohol, or hormone or vitamin imbalances. In some cases, although the person may appear to have dementia, a severe depression can be causing the symptoms. This is known as pseudo-dementia (false dementia) and is highly treatable. In most cases, however, dementia cannot be cured. Dementia develops when the parts of the brain that are involved with learning, memory, decision-making, and language are affected by one or more of a variety of infections or diseases. The most common cause of dementia is Alzheimer's disease, but there are as many as 50 other known causes. Most of these causes are very rare.